Exhibit
10.145


 


PIGGY-BACK
REGISTRATION RIGHTS AGREEMENT


 


THIS
PIGGY-BACK REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of April 14, 2022, is made by and between
RespireRx Pharmaceuticals Inc., a Delaware corporation (the “Company”), and Barton Asset Management LLC a Delaware
limited liability company (the “Holder”). The Company and the Holder are hereinafter sometimes collectively referred
to as the “Parties” and each a “Party” to this Agreement.


 


RECITALS


 


WHEREAS,
the Company’s Board of Directors (the “Board”) has unanimously approved, upon the terms and subject to the conditions
of, that certain Securities Purchase Agreement, of even date herewith, by and between the Holder and the Company (the “Securities
Purchase Agreement”), the Company has agreed to issue and sell to Holder the Note (as defined in the Securities Purchase Agreement)
(the “Note”) and Warrant (as defined in the Securities Purchase Agreement) (the “Warrant”), to
the Holder; and


 


WHEREAS,
to induce the Holder to execute and deliver the Securities Purchase Agreement and this Agreement, the Company has agreed to provide certain
piggy-back registration rights under the Securities Act of 1933, as amended (the “Securities Act”) and the rules and
regulations promulgated thereunder, and applicable state securities laws, with respect to the Piggy-Back Registrable Securities (as
defined herein).


 


NOW,
THEREFORE, for and in consideration of the foregoing premises, the agreements and covenants herein contained, and other good and
valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Company and the Holder, intending to be legally
bound, hereby agree as follows:


 


1.
Definitions. As used in this Agreement, the following terms shall have the following meanings:


 


a.
[Intentionally Omitted].


 


b.
“Effective Date” shall mean the date the SEC declares the Registration Statement effective and the Company has filed
all necessary amendments, including the letter to request accelerated effectiveness and the Prospectus covering the resale of Piggy-Back
Registrable Securities.


 


c.
“Filing Date” shall mean the date the Registration Statement has been filed with the SEC (as determined by EDGAR)
and no stop order of acceptance has been issued by the SEC.


 


d.
“Person” means a corporation, a limited liability company, an association, a partnership, an organization, a business,
an individual, a governmental or political subdivision thereof or a governmental agency.


 


e.
“Principal Market” means either the NYSE American, the Nasdaq Global Select Market, the Nasdaq Global Market, the
Nasdaq Stock Capital Market, OTCQX® Best Market, the OTCQB® Venture Market or the OTC Pink Market, whichever is the principal
market on which the Securities is listed or quoted.


 


f.
“Purchase Amount” means the Purchase Price, as such term is defined in the Securities Purchase Agreement.


 


g.
“Register”, “Registered” and “Registration” refer to a registration effected
by preparing and filing with the SEC one or more Registration Statements in compliance with the Securities Act and/or pursuant to Rule
415 under the Securities Act or any successor rule providing for among other securities, the Piggy-Back Registrable Securities.


 


h.
“Piggy-Back Registrable Securities” means the Conversion Shares (as defined in the Securities Purchase Agreement)
(the “Conversion Share”), Warrant Shares (as defined in the Securities Purchase Agreement) (the “Warrant
Shares”), all other shares of Common Stock issued or issuable pursuant to the Securities Purchase Agreement, and any shares
of capital stock issued or issuable with respect to such Note, Conversion Shares, Warrant, or Warrant Shares as a result of any stock
split, stock dividend, recapitalization, exchange or similar event or otherwise, which have not been (x) included in a Registration Statement
that has been declared effective by the SEC, (y) sold under circumstances meeting all of the applicable conditions of Rule 144, promulgated
under the Securities Act or (z) saleable without limitation as to time, manner and volume pursuant to Rule 144(k) (or any similar provision
then in force) under the Securities Act.


 




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i.
“Registration Statement” means a registration statement of the Company filed with the SEC under the Securities Act.


 


j.
“SEC” means the United States Securities and Exchange Commission.


 


All
capitalized terms used but not defined in this Agreement shall have the meaning ascribed to them in the Securities Purchase Agreement;
provided however, that any references to Conversion Price shall have the meaning ascribed to it in the Note (the “Conversion
Price”).


 


2.
Registration.


 


a.
Piggy-Back Registration. With respect to only one of the first three times the Company files a Registration Statement under the
Securities Act, and at the request of the Holder, the Company shall use its commercially reasonable efforts, to the extent permissible
under U.S. securities laws and the rules and regulations thereunder, to include the Piggy-Back Registrable Securities in such Registration
Statement with the intention of covering the resale of all of the Piggy-Back Registrable Securities at prevailing market prices (and
not fixed prices). The Company shall, to the extent permissible by U.S. securities laws and the rules and regulations thereunder initially
register for resale all of the Piggy-Back Registrable Securities, or an amount equal to the maximum amount allowed under the applicable
rule or rules as interpreted by the SEC. In the event the Company cannot register the Piggy-Back Registrable Securities, due to the remaining
number of authorized shares (including shares held in the share reservation established for the benefit of the Holder) of Common Stock
being insufficient, the Company will use its best efforts to register the maximum number of shares it can, based upon the remaining balance
of authorized shares (including shares held in the share reservation established for the benefit of the Holder) and will use its best
efforts to increase the number of its authorized shares as soon as reasonably practicable.


 


b.
The Company shall use its commercially reasonable efforts, if it elects to file a Registration Statement and to the extent permissible
under U.S. securities laws, to have the Registration Statement filed with the SEC within sixty (60) days following Holder’s request
for the inclusion of the Piggy-Back Registrable Securities in such Registration Statement (the “Filing Deadline”).


 


Notwithstanding
the foregoing, failure to file by the Filing Deadline shall not constitute an event of default under the Note to the extent any delay
in the filing of the Registration Statement occurs because of an act of, or a failure to act or to act timely by the Holder or is otherwise
solely attributable to the Holder.


 


The
Company acknowledges that its failure to have the Registration Statement filed by the Filing Deadline will cause the Holder to suffer
irreparable harm, and, that damages will be difficult to ascertain. Accordingly, the Parties agree that it is appropriate that the failure
to file by the Filing Deadline shall constitute an event of default under Section 3.3 of the Note. The availability of any remedies hereunder
and thereunder shall not relieve the Company from its obligations to register the Piggy-Back Registrable Securities and deliver the Piggy-Back
Registrable Securities pursuant to the terms of this Agreement and the Securities Purchase Agreement.


 


c.
The Company shall use its efforts and take all available steps to have the Registration Statement declared effective by the SEC within
ninety (90) calendar days after the Filing Date (the “Effective Deadline”). If the Registration Statement covering
the Piggy-Back Registrable Securities to be filed by the Company pursuant to Section 2(a) hereof has not become effective by the
Effective Deadline, then it shall constitute an event of default under Section 3.3 of the Note.


 


If
the Registration Statement covering the Piggy-Back Registrable Securities to be filed by the Company pursuant to Section 2(a)
hereof has become effective, and, thereafter, the Holder’s right to sell is suspended, for any reason, then the Company shall pay
the Holder the sum of one percent (1%) of the Purchase Amount plus interest and penalties due to the Holder under the Note for each thirty
(30) calendar day period, pro rata, compounded annually, following the suspension, until such suspension ceases (the “Suspension
Damages”). The Suspension Damages shall continue until the obligation is fulfilled and shall be paid within five (5) business
days after each thirty (30) day period, or portion thereof, until such suspension is released. The Suspension Damages shall be paid,
at the Holder’s option, in cash or shares of the Company’s common stock, par value $0.001, priced at the Conversion Price
(as defined in the Note), or portion thereof. Failure of the Company to make payment within said five (5) business days after each thirty
(30) day period shall be considered a breach of this Agreement and an event of default under Section 3.3 of the Note.


 




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Notwithstanding
the foregoing, the amounts payable by the Company pursuant to this Section 2(c) shall not be payable to the extent any delay in
the effectiveness of the Registration Statement or any suspension of the effectiveness occurs because of an act of, or a failure to act
or to act timely by the Holder or is otherwise solely attributable to the Holder.


 


The
Company acknowledges that its failure to have the Registration Statement become effective by the Effective Deadline or to permit the
suspension of the effectiveness of the Registration Statement, will cause the Holder to suffer irreparable harm and, that damages will
be difficult to ascertain. Accordingly, the Parties agree that it is appropriate to include in this Agreement a provision for liquidated
damages. The Parties acknowledge and agree that the liquidated damages provision set forth in this Section 2(c) represents the
Parties’ good faith effort to quantify such damages and, as such, agree that the form and amount of such liquidated damages are
reasonable and will not constitute a penalty. The payment of liquidated damages shall not relieve the Company from its obligations to
register the Piggy-Back Registrable Securities and deliver the Piggy-Back Registrable Securities pursuant to the terms of this Agreement
and the Securities Purchase Agreement.


 


3.
Related Obligations.


 


At
such time as the Company is obligated to prepare and file a Registration Statement with the SEC pursuant to Section 2(a) hereof,
the Company will use its best efforts to effect the registration of the Piggy-Back Registrable Securities in accordance with the intended
method of disposition thereof and, with respect thereto, the Company shall have the following obligations:


 


a.
The Company shall use its best efforts to cause such Registration Statement relating to the Piggy-Back Registrable Securities to become
effective within ninety (90) calendar days after the Filing Date and shall keep such Registration Statement effective pursuant to Rule
415 under the Securities Act until the date on which the Holder shall have sold all the Piggy-Back Registrable Securities (the “Registration
Period”), which Registration Statement (including any amendments or supplements thereto and prospectuses contained therein)
shall, as of the date thereof, not contain any untrue statement of a material fact or omit to state a material fact required to be stated
therein, or necessary to make the statements therein, in light of the circumstances in which they were made, not misleading.


 


b.
The Company shall prepare and file with the SEC such amendments (including post-effective amendments) and supplements to a Registration
Statement and the prospectus used in connection with such Registration Statement, which prospectus is to be filed pursuant to Rule 424
under the Securities Act, as may be necessary to keep such Registration Statement effective during the Registration Period, and, during
such period, comply with the provisions of the Securities Act with respect to the disposition of all Piggy-Back Registrable Securities
of the Company covered by such Registration Statement until such time as all of such Piggy-Back Registrable Securities shall have been
disposed of in accordance with the intended methods of disposition by the Holder as set forth in such Registration Statement (which shall
be at prevailing market prices, and not fixed prices). In the event the number of shares available under a Registration Statement filed
pursuant to this Agreement is at any time insufficient to cover all of the Piggy-Back Registrable Securities, the Company shall amend
such Registration Statement, or file a new Registration Statement (on the short form available therefor, if applicable), or both, so
as to cover all of the Piggy-Back Registrable Securities, in each case, as soon as practicable, but in any event within thirty (30) calendar
days after the necessity therefor arises (based on the total number of Piggy-Back Registrable Securities). The Company shall use it best
efforts to cause such amendment and/or new Registration Statement to become effective as soon as practicable following the filing thereof.


 


c
The Company shall furnish to the Holder whose Piggy-Back Registrable Securities are included in any Registration Statement and its legal
counsel without charge and upon request (i) promptly after the same is prepared and filed with the SEC at least one copy of such Registration
Statement and any amendment(s) thereto, including financial statements and schedules, all documents incorporated therein by reference
and all exhibits, the prospectus included in such Registration Statement (including each preliminary prospectus) and, with regards to
such Registration Statement(s), any correspondence by or on behalf of the Company to the SEC or the staff of the SEC and any correspondence
from the SEC or the staff of the SEC to the Company or its representatives, (ii) upon the effectiveness of any Registration Statement,
a copy of the prospectus included in such Registration Statement and all amendments and supplements thereto (or such other number of
copies as the Holder may reasonably request) and (iii) such other documents, including copies of any preliminary or final prospectus,
as the Holder may reasonably request from time to time in order to facilitate the disposition of the Piggy-Back Registrable Securities.
The Company filing the documents described in this paragraph through EDGAR shall constitute delivery.


 




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d.
The Company shall use reasonable efforts to (i) register and qualify the Piggy-Back Registrable Securities covered by a Registration
Statement under the applicable securities or “blue sky” laws of such states of the United States as reasonably specified
by the Holder; (ii) prepare and file in those jurisdictions, such amendments (including post-effective amendments) and supplements to
such registrations and qualifications as may be necessary to maintain the effectiveness thereof during the Registration Period; (iii)
take such other actions as may be necessary to maintain such registrations and qualifications in effect at all times during the Registration
Period; and (iv) take all other actions reasonably necessary or advisable to qualify the Piggy-Back Registrable Securities for sale in
such jurisdictions; provided, however, that the Company shall not be required in connection therewith or as a condition thereto to (x)
qualify to do business in any jurisdiction where it would not otherwise be required to qualify but for this Section 3(d), (y)
subject itself to general taxation in any such jurisdiction, or (z) file a general consent to service of process in any such jurisdiction.
The Company shall promptly notify the Holder who holds Piggy-Back Registrable Securities of the receipt by the Company of any notification
with respect to the suspension of the registration or qualification of any of the Piggy-Back Registrable Securities for sale under the
securities or “blue sky” laws of any jurisdiction in the United States or its receipt of actual notice of the initiation
or threatening of any proceeding for such purpose.


