SOYACYST LF

Biological control for use on soybean against soybean cyst nematode

WITH THE ALTERNATE BRAND NAME:

SOYACYST ST

Biological control for use on soybean seed against soybean cyst nematode

 

MASTER LABEL

SUB-LABEL A: FOR AGRICULTURAL USE AS FOLIAR TREATMENT AND 

SEED TREATMENT

SUB-LABEL B: FOR AGRICULTURAL USE AS FOLIAR TREATMENT

 

SUB-LABEL C: FOR SEED TREATMENT

 

Active Ingredient: Pasteuria nishizawae – Pn1* ........................................33.29%

Other Ingredients: ............................................... .. ....... .............................66.71% 

Total: ....................................................................... ............. ........................100.00% 

* Contains at least 1.3x107 spores per g or 5.9x109 spores per pound.

EPA Registration No: 85004-O

EPA Est. Number: 

 

Manufactured for:

12085 Research Dr., Suite 185

Alachua, FL 32615

(386) 462-0008

www.pasteuriabio.com/
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 2 of 29 December 20, 2011

SOYACYST LF

Biological control for use on soybean against soybean cyst nematode

WITH THE ALTERNATE BRAND NAME:

SOYACYST ST

Biological control for use on soybean seed against soybean cyst nematode

SUB-LABEL A

FOR AGRICULTURAL USE AS FOLIAR APPLICATION

AND SEED TREATMENT
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 3 of 29 December 20, 2011

SUB-LABEL A

SOYACYST LF

Biological control for use on soybean against soybean cyst nematode

WITH THE ALTERNATE BRAND NAME:

SOYACYST ST

Biological control for use on soybean seed against soybean cyst nematode

 

Active Ingredient: Pasteuria nishizawae – Pn1* ........................................33.29%

Other Ingredients: ............................................... .. ....... .............................66.71% 

Total: ....................................................................... ............. ........................100.00% * Contains at least 1.3x107

 spores per g or 5.9x109 spores per pound.

KEEP OUT OF REACH OF CHILDREN

CAUTION

See additional precautionary and first aid statements on the back panel

Net Contents: 2.5, 5, 10 gallons

EPA Registration No: 85004-O

EPA Est. Number: 

Manufactured for:

12085 Research Dr., Suite 185

Alachua, FL 32615

(386) 462-0008

www.pasteuriabio.com/
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 4 of 29 December 20, 2011

PRECAUTIONARY STATEMENTS

HAZARDS TO HUMANS AND DOMESTIC ANIMALS

CAUTION

Harmful if inhaled. Avoid breathing spray mist. Remove and wash contaminated 

clothing before reuse.

FIRST AID

If inhaled:

• Move person to fresh air.

• If person is not breathing, call 911 or an ambulance, then give 

artificial respiration, preferably mouth-to-mouth if possible.

• Call a poison control center or doctor for treatment advice.

HOT LINE NUMBER

Have the product container or label with you when calling a poison control center or 

doctor, or going for treatment. For emergency information concerning this product, 

call the National Pesticide Information Center (NPIC) at 1-800-858-7378 seven days 

a week, 6:30 am to 4:30 pm Pacific Time. During other times, call your poison 

control center at 1-800-222-1222.

PERSONAL PROTECTIVE EQUIPMENT (PPE)

Applicators and other handlers must wear:

• Long-sleeved shirt and long pants

• Shoes plus socks

Mixers/loaders and applicators must wear a dust/mist filtering respirator meeting 

NIOSH standards of at least N-95, R-95, or P-95. Repeated exposure to high 

concentrations of microbial proteins can cause allergic sensitization.

Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such 

instructions are available, use detergent and hot water for washables. Keep and wash 

PPE separately from other laundry.
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 5 of 29 December 20, 2011

USER SAFETY RECOMMENDATIONS

Users should:

 • Wash hands before eating, drinking, chewing gum, using tobacco or using the 

toilet. 

 • Remove clothing/PPE immediately if pesticide gets inside. Then wash 

thoroughly and put on clean clothing.

 • Remove PPE immediately after handling this product. As soon as possible, 

wash thoroughly and change into clean clothing.

ENVIRONMENTAL HAZARDS 

[Containers with capacities of 5 gallons or less:] For terrestrial uses, do not apply 

directly to water, or to areas where surface water is present or to intertidal areas 

below the mean high water mark.

Do not contaminate water when disposing of equipment wash waters or rinsate.

[Containers with capacities greater than 5 gallons:] Do not discharge effluent 

containing this product into lakes, streams, ponds, estuaries, oceans, or other waters 

unless in accordance with the requirements of a National Pollutant Discharge 

Elimination System (NPDES) permit and the permitting authority has been notified 

in writing prior to discharge. Do not discharge effluent containing this product to 

sewer systems without previously notifying the local sewage treatment plant 

authority. For guidance, contact your State Water Board or Regional Office of EPA.

For terrestrial uses, do not apply directly to water, or to areas where surface water is 

present or to intertidal areas below the mean high water mark.

Do not contaminate water when disposing of equipment wash waters or rinsate.

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner inconsistent with 

its labeling.

Do not use this product until you have read the entire label. Do not apply this 

product in a way that will contact workers or other persons, either directly or through 

drift. Only protected handlers may be in the area during application. For any 

requirement specific to your State or Tribe, consult the State or Tribal agency 

responsible for pesticide regulation. 
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 6 of 29 December 20, 2011

AGRICULTURAL USE REQUIREMENTS

Use this product only in accordance with its labeling and with the Worker Protection 

Standard, 40 CFR Part 170. This Standard contains requirements for the protection 

of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 

agricultural pesticides. It contains requirements for training, decontamination, 

notification and emergency assistance. It also contains specific instructions and 

exceptions pertaining to the statements on this label about personal protective 

equipment (PPE) and restricted-entry interval. The requirements in this box apply 

only to the uses of this product that are covered by the Worker Protection Standard.

