74161103724 DRAF101223689058370 C101DI

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See Attachment 002 (Page 4 Chemical structure sanitized attachment.pdf)

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Acid ester 

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Page 9 SANITIZED SUBMISSIONPart I, Section C, 2.a. Additional Consumer Use Text

Category of Use XXX: 4-Decanoyloxybenzoic acid (DOBA) - PMN substance The PMN substance is a bleach activator. For Laundry use: Practically no consumer exposure other than handling of the detergent. Clariant will recommend to the US customers the usage level of 2-5 % of DOBA in the powder laundry detergent. For 50 g of the detergent there will be approximately 1- 2.5 g of DOBA in the washing machine. The machine dilutes the detergent with 60 Liters water in the main wash, that means that we have 0.02 - 0.04 g per liter DOBA in the wash water. Since the PMN substance is in powder form and is physically blended with the detergent powder, there is no chemical reaction in the product. Once added to the water in laundry and clothes are added DOBA reacts under alkaline washing conditions with hydrogen peroxide and forms Peroxydecanoic acid (and para-Hydoxybenzoic acid as side product). Peroxydecanoic acid is the bleach active species and removes the stains ( via oxidation). Further, upon reaction or removal of stains, peroxydecanoic acid forms decanoic acid in the wash water (<0.04 g /liter in the wash water) DOBA can be compared to NOBS, which is known in the US market (products from P&G contain this bleach activator NOBS). However,unlike NOBS, DOBA is not a sensitizer. Category of Use XXX: 4-Decanoyloxybenzoic acid (DOBA) - PMN substance The PMN substance is a bleach activator. For Dishwashing Machine use: Practically no consumer exposure other than handling of the dish washing tablet. Clariant will recommend to the US manufacturers the usage level of 2-5 % of DOBA in the dish washing tablet. For 20 g of the dishwashing tablet (which will contain 2.0 - 5.0 % DOBA) there will be 0.04 - 1 g of DOBA in the machine. The machine dilutes the product with 20 - 40 Liters that means that we have approx. 0.02 - 0.03 g per Liter of DOBA in the dishwashing machine. Since the PMN substance is in powder form and is physically blended with the dish washing powder to make a tablet, there is no chemical reaction in the product. Once added to the water in the dish washing machine and dishes are added, DOBA reacts under alkaline washing conditions with hydrogen peroxide and forms Peroxydecanoic acid (and para-Hydoxybenzoic acid as side product). Peroxydecanoic acid is the bleach active species and removes the stains ( via oxidation). Further, upon reaction or removal of stains, peroxydecanoic acid forms decanoic acid in the wash water (<0.04 g /liter in the wash water) Amount of DOBA (decanoic acid and para-hydroxydecanoic acid) is expected to be <0.04 g/liter (similar to amount mentioned earlier for laundry usage) DOBA can be compared to NOBS, which is known in the US market (products from P&G contain this bleach activator NOBS). However, unlike NOBS, DOBA is not a sensitizer.

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Page 17 SANITIZED SUBMISSIONPage 18 SANITIZED SUBMISSION001 Method I request CAS IES Sanitized attachment.pdf Pt.I, Sec.B, 1c. 5 002 Structure Page 4 Chemical structure sanitized attachment.pdf Pt.I, Sec.B, 1e. 1 003 Sanitized Skin sensitization_robust summary Skin sensitization_robust summary sanitized version.pdf 2 004 Acute oral sanitized copy Acute oral tox sanitized copy.pdf 25 005 Acute oral sanitized copy Acute oral tox_robus summary sanitized copy.pdf 2 006 HPLC HPLC Sanitized.pdf 7 007 Biodegradability Sanitized Ready biodegradability sanitized copy.pdf 9 008 Primary skin irritation sanitized copy primary skin irritation sanitized copy.pdf 26 009 Bacterial reverse ames test sanitized bacterial reverse Ames test sanitized copy.pdf 36 010 NMR NMR sanitized copy.pdf 2 011 Acute Fish sanitized Acute tox Fish sanitized copy.pdf 19 012 LLNA sanitized LLNA Sanitized copy.pdf 36 013 Primary eye sanitized copy Primary eye irritation sanitized copy.pdf 28 014 Skin sensitization sanitized copy Skin Sensitization sanitized copy.pdf 35 015 Sanitized MSDS Sanitized MSDS.pdf 6

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### ATTACHMENT HEADER SHEET
Attachment Number 001 Attachment Name Method I request 

### Associated PMN Section Number

Pt.I, Sec.B, 1c. Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 002 Attachment Name Structure 

### Associated PMN Section Number

Pt.I, Sec.B, 1e. Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 003 Attachment Name Sanitized Skin sensitization_robust summary 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 004 Attachment Name Acute oral sanitized copy 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 005 Attachment Name Acute oral sanitized copy 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 006 Attachment Name HPLC 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 007 Attachment Name Biodegradability Sanitized 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 008 Attachment Name Primary skin irritation sanitized copy 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 009 Attachment Name Bacterial reverse ames test sanitized 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 010 Attachment Name NMR 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 011 Attachment Name Acute Fish sanitized 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 012 Attachment Name LLNA sanitized 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 013 Attachment Name Primary eye sanitized copy 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 014 Attachment Name Skin sensitization sanitized copy 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370

### ATTACHMENT HEADER SHEET
Attachment Number 015 Attachment Name Sanitized MSDS 

### Associated PMN Section Number

N/A Does not contain CBI 

### Report Number DRAF101223689058370