Exhibit 4.1

      

      

      DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED

      PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934

       

      General

       

      As of the end of the period covered by the most recent Annual Report on Form 10-K of Brooklyn ImmunoTherapeutics, Inc. (the “registrant”), the common stock, par value $0.005 per share, of the registrant (“common stock”) was registered under Section 12 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). Unless the context
        otherwise requires, all references herein to “we,” “our,” “ours,” “Company” and “us” refer to Brooklyn ImmunoTherapeutics, Inc.

       

      The following description of the common stock is a summary and does not purport to be complete and is qualified in its entirety by reference to
        the terms and provisions contained in our restated certificate of incorporation, including the amendments thereto, which we refer to as our certificate of incorporation, and our amended and restated bylaws, which we refer to as our bylaws, which
        are incorporated by reference as exhibits to our most recently filed Annual Report on Form 10-K, of which this exhibit forms a part.

       

      Our common stock and the rights of the holders of our common stock are subject to the applicable provisions of the General Corporation Law of the
        State of Delaware, which we refer to as the DGCL, our certificate of incorporation and our bylaws. The description below of our common stock and provisions of our certificate of incorporation and our bylaws are summaries and are qualified by
        reference to our certificate of incorporation and our bylaws, as applicable, and by the applicable provisions of the DGCL. We encourage you to read that law and those documents carefully.

       

      
        Common Stock

      

      
        

        

        Our authorized capital stock consists of 100,000,000 shares of common stock, par value $0.005 per share, and 1,000,000 shares of preferred
          stock, par value $0.005 per share (the “preferred stock”). A total of 156,112 shares of preferred stock have been designated as Series A Convertible Preferred Stock. As of April 12, 2022, 51,951,937 shares of common stock were outstanding and
          156,112 shares of Series A Convertible Preferred Stock were outstanding.

      

      
        

        

      

      
        Voting Rights

        

        

        Each holder of common stock is entitled to one vote for each share on all matters submitted to a vote of the stockholders, including the
          election of directors. Votes may be cast in person or by proxy. Stockholders do not have cumulative voting rights with respect to election of directors.

        

        

        Dividends

        

        

        The holders of Series A convertible preferred stock are entitled to receive cumulative dividends of $0.10 per share per annum, payable
          semiannually in equal installments of $0.05 per share on June 1 and December 1 of each year. After the requirements with respect to the preferential dividends of the preferred stock have been met, holders of common stock are entitled to receive
          proportionately any dividends as may be declared and paid on common stock from funds lawfully available therefor as and when determined by the board of directors, subject to any preferential dividend rights of outstanding preferred stock.

        

        

        Liquidation and Dissolution

        

        

        In the event of our liquidation or dissolution, the holders of common stock are entitled to receive proportionately all assets available for
          distribution to stockholders after the payment of all debts and other liabilities and subject to the prior rights of any outstanding preferred stock.

        

        

        Other Rights

        

        

        Holders of common stock have no preemptive, subscription, redemption or
            conversion rights and there are no sinking fund provisions with respect to our common stock. The rights, preferences and privileges of holders of common stock are subject to and may be adversely affected by the rights of the holders of shares
            of any series of preferred stock. All of the shares of the common stock currently issued and outstanding are fully-paid and nonassessable.

        

        

      

      
        
          


      

      
        Provisions of Our Certificate of Incorporation and Bylaws and Delaware General Corporation Law may have Anti-Takeover Effects

        

        

      

      
        Our certificate of incorporation and bylaws and the DGCL contain provisions that could have the effect of delaying, deferring or discouraging
          another party from acquiring control of us. These provisions, which are summarized below, are expected to discourage coercive takeover practices and inadequate takeover bids and are designed in part to encourage persons seeking to acquire control
          of us to first negotiate with the board of directors.

        

        

      

      
        Number of Directors; Vacancies

        

        

      

      
        Our certificate of incorporation provides that the number of directors is established by the board of directors, which may delay the ability of
          stockholders to change the composition of a majority of the board. The board has the exclusive right to elect a director to fill any vacancy or newly created directorship.

