EX-4.43



 EXHIBIT 4.43 

FIFTH SUPPLEMENTAL INDENTURE (this “Fifth Supplemental Indenture”), dated as of December 4, 2014, among Navios Maritime
Acquisition Corporation, a Marshall Islands corporation, (the “Company”), Navios Acquisition Finance (US) Inc., a Delaware corporation (together with the Company, the “Co-Issuers”), and Samos Shipping Corporation
(the “Guaranteeing Subsidiary”), a Marshall Islands corporation and an indirect subsidiary of the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee
(or its permitted successor) under the Indenture referred to below (the “Trustee”) and as collateral trustee (or its permitted successor) under the Indenture referred to below (the “Collateral Trustee”). 

WITNESSETH 
 WHEREAS, the
Co-Issuers and the Guarantors have heretofore executed and delivered to the Trustee an indenture (the “Indenture”), dated as of November 13, 2013 providing for the issuance of 8.125% First Priority Ship Mortgage Notes due 2021
(the “Notes”); 
 WHEREAS, the Indenture provides that under certain circumstances the Guaranteeing
Subsidiary shall execute and deliver to the Trustee a supplemental indenture pursuant to which the Guaranteeing Subsidiary shall unconditionally guarantee all of the Co-Issuers’ obligations under the Notes and the Indenture on the terms and
conditions set forth herein (the “Note Guarantee”); and 
 WHEREAS, pursuant to Section 9.01 of the Indenture,
the Trustee is authorized to execute and deliver this Fourth Supplemental Indenture. 
 NOW, THEREFORE, in consideration of the foregoing
and for other good and valuable consideration, the receipt of which is hereby acknowledged, the Guaranteeing Subsidiary and the Trustee mutually covenant and agree for the equal and ratable benefit of the Holders of the Notes as follows: 

1. CAPITALIZED TERMS. Capitalized terms used herein without definition shall have the meanings assigned to them in the Indenture. 

2. AGREEMENT TO GUARANTEE. The Guaranteeing Subsidiary hereby agrees to provide an unconditional Guarantee, on and subject to the terms,
conditions and limitations set forth in the Notation of Guarantee and in the Indenture, including, but not limited, to Article Ten thereof. 

3. NEW YORK LAW TO GOVERN. THIS FIFTH SUPPLEMENTAL INDENTURE SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF
NEW YORK, WITHOUT GIVING EFFECT TO CONFLICTS OF LAW PRINCIPLES TO THE EXTENT THAT THE APPLICATION OF THE LAWS OF ANOTHER JURISDICTION WOULD BE REQUIRED THEREBY. 

4. COUNTERPARTS. The parties may sign any number of copies of this Fifth Supplemental Indenture. Each signed copy shall be an original, but
all of them together represent the same agreement. 







 5. EFFECT OF HEADINGS. The Section headings herein are for convenience only and shall not affect
the construction hereof. 
 6. THE TRUSTEE. The Trustee shall not be responsible in any manner whatsoever for or in respect of the validity
or sufficiency of this Fifth Supplemental Indenture or for or in respect of the recitals contained herein, all of which recitals are made solely by the Guaranteeing Subsidiary and the Co-Issuers. 







 IN WITNESS WHEREOF, the parties hereto have caused this Fifth Supplemental Indenture to be duly
executed and attested, all as of the date first above written. 
  

							
	SAMOS SHIPPING CORPORATION
			
			By:		 /s/ Anna Kalathakis

					Name:  		Anna Kalathakis
					Title:		Treasurer/Director
	
	 NAVIOS MARITIME ACQUISITION

    CORPORATION

			
			By:		 /s/ Vasiliki Papaefthymiou

					Name:		Vasiliki Papaefthymiou
					Title:		Secretary
	
	NAVIOS ACQUISITION FINANCE (US) INC.
			
			By:		 /s/ Vasiliki Papaefthymiou

					Name:		Vasiliki Papaefthymiou
					Title:		President/Secretary
	
	NAVIOS ACQUISITION EUROPE FINANCE INC.
			
			By:		 /s/ Alexandros Laios

			Name:		     Alexandros Laios
			Title:		     Director/Secretary
	
	LEFKADA SHIPPING CORPORATION
	KERKYRA SHIPPING CORPORATION
	ZAKYNTHOS SHIPPING CORPORATION
	DONOUSSA SHIPPING CORPORATION
	SCHINOUSA SHIPPING CORPORATION
	SIKINOS SHIPPING CORPORATION
	LIMNOS SHIPPING CORPORATION
	SKYROS SHIPPING CORPORATION
	ALONNISOS SHIPPING CORPORATION
	MAKRONISOS SHIPPING CORPORATION









 
							
	 IRAKLIA SHIPPING CORPORATION
 THASOS
SHIPPING CORPORATION SAMOTHRACE SHIPPING CORPORATION PAXOS SHIPPING CORPORATION
 ANTIPAXOS SHIPPING CORPORATION OINOUSSES SHIPPING CORPORATION ANTIPSARA
SHIPPING CORPORATION
 PSARA SHIPPING CORPORATION
 KITHIRA
SHIPPING CORPORATION ANTIKITHIRA SHIPPING CORPORATION AMINDRA NAVIGATION CO.
 SERIFOS SHIPPING CORPORATION FOLEGANDROS SHIPPING CORPORATION LEROS SHIPPING
CORPORATION
 KIMOLOS SHIPPING CORPORATION

			
			 By:    
  
		 /s/ Anna Kalathakis





							
			Name:		 Anna Kalathakis
			Title:				Treasurer/Director
	
	 SHINYO DREAM LIMITED
 SHINYO KANNIKA
LIMITED
 SHINYO LOYALTY LIMITED
 SHINYO NAVIGATOR LIMITED

SHINYO OCEAN LIMITED
 SHINYO SAOWALAK LIMITED

SHINYO KIERAN LIMITED

		
	By:    		 /s/ Alexandros Laios

			Name:  Alexandros Laios
			Title:  Director
	
	 AEGEAN SEA MARITIME HOLDINGS INC. THERA SHIPPING CORPORATION

TINOS SHIPPING CORPORATION
 AMORGOS SHIPPING CORPORATION

ANDROS SHIPPING CORPORATION ANTIPAROS SHIPPING CORPORATION
 CRETE
SHIPPING CORPORATION
 IKARIA SHIPPING CORPORATION
 IOS SHIPPING
CORPORATION
 KOS SHIPPING CORPORATION
 MYTILENE SHIPPING
CORPORATION










 
							
	 RHODES SHIPPING CORPORATION
 SIFNOS
SHIPPING CORPORATION
 SKIATHOS SHIPPING CORPORATION SKOPELOS SHIPPING CORPORATION

SYROS SHIPPING CORPORATION

		
	By:    		 /s/ George Achniotis

			Name:   George Achniotis
			Title:   President/Director
	
	WELLS FARGO BANK, NATIONAL
			         ASSOCIATION,

        as Trustee

			
			By:    		  

					Name:		
					Title:		
	
	WELLS FARGO BANK, NATIONAL
					 ASSOCIATION,
 as Collateral
Trustee

			
			By:    		  

					Name:		
					Title: