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|   | o | REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|--------|---|------------------------------------------------------------------------------------------------|

|   | x | ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|--------|---|--------------------------------------------------------------------------------------|

|   | o | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|--------|---|------------------------------------------------------------------------------------------|

|   | o | SHELL COMPANY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|--------|---|---------------------------------------------------------------------------------------------|

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| Title of each class                                                                           |   | Name of each exchange on which registered |
|-----------------------------------------------------------------------------------------------|--------|-------------------------------------------|
| American Depositary Shares, each representing 10ordinary shares, par value NIS 0.01 per share |   | Nasdaq Capital Market                     |
|                                                                                          |   |                                      |
| Ordinary shares, par value NIS 0.01 per share                                                 |   | Nasdaq Capital Market*                    |

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| Large accelerated filer o | Accelerated filer o | Non-accelerated filer x |
|---------------------------|---------------------|-------------------------|

| U.S. GAAP o | International Financial Reporting Standards as issued by the International Accounting Standards Board x | Other o |
|-------------|---------------------------------------------------------------------------------------------------------|---------|

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| Exhibit Number  |   | Exhibit Description                                                                                                                                                                                                                |   |
|-----------------|--------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|
|            |   |                                                                                                                                                                                                                               |   |
| 2.1(5)          |   | Articles of Association of the Registrant, as amended May 15, 2012.                                                                                                                                                                |   |
|            |   |                                                                                                                                                                                                                               |   |
| 2.2(2)          |   | Form of Deposit Agreement dated as of July 21, 2011 among BioLineRx, Ltd., The Bank of New York Mellon, as Depositary, and all Owners and Holders from time to time of American Depositary Shares issued thereunder.               |   |
|            |   |                                                                                                                                                                                                                               |   |
| 2.3(2)          |   | Form of American Depositary Receipt; the Form is Exhibit A of the Form of Depositary Agreement.                                                                                                                                    |   |
|            |   |                                                                                                                                                                                                                               |   |
| 4.3(1)          |   | Employment Agreement with Kinneret Savitsky, Ph.D., dated October 13, 2004.                                                                                                                                                        |   |
|            |   |                                                                                                                                                                                                                               |   |
| 4.5(1)          |   | Employment Agreement with Philip Serlin, dated May 24, 2009.                                                                                                                                                                       |   |
|            |   |                                                                                                                                                                                                                               |   |
| 4.6†(1)   |   | License Agreement entered into as of January 10, 2005, by and between BioLine Innovations Jerusalem L.P. and B.G. Negev Technologies and Applications Ltd.                                                                         |   |
|            |   |                                                                                                                                                                                                                               |   |
| 4.7(1)          |   | Assignment Agreement dated as of January 1, 2009 entered into by and between BioLine Innovations Jerusalem L.P. and BioLineRx Ltd.                                                                                                 |   |
|            |   |                                                                                                                                                                                                                               |   |
| 4.16†(1)  |   | License Agreement between Innovative Pharmaceutical Concepts, Inc. and BioLineRx Ltd. dated November 25, 2007.                                                                                                                     |   |
|            |   |                                                                                                                                                                                                                               |   |
| 4.17†(11) |   | Amended and Restated License and Commercialization Agreement by and among Ikaria Development Subsidiary One LLC and BioLineRx Ltd. and BioLine Innovations Jerusalem L.P. dated August 26, 2009, as amended and supplemented. |   |
|            |   |                                                                                                                                                                                                                               |   |
| 4.18(10)        |   | BioLineRx Ltd. Amended and Restated 2003 Share Incentive Plan.                                                                                                                                                                     |   |
|            |   |                                                                                                                                                                                                                               |
| 4.19(1)         |   | Lease Agreement between Kaps-Pharma Ltd. and BioLine Innovations Jerusalem L.P., dated July 10, 2005, and Extension to Lease Agreement, dated December 4, 2008.                                                                    |
|            |   |                                                                                                                                                                                                                               |
| 4.20(1)         |   | Amendment to Employment Agreement with Kinneret Savitsky, Ph.D., dated January 2, 2004.                                                                                                                                            |
|            |   |                                                                                                                                                                                                                               |
| 4.21(1)         |   | Employment Agreement with Leah Klapper, Ph.D., dated January 27, 2005.                                                                                                                                                             |
|            |   |                                                                                                                                                                                                                               |
| 4.28(1)         |   | Sponsored Research Agreement entered into as of June 23, 2011 by and between Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. and BioLineRx Ltd.                                                     |
|            |   |                                                                                                                                                                                                                               |
| 4.29(1)         |   | License Agreement entered into as of June 23, 2011 by and between Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. and BioLineRx Ltd.                                                                |
|            |   |                                                                                                                                                                                                                               |
| 4.30(4)         |   | Employment Agreement with David Malek, dated August 8, 2011                                                                                                                                                                        |
|            |   |                                                                                                                                                                                                                               |
| 4.31(3)         |   | Form of Warrant to purchase American Depositary Shares                                                                                                                                                                             |
|            |   |                                                                                                                                                                                                                               |
| 4.32(7)         |   | Form of Warrant to purchase American Depositary Shares                                                                                                                                                                             |
|            |   |                                                                                                                                                                                                                               |
| 4.33†(8)  |   | License Agreement entered into as of September 2, 2012 by and between BioLineRx Ltd. and Biokine Therapeutics Ltd.                                                                                                                 |
|            |   |                                                                                                                                                                                                                               |
| 4.34(10)        |   | Consulting Agreement with Arnon Aharon, M.D., dated January 1, 2014                                                                                                                                                                |

