\ -. I 

# - L. d 

### DP

# 'BARCODE:
CASE: SUBMISSION: ,

, Dl88115 016380 DATA E5435262 BEAN SHEET Page 1 of 1 

## * * 

## * CASE/SUBMISSION INFORMATION

## * 

## * * CASE TYPE: REGISTRATION ACTION: 100 NC-FOOD/FEED USE CHEMICALS: 097805 Deltamethrin 2.8600% ID#: 034147-1 DECIS INSECTICIDE COMPANY: 034147ROUSSEL UCLAF I PRODUCT MANAGER: 13 GEORGE LAROCCA 703-305-6100 ROOM: CM2 204 PM TEAM REVIEWER: JOHN HEBERT 703-30,5-5419 ROOM: CM2 202 RECEIVED DATE: 02/12/93 DUE OUT DATE: 08/21/93 

## * * * DATA PACKAGE INFORMATION

## * * 

## *
DP BARCODE: 188115 EXPEDITE: N DATE SENT: 02/12/93 DATE RET.: 

### / / CHEMICAL: 097805 Deltamethrin DP TYPE: 001 Submission Related Data Package ADMIN DUE DATE: 06/12/93 CSF: N 1 LABEL: N ASSIGNED TO 

# @PC DATE OUT DIV : EFED BRAN: EEB 

### / 

### / / / 

### 85 

## 4(/

## (3 SECT: 

### / / / DUE-3, /IT

## j54- 

# - REVR : 

### / 

### / / 

### / 

# zc, f=& J77-575 :-'~:y& ~-+,i C-, CONTR: 

### / / / / --.--.

## - 

## * * * DATA REVIEW INSTRUCTIONS

## * * *
EFED HAS PASSED THE SCREENING OF NEW CHEMICAL. THE DATA/CHEMICAL SHOULD BE PLACED IN FULL REVIEW. DATA HAS BEEN IN YOUR SECTION SINCE 9-29-92 WHEN PACKAGEWAS SUBMITTED FOR SCREENING.



## * * * ADDITIONAL DATA PACKAGES FOR THIS SUBMISSION

## * 

## * *
DP BC BRANCH/SECTION IIATE-OUT DUE BACK INS CSF LABEL 188114 TSCB 02/12/93 06/12/93 Y N N 188116 EFGB 02/12/93 06/12/93 J! Y 

### Y 188172 TB-1 02/12/93 06/12/93 Y N NChemical:Deltame*h 100.0 Submission Purpose and Label Information:

, 100.1 Submission Purpose:

\ Hoescht Roussel has requested full registration of deltamethrin, active ingredient of Decis 0.2 EC Insecticide for use on field cotton nationwide. Decis insecticide has been used on cotton under experimental use permits since 1991. This use was on small plots(50 acres) and limited to approximately 1000 acres total in 14 states. , Cotton production in the U.S. is primarily concentrated in the south central and southwestern states. Total grown nationwide exceeds 9,826,000 acres (basedon 1987 Ag. Census). Major cotton growth states listed in the census includeAla., Ariz., Ark., Ca., Fla., Ga., Idaho, Ill., Ind., Iowa, Ls., ~iss.,Ms., N.M., N.\C., Okla., S.C., Tenn and Texas.

L / 100.2 Fo,rmulation Information Active Ingredient: (IR, 3~)-392,2-dimethylcyclopropanecarboxzylic acid (s)-a-cyano-3-phenoybenzyl ester ................................................2.86%* Inert Ingredients:

# ......................... 97.14% I Total 100%

, *Equivalent to 0.2 lb active ingredient per U.S. gallon. 100.3 Application Methods:Decis 0.2 EC Insecticide 1 ) Application would be made on an as needed basis depending on insect populations and weather conditions. General Information: Dilute Decis Insecticide in water or at least once-refined crop oil according to the directions and use as a foliar spray at rates listed below. Uniform coverage is essential. Begin applications when economic infestations occur based on local information and repeat as needed (observethe restrictions in Note 2). Do not enter the treated field before spray is dried.