Do not enter or allow worker entry into treated areas during the restricted-entry 

interval (REI) of 4 hours.

EXCEPTION: If the product is soil injected or soil incorporated, the Worker 

Protection Standard, under certain circumstances, allows workers to enter the treated 

area if there will be no contact with anything that has been treated.

PPE required for early entry to treated areas (that is permitted under the Worker 

Protection Standard and that involves contact with anything that has been treated,

such as plants, soil or water) is:

 • Water proof gloves

 • Coveralls

 • Shoes plus socks

NON- AGRICULTURAL USE REQUIREMENTS

The requirements in this box apply to uses of this product that are NOT within 

the scope of the Worker Protection Standard for agricultural pesticides (40 CFR 

Part 170). The WPS applies when this product is used to produce agricultural 

plants on farms, forests, nurseries or greenhouses.

Keep unprotected persons out of treatment areas until seeds have dried or been 

packaged.

PRODUCT INFORMATION

This product contains a biological nematicide for the control of the following 

nematode:

Soybean Cyst Nematode Heterodera glycines
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 7 of 29 December 20, 2011

FOR USE AS FOLIAR APPLICATION

APPLICATION INSTRUCTIONS

Soybean: Apply 1.3 to 64 fluid ounces (fl oz) of SOYACYST LF per 1000 square 

feet of soybean prior to planting and subsequently in 3 to 4 week intervals. Use the 

higher application rate on sites with high Soybean cyst nematode populations 

(greater than 50 Soybean cyst nematodes per 0.4 cup [100cm3] of soil) or areas with 

extensive nematode damage such as stunted plants, dying plants, or heavily stunted 

root systems compared to unaffected plants in the same field. For best control, a 

minimum of 3 sequential applications is required. Monthly applications throughout 

the year may help maintain Soybean cyst nematode populations below economic 

threshold levels.

SOYACYST LF may be diluted in water to attain proper distribution across the area

to be treated. This product may be applied using standard calibrated ground sprayapplication equipment and incorporated to a 4-inch depth prior to bed formation or 

applied via chemigation through the irrigation system after bed formation (preplanting). Agitation in the mix tank is recommended for any application requiring 

dilution of the formulated product with water prior to application. When mixing, fill 

the tank one-half full with water, add SOYACYST LF slowly to the tank with 

hydraulic or mechanical agitation, and continue to fill with water. For diluted 

product applications, apply product in the appropriate amount of water to treat the 

root-zone of the crop without flushing the product beyond the root-zone of the crop 

(this can vary with soil type and crop stage). 

Apply enough water following all applications to move the Pasteuria spores into the 

soybean root-zone and to flush the irrigation lines of any remaining product. After 

application of SOYACYST LF and subsequent treatment with water, minimizing 

irrigation for several weeks following treatment may improve Soybean cyst

nematode control. For areas under intense irrigation, repeat applications may be 

necessary to maintain Soybean cyst nematode populations below an economic 

threshold.

DAYS TO HARVEST

There are no restrictions on applying SOYACYST LF up to the time of harvest.
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 8 of 29 December 20, 2011

CHEMIGATION

Basic Requirements:

1) Apply this product only through sprinkler (including center pivot, lateral 

move, end tow, side (wheel) roll, traveler, big gun, solid set, or hand move) 

and drip (trickle) irrigation systems. Do not apply this product through any 

other type of irrigation system.

2) Crop injury or lack of effectiveness can result from non-uniform distribution 

of treated water.

3) If you have questions about calibration, you should contact State Extension 

Service specialists, equipment manufacturers, or other experts.

4) Do not connect an irrigation system (including greenhouse systems) used for 

pesticide application to a public water system unless the pesticide labelprescribed safety devices for public water systems are in place.

5) A person knowledgeable of the chemigation system and responsible for its 

operation, or under the supervision of the responsible person, shall shut the 

system down and make any necessary adjustments should the need arise.

Requirements for Chemigation Systems Connected to Public Water Systems:

1) Public water supply means a system for the provision to the public of piped 

water for human consumption if such system has at least 15 service 

connections or regularly serves an average of 25 individuals daily at least 60 

days throughout the year.

2) Chemigation systems connected to the public water systems must contain a 

functional, reduced-pressure zone (RPZ), backflow preventer or the 

functional equivalent in the water supply upstream from the point of pesticide 

introduction. As an option to the RPZ, the water from the public water system 

should be discharged into a reservoir tank prior to pesticide introduction. 

There shall be a complete physical break (air gap) between the flow outlet 

end of the fill pipe and the top or overflow rim of the reservoir tank of at least 

twice the inside diameter of the fill pipe.

3) The pesticide injection pipeline must contain a functional, automatic, quickclosing check valve to prevent the flow of fluid back toward the injection 

pump.

4) The pesticide injection pipeline must contain a functional, normally closed, 

solenoid-operated valve located on the intake side of the injection pump and 

connected to the system interlock to prevent fluid from being withdrawn from 

the supply tank when the irrigation system is either automatically or manually 

shut down.

5) The system must contain functional interlocking controls to automatically 

shut off the pesticide injection pump when the water pump motor stops, or in 

cases where there is no water pump, when the water pressure decreases to the 

point where pesticide distribution is adversely affected.

