UNITED STATES SECURITIES AND EXCHANGE COMMISSIONWASHINGTON, D.C. 20549 FORM 10-K [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2008 [ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE
SECURITIES EXCHANGE ACT OF 1934 For the transition period from _______ to _______. MANHATTAN SCIENTIFICS, INC.(Name of small business issuer in its charter) Delaware000-2841185-0460639(State of Incorporation)(Commission File Number)(IRS Employer Identification No.)  405 Lexington Avenue, 32nd Floor, New York, New York, 10174 (Address of principal executive offices) (Zip code)  Issuer's telephone number: (212) 551-0577 Securities registered pursuant to Section 12(b) of the Act: None  Securities registered pursuant to Section 12(g) of the Act: Common Stock, $0.001 par value (Title of Class)  Indicate by check mark if the issuer is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act.  Yes [   ] No [X]  Indicate by check mark if the issuer is not required to file reports pursuant to Section 13 or 15(d) of the Exchange Act. Yes [   ] No [X]  Indicate by check mark whether the issuer (1) filed all reports required to be filed by Section 13 or 15(d) of the Exchange Act during the past 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes [   ] No [X]  Indicate by check mark if disclosure of delinquent filers in response to Item 405 of Regulation S-B (§229.405) is not contained herein, and will not be contained, to the best of the registrant's knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. [  ]  Indicate by check mark whether the issuer is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company.  See definition of large accelerated filer, accelerated filer and smaller reporting company in Rule 12b-2 of the Exchange Act Large accelerated filer [  ] Accelerated filer [  ] Non-accelerated filer [  ] Smaller-reporting company [X]  Indicate by check mark whether the issuer is a shell company (a defined in Rule 12b-2 of the Act) Yes [   ] No [X]  The aggregate market value of the voting and non-voting common equity held by non-affiliates of the issuer as of June 30, 2008 was $8,751,708.  For purposes of this computation, all executive officers, directors and 10% shareholders were deemed affiliates. Such a determination should not be construed as an admission that such 10% shareholders are affiliates.  As of March 10, 2009 there were 393,227,926 shares of common stock of the issuer issued and outstanding.      TABLE OF CONTENTS


PART IPAGEITEM 1.DESCRIPTION OF BUSINESS1ITEM 1A.RISK FACTORS6ITEM 1B.UNRESOLVED STAFF COMMENTS9ITEM 2.DESCRIPTION OF PROPERTIES9ITEM 3.LEGAL PROCEEDINGS9ITEM 4.SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS9PART IIITEM 5.MARKET FOR REGISTRANT'S COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND ISSUER PURCHASES OF EQUITY SECURITIES10ITEM 6SELECTED FINANCIAL DATA13ITEM 7MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS14ITEM7AQUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK17ITEM 8.FINANCIAL STATEMENTS AND SUPPLEMENTARY DATAF-1ITEM 9.CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL DISCLOSURE18ITEM 9A.CONTROLS AND PROCEDURES18ITEM 9B.OTHER INFORMATION18PART IIIITEM 10.DIRECTORS, EXECUTIVE OFFICERS, PROMOTORS AND CONTROL PERSONS; COMPLIANCE WITH SECTION 16(a) OF THE EXCHANGE ACT19ITEM 11.EXECUTIVE COMPENSATION21ITEM 12.SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS.23ITEM 13.CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE24ITEM 14.PRINCIPAL ACCOUNTANT FEES AND SERVICES24ITEM 15.EXHIBITS, FINANCIAL STATEMENT SCHEDULES25SIGNATURESEXHIBIT INDEX






PART I
Forward Looking Statements
This Form 10-K contains "forward-looking" statements including statements regarding our expectations of our future operations. For this purpose, any statements contained in this Form 10-K that are not statements of historical fact may be deemed to be forward-looking statements. Without limiting the foregoing, words such as "may," "will," "expect," "believe," "anticipate," "estimate," or "continue" or comparable terminology are intended to identify forward-looking statements. These statements by their nature involve substantial risks and uncertainties, and actual results may differ materially depending on a variety of factors, many of which are not within our control. These factors include, but are not limited to, economic conditions generally and in the industries in which we may participate, competition within our chosen industry,
including competition from much larger competitors, technological advances, and the failure by us to successfully develop business relationships. In addition, these forward-looking statements are subject, among other things, to our successful completion of the research and development of our technologies; successful commercialization and mass production of, among other things, the micro fuel cell, mid-range fuel cell, and haptics Internet applications; successful protection of our patents; and effective significant industry competition from various entities whose research and development, financial, sales and marketing and other capabilities far exceeds ours. In light of these risks and uncertainties, you are cautioned not to place undue reliance on these forward-looking statements. Except as required by law, we undertake no obligation to announce publicly revisions we make to these forward-looking statements to reflect the effect of events or circumstances that may arise after the date of this report. All
written and oral forward-looking statements made subsequent to the date of this report and attributable to us or persons acting on our behalf are expressly qualified in their entirety by this section.
ITEM 1. DESCRIPTION OF BUSINESS
COMPANY HISTORY
Manhattan Scientifics, Inc., a Delaware corporation, was formed through a reverse merger involving a public company in January 1998. The public company was incorporated in Delaware on August 1, 1995 under the name Grand Enterprises, Inc. ("Grand"). Grand was initially organized to market an unrelated patented product, but subsequently determined that its business plan was not feasible. In January 1998, Grand effected the reverse merger in a transaction involving Projectavision, Inc., another public company that was founded by Marvin Maslow, our former Chief Executive Officer. Projectavision was the owner of approximately 98% of Tamarack Storage Devices, Inc., a privately-held Texas corporation formed in 1992 to develop and market products based on the holographic data storage technology.  We are no longer engaged in development and commercialization of Holographic data storage technologies (technologies for the storage and
retrieval of data in the form of holographically stored light patterns, rather than magnetic). We sold this portfolio of approximately 21 patents surrounding these inventions during 2002.  In January 1998, Grand formed a wholly-owned subsidiary named Grand Subsidiary, Inc. Grand Subsidiary and Tamarack merged, Tamarack being the surviving corporation, and via the merger, Tamarack became a subsidiary of Grand. As consideration for merging Tamarack with Grand Subsidiary, Grand gave Projectavision and the other stockholders of Tamarack 44,000,000 shares of our common stock. In addition, in exchange for a note payable of $1.5 million plus accrued interest of $330,000 due to Projectavision from Tamarack, Grand gave Projectavision 182,525 shares of its Series A Preferred Stock and a warrant to purchase 750,000 shares of our common stock at an exercise price of $0.10 per share, which expired on January 7, 2008.  Mr. Maslow, our former Chief Executive Officer, purchased the warrant from Projectavision for




$25,000. The Series A Preferred Stock was subsequently converted into 9,435,405 shares of our common stock. In connection with this transaction, new personnel assumed the management of Grand, former management resigned, and Grand changed its name to Manhattan Scientifics, Inc.
Manhattan Scientifics, Inc., a development stage company, previously operated as a technology incubator that sought to acquire, develop and commercialize life-enhancing technologies in various fields, with emphasis in the areas of alternative energy, and consumer and commercial electronics. In that capacity, we have previously identified emerging technologies through strategic alliances with scientific laboratories, educational institutions, and scientists and leaders in industry and government.
In 2008, we purchased, in exchange for our common stock, Metallicum, Inc. and its licensed patented technology.  Through Metallicum, we hope to take advantage of a unique processing methodology for producing nanostructures in a wide range of ductile metals and alloys and we are now attempting to commercialize this new and revolutionary technology.  Nanostructured metals and alloys possess significantly enhanced mechanical properties that include, for example, increased strength without concurrent losses in ductility, and significantly increased resistance to fatigue fracture. Nanostructured commercially pure grades of titanium have proven to also possess excellent machinability as well as high toughness and strength.


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In the recent past, we have worked to develop and commercialize three technologies:
·
Micro fuel cell technology, which is designed to become an ultra efficient miniature electricity generator that converts hydrogen into electricity by chemical means, for portable electronic devices, including cellular telephones, as a substitute for lithium ion and other batteries in common use today.
·
Mid-range fuel cell technology, which is an ultra efficient medium-size electricity generating device that converts hydrogen into electricity, with potential applications including personal transportation, cordless appliances, power tools,wheelchairs,bicycles,boats,emergencyhomegenerators,militaryfieldcommunicationsandlaptopcomputers.
·
Haptics "Touch and Feel" computer applications, which is a technology that allows computer users to be able to touch and feel any objects they see on their computer screen with the aid of special "mouse." Detailed texture, object-weight, stickiness, viscosity and object density can be "felt" or sensed. Management believes this haptics technology may positively impact the way computers are used everywhere by introducing the ability to "touch." (Please see Haptics "Touch and Feel" Internet Applications and Investment in Novint Technologies, Inc.
We are also seeking to develop corporate opportunities to benefit our shareholders; however, other than as set forth in this document, we have not executed agreements or finalized arrangements for any other technologies or opportunities as of the date of this Form 10-K.
OUR DEVELOPMENT MODEL
Our goal has been to influence the future through the development of potentially disruptive or sea-change technologies. Our business model has previously been to: (i) identify significant technologies, (ii) acquire them or the rights to them, (iii) secure the services of inventors, engineers or other staff who were instrumental in their creation, (iv) provide or contract for suitable work facilities, laboratories, and other aids where appropriate, (v) prototype the technologies to demonstrate "proof of principle" feasibility, (vi) secure patent and or other intellectual property protection, (vii) secure early customers for product trials where feasible and appropriate, and (viii) commercialize through licenses, sales or cooperative efforts with other manufacturing and distribution firms.
Since our technologies are still in their development phase, we have generated only limited revenues. As such, the need for operating and acquisition capital is a continuous concern requiring the ongoing efforts of our management. We are not a large capital-user but have raised since our reverse merger in January 1998 approximately $18 million in capital from notes payable to stockholders, proceeds from convertible notes and net proceeds from common stock and preferred stock.  Our management intends to work diligently to raise capital on an as needed basis through private placements, registered public offerings, debt, and/or other financing vehicles.  During April 2008 through January 2009, we sold approximately $1,100,000 from a private placement offering.  The private placement originally provided for the offer and sale of up to 50,000,000 unregistered shares of our common stock at a price of $0.02 per share, for an aggregate
offering price of $1,000,000, and allowed us to accept or reject any oversubscription.
One of our most significant assets is the shares of common stock we own in Novint Technologies, Inc. (Novint).  We have used our Novint common stock to help raise capital and to fund operations.  During the year ended December 31, 2008, we issued 53,211 shares of Novint as payment of an accrued liability and recorded a gain on sale of those shares of $50,000.  During the year ended December 31, 2007, we distributed 92,216 shares of Novint as payment of $77,000 of a note payable due to a former officer, and issued 530,000 shares of Novint related to the issuance of convertible debt.  As of December 31, 2008, we owned 1,075,648 shares of Novint common stock.
We utilize the intellectual property sale/licensing model, and not a production model, though management is opportunistic and is open to explore all methods leading to commercializing our technologies. We intend to consider all appropriate avenues for the commercialization of our technologies.

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OUR TECHNOLOGIES
1. ADVANCED MATERIALS (METALLICUM, INC.)
In June 2008, we acquired Metallicum, Inc. (Metallicum) and its licensed patented technology.  We entered into a stock purchase agreement with Metallicum, Inc. to acquire all of the outstanding capital in exchange for 15,000,000 shares of our common stock.  An additional 15,000,000 shares of our common stock will be payable to Metallicum in the event of meeting certain milestones.

Metallicum is a nanotechnology start-up company located in Santa Fe, New Mexico. Metallicum has focused on the development and manufacture of nanostructured metals for medical implants and other applications.  Metallicum intends to establish manufacturing partner relationships with major Fortune 500 metals companies and strategic partnering with significant customers in the medical device & prosthetics industries as well as in auto, truck, & aircraft manufacturing industries. Metallicums initial products include noaostructured bulk metals and alloys in the form of rod, bar, wire and foil.

We purchased Metallicum to acquire its licensed rights to patented technology.  The technology is comprised of three US Patents (US Patent numbers 7152448, 6197129 and 6399215) for which Metallicum (subsequently, Manhattan) had been assigned an exclusive license rights by Los Alamos National Security LLC (LANL).  Under the license rights, Metallicum had all rights, title and interest throughout the world in and to any and all inventions, original works of authorship, developments, concepts, know-how, improvements on the patents or trade secrets whether or not patentable or registerable under copyright or similar laws.

In January 2009, we entered into a patent license agreement with Los Alamos National Security, LLC for the exclusive licensing use of certain technology relating to the manufacture and application of nanostructuring metals and alloys. Pursuant to such agreement we provided a non-refundable fee and 2,000,000 shares of our common stock. Additionally, we are required to pay an annual license fee starting in February 2010 and royalties on future net sales.
The technology is expected to trim thousands of pounds from airplanes and hundreds of pounds from cars without sacrificing structural strength or adding significant cost.  The nanostructured metals also have wide implications for use in the medical device and prosthetics industries including dental implants, replacements for hips, shoulders, knees and cardio vascular stents.  In December 2008, a manufacturing joint venture partner in Albuquerque, N.M. received U.S. Food and Drug Administration 510(k) clearance to market nanostructued titanium metal dental implants using our technology. This clearance positions us closer to our goal of commercializing our technology for nanostructured metals.  We are in talks with many of the key manufacturers of dental implants and have signed material testing agreements with several manufacturers.
2. FUEL CELL TECHNOLOGIES
We have conducted research to develop both micro and mid-range fuel cell technologies. A micro fuel cell is a high-energy miniature power source that converts alcohol or hydrogen into electricity. A mid-range fuel cell is a high power density medium sized power source that converts hydrogen into electricity. Fuel cells create electricity not by burning fuel, but by the process of electrochemically arranging the fuel's atoms to produce an electric current. Water or water vapor and in some cases carbon dioxide are the only emissions. In addition to producing harmless emissions, certain fuel cells have the potential to be an alternative to traditional energy sources because they use methanol and other sources of hydrogen as fuels. Methanol can be produced inexpensively from a variety of plant sources and is considered a renewable resource. Generally, methanol is regarded to be stable and safe although it is considered to be toxic in certain countries.
We have acquired technologies in the fields of both micro fuel cell and mid-range fuel cells.
MICRO FUEL CELL TECHNOLOGY
We believe that micro fuel cell-based power sources have the potential to replace and/or supplement conventional batteries as a charger to provide portable power sources. If perfected, we believe micro fuel cell technology could supply energy to consumer electronic products such as cellular phones, pagers, and other microelectronic devices more efficiently than conventional batteries.
As a result of our shortage of capital, however, no additional investment or further resulting progress was made with micro-fuel cell technology during 2007 or 2008.  Although, this technology still has a residual value, we have chosen to focus our limited resources on other technologies.




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MID RANGE FUEL CELL TECHNOLOGY
In addition to micro fuel cells, we have made significant progress in our continuing efforts to develop and commercialize mid-range fuel cell technologies. Mid-range fuel cell technologies are directed toward higher power applications, including consumer electronics (such as laptop computers), personal transportation devices (such as bicycles and scooters), power tools and appliances (such as vacuum cleaners and lawnmowers), and portable military electronics (such as military field radios). In contrast, micro fuel cell technologies address lower power applications such as cellular phones, pagers and other microelectronics devices.

In 2003, we granted a non-exclusive worldwide license of the mid range fuel cell technology to Ballard Power Systems where we received an initial payment of $300,000 upon execution of the license agreement and the right to receive an additional $200,000 upon commercial launch by Ballard Power Systems of a product using the technology.  In January 2004, we licensed our mid-range fuel cell technology to a Singapore company with manufacturing in China as part of our efforts to provide low cost fuel cell systems to Asian and other worldwide markets. Among other things, the contract gave the licensee non-exclusive rights to produce and sell fuel cell engines based on the NovArs technology. The agreement included an upfront payment of $150,000, royalties and 17.5% equity interest in the Singapore company.  In December 2005, we sold our equity interest in the licensee back to the licensee for $885,000.
As a result of our shortage of capital, however, no additional investment or further resulting progress was made with mid-range fuel cell technology during 2007 or 2008.  Although, this technology still has a residual value, we have chosen to focus our limited resources on other technologies.
3. HAPTICS "TOUCH AND FEEL" INTERNET APPLICATIONS
Haptics is an emerging technology that allows computer users to have the physical sensation of manipulating and touching objects on a computer screen as if they were three-dimensional, using a special mouse. Detailed texture and viscosity can be sensed, among many other aspects of touch.  We believe that haptics technology has the potential to significantly change the way computers are utilized, and that there are many promising applications. These include 3-dimensional, touch-enabled online shopping and computer gaming.
During 2000, we acquired exclusive licenses and sublicenses to certain haptics Internet applications from Novint.  We also acquired 36,606 shares of Novint common stock, and contracted with the developer of the licensed technology to perform research and development of the licensed applications for contract payments of $1,500,000. In May 2001, we acquired Teneo Computing, Inc., a private corporation with rights to certain haptics applications for dental simulation and oil and gas exploration. We licensed these rights exclusively to Novint in exchange for various enhanced and amended license rights with Novint in the areas of Internet applications and interactive applications. We also acquired an additional 4,066 shares of Novint common stock, increasing our ownership in Novint to 40,672 shares, subsequently split into 4,067,200 shares. For accounting purposes, we have treated the acquisition of the Novint common stock as one transaction.
COMPETITION
The markets in which we compete are highly competitive and constantly evolving. We face competition from leading researchers and manufacturers worldwide.   Many of our competitors have longer operating histories and significantly greater financial, marketing and other resources than we have. Furthermore, our competitors may introduce new products that address our potential markets. Competition could have a material adverse effect on our business, financial condition and results of our operations.
We believe that the principal competitive factors in our technology markets include without limitation:
·
capitalization;
·
cost of product;
·
type of fuel (hydrogen, methanol);
·
first to market with product in market segment;
·
strong intellectual portfolio;
·
product life/reliability;
·
strong customer base;
·
strong manufacturing and supplier relationships; and
·
benchmark power density and energy efficiency.

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ADVANCED MATERIALS

Our business model is based on licensing its technology to customers such as metals manufacturers. Although competing commercial products are provided by existing specialty metals companies, the only competing processes for creating nanostructured metals are either limited to producing thin films or cannot be economically scaled.  Metallicum does not yet face direct competition, but expects competition will emerge by 2010.
FUEL CELLS
In the last few years there has been a much greater interest in using fuel cells as an energy source for practical, lower powered applications such as automobiles and portable electronic devices. In addition, many automotive companies have indicated they will contribute several hundred million dollars as part of a global alliance with other entities to develop automotive engines powered by fuel cells.By reason of the innovative nature of the technologies we are developing, and the yet unproven markets for such technologies, the markets in which we compete may have barriers to entry. These include the perception of fuel cell technologies in general by the investment community, the costs associated with creating the infrastructure necessary for delivery of hydrogen and other fuels, and the general condition of the economy. There are others working toward similar objectives in order to





penetrate these markets and we anticipate additional companies will pursue the same goals. Those whose efforts we are aware of include, without limitation, Medis Technologies, MTI Micro, Samsung, Toshiba, and Smart Fuel Cells in the area of micro fuel cells; and Ballard (now our licensee), Prononex Technologies and Plug Power, Inc. in the area of mid-range fuel cells.
HAPTICS "TOUCH AND FEEL" INTERNET APPLICATIONS

With respect to touch-enabled products, we are aware of several companies that claim to possess touch and feel technology. In addition, we are aware of several companies that currently market unlicensed touch and feel products.  Many potential competitors, including Microsoft, LG Electronics, Logitech, Nokia, Samsung, Intel and others have greater financial and technical resources upon which to draw in attempting to develop products.
INTELLECTUAL PROPERTY / RESEARCH AND DEVELOPMENT
Our ability to compete depends in part on the protection of and our ability to defend our proprietary technology and on the goodwill associated with our trade names, service marks and other proprietary rights. However, we do not know if current laws will provide us with sufficient enough protection that others will not develop technologies similar or superior to ours, or that third parties will not copy or otherwise obtain or use our technologies without our authorization.
The success of our business will depend, in part, to identify technology, obtain patents, protect and enforce patents once issued and operate without infringing on the proprietary rights of others. Our success will also depend on our ability to maintain exclusive rights to trade secrets and proprietary technology we own, are currently developing and will develop. We can give no assurance that any issued patents will provide us with competitive advantages or will not be challenged by others, or that the patents of others will not restrict our ability to conduct business.
In addition, we rely on certain technology licensed from third parties, including Sandia National Laboratory and may be required to license additional technologies in the future. We do not know if these third-party licenses will be available or will continue to be available to us on acceptable commercial terms or at all. The inability to enter into and maintain any of these licenses could have a material adverse effect on our business, financial condition or results of our operations.
Policing unauthorized use of our proprietary technology and other intellectual property rights could entail significant expense. In addition, we do not know if third parties will bring claims of copyright or trademark infringement against us or claim that our use of certain technologies violates a patent or other intellectual property. Any claims of infringement, with or without merit, could be time consuming and expensive to defend, result in costly litigation, divert management attention, require us to enter into costly royalty or licensing arrangements or prevent us from using important technologies or methods, any of which could have a material adverse effect on our business, financial condition or results of our operations.

Patents are recorded at cost of $2,080,000. Amortization is charged against results of operations using the straight-line method over the estimated economic useful life. The patents were fully amortized at the end of the fiscal year ending December 31, 2008.  Amortization Expense recorded for our patents is shown as Research and Development Expense within the Consolidated Statement of Operations.



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Intellectual property is recorded at cost of $290,000 and consists of an exclusive license on two patents and a non-exclusive license on the third regarding nanostructured materials and various trade secrets regarding the manufacturing of these materials. Amortization of intellectual property is charged against results of operations using the straight line method over its estimated economic useful life.  The intellectual property related to the patents licenses and nanotechnology developed by Metallicum, Inc., is estimated to have a useful life of 10 years.  Manhattan Scientifics, Inc. directly acquired the patent licenses during 2009.  Amortization expense was $15,000 for the year ended December 31, 2008.

Research and development costs are expensed as incurred and amounted to $4,000 and $2,000 for the years ended December 31, 2008 and 2007, respectively.
SALES AND MARKETING
Although our technologies presently are in the development stage, we are engaged in an early commercialization program intended to facilitate the transition from development to licensing, manufacturing and/or sale. This program consists of preliminary dialogues with potential strategic partners, investors, manufacturers, potential licensees and/or purchasers.
EMPLOYEES
As of December 31, 2008, we had one full-time employee in general management. We do not expect any significant change in the total number of employees in the near future. Most of our research and development work has been performed by employees of our various research and development independent contractors (see below). We have historically indirectly funded the salaries of these individuals through our contract research and development payments to their employers. Although not technically our employees, we have considered these individuals to be an integral part of our research and development team.None of our employees or contractors is members of any union or collective bargaining organization. We consider our relationships with our employee and our independent contractor employees to be good.
As noted above, a significant portion of our research and development has been performed by independent contractors from whom we acquired or licensed certain technologies, and their various employees.  Our independent contractors utilize a number of their own various employees to satisfy their research and development obligations to us, and their employees are considered to be part of our research and development team.
ITEM 1A. RISK FACTORS
An investment in the Common Stock involves a high degree of risk. In addition to the other information in this Report, the following risk factors should be considered carefully in evaluating the Company and our business. If you decide to buy our securities, you should be able to afford a complete loss of your investment.
WE MAY NOT BE ABLE TO SUCCESSFULLY DEVELOP AND COMMERCIALIZE OUR TECHNOLOGIES WHICH WOULD RESULT IN CONTINUED LOSSES.
We are currently developing our technology and a commercial product. We have not generated any revenues and we are unable to project when we will achieve profitability, if at all. As is the case with any new technology, we expect the development process to continue. We cannot assure that our resources will be able to develop our technology fast enough to meet market requirements. We can also not assure that our technology will gain market acceptance and that we will be able to successfully commercialize the technologies. The failure to successfully develop and commercialize the technologies would result in continued losses and may require us to curtail operations.
BECAUSE WE HAVE EARNED VERY LITTLE IN REVENUES, THE SUCCESS OF OUR BUSINESS REQUIRES CONTINUED FUNDING. IF WE CANNONT RAISE THE MONEY WE NEED TO SUPPORT OUR OPERATIONS UNTIL WE EARN SIGNIFICANT REVENUES, WE MAY BE REQUIRED TO CURTAIL OR TO CEASE OUR OPERATIONS AND YOU COULD LOSE YOUR ENTIRE INVESTMENT.
Our ability to develop our business depends upon our receipt of money to continue our operations while we introduce our products and a market for them develops. If this funding is not received as needed, it is unlikely that we could continue our business, in which case you would lose your entire investment. Our ability to access the capital markets has been hindered generally by the general difficult economic climate, beginning in 2001, for small technology concept companies, without significant revenues or earnings.


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To the extent that we need additional funding, we cannot assure you that such financing will be available to us when needed, on commercially reasonable terms, or at all. If we are unable to obtain additional financing, we may be required to curtail the commercialization of our products and possibly cease our operations.
OUR ABILITY TO EFFECTUATE OUR BUSINESS MODEL MAY BE LIMITED, WHICH WOULD ADVERSELY EFFECT OUR BUSINESS AND FINANCIAL CONDITIONS.
Our future performance will depend to a substantial degree upon our ability to effectuate and generate revenues from our licensing and royalty business model. As a result, we may continue to incur substantial operating losses until such time as we are able to generate revenues from the sale or license of our products. There can be no assurance that businesses and customers will adopt our technology and products, or that businesses and prospective customers will agree to pay for or license our products. In the event that we are not able to significantly increase the number of customers that purchase or license our products, or if we are unable to charge the necessary prices or license fees, our financial condition and results of operations will be materially and adversely affected.
WE MAY FACE STRONG COMPETITION FROM LARGER, ESTABLISHED COMPANIES.
We likely will face intense competition from other companies, both globally and within the United States, in the development of haptics and fuel cell technologies, virtually all of which can be expected to have longer operating histories, greater name recognition, larger installed customer bases and significantly more financial resources and research and development facilities than Manhattan Scientifics. There can be no assurance that developments by our current or potential competitors will not render our proposed products obsolete.
WE MAY NOT BE ABLE TO ADEQUATELY PROTECT OUR INTELLECTUAL PROPERTY OR WE COULD BECOME INVOLVED IN LITIGATION WITH OTHERS REGARDING OUR INTELLECTUAL PROPERTY. EITHER OF THESE EVENTS COULD HAVE A MATERIAL ADVERSE EFFECT ON OUR BUSINESS.
We rely on a combination of intellectual property law, nondisclosure, trade secret and other contractual and technical measures to protect our proprietary right. Our success will depend, in part, on our technologys commercial viability and on the strength of our intellectual property rights. However, we cannot assure you that these provisions will be adequate to protect our intellectual property. In addition, the laws of certain foreign countries do not protect intellectual property rights to the same extent as the laws of the United States.
Although we believe that our intellectual property does not infringe upon the proprietary rights of third parties, competitors may claim that we have infringed on their products.
We could incur substantial costs in defending ourselves in suits brought against us for alleged infringement of another partys intellectual property rights as well as in enforcing our rights against others, and if we are found to infringe, the manufacture, sale and use of our or our customers or partners products could be enjoined. Any claims against us, with or without merit, would likely be time-consuming, requiring our management team to dedicate substantial time to addressing the issues presented. Furthermore, the parties bringing claims may have greater resources than we do.
OUR MANAGEMENT IS ABLE TO EXERCISE SIGNIFICANT INFLUENCE OVER ALL MATTERS REQUIRING SHAREHOLDER APPROVAL.
Our existing directors and executive officers are the beneficial owners of approximately 28% of the outstanding shares of common stock, excluding stock options. As a result, our existing directors, executive officers, principal shareholders and their respective affiliates, if acting together, would be able to exercise significant influence over all matters requiring shareholder approval, including the election of directors and the approval of significant corporate transactions. Such concentration of ownership may also have the effect of delaying or preventing a change in control of our company.
THE TRADING PRICE OF OUR COMMON STOCK MAY DECREASE DUE TO FACTORS BEYOND OUR CONTROL.
The trading price of our common stock is subject to significant fluctuations in response to numerous factors, including without limitation:
·
variations in anticipated or actual results of operations;
·
announcements of new products or technological innovations by us or our competitors;



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·
changes in earnings estimates of operational results by analysts;
·
inability of market makers to combat short positions on the stock;
·
an overall downturn in the financial markets and stock markets;
·
the use of stock to pay employees and consultants if sufficient working capital is not available;
·
inability of the market to absorb large blocks of stock sold into the market; and
·
developments or disputes concerning our intellectual property.
Moreover, the stock market from time-to-time has experienced extreme price and volume fluctuations, which have particularly affected the market prices for small technology companies without significant revenues. These broad market fluctuations may adversely affect the market price of our Common Stock. If our shareholders sell substantial amounts of their common stock in the public market, the price of our common stock could fall. These sales also might make it more difficult for us to sell equity or equity-related securities in the future at a price we deem appropriate.
WE HAVE NOT PAID CASH DIVIDENDS AND IT IS UNLIKELY THAT WE WILL PAY CASH DIVIDENDS IN THE FORESEEABLE FUTURE.
We plan to use all of our earnings, to the extent we have significant earnings, to fund our operations. We do not plan to pay any cash dividends in the foreseeable future. We cannot guarantee that we will, at any time, generate sufficient surplus cash that would be available for distribution as a dividend to the holders of our Common Stock. You should not expect to receive cash dividends on our Common Stock.
WE MAY NOT HAVE SUFFICIENT CAPITAL TO RUN OUR OPERATIONS.

If we are unable to obtain further financing, it may jeopardize our ability to continue our operations. To the extent that additional capital is raised through the sale of equity and/or convertible debt securities, the issuance of such securities could result in dilution to our shareholders and/or increased debt service commitments. If adequate funds are not available, we may be unable to sufficiently develop or maintain our existing operations.
WE HAVE THE ABILITY TO ISSUE ADDITIONAL SHARES OF OUR COMMON STOCK WITHOUT ASKING FOR SHAREHOLDER APPROVAL, WHICH COULD CAUSE YOUR INVESTMENT TO BE DILUTED.
Our Certificate of Incorporation currently authorizes the Board of Directors to issue up to 500,000,000 shares of Common Stock and 1,000,000 shares of Preferred Stock. The power of the Board of Directors to issue shares of Common Stock or warrants or options to purchase shares of Common Stock is generally not subject to shareholder approval. Accordingly, any additional issuance of our Common Stock may have the effect of further diluting your investment.
We require substantial working capital to fund our business. If we raise additional funds through the issuance of equity, equity-related or convertible debt securities, those securities may have rights, preferences or privileges senior to those of the holders of our Common Stock. The issuance of additional Common Stock or securities convertible into Common Stock by our management will also have the effect of further diluting the proportionate equity interest and voting power of holders of our Common Stock.
WE MAY RUN OUT OF AUTHORIZED CAPITAL PRIOR TO RECEIVING SHAREHOLDER APPROVAL TO AMEND OUR CERTIFICATE OF INCORPORATION TO INCREASE OUR AUTHORIZED CAPITAL.
As of December 31, 2008, our certificate of incorporation, as amended, authorizes us to issue 500,000,000 shares of common stock. If we are not able to increase our authorized capital, we may not be able to raise additional funds or pay service providers which could be harmful to our business or cause us to cease operations altogether.
LIMITED PUBLIC MARKET FOR OUR COMMON STOCK MAY AFFECT OUR SHAREHOLDERS' ABILITY TO SELL OUR COMMON STOCK.
Our Common Stock currently was traded on NASDAQ's Over-The-Counter Bulletin Board through May 2007.  Our Common Stock is currently traded on the Over the Counter Pink Sheets, which is generally considered to be a less efficient market than national exchanges. Consequently, the liquidity of our securities could be impaired, not only in the number of securities which could be bought and sold, but also through SEC regulations, delays in the timing of transactions, difficulties in obtaining price quotations, reduction in security analysts' and the new media's coverage of us, if any, and lower prices for our securities than might otherwise be attained. This circumstance could have an adverse effect on the ability of an investor to sell any shares of our common stock as well as on the selling price for such shares. In addition, the market price of our common stock may be significantly affected by various additional factors, including, but not limited





 to, our business performance, industry dynamics or changes in general economic conditions.




8


APPLICABILITY OF "PENNY STOCK RULES" TO BROKER-DEALER SALES OF OUR COMMON STOCK COULD HAVE A NEGATIVE EFFECT ON THE LIQUIDITY AND MAREKT PRICE OF OUR COMMON STOCK.
A penny stock is generally a stock that is not listed on a national securities exchange or NASDAQ, is listed in the "pink sheets" or on the NASD OTC Bulletin Board, has a price per share of less than $5.00 and is issued by a company with net tangible assets less than $5 million.
The penny stock trading rules impose additional duties and responsibilities upon broker-dealers and salespersons effecting purchase and sale transactions in Common Stock and other equity securities, including determination of the purchaser's investment suitability, delivery of certain information and disclosures to the purchaser, and receipt of a specific purchase agreement before effecting the purchase transaction.
Many broker-dealers will not effect transactions in penny stocks, except on an unsolicited basis, in order to avoid compliance with the penny stock trading rules. When our Common Stock is subject to the penny stock trading rules, such rules may materially limit or restrict the ability to resell our Common Stock, and the liquidity typically associated with other publicly traded equity securities may not exist.
ITEM 1B. UNRESOLVED STAFF COMMENTS
N/A
ITEM 2. DESCRIPTION OF PROPERTIES
Our principal executive office is at 405 Lexington Avenue, 32nd Floor, New York, New York, 10174. We lease approximately 300 square feet of office space on a month-to-month basis. The aggregate annual rent for this office space was $6,000 in 2008.  We believe our facilities are adequate for our current and planned business operations.
ITEM 3. LEGAL PROCEEDINGS
We are subject from time to time to litigation, claims and suits arising in the ordinary course of business. As of December 31, 2008, we were not a party to any material litigation, claim or suit whose outcome could have a material effect on our financial statements other than the litigation described above which was subsequently settled.

ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS
Our Board of Directors has adopted and approved an amendment to our Certificate of Incorporation to increase the authorized common stock from 250,000,000 shares to 500,000,000 shares (the Authorized Shares Amendment). A majority of the stockholders entitled to vote on the Authorized Shares Amendment voted in favor of the Amendment by written consent dated May 25, 2007.



9


PART II
ITEM 5. MARKET FOR REGISTRANTS COMMON EQUITY, RELATED STOCKHOLDER MATTERSAND ISSUER PURCHASES OF EQUITY SECURITIES
Starting on May 8, 2007, our Common Stock began trading and, currently trades, on the Over the Counter Pink Sheets under the symbol MHTX.PK after being removed from trading on NASDAQ's Over-The-Counter Bulletin Board under the symbol "MHTX.OB".  The following table sets forth for the periods indicated, the high and low per share bid information for our common stock for the fiscal years ended December 31, 2006, December 31, 2007 and December 31, 2008, as reported by www.nasdaq.com. Such high and low bid information reflects inter-dealer quotes, without retail mark-ups, mark-downs or commissions and may not represent actual transactions.
2006
High
Low
First Quarter
$
0.065
$
0.050
Second Quarter
$
0.075
$
0.047
Third Quarter
$
0.060
$
0.027
Fourth Quarter
$
0.044
$
0.012

2007
High
LowFirst Quarter.
$
0.039
$
0.012
Second Quarter
$    0.029
$    0.014
Third Quarter
$    0.030
$    0.010
Fourth Quarter
$    0.090
$    0.011

2008
High
LowFirst Quarter.
$
0.064
$
0.030
Second Quarter
$    0.053
$    0.030
Third Quarter
$    0.090
$    0.022
Fourth Quarter
$    0.063
$    0.025
As of December 31, 2008, we had 648 registered shareholders and 336,270,926 shares of Common Stock issued and outstanding.
DIVIDENDS.
We have never paid any cash dividends. We presently intend to reinvest earnings, if any, to fund the development and expansion of our business and, therefore, do not anticipate paying cash dividends on our common stock in the foreseeable future. The declaration of cash dividends will be at the discretion of our board of directors and will depend upon our earnings, capital requirements, financial position, general economic conditions and other pertinent factors.
RECENT SALES OF UNREGISTERED SECURITIES
During the past two years, we have issued unregistered securities in the following transactions in reliance on an exemption from registration pursuant to Section 4(2) of the Securities Act of 1933:
2008
In January 2008, we issued 200,000 shares of common stock for past services to consultants for a total value of $12,000 or $0.06 per share.

In January 2008, we issued 925,926 shares of common stock, $50,000 in cash, and 53,191 shares of Novint common stock in satisfaction of past legal fees totaling $133,000.

In April 2008, we issued 250,000 shares of common stock for services to a consultant for a total value of $12,500 or $0.05 per share.

In April 2008, we issued 200,000 shares of common stock for services to a consultant for a total value of $10,000 or $0.05 per share.




10


In June 2008, we issued 15,000,000 shares of common stock for the acquisition of Metallicum, Inc. for a total value of $305,000 or $0.02 per share..

In September 2008, we issued 750,000 shares of common stock for accrued legal services for a total value of approximately $16,000, the value of the services performed.

In October 2008, we agreed to issue 400,000 shares of common stock to a consultant for services for a total value of $14,000 or $0.035 per share. These shares were issued in November 2008.

During April 2008 through January 2009, we sold approximately $1,100,000 from a private placement offering.  The private placement originally provided for the offer and sale of up to 50,000,000 unregistered shares of our common stock at a price of $0.02 per share, for an aggregate offering price of $1,000,000, and allowed us to accept or reject any oversubscription.  The shares sold in the private placement were not issued until February 2009.  As a result, the sale of these shares is recorded as common stock on the accompanying consolidated balance sheet as of December 31, 2008 net of offering costs totaling $46,000.
2007
In May 2007, we issued 35,350,317 shares of common stock to various individuals for services with values totaling $707,006 based upon the fair value of the shares issued.
In May 2007, we issued 14,200,106 shares of common stock for settlement of debts totaling $71,000.
In October 2007, we issued 4,200,000 shares of common stock for services to an individual with a value of $60,900 based upon the fair value of the shares issued.
In October 2007, we issued 106,000,000 shares of common stock related to the conversion of convertible debt previously issued during 2007.  The convertible debt converted totaled $1,060,000 at which time the entire debt discount of $1,361,000 had been expensed.
In November 2007, we issued 1,000,000 shares of common stock to an individual for services with a value of $30,000 based upon the fair value of the shares issued.  In November 2007, we also issued 1,000,000 shares of common stock to an individual for services to be provided with a value of $30,000 based upon the fair value of the shares issued.
Securities Authorized for Issuance under Equity Incentive Plans
In 2000, our Board of Directors adopted the 2000 Equity Incentive Plan (the "2000 Plan"). The 2000 Plan authorizes the issuance of options, right to purchase Common Stock and stock bonuses to officers, employees, directors and consultants. We reserved 30,000,000 shares of our Common Stock for awards to be made under the 2000 Plan and registered the following:
·
September 14, 2001, we filed a registration statement on Form S-8 to register 900,000 of these shares.
·
November 19, 2001, we registered 550,000 shares of our common stock for issuance under the 2000 Plan.
·
January 30, 2002, we registered an additional 975,000 shares of our common stock for issuance under the 2000 Plan.
·
March 22, 2002, we registered an additional 925,000 shares of our common stock for issuance under the 2000 Plan.
·
July 12, 2002, we registered an additional 990,000 shares of our common stock for issuance under the 2000 Plan.
·
January 17, 2003, we registered an additional 8,000,000 of our common stock for issuance under the 2000 Plan.

The 2000 Plan is administered by a committee of two or more members of the Board of Directors or, if no committee is appointed, then by the Board of Directors. The 2000 Plan allows for the issuance of incentive stock options (which, pursuant to Section 422 of the Internal Revenue Code, can only be granted to employees), non-qualified stock options, stock appreciation rights, stock awards, or stock bonuses. The committee, or the Board of Directors if there is no committee, determines the type of option granted, the exercise price, the option term, which may be no more than ten years, terms and conditions of exercisability and methods of exercise. Options must vest within ten-years. Under the 2000 Plan, the exercise price may not be less than fair market value on the date of grant for the incentive stock options. The 2000 Plan also allows for the granting of Stock Appreciation Rights. No Stock Appreciation Rights have been granted. The number of shares under the 2000 Plan available for
grant at December 31, 2008 was 25,281,000.
In November 2004, our Board of Directors adopted the 2004 Consultant Stock Plan (the "2004 Plan"). The purpose of this 2004 Consultant Stock Plan is to advance our interests by helping us obtain and retain the services of persons providing consulting services upon whose judgment, initiative, efforts and/or services we are substantially dependent, by offering to or providing those persons with incentives or inducements affording such persons an opportunity to become owners of our capital stock. We reserved 2,000,000 shares of our Common Stock for awards to be made under the 2004 Plan. We filed a registration statement on Form S-8 with the SEC on November 26, 2004 to register the shares underlying the 2004 plan. The 2004 Plan is administered by a committee of two or more members of the Board of Directors or, if no committee is appointed, then by the Board of Directors. The committee, or the Board of Directors if there is no committee, determines who is
eligible to receive awards under the plan, grant awards and interpret the 2004 Plan. The number of shares under the 2004 Plan available for grant at December 31, 2008 was 500,000.



11


On May 9, 2005, our Board of Directors adopted the 2005 Equity Compensation Plan (the "2005 Plan"). The purpose of this Plan is to provide incentives to attract, retain and motivate eligible persons whose present and potential contributions are important to our success, by offering them an opportunity to participate in the our future performance through awards of Options, the right to purchase Common Stock and Stock Bonuses. We reserved 10,000,000 shares of our Common Stock for awards to be made under the 2005 Plan. The 2005 Plan is administered by a committee of two or more members of the Board of Directors or, if no committee is appointed, then by the Board of Directors. The committee, or the Board of Directors if there is no committee, determines who is eligible to receive awards under the plan, grant awards and interpret the 2005 Plan. We filed a registration statement on Form S-8 with the SEC on June 8, 2005 to register the shares underlying
the 2005 plan. The number of shares under the 2005 Plan available for grant at December 31, 2008 was 4,868,763.
Set forth in the table below is information regarding awards made through compensation plans or arrangements through December 31, 2008 the most recently completed fiscal year.

Equity Compensation Plan InformationPlan categoryNumber of securities to be issued upon exercise of outstanding options, warrants and rights
(a)Weighted-average exercise price of outstanding options, warrants and rightsNumber of securities remaining available for future issuance under equity compensation plans (excluding securitiesreflectedincolumn(a))Equity compensation plans approved by security holders---Equity compensation plans not approved by security holders30,649,763Total--30,649,763





12


Exercise prices and weighted-average contractual lives of stock options outstanding as of December 31, 2008 are as follows:

Options OutstandingOptions ExercisableExercise PriceNumber OutstandingWeighted Average Remaining Contractual LifeWeighted Average Exercise PriceNumber ExercisableWeighted Average Exercise Price$0.0128,000,0008.680.01328,000,0000.010.021,800,0004.680.0201,800,0000.020.052,625,0001.650.0502,625,0000.050.051,000,0006.580.0551,000,0000.050.205,760,0000.710.2005,760,0000.200.39250,0003.980.390250,0000.391.25200,0003.981.250200,0001.252.25110,0002.462.250110,0002.252.40500,0002.332.400500,0002.40
All options we issued through December 31, 2008 vested within ninety days from the date of grant and expire at various dates during 2008 through 2017.

We issued the following warrants at the corresponding weighted average exercise price as of December 31, 2008.

DateNumber of WarrantsExercise PriceContractual LifeNumber of Shares ExercisableOctober 11, 20073,200,000.0110 years3,200,000November 9, 2007800,000.0110 years800,0004,000,0004,000,000

ITEM 6. SELECTED FINANCIAL DATA
N/A



13


ITEM 7. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS.

The following discussion and analysis should be read in conjunction with our financial statements and accompanying notes appearing elsewhere in this Form 10-K.

OVERVIEW

We have been acquiring and licensing technologies, directing, supervising and coordinating our research and development efforts, raising capital, and initiating commercialization activities and dialogue with potential customers.

As of December 31, 2008, we had an accumulated deficit since inception, from July 31, 1992, of $52,643,000. Included in this accumulated loss are charges amounting to approximately $22,331,000 relating to the issuance of equity instruments for services. We expect operating losses to continue for the foreseeable future because we will be continuing to fund research and development efforts as well as general and administrative expenses.

We do not know if our research and development and marketing efforts will be successful, that we will ever have commercially acceptable products, or that we will achieve significant sales of any such products. We operate in an environment of rapid change in technology and we are dependent upon the services of our employees, consultants and independent contractors. If we are unable to successfully bring our technologies to commercialization, we would likely have to significantly alter our business plan and may cease operations.

YEAR ENDEDDECEMBER 31,2008COMPAREDTOYEARENDEDDECEMBER 31,2007.

REVENUES. We had no revenues for the years ended December 31, 2008 and 2007.

EXPENSES:  The following chart summarizes our operating expenses and other income and expenses as described below:

Year ended December 31,20082007Common stock issued for services57,000828,000Options issued for services1,034,000197,000Amortization of beneficial conversion
feature-1,361,000Other G&A expenses861,000847,000Total G&A expenses1,952,0003,233,000Research and development198,000210,000Operating expenses2,150,0003,443,000Other income-(14,000)Gain on sale of Novint common stock(50,000)(470,000)Net interest expense42,00055,000Net loss2,142,0003,014,000
GENERAL AND ADMINISTRATIVE. General and administrative expenses were $1,952,000 for the year ended December 31, 2008 versus general and administrative expenses of $3,233,000 for the year ended December 31, 2007, an overall decrease of $1,281,000.

General and administrative expenses were affected by common stock and options issued for services.  Excluding these items, general and administrative expenses, consisting of expenses for consultants, accounting and legal services, travel and miscellaneous expenses, remained stable.  Additionally, general and administrative costs in 2007 included costs related to the beneficial conversion feature of convertible notes.

During the year ended December 31, 2008, the Company issued 1,600,000 shares of common stock for services for a total value of $57,000.

In the first quarter of 2008, general and administrative expenses included a grant of options for 18,000,000 shares of common stock with an exercise price of $0.013 to our former CEO and a consultant.  These options replaced 16,000,000 options previously granted with an exercise price of $0.05 per share.  The value of these options totaled $1,034,000 which was valued using the Black-Scholes option pricing model based upon the following assumptions: stock price of $0.06 at grant date; 5 year term; volatility of 144%; and discount rate of 3.18%.



14


In the fourth quarter of 2007, we issued 4,200,000 shares of common stock for services to an individual with a value of $60,900 based upon the fair value of the shares issued and issued 1,000,000 shares of common stock to an individual for services with a value of $30,000 based upon the fair value of the shares issued and issued 1,000,000 shares of common stock to an individual for services to be provided with a value of $30,000 based upon the fair value of the shares issued.  In the second quarter of 2007, we issued 35,350,317 shares of common stock to various individuals for services with values totaling $707,000 based upon the fair value of the shares issued.

In the fourth quarter of 2007, we granted warrants for 3,200,000 shares of common stock with an exercise price of $0.013 to various individuals for past services.  The value of these warrants totaled $36,444 which were valued using the Black-Scholes option pricing model based upon the following assumptions: stock price of $0.013 at grant date; 5 year term; volatility of 135%; and discount rate of 4.50%.  We also granted in the fourth quarter an officer a warrant for 800,000 shares of common stock with an exercise price of $0.013.  The value of this warrant totaled $49,768 which was valued using the Black-Scholes option pricing model based upon the following assumptions: stock price of $0.065 at grant date; 5 year term; volatility of 142%; and discount rate of 4.50%.

In the first quarter of 2007, general and administrative expenses included a grant of options for 10,000,000 shares of common stock at an exercise price of $0.014 to our former CEO and chairman for services previously provided.  The value of these options totaled $110,000 which was valued using the Black-Scholes option pricing model based upon the following assumptions: stock price of $0.014 at grant date; 5 year term; volatility of 107%; and discount rate of 4.5%.
In the fourth quarter of 2007, we issued 106,000,000 shares of common stock related to the conversion of convertible debt previously issued during 2007.  The convertible debt converted totaled $1,060,000 at which time the entire debt discount of $1,361,000 had been expensed.

NET LOSS. We reported a net loss of $2,142,000 for the year ended December 31, 2008 versus a net loss of $3,014,000 for the year ended December 31, 2007, respectively, an overall decrease in net loss of $872,000, principally resulting from the common stock and options issued for services discussed above partially offset by gains in 2007 on distribution of common stock we held in Novint Technologies, Inc. (Novint).

For the years ended December 31, 2008 and 2007, we issued 53,191 and 622,216 shares of Novint as payment of accrued liabilities and related to convertible promissory notes issued during 2007 and recorded a gain on sale of those shares of $50,000 and $470,000, respectively.

LIQUIDITY AND PLAN OF OPERATIONS

We are a development stage company and are in the technology acquisition and development phase of our operations. Accordingly, we have relied primarily upon private placements and subscription sales of stock to fund our continuing activities and acquisitions. To a limited extent, we have also relied upon borrowing from our officers.  Until we generate revenue from sales and licensing of technology, or receive a large infusion of cash from a potential strategic partner or through the efforts of an investment banker, we intend to continue to rely upon this methods and the limited sales of our shares or other assets, which has become increasingly difficult with our low share price, to fund operations during the next year.

At December 31, 2008, our significant assets include our portfolio of intellectual property relating to the various technologies, our contracts with third parties pertaining to technology development, acquisition, and licensing, and 1,075,648 shares of common stock of Novint; our cash on hand; and our strategic alliances with various scientific laboratories, educational institutions, scientists and leaders in industry and government.

We had an increase of $115,000 in cash and cash equivalents for the year ended December 31, 2008, as a result of $700,000 of cash used in operating activities offsetting net proceeds from the issuance of common stock totaling $808,000 and $7,000 cash provided in the purchase of Metallicum.

For the year ended December 31, 2008, cash used in operating activities was $700,000 compared to $537,000 used in operating activities for the year ended December 31, 2007, the increase in cash used, equal to $163,000, primarily as a result of:

·
an increase in the net loss (net of the non-cash gains on the sale of Novint in 2008 and 2007 and the 2007 non-cash financing costs related to the beneficial conversion feature of convertible notes) of $69,000;



15


·
plus a lower amount of cash generated by changes in operating assets and liabilities in 2008 equal to $162,000,
·
partially offset by the net effect of common stock and options issued for an increased amount of services in 2008 of $66,000.

Common stock and options to purchase common stock were issued for services valued at $1,091,000 for the year ended December 31, 2008 and $1,025,000 for the year ended December 31, 2007.

Stockholders equity totaled a deficit of $842,000 on December 31, 2008 and the working capital was a deficit of $1,165,000 on such date.

We do not expect any significant change in the total number of employees in the near future. We intend to continue to identify and target appropriate technologies for possible acquisition or licensing over the next 12 months, although we have no agreements regarding any such technologies as of the date hereof.

Based upon current projections, our principal cash requirements for the next 12 months consists of (1) fixed expenses, including rent, payroll, investor relations services, public relations services, bookkeeping services, graphic design services, consultant services, and reimbursed expenses; and (2) variable expenses, including technology research and development, milestone payments, intellectual property protection, utilities and telephone, office supplies, additional consultants, legal and accounting. As of December 31, 2008, we had $567,000 in cash. We intend to satisfy our capital requirements for the next 12 months by continuing to pursue private placements to raise capital, using our common stock as payment for services in lieu of cash where appropriate, borrowing as appropriate, and our cash on hand. However, we do not know if those resources will be adequate to cover our capital requirements.

During April 2008 through December 2008, we sold 42,707,000 shares of common stock for approximately $850,000 from a private placement offering.  The private placement originally provided for the offer and sale of up to 50,000,000 unregistered shares of our common stock at a price of $0.02 per share, for an aggregate offering price of $1,000,000, and allowed us to accept or reject any oversubscription.   We incurred offering costs totaling approximately $46,000 which was paid in cash.  Additionally, we issued 750,000 shares of common stock for legal services rendered as part of the private placement with a total value of approximately $16,000.

RECENTLY ISSUED ACCOUNTING STANDARDS

In December 2007, the FASB issued SFAS No. 141 (Revised 2007), Business Combinations - Revised 2007. SFAS 141 (R) provides guidance on improving the relevance, representational faithfulness, and comparability of information that a reporting entity provides in our financial reports about a business combination and its effects. SFAS 141R applies to business combinations where is the acquisition date is on or after the beginning of the first annual reporting period beginning on or after December 15, 2008. We do not expect the adoption of SFAS No. 141 to have a material impact on our consolidated financial statements.

In December 2007, the FASB issued SFAS No. 160, Noncontrolling Interests in Consolidated Financial Statements - an Amendment of Accounting Research Bulletin No. 51 (SFAS No. 160), which establishes accounting and reporting standards for ownership interests in subsidiaries held by parties other than the parent, the amount of consolidated net income attributable to the parent and to the noncontrolling interest, changes in a parents ownership interest and the valuation of retained noncontrolling equity investments when a subsidiary is deconsolidated. SFAS No. 160 also establishes reporting requirements that provide sufficient disclosures that clearly identify and distinguish between the interests of the parent and the interests of the non-controlling owners. SFAS No. 160 is effective for fiscal years, and interim periods within those fiscal years, beginning on or after December 15, 2008.  We are currently evaluating the effect of this
pronouncement on our consolidated financial statements.

In March 2008, the FASB issued SFAS No. 161, Disclosures about Derivative Instruments and Hedging Activities  an amendment of FASB Statement No. 133, (SFAS 161) as amended and interpreted, which requires enhanced disclosures about an entitys derivative and hedging activities and thereby improves the transparency of financial reporting.  Disclosing the fair values of derivative instruments and their gains and losses in a tabular format provides a more complete picture of the location in an entitys financial statements of both the derivative positions existing at period end and the effect of using derivatives during the reporting period.  Entities are required to provide enhanced disclosures about (a) how and why an entity uses derivative instruments, (b) how derivative instruments and related hedged items are accounted for under Statement 133 and its related interpretations, and (c) how derivative instruments and
related hedged items affect an entitys financial position, financial performance, and cash flows.  SFAS No. 161 is effective for financial statements issued for fiscal years and interim periods beginning after November 15, 2008.  Early adoption is permitted.  At December 31, 2008, we did not have any derivative instruments or hedging activities. Management is aware of the requirements of SFAS 161 and will disclose when appropriate.



16


In May 2008, the FASB issued SFAS No. 162, The Hierarchy of Generally Accepted Accounting Principles.  SFAS 162 will provide framework for selecting accounting principles to be used in preparing financial statements that are presented in conformity with U.S. generally accepted accounting principles (GAAP) for nongovernmental entities.  SFAS 162 will be effective 60 days following the Securities and Exchange Commissions approval of the Public Company Accounting Oversight Board (PCAOB) amendments to AU Section 411.  We do not expect the adoption of SFAS 162 will have a material impact on our financial condition or results of operation.

In May 2008, the FASB issued SFAS No. 163, Accounting for Financial Guarantee Insurance Contracts  an interpretation of FASB Statement No. 60.  SFAS 163 requires that an insurance enterprise recognize a claim liability prior to an event of default (insured event) when there is evidence that credit deterioration has occurred in an insured financial obligation.  This Statement also clarifies how Statement 60 applies to financial guarantee insurance contracts, including the recognition and measurement to be used to account for premium revenue and claim liabilities. Those clarifications will increase comparability in financial reporting of financial guarantee insurance contracts by insurance enterprises. This Statement requires expanded disclosures about financial guarantee insurance contracts. The accounting and disclosure requirements of the Statement will improve the quality of information provided to users of financial statements.  SFAS 163





 will be effective for financial statements issued for fiscal years beginning after December 15, 2008.  We do not expect the adoption of SFAS 163 will have a material impact on our financial condition or results of operation.

In November 2008, the FASB ratified the Emerging Issues Task Force (EITF) consensus on Issue No. 08-6, Equity Method Investment Accounting Considerations (EITF 08-6) which addresses certain effects of SFAS Nos. 141R and 160 on an entitys accounting for equity-method investments. The consensus indicates, among other things, that transaction costs for an investment should be included in the cost of the equity-method investment (and not expensed) and shares subsequently issued by the equity-method investee that reduce the investors ownership percentage should be accounted for as if the investor had sold a proportionate share of its investment, with gains or losses recorded through earnings. EITF 08-6 is effective of us for transactions occurring after December 31, 2008.. Company has not determined the impact that this standard would have on the consolidated financial statements.

In November 2008, the FASB ratified the EITF consensus on Issue No. 08-7, Accounting for Defensive Intangible Assets (EITF 08-7). The consensus addresses the accounting for an intangible asset acquired in a business combination or asset acquisition that an entity does not intend to use or intends to hold to prevent others from obtaining access (a defensive intangible asset). Under EITF 08-7, a defensive intangible asset would need to be accounted as a separate unit of accounting and would be assigned a useful life based on the period over which the asset diminishes in value. EITF 08-6 is effective for us for transactions occurring after December 31, 2008. We have not determined the impact that this standard would have on the consolidated financial statements.

In January 2009, the FASB issued FSP No. EITF 99-20-1, Amendments to the Impairment Guidance of EITF Issue No. 99-20 (FSP No. EITF 99-20-1). This FSP provided additional guidance with respect to how entities determine whether an other-than-temporary impairment (OTTI) exists for certain beneficial interests in a securitized transaction, such as asset-backed securities and mortgage-backed securities, that (1) do not have a high quality rating or (2) can be contractually prepaid or otherwise settled such that the holder would not recover substantially all of its investment. FSP No. EITF 99-20-1 amended EITF Issue No. 99-20 to more closely align its OTTI guidance with that of SFAS No. 115, Accounting for Certain Investment in Debt and Equity Securities. This FSP was effective for us prospectively beginning October 1, 2008. We considered this FSPs additional interpretation of EITF Issue





No. 99-20 when classifying respective additional impairments as temporary or other-than-temporary beginning with the fourth quarter of 2008. This FSP had no material impact on such classifications.

GOING CONCERN

Our independent registered public accounting firms have stated in their audit report on our December 31, 2008 and 2007 consolidated financial statements, that we have experienced recurring losses and have working capital deficit. The conditions, among others, raise substantial doubt about our ability to continue as a going concern.


17


CRITICAL ACCOUNTING POLICIES AND ESTIMATES

Our discussion and analysis of our financial condition and results of operations are based upon our consolidated financial statements, which have been prepared in accordance with accounting principles generally accepted in the United States
of America.

Use of Estimates

The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the amount of assets and liabilities and disclosures of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses during the reporting period. A significant estimate includes the carrying value of our patents, fair value of our common stock, assumptions used in calculating the value of stock options, depreciation and amortization.

Impairment of Long-Lived Assets:

We assess the impairment of our long-lived assets periodically in accordance with the provisions of Statement of Financial Accounting Standards ("SFAS") 144, "Accounting for the Impairment and Disposal of Long-Lived Assets". Whenever events or changes in circumstances indicate that the carrying amounts of long-lived assets may not be recoverable, we will compare undiscounted net cash flows estimated to be generated by those assets to the carrying amount of those assets. When these undiscounted cash flows are less than the carrying amounts of the assets, we will record impairment losses to write the asset down to fair value, measured by the discounted estimated net future cash flows expected to be generated from the assets. To date there has been no impairment.
Investments

Patents

Intangible assets consist of patent licensing costs incurred to date. Patents consist of mid-range fuel cell and the micro fuel cell technologies that are being amortized using the straight-line method over the estimated economic useful life of 10 years. We have capitalized $2,080,000 in patent licensing costs as of December 31, 2008. Amortization expense charged to operations was $194,000 and $208,000 for the years ended December 31, 2008 and 2007, respectively. At December 31, 2008 these parents were fully amortized.

License Agreements

In 2008,  we obtained licenses to the rights of certain patents regarding nano-structured materials developed by another company as a result of the acquisition of Metallicum. The purchase price paid for these licenses was $305,000, which represents its fair value.  We obtained an exclusive license on two patents and a non-exclusive license on the third patent. The value attributable to license agreements is being amortized over the period of its estimated benefit period of 10 years. At December 31, 2008, accumulated amortization was $15,000. Under the terms of the agreement, we may be required to pay royalties, as defined, to the licensors.

Investments

Available-for-Sale Investments


Investments that we designate as available-for-sale are reported at fair value, with unrealized gains and losses, net of tax, recorded in accumulated other comprehensive income (loss). We determine the cost of the investment sold based on the specific identification method. Our available-for-sale investments include Marketable equity securities.  We acquire these equity investments for the promotion of business and strategic objectives. We record  the realized gains or losses on the sale or exchange of marketable equity securities in gains (losses) on other equity investments, net

Convertible Notes Payable:

During 2007, we have issued convertible debt securities with non-detachable conversion features. The values assigned to the warrants and embedded conversion feature of the Debentures followed the guidance of the EITF Issue No. 98-5, Accounting for Convertible Securities with Beneficial Conversion Features or Contingently Adjustable Conversion Ratios, EITF 00-19: Accounting for Derivative Financial Instruments Indexed to, and Potentially Settled in, a Companys Own Stock, FAS No. 150, Accounting for Certain Financial Instruments with Characteristics of both Liabilities and Equity and EITF Issue No. 00-27, Application of Issue No. 98-5 to Certain Convertible Instruments of the FASBs Emerging Issues Task Force. The debt discount associated with the Warrants and embedded conversion feature is amortized to interest expense over the life of the Debenture or upon earlier conversion of the Debenture using the effective
yield method.



18


Stock-Based Compensation:

On January 1, 2006, we adopted SFAS 123 (revised 2004), Share-Based Payment (SFAS 123(R)), which requires the measurement and recognition of compensation expense for all share-based awards made to employees and directors, including employee stock options and shares issued through its employee stock purchase plan, based on estimated fair values. In March 2005, the Securities and Exchange Commission issued Staff Accounting Bulletins No. 107 and 110 (SAB 107 and SAB 110) relating to SFAS 123(R). We have applied the provisions of SAB 107 and SAB 110 in our adoption of SFAS 123(R). We adopted SFAS 123(R) using the modified prospective transition method, which requires the application of the accounting standard as of the beginning in 2006. Our financial statements as of and for the year ended December 31, 2008 and 2007 reflect the impact of SFAS 123(R). In accordance with the modified prospective transition method,  Our
financial statements for prior periods do not include the impact of SFAS 123(R).

The estimated fair value of grants of stock options and warrants to our nonemployees is charged to expense, if applicable, in the financial statements. These options vest in the same manner as the employee options granted under each of the option plans as described above. As of December 31, 2008 and 2007, we recorded compensation/service expense of $1,034,000 and $197,000, respectively.

OFF BALANCE SHEET ARRANGEMENTS
We have not entered into any off-balance sheet arrangements that have or are reasonably likely to have a current or future effect on our financial condition, changes in financial condition, revenues or expenses, results of operations liquidity, capital expenditures or capital resources and would be considered material to investors.

ITEM 7A. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK
N/A


19


ITEM 8. FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

FINANCIAL STATEMENTS
REPORTS OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRMF-2-3CONSOLIDATED BALANCE SHEETS AS OF DECEMBER 31, 2008 AND 2007F-4CONSOLIDATED STATEMENTS OF OPERATIONS AND OTHER COMPREHENSIVE INCOME FOR THE YEARS ENDED DECEMBER 31, 2008 AND 2007 AND FOR THE PERIOD FROM 
JULY 31, 1992 (INCEPTION) THROUGH DECEMBER 31, 2008F-5CONSOLIDATED STATEMENTS OF STOCKHOLDERS EQUITY (DEFICIT)
FOR THE PERIODS FROM JULY  31, 1992 (INCEPTION) THROUGH DECEMBER 31, 2008F-6CONSOLIDATED STATEMENTS OF CASH FLOWS FOR THE YEARS ENDED 
DECEMBER 31, 2008 AND 2007 AND FOR THE PERIOD FROM 
JULY 31, 1992 (INCEPTION) THROUGH DECEMBER 31, 2008F-15NOTES TO CONSOLIDATED FINANCIAL STATEMENTSF-16

F-1


REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM To the Board of Directors and
Stockholders Manhattan Scientifics, Inc. New York, New York We have audited the accompanying balance sheet of Manhattan Scientifics, Inc. (a development stage enterprise) (the Company) as of December 31, 2008, and the related statement of operations, stockholders deficit, and cash flows for year ended December 31, 2008. The financial statements for the period from inception (July 31, 1992 to December 31, 2007) were audited by other auditors whose reports included an explanatory paragraph that expressed substantial doubt about the Companys ability to continue as a going concern.  The financial statements for the period from inception (July 31, 1992 to December 31, 2007) include total revenues and net loss of $856,000 and $45,496,000, respectively. Our opinion on the statements of operations, stockholders deficit and cash flows for the period from inception (July 31, 1992 to December 31, 2008), insofar as it relates to amounts for prior periods
through December 31, 2007, is based solely on the report of the other auditors.  Manhattan Scientifics, Inc.s management is responsible for these financial statements. Our responsibility is to express an opinion on these financial statements based on our audits. We conducted our audit in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. The company is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. Our audit included consideration of internal control over financial reporting as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the companys internal control over financial reporting. Accordingly, we express no such opinion. An audit also includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant





 estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audit provides a reasonable basis for our opinion. In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of Manhattan Scientifics, Inc. as of December 31, 2008 and the results of its operations and its cash flows for year ended December 31, 2008, and for the period from inception (July 31, 1992 to December 31, 2008) in conformity with accounting principles generally accepted in the United States of America. The  accompanying  financial  statements  have been  prepared  assuming that the
company will continue as a going  concern.   As  discussed in Note 2 to the
financial statements,  the Company has experienced recurring losses and negative
cash   flows   from   operations   and  has  both  a  working   capital   and  a
stockholders  deficit at December 31, 2008, that raise  substantial  doubt
about its ability to continue as a going concern.   Managements plans
in regard to these  matters are also  described in Note 2.   The  financial
statements do not include any adjustments  that might result from the outcome of
this uncertainty.  PMB Helin Donovan San Francisco, CA May 4, 2009    F-2


AJ. ROBBINS, P.C. CERTIFIED PUBLIC ACCOUNTANTS
216 SIXTEENTH STREET
SUITE 600
DENVER, COLORADO 80202   REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM   To the Board of Directors and Stockholders Manhattan Scientifics, Inc.
New York, New York We have audited the accompanying consolidated balance sheet of Manhattan Scientifics, Inc. (a development stage enterprise) (the Company) as of December 31, 2007, and the related consolidated statements of operations, changes in stockholders' equity (capital deficit), and cash flows for the year then ended.  These consolidated financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these consolidated financial statements based on our audit. We conducted our audit in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement. The Company is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. Our audit included consideration of internal control over financial reporting as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Companys internal control over financial reporting. Accordingly, we express no such opinion.  An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the consolidated financial statements. An audit also includes assessing the accounting
principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audit provides a reasonable basis for our opinion. In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial position of Manhattan Scientifics, Inc. as of December 31, 2007, and the results of its operations and its cash flows for the year then ended, in conformity with generally accepted accounting principles in the United States of America. The accompanying financial statements have been prepared assuming that the Company will continue as a going concern. As discussed in Note 2 to the financial statements, the Company has experienced recurring losses and negative cash flows from operations and has both a working capital and a capital deficit at December 31, 2007, that raise substantial doubt about its ability to continue as a going concern. Management's plans in regard to these matters are also described in Note 2. The financial statements do not include any adjustments that might results from the outcome of this uncertainty. AJ. ROBBINS, P.C.
CERTIFIED PUBLIC ACCOUNTANTS  Denver, Colorado January 29, 2009     F-3   MANHATTAN SCIENTIFICS, INC. AND SUBSIDIARIES(a development stage enterprise)CONSOLIDATED BALANCE SHEETS
ASSETSDecember 31, 2008December 31, 2007Current assets:Cash and cash equivalents$567,000452,000Investments-available for sale129,000-Prepaid expenses and other assets-44,000Total current assets696,000496,000Investments2,0002,000Intellectual property, net290,000-Patents, net of accumulated amortization of $2,080,000 and $1,886,000, respectively-194,000Other asset31,00030,000Total assets$1,019,000722,000LIABILITIESCurrent liabilitiesAccounts payable and accrued expenses$281,000364,000Accrued interest and expenses - related parties552,000403,000Note payable to related party545,000545,000Note payable to former officers450,000450,000Convertible note payable - other33,00033,000Total current liabilities1,861,0001,795,000Commitments and Contingencies:STOCKHOLDERS DEFICITCapital stock $.001 par valuePreferred, authorized 1,000,000 sharesSeries A convertible, redeemable, 10 percent cumulative, authorized
182,525, shares; issued and outstanding - none--Series B convertible,  authorized 250,000 shares; 49,999 shares issued and outstanding--Series C convertible, redeemable, authorized 14,000 shares;issued and outstanding - none--Common, authorized 500,000,000 shares, 378,977,926 and 318,545,000 shares issued,  and outstanding, respectively379,726319,000Additional paid-in-capital51,292,27449,109,000Other accumulated comprehensive income129,000-Deficit accumulated during the development stage(52,643,000)(50,501,000)Total Stockholders deficit(842,000)(1,073,000)TOTAL LIABILITIES AND STOCKHOLDERS DEFICIT$1,019,000722,000


The accompanying notes are an integral part of these consolidated financial statements. F-4    MANHATTAN SCIENTIFICS, INC. AND SUBSIDIARIES(a development stage enterprise)CONSOLIDATED STATEMENTS OF OPERATIONS AND OTHER COMPREHENSIVE INCOME (LOSS)
PERIOD FROMJULY 31, 1992YEAR ENDED(INCEPTION)DECEMBER 31,THROUGH20082007December 31, 2008Revenue$
-$
-
-$
856,000Operating costs and expenses:General and administrative1,952,0003,233,00044,687,000Research and development198,000210,0009,020,000Impairment charge of certain patents--189,000Total operating costs and expenses2,150,0003,443,00053,896,000Loss from operations before other income and expenses(2,150,000)(3,443,000)(53,040,000)Other income and expenses:Gain from sale of equity interest--885,000Gain on settlement of NMXS.com option--50,000Gain on legal settlement-14,00014,000Proceeds from sale of NMXS.com common stock--393,000Gain from sale of Novint Technologies Inc. common stock50,000470,0001,984,000Gain on issuance of investor common stock--531,000Contract revenue--3,741,000Interest and other expenses(50,000)(61,000)(1,132,000)Interest income8,0006,000192,000Equity in losses of investees--(1,243,000)Gain / (loss) on disposal of equipment--(13,000)NET LOSS(2,142,000)(3,014,000)(47,638,000)Other comprehensive incomeUnrealized gain on available for sale
investments129,000-129,000OTHER COMPREHENSIVE LOSS$

(2,013,000)$   (3,014,000)(47,509,000)BASIC AND DILUTED LOSS PER COMMON SHARE:Weighted average number of common shares outstanding328,469,378249,567,399Basic and diluted loss per common share$
(0.01)$
(0.01)
The accompanying notes are an integral part of these consolidated financial statements.
F-5


MANHATTAN SCIENTIFICS, INC. AND SUBSIDARIES (a development stage enterprise)  Consolidated Statements of Stockholders Equity ( Deficit) For the Cumulative Period from July 31, 1992 (Inception) Through December 31, 2007    Series A Preferred StockPreferred Stock 
$.001 Par Value 
Series B
Shares             AmountPreferred Stock 
$.001 Par Value 
Series C
Shares             AmountCommon Stock 
$.001 Par Value
Shares             AmountAdditional Paid-in
CapitalDeferred
Comp.Amounts Receivable From
Stockholders
Other accumulated comprehensive income
Deficit Accumulated
During the Develop.
StageTreasury
StockTotalInitial issuance of shares to founders on contribution of intangible assets at historic cost basis$                 --$                 --$                 -14,391,627$     $14,500$            500$                 -$                 -
$                  -
$                 -$                 -$              15,000Additional founders' contribution40,000(40,000)

-Issuance of 1,037,000 shares of Series A preferred stock, net of issuance costs10,0001,020,000(286,000)

744,000Net loss


$(543,000)(543,000)Balance, March 31, 199310,00014,391,62714,5001,060,500(326,000)

(543,000)216,000Issuance of shares to investor at approximately $.21 per share14,391,62714,5002,985,500

3,000,000Issuance of shares on exercise of options479,7201,00049,000

50,000Services performed in exchange for Series A preferred stock issued in fiscal 1993
127,000

127,000Net loss


(2,292,000)(2,292,000)Balance, March 31, 199410,00029,262,97430,0004,095,000(199,000)

(2,835,000)1,101,000Services performed for Series A preferred stock issued in fiscal 1993
159,000

159,000Issuance of shares at approximately $.52 per share345,399182,000

182,000Net loss


(2,250,000)(2,250,000)Balance, December 31, 199410,00029,608,37330,0004,277,000(40,000)

(5,085,000)(808,000)Issuance of 163,000 shares of Series A preferred stock2,000161,000

163,000Write-off of amounts receivable from stockholders(40,000)40,000

-Net loss


(972,000)(972,000)Balance, December 31, 199512,00029,608,37330,0004,398,000-

(6,057,000)(1,617,000)Issuance of shares upon exercise of option for $15,00014,391,62714,0001,000

15,000Net loss


(284,000)(284,000)Balance, December 31, 199612,00044,000,00044,0004,399,000-

(6,341,000)(1,886,000)  The accompanying notes are an integral part of these consolidated financial statements. F-6   MANHATTAN SCIENTIFICS, INC. AND SUBSIDARIES
(a development stage enterprise)

Consolidated Statements of Stockholders Equity ( Deficit)
For the Cumulative Period from July 31, 1992 (Inception) Through December 31, 2007



Series A Preferred StockPreferred Stock 
$.001 Par Value 
Series B
Shares             AmountPreferred Stock 
$.001 Par Value 
Series C
Shares             AmountCommon Stock 
$.001 Par Value
Shares             AmountAdditional Paid-in
CapitalDeferred
Comp.Amounts Receivable From
Stockholders
Other accumulated comprehensive income
Deficit Accumulated
During the Develop.
StageTreasury
StockTotalBalance, December 31, 199612,00044,000,000$44,0004,399,000

(6,341,000)$(1,886,000)Purchase and retirement of 1,200,000 shares of Series A preferred stock(12,000)(58,000)

(70,000)Purchase of 7,195,814 treasury shares of common stock for $15,000


(15,000)(15,000)Net loss/comprehensive loss


(335,000)(335,000)Balance, December 31, 1997-44,000,00044,0004,341,000-

(6,676,000)(15,000)(2,306,000)Purchase of 7,195,813 treasury shares of common stock for $15,000


(15,000)(15,000)Special distribution of 14,391,627 shares of common stock to Projectavision, Inc.346,000

30,000376,000Shares deemed issued in connection with reverse merger11,000,00011,000(11,000)Issuance of 182,525 shares of Series A preferred stock and warrants exercisable into 750,000 shares of common stock at an exercise price of $.10 per share in exchange for note payable of $1,500,000 and accrued interest of $330,000 including deemed dividend in connection with beneficial conversion feature of preferred stock2,850,000

(1,020,000)1,830,000Issuance of shares at $.20 per share, net of issuance costs5,000,0005,000970,000

975,000Issuance of shares to purchase intangible assets7,200,0007,0001,433,000

1,440,000Issuance of shares at $.58 per share for consulting services1,000,0001,000579,000

580,000Issuance of warrants on February 10, 1998 to purchase 2,000,000 shares of common stock exercisable at $.75 per share at fair value for services resulting from cashless exercise feature660,000

660,000Issuance of shares at $.18 per share275,00050,000

50,000Issuance of shares on conversion of 182,525 shares of Series A preferred stock9,435,40510,000(10,000)Issuance of shares at $.05 per share20,340,00020,000997,000

1,017,000Issuance of stock options and warrants at fair value for services2,165,000

2,165,000Net loss/comprehensive loss


(4,580,000)(4,580,000)Balance, December 31, 199898,250,40598,00014,370,000

(12,276,000)-2,192,000
The accompanying notes are an integral part of these consolidated financial statements.
F-7

MANHATTAN SCIENTIFICS, INC. AND SUBSIDARIES
(a development stage enterprise)

Consolidated Statements of Stockholders Equity ( Deficit)
For the Cumulative Period from July 31, 1992 (Inception) Through December 31, 2007



Series A Preferred StockPreferred Stock 
$.001 Par Value 
Series B
Shares             AmountPreferred Stock 
$.001 Par Value 
Series C
Shares             AmountCommon Stock 
$.001 Par Value
Shares             AmountAdditional Paid-in
CapitalDeferred
Comp.Amounts Receivable From
Stockholders
Other accumulated comprehensive income
Deficit Accumulated
During the Develop.
StageTreasury
StockTotalBalance, December 31, 199898,250,405$98,000$14,370,000

$(12,276,000)$2,192,000Issuance of shares in satisfaction of accrued expenses78,00015,000

15,000Issuance of shares at $.49 per share for consulting services10,0005,000

5,000Issuance of shares at $.49 per share to purchase furniture and fixtures100,00049,000

49,000Issuance of shares at market prices as consulting services were performed17,26915,000

15,000Issuance of shares to purchase intangible assets1,000,0001,000999,000

1,000,000Issuance of shares at $1.25 per share for services1,6002,000

2,000Issuance of stock options Immediately exercisable at fair value for services6,572,000

6,572,000Issuance of warrants on February 10, 1998 to purchase 2,000,000 shares of common stock exercisable at $.75 per share for consulting services resulting from notification of warrant holder of intent to exercise1,090,000

1,090,000Shares issuable at $1.27 per share in connection with note payable191,000

191,000Issuance of shares on exercise of 100,000 options at $.20 per share100,00020,000

20,000Issuance of Series B convertible preferred shares at $6.00 per share including deemed dividend in connection with beneficial conversion feature of preferred stock245,1652,942,000

(1,471,000)1,471,000Issuance of shares at $.75 per share533,0001,000399,000

400,000Issuance of shares at $.75 per share515,0001,000385,000

386,000Issuance of shares at market price for service4,942Issuance of common stock to Equilink, LLC on exercise of cashless warrants1,076,9231,000(1,000)Net loss/comprehensive loss


(9,800,000)(9,800,000)Balance, December 31, 1999245,165101,687,139102,00027,053,000

(23,547,000)3,608,000
The accompanying notes are an integral part of these consolidated financial statements.
F-8

MANHATTAN SCIENTIFICS, INC. AND SUBSIDARIES
(a development stage enterprise)

Consolidated Statements of Stockholders Equity ( Deficit)
For the Cumulative Period from July 31, 1992 (Inception) Through December 31, 2007




Series A Preferred StockPreferred Stock 
$.001 Par Value 
Series B
Shares             AmountPreferred Stock 
$.001 Par Value 
Series C
Shares             AmountCommon Stock 
$.001 Par Value
Shares             AmountAdditional Paid-in
CapitalDeferred
Comp.Amounts Receivable From
StockholdersOther accumulated comprehensive incomeDeficit Accumulated
During the Develop. StageTreasury
StockTotalBalance, December 31, 1999245,165101,687,139$102,000$27,053,000$(23,547,000)$3,608,000Shares issued of Series preferred shares at $100.00 per share including deemed dividend in connection with beneficial conversion feature of preferred stock14,0002,199,000(1,400,000)799,000Issuance of shares in connection with Series C preferred stock private placement investment700,0001,000600,000601,000Shares issuable at $2.23 per share in connection with research and development license agreement1,115,000(1,115,000)Issuance of shares at market price for services11,08324,00024,000Issuance of options at market value for services229,000229,000Issuance of options for 100,000 shares @$.40 per share for services/amortization of deferred comp.113,000113,000Issuance of stock options in connection with deferred compensation agreement425,000(425,000)Issuance shares to purchase furniture and fixtures10,50040,00040,000Issuance of shares in connection with Series C preferred stock private placement10,000Issuance of shares at $1.25 per share1,600,0502,0001,998,0002,000,000Conversion of Series B preferred stock to common(60,000)600,000Issuance of shares at market price for services51,000102,000102,000Shares issuable at market price for services88,00088,000Net loss/comprehensive loss(4,736,000)(4,736,000)Balance, December 31, 2000185,16514,000104,669,772105,00033,873,000(312,000)(30,798,000)2,868,000Issuance of shares in connection with private placement offerings1,097,5001,098694,000695,098Issuance of shares upon conversion of Series B preferred stock(100,166)1,001,6601,0021,002Issuance of shares upon conversion of Series C preferred stock(14,000)2,800,0002,8002,800Issuance of shares upon exercise of stock options15,000153,0003,015Issuance of shares to acquire Teneo Computing Inc.1,400,0001,400784,000785,400Issuance of shares to purchase 42% of Novint Technologies, Inc.1,000,0001,000560,000561,000Issuance of shares for services at fair market value3,388,0971,7432,138,0002,139,743Exercise of warrants issued for services942,281942782,000782,942Issuance of stock options for services250,000250,000Amortization of deferred compensation85,00085,000Net loss/comprehensive loss(6,662,000)(6,662,000)Balance, December 31, 200184,999-116,314,310115,00039,084,000(227,000)(37,460,000)1,512,000
The accompanying notes are an integral part of these consolidated financial statements.
F-9


MANHATTAN SCIENTIFICS, INC. AND SUBSIDARIES
(a development stage enterprise)

Consolidated Statements of Stockholders Equity ( Deficit)
For the Cumulative Period from July 31, 1992 (Inception) Through December 31, 2007





Series A Preferred StockPreferred Stock 
$.001 Par Value 
Series B
Shares             AmountPreferred Stock 
$.001 Par Value 
Series C
Shares             AmountCommon Stock 
$.001 Par Value
Shares             AmountAdditional Paid-in
CapitalDeferred
Comp.Amounts Receivable From
StockholdersOther accumulated comprehensive incomeDeficit Accumulated
During the Develop.
StageTreasury
StockTotalBalance, December 31, 200184,999116,314,310$115,000$39,084,000$(227,000)$(37,460,000)$1,512,000Issuance of shares in connection with private placement offering850,0001,000253,000254,000Issuance of shares for the payment of research and development75,00030,00030,000Issuance of shares at market for services rendered5,0002,0002,000Issuance of shares in connection with private placement offering285,700100,000100,000Issuance of shares for the payment of research and development975,0001,000360,000361,000Issuance of shares at market for services rendered620,0001,000203,000204,000Issuance of shares in connection with private placement offering400,000100,000100,000Issuance of shares upon conversion of Series B preferred stock(10,000)100,000Issuance of shares  at  market for services rendered500,0001,000135,000136,000Issuance of shares for the payment of research and development150,00040,00040,000Issuance of shares in connection with private placement offering600,0001,000149,000150,000Issuance of shares at market for services rendered25,2778,0008,000Issuance of shares in connection with private placement offering1,000,0001,00099,000100,000Issuance of shares in connection with private placement offering300,00030,00030,000Issuance of shares at market for services rendered247,93459,00059,000Issuance of shares at market for services rendered1,285,3011,000169,000170,000Issuance of shares at market for services rendered394,00039,00039,000Issuance of shares at market for services rendered60,0008,0008,000Issuance of shares at market for services rendered75,0007,0007,000Amortization of deferred compensation85,00085,000Net loss/comprehensive loss(4,028,000)(4,028,000)Balance, December 31, 200274,999124,262,522122,00040,875,000(142,000)(41,488,000)(633,000)
The accompanying notes are an integral part of these consolidated financial statements.
F-10

MANHATTAN SCIENTIFICS, INC. AND SUBSIDARIES
(a development stage enterprise)

Consolidated Statements of Stockholders Equity ( Deficit)
For the Cumulative Period from July 31, 1992 (Inception) Through December 31, 2007



Series A Preferred StockPreferred Stock 
$.001 Par Value 
Series B
Shares             AmountPreferred Stock 
$.001 Par Value 
Series C
Shares             AmountCommon Stock 
$.001 Par Value
Shares             AmountAdditional Paid-in
CapitalDeferred
Comp.Amounts Receivable From
Stockholders
Other accumulated comprehensive income
Deficit Accumulated
During the Develop.
StageTreasury
StockTotalBalance, December 31, 200274,999124,262,522122,00040,875,000(142,000)

(41,488,000)(633,000)Issuance of shares at market for services rendered1,000,0001,00070,000

71,000Issuance of shares in connection with private placement offering1,000,0001,00040,000

41,000Issuance of shares at market for services rendered125,0001,000

1,000Issuance of shares at market for services rendered1,000,0001,00050,000

51,000Issuance of shares at market for services rendered300,0001,00020,000

21,000Issuance of shares at market for services rendered2,000,0002,000100,000

102,000Issuance of shares at market for services rendered2,000,0002,00079,000

81,000Issuance of shares at market for services rendered1,000,0001,00049,000

50,000Issuance of shares at market for services rendered400,0001,00020,000

21,000Issuance of shares at market for services rendered20,0001,000

1,000Issuance of shares at market for services rendered20,0001,000

1,000Issuance of shares at market for services rendered20,0001,000

1,000Issuance of shares at market for services rendered400,0001,00016,000

17,000Issuance of shares at market for services rendered500,0001,00025,000

26,000Issuance of shares at market for services rendered1,011,0001,00040,000

41,000Issuance of shares at market for services rendered250,00010,000

10,000Issuance of shares at market for services rendered260,00010,000

10,000Issuance of shares at market for services rendered250,00010,000

10,000Issuance of shares at market for services rendered125,0005,000

5,000Issuance of shares at market for services rendered600,0001,00025,000

26,000Issuance of shares at market for services rendered500,0001,00020,000

21,000Issuance of shares at market for services rendered100,0004,000

4,000Issuance of shares at market for director/officer services rendered13,500,00014,000392,000

406,000Issuance of shares at market for director/officer services rendered5,250,0005,000153,000

158,000Issuance of shares upon cancelation of stock options2,750,0003,00082,000

85,000Issuance of shares at market for director/officer services rendered1,750,0002,00052,000

54,000Issuance of shares upon cancelation of stock options990,0001,00030,000

31,000Issuance of shares at market for director/officer services rendered2,250,0002,00065,000

67,000Issuance of shares at market for director/officer services rendered1,000,0001,00049,000

50,000The accompanying notes are an integral part of these consolidated financial statements.
F-11


Year ended December 31, 2003 (continued)Issuance of shares at market for director/officer services rendered250,00012,000

12,000Issuance of shares at market for director/officer services rendered250,00012,000

12,000Issuance of shares at market for director/officer services rendered1,000,0001,00050,000

51,000Issuance of shares at market for director/officer services rendered250,00012,000

12,000Issuance of shares at market for director/officer services rendered250,00012,000

12,000Issuance of shares upon cancelation of stock options500,0001,00030,000

31,000Issuance of shares at market for services rendered50,0002,000

2,000Issuance of shares at market for services rendered1,000,0001,00050,000

51,000Issuance of shares at market for services rendered35,0002,000

2,000Issuance of shares at market for services rendered500,0001,00025,000

26,000Issuance of shares upon cancelation of stock options500,0001,00030,000

31,000Issuance of shares upon cancelation of stock options675,0001,00040,000

41,000Issuance of shares for options exchanged200,000Issuance of shares for options exchanged100,000Issuance of shares for options exchanged200,000Issuance of shares for options exchanged250,000Issuance of shares for options exchanged130,000Issuance of shares for options exchanged100,000Issuance of shares for options exchanged200,000Issuance of shares for options exchanged100,000Conversion of series B preferred stock to common(25,000)250,000Issuance of shares at market for services rendered250,00021,000

21,000Issuance of shares at market for services rendered335,0001,00020,000

21,000Stock options issued for services113,000

113,000Amortization of deferred compensation
142,000

142,000Net loss/comprehensive loss


(2,569,000)(2,569,000)Balance, December 31, 200349,999172,008,522172,00042,726,000-

(44,057,000)(1,159,000)The accompanying notes are an integral part of these consolidated financial statements.
F-12


Balance, December 31, 200349,999172,008,522$172,000$42,726,000-

$(44,057,000)$(1,159,000)Issuance of shares at market for services rendered4,833,0005,000487,000

492,000Issuance of shares on exercise of options866,000126,000

126,000Issuance of shares for the payment of notes payable641,2741,00047,000

48,000Issuanceofwarrantsinconnectionwithnotepayable214,000

214,000Net loss/comprehensive loss


(1,517,000)(1,517,000)Balance December 31, 200449,999178,348,796178,00043,600,000

(45,574,000)(1,796,000)Stock options issued in exchange for previously issued options46,000

46,000Issuance of shares at market for services rendered1,023,0001,00064,000

65,000Issuance of shares in satisfaction of accrued expenses4,458,2374,000238,000

242,000Net loss/comprehensive loss


(219,000)(219,000)Balance December 31, 200549,999183,830,033183,00043,948,000

(45,793,000)(1,662,000)Issuance of shares at market for services rendered1,640,0002,00086,000

88,000Issuance of shares in satisfaction of note payable795,3241,00044,000

45,000Issuance of shares for services rendered by Board of Directors13,000,00013,800766,200

780,000Issuance of shares in satisfaction of accrued expenses1,184,2201,20057,800

59,000Net loss/comprehensive loss


(1,694,000)(1,694,000)Balance December 31, 2006-49,999$                 --$                 -200,449,577$     201,000$44,902,000$                 -

$                 -$(47,487,000)$                 -$      (2,384,000)
The accompanying notes are an integral part of these consolidated financial statements.
F-13

MANHATTAN SCIENTIFICS, INC. AND SUBSIDARIES
(a development stage enterprise)

Consolidated Statements of Stockholders Equity ( Deficit)
For the Cumulative Period from July 31, 1992 (Inception) Through December 31, 2007













Series A Preferred StockPreferred Stock 
$.001 Par Value 
Series B
Shares             AmountPreferred Stock 
$.001 Par Value 
Series C
Shares             AmountCommon Stock 
$.001 Par Value
Shares             AmountAdditional Paid-in
CapitalDeferred
Comp.Amounts Receivable From
Stockholders
Other accumulated comprehensive income
Deficit Accumulated
During the Develop.
StageTreasury
StockTotalBalance December 31, 2006-49,999$                 --$                 -200,449,577$     201,000$44,902,000$                 -$                 -
$                 -
$(47,487,000)$                 -$      (2,384,000)Issuance of shares at market for services rendered41,550,31742,000786,000

828,000Issuance of shares in satisfaction of note payable14,200,10614,00057,000

71,000Issuance of shares related to conversion of convertible notes106,000,000106,000954,000

1,060,000Purchase and retirement of common shares and warrants for 10,000,000 shares of common share(43,655,000)(44,000)(171,000)

(215,000)Settlement of related party debt1,416,000

1,416,000Beneficial conversion feature related to convertible notes968,000

968,000Issuance of stock options197,000

197,000Net loss/comprehensive loss


(3,014,000)(3,014,000)Balance December 31, 2007-49,999$                 --$                 -318,545,000$     319,000$49,109,000$                 -$                 -

$(50,501,000)$                 -$      (1,073,000)Issuance of shares at market for services rendered1,600,0001,60055,400

57,000Issuance of shares in satisfaction of accrued exp.1,125,9261,12643,874

45,000Issuance of shares related to acquisition of Metallicum, Inc.15,000,00015,000285,000

300,000Issuance of shares for cash, net of offering costs of $46,00042,707,00043,000765,000

808,000Issuance of stock options1,034,000

1,034,000Other comprehensive income-gain on available for sale securities

129,000
129,000Net loss


(2,142,000)(2,142,000)Balance December 31, 2008-49,999$                 --$                 -378,977,926$     379,726$51,292,274$                 -$                 -
$      129,000
$(52,643,000)$                 -$      (842,000)


The accompanying notes are an integral part of these consolidated financial statements.
F-14


MANHATTAN SCIENTIFICS, INC. AND SUBSIDIARIES(a development stage enterprise)CONSOLIDATED STATEMENTS OF CASH FLOWSPERIOD FROMJULY 31, 1992YEARENDED DECEMBER 31,(INCEPTION) THROUGH20082007December 31, 2008CASH FLOWS FROM (TO) OPERATING ACTIVITIES:Net loss$   (2,142,000)$   (3,014,000)$   (47,638,000)Adjustments to reconcile net loss to net cash used in operating activities:Gain on sale of investments(50,000)(470,000)(2,373,000)Gain on settlement of NMXS.com option--(50,000)Gain from sale of equity interest in Horizon--(885,000)Gain on issuance of investee common stock--(531,000)Common stock issued for services57,000828,0007,998,000Preferred stock issued for services--598,000Stock options issued for services1,034,000197,00011,072,000Cashless stock option exercise--126,000Warrants issued for services--2,556,000Convertible note issued for services-1,000108,000Financing costs payable with common stock--191,000Financing costs related to beneficial conversion feature of
convertible notes-1,361,0001,361,000Loss of equity investee--1,207,000Amortization of technology license15,000-552,000Amortization of patents194,000208,0002,080,000Loss on disposal of equipment--28,000Impairment charge of certain patents--189,000Impairment charge on property and equipment--8,000Depreciation-2,0001,127,000Changes in:Prepaid expenses and other assets44,000(12,000)225,000Accounts payable and accrued expenses(1,000)466,0003,357,000Accrued interest and expenses - related parties149,000(104,000)552,000Net cash provided by (used in) operating activities;(700,000)(537,000)(18,142,000)CASH FLOWS FROM (TO) INVESTING ACTIVITIES:Purchase of equipment--(432,000)Purchase of investment--(100,000)Cash acquired from purchase of Metallicum7,000-7,000Proceeds from sale of equipment--18,000Proceeds from sale of equity interest--885,000Proceeds from settlement of NMXS.com--50,000Proceeds received from sale of investment--1690,000Net cash provided by (used in) investing activities7,000-2,118,000   The accompanying notes are an integral part of these consolidated financial statements. F-15   MANHATTAN SCIENTIFICS, INC. AND SUBSIDIARIES(a development stage enterprise)CONSOLIDATED STATEMENTS OF CASH FLOWS (Continued)PERIOD FROMJULY 31, 1992YEARENDED DECEMBER 31,(INCEPTION) THROUGH20082007December 31, 2008CASH FLOWS FROM (TO) FINANCING ACTIVITIES:Repurchase of common stock-(215,000)(315,000)Note payable to stockholders--2,374,000Proceeds from convertible notes payable-1,060,0001,060,000Proceeds from note payable  other--634,000Repayment of note payable  other--(435,000)Repayment of note payable to officers-(5,000)(530,000)Net proceeds from issuance of preferred stock--3,569,000Proceeds from issuance of common stock, net of offering costs of $46,000808,000-10,379,000Loan repayment to preferred stockholder--(148,000)Capital lease payments--(13,000)Return of security deposit--16,000Net cash provided by (used in) financing activities808,000840,00016,591,000NET (DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS115,000303,000567,000Cash and cash equivalents, beginning of period452,000149,000-CASH AND CASH EQUIVALENTS, END OF PERIOD$    567,000$    452,000$     567,000SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:Interest paid$                -$                -$     111,000SUPPLEMENTAL DISCLOSURES OF NONCASH INVESTING AND FINANCING ACTIVITIES:Fixed assets contributed to the company in exchange for Series A preferred stock--$
45,000Issuance of 14,391,627 common shares to acquire intangible assets--$
15,000Special distribution of 14,391,627 shares of common stock tostockholder in settlement of stockholder advances--$
376,000Issuance of 7,200,000 common shares to acquire intangible assets--$
1,440,000Issuance of Series A preferred stock and warrants in settlementof note payable and accrued interest--$
1,830,000Issuance of 1,000,000 common shares to acquire intangible assets--$
1,000,000Issuance of 100,000 common shares to acquire furniture and fixtures--$
49,000Issuance of 78,000 common shares in satisfaction of accrued expenses--$
15,000Issuance of 10,500 shares to acquire furniture and fixtures--$
40,000Issuance of 1,400,00 of common shares to acquire Teneo Computing--$
785,000Issuance of 1,000,000 of common shares to purchase 42% of Novint Technologies--$
561,000Issuance of 641,274 shares of common stock in settlement of note payable--$
48,000Issuance of 3,180,552 common shares in satisfaction of accrued expenses--$
159,000Issuance of 1,277,685 common shares in satisfaction of accrued expenses--$
83,000Issuance of 795,324 of common shares in settlement of note payable--$
45,000Issuance of 1,184,220 common shares in satisfaction of accrued expenses--$
59,000Issuance of 106,000,000 common shares for conversion of convertible notes$ 1,060,000$
1,060,000Issuance of 14,200,106 common shares in satisfaction of related party
note payable$  71,000$
71,000Issuance of 15,000,000 common shares for acquisition of Metallicum, Inc.$       300,000$
300,000Issuance of 1,125,926 common shares in satisfaction of accrued expenses$         45,000$
45,000

F-16

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

NOTE 1 - ORGANIZATION AND OPERATIONS

Manhattan Scientifics, Inc., a Delaware corporation (formerly Grand Enterprises, Inc) (Grand) was established on July 31, 1992 and has three wholly-owned subsidiaries: Metallicum, Inc., (Metallicum), Tamarack Storage Devices, Inc. (Tamarack) and Teneo Computing, Inc. (Teneo) (collectively the Company), a development stage enterprise.  Currently, Metallicum is the only operating subsidiary; and Tamarack and Teneo are dormant.  On June 12, 2008, the Company acquired Metallicum, Inc, for 15,000,000 shares of Companys common stock, (See Note 11).

Manhattan Scientifics, Inc., operates as a technology incubator that seeks to acquire, develop and commercialize life-enhancing technologies in various fields, with emphasis in the areas of alternative energy, and consumer and commercial electronics. In this capacity, the Company continues to identify emerging technologies through strategic alliances with scientific laboratories, educational institutions, and scientists and leaders in industry and government.  The Company has a long standing relationship with Los Alamos Laboratories in New Mexico. During 2008, the Company refocused its efforts from the development of its fuel cell technologies to  its current focus on the development of nano-materials through the acquisition of Metallicum.

Metallicum is a nanotechnology start-up company located in Santa Fe, New Mexico. Metallicum Inc. has focused on the development and manufacture of nanostructured metals for medical implants and other applications.  Metallicum intends to establish manufacturing partner relationships with major Fortune 500 metals companies and strategic partnering with significant customers in the medical device & prosthetics industries as well as in auto, truck, & aircraft manufacturing industries. Metallicums initial products include noaostructured bulk metals and alloys in the form of rod, bar, wire and foil.  The Company conducts its operations primarily in the United States.

The Companys success will depend in part on its ability to obtain patents and product license rights, maintain trade secrets, and operate without infringing on the proprietary rights of others, both in the United States and other countries. There can be no assurance that patents issued to or licensed by the Company will not be challenged, invalidated, or circumvented, or that the rights granted thereunder will provide proprietary protection or competitive advantages to the Company.


NOTE 2  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Basis of Consolidation:

The consolidated financial statements include the accounts of Manhattan Scientific, Inc. and its wholly owned subsidiaries Tamarack, Teneo and Metallicum. All significant intercompany balances and transactions have been eliminated. The accompanying consolidated financial statements include the operating activities of Metallicum, Inc. from the June 12, 2008 (date of acquisition) through December 31, 2008.

The fiscal year end of the Company is December 31.

Development Stage Enterprise:

The Company has not generated any significant revenue since inception. The accompanying financial statements have, therefore, been prepared using the accounting formats prescribed by Financial Accounting Standards Board Statement No. 7, Accounting and Reporting by Development Stage Enterprises, (SFAS No. 7) for a development stage enterprise (DSE). Although the Company has recognized some nominal amount of revenue in the past, the Company still believes it is devoting substantial efforts on developing the business and, therefore, still qualifies as a DSE.




F-17

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

Going Concern Uncertainty:

For the years ended December 31, 2008 and 2007, the Company generated no revenues. The Company has incurred significant losses from operations from July 31, 1992, (inception) to December 31, 2008, and has an accumulated deficit of $52,643,000 and generated a net loss of $2,142,000. These factors raise substantial doubt about the Companys ability to continue as a going concern. The accompanying financial statements for the year ended December 31, 2008, have been prepared assuming the Company will continue as a going concern. Historically management obtained capital financing (debt or equity) to meet its working capital needs. During the year 2009, management intends to raise additional debt and/or equity financing to fund future operations and to provide additional working capital. However, there is no assurance that such financing will be consummated or obtained in sufficient amounts necessary to meet the Companys needs.

The accompanying financial statements do not include any adjustments to reflect the possible future effects on the recoverability and classification of assets or the amounts and classifications of liabilities that may result from the possible inability of the Company to continue as a going concern.

Use of Estimates:

The preparation of consolidated financial statements, in conformity with accounting principles generally accepted in the United States of America, requires management to make estimates and assumptions that affect the amounts in the financial statements and accompanying notes. Actual results could differ from those estimates.

Management makes estimates that affect, carrying value of the Companys patents, deferred income tax assets, estimated useful lives of property and equipment, useful lives of intangible assets,  accrued expenses, fair value of equity instruments and reserves for any other commitments or contingencies. Any adjustments applied to estimates are recognized in the year in which such adjustments are determined.

Cash and Cash Equivalents:

The Company considers all highly liquid investments purchased with an original maturity of three months or less at the time of purchase to be cash equivalents for the purposes of the statement of cash flows.

Cash Concentration:

The Company, at times, maintains cash balances in excess of the federally insured limit of $250,000 and $100,000 per institution in 2008 and 2007, respectively.  In December 2008, the Companys bank entered into the FDIC Temporary Liquidity Guarantee Program, which eliminated the ceiling on federally insured deposits.  The Companys cash balances are fully guaranteed by deposit insurance at December 31, 2008.

Property and Equipment:

Property and equipment are recorded at cost. Expenditures for major additions and improvements are capitalized, and minor replacements, maintenance, and repairs are charged to expense as incurred. When property and equipment are retired or otherwise disposed of, the cost and accumulated depreciation are removed from the accounts and any resulting gain or loss is included in the results of operations for the respective period. Depreciation is provided over the estimated useful lives of the related assets using the straight-line method for financial statement purposes. The Company uses other depreciation methods (generally accelerated) for tax purposes where appropriate. The estimated useful life for office equipment is generally 3 years.

As of December 31, 2008, the office equipment was fully depreciated
.


F-18

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

Impairment of Long-Lived Assets:

The Company assesses the impairment of its long-lived assets periodically in accordance with the provisions of Statement of Financial Accounting Standards ("SFAS") 144, "Accounting for the Impairment and Disposal of Long-Lived Assets". Whenever events or changes in circumstances indicate that the carrying amounts of long-lived assets may not be recoverable, the Company will compare undiscounted net cash flows estimated to be generated by those assets to the carrying amount of those assets. When these undiscounted cash flows are less than the carrying amounts of the assets, the Company will record impairment losses to write the asset down to fair value, measured by the discounted estimated net future cash flows expected to be generated from the assets. To date there has been no impairment.

Intangible Assets:

Patents

Intangible assets consist of patent licensing costs incurred to date. Patents consist of mid-range fuel cell and the micro fuel cell technologies that are being amortized using the straight-line method over the estimated economic useful life of 10 years. The Company has capitalized $2,080,000 in patent licensing costs as of December 31, 2008. Amortization charged to research and development expense was $194,000 and $208,000 for the years ended December 31, 2008 and 2007, respectively. At December 31, 2008 these patents were fully amortized.

License Agreements

In 2008,  the Company obtained licenses to the rights of certain patents regarding nano-structured materials developed by another company as a result of the acquisition of Metallicum. The purchase price paid for these licenses was $305,000, which represents its fair value.  The Company obtained an exclusive license on two patents and a non-exclusive license on the third patent. The value attributable to license agreements is being amortized over the period of its estimated benefit period of 10 years. At December 31, 2008, accumulated amortization was $15,000. Under the terms of the agreement, the Company may be required to pay royalties, as defined, to the licensors.

Investments

Available-for-Sale Investments


Investments that the Company designates as available-for-sale are reported at fair value, with unrealized gains and losses, net of tax, recorded in accumulated other comprehensive income (loss). The Company determines the cost of the investment sold based on the specific identification method. The Companys available-for-sale investments include:
Marketable equity securitiesThe Company acquires these equity investments for the promotion of business and strategic objectives. The Company records  the realized gains or losses on the sale or exchange of marketable equity securities in gains (losses) on other equity investments, net.
Non-Marketable and Other Equity Investments

The Company accounts  for non-marketable and other equity investments under either the cost or equity method and include them in other long-term assets. The non-marketable and other equity investments include:
Non-marketable cost method investmentswhen the equity method does not apply. We record the realized gains or losses on the sale of non-marketable cost method investments in gains (losses) on other equity investments, net.

Reclassifications

Certain amounts from prior periods have been reclassified to conform to the current period presentation. This reclassification has resulted in no changes to the Company's accumulated deficit or net losses presented.







Advertising Expenses:

The Company expenses advertising costs, which consist primarily of promotional items and print media, as incurred. During the year ended December 31, 2008 and 2007, the Company did not incur any significant advertising costs.

Income Taxes:

The Company accounts for its income taxes using the Financial Accounting Standards Board Statements of Financial Accounting Standards No. 109, Accounting for Income Taxes, which requires the establishment of a deferred tax asset or liability for the recognition of future deductible or taxable amounts and operating loss and tax credit carryforwards. Deferred tax expense or benefit is recognized as a result of timing differences between the recognition of assets and liabilities for book and tax purposes during the year.

Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. Deferred tax assets are recognized for deductible temporary differences and operating loss, and tax credit carryforwards. A valuation allowance is established, when necessary, to reduce that deferred tax asset if it is more likely than not that the related tax benefits will not be realized.

In June 2006, the Financial Accounting Standards Board issued FASB Interpretation No. 48 (FIN-48), Accounting for Uncertainty in Income TaxesAn interpretation of FASB Statement No. 109. FIN-48 clarifies the accounting for uncertainty in income taxes recognized in an entitys financial statements in accordance with Statement of Financial Accounting Standards No.109, Accounting for Income Taxes. This Interpretation prescribed a recognition threshold and measurement attribute for the financial statement recognition and measurement of a tax position taken or expected to be taken in a tax return. In addition, FIN-48 provides guidance on derecognition, classification, interest and penalties, accounting in interim periods, disclosure, and transition. The Company adopted the provisions of FIN-48 and they had no impact on its financial position, results of operations, and cash flows.

Based on its evaluation, the Company has concluded that there are no significant uncertain tax positions requiring recognition in its financial statements.  The Companys evaluation was performed for the tax years ended December 31, 2004 through December 31, 2008 for U.S. Federal Income Tax, for the tax years ended December 31, 2004 through December 31, 2008 for the States of New Mexico and New York Income Tax, the years which remain subject to examination by major tax jurisdictions as of December 31, 2008.


F-19

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

Convertible Notes Payable:

During 2007, the Company had issued convertible debt securities with non-detachable conversion features. The values assigned to the warrants and embedded conversion feature of the Debentures followed the guidance of the EITF Issue No. 98-5, Accounting for Convertible Securities with Beneficial Conversion Features or Contingently Adjustable Conversion Ratios, EITF 00-19: Accounting for Derivative Financial Instruments Indexed to, and Potentially Settled in, a Companys Own Stock, FAS No. 150, Accounting for Certain Financial Instruments with Characteristics of both Liabilities and Equity and EITF Issue No. 00-27, Application of Issue No. 98-5 to Certain Convertible Instruments of the FASBs Emerging Issues Task Force. The debt discount associated with the Warrants and embedded conversion feature is amortized to interest expense over the life of the Debenture or upon earlier conversion of the Debenture using the
effective yield method.

Stock-Based Compensation:

On January 1, 2006, the Company adopted SFAS 123 (revised 2004), Share-Based Payment (SFAS 123(R)), which requires the measurement and recognition of compensation expense for all share-based awards made to employees and directors, including employee stock options and shares issued through its employee stock purchase plan, based on estimated fair values. In March 2005, the Securities and Exchange Commission issued Staff Accounting Bulletins No. 107 and 110 (SAB 107 and SAB 110) relating to SFAS 123(R). The Company has applied the provisions of SAB 107 and SAB 110 in its adoption of SFAS 123(R). The Company adopted SFAS 123(R) using the modified prospective transition method, which requires the application of the accounting standard as of the beginning in 2006. The Companys financial statements as of and for the year ended December 31, 2008 and 2007 reflect the impact of SFAS 123(R). In accordance with the modified
prospective transition method, The Companys financial statements for prior periods include the impact of SFAS 123(R).

The estimated fair value of grants of stock options and warrants to nonemployees of the Company is charged to expense, if applicable, in the financial statements. These options vest in the same manner as the employee options granted under each of the option plans as described in Note 9. As of December 31, 2008 and 2007, the Company recorded compensation/service expense of $1,034,000 and $197,000, respectively.

Fair Value of Financial Instruments:

Effective January 1, 2008, the Company adopted SFAS No. 157, which provides a framework for measuring fair value under GAAP. The adoption of this statement had an immaterial impact on our consolidated financial statements. The Company also adopted the deferral provisions of FSP No. 157-2, which delays the effective date of SFAS No. 157 for all nonrecurring fair value measurements of non-financial assets and liabilities until fiscal years beginning after November 15, 2008.

Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. SFAS No. 157 also expands disclosures about instruments measured at fair value and establishes a fair value hierarchy which requires an entity to maximize the use of observable inputs and minimize the use of unobservable inputs when measuring fair value. The standard describes three levels of inputs that may be used to measure fair value:

Level 1  Quoted prices for identical assets and liabilities in active markets;

Level 2  Quoted prices for similar assets and liabilities in active markets; quoted prices for identical or similar assets and liabilities in markets that are not active; and model-derived valuations in which all significant inputs and significant value drivers are observable in active markets; and

Level 3  Valuations derived from valuation techniques in which one or more significant inputs or significant value drivers are unobservable.

The Company designates cash equivalents (consisting of money market funds) and investments in securities of publicly traded companies  as Level 1. The total amount of the Companys investment classified as Level 3 is de minimis.

The fair value of the Companys debt as of December 31, 2008 and  2007 approximated fair value at those times.

In January 2009, the Company adopted SFAS No. 159, The Fair Value Option for Financial Assets and Financial Liabilities, including an amendment of FASB Statement No. 115. SFAS No. 159 permits the Company to elect fair value as the initial and subsequent measurement attribute for certain financial assets and liabilities that are not otherwise required to be measured at fair value on an instrument-by-instrument basis. If the Company elects the fair value option, it would be required to recognize subsequent changes in fair value in the Companys earnings. This standard also establishes presentation and disclosure requirements designed to improve comparisons between entities that choose different measurement attributes for similar types of assets and liabilities. While SFAS No. 159 became effective for the Company in 2009, the Company did not elect the fair value measurement option for any of its existing assets and liabilities and
accordingly SFAS No. 159 did not have any impact on the Companys consolidated financial statements. The Company could elect this option for new or substantially modified assets and liabilities in the future.

Fair value of financial instruments: The carrying amounts of financial instruments, including cash and cash equivalents, short-term investments,  accounts payable, accrued expenses and notes payables approximated fair value as of  December 31, 2008 and  2007 because of the relative short term nature of these instruments. At December 31, 2008 and  2007, the fair value of the Company's debt approximates carrying value.

Revenue Recognition:

To date the only revenue generated is from the sale of non-exclusive license agreements related to the Companys  technology.  The Company has determined that because of the non-recurring nature of these revenues, it is still a Development Stage Enterprise.

Revenue is recognized when the four basic criteria of revenue recognition are met: (i) a contractual agreement exists; (ii) transfer of technology (intellectual property) has been completed or services have been rendered; (iii) the fee is fixed or determinable, and (iv) collectability is reasonably assured.

In January 2004, the Company licensed its mid-range fuel cell technology to a Singapore based company with manufacturing operations in China as part of its efforts to provide low cost fuel cell systems to Asian and other worldwide markets. Among other things, the contract gave the licensee non-exclusive rights to produce and sell fuel cell engines based on the NovArs technology. The agreement included an up-front payment of $150,000, royalties and 17.5% equity interest in the Singapore Company.  In December 2005, the Company sold its equity interest in the licensee back to the licensee for $885,000 which was recorded as other income.

In April 2003, the Company entered into a nonexclusive license agreement with a third party for rights to its mid-range fuel cell technology. The Company received $300,000 upon signing of the agreement and is entitled to receive an additional $200,000 upon commercial launch (as defined) by the third party.   To date, the licensee has not commenced its commercial launch.



F-20

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

Research and Development:

Research and development expenses include internal and external costs. Internal costs shall consist of salaries and employment related expenses and allocated facility costs. External expenses shall consist of costs associated with outsourced clinical research organization activities, sponsored research studies, product registration, and investigator sponsored trials. In accordance with SFAS No. 2, "Accounting for Research Development Costs", all such costs are charged to expense as incurred. During the years ended December 31, 2008 and 2007 the Company expensed research and development cost of $198,000 and $208,000, respectively. From inception the Company has incurred $9,020,000 in research and development expenses the balance which are related to its fuel cell, haptics and solar photovoltaic technologies.

Basic and Diluted Loss Per Share:

In accordance with SFAS No. 128, "Earnings Per Share," the basic loss per share is computed by dividing the loss attributable to common stockholders by the weighted average number of common shares outstanding during the period. Basic net loss per share excludes the dilutive effect of stock options or warrants and convertible notes Diluted net earnings (loss) per common share is determined using the weighted-average number of common shares outstanding during the period, adjusted for the dilutive effect of common stock equivalents, consisting of shares that might be issued upon exercise of common stock options and warrants. In periods where losses are reported, the weighted-average number of common shares outstanding excludes common stock equivalents, because their inclusion would be anti-dilutive.

The Companys computation of dilutive net loss per share for the year ended December 31, 2008 and 2007 does not assume any exercise of options, warrants or shares issuable upon conversion of the series B preferred stock and common shares, which totaled 40,245,000, 4,000,000 and 499,990 respectively, for the year ended December 31, 2008 and 38,245,000, 13,250,000 and 499,990 respectively for the year ended December 31, 2007, as their effect is antidilutive.

The following table sets forth the computation of basic and diluted net loss per common share:

Year Ended December 31,20082007Net income (loss)  available to common shareholders$(2,142,000)$(3,014,000)Weighted average common shares outstanding: Basic and diluted328,469,378249,567,399Total shares outstanding at end of period378,977,926318,545,000Net income (loss) per common share: Basic and diluted$(0.01)$(0.01)

The potential shares, which are excluded from the determination of basic and diluted net loss per share as their effect is anti-dilutive, are as follows:

20082007Series B Preferred Stock499,990499,990Options and Warrants44,245,00051,495,000Convertible debt600,000825,000Potential equivalent shares excluded45,344,99052,819,990


F-21

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

Recent Accounting Pronouncements:

In December 2007, the FASB issued SFAS No. 141 (Revised 2007), Business Combinations - Revised 2007. SFAS 141 (R) provides guidance on improving the relevance, representational faithfulness, and comparability of information that a reporting entity provides in its financial reports about a business combination and its effects. SFAS 141R applies to business combinations where is the acquisition date is on or after the beginning of the first annual reporting period beginning on or after December 15, 2008. The Company does not expect the adoption of SFAS No. 141 to have a material impact on its consolidated financial statements.

In December 2007, the FASB issued SFAS No. 160, Noncontrolling Interests in Consolidated Financial Statements - an Amendment of Accounting Research Bulletin No. 51 (SFAS No. 160), which establishes accounting and reporting standards for ownership interests in subsidiaries held by parties other than the parent, the amount of consolidated net income attributable to the parent and to the noncontrolling interest, changes in a parents ownership interest and the valuation of retained noncontrolling equity investments when a subsidiary is deconsolidated. SFAS No. 160 also establishes reporting requirements that provide sufficient disclosures that clearly identify and distinguish between the interests of the parent and the interests of the non-controlling owners. SFAS No. 160 is effective for fiscal years, and interim periods within those fiscal years, beginning on or after December 15, 2008.  The Company is currently evaluating the effect
of this pronouncement on its consolidated financial statements.

In March 2008, the FASB issued SFAS No. 161, Disclosures about Derivative Instruments and Hedging Activities  an amendment of FASB Statement No. 133, (SFAS 161) as amended and interpreted, which requires enhanced disclosures about an entitys derivative and hedging activities and thereby improves the transparency of financial reporting.  Disclosing the fair values of derivative instruments and their gains and losses in a tabular format provides a more complete picture of the location in an entitys financial statements of both the derivative positions existing at period end and the effect of using derivatives during the reporting period.  Entities are required to provide enhanced disclosures about (a) how and why an entity uses derivative instruments, (b) how derivative instruments and related hedged items are accounted for under Statement 133 and its related interpretations, and (c) how derivative instruments and
related hedged items affect an entitys financial position, financial performance, and cash flows.  SFAS No. 161 is effective for financial statements issued for fiscal years and interim periods beginning after November 15, 2008.  Early adoption is permitted.  At December 31, 2008, the Company did not have any derivative instruments or hedging activities. Management is aware of the requirements of SFAS 161 and will disclose when appropriate.

In May 2008, the FASB issued SFAS No. 162, The Hierarchy of Generally Accepted Accounting Principles.  SFAS 162 will provide framework for selecting accounting principles to be used in preparing financial statements that are presented in conformity with U.S. generally accepted accounting principles (GAAP) for nongovernmental entities.  SFAS 162 will be effective 60 days following the Securities and Exchange Commissions approval of the Public Company Accounting Oversight Board (PCAOB) amendments to AU Section 411.  The Company does not expect the adoption of SFAS 162 will have a material impact on its financial condition or results of operation.

In May 2008, the FASB issued SFAS No. 163, Accounting for Financial Guarantee Insurance Contracts  an interpretation of FASB Statement No. 60.  SFAS 163 requires that an insurance enterprise recognize a claim liability prior to an event of default (insured event) when there is evidence that credit deterioration has occurred in an insured financial obligation.  This Statement also clarifies how Statement 60 applies to financial guarantee insurance contracts, including the recognition and measurement to be used to account for premium revenue and claim liabilities. Those clarifications will increase comparability in financial reporting of financial guarantee insurance contracts by insurance enterprises. This Statement requires expanded disclosures about financial guarantee insurance contracts. The accounting and disclosure requirements of the Statement will improve the quality of information provided to users of financial statements.  SFAS 163





 will be effective for financial statements issued for fiscal years beginning after December 15, 2008.  The Company does not expect the adoption of SFAS 163 will have a material impact on its financial condition or results of operation.

In November 2008, the FASB ratified the Emerging Issues Task Force (EITF) consensus on Issue No. 08-6, Equity Method Investment Accounting Considerations (EITF 08-6) which addresses certain effects of SFAS Nos. 141R and 160 on an entitys accounting for equity-method investments. The consensus indicates, among other things, that transaction costs for an investment should be included in the cost of the equity-method investment (and not expensed) and shares subsequently issued by the equity-method investee that reduce the investors ownership percentage should be accounted for as if the investor had sold a proportionate share of its investment, with gains or losses recorded through earnings. EITF 08-6 is effective of us for transactions occurring after December 31, 2008.. Company has not determined the impact that this standard would have on the consolidated financial statements.

In November 2008, the FASB ratified the EITF consensus on Issue No. 08-7, Accounting for Defensive Intangible Assets (EITF 08-7). The consensus addresses the accounting for an intangible asset acquired in a business combination or asset acquisition that an entity does not intend to use or intends to hold to prevent others from obtaining access (a defensive intangible asset). Under EITF 08-7, a defensive intangible asset would need to be accounted as a separate unit of accounting and would be assigned a useful life based on the period over which the asset diminishes in value. EITF 08-6 is effective for us for transactions occurring after December 31, 2008. The Company has not determined the impact that this standard would have on the consolidated financial statements.

In January 2009, the FASB issued FSP No. EITF 99-20-1, Amendments to the Impairment Guidance of EITF Issue No. 99-20 (FSP No. EITF 99-20-1). This FSP provided additional guidance with respect to how entities determine whether an other-than-temporary impairment (OTTI) exists for certain beneficial interests in a securitized transaction, such as asset-backed securities and mortgage-backed securities, that (1) do not have a high quality rating or (2) can be contractually prepaid or otherwise settled such that the holder would not recover substantially all of its investment. FSP No. EITF 99-20-1 amended EITF Issue No. 99-20 to more closely align its OTTI guidance with that of SFAS No. 115, Accounting for Certain Investment in Debt and Equity Securities. This FSP was effective for us prospectively beginning October 1, 2008. The Company considered this FSPs additional interpretation of
EITF Issue No. 99-20 when classifying respective additional impairments as temporary or other-than-temporary beginning with the fourth quarter of 2008. This FSP had no material impact on such classifications.

NOTE 3  INVESTMENTS

At December 31, 2007, the Company owns less than 4% of Novint. The following is a summary of financial data regarding the financial position and results of operations derived from the December 31, 2007 financial statements of Novint as of December 31, 2007.

Current assets (including cash of $255,000)$3,987,000Property and equipment444,000Other assets1,218,000$5,649,000Liabilities$732,000Equity4,917,000$5,649,000Revenue$415,000Net/ Loss$(8,096,000)
The Company made an investment in Novint Technologies Inc. (Novint) in 2001. The Company initially recorded its investment using the equity method of accounting and wrote down the investment to $-0- in 2004 as it recorded its proportionate share of Novint's net loss.  For the years ended December 31, 2008 and 2007, the Company gave 53,191 and 92,216 shares of Novint stock as payment of accrued liabilities and notes payable, related party and recorded a gain on the exchange of those shares of $50,000 and $77,000, respectively which was based on the fair market value of the stock on the date of exchange.  In addition during the year ended December 31, 2007, the Company distributed 530,000 shares of Novint related to convertible promissory notes issued during 2007, as further discussed in Note 7.  As a result, the Company recognized a gain on this distribution totaling $393,000 during the year ended December 31, 2007.



In prior years, the Company had significant control of Novint because of Mr. Maslow's position as a shareholder and board member of both the Company and Novint.
Mr. Maslow resigned from the board of the Company in October 2007 and therefore the Company no longer has significant control of Novint.
As of December 31, 2008,  the Company  owned  1,075,648  shares of Novint common
stock or approximately 3% and modified its accounting for the ownership position
in accordance with SFAS 157. The fair value of the Novint shares are $129,000 as of December 31, 2008.

The Company has an additional investment in Aprilis, Inc. which is accounted for at a cost of $2,000.

NOTE 4OTHER ASSETS

Other assets consist of Artwork held for sale and deposits. The original cost of the artwork was $36,000.  During the year ended December 31, 2007 the Company impaired the value of the artwork to $28,000.

NOTE 5  RELATED PARTY AND FORMER OFFICER NOTES PAYABLE

In December 2007, the former Chief Operating Officer and former Chief Executive Officer collectively forgave $1,416,500 of their outstanding accrued salaries ($1,387,500) and note payable ($29,000) balances.  The amount forgiven has been accounted for as contributed capital.  Additionally, the Company repaid $5,000 of the former Chief Executive Officers note payable balance.  The remaining unpaid notes payable balances totaling $995,000 at December 31, 2008 and 2007 comprised of loans payable of $450,000 and $545,000 to its former Chief Operating Officer and Chief Executive Officer, respectively.

The loans bore interest at 5.5% per annum and were initially due December 31, 2002 and have been mutually extended and settled.  Under the terms of the note extensions dated December 12, 2007, the loans bear interest at 5% per annum and are now due on demand.  The Company has recorded interest expense for notes payable to these former officers of approximately $50,000 and $61,000 for the years ended December 31, 2008 and 2007, respectively.  Accrued interest related to these notes payable approximated $281,750 and $232,000 as of December 31, 2008 and 2007, respectively and is included in accrued liabilities, related parties.

In May 2007, the Company issued 14,200,106 shares of common stock to its former Chief Executive Officer for settlement of debt totaling $71,000.




F-22

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

NOTE 6  CONVERTIBLE NOTES PAYABLE  OTHER

During the years ended December 31, 2005 and December 31, 2004, the Company issued convertible notes in the amount of $33,000. The notes had a one year maturity date, are noninterest bearing and upon maturity convertible at the current per share price. These notes have not been paid and are currently in default.

.
NOTE 7  CONVERTIBLE PROMISSORY NOTES

During 2007, the Company issued a number of convertible promissory notes totaling $1,060,000 through a private placement.  The notes had a maturity date of December 2007, were noninterest bearing and convertible into shares of the Companys common stock at a conversion price of $0.01 per share,convertible upon shareholder approval to amend our Certificate of Incorporation to increase the authorized common stock from 250,000,000 shares to 500,000,000 shares.  For every $1 of principal debt held, the convertible debt holder was also entitled to half of a share of stock in Novint Technologies, Inc, held by the Company, for a total of 530,000 Novint shares.

In October 2007, upon shareholder approval of the amendment to the Certificate of Incorporation, the Company issued 106,000,000 shares of its common stock on the conversion of all the notes.  The Company determined the convertible notes contained a beneficial conversion feature and qualified for treatment under Emerging Issues Task Force No. 00-27 and 00-19.

The estimated fair value of the 530,000 shares of common stock in Novint Technologies, Inc. of $625,725 was determined based on the closing stock price of such stock on the date of each respective note.  The face amount of the convertible debenture of $1,060,000 was proportionately allocated to the debenture and the shares of common stock in Novint Technologies, Inc. in the amount of $667,000 and $393,000, respectively. The value of the Novint stock was accounted for as a debt discount and was amortized to expense over the term of the note.

At the conversion date, the Company had amortized $301,000 of this discount.  The remaining discounted value of $968,000 was allocated to the beneficial conversion feature. The combined total value of the Novint stock and beneficial conversion feature of $1,361,000 has been accounted for as a debt discount and has been fully expensed as a finance charge within General and Administrative Expense on the accompanying consolidated statement of operations for the year ended December 31, 2007.



F-23

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

NOTE 8  STOCKHOLDERS EQUITY

Preferred Stock

The Company has a total of 1,000,000 shares of authorized preferred shares which are segregated into three classes of preferred stock.

The Company has 182,525 authorized shares of convertible, redeemable, 10 percent cumulative, Class A, Preferred Stock with $0.001 par value. One Class A, Preferred share is convertible into 50 restricted common share and will be entitled to the number of votes equal to the number of shares of common stock into which such holders shares of Series A Preferred stock could be converted at the time of the vote. Class A, Preferred Stock is redeemable by the Company at $15 per share.  Upon liquidation the holders of Series A Preferred stock will be entitled to be paid out of the assets available for distribution of the corporation an amount equal to $10 per share, before any payment will be made to the common shareholders.  As of December 31, 2008 and 2007, no shares of Preferred Stock were issued and outstanding.

The Company has 250,000 authorized shares of Class B, Preferred Stock with $0.001 par value.  As of December 31, 2008 and 2007, 49,999 shares of Preferred Stock were issued and outstanding.  Series B preferred shares are convertible at a rate of 1 Series B preferred share to 10 common shares.

The Company has 14,000 authorized shares of redeemable, convertible, Class C, Preferred Stock with $100 stated value.  Class C, Preferred Stock is not entitled to receive dividends unless dividends are paid on common stock.  Upon liquidation Class C, Preferred Stock shall be treated as if it were converted to common stock prior to liquidation. Class C, Preferred Stock is convertible at $100 divided by the 10 day average closing price of common stock.  The Class C, Preferred Stock is redeemable by the Company at the stated value. As of December 31, 2008 and 2007, no shares of Preferred Stock were issued and outstanding.

The Company has 553,475 undesignated blank check preferred stock, $0.001 par value, authorized, none outstanding.  The preferred shares are to be issued in such series and to have such rights, preferences, and designation as determine by the Board of Directors of the Company.

Common Stock

The Company has a total of 500,000,000 shares of authorized common shares.  As of December 31, 2008 and 2007, 378,997,926 and 318,545,000 shares of common stock were issued and outstanding, respectively.

Stock issued during 2008

During the year ended December 31, 2008, the Company issued 1,125,926 shares of common stock for past services for a total value of $45,000

In January 2008, the Company granted options for 18,000,000 shares of common stock with an exercise price of $0.013 to the Companys former CEO and a consultant.  These options were fully vested at issuance and replaced 16,000,000 options previously granted with an exercise price of $0.05 per share.  The value of these options approximated $1,034,000 which was valued using the Black-Scholes option pricing model.

During the year ended December 31, 2008, the Company issued 1,600,000 shares of common stock for services for a total value of $57,000.



F-24

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

During April 2008 through  December 2008, the Company sold 42,707,000  shares of
common  stock  for   approximately   $850,000   from a   private  placement
offering.  The private placement originally provided for the offer and
sale of up to 50,000,000  unregistered shares of the Companys common stock
at a price of $0.02 per share,  for an aggregate  offering  price of $1,000,000,
and  allowed the  Company to  accept or reject  any  oversubscription.
  The  Company incurred offering costs totaling  approximately $46,000
of which $27,000 paid in cash and 750,000 common shares were issued.

In June 2008, the Company issued 15,000,000 shares of common stock for the acquisition of Metallicum, Inc. for a total value of $300,000 or $0.02 per share. See Note 14.


Stock issued during 2007

In March 2007, the Company granted an option for 10,000,000 shares of common stock with an exercise price of $0.014 to the Companys former CEO and chairman for services previously provided. The value of this option totaled $109,982 which was valued using the Black-Scholes option pricing model based upon the following assumptions: stock price of $0.014 at grant date; 5 year term; volatility of 107%; and discount rate of 4.50%.

In May 2007, the Company issued 35,350,317 shares of common stock to various individuals for services with values totaling $707,006 based upon the fair value of the shares issued, and 14,200,106 shares of common stock to its former Chief Executive Officer for settlement of debts totaling $71,000.

In October 2007, the Company issued 4,200,000 shares of common stock for services to an individual with a value of $60,900 based upon the fair value of the shares issued.

In October 2007, the Company issued 106,000,000 shares of common stock related to the conversion of convertible debt previously issued during 2007.  The convertible debt converted totaled $1,060,000 at which time the entire debt discount of $1,361,000 had been expensed.  See Note 7.

In October 2007, the Company granted warrants for 3,200,000 shares of common stock with an exercise price of $0.013 to various individuals for past services.  The value of these warrants totaled $36,444 which were valued using the Black-Scholes option pricing model based upon the following assumptions: stock price of $0.013 at grant date; 5 year term; volatility of 135%; and discount rate of 4.50%.

In November 2007, the Company issued 1,000,000 shares of common stock to an individual for services with a value of $30,000 based upon the fair value of the shares issued.

In November 2007, the Company issued 1,000,000 shares of common stock to an individual for services to be provided with a value of $30,000 based upon the fair value of the shares issued.

In November 2007, the Company granted an officer a warrant for 800,000 shares of common stock with an exercise price of $0.013.  The value of this warrant totaled $49,768 which was valued using the Black-Scholes option pricing model based upon the following assumptions: stock price of $0.065 at grant date; 5 year term; volatility of 142%; and discount rate of 4.50%.

As part of the settlement in December 2007, the former Chief Operating Officer and former Chief Executive Officer collectively forgave $1,416,500 of their outstanding accrued salaries ($1,387,500) and note payable ($29,000) balances.  The amount forgiven has been accounted for as contributed capital. See Note 5.



F-25

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

NOTE 9  EQUITY COMPENSATION PLANS

In 2000, the Companys Board of Directors adopted the 2000 Equity Incentive Plan (the "2000 Plan"). The 2000 Plan authorizes the issuance of options, right to purchase Common Stock and stock bonuses to officers, employees, directors and consultants. The Company reserved 30,000,000 shares of common Stock for awards to be made under the 2000 Plan.

On September 14, 2001, the Company filed a registration statement on Form S-8 to register 900,000 of these shares. On November 19, 2001, an additional 550,000 shares of common stock were registered for issuance under the 2000 Plan. On January 30, 2002, an additional 975,000 shares of common stock were registered for issuance under the 2000 Plan. On March 22, 2002, an additional 925,000 shares of common stock were registered for issuance under the 2000 Plan. On July 12, 2002, an additional 990,000 shares of common stock were registered for issuance under the 2000 Plan. On January 17, 2003, the Company registered an additional 8,000,000 of common stock for issuance under the 2000 Plan.

The 2000 Plan is administered by a committee of two or more members of the Board of Directors or, if no committee is appointed, then by the Board of Directors. The 2000 Plan allows for the issuance of incentive stock options (which, pursuant to Section 422 of the Internal Revenue Code, can only be granted to employees), non-qualified stock options, stock appreciation rights, stock awards, or stock bonuses. The committee, or the Board of Directors if there is no committee, determines the type of option granted, the exercise price, the option term, which may be no more than ten years, terms and conditions of exercisability and methods of exercise. Options must vest within ten-years. Under the 2000 Plan, the exercise price may not be less than fair market value on the date of grant for the incentive stock options. The 2000 Plan also allows for the granting of Stock Appreciation Rights. No Stock Appreciation Rights have been granted. The number of shares under the 2000 Plan
available for grant at December 31, 2008 was 25,281,000.

In November 2004, the Companys Board of Directors adopted the 2004 Consultant Stock Plan (the "2004 Plan"). The purpose of this 2004 Consultant Stock Plan is to advance the Companys interests by helping the Company obtain and retain the services of persons providing consulting services upon whose judgment, initiative, efforts and/or services we are substantially dependent, by offering to or providing those persons with incentives or inducements affording such persons an opportunity to become owners of our capital stock.

The Company reserved 2,000,000 shares of Common Stock for awards to be made under the 2004 Plan. A registration statement on Form S-8 was filed with the SEC on November 26, 2004 to register the shares underlying the 2004 plan. The 2004 Plan is administered by a committee of two or more members of the Board of Directors or, if no committee is appointed, then by the Board of Directors. The committee or the Board of Directors if there is no committee, determines who is eligible to receive awards under the plan, grant awards and interpret the 2004 Plan. The number of shares under the 2004 Plan available for grant at December 31, 2008 was 500,000.

On May 9, 2005, the Companys Board of Directors adopted the 2005 Equity Compensation Plan (the "2005 Plan"). The purpose of this Plan is to provide incentives to attract, retain and motivate eligible persons whose present and potential contributions are important to our success, by offering them an opportunity to participate in the Companys future performance through awards of Options, the right to purchase Common Stock and Stock Bonuses. The Company reserved 10,000,000 shares of Common Stock for awards to be made under the 2005 Plan. The 2005 Plan is administered by a committee of two or more members of the Board of Directors or, if no committee is appointed, then by the Board of Directors. The committee or the Board of Directors if there is no committee, determines who is eligible to receive awards under the plan, grant awards and interpret the 2005 Plan. A registration statement on Form S-8 was filed with the SEC on June 8, 2005 to register the
shares underlying the 2005 plan. The number of shares under the 2005 Plan available for grant at December 31, 2008 was 4,868,763.



F-26

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

Set forth in the table below is information regarding awards made through compensation plans or arrangements through December 31, 2008, the most recently completed fiscal year.

Equity Compensation Plan InformationPlan categoryNumber of securities to be issued upon exercise of outstanding options, warrants and rights
(a)Weighted-average exercise price of outstanding options, warrants and rightsNumber of securities remaining available for future issuance under equity compensation plans (excluding securities reflected in column (a)Equity compensation plans approved by security holders---Equity compensation plans not approved by security holders--30,649,763Total--30,649,763
The following is a summary of changes to outstanding stock options during the years as follows:

Number of OptionsExercise Price Per ShareWeighted Average Exercise PriceNumber of Options ExercisableOutstanding as of December 31, 200628,245,0000.0130.01328,245,000Granted/Vested10,000,0000.0140.01410,000,000Canceled--Outstanding as of December 31, 200738,245,0000.01138,245,000Granted18,000,0000.0130.01318,000,000Cancelled(16,000,000)0.0500.050(16,000,000)Outstanding as of December 31, 200840,245,0000.01140,245,000
All options issued during 2008 and 2007 vested immediately and have a life of ten years.



F-27

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

Exercise prices and weighted-average contractual lives of stock options outstanding as of December 31, 2008 are as follows:

Options OutstandingOptions ExercisableExercise PriceNumber OutstandingWeighted Average Remaining Contractual LifeWeighted Average Exercise PriceNumber ExercisableWeighted Average Exercise Price$0.0128,000,0008.680.01328,000,0000.010.021,800,0004.680.0201,800,0000.020.052,625,0001.650.0502,625,0000.050.051,000,0006.580.0551,000,0000.050.205,760,0000.710.2005,760,0000.200.39250,0003.980.390250,0000.391.25200,0003.981.250200,0001.252.25110,0002.462.250110,0002.252.40500,0002.332.400500,0002.40
As of December 31, 2008, the following assumptions were used: (i) no expected dividends; (ii) a risk-free interest rate of 4.5% (iii) expected volatility 144%, and (iv) 5 year term. The fair value was determined using the Black-Scholes option-pricing model.

As of December 31, 2007, the following assumptions were used: (i) no expected dividends; (ii) a risk-free interest rate of 4.5% (iii) expected volatility 107% and (iv) 5 year term. The fair value was determined using the Black-Scholes option-pricing model

NOTE 10  WARRANTS

The Company issued the following warrants at the corresponding weighted average exercise price as of December 31, 2008 and 2007.

Number of
WarrantsWeighted average
Exercise PriceOutstanding as of December 31, 200619,250,000$0.13Issued4,000,0000.01Cancelled(10,000,000)0.05Outstanding as of December 31, 200713,250,0000.15Issued-Expired(9,250,000)0.32Outstanding as of December 31, 20084,000,0000.03



F-28

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

The common stock warrants are comprised of the following:

DateNumber of WarrantsExercise PriceContractual LifeNumber of Shares ExercisableOctober 11, 20073,200,000.0110 years3,200,000November 9, 2007800,000.0110 years800,0004,000,0004,000,000The estimated fair value of the warrants was calculated using the Black-Scholes valuation model. For warrants issued in 2007 the following assumptions were used: (i) no expected dividends, (ii) risk free interest rate of 4.5%, (iii) expected volatility of 135 - 142%, (iv) 5 year term.  No warrants were issued during 2008.

NOTE 11  RELATED PARTY TRANSACTIONS

The accounting firm of one of the Companys former directors received approximately $48,000 and $35,000 of compensation for accounting services rendered to the Company during the years ended December 31, 2008 and 2007, respectively.

The  accounting  firm of one of the  Companys  former  directors  received
approximately  $9,000  and  $9,000  of  compensation  for  accounting  services
rendered to the Company during the year ended December 31, 2007.

Mr. Marvin Maslow is a shareholder and board member of Novint and a shareholder and previous member of the board of the Company.

NOTE 12  INCOME TAX

The provision for income taxes on the statements of operations consists of $-0- and $-0- for the years ended December 31, 2008 and 2007, respectively.

Deferred tax assets are comprised of the following at December 31:

2008
2007
Net operating loss carryforward
$ 8,696,800
$ 8,287,000
Temporary Differences
4,854,600
4,441,000
Less valuation allowance
(13,551,400)
(12,728,000)

Deferred taxes arise from temporary differences in the recognition of certain expenses for tax and financial reporting purposes.  At December 31, 2008 and 2007, management determined that realization of these benefits is not assured and has provided a valuation allowance for the entire amount of such benefits.  At December 31, 2008 and 2007, net operating loss carryforwards were approximately $34,663,000 and $31,834,000, respectively, for federal tax purposes that expire at various dates from 2009 through 2028 and for state tax purposes expire in 2009 through 2018.

Utilization of net operating loss carryforwards may be subject to substantial annual limitations due to the change in ownership provisions of the Internal Revenue Code of 1986, as amended, and similar state regulations.  The annual limitation may result in the expiration of substantial net operating loss carryforwards before utilization.

For December 31, 2008 and 2007, the provision for income taxes differs from the amount computed by applying the U.S. federal statutory tax rate (34% in 2008 and 2007) to income taxes as follows:

2008
2007
Tax benefit computed at 34%
$   414,800
$    629,600
Change in valuation allowance
(828,400)
(708,400)
Change in carryovers and tax attributes
413,600
78,800



F-29

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

NOTE 13 COMMITMENTS

Operating Leases
The Companys principal executive offices in New York are leased on a month to month basis for $500 per month.  As of December 31, 2008 and 2007, rent expense was $6,000, and $6,000 respectively.
Litigation

The Company is subject from time to time to litigation, claims and suits arising in the ordinary course of business.  As of December 31, 2008 and 2007, the Company was not party to any material litigation, claims or suit whose outcome could have material effect to the financial statements.

NOTE 14  ACQUISITION OF METALLICUM, INC.

In June 12, 2008, the Company completed the purchase of Metallicum, Inc., a privately held research and development company of nano-structured materials, by acquiring all of the outstanding capital stock of Metallicum, Inc. for a total purchase price of $305,000. Metallicum, Inc.s results of operations have been included in the consolidated financial statements since the date of acquisition. As a result of the acquisition, the Company is expected to be a leading provider of nano-structured materials and uses of these materials.

The aggregate purchase price of $305,000 consisted of common stock valued at $300,000 and the assumption of net liabilities of $5,000. The value of the 15 million common shares issued was determined based on the price of the Companys common shares sold in a private placement offering to various accredited investors in 2008. The number of shares sold in the private placement is a greater indicator of fair value of the common stock since the Companys stock is very thinly-traded on the NASDAQ OTCBB.

The following table presents the allocation of the acquisition cost to the assets acquired and liabilities assumed, based on their fair values:

Cash and cash equivalents$  7,000Other current assets1,000Intangible assets305,000Total assets acquired313,000Accounts payable and other current liabilities(13,000)Total liabilities assumed(13,000)Net assets acquired$ 300,000

The purchase price exceeded the fair values of the net assets acquired by $305,000, and this total amount was assigned to License Agreements, which are being amortized on the straight-line method over the estimated remaining lives of ten years.

The Company originally valued the acquisition at $562,500 based upon the fair market value of the shares issued at the date of acquisition. In accordance with EITF Issue No. 99-12, Determination of the Measurement Date for the Market Price of Acquirer Securities Issued in a Purchase Business Combination the Company revised its estimate to more closely reflect the market price of its private placement both before and after the acquisition. This change in estimate had no affect on the current years net loss.

In connection with the Metallicum acquisition, the Company has agreed to pay additional consideration in future periods, based upon the attainment by the acquired entity of defined operating objectives. In accordance with Statement of Financial Accounting Standards No. 141, Business Combinations, the Company does not accrue contingent consideration obligations prior to the attainment of the objectives. At December 31, 2008, maximum potential future consideration pursuant to such arrangements, to be resolved over the following years, is the  potential issuance of 15 million restricted shares of the Companys common stock having a current approximate value of $300,000. Any such payments would result in increases in intangible assets.

The required milestones for the issuance of these contingent shares are as follows:

1.
Metallicum is granted an exclusive license by The Los Alamos National Laboratory (LANL) on patent numbers U.S.7152448, U.S.6399215 and U.S. 6197129 related to nanostructured materials.
2.
Metallicum sells nanostructured titanium to a partner or customer company which manufactures and sells in the United States a nonostructured titanium product which receives, if required, FDA approval.
3.
Metallicum, with purchasers cooperation, develops and submits U.S. patent applications to protect the current titanium nanostructuring technology for dental implants and additional medical device applications
4.
Metallicum secures commercial contracts for, in purchasers reasonable good faith judgment, material sales of nanostructured metal with at least two customers.
5.
The nanostructured metals enterprise is functioning on June 30, 2010.

Upon achieving milestones 1 and 2 Metallicum will receive 6,000,000 shares of common stock. Upon achieving each milestone 3, 4 and 5 Metallicum shareholders will receive 3,000,000 shares of common stock for each milestone reached.

At December 31, 2008 none of the milestones have been met. In January 2009, the Company did reach milestone 1.

License Rights
The Company purchased Metallicum to acquire its licensed rights to patented technology.  The technology is comprised of three US Patents (US Patent numbers 7152448, 6197129 and 6399215) for which Metallicum (subsequently, Manhattan) had been assigned an exclusive license rights by Los Alamos National Security LLC (LANL).  Under the license rights, Metallicum had all rights, title and interest throughout the world in and to any and all inventions, original works of authorship, developments, concepts, know-how, improvements on the patents or trade secrets whether or not patentable or registrable under copyright or similar laws.

Joint Venture
Metallicum has a joint venture agreement with Danlin Products Inc, (Danlin) and BASIC Dental Inc., (BASIC),  Danlin and BASIC own patents to which Metallicum has right of use.  Danlin and BASIC own machinery and equipment to which Metallicum has rights of use under the joint venture agreement. Metallicum, through its joint venture has co-developed and manufactured nano-titanium dental implants based upon Metallicums proprietary technology for nanostructuring metals and alloys. In January 2009, Danlin and BASIC received FDA approval to market the Companys nano-titanium dental implants.

Metallicum will receive revenue from the transfer of nanostructured metal from Metallicum to Danlin equal to 10% of the revenue from the sales of BASIC dental implants that are made from the supplied nanostructured metal.
Revenue from sales of nanostructured titanium for all other purposes other than the implants will go to the joint venture to be paid to Metallicum.

Any techniques, know-how, improvements, or modification to the existing inventions, intellectual property and technologies that are developed by the joint venture will be the sole and exclusive property of Metallicum.

The following pro forma consolidated financial information are the results of operations for the years ended December 31, 2008 and 2007 as though the Metallicum acquisition had been completed as of the beginning of the period being reported on:


F-30

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007


For the year ended December 31, 2008Consolidated
As ReportedPro Forma AdjustmentsPro Forma ConsolidatedRevenue$-$2,000$2,000Operating costs and expenses:General and administrative1,952,0002,0001,954,000Research and development costs198,0003,000201,000Total operating costs and expenses2,150,0005,0002,155,000Loss from operations(2,150,000)(5,000)(2,155,000)Other income (expenses):8,000(1,000)7,000Net Loss$(2,142,000)$(6,000)$(2,148,000)Loss per share$0.01$0.00$0.01


F-31

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007


For the year ended December 31, 2007Consolidated
As ReportedPro Forma AdjustmentsPro Forma ConsolidatedRevenue$-$4,000$4,000Operating costs and expenses:General and administrative3,233,0006,0003,239,000Research and development costs210,0003,000213,000Total operating costs and expenses3,443,0009,0003,452,000Loss from operations(3,443,000)(5,000)(3,448,000)Other income (expenses):429,000(1,000)428,000Net income (loss)$(3,014,000)$(6,000)$(3,020,000)Loss per share$0.01$0.00$0.01
The pro forma adjustments for the years ended December 31, 2008 and 2007 are the revenue and expense activities from January 1, 2008 through June 11, 2008 and January 1, 2007 through December 31, 2007 (activities prior to consummation of the purchase agreement).


NOTE 15  SUBSEQUENT EVENTS

Exclusive Patent License Rights

In January 2009, the Company paid LANL to obtain the exclusive field-of-use patent license directly.  In addition, the Company is required to pay an annual royalty beginning February 28, 2010, for the patent license rights. The Company also issued 2,000,000 shares of common stock to Los Alamos National Security LLC.  Manhattan will pay LANL an earned royalty on the net sales of licensed inventions that incorporate the patent rights during the term of the license agreement.

The Company will have the right to sublicense these patents.  Sublicenses will contain a provision that will require payment of royalties by the sublicensees to the Company in an amount sufficient to allow the Company to meet its royalty obligation to LANL. The Company will pay to LANL a percentage from fees, royalties and reimbursement of costs of any cash or the cash equivalent of sublicense consideration that the Company receives for the grant of rights under each sublicense agreement.

The license rights also require the Company to meet certain milestones.  Twelve months from the effective date of the license rights agreement Manhattan will initiate negotiations with at least five companies regarding manufacture and distribution of licensed products.  Within twenty-four months Manhattan will establish capability for manufacturing a licensed product in New Mexico and within thirty-six months Manhattan will either manufacture a licensed product or close a sublicense agreement, or initiate a request for required government approval for a licensed product.



F-32

MANHATTAN SCIENTIFICS, INC.
(A Development Stage Enterprise)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Audited)
DECEMBER 31, 2008 AND 2007

Equity Issued

During January 2009, the Company sold an additional  8,950,000  shares of common
stock for  approximately  $179,000  from a  private  placement  offering  having
commenced in April 2008. The private placement originally provided for the offer
and sale of up to 50,000,000  unregistered  shares of the Companys  common
stock  at a price  of  $0.02  per  share,  for an  aggregate  offering  price of
$1,000,000,  and allowed  the Company to accept or reject any  oversubscription.
In  addition,  2,000,000  of the shares sold in this  placement  valued at
$40,000 were issued as payment of legal services and no cash was received by the
Company.  All of the shares sold in the private  placement  were issued in
February 2009.

In February 2009, the Company issued 1,000,000 shares to a consultant for services to be performed for a total value of $54,000 or $0.054 per share.

In February 2009, the Company issued 300,000 shares of common stock to a consultant for past services for a total value of $15,000 or $0.05 per share which had been included in accrued expenses at December 31, 2008.









F-33

ITEM 9. CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS

On March 27, 2009, we dismissed AJ. Robbins, PC as its independent registered public accounting firm.  On March 27, 2009, we engaged PMB Helin Donovan, LLP as our new independent registered public accounting firm. Our board of directors has approved the dismissal of AJ. Robbins, PC and the appointment of PMB Helin Donovan, LLP as our new independent registered public accounting firm.

During the fiscal years ended December 31, 2007 and 2006, and the subsequent interim periods through March 27, 2009, there were no disagreements between us and AJ. Robbins, PC on any matter listed under Item 304 Section (a)(1)(iv) of Regulation S-K, including accounting principles or practices, financial statement disclosure or auditing scope or procedure which, if not resolved to the satisfaction of AJ. Robbins, PC would have caused AJ. Robbins, PC to make reference to the matter in its reports on our financial statements.  For the fiscal years ended December 31, 2007 and 2006, the reports of AJ. Robbins, PC on our financial statements for those fiscal years then ended did not contain an adverse opinion or a disclaimer of opinion, nor were they qualified or modified as to uncertainty, audit scope or accounting principle, except that the reports of AJ. Robbins, PC included a qualification as to our ability to continue as a going concern.

During the fiscal years ended December 31, 2007 and 2006 and the subsequent periods through March 27, 2009, prior to engaging PMB Helin Donovan, LLP, we did not consult PMB Helin Donovan, LLP regarding either:

1.the application of accounting principles to any specified transaction, either completed or proposed, or the type of audit opinion that might be rendered on our financial statements, and neither a written report was provided to our company nor oral advice was provided that PMB Helin Donovan, LLP concluded was an important factor considered by us in reaching a decision as to the accounting, auditing or financial reporting issue; or
2.any matter that was either subject of disagreement or event, as defined in Item 304(a)(1)(iv) of Regulation S-K and the related instruction to Item 304 of Regulation S-K, or a reportable event, as that term is explained in Item 304(a)(1)(iv) of Regulation S-K.
During the fiscal years ended December 31, 2007 and 2006 and the subsequent periods through March 27, 2009, prior to engaging PMB Helin Donovan, LLP, PMB Helin Donovan, LLP has not provided our company with either written or oral advice that was an important factor considered by our company in reaching a decision to change our companys new independent registered public accounting firm from AJ. Robbins, PC to PMB Helin Donovan, LLP.

ITEM 9A. CONTROLS AND PROCEDURES

(a) Evaluation of Disclosure Controls and Procedures

Our principal executive and principal financial officers have evaluated the effectiveness of our disclosure controls and procedures, as defined in Rules 13a  15(e) and 15d  15(e) under the Securities Exchange Act of 1934, as amended (the Exchange Act), as of the end of the period covered by this annual report.  Our evaluation, which was not done using the COSO framework, immediately revealed that there were material weaknesses primarily as a result of our lack of personnel and management did not prepare a written report.  With only one full-time employee in general management, we realized that material weaknesses were unavoidable and hired outside professionals to assist us where possible.  Without third-party specialists, our current disclosure controls and procedures are not effective to provide reasonable assurance that material information required to be included in our periodic SEC reports is recorded, processed, summarized and
reported within the time periods specified in the SEC rules and forms, and accumulated and communicated to our senior management, including our CEO, to allow timely decisions regarding required disclosures.

Internal control over financial reporting as defined in Rules 13a-15(f) and 15d-15(f) refers to the process designed by, or under the supervision of, our principal executive officer and principal financial officer, and effected by our board of directors, management and other personnel, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles.

Internal control over financial reporting cannot provide absolute assurance of achieving financial reporting objectives because of its inherent limitations. Internal control over financial reporting is a process that involves human diligence and compliance and is subject to lapses in judgment and breakdowns resulting from human failures. Internal control over financial reporting also can be circumvented by collusion or improper management override. Because of such limitations, there is a risk that material misstatements may not be prevented or detected on a timely basis by internal control over financial reporting. However, it is possible to design into the process safeguards to reduce, though not eliminate, this risk.

Management is responsible for establishing and maintaining adequate internal controls over financial reporting.  Beginning in 2007, management outsourced its accounting function including the financial reporting aspects to a CPA firm.  Concerning these outsourced services, management did not receive a SAS 70 (type 1 nor type 2) audit report covering the internal controls over the services provided by the CPA firm.  Absent this report, and based upon managements knowledge of our operations and accounting functions, managements assessment concerning the effectiveness of our internal controls and disclosure controls and procedures is that those are not effective to provide reasonable assurance that material information required to be included in our periodic SEC reports is recorded, processed, summarized and reported within the time periods specified in the SEC rules and forms, and accumulated and communicated to our senior management, including our





 CEO, to allow timely decisions regarding required disclosures.

Our known material weaknesses include:

Resources: As of December 31, 2008, we had one full-time employee in general management and no full-time employees with the requisite expertise in the key functional areas of finance and accounting.  As a result, there is a lack of proper segregation of duties necessary to insure that all transactions are accounted for accurately and in a timely manner.

Written Policies & Procedures: We need to prepare written policies and procedures for accounting and financial reporting to establish a formal process to close our books monthly on an accrual basis and account for all transactions, including equity transactions, and prepare, review and submit SEC filings in a timely manner.

Audit Committee: We do not have, and are not required, to have an audit committee.  An audit committee would improve oversight in the establishment and monitoring of required internal controls and procedures.

Given the existence of these material weaknesses, management believes that other, non-identified material weaknesses may have existed and continue to exist.  These material weaknesses will be remedied as described below.

Management is committed to improving its internal controls and will (1) perform an assessment of its internal control using the COSO framework or other framework as deemed appropriate, (2) continue to use third party specialists to address shortfalls in staffing and to assist us with accounting and finance responsibilities, (3) increase the frequency of independent reconciliations of significant accounts which will mitigate the lack of segregation of duties until there are sufficient personnel and (4) prepare and implement sufficient written policies and checklists for financial reporting and closing processes and (5) may consider appointing an audit committee comprised of independent board members in the future.

This annual report does not include an attestation report by our registered public accounting firm regarding our internal controls over financial reporting.

(b) Changes in Internal Controls

There were no significant changes in our internal controls or, to our knowledge, in other factors that could significantly affect our internal controls subsequent to the evaluation date.

ITEM 9B. OTHER INFORMATION

None.

18

PART III
ITEM 10. DIRECTORS, EXECUTIVE OFFICERS, PROMOTERS AND CONTROL PERSONS; COMPLIANCE WITH SECTION 16(a) OF THE EXCHANGE ACT
The names, ages and biographical information of each of our directors and executive officers as of December 31, 2008 are set forth below. There are no existing family relationships between or among any of our executive officers or directors.

NAMEAGEPOSITIONEmmanuel Tsoupanarias56Chairman of the Board, President and Chief Executive OfficerLeonard Friedman71Secretary and DirectorFrank Georgiou58DirectorChris Theoharis56DirectorMarvin Maslow71Chairman EmeritusThere are no family relationships among any of our directors or officers.
As of December 31, 2008, the size of our Board of Directors is currently fixed at four members. Members of the Board serve until the next annual meeting of stockholders and until their successors are elected and qualified. Officers are appointed by and serve at the discretion of the Board.
None of our directors or executive officers has, during the past five years:
·
been convicted in a criminal proceeding and none of our directors or executive officers is subject to a pending criminal proceeding,
·
been subject to any order, judgment, or decree not subsequently reversed, suspended or vacated of any court of competent jurisdiction, permanently or temporarily enjoining, barring, suspending or otherwise limiting his involvement in any type of business, securities, futures, commodities or banking activities, or
·
been found by a court of competent jurisdiction (in a civil action), the Securities and Exchange Commission or the Commodity Futures Trading Commission to have violated a federal or state securities or commodities law, and the judgment has not been reversed, suspended, or vacated.
EMMANUEL TSOUPANARIAShas served as our chief executive officer and chairman of the Board since November 1, 2007.  Mr. Tsoupanarias is the president, founder and editor of FuelCellsWorks.com, a weekly trade publication that has become the voice of the fuel cell industry. He is internationally recognized as an expert in fuel cell development.  Prior to his tenure at FuelCellsWorks.com. Mr. Tsoupanarias was an executive in the power generation manufacturing sector. From 1992 to 2007 Mr. Tsoupanarias has served as a Project Manager in the power generation sector and from 2000 has served as a consultant in the fuel cell industry.

LEONARD FRIEDMANhas served as a director since October 2007.  Mr. Friedman is an honors graduate of Hunter College with a B.S. degree in economics and a minor in accounting.  He is also a graduate of Brooklyn Law School.  Mr. Friedman was a founder and partner in the law firm of Anes, Friedman, Leventhal & Rubin from which he retired in 2000.  Until 2002, he was CEO of Fiasco of New York, Inc., a restaurant and real estate corporation that owned and operated eight restaurants in New York and California.

FRANK GEORGIOUhas served as a director since October 2007.  Since 1993, Mr. Georgiou has been the President of Three Diamond Diner Corp., a private company that owns and operates the Mount Kisco Coach Diner.  He is the former President of the Upper New York Pangregorian, a consortium of restaurant owners.

CHRIS THEOHARIS has served as a director since October 2007.Since 2003, Mr. Theoharis has worked as a consultant, both advising companies on small business acquisitions and business practices in the retail industry.  He currently works as a consultant for Maximum Quality Foods Inc., a northeast regional food distribution business which serves the independent retail industry as well as the institutional portion of the food industry.  Mr. Theoharis has also served as a consultant to Vested Business Brokers.  Prior to his work in the consulting industry, he worked as a stockbroker and financial advisor for Morgan Stanley from 1996 to 2003, leaving Morgan Stanley as an Associate Vice President status.  Mr. Theoharis has also worked for a public accounting firm and owned his own food distribution business.  He graduated from Adelphi University in 1970 with a Bachelors of Business Administration in Accounting (B.B.A.).

MARVIN MASLOW served as the CEO of Manhattan Scientifics from January 1998 until November 2007. From June 1990 through September 1996, Mr. Maslow served as chief executive officer of Projectavision, Inc., a company he co-founded to develop and market video projection technology. Since November 1996, Mr. Maslow has served as chief executive officer and chairman of the board of Tamarack Storage Devices, Inc. From 1999 through 2002, Mr. Maslow served as a director of NMXS.com, Inc. For more than 20 years, Mr. Maslow has been President of Normandie Capital Corp., a private investment and consulting company. Mr. Maslow is credited with the starting up and financing of more than 20 enterprises during his career. Mr. Maslow received an A.A.S. degree from the Rochester Institute of Technology in 1957 and an honorable discharge from the U.S. Army Signal Corps in 1963. Mr. Maslow is the special advisor to the Board of Directors of
Manhattan Scientifics, Inc., a publicly traded company which is also one of our shareholders.  Mr. Maslow resigned in October 2007.  He now serves us as a non-executive chairman.
SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE
Section 16(a) of the Securities Exchange Act of 1934 requires our executive officers and directors, and persons who own more than ten percent of our common stock to file reports of ownership and change in ownership with the Securities and Exchange Commission and the exchange on which the common stock is listed for trading. Executive officers, directors and more than ten percent stockholders are required by regulations promulgated under the Exchange Act to furnish us with copies of all Section 16(a) reports filed. Based solely on our review of copies of the Section 16(a) reports filed for the fiscal year ended December 31, 2008, we believe that our executive officers, directors and ten percent stockholders complied with all reporting requirements applicable to them.
CODE OF ETHICS
On March 31, 2005, we adopted a code of ethics that applies to our principal executive officer, principal financial officer, principal accounting officer or controller, or persons performing similar functions.

19

ITEM 11. EXECUTIVE COMPENSATION
The following tables set forth all compensation awarded by us to our executive officers for the fiscal years ended December 31, 2006, 2007 and 2008.  We do not have employment agreements with any of our officers.

NameYearSalary ($)Bonus ($)Stock Awards ($)Option Awards
($)Non-Equity Incentive Plan Compensation ($)Changes in Pension Value and Nonqualified Deferred Compensation Earnings
($)All Other Compensation ($)Total
($)Emmanuel Tsoupanarias CEO and Chairman-----2007100,000--(1) 49,768--(2) 284,002433,7702008100,000----100,000Marvin Maslow 
Chairman Emeritus2006(3) 225,000-(4) 600,000---48,000873,0002007(3) 183,340--(5) 119,093---302,4332008---(6) 861,667---861,667(1)
In November 2007, a warrant for 800,000 shares of common stock with an exercise price of $0.013 was granted.  The value of this option totaled $49,768 which was valued using the Black-Scholes option pricing model.
(2)
In May 2007, 14,200,106 shares of common stock were issued for services rendered before appointment as a director and officer.
(3)
All salary earned for these years by Marvin Maslow was deferred and accrued.  The deferred salary for the years ended December 31, 2005 and 2006 was settled and written off.
(4)
In May 2006, stock awards of 10,000,000 shares were made to Marvin Maslow.
(5)
In March 2007, an option for 10,000,000 shares of common stock with an exercise price of $0.014 was granted for services previously provided.  The value of this option totaled $109,982 which was valued using the Black-Scholes option pricing model. In October 2007, warrants for 800,000 shares of common stock with an exercise price of $0.013 were issued.  The value of these warrants totaled $9,111 which were valued using the Black-Scholes option pricing model.
(6)
In January 2008, we granted options for 15,000,000 shares of common stock with an exercise price of $0.013.  The value of these options approximated $861,667 which was valued using the Black-Scholes option pricing model based upon the following assumptions: stock price of $0.06 at grant date; 5 year term; volatility of 144%; and discount rate of 4.5%.
Our officers and directors do not presently receive any cash compensation from us for their service as officers and/or directors, except for equity in the form of stock options in lieu of cash, at the discretion of our Board of Directors.
BOARD OF DIRECTORS INTERLOCKS AND INSIDER PARTICIPATION IN COMPENSATION DECISIONS
None.


20

OUTSTANDING EQUITY AWARDS

Option AwardsNameGrant DateNumber of Securities Underlying Unexercised Options (#) ExercisableEquity Incentive Plan Awards: Number of Securities Underlying Unexercised Unearned Options (#)Number of Securities Underlying Unexercised Options (#) Unexercisable (1)Option Exercise Price
($)Option Expiration DateMarvin Maslow, Chairman Emeritus3/7/2007
1/5/200810,000,000
15,000,000-
--
-$
$0.0135
0.01303/7/2017
1/5/2019

Warrant AwardsNameGrant DateNumber of Securities Underlying Unexercised Warrants (#) ExercisableEquity Incentive Plan Awards: Number of Securities Underlying Unexercised Unearned Warrants (#)Number of Securities Underlying Unexercised Warrants (#) Unexercisable (1)Warrant Exercise Price
($)Warrant Expiration DateEmmanuel Tsoupanarias, Chairman and CEO11/9/2007800,000--$0.01311/9/2017Marvin Maslow, Chairman Emeritus10/11/2007800,000--$0.01310/11/2017Leonard Friedman, Director10/11/2007800,000--$0.01310/11/2017Frank Georgiou, Director10/11/2007800,000--$0.01310/11/2017Chris Theoharis, Director10/11/2007800,000--$0.01310/11/2017
21

ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS
The following table sets forth, as of December 31, 2008, the names, addresses and number of shares of common stock beneficially owned by (i) all persons known to us to be the beneficial owners of more than 5% of the outstanding shares of common stock, (ii) each of our directors, (iii) each of our executive officers, and (iv) all of our directors and executive officers as a group. Except as indicated, each beneficial owner listed exercises sole voting power and sole dispositive power over the shares beneficially owned. Share ownership in each case includes shares issuable upon exercise of options exercisable within 60 days of the date of this Annual Report that would be required to be reported pursuant to Rule 13d-3 of the Securities Exchange Act of 1934 for purposes of computing the percentage of common stock owned by such person but not for purposes of computing the percentage owned by any other person. Unless otherwise
indicated, the address of the below-listed persons is our address, 405 Lexington Avenue, 32nd Floor, New York, New York 10174.

Name and Address of Beneficial OwnerNumber of Shares Beneficially OwnedPercent of Class(1)Marvin Maslow (2)58,767,60614.4%Emmanuel Tsoupanarias (3)15,250,1064.0%Leonard C. Friedman (4)7,500,0002.0%Frank Georgiou (5)25,000,1066.6%Chris Theoharis (6)5,000,1051.3%Directors and Executive Officers as a group (5 persons)113,517,92327.2%
(1)
This tabular information is intended to conform with Rule 13d-3 promulgated under the Securities Exchange Act of 1934 relating to the determination of beneficial ownership of securities.  The percent of class is based on 378,977,926 shares and, for each beneficial owner, gives effect to the exercise of warrants or options exercisable within 60 days of the date of this table owned, in each case, by the person or group whose percentage ownership is set forth herein.

(2)
Includes 28,947,606 shares of Common Stock, options to purchase 25,000,000 shares of Common Stock, a warrant to purchase 800,000 shares of Common Stock and 2,400,000 shares of Common Stock owned by his son and 1,120,000 shares of Common Stock owned by Mr. Maslow's wife and son.

(3)
Includes 14,200, 106 owned by Saraklis Inc, a corporation controlled by Mr. Tsoupanarias and a warrant to purchase 800,000 shares at a price of $0.013 per share.

(4)
Includes a warrant to purchase 800,000 shares at a price of $0.013 per share.

(5)
Includes 2,500,000 shares of Common Stock owned by his son and a warrant to purchase 800,000 shares at a price of $0.013 per share.

(6)
Includes a warrant to purchase 800,000 shares at a price of $0.013 per share.


22

ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS AND DIRECTOR INDEPENDENCE
As of December 31, 2008, we have loans payable of $450,000 and $545,000 payable to our former Chief Operating Officer and former Chief Executive Officer.  The loans bore interest at 5.5% per annum and were initially due December 31, 2002 and have been mutually extended and settled.  Under the terms of the settlement, dated December 12, 2007, the loans bear interest at 5% per annum and are now fully due on demand.  We have recorded interest expense for notes payable to these former officers of approximately $50,000 and $61,000 for the years ended December 31, 2008 and 2007, respectively.  Accrued interest related to these notes payable approximated $281,750 and $232,000 as of December 31, 2008 and 2007, respectively.  In May 2007, we issued 14,200,106 shares of common stock to its former Chief Executive Officer for settlement of debt totaling $71,000.  As part of the settlement in December 2007, the former Chief
Operating Officer and former Chief Executive Officer collectively forgave $1,416,500 of their outstanding accrued salaries ($1,387,500) and note payable ($29,000) balances.  The amount forgiven has been accounted for as contributed capital.  Additionally, we repaid $5,000 of the former Chief Executive Officers note payable balance.  The remaining unpaid note payable balances totaling $995,000 at December 31, 2008 are due on demand, unsecured and accrue interest at five percent (5%) per annum.
Teich, Beim & Moro, P.C., an accounting firm in which Mr. Teich, our former treasurer and a director, is a principal, received approximately $48,000 and $35,000 of compensation for accounting services rendered to us during the years ended December 31, 2008 and December 31, 2007, respectively.
Weisner LLP, an accounting, professional services firm in which Mr. Anderson, our former director, was a partner, received approximately $9,000 of compensation for accounting services rendered to us during the year ended December 31, 2007.

ITEM 14. PRINCIPAL ACCOUNTANT FEES AND SERVICES

INDEPENDENT AUDITOR FEES

The following is a summary of the fees billed to us by our independent auditors for the fiscal year ended December 31, 2008 and December 31, 2007:

Fee CategoryFiscal 2008Fiscal 2007Audit fees$50,000$89,750Tax fees--Other fees--Total fees$50,000$89,750
Audit Fees. Consists of aggregate fees billed for professional services rendered for the audit of our consolidated financial statements and review of the interim consolidated financial statements included in quarterly reports and services that are normally provided by our auditors in connection with statutory and regulatory filings or engagements.

Tax Fees. Consists of aggregate fees billed for professional services for tax compliance, tax advice and tax planning. These services include assistance regarding federal and state tax compliance.

Other Fees. Consists of fees for products and services other than the services reported above. There were no management consulting services provided in fiscal 2007 or 2006.

We do not currently have an Audit Committee. Our full Board of Directors considers whether the provision of these services is compatible with maintaining the auditor's independence, and has determined such services for fiscal 2005 and 2006 were compatible.

BOARD OF DIRECTORS POLICY ON PRE-APPROVAL OF SERVICES OF INDEPENDENT AUDITORS

The Board of Directors policy is to pre-approve all audit and permissible non-audit services provided by the independent auditors on a case-by-case basis. These services may include audit services, audit-related services, tax services and other services.

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ITEM 15. EXHIBITS

(a) EXHIBITS

Exhibit
Number
Description of Exhibit
----------   ----------------------
2.1
Agreement and Plan of Reorganization (1)
2.2
Agreement and Plan of Merger (1)
3.1
Certificate of Incorporation (1)
3.2
Amendment to Certificate of Incorporation (1)
3.3
Bylaws (1)
4.1
Amended Certificate of Designation, Preferences and Rights of Series C Preferred Stock (2)
10.1
License/Assignment Agreement with Robert Glenn Hockaday, and DKY, Inc. (1)
10.2
Research and Development Agreement with Energy Related Devices, Inc. (1)
10.3
Letter Agreement with Energy Related Devices, Inc. and Robert Glenn Hockaday (1)
10.4
Intellectual Property Assignment and Research and Development Agreement with
Novars Gesellschaft fur neue Technologien GmbH (1)
10.5
License Option Agreement with The Regents of the University of California (1)
10.6
Manhattan Scientifics, Inc. 1998 Stock Option Plan (1)
10.7
Employment Agreement with Robert Hermes (1)
10.8
Agreement with Stanton Crenshaw Communications (1)
10.9
Agreement with Equilink (1)
10.10
Stock Purchase Agreement between Manhattan Scientifics, Inc., Projectavision, Inc., and Lancer Partners, L.P. (3)
10.11
License Option Agreement with Mr. Edward Vanzo (4)
10.12
Manhattan Scientifics, Inc. 2000 Equity Incentive Plan (5)
10.13
2004 Consultant Stock Plan (6)
10.14
Loan Agreement with Oro Valley Associates, LLC (7)
10.15
Warrant Agreement with Oro Valley Associates, LLC (7)
10.16
Manhattan Scientifics 2005 Equity Incentive Plan  (8)
21.1
List of Subsidiaries (3)
31.1
Certification of Principal Executive Officer Pursuant to Rule 13a-14(a) and 15d- 14(a)(9)
31.2
Certification of Principal Financial Officer Pursuant to Rule 13a-14(a) and 15d- 14(a)(9)
32.1
Certification Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act
of 2002(9)
---------------(1)
Incorporated by reference to the registrant's Form 10-SB filed with the Commission on December 8, 1999.
(2)
Incorporated by reference to the registrant's Form 10-QSB filed with the Commission on August 14, 2000 for the period ended June 30, 2000.
(3)
Incorporated by reference as Amendment No. 2 to the registrant's Form 10-SB filed with Commission on February 9, 2000.
(4)
Incorporated by reference to Amendment No. 3 to the registrant's Form 10-SB filed with the Commission on March 29, 2000.
(5)
Incorporated by reference to the registrant's registration statement filed on Form S-8 filed with the Commission on September 14, 2001.
(6)
Incorporated by reference to the registrant's registration statement filed on Form S-8 filed with the Commission on November 26, 2004.
(7)
Incorporated by reference to the registrant's Form 10-KSB filed with the Commission on April 15, 2005.
(8)
Incorporated by reference to the registrant's registration statement filed on Form S-8 filed with the Commission on June 8, 2005.
(9)
Filed herewith.


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SIGNATURES

In accordance with Section 13 or 15(d) of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned, thereunto duly authorized on this 4th day of May 2009.

MANHATTAN SCIENTIFIC, INC.By:/s/ Emmanuel TsoupanariasEmmanuel TsoupanariasChief Executive Officer
In accordance with the Exchange Act, this report has been signed below by the following persons on May 5, 2009, on behalf of the registrant and in the capacities indicated.


SignatureTitle/s/ Emmanuel TsoupanariasChief Executive Officer,Emmanuel TsoupanariasPresident, Chairman of the Board/s/ Leonard FriedmanSecretary and DirectorLeonard Friedman/s/ Frank GeorgiouDirectorFrank Georgiou/s/ Chris TheoharisTreasurer and DirectorChris Theoharis