1

- - __;"l"-l"-^- - """ ~ b wa,z*>=%,=# L"

### -- -Application Rates: 

### 0.013 to 0.020 lbs ai/A (8.32 to 12.8 F1. oz/A) 1, 

### Do not applymore than ten (10) applications (0.2 pound of active ingredientper acre or 128 fluid ounces/A) per growing season. 2. 

### Do not apply through irrigation system, 3. Do not graze treated forage.

i 100.4 Target Organisms: 

### Boll weevil, cotton bollworm, leafperforator, fall armyworm looper, tobaccobudworm. cotton fleahopper, cotton pink bollworm, soybean

100.5 Precautionary Labeling: 

### "Thispesticide is toxic to fish and aquatic invertebrates. Do not apply directly towater,'toareaswhere surface water ispresent, or to intertidal areasbelow themean high water mark. Drift and runoffmay be hazardous to aquatic organisms in areas near the application site. Do not contaminate water when disposing of equipment washwaters or rinsate. Thispesticide ishighly toxic tobees exposedfto direct treatment. Do not apply it or allow it to drift to crops orweeds onwhich bees are actively foraging. Notify Stateand/or Federal authorities and Hoechst-Roussel' Agri-Vet company immediately if you observe any adverse. environmental effects due to the use of ~ecis Insecticide. Notice: '1t is a federal offense touse any pesticide in manner that results in the death of a member of an endangered species. ,SprayDrift Precautions for CottonUse

1. 

### All aerial and ground application equipment must be properly maintained and calibrated using appropriate carriers. 2. 

### Do notmake aerial or ground applications during temperature inversions. 3, 

### Make aerial or ground applicationswhen thewind velocity favors on-targetproduct deposition

(approximately 3 

### to 10

### mph). Do not applywhen wind velocity exceeds 15

### mph. 4, 

### Donot apply by groundwithin 25 feet, orby airwithin 75 

### feet of lakes; reservoirs; rivers, permanent 2

--- ---. - - - - Q\ streams, marshes or natural ponds,-estuariesand commercial fish farm ponds. 5. For aerial applications, the spray boom must bemounted on the aircraft so as tominimize drift caused by wingtip'or rotor vortices. Boom length must not exceed 75% of wing span or rotor diameters.

6. Do not make more than a total of 10 synthetic pyrethroid applications (of one product or combination of products) to a cotton crop in one growing season. Synthetic pyrethroid products include Ambusho, Ammoo, Asanao, 

### XL, Baythroido, Captureo, ~ymbush~, Fury0, Karateo, 

### ounce^, and Scouto.
101.0 Hazard Assessment:In view of the large acreage involved cotton production areas are expected to oEfer exposure potential to 

### a most types of habitats found in lowland areas of theniajor cotton producing states. Recently the Agency has discussed possible mitigation measures for pyrethroids presently under conditional registration for use on cotton. 101.1 Discussion: Environmental Fate Characteristics: ~nvironmentalfate data for deltamethrin is not complete at this time. The parent compound, Tralomethrin, has been studied with some detail in regard to environmental fate. A limited picture of deltamethrin's behavior in the environment is possible by reviewing themonitoring for deltamethrin residues conducted in tralomethrin field studies. As an application interval is not specified a 2 day interval with 10 applications could be construed as a

. reasonable maximum application scenario. It is likely that

a larger interval would be employed in normal use patterns unless harmful insect pressure was abnormally high. Based on 0.019 lb ai/acre maximum applicatidn rate(sing1e I application) 

# ~ PPM 

# - Shortarass ~ons~rasses Leaves Seed vods Fruit / Typical 2.37 1.74 0.66 0.057 0.03 maximum 4.56 2.09 2.38' 0.23 0.13

! Maximum exposure (nodegradation) 10 applica. 45.6 20.9 23.80 2.3 1.3

3

\

### Toxicity Characteristics:

I 

### Avian Toxicity Data: 

### TheAgency has reviewed 5 

### studieswith avian species and deltamethrin. These studiesare summarizedbelow.

Avian Dietary-~allard ACC 264510 

### Core/Fulfilled ACC 262456 

### Avian Reproduction 421148-08 

### Core/Fulfilled Bobwhite quail Avian Reproduction 421148-09 

### Core/Fulfilled Mallard duck Data Requirement 

### Avian Oral-Bobwhite quail Avian Dietary- Bobwhite

Avian ~okicit~: 

### Toxicity to avianwildlife is lowwith the LDS0>2250

### mg/kg for bobwhite quail, and dietary LC,, of >10000

### ppm and >4620

### ppm for bobwhite quail and mallard duck, respectively. At the low rates of application residue levelswill not approach levels of concern for birds, despite themultiple applicationsproposed. Maximum residue levelswould be 45

### ppm with 10 

### applications and no degradation. Recently submitted avian reproduction studies no effect levels of up to 450

### ppm for bobwhite quail and mallard duck(highest doses tested). This residue level is not expected to be exceeded 

### at the proposed application rate. MRID # 

### ACC 262456 

### ACC 264510 

### ACC 262456 

### Category/Status 

### ~ore/~ulfilled Core/FulfilledAquatic organisms Toxicity: Deltamethrin demonstrates very high toxicity to all aquatic species tested to date. The A summary of acceptable aquatic toxicity data submitted to date is listed below. Unless indicated(*), these studies are considered acceptable to support this registration Deltamethrin: Aquatic Organism Toxicity Data

Bluegill/ ACC 262456 99.3 I

Daphnia magna/ACC 262456 199.3 I
I Daphnia magna/41651014 

# 1 2.54 TEP I *Daphnia magna/42114813 Tech. Fathead minnow

# - Early

I I Fathead minnow-Full Life Tech Cycle/427786801

I Sheepshead minnow/42114815 I Sheepshead minnow/42114811 25.4% TEP 

# I~~sid/42114810 

# I Tech. I Mysid/42114812 

# ITEP I 1 

# 1Eastern oyster/41651016 199.2%



## ~ I' 

# 1Eastern oyster/41651017 

# ITEP I I 

### I I 

# ~ * The Invertebrate Full Life Cycle acceptable due to the incomplete s. Result 

# II LC50 = 1.4 PPB 

# II LC50 = 0.91 PPB LC50 = 0.36 PPB LC50 = 0.25 PPB 

# II EC50 = 3.5 PPB 

# II

>.0041<0.0089 PPB 

# -1

36 Day MATC Chronic MATC >0.017<0.035 PPB

LC50 = 0.0037 PPB LC50 = 0.0017 PPB EC50(shell deposition) =12 PPB 

# 1

EC50 (shelldep.) = 17.9 PPB 

# I
Study was not fully tbmission of raw data..
I 

# I Non target aquatic organisms are highly sensitive tovery low concentrations of deltamethrin. Using a conservative 5% drift scenario from'a0.02 lbai/Acre aerial application,the 

# ~ exp'ectedEEC levels from direct drift to a shallow marsh 

## - 

# ~ area(6" deep-1 acre size) could exceed 0.73 PPB. With rapiddissipation to a 6 foot depth a direct 5% drift to a one acre waterbody could result in -an instantaneous residue level of 0.061 PPB. The estimated runoff from a ten acre field to a 6 foot 1 acre body of water could reach'0.12 PPB with a 1% runoff of the applied chemical(sing1e application). Due to high adsorption characteristics, much of material may reach habitats with soil runoff. If bound to .sedimentsdeltamethrin may prove less bioavailable to midwater organisms, but more bioavailable tobenthic organisms. These EEC levels are well above acute 50% mortality levels for daphnia and mysids. They also exceed chronic effect levels of concern far fish.andinvertebrate species (EEC=LOEC). They ,areabove or equivalent to levels of concern(lll0 LC50) for all species tested to date with exception of the eastern oyster shell deposition effect levels. It is not known if larval stages of shellfish would be more sensitive than the spat. 

### Nontarget Insect Toxicity: Studies with honey bees indicate high acute contact toxicity(MR1D 42114815). The acute contact LD50 for the honey bee was determined tobe 1.5 ug/bee. In a field application studies(MR1D 42773902 and 42475905) the reported LD,,,was 0.067 ug/bee and the RTZ5for deltamethrin was determined to be less than 8 hours but greater than 2 hours for honeybees exposed to treated foliage. This indicates the the insecticide should be applied no less than 8 hours prior to expected foraging of honeybees in treated fields to reduce concerns for adverse effects from treated foliage. This data does not address the toxicity of deltamethrin to

I other species of beneficial insects, but high toxicity is expected based on thehoneybee studies and the efficacy of the product toward numerous target species. 

### Nontarget Plant Toxicity EEB presently has no data to indicate any possible phytotoxic effects of this compound. Due to it's use as an insecticide no plant testing requirements have been requested to date. However the company's disclaimer does mention that crop damage resulting from misuse will notibe

, the responsibility of Hoechst-Roussel. During microcosm testing(MR1D 42114816) wikh tralomethrin and deltamethrin a substantial percentage of total residues of deltamethrin were measured in plant tissues indicating the propensity of ,theinsecticide tobioconcentrate,in plant matter./
100.4 Endangered Species concerns: EEB does not believe that the proposed use will offer hazard to listed terrestrial avian or mammalian species as chronic and acute toxicity values fall well below predicted EEC levels. Though theAgency has not requested any recent consultation with the Dept. of Interior regarding Deltamethrin use on cotton, theAgency did receive a 1985 response from The U.S. Fish and Wildlife regarding use olf Tralomethrin on cotton. At the time the number of listed specieswas lower and therefore may not reflect the number of specieswhich might be affected by a 1994 registration of a pyrethroid on cotton. In the response theActing Associate Director made the conclusion that "the proposed registration of Tralomethrin for use on cotton is likely to jeopardize the continued existence and adversely modify associated designated critical habitats of all listed fishes and amphibianswhich occur in counties where cottrn is grown."
I I The buffer zones of 25-75 feet have not been shown by the I industry's Spraydrift Task Force to be adequate protection from possible contamination tounlisted aquatic species. 

# i Thus, the same conclusion regarding listed aquatic species 

### I will apply when they are located adjacent to cotton production sites. In order to avoid violations of the 

# 1

~i Endangered Species Act through contamination of critical I aquatic habitats or endangered terrestrial insect habitats, it is recommended that thorough research into locations of * any potentially exposed critical habitat sites and their t proximity to the proposed application sites be conducted by , 

### i the responsible parties involved with any cotton use of 

## /F deltamethrin. EEB cannot dismiss the possibility of I, exposure of endangered aquatic species from the proposed label precautions. The table provided on the following pages lists endangered fish, amphibian, aquatic i. reptile(excepting sea turtles), and aquatic invertebrate 

# i species for major cotton production states in the U.S.Listed Freshwater Aquatic species

# - Major Cotton Crop States As of October 1992

I species 

# 1 8tates(counties)

Cahaba shiner ( Alabama(Bibb,Shelby) I I 

# N , Gulf sturgeon
'~labamaredbellyturtle ALabama(Balduin), Florida(Escambia,Okaloosa,Santa Rosa,Wal ton, Jackson), Georgia(Decatur,Seminole), and Mississippi(Hinds, Rankin) Alabama(Ba1duin)

Blueshiner ~lattened musk turtle Red Hillssalamander Pygmy sculpin

Rough pigtoepearlymussel Alabama(Colbert, LauderdaPe, Madison, Marshall, Morgan) I 

# II

Alabama(Calhoun, Cherokee) Alabama(Fayette, Marshall, Tuscaloosa) Alabama(Conecuh, Covington, Monroe) Alabama(Ca1houn) UplandCombshell clam Tulotoma snail Southern acornshell Pinkmucket pearlymussel -

Dark pigtoemussel Alabama(Blount, Tuscaloosa) White uartyback pearlymussel ALabama(Colbert, Lauderdale) Ovate clubshell clam .ALabama(Dallas, Lamar, Macon, Perry, Pickens, Tuscaloosa), and Georgia(Bartow) Southernclubshell Alabama(Dallas, L,amar,Macon,Perry,Shelby, Tuscaloosa) Penitent mussel Alabama(Lamar) andMississippi(ltamba, Loundes, Monroe) Triangular kidneyshell Alabama(B1ount) andGeorgiaCBartou) Stirrupshell Alabama(Pickens) \ Alabama cavefish, Alabama(Colbert, Lauderdale) Gold1ineDarter ALabama(Bibb, Shelby) Slackuaterdarter Alabama(Lauderdale, Limestone) andTennessee(Lawrence) Orange footedpearlymsel Alabama(Colbert, Lauderdale, Madison, Marshall, Morgan) Alabama mocassinshell mussel ~eorgia(~artou) Boulder darter Alabama(Limestone) Snaildarter . Alabama(Limestone, Marshall, Morgan) andTenneseeCLincoln) Tan riffleshell clam Alabama(Madison) Alabama cave shrinp Alabama(Madison) Finelinedpocketbook mussel Alabama(Bibb, ~il las, Elmore) Judge Tait's mussel Alabama(Pickens) and~ississippi(ltauaba,Loundes, Monroe) ALabama(Bibb, Shelby) and Georgia(Barstou) Alabama(Calhoun, Shelby) AlabamaCCherokee) Alabama(Colbert, Lauderdale, Limestone, Madison, Marshall, Morgan), Missouri(Butler), Arkansas(Clay, Desha, Woodruf) and Kentucky(Canpbel1)ale, Shelby, Tipton)
Fat pocketbook mussel-1I

*

Cape Fear shiner Roanoke Logperch Fountaindarter , Dwarf wedge mussel Pecos gambusia Pecos bluntroseshiner Boulderdarter Boirduingpearlymussel Cracking pearlymussel Cunberlandmonkeyface mussel Fine rayedpigtoe pearlymussel Shiny pigtoepearlymussel Concho uatersnake Houstontoad ,

Prairiemole cricket Kretsmarr cove moldbeetle Tooth cave groundbeetle Bee creek harvestman spider Tooth cave pseudo scorpion Tooth cave spider I NorthCarolina(Harnett) Virginia(Greensvil1e) Texas(Calduell1 NorthCarolina(Johnston, Nash, Wilson) New Mexico(Chaves, Eddy) andTexas(Reeves) New Mexico(Chaves, Eddy) Tennessee(Linco1n) Tennessee(Linc0ln) Tennessee(Linco1n) Tennessee(Limo1n) Tennessee(Linc0ln) 'lennessee(Linco1n) Texas(Brown, Coleman, Concho, Runnels, Tom Green) Texas(Burleson, Fs. Bend, Lavaca, Leon, Milan1

Oklahoma TexasCTravis, Williamson) Texas(Travis, Ui1Liamson) Texas(Travis, Ui11iamson) Texas(Travis, Ui1Liamson) Texas(Travis, Williamson) 101.2 Adequacy 

### of Data: 

### Acute data submitted to date to support registration of ~eltamethrin is adequate for purposes of this proposed registration. Fish and invertebrate full life cycle testing has indicated that adverse effects to reproductive success of these groups may occur at concentrations ranging from 0.0041 ug/L-to0.0089 ug/L for invertebrates and 0.017 to 0.035 ug/L for fish species exposed to deltamethrin residues. To date ' 

### the Branch has not reviewed data which would eliminate concern that these levels will be reached in the environment from labeled rates and use patterns. 

### A summary of all data submitted and reviewed to date is attached to this review., 101.3 Adequacy 

### of Labeling: The label presented with this 

# ~
- 

### registration proposal does not include adequate precautionary I 

# . measures toprevent or runoff drift to adjacent aquatic or 

# ~ \ 

### critical terrestrial habitats. The label should incorporate I 

### mitigatory precautions recently agreed to at recent Agency I I 

### meetings with The Cotton Council. These precautions include the following:
I 

### 10

-------- -- - - 

### -- "> ---

# .. **

I
1. A ten foot vegetative buffer zone near non-target habitat., 2. A -150foot buffer between aquatic habitats and aerially treated fields(Non ULV applications).

. 3. In the case of ULV spray applications a 450 foot buffer zone is suggested.
C 4. Restriction of boom length to 70% or the limit of efficay, 4 5. Spray nozzle pressure of 45 PSI or less.

102.0 Conclusions: EEB has completed it's risk assessment for deltamethrin use on cotton. Based on the available information EEB concludes that the proposed use poses serious risk to exposed aquatic organisms or nontarget beneficial insects. Many cotton production sites are expected to be located adjacent to some type of aquatic habitat. Without further precautiohs against drift contamination (suchas application only when wind direction is away from nontarget aquatic habitats), EEB cannot dismiss the possibilit,~ of hazard to aquatic species located in waters adjacent to application sites. The effects of drift to populations of pollinating beneficial insects may also be extreme unless applications are made at times of low activity (foraging) for these species. Endangered species conce,rnsmust be addressed on a site by site basis in relation to the ecological risk factor involved with that particular site location(ie. proximity to critical habitat).

I Reviewed by: Brian Montague, Fisheries Biologist

I Ecological Effects Branch

, Environmental Fate and Effects Division

I

I I
11 I Approved 

### by: Les Touart, Supervisory Biologist 

# ~ Ecological Effects Branch Environmental Fate and Effects Division 

# I Approved 

### by: 

# I ;I (H7507C) 

### I 

# 18. 

### .*

I

I I I

, 4

I 

### ~eltamethrin Data Test Requirement 71-1 

### Avian Oral 71-1 

### Avian Oral TEP

,71-2 

### Avian Dietary Gamebird

71-2 

### Avian Dietary ~amebird TEP 71-2 

### Avian Dietary Waterfowl 71-2 

### Avian Dietary Waterfowl TEP 71-3 

### Wild Mammal Toxicity 71-4 

### Avian ReproductionGamebird 71-4 

### Avian Reproduction Waterfowl 71-5 

### Terrestrial Field Study 72-1 

### Warmwater Fish Acute Tox 72-1 

### Warmwater FishAcute Tox TEP 72-1 

### Coldwater Fish Acute Tox 72-1 

### Coldwater Fish Acute Tox TEP 72-2 

### Freshwater InvertebrateTox 72-2 

### FW Invertebrate Tox TEP 72-3 

### Estuarine/Marine Fish Acute

I 

# 1

1 1 

# ~I I 

# I-- I 1 II 

## I i I 

# I1 I 

## I f 

### Requirement submission 262456

264510/262456

264510/262456

- 421148-08 421148-09

262456 41651012 262456 41651013 262456 41651014 41651015

72-3 

### Estuar/Marine ShrimpAcute 72-3 

### Estuar/Marine Shrimp TEP 72-3 

### Estuar/Marine Mollusc Acute 72-3 

### Estuar/Marine Mollusc TEP 72-4 

### Early Life Stage Fish 72-4 

### Life Cycle Aquatic Inverteb. 72-5 

### Full Life Cycle Fish 72-7 

### Aquatic Field StudyMicrocosm 122-1 

### Tier 

### ITerrestrial Plants

, 122-2 

### Tier 

### IAquatic Plants
, 123-1 

### Tier I1Terrrestrial Plants 123-1 

### Tier I1g qua tic 

### Plants 141-1 

### Nontarget InsectAcute 141-2 

### Nontarget Insect ~oliar I I I 

### Status Status Fulfilled Not required Fulfilled Not required Fulfilled Not required Not required ~ulf illed Fulfilled Not required Fulfilled Fulfilled Fulfilled ~ulf illed ~ulfilled Fulfilled ~ulf illed Fulfilled

II 421148-10 421148-12 41651016 41651017 421148-14 421148-13 427868021 41148016

421148-15 424759-05 42475905 111 

### Fulfilled ~ulfilled ~ulf illed Fulfilled ~