 


e.
Upon the happening of any event as a result of which the prospectus included in a Registration Statement, as then in effect, would then
contain an untrue statement of a material fact or omission to state a material fact, which would otherwise be required to be stated therein
or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading; and, as a result,
the prospectus is required to be supplemented or as a result of which the Registration Statement is required to be amended (“Registration
Default”), the Company shall use all diligent efforts to promptly prepare any necessary supplement to such prospectus or amendment
to such Registration Statement and take any other necessary steps to cure the Registration Default, and deliver one (1) copy of such
supplement or amendment to Holder (or such other number of copies as Holder may reasonably request; delivery via EDGAR shall constitute
delivery). Failure to cure the Registration Default within five (5) business days shall result in the Company paying liquidated damages
of one percent (1%) of the Purchase Amount for each thirty (30) calendar day period or portion thereof, beginning on the date of suspension.
The Company shall also promptly notify Holder in writing (i) when a prospectus or any prospectus supplement or post-effective amendment
has been filed, and when a Registration Statement or any post-effective amendment has become effective (notification of such effectiveness
shall be delivered to Holder by facsimile on the same day of such effectiveness and by overnight mail); (ii) in the event the Registration
Statement is no longer effective; or (iii) the Registration Statement is stale for a period of more than five (5) trading days as a result
of the Company’s failure to timely file its financials with the SEC.


 


The
Company acknowledges that its failure to cure the Registration Default within five (5) business days will cause the Holder irreparable
harm, and that damages will be difficult to ascertain. Accordingly, the Parties agree that it is appropriate to include in this Agreement
a provision for liquidated damages. The Parties acknowledge and agree that the liquidated damages provision set forth in this Section
3(e) represents the Parties’ good faith effort to quantify such damages and, as such, agree that the form and amount of such
liquidated damages are reasonable and will not constitute a penalty.


 


It
is the intention of the Parties that interest payable under any of the terms of this Agreement shall not exceed the maximum amount permitted
under any applicable law. If a law, which applies to this Agreement which sets the maximum interest amount, is finally interpreted so
that the interest in connection with this Agreement exceeds the permitted limits, then: (1) any such interest shall be reduced by the
amount necessary to reduce the interest to the permitted limit; and (2) any sums already collected (if any) from the Company which exceed
the permitted limits will be refunded to the Company. The Holder may choose to make this refund by reducing the amount that the Company
owes under this Agreement or by making a direct payment to the Company. If a refund reduces the amount that the Company owes the Holder,
the reduction will be treated as a partial payment. In the event that any provision of this Agreement is held by a court of competent
jurisdiction to be excessive in scope or otherwise invalid or unenforceable, such provision shall be adjusted rather than voided, if
possible, so that it is enforceable to the maximum extent possible, and the validity and enforceability of the remaining provisions of
this Agreement will not in any way be affected or impaired thereby.


 


f.
The Company shall use its best efforts to prevent the issuance of any stop order or other suspension of effectiveness of a Registration
Statement, or the suspension of the qualification of any of the Piggy-Back Registrable Securities for sale in any jurisdiction and, if
such an order or suspension is issued, to obtain the withdrawal of such order or suspension at the earliest possible moment and to notify
the Holder of the issuance of such order and the resolution thereof. The Company will immediately notify the Holder of a proceeding,
or threat of proceeding, the result of which could affect the effectiveness of the registration statement.


 




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g.
[RESERVED]


 


h.
[RESERVED]


 


i.
The Company shall hold in confidence and not make any disclosure of information concerning the Holder unless (i) disclosure of such information
is necessary to comply with federal or state securities laws, (ii) the disclosure of such information is necessary to avoid or correct
a misstatement or omission in any Registration Statement, (iii) the release of such information is ordered pursuant to a subpoena or
other final, non-appealable order from a court or governmental body of competent jurisdiction, or (iv) such information has been made
generally available to the public other than by disclosure in violation of this Agreement or any other agreement. The Company agrees
that it shall, upon learning that disclosure of such information concerning a Holder is sought in or by a court or governmental body
of competent jurisdiction or through other means, give prompt written notice to the Holder and allow the Holder, at the Holder’s
expense, to undertake appropriate action to prevent disclosure of, or to obtain a protective order for, such information.


 


j.
The Company shall use its best efforts to secure designation and quotation of all the Piggy-Back Registrable Securities covered by any
Registration Statement on the Principal Market, to the extent such is necessary for the Piggy-Back Registrable Securities to trade on
such market. If, despite the Company’s best efforts, the Company is unsuccessful in satisfying this obligation, it shall use its
best efforts to cause all the Piggy-Back Registrable Securities covered by any Registration Statement to be listed on each other national
securities exchange and automated quotation system, if any, on which securities of the same class or series issued by the Company are
then listed, if any, if the listing of such Piggy-Back Registrable Securities is then permitted under the rules of such exchange or system.
If, despite the Company’s best efforts, the Company is unsuccessful in satisfying its obligation in this Section, it will use its
best efforts to secure the inclusion for quotation with the OTC Pink Sheets. The Company shall pay all fees and expenses in connection
with satisfying its obligation under this Section 3(j).


 


k.
The Company shall cooperate with the Holder to facilitate the timely preparation and delivery of book-entry or street name shares(not
bearing any restrictive legend) representing the Piggy-Back Registrable Securities to be offered pursuant to a Registration Statement
and enable such certificates to be in such denominations or amounts, as the case may be, as the Holder may reasonably request and registered
in such names of the Persons who shall acquire such Piggy-Back Registrable Securities from the Holder, as the Holder may request.


 


l.
The Company shall provide a transfer agent for all the Piggy-Back Registrable Securities not later than the Effective Date of the first
Registration Statement filed pursuant hereto.


 


m.
If requested by the Holder, the Company shall (i) as soon as reasonably practical, incorporate in a prospectus supplement or post-effective
amendment such information as Holder reasonably determines should be included therein relating to the sale and distribution of Piggy-Back
Registrable Securities, including, without limitation, information with respect to the Note, Conversion Shares, Warrant, and Warrant
Shares; (ii) make all required filings of such prospectus supplement or post-effective amendment as soon as notified of the matters to
be incorporated in such prospectus supplement or post-effective amendment; and (iii) supplement or make amendments to any Registration
Statement if reasonably requested by Holder.


 


n.
The Company shall use its best efforts to cause the Piggy-Back Registrable Securities covered by the applicable Registration Statement
to be registered with or approved by such other governmental agencies or authorities as may be necessary to consummate the disposition
of such Piggy-Back Registrable Securities.


 


o.
[RESERVED]


 


p.
The Company shall otherwise use its best efforts to comply with all applicable rules and regulations of the SEC in connection with any
registration hereunder.


 


q.
Within five (5) business days after the Registration Statement which includes the Piggy-Back Registrable Securities is declared effective
by the SEC, the Company shall deliver to the Holder confirmation that such Registration Statement has been declared effective by the
SEC.


 




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r.
After the SEC declares the Registration Statement cleared of all comments and the Company’s acceptance of the effectiveness of
the Registration Statement, the Company shall file a prospectus covering the resale of the Piggy-Back Registrable Securities (the “Prospectus”)
within five (5) trading days.


 


s.
The Company shall take all other reasonable actions necessary to expedite and facilitate disposition by the Holder of the Piggy-Back
Registrable Securities pursuant to a Registration Statement.


 


4.
Obligations Of The Holder.


 


a.
At least five (5) calendar days prior to the first anticipated filing date of a Registration Statement, the Company shall notify the
Holder in writing of the information the Company requires from the Holder. The Holder covenants and agrees that, in connection with any
resale of Piggy-Back Registrable Securities by it pursuant to a Registration Statement, it shall comply with the “Plan of Distribution”
section of the current prospectus relating to such Registration Statement, and such “Plan of Distribution” shall include
Holder’s resale of the Piggy-Back Registrable Securities at prevailing market prices (and not fixed prices).


 


b.
The Holder, by the Holder’s acceptance of the Piggy-Back Registrable Securities, agrees to cooperate with the Company as reasonably
requested by the Company in connection with the preparation and filing of any Registration Statement hereunder and in responding to SEC
comments in connection therewith.


 


c.
The Holder agrees that, upon receipt of any notice from the Company of the happening of any event of the kind described in Section
3(f) hereof or the first sentence of Section 3(e) hereof, the Holder will immediately discontinue disposition of Piggy-Back
Registrable Securities pursuant to any Registration Statement(s) covering such Piggy-Back Registrable Securities until Holder’s
receipt of the copies of the supplemented or amended prospectus contemplated by Section 3(f) hereof or the first sentence of Section
3(e) hereof.


 


5.
Expenses Of Registration.


 


All
expenses, including, without limitation, all registration, listing and qualifications fees, printing and accounting fees, and reasonable
fees and disbursements of counsel for the Company shall be paid by, and are the sole obligation of, the Company.


 


6.
Indemnification.


 


In
the event any Piggy-Back Registrable Securities are included in a Registration Statement under this Agreement:


 


a.
To the fullest extent permitted by law, the Company will, and hereby agrees to, indemnify, hold harmless and defend the Holder who holds
such Piggy-Back Registrable Securities, the directors, officers, partners, employees, agents, representatives of, and each Person, if
any, who controls Holder within the meaning of the Securities Act or the Exchange Act) (each, an “Indemnified Person”),
against any losses, claims, damages, liabilities, judgments, fines, penalties, charges, costs, reasonable attorneys’ fees, amounts
paid in settlement or reasonable expenses, joint or several (collectively, “Claims”), incurred in investigating, preparing
or defending any action, claim, suit, inquiry, proceeding, investigation or appeal taken from the foregoing by or before any court or
governmental, administrative or other regulatory agency, body or the SEC, whether pending or threatened, whether or not an indemnified
party is or may be a party thereto (Indemnified Damages”), to which any of them may become subject insofar as such Claims
(or actions or proceedings, whether commenced or threatened, in respect thereof) arise out of or are based upon: (i) any untrue statement
or alleged untrue statement of a material fact in a Registration Statement or any post-effective amendment thereto or in any filing made
in connection with the qualification of the Note under the securities or other “blue sky” laws of any jurisdiction in which
Piggy-Back Registrable Securities are offered (“Blue Sky Filing”), or the omission or alleged omission to state a
material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which the
statements therein were made, not misleading, (ii) any untrue statement or alleged untrue statement of a material fact contained in the
final prospectus (as amended or supplemented, if the Company files any amendment thereof or supplement thereto with the SEC) or the omission
or alleged omission to state therein any material fact necessary to make the statements made therein, in light of the circumstances under
which the statements therein were made, not misleading, or (iii) any violation or alleged violation by the Company of the Securities
Act, the Exchange Act, any other law, including, without limitation, any state securities law, or any rule or regulation thereunder relating
to the offer or sale of the Piggy-Back Registrable Securities pursuant to a Registration Statement (the matters in the foregoing clauses
(i) through (iii) being, collectively, “Violations”). Subject to the restrictions set forth in Section 6(c)
hereof with respect to the number of legal counsel, the Company shall reimburse the Holder and each such controlling person, promptly
as such expenses are incurred and are due and payable, for any reasonable legal fees or other reasonable expenses incurred by them in
connection with investigating or defending any such Claim. Notwithstanding anything to the contrary contained herein, the indemnification
agreement contained in this Section 6(a): (i) shall not apply to a Claim arising out of or based upon a Violation committed by
any Indemnified Person or which occurs in reliance upon and in conformity with information furnished in writing to the Company by any
Indemnified Person expressly for use in connection with the preparation of the Registration Statement or any such amendment thereof or
supplement thereto, if such prospectus were timely made available by the Company pursuant to Section 3(c) hereof; (ii) shall not
be available to the extent such Claim is based on (a) a failure of the Holder to deliver or to cause to be delivered the prospectus made
available by the Company or (b) the Indemnified Person’s use of an incorrect prospectus despite being promptly advised in advance
by the Company in writing not to use such incorrect prospectus; and (iii) shall not apply to amounts paid in settlement of any Claim
if such settlement is effected without the prior written consent of the Company, which consent shall not be unreasonably withheld. Such
indemnity shall remain in full force and effect regardless of any investigation made by or on behalf of the Indemnified Person and shall
survive the resale of the Piggy-Back Registrable Securities by the Holder pursuant to the Registration Statement.


 




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b.
Promptly after receipt by an Indemnified Person or Indemnified Party under this Section 6 of notice of the commencement of any
action or proceeding (including any governmental action or proceeding) involving a Claim, such Indemnified Person or Indemnified Party
shall, if a Claim in respect thereof is to be made against any indemnifying party under this Section 6, deliver to the indemnifying
party a written notice of the commencement thereof, and the indemnifying party shall have the right to participate in, and, to the extent
the indemnifying party so desires, jointly with any other indemnifying party similarly noticed, to assume control of the defense thereof
with counsel mutually satisfactory to the indemnifying party and the Indemnified Person or the Indemnified Party, as the case may be;
provided, however, that an Indemnified Person or Indemnified Party shall have the right to retain its own counsel with the fees and expenses
to be paid by the indemnifying party, if, in the reasonable opinion of counsel retained by the indemnifying party, the representation
by such counsel of the Indemnified Person or Indemnified Party and the indemnifying party would be inappropriate due to actual or potential
differing interests between such Indemnified Person or Indemnified Party and any other party represented by such counsel in such proceeding.
The indemnifying party shall pay for only one separate legal counsel for the Indemnified Persons or the Indemnified Parties, as applicable.
Such counsel shall be selected by the Company if the Company is the indemnifying party. The Indemnified Party or Indemnified Person shall
cooperate fully with the indemnifying party in connection with any negotiation or defense of any such action or claim by the indemnifying
party and shall furnish to the indemnifying party all information reasonably available to the Indemnified Party or Indemnified Person
which relates to such action or claim. The indemnifying party shall keep the Indemnified Party or Indemnified Person fully apprised at
all times as to the status of the defense or any settlement negotiations with respect thereto. No indemnifying party shall be liable
for any settlement of any action, claim or proceeding effected without its written consent, provided, however, that the indemnifying
party shall not unreasonably withhold, delay or condition its consent. No indemnifying party shall, without the consent of the Indemnified
Party or Indemnified Person, consent to entry of any judgment or enter into any settlement or other compromise which does not include
as an unconditional term thereof the giving by the claimant or plaintiff to such Indemnified Party or Indemnified Person of a release
from all liability in respect to such Claim. Following indemnification as provided for hereunder, the indemnifying party shall be subrogated
to all rights of the Indemnified Party or Indemnified Person with respect to all third parties, firms or corporations relating to the
matter for which indemnification has been made. The failure to deliver written notice to the indemnifying party within a reasonable time
of the commencement of any such action shall not relieve such indemnifying party of any liability to the Indemnified Person or Indemnified
Party under this Section 6, except to the extent that the indemnifying party is actually prejudiced in its ability to defend such
action.


 


c.
The indemnification required by this Section 6 shall be made by periodic payments of the amount thereof during the course of the
investigation or defense, as and when bills are received or Indemnified Damages are incurred.


 


d.
The indemnity agreements contained herein shall be in addition to (i) any cause of action or similar right of the Indemnified Party or
Indemnified Person against the indemnifying party or others, and (ii) any liabilities the indemnifying party may be subject to pursuant
to the law.


 




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7.
Contribution.


 


To
the extent any indemnification by an indemnifying party is prohibited or limited by law, the indemnifying party agrees to make the maximum
contribution with respect to any amounts for which it would otherwise be liable under Section 6 hereof to the fullest extent permitted
by law; provided, however, that: (i) no contribution shall be made under circumstances where the maker would not have been liable for
indemnification under the fault standards set forth in Section 6 hereof; (ii) no seller of Piggy-Back Registrable Securities guilty
of fraudulent misrepresentation (within the meaning of Section 11(f) of the Securities Act) shall be entitled to contribution from any
seller of Piggy-Back Registrable Securities who was not guilty of fraudulent misrepresentation; and (iii) contribution by any seller
of Piggy-Back Registrable Securities shall be limited in amount to the net amount of proceeds received by such seller from the sale of
such Piggy-Back Registrable Securities.


 


8.
Reports Under The Exchange Act.


 


With
a view to making available to the Holder the benefits of Rule 144 under the Securities Act or any similar rule or regulation of the SEC
that may at any time permit the Investors to sell securities of the Company to the public without registration (“Rule 144”)
the Company agrees to take commercially reasonable efforts to:


 


a.
make and keep public information available, as those terms are understood and defined in Rule 144;


 


b.
file with the SEC in a timely manner all reports and other documents required of the Company under the Securities Act and the Exchange
Act so long as the Company remains subject to such requirements and the filing of such reports and other documents as are required by
the applicable provisions of Rule 144; and


 


c.
furnish to the Holder so long as the Holder owns Piggy-Back Registrable Securities, promptly upon request, (i) a written statement by
the Company that it has complied with the reporting requirements of Rule 144, the Securities Act and the Exchange Act, (ii) a copy of
the most recent annual or quarterly report of the Company and such other reports and documents so filed by the Company, and (iii) such
other information as may be reasonably requested to permit the Investors to sell such securities pursuant to Rule 144 without registration.


 


9.
No Assignment Of Registration Rights.


 


The
registration rights and obligations under this Agreement shall not be assignable.


 


10.
Amendment Of Registration Rights.


 


Provisions
of this Agreement may be amended and the observance thereof may be waived (either generally or in a particular instance and either retroactively
or prospectively), only with the written consent of both the Company and the Holder of the Piggy-Back Registrable Securities. Any amendment
or waiver effected in accordance with this Section 10 shall be binding upon the Holder and the Company.


 


11.
Miscellaneous.


 


a.
Any notices, consents, waivers or other communications required or permitted to be given under the terms of this Agreement must be in
writing and will be deemed to have been delivered (i) upon receipt, when delivered personally; (ii) upon receipt, when sent by facsimile
(provided a confirmation of transmission is mechanically or electronically generated and kept on file by the sending Party); or (iii)
one (1) day after deposit with a nationally recognized overnight delivery service, in each case properly addressed to the Party to receive
the same. The addresses for such communications are as set forth on the signature page to this Agreement. Each Party shall provide five
(5) business days prior notice to the other Party of any change in address, phone number or facsimile number.


 


b.
Failure of any Party to exercise any right or remedy under this Agreement or otherwise, or delay by a Party in exercising such right
or remedy, shall not operate as a waiver thereof.


 


c.
This Agreement and all acts and transactions pursuant hereto and the rights and obligations of the Parties hereto shall be governed,
construed and interpreted in accordance with the laws of the State of Delaware, without giving effect to principles of conflicts of law.
The Parties submit to the jurisdiction of the state of New York and federal courts in the borough of Manhattan, New York, and agree that
any legal action or proceeding relating to this Agreement may be brought in those courts.


 




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d.
This Agreement and the Securities Purchase Agreement, Note, Warrant, and any other documents entered into between in connection with
the aforementioned documents constitute the entire set of agreements among the Parties hereto with respect to the subject matter hereof
and thereof.


 


e.
[Intentionally Omitted].


 


f.
The headings in this Agreement are for convenience of reference only and shall not limit or otherwise affect the meaning hereof.


 


g.
This Agreement may be executed in two or more counterparts, all of which taken together shall constitute one instrument. Execution and
delivery of this Agreement by exchange of facsimile copies bearing the facsimile signature of a Party shall constitute a valid and binding
execution and delivery of this Agreement by such Party. Such facsimile copies shall constitute enforceable original documents.


 


h.
Each Party shall do and perform, or cause to be done and performed, all such further acts and things, and shall execute and deliver all
such other agreements, certificates, instruments and documents, as the other Party may reasonably request in order to carry out the intent
and accomplish the purposes of this Agreement and the consummation of the transactions contemplated hereby.


 


i.
All consents and other determinations to be made by the Holder pursuant to this Agreement shall be made, unless otherwise specified in
this Agreement, by the Holder holding a majority of the Piggy-Back Registrable Securities.


 


j.
The language used in this Agreement will be deemed to be the language chosen by the Parties to express their mutual intent and no rules
of strict construction will be applied against any Party.


 


k.
The Company hereby represents to the Holder that: (i) it has voluntarily entered into this Agreement of its own freewill, (ii) it is
not entering into this Agreement under economic duress, (iii) the terms of this Agreement are reasonable and fair to the Company, and
(iv) the Company has had independent legal counsel of its own choosing review this Agreement, advise the Company with respect to this
Agreement, and represent the Company in connection with its entering into this Agreement.


 


l.
Notwithstanding anything in this Agreement to the contrary, the Parties hereto hereby acknowledge and agree to the following: (i) the
Holder makes no representations or covenants that it will not engage in trading in the securities of the Company; (ii) the Company has
not and shall not provide material non-public information to the Holder unless prior thereto the Holder shall have executed a written
agreement regarding the confidentiality and use of such information; and (iii) the Company understands and confirms that the Holder will
be relying on the acknowledgements set forth in clauses (i) through (iii) above if the Holder effects any transactions in the securities
of the Company.


 


12.
Waiver.


 


The
Holder’s delay or failure at any time or times hereafter to require strict performance by Company of any undertakings, agreements
or covenants shall not waive, affect, or diminish any right of the Holder under this Agreement to demand strict compliance and performance
herewith. Any waiver by the Holder of any breach under this Agreement (a “RRA Breach”) shall not waive or affect any
other RRA Breach, whether such RRA Breach is prior or subsequent thereto and whether of the same or a different type. None of the undertakings,
agreements and covenants of the Company contained in this Agreement, and no RRA Breach, shall be deemed to have been waived by the Holder,
nor may this Agreement be amended, changed or modified, unless such waiver, amendment, change or modification is evidenced by an instrument
in writing specifying such waiver, amendment, change or modification and signed by the Holder.


 


13.
Payment Of Liquidated Damages.


 


With
respect to any liquidated damages or other fees incurred herein by the Company for failure to act in a timely manner, the Holder reserves
the rights to take payment of such amounts in cash or in Common Stock priced at the Conversion Price (as defined in the Note).


 


[Signature
Page Follows]


 




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IN
WITNESS WHEREOF, the Parties hereto have caused this Registration Rights Agreement to be duly executed on the day and year first
above written.


 


	 	THE
    COMPANY:
	 	 
	 	RESPIRERX
    PHARMACEUTICALS INC.
	 	 	                          
	 	By:
    	/s/
Jeff Eliot Margolis
	 	Name:	Jeff
    Margolis 
	 	Title:
    	Senior
    Vice President, Chief Financial Officer, Treasurer and Secretary
	 	Address:
    	126
    Valley Road, Suite C
	 	 	Glen
    Rock, New Jersey 07452
	 	 	 
	 	HOLDER:
	 	 
	 	BARTON
    ASSET MANAGMENT 
	 	(entity
    name, if applicable)
	 	 	 
	 	By:
    	/s/
    Harris Barton
	 	Name:	Harris
Barton
	 	Title:
    	Managing
    Member
	 	Address:
    	135
    Main Street, Suite 850
	 	 	San
    Francisco, CA 94105


 


[End
of Exhibit B]


 




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