6) Systems must use a metering pump, such as a positive displacement injection 

pump (e.g., diaphragm pump), effectively designed and constructed of 
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 9 of 29 December 20, 2011

materials that are compatible with pesticides and capable of being fitted with 

a system interlock.

7) Do not apply when wind speed favors drift beyond the area intended for 

treatment.

Requirements for Sprinkler Chemigation:

1) The system must contain a functional check valve, vacuum relief valve, and 

low pressure drain appropriately located on the irrigation pipeline to prevent 

water source contamination from back flow.

2) The pesticide injection pipeline must contain a functional, automatic, quickclosing check valve to prevent the flow of fluid back toward the injection 

pump.

3) The pesticide injection pipeline must also contain a functional, normally 

closed, solenoid-operated valve located on the intake side of the injection 

pump and connected to the system interlock to prevent fluid from being 

withdrawn from the supply tank when the irrigation system is either 

automatically or manually shut down.

4) The system must contain functional interlocking controls to automatically 

shut off the pesticide injection pump when the water pump motor stops.

5) The irrigation line or water pump must include a functional pressure switch,

which will stop the water pump motor when the water pressure decreases to 

the point where pesticide distribution is adversely affected.

6) Systems must use a metering pump, such as a positive displacement injection 

pump (e.g., diaphragm pump), effectively designed and constructed of 

materials that are compatible with pesticides and capable of being fitted with 

a system interlock.

7) Do not apply when wind speed favors drift beyond the area intended for 

treatment.

Requirements for Drip Chemigation:

 1) The system must contain a functional check valve, vacuum relief valve and

 low pressure drain appropriately located on the irrigation pipeline to prevent 

water source contamination from back flow.

2) The pesticide injection pipeline must contain a functional, automatic, quickclosing check valve to prevent the flow of fluid back toward the injection 

pump.

3) The pesticide injection pipeline must also contain a functional, normally 

closed, solenoid-operated valve located on the intake side of the injection 

pump and connected to the system interlock to prevent fluid from being 

withdrawn from the supply tank when the irrigation system is either 

automatically or manually shut down.

4) The system must contain functional interlocking controls to automatically 

shut off the pesticide injection pump when the water pump motor stops.

5) The irrigation line or water pump must include a functional pressure switch,

which will stop the water pump motor when the water pressure decreases to 

the point where pesticide distribution is adversely affected.
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 10 of 29 December 20, 2011

6) Systems must use a metering pump, such as a positive displacement injection

pump (e.g., diaphragm pump), effectively designed and constructed of

materials that are compatible with pesticides and capable of being fitted with

a system interlock.

FOR USE AS A SEED TREATMENT

Treatment of highly mechanically scarred or damaged seed, or seed known to be of 

low vigor and poor quality, except for the purpose of curative control of existing 

disease pests, may result in reduced germination and/or reduction of seed and 

seedling vigor. Treat a small quantity of seed using equipment similar to that 

planned for treating the total seed lot. Conduct germination tests on a small portion 

of seed before committing the total seed lot to a selected seed treatment. Due to seed 

quality, crop or variety sensitivity, and seed storage conditions beyond the control of 

manufacturer, no claims are made to guarantee the germination of carry-over seed or 

propagating material for all crop seed.

FOR USE AS A PRE-PLANT SEED TREATMENT

Treat only those seeds needed for immediate use, minimizing the interval between 

treatment and planting. Do not store excess treated seeds beyond planting time.

To achieve improved application coverage to the seed, dilute SOYACYST LF with 

water and apply directly to dry seed or mix with inoculants and/or other registered 

seed treatment coatings (e.g., colorants, polymers, etc.), insecticides and fungicides. 

Do not mix SOYACYST LF with any product containing a label prohibition against 

such mixing. When tank-mixing with any other registered seed treatment insecticide 

and/or fungicide, always read and follow all use directions, restrictions, and 

precautions of both SOYACYST LF and the tank mix partner(s). The resulting tank 

mix must be in accordance with the more restrictive label limitations and 

precautions. Do not exceed label dosage rates. Please consult Pasteuria Bioscience, 

Inc. for additional information (http://www.pasteuriabio.com/).

SOYBEAN

For control of soybean cyst nematode, apply 2 to 5 fluid ounces of SOYACYST LF 

per 100 Lbs (60-150 mL per 45.4 kg) of soybean seed.

FOR USE AS A COMMERICAL SEED TREATMENT

To achieve improved application coverage to the seed, dilute SOYACYST LF with 

water and apply directly to dry seed or mix with inoculants and/or other registered 

seed treatment coating (e.g., colorants, polymers, etc.), insecticides and fungicides. 

Do not mix SOYACYST LF with any product containing a label prohibition against 

such mixing. When tank-mixing with any other registered seed treatment insecticide 
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 11 of 29 December 20, 2011

and/or fungicide, always read and follow all use directions, restrictions, and 

precautions of both SOYACYST LF and the tank mix partner(s). The resulting tank 

mix must be in accordance with the more restrictive label limitations and 

precautions. Do not exceed label dosage rates. Please consult Pasteuria Bioscience, 

Inc. for additional information (http://www.pasteuriabio. com/).

SOYBEAN 

For control of soybean cyst nematode, apply 2 to 5 fluid ounces of SOYACYST LF

per 100 Lbs (60–150 mL per 45.4 kg) of soybean seed. 

STORAGE AND DISPOSAL

Do not contaminate water, food, or feed by storage and disposal.

PESTICIDE STORAGE

Store refrigerated (~4oC). Reclose container of unused portions of SOYACYST LF.

PESTICIDE DISPOSAL

To avoid wastes, use all material in this container by application according to label 

directions. If wastes cannot be avoided, offer remaining product to a waste disposal 

facility or pesticide disposal program (often such programs are run by state or local 

governments or by industry).

CONTAINER HANDLING

[Plastic containers with capacities equal to or less than 5 gallons:] Nonrefillable 

container. Do not reuse or refill this container. Triple rinse container (or equivalent) 

promptly after emptying. Triple rinse as follows: Empty the remaining contents into 

application equipment or a mix tank and drain for 10 seconds after the flow begins to 

drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour 

rinsate into application equipment or a mix tank, or store rinsate for later use or 

disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure 

two more times. Then offer for recycling if available or puncture and dispose of in a 

sanitary landfill, or by incineration. Do not burn, unless allowed by state and local 

ordinance. If burned, stay out of smoke. 

[Plastic containers with capacities greater than 5 gallons:] Nonrefillable container. 

Do not reuse or refill this container. Triple rinse container (or equivalent) promptly 

after emptying. Triple rinse as follows: Empty the remaining contents into 

application equipment or a mix tank. Fill the container 1/4 full with water. Replace 

and tighten closures. Tip container on its side and roll it back and forth, ensuring at 

least one complete revolution, for 30 seconds. Stand the container on its end and tip 

it back and forth several times. Turn the container over onto its other end and tip it 

back and forth several times. Empty the rinsate into application equipment or a mix 

tank, or store rinsate for later use or disposal. Repeat this procedure two more times. 

Then offer for recycling if available or puncture and dispose of in a sanitary landfill, 
Proposed Label for SOYACYST LF / ST

Sub-Label A

Pasteuria Bioscience, Inc. 12 of 29 December 20, 2011

or by incineration. Do not burn, unless allowed by state and local ordinance. If 

burned, stay out of smoke.

WARRANTY STATEMENT

Pasteuria Bioscience, Inc. (PBI) warrants that this product conforms to its label 

description and is suitable for its intended use if stored and used in accordance with 

the Directions for Use. To the extent consistent with applicable law, PBI makes no 

warranty, express or implied, of merchantability, fitness or otherwise concerning the 

use of this product other than as indicated on this label. To the extent consistent with 

applicable law, user assumes all risks of use, storage or handling not in accordance 

with accompanying directions.
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 13 of 29 December 20, 2011

SOYACYST LF

Biological control for use on soybean against soybean cyst nematode

SUB-LABEL B

FOR AGRICULTURAL USE AS FOLIAR APPLICATION
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 14 of 29 December 20, 2011

SUB-LABEL B

SOYACYST LF

Biological control for use on soybean against soybean cyst nematode

 

Active Ingredient: Pasteuria nishizawae – Pn1* ........................................33.29%

Other Ingredients: ............................................... .. ....... .............................66.71% 

Total: ....................................................................... ............. ........................100.00% 

* Contains at least 1.3x107 spores per g or 5.9x109 spores per pound.

KEEP OUT OF REACH OF CHILDREN

CAUTION

See additional precautionary and first aid statements on the back panel

Net Contents: 2.5, 5, 10 gallons

EPA Registration No: 85004-O

EPA Est. Number: 

Manufactured for:

12085 Research Dr., Suite 185

Alachua, FL 32615

(386) 462-0008

www.pasteuriabio.com/
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 15 of 29 December 20, 2011

PRECAUTIONARY STATEMENTS

HAZARDS TO HUMANS AND DOMESTIC ANIMALS

CAUTION

Harmful if inhaled. Avoid breathing spray mist. Remove and wash contaminated 

clothing before reuse.

FIRST AID

If inhaled:

• Move person to fresh air.

• If person is not breathing, call 911 or an ambulance, then give 

artificial respiration, preferably mouth-to-mouth if possible.

• Call a poison control center or doctor for treatment advice.

HOT LINE NUMBER

Have the product container or label with you when calling a poison control center or 

doctor, or going for treatment. For emergency information concerning this product, 

call the National Pesticide Information Center (NPIC) at 1-800-858-7378 seven days 

a week, 6:30 am to 4:30 pm Pacific Time. During other times, call your poison 

control center at 1-800-222-1222.

PERSONAL PROTECTIVE EQUIPMENT (PPE)

Applicators and other handlers must wear:

• Long-sleeved shirt and long pants

• Shoes plus socks

Mixers/loaders and applicators must wear a dust/mist filtering respirator meeting 

NIOSH standards of at least N-95, R-95, or P-95. Repeated exposure to high 

concentrations of microbial proteins can cause allergic sensitization.

Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such 

instructions are available, use detergent and hot water for washables. Keep and wash 

PPE separately from other laundry.

USER SAFETY RECOMMENDATIONS

Users should:

 • Wash hands before eating, drinking, chewing gum, using tobacco or using the 

toilet. 

 • Remove clothing/PPE immediately if pesticide gets inside. Then wash 

thoroughly and put on clean clothing.

 • Remove PPE immediately after handling this product. As soon as possible, 

wash thoroughly and change into clean clothing.
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 16 of 29 December 20, 2011

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to 

intertidal areas below the mean high water mark.

Do not contaminate water when disposing of equipment wash waters or rinsate.

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner inconsistent with 

its labeling.