----

| Exhibit Number  |   | Exhibit Description                                                                                                                                                                                                                                                                      |   |
|-----------------|--------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 4.35(10)† |   | License Agreement entered into as of February 15, 2011 by Valorisation-Recherche, Limited Partnership, and BioLineRx Ltd.                                                                                                                                                                |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 4.36(9)         |   | Executive Compensation Plan                                                                                                                                                                                                                                                              |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 4.37(11)        |   | Lease Agreement entered into as of August 7, 2014 between S.M.L. Solomon Industrial Buildings Ltd. and Infrastructure Management and Development Established by C.P.M. Ltd. as Lessor and the Registrant as Lessee, as amended December 9, 2014 (English summary of the Hebrew original) |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 4.38†(11) |   | Investment and Collaboration Agreement entered into as of December 16, 2014 between Novartis Pharma AG and the Registrant                                                                                                                                                                |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 4.39†     |   | License Agreement by and between the Registrant and Wartner Europe BV dated as of December 22, 2014                                                                                                                                                                                      |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 8.1(1)          |   | List of subsidiaries of the Registrant.                                                                                                                                                                                                                                                  |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 12.1            |   | Certification by Chief Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                                       |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 12.2            |   | Certification by Chief Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                                       |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 13.1(11)        |   | Certification by Chief Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002                                                                                                                                        |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 13.2(11)        |   | Certification by Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002                                                                                                                                        |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 15.1(3)         |   | Form of Purchase Agreement between BioLineRx Ltd. and the Purchasers named therein, dated February 15, 2012                                                                                                                                                                              |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 15.4(7)         |   | Subscription Agreement between BioLineRx Ltd. and OrbiMed Israel Partners Limited Partnership, dated February 6, 2013                                                                                                                                                                    |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 15.5(11)        |   | Consent of Kesselman & Kesselman, Certified Public Accountant (Isr.), a member of PricewaterhouseCoopers International Limited, independent registered public accounting firm for the Registrant.                                                                                    |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 15.6(6)         |   | Purchase Agreement between BioLineRx Ltd. and Lincoln Park, LLC, dated May 28, 2014                                                                                                                                                                                                      |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |
| 15.7(6)         |   | Registration Rights Agreement between BioLineRx Ltd. and Lincoln Park, LLC, dated May 28, 2014                                                                                                                                                                                           |   |
|            |   |                                                                                                                                                                                                                                                                                     |   |

| † | Portions of this exhibit have been omitted and filed separately with the Securities and Exchange Commission pursuant to a confidential treatment request. |
|---------|-----------------------------------------------------------------------------------------------------------------------------------------------------------|

| (1)  | Incorporated by reference to the Registrant’s Registration Statement on Form 20-F (No. 001-35223) filed on July 1, 2011. |
|-----------|--------------------------------------------------------------------------------------------------------------------------------|

| (2) | Incorporated by reference to Exhibit 1 of the Registration Statement on Form F-6 (No. 333-175360) filed by the Bank of New York Mellon with respect to the Registrant’s American Depositary Receipts. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

----

| (3) | Incorporated by reference to the Registrant’s Form 6-K filed on February 15, 2012. |
|-----|------------------------------------------------------------------------------------------|

| (4) | Incorporated by reference to the Registrant’s Registration Statement on Form F-1 (No. 333-179792) filed on February 29, 2012. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------|

| (5) | Incorporated by reference to the Registrant’s Registration Statement on Form S-8 (No. 333-183976) filed on September 19, 2012. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------|

| (6) | Incorporated by reference to the Registrant’s Form 6-K filed on May 30, 2014. |
|-----|-------------------------------------------------------------------------------------|

| (7) | Incorporated by reference to the Registrant’s Form 6-K filed on February 6, 2013. |
|-----|-----------------------------------------------------------------------------------------|

| (8) | Incorporated by reference to the Registrant’s Form 6-K filed on October 16, 2012. |
|-----|-----------------------------------------------------------------------------------------|

| (9) | Incorporated by reference to the Registrant’s Form 6-K filed on November 13, 2013. |
|-----|------------------------------------------------------------------------------------------|

| (10)   | Incorporated by reference to the Registrant’s Annual Report on Form 20-F filed on March 17, 2014. |
|--------|---------------------------------------------------------------------------------------------------------|
|   |                                                                                                    |
| (11)   | Incorporated by reference to the Registrant’s Annual Report on Form 20-F filed on March 23, 2015. |

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|   | BIOLINERX LTD. |                       |
|--------|----------------|----------------------------|
|   |           |                       |   |
|   | By:            | /s/ Kinneret Savitsky |   |
|   |           | Kinneret Savitsky, Ph.D.   |   |
|   |           | Chief Executive Officer    |   |
|   |           |                       |   |

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