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Posted: 03/02/2007 Updated: 05/10/2011

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Cisplatin

This page contains brief information about cisplatin and a collection of links

to more information about the use of this drug, research results, and

ongoing clinical trials.

US Brand Name(s): Platinol-AQ

Platinol

FDA Approved: Yes

Use in Cancer

Cisplatin is approved to be used alone or with other drugs to treat:

Bladder cancer that cannot be treated with surgery or radiotherapy.

Cervical cancer that is advanced and cannot be treated with surgery or radiotherapy.

Malignant mesothelioma that cannot be treated with surgery.

Non-small cell lung cancer that is locally advanced, advanced, or has metastasized (has spread to

other parts of the body) and cannot be treated with surgery.

Ovarian cancer that is advanced or has metastasized in patients whose disease has not gotten

better with other types of treatment or chemotherapy.

Squamous cell carcinoma of the head and neck that is locally advanced and cannot be treated

with surgery.

Testicular cancer in patients who have already had surgery or radiotherapy.

Cisplatin is also being studied in the treatment of other types of cancer.

More About Cisplatin

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Cisplatin - A lay language summary of important information about this drug

that may include the following:

warnings about this drug,

what this drug is used for and how it is used,

what you should tell your doctor before using this drug,

what you should know about this drug before using it,

other drugs that may interact with this drug, and

possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are

approved for. This patient information sheet applies only to approved uses of the drug. However, much of

the information may also apply to unapproved uses that are being studied.

NCI Issues Clinical Announcement for Preferred Method of Treatment for Advanced Ovarian Cancer:

Questions and Answers - Information about the use of this drug to treat cancer.

Research Results

Clinical Trial Results: Cisplatin Plus Gemcitabine Improves Survival of Patients with Advanced Biliary Tract

Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Cisplatin - National Cancer Institute Page 1 of 2

http://www.cancer.gov/cancertopics/druginfo/cisplatin 6/28/2011
Clinical Trial Results: Cisplatin No Better than Standard Therapy for Anal Canal Cancer - Important clinical

trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Stomach Cancer Drug, S-1, Given With Cisplatin, Shows Promise in Japanese Trial -

Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy Before Surgery May Increase Survival in Stomach Cancer - Important

clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Meta-Analysis Suggests Cisplatin Superior to Carboplatin for Advanced Non-Small

Cell Lung Cancer (NSCLC) - Important clinical trial results for this drug, background information, and how

the trial was done.

Clinical Trial Results: Long-Term Data Support Cisplatin-Based Chemoradiation for Cervical Cancer -

Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Elderly Benefit From Chemotherapy After Surgery for Early Non-Small Cell Lung

Cancer (NSCLC) - Important clinical trial results for this drug, background information, and how the trial was

done.

Clinical Trial Results: Surgery Does Not Improve Survival for Advanced Non-Small Cell Lung Cancer

(NSCLC) Patients - Important clinical trial results for this drug, background information, and how the trial

was done.

Clinical Trial Results: Patients With Esophageal Cancer May Be Able to Avoid Surgery - Important clinical

trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Impact of Intraperitoneal Chemotherapy on Quality of Life During Ovarian Cancer

Treatment - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: ERCC1 Expression in Lung Cancer May Predict Survival Benefit from Cisplatin -

Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy Superior to Whole-Abdominal Radiation Therapy for Uterine Sarcoma

- Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Cisplatin Improves Survival in Non-Small Cell Lung Cancer (NSCLC) - Important

clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy During Radiation Treatment Improves Outcomes in Nasopharyngeal

Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Cisplatin Plus Topotecan Gives Advanced Cervical Cancer Patients More Time -

Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy Better Than Radiation for Advanced Endometrial Cancer - Important

clinical trial results for this drug, background information, and how the trial was done.

Clinical Trials Accepting Patients

Find Clinical Trials for Cisplatin - Check for trials from NCI's list of cancer clinical trials now accepting

patients.

Important: The drug information on this Web page is meant to be educational. It is not a substitute for

medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this

drug, or precautions to be taken while using it. Please see your health care professional for more

information about your specific medical condition and the use of this drug.

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A Service of the National Cancer Institute

Cisplatin - National Cancer Institute Page 2 of 2

http://www.cancer.gov/cancertopics/druginfo/cisplatin 6/28/2011