UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

JUN 11 2015 

MEMORANDUM 

OFFICE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION 

SUBJECT: BEAD Chemical Profile (BCP) for Registration Review: Diphenylamine 

(038501) 

FROM: 

THRU: 

Carl Chen, Plant Pathologist 

Biological Analysis Branch 

Donald 

Science 

Atwood, 

Information 

Entomologist 

and Analysis Branch 

& ~ #. ~ 

Economic 

Stephen Smearman, 

Analysis Branch 

Economist 

~ 

}L _ _1 A. ~ 

Biological and Economic Analysis Division (7503P) 

Arnet Jones, Chief 

Biological Analysis Br 

TO: Roy Johnson, Chemical Review Manager 

Risk Management and Implementation Branch 5 

Pesticide Re-evaluation Division (7508P) 

Product Review Panel date: May 27, 2015 

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The Biological and Economic Analysis Division (BEAD) Chemical Profile (BCP) provides an 

overview of the pest management role and quantitative usage information available for a 

pesticide. Information provided in this BCP may be used by stakeholders (e.g., users and 

registrants), Office of Pesticide Programs (OPP) risk and benefit assessors, OPP risk managers, 

and the general public during the Registration Review process of diphenylamine (DP A). 

DPA was registered in the United States in 1947. It is registered under Section 3 of the Federal 

Insecticide, Fungicide, and Rodenticide Act (FIFRA) as a growth regulator for use on apples. Its 

end-use products are formulated as an emulsifiable concentrate, soluble concentrate, or 

pressurized gas (NPIRS, 2015). Application is made as a post-harvest treatment with dipping, 

drenching, spraying, and thermal fogging (PPLS, 2015). 

DP A is only used post-harvest for reduction of scald on apples in storage. Scald is a 

physiological disorder that causes browning of the skin in storage rendering the apple 

unacceptable for fresh market (USDA, 2001). Apples are treated with the anti-scald agent after 

harvesting prior to placing in storage. In case of prolonged storage (4 months or longer) or 

particularly high danger of scald due to climatological conditions, a second treatment is 

applicable between the second and third months of storage (PPLS, 2015). In Washington, DPA 

is applied with thiabendazole to fruit that is susceptible to scald and fruit rot (USDA, 2001). 

There have been no BEAD benefits assessments or FIFRA Section 18 emergency exemption 

requests for DP A in the last 10 years. While an emergency exemption request may yield 

information about a chemical's importance or value that is not found in other EPA records, the 

lack of a FIFRA Section 18 assessment by BEAD does not specifically indicate the relative 

importance of this chemical. 

Quantitative usage information for DP A is only available from the California Department of 

Pesticide Regulation Use Report (CDPR). It reported that approximately 250 pounds of active 

ingredient were used on average annually between 2009 and 2013 in California on apples 

(CDPR, 2015). Obtaining the following information may improve future assessments related to 

the use and importance of DP A: 1) total pounds of active ingredient applied per year on a 

national and/or regional basis; 2) percent crop/site treated; 3) application rates: typical and 

maximum; 4) frequency and intervals of application; and 5) efficacy information/product 

performance. 

REFERENCES 

CDPR. 2015. Summary of Pesticide Use Report (PUR) Data-Indexed by Chemicals. 2009-

2013. California Department of Pesticide Registration (CDPR). Accessed May 2015 at 

http://www.cdpr.ca.gov/docs/purmain.htm. 

NPIRS. 2015. Diphenylamine formulation/use information. National Pesticide Information 

Retrieval System (NPIRS). Accessed May 2015 at http://npirs.ceris.purdue.edu. 

PPLS. 2015. EPA-approved diphenylamine products/labels. The Pesticide Product Label System 

(PPLS). Accessed May 2015 at http://ofmpub.epa.gov/apex/pesticides/f?p=PPLS:l. 

USDA. 2001. Crop Profile for Apples in Washington. The Western Integrated Pest Management 

Center. United State~ Department of Agriculture (USDA). Accessed May 2015 at 

http://www.ipmcenters.org/cropprofiles/docs/W AApples.pdf. 

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