Do not use this product until you have read the entire label. Do not apply this 

product in a way that will contact workers or other persons, either directly or through 

drift. Only protected handlers may be in the area during application. For any 

requirement specific to your State or Tribe, consult the State or Tribal agency 

responsible for pesticide regulation. 

AGRICULTURAL USE REQUIREMENTS

Use this product only in accordance with its labeling and with the Worker Protection 

Standard, 40 CFR Part 170. This Standard contains requirements for the protection 

of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 

agricultural pesticides. It contains requirements for training, decontamination, 

notification and emergency assistance. It also contains specific instructions and 

exceptions pertaining to the statements on this label about personal protective 

equipment (PPE) and restricted-entry interval. The requirements in this box apply 

only to the uses of this product that are covered by the Worker Protection Standard.

Do not enter or allow worker entry into treated areas during the restricted-entry 

interval (REI) of 4 hours.

EXCEPTION: If the product is soil injected or soil incorporated, the Worker 

Protection Standard, under certain circumstances, allows workers to enter the treated 

area if there will be no contact with anything that has been treated.

PPE required for early entry to treated areas (that is permitted under the Worker 

Protection Standard and that involves contact with anything that has been treated,

such as plants, soil or water) is:

 • Water proof gloves

 • Coveralls

 • Shoes plus socks
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 17 of 29 December 20, 2011

PRODUCT INFORMATION

This product contains a biological nematicide for the control of the following 

nematode:

Soybean Cyst Nematode Heterodera glycines

APPLICATION INSTRUCTIONS

Soybean: Apply 1.3 to 64 fluid ounces (fl oz) of SOYACYST LF per 1000 square 

feet of soybean prior to planting and subsequently in 3 to 4 week intervals. Use the 

higher application rate on sites with high Soybean cyst nematode populations 

(greater than 50 Soybean cyst nematodes per 0.4 cup [100cm3] of soil) or areas with 

extensive nematode damage such as stunted plants, dying plants, or heavily stunted 

root systems compared to unaffected plants in the same field. For best control, a 

minimum of 3 sequential applications is required. Monthly applications throughout 

the year may help maintain Soybean cyst nematode populations below economic 

threshold levels.

SOYACYST LF may be diluted in water to attain proper distribution across the area

to be treated. This product may be applied using standard calibrated ground sprayapplication equipment and incorporated to a 4-inch depth prior to bed formation or 

applied via chemigation through the irrigation system after bed formation (preplanting). Agitation in the mix tank is recommended for any application requiring 

dilution of the formulated product with water prior to application. When mixing, fill 

the tank one-half full with water, add SOYACYST LF slowly to the tank with 

hydraulic or mechanical agitation, and continue to fill with water. For diluted 

product applications, apply product in the appropriate amount of water to treat the 

root-zone of the crop without flushing the product beyond the root-zone of the crop 

(this can vary with soil type and crop stage). 

Apply enough water following all applications to move the Pasteuria spores into the 

soybean root-zone and to flush the irrigation lines of any remaining product. After 

application of SOYACYST LF and subsequent treatment with water, minimizing 

irrigation for several weeks following treatment may improve Soybean cyst

nematode control. For areas under intense irrigation, repeat applications may be 

necessary to maintain Soybean cyst nematode populations below an economic 

threshold.

DAYS TO HARVEST

There are no restrictions on applying SOYACYST LF up to the time of harvest.
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 18 of 29 December 20, 2011

CHEMIGATION

Basic Requirements:

1) Apply this product only through sprinkler (including center pivot, lateral 

move, end tow, side (wheel) roll, traveler, big gun, solid set, or hand move) 

and drip (trickle) irrigation systems. Do not apply this product through any 

other type of irrigation system.

2) Crop injury or lack of effectiveness can result from non-uniform distribution 

of treated water.

3) If you have questions about calibration, you should contact State Extension 

Service specialists, equipment manufacturers, or other experts.

4) Do not connect an irrigation system (including greenhouse systems) used for 

pesticide application to a public water system unless the pesticide labelprescribed safety devices for public water systems are in place.

5) A person knowledgeable of the chemigation system and responsible for its 

operation, or under the supervision of the responsible person, shall shut the 

system down and make any necessary adjustments should the need arise.

Requirements for Chemigation Systems Connected to Public Water Systems:

1) Public water supply means a system for the provision to the public of piped 

water for human consumption if such system has at least 15 service 

connections or regularly serves an average of 25 individuals daily at least 60 

days throughout the year.

2) Chemigation systems connected to the public water systems must contain a 

functional, reduced-pressure zone (RPZ), backflow preventer or the 

functional equivalent in the water supply upstream from the point of pesticide 

introduction. As an option to the RPZ, the water from the public water system 

should be discharged into a reservoir tank prior to pesticide introduction. 

There shall be a complete physical break (air gap) between the flow outlet 

end of the fill pipe and the top or overflow rim of the reservoir tank of at least 

twice the inside diameter of the fill pipe.

3) The pesticide injection pipeline must contain a functional, automatic, quickclosing check valve to prevent the flow of fluid back toward the injection 

pump.

4) The pesticide injection pipeline must contain a functional, normally closed, 

solenoid-operated valve located on the intake side of the injection pump and 

connected to the system interlock to prevent fluid from being withdrawn from 

the supply tank when the irrigation system is either automatically or manually 

shut down.

5) The system must contain functional interlocking controls to automatically 

shut off the pesticide injection pump when the water pump motor stops, or in 

cases where there is no water pump, when the water pressure decreases to the 

point where pesticide distribution is adversely affected.

6) Systems must use a metering pump, such as a positive displacement injection 

pump (e.g., diaphragm pump), effectively designed and constructed of 
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 19 of 29 December 20, 2011

materials that are compatible with pesticides and capable of being fitted with 

a system interlock.

7) Do not apply when wind speed favors drift beyond the area intended for 

treatment.

Requirements for Sprinkler Chemigation:

1) The system must contain a functional check valve, vacuum relief valve, and 

low pressure drain appropriately located on the irrigation pipeline to prevent 

water source contamination from back flow.

2) The pesticide injection pipeline must contain a functional, automatic, quickclosing check valve to prevent the flow of fluid back toward the injection 

pump.

3) The pesticide injection pipeline must also contain a functional, normally 

closed, solenoid-operated valve located on the intake side of the injection 

pump and connected to the system interlock to prevent fluid from being 

withdrawn from the supply tank when the irrigation system is either 

automatically or manually shut down.

4) The system must contain functional interlocking controls to automatically 

shut off the pesticide injection pump when the water pump motor stops.

5) The irrigation line or water pump must include a functional pressure switch,

which will stop the water pump motor when the water pressure decreases to 

the point where pesticide distribution is adversely affected.

6) Systems must use a metering pump, such as a positive displacement injection 

pump (e.g., diaphragm pump), effectively designed and constructed of 

materials that are compatible with pesticides and capable of being fitted with 

a system interlock.

7) Do not apply when wind speed favors drift beyond the area intended for 

treatment.

Requirements for Drip Chemigation:

 1) The system must contain a functional check valve, vacuum relief valve and

 low pressure drain appropriately located on the irrigation pipeline to prevent 

water source contamination from back flow.

2) The pesticide injection pipeline must contain a functional, automatic, quickclosing check valve to prevent the flow of fluid back toward the injection 

pump.

3) The pesticide injection pipeline must also contain a functional, normally 

closed, solenoid-operated valve located on the intake side of the injection 

pump and connected to the system interlock to prevent fluid from being 

withdrawn from the supply tank when the irrigation system is either 

automatically or manually shut down.

4) The system must contain functional interlocking controls to automatically 

shut off the pesticide injection pump when the water pump motor stops.

5) The irrigation line or water pump must include a functional pressure switch,

which will stop the water pump motor when the water pressure decreases to 

the point where pesticide distribution is adversely affected.
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 20 of 29 December 20, 2011

6) Systems must use a metering pump, such as a positive displacement injection

pump (e.g., diaphragm pump), effectively designed and constructed of

materials that are compatible with pesticides and capable of being fitted with

a system interlock.

STORAGE AND DISPOSAL

Do not contaminate water, food, or feed by storage and disposal.

PESTICIDE STORAGE

Store refrigerated (~4oC). Reclose container of unused portions of SOYACYST LF.

PESTICIDE DISPOSAL

To avoid wastes, use all material in this container by application according to label 

directions. If wastes cannot be avoided, offer remaining product to a waste disposal 

facility or pesticide disposal program (often such programs are run by state or local 

governments or by industry).

CONTAINER HANDLING

[Plastic containers with capacities equal to or less than 5 gallons:] Nonrefillable 

container. Do not reuse or refill this container. Triple rinse container (or equivalent) 

promptly after emptying. Triple rinse as follows: Empty the remaining contents into 

application equipment or a mix tank and drain for 10 seconds after the flow begins to 

drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour 

rinsate into application equipment or a mix tank, or store rinsate for later use or 

disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure 

two more times. Then offer for recycling if available or puncture and dispose of in a 

sanitary landfill, or by incineration. Do not burn, unless allowed by state and local 

ordinance. If burned, stay out of smoke. 

[Plastic containers with capacities greater than 5 gallons:] Nonrefillable container. 

Do not reuse or refill this container. Triple rinse container (or equivalent) promptly 

after emptying. Triple rinse as follows: Empty the remaining contents into 

application equipment or a mix tank. Fill the container 1/4 full with water. Replace 

and tighten closures. Tip container on its side and roll it back and forth, ensuring at 

least one complete revolution, for 30 seconds. Stand the container on its end and tip 

it back and forth several times. Turn the container over onto its other end and tip it 

back and forth several times. Empty the rinsate into application equipment or a mix 

tank, or store rinsate for later use or disposal. Repeat this procedure two more times. 

Then offer for recycling if available or puncture and dispose of in a sanitary landfill, 

or by incineration. Do not burn, unless allowed by state and local ordinance. If 

burned, stay out of smoke.
Proposed Label for Soyacyst LF

Sub-Label B

Pasteuria Bioscience, Inc. 21 of 29 December 20, 2011

WARRANTY STATEMENT

Pasteuria Bioscience, Inc. (PBI) warrants that this product conforms to its label 

description and is suitable for its intended use if stored and used in accordance with 

the Directions for Use. To the extent consistent with applicable law, PBI makes no 

warranty, express or implied, of merchantability, fitness or otherwise concerning the 

use of this product other than as indicated on this label. To the extent consistent with 

applicable law, user assumes all risks of use, storage or handling not in accordance 

with accompanying directions.
Proposed Label for Soyacyst ST

Sub-label C

Pasteuria Bioscience, Inc. 22 of 29 December 20, 2011

SOYACYST LF

Biological control for use on soybean against soybean cyst nematode

WITH THE ALTERNATE BRAND NAME:

SOYACYST ST

Biological control for use on soybean seed against soybean cyst nematode

SUB-LABEL C

FOR SEED TREATMENT
Proposed Label for Soyacyst ST

Sub-label C

Pasteuria Bioscience, Inc. 23 of 29 December 20, 2011

SUB-LABEL C

SOYACYST LF 

Biological control for use on soybean against soybean cyst nematode

WITH THE ALTERNATE BRAND NAME:

SOYACYST ST 

Biological control for use on soybean seed against soybean cyst nematode

 

Active Ingredient: Pasteuria nishizawae – Pn1* ........................................ 33.29%

Other Ingredients: ............................................... .. ....... ............................. 66.71% 

Total: ....................................................................... ............. ........................ 100.00% 

* Contains at least 1.3x107 spores per g or 5.9x109 spores per pound.

KEEP OUT OF REACH OF CHILDREN

CAUTION

See additional precautionary and first aid statements on the back panel

Net Contents: 2.5, 5, 10 gallons

EPA Registration Number: 85004-O

EPA Est. Number: 

Manufactured for:

12085 Research Dr., Suite 185 +1 (386) 462-0008

Alachua, FL 32615 www.pasteuriabio.com/
Proposed Label for Soyacyst ST

Sub-label C

Pasteuria Bioscience, Inc. 24 of 29 December 20, 2011

PRECAUTIONARY STATEMENTS

HAZARDS TO HUMANS AND DOMESTIC ANIMALS

CAUTION

Harmful if inhaled. Avoid breathing spray mist. Remove and wash contaminated clothing 

before reuse.

FIRST AID

If inhaled:

• Move person to fresh air.

• If person is not breathing, call 911 or an ambulance, then give artificial 

respiration, preferably mouth-to-mouth if possible.

• Call a poison control center or doctor for treatment advice.

HOT LINE NUMBER

Have the product container or label with you when calling a poison control center or 

doctor, or going for treatment. For emergency information concerning this product, call 

the National Pesticide Information Center (NPIC) at 1-800-858-7378 seven days a week, 

6:30 am to 4:30 pm Pacific Time. During other times, call your poison control center at 1-

800-222-1222.

PERSONAL PROTECTIVE EQUIPMENT (PPE)

Applicators and other handlers must wear:

• Long-sleeved shirt and long pants

• Shoes plus socks

Mixers/loaders and applicators must wear a dust/mist filtering respirator meeting NIOSH 

standards of at least N-95, R-95, or P-95. Repeated exposure to high concentrations of 

microbial proteins can cause allergic sensitization.

Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such 

instructions are available, use detergent and hot water for washables. Keep and wash PPE 

separately from other laundry.
Proposed Label for Soyacyst ST

Sub-label C

Pasteuria Bioscience, Inc. 25 of 29 December 20, 2011

USER SAFETY RECOMMENDATIONS

Users should:

 • Wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 

 • Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly 

and put on clean clothing.

 • Remove PPE immediately after handling this product. As soon as possible, wash 

thoroughly and change into clean clothing.

ENVIRONMENTAL HAZARDS 

[Containers with capacities of 5 gallons or less:] For terrestrial uses, do not apply directly 

to water, or to areas where surface water is present or to intertidal areas below the mean 

high water mark.

Do not contaminate water when disposing of equipment wash waters or rinsate.

[Containers with capacities greater than 5 gallons:] Do not discharge effluent containing 

this product into lakes, streams, ponds, estuaries, oceans, or other waters unless in 

accordance with the requirements of a National Pollutant Discharge Elimination System 

(NPDES) permit and the permitting authority has been notified in writing prior to 

discharge. Do not discharge effluent containing this product to sewer systems without 

previously notifying the local sewage treatment plant authority. For guidance, contact your 

State Water Board or Regional Office of EPA.

For terrestrial uses, do not apply directly to water, or to areas where surface water is 

present or to intertidal areas below the mean high water mark.

Do not contaminate water when disposing of equipment wash waters or rinsate.

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner inconsistent with its 

labeling.

Do not use this product until you have read the entire label. Do not apply this product in a 

way that will contact workers or other persons, either directly or through drift. Only 

protected handlers may be in the area during application. For any requirement specific to 

your State or Tribe, consult the State or Tribe agency responsible for pesticide regulation. 
Proposed Label for Soyacyst ST

Sub-label C

Pasteuria Bioscience, Inc. 26 of 29 December 20, 2011

AGRICULTURAL USE REQUIREMENTS

Use this product only in accordance with its labeling and with the Worker Protection 

Standard, 40 CFR Part 170. This Standard contains requirements for the protection of 

agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 

agricultural pesticides. It contains requirements for training, decontamination, notification 

and emergency assistance. It also contains specific instructions and exceptions pertaining 

to the statements on this label about personal protective equipment (PPE) and restrictedentry interval. The requirements in this box apply only to the uses of this product that are 

covered by the Worker Protection Standard.

Do not enter or allow worker entry into treated areas during the restricted-entry interval 

(REI) of 4 hours.

EXCEPTION: If the product is soil injected or soil incorporated, the Worker Protection 

Standard, under certain circumstances, allows workers to enter the treated area if there will 

be no contact with anything that has been treated.

PPE required for early entry to treated areas (that is permitted under the Worker Protection 

Standard and that involves contact with anything that has been treated, such as plants, soil 

or water) is:

 • Water proof gloves

 • Coveralls

 • Shoes plus socks

NON- AGRICULTURAL USE REQUIREMENTS

The requirements in this box apply to uses of this product that are NOT within the 

scope of the Worker Protection Standard for agricultural pesticides (40 CFR Part 170). 

The WPS applies when this product is used to produce agricultural plants on farms, 

forests, nurseries or greenhouses.

Keep unprotected persons out of treatment areas until seeds have dried or been 

packaged.

PRODUCT INFORMATION

This product contains a biological nematicide for the control of the following nematode:

Soybean Cyst Nematode Heterodera glycines
Proposed Label for Soyacyst ST

Sub-label C

Pasteuria Bioscience, Inc. 27 of 29 December 20, 2011

FOR USE AS A SEED TREATMENT

Treatment of highly mechanically scarred or damaged seed, or seed known to be of low 

vigor and poor quality, except for the purpose of curative control of existing disease pests, 

may result in reduced germination and/or reduction of seed and seedling vigor. Treat a 

small quantity of seed using equipment similar to that planned for treating the total seed 

lot. Conduct germination tests on a small portion of seed before committing the total seed 

lot to a selected seed treatment. Due to seed quality, crop or variety sensitivity, and seed 

storage conditions beyond the control of manufacturer, no claims are made to guarantee the 

germination of carry-over seed or propagating material for all crop seed.

FOR USE AS A PRE-PLANT SEED TREATMENT

Treat only those seeds needed for immediate use, minimizing the interval between 

treatment and planting. Do not store excess treated seeds beyond planting time.

To achieve improved application coverage to the seed, dilute SOYACYST LF with water 

and apply directly to dry seed or mix with inoculants and/or other registered seed treatment 

coatings (e.g., colorants, polymers, etc.), insecticides and fungicides. Do not mix 

SOYACYST LF with any product containing a label prohibition against such mixing. 

When tank-mixing with any other registered seed treatment insecticide and/or fungicide, 

always read and follow all use directions, restrictions, and precautions of both 

SOYACYST LF and the tank mix partner(s). The resulting tank mix must be in 

accordance with the more restrictive label limitations and precautions. Do not exceed label 

dosage rates. Dilute with water to achieve improved application coverage to the seed. 

Please consult Pasteuria Bioscience, Inc. for additional information

(http://www.pasteuriabio.com/).

SOYBEAN 

For control of soybean cyst nematode, apply 2 to 5 fluid ounces of SOYACYST LF per 

100 Lbs (60–150 mL per 45.4 kg) of soybean seed. 

FOR USE AS A COMMERICAL SEED TREATMENT

To achieve improved application coverage to the seed, dilute SOYACYST LF with water 

and apply directly to dry seed or mix with inoculants and/or other registered seed treatment 

coating (e.g., colorants, polymers, etc.), insecticides and fungicides. Do not mix 

SOYACYST LF with any product containing a label prohibition against such mixing. 

When tank-mixing with any other registered seed treatment insecticide and/or fungicide, 

always read and follow all use directions, restrictions, and precautions of both 

SOYACYST LF and the tank mix partner(s). The resulting tank mix must be in 

accordance with the more restrictive label limitations and precautions. Do not exceed label 
Proposed Label for Soyacyst ST

Sub-label C

Pasteuria Bioscience, Inc. 28 of 29 December 20, 2011

dosage rates. Please consult Pasteuria Bioscience, Inc. for additional information 

(http://www.pasteuriabio.com/).

SOYBEAN 

For control of soybean cyst nematode, apply 2 to 5 fluid ounces of SOYACYST LF per 

100 Lbs (60–150 mL per 45.4 kg) of soybean seed. 

STORAGE AND DISPOSAL

Do not contaminate water, food, or feed by storage and disposal.

PESTICIDE STORAGE

Store refrigerated (~4oC). Reclose container of unused portions of SOYACYST LF.

PESTICIDE DISPOSAL

To avoid wastes, use all material in this container by application according to label 

directions. If wastes cannot be avoided, offer remaining product to a waste disposal 

facility or pesticide disposal program (often such programs are run by state or local 

governments or by industry).

CONTAINER HANDLING

[Plastic containers with capacities equal to or less than 5 gallons:] Nonrefillable container. 

Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application 

equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the 

container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application 

equipment or a mix tank, or store rinsate for later use or disposal. Drain for 10 seconds 

after the flow begins to drip. Repeat this procedure two more times. Then offer for 

recycling if available or puncture and dispose of in a sanitary landfill, or by incineration. 

Do not burn, unless allowed by state and local ordinance. If burned, stay out of smoke. 

[Plastic containers with capacities greater than 5 gallons:] Nonrefillable container. Do not 

reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. 

Triple rinse as follows: Empty the remaining contents into application equipment or a mix 

tank. Fill the container 1/4 full with water. Replace and tighten closures. Tip container on 

its side and roll it back and forth, ensuring at least one complete revolution, for 30 seconds. 

Stand the container on its end and tip it back and forth several times. Turn the container 

over onto its other end and tip it back and forth several times. Empty the rinsate into 

application equipment or a mix tank, or store rinsate for later use or disposal. Repeat this 

procedure two more times. Then offer for recycling if available or puncture and dispose of 

in a sanitary landfill, or by incineration. Do not burn, unless allowed by state and local 

ordinance. If burned, stay out of smoke.
Proposed Label for Soyacyst ST

Sub-label C

Pasteuria Bioscience, Inc. 29 of 29 December 20, 2011

WARRANTY STATEMENT

Pasteuria Bioscience, Inc. (PBI) warrants that this product conforms to its label description 

and is suitable for its intended use if stored and used in accordance with the Directions for 

Use. To the extent consistent with applicable law, PBI makes no warranty, express or 

implied, of merchantability, fitness or otherwise concerning the use of this product other 

than as indicated on this label. To the extent consistent with applicable law, user assumes 

all risks of use, storage or handling not in accordance with accompanying directions.