        

        

      

      
        Removal of Directors

        

        

      

      
        A director may be removed only by the affirmative vote of the holders of at least 80% of the voting power of all shares entitled to vote
          generally in the election of directors, voting together as a single class.

        

        

      

      
        Stockholder Action by Written Consent; Special Meetings

        

        

      

      
        Our certificate of incorporation provides that any action required or permitted to be taken by our stockholders must be effected at a duly
          called annual or special meeting of such holders and may not be effected by any consent in writing by such holders. Our certificate of incorporation and bylaws also provide that, except as otherwise required by law, special meetings of our
          stockholders can only be called by the board of directors. These provisions may delay the ability of our stockholders to force consideration of a proposal or to take action, including the removal of directors.

        

        

      

      
        Advance Notice Requirements for Stockholder Proposals

        

        

      

      
        Our bylaws establish an advance notice procedure for stockholder proposals to be brought before an annual meeting of stockholders, including
          proposed nominations of persons for election to the board of directors. Stockholders at an annual meeting may consider proposals or nominations specified in the notice of meeting or brought before the meeting by or at the direction of the board
          or by a stockholder of record on the record date for the meeting who is entitled to vote at the meeting and who has delivered timely written notice in proper form to our secretary of the stockholder’s intention to bring such business before the
          meeting. These provisions could have the effect of delaying until the next stockholder meeting stockholder actions that are favored by the holders of a majority of our outstanding voting securities.

        

        

      

      
        Delaware Business Combination Statute

        

        

      

      
        We are a Delaware corporation subject to Section 203 of the DGCL. Under Section 203, certain “business combinations” between a Delaware
          corporation whose stock is listed on a national securities exchange or held of record by more than 2,000 stockholders and an “interested stockholder” are prohibited for a three-year period following the date that such stockholder became an
          interested stockholder, unless:

        

        

      

      
        	

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                 the corporation has elected in its certificate of incorporation not to be governed by Section 203;

              


      

      
        

        

      

      
        	

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                the business combination or the transaction which resulted in the stockholder becoming an interested stockholder was approved by the board of directors of the corporation before the date of
                  the business combination or the date such stockholder became an interested stockholder, as applicable;

              


      

      

      

      
        
          


      

      
        	

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                upon consummation of the transaction that made such stockholder an interested stockholder, the interested stockholder owned at least 85% of the “voting stock” (as defined in Section 203) of
                  the corporation outstanding at the commencement of the transaction excluding voting stock owned by directors who are also officers or held in employee benefit plans in which the employees do not have a confidential right to tender stock
                  held by the plan in a tender or exchange offer; or

              


      

      
        

        

      

      
        	

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                the business combination is approved by the board of directors and by the stockholders (acting at a meeting and not by written consent) by the affirmative vote of at least 66-2/3% of the
                  outstanding voting stock which is not “owned” (as defined in Section 203) by the interested stockholder.

              


      

      
        

        

        The three-year prohibition also does not apply to some business combinations proposed by an interested stockholder following the announcement or
          notification of an extraordinary transaction involving the corporation and a person who had not been an interested stockholder during the previous three years or who became an interested stockholder with the approval of a majority of the
          corporation’s directors. The term “business combination” is defined generally to include mergers or consolidations between a Delaware corporation and an interested stockholder, transactions with an interested stockholder involving the assets or
          stock of the corporation or its majority-owned subsidiaries and transactions which increase an interested stockholder’s percentage ownership of stock, or other transaction resulting in a financial benefit to the interested stockholder. The term
          “interested stockholder” is defined generally as those stockholders who become beneficial owners of 15% or more of a Delaware corporation’s voting stock, together with the affiliates or associates of that stockholder.

        

        

      

      
        Certificate of Incorporation or Bylaws

        

        

      

      
        Any provision of our certificate of incorporation may be amended, altered, changed or repealed in any manner prescribed by law; provided, that
          (a) the affirmative vote of the holders of at least 80% of the voting power of all shares entitled to vote generally in the election of directors, voting together as a single class, is required to alter, amend, or repeal, or adopt any provision
          inconsistent with Article X of the certificate of incorporation, which contains the prohibition on stockholder action by written consent and the requirement that special meetings be called only by the board of directors, and (b) Article XI of the
          certificate of incorporation, provides that, subject to certain exceptions, no purchase by or from any Controlling Person (as defined below) of shares of our stock owned by such Controlling Person shall be made at a price exceeding the average
          price paid by such Controlling Person for all shares of our stock acquired by such Controlling Person during the two-year period preceding the date of such proposed purchase unless such purchase is approved by the affirmative vote of not less
          than a majority of the voting power of the shares of our stock entitled to vote held by Disinterested Stockholders (as defined below), may not be amended without the affirmative vote of not less than a majority of the our stock entitled to vote
          thereon, provided that if, at the time of such vote, there shall be one or more Controlling Persons, such affirmative vote shall include the affirmative vote in favor of such amendment of not less than a majority of the voting power of the shares
          of our stock entitled to vote thereon held by Disinterested Stockholders. “Controlling Person” means any individual, corporation, partnership, trust, association or other organization or entity (including any group formed for the purpose of
          acquiring, voting or holding our securities) which either directly, or indirectly through one or more intermediaries, owns, beneficially or of record, or controls by agreement, voting trust or otherwise, at least 10% of the voting power of stock,
          and such term also includes any corporation, partnership, trust, association or other organization or entity in which one or more Controlling Persons have the power, through the ownership of voting securities, by contract, or otherwise, to
          influence significantly any of the management, activities or policies of such corporation, partnership, trust, association, other organization or entity. “Disinterested Stockholders” means those holders of stock entitled to vote on any matter,
          none of which is a Controlling Person.

        

        

      

      
        The board may, by majority vote, amend or repeal our bylaws and may adopt new bylaws.

        

        

      

      
        Our stockholders may not adopt, amend, or repeal our bylaws or adopt new bylaws except by the vote or written consent of at least 66-2/3% of the
          voting power of our company.

         

      

      
        
          


      

      
        Exclusive Forum Selection

        

        

      

      
        Our bylaws provide that, unless we consent in writing to the selection of an alternative forum, the a state court located in the State of
          Delaware (or if no state court has jurisdiction, the federal district court for the District of Delaware) shall be the sole and exclusive forum for (a) any derivative action or proceeding brought on our behalf, (b) any action asserting a claim of
          breach of a fiduciary duty owed by any of our directors or officers to our company or stockholders, (c) any action asserting a claim against us arising pursuant to any provision of the Delaware General Corporation Law or our certificate of
          incorporation or amended and restated bylaws, or (d) any action asserting a claim against us governed by the internal affairs doctrine. Although our bylaws contain the choice of forum provision described above, it is possible that a court could
          rule that such a provision is inapplicable for a particular claim or action or that such provision is unenforceable.

        

        

      

      
        Authorized but Unissued Shares

        

        

      

      
        Our authorized but unissued shares of common stock and preferred stock are available for future issuance without stockholder approval, subject
          to any limitations imposed by the listing requirements of The Nasdaq Global Market. These additional shares may be used for a variety of corporate finance transactions, acquisitions and employee benefit plans. The existence of authorized but
          unissued and unreserved common stock and preferred stock could make it more difficult or discourage an attempt to obtain control of us by means of a proxy contest, tender offer, merger or otherwise.

        

        

      

      
        Listing on The Nasdaq Global Market

        

        

        The common stock is listed on The Nasdaq Global Market under the symbol “BTX.”

        

        

        Transfer Agent and Registrar

        

        

      

      
        The transfer agent and registrar for the common stock is Computershare Trust Company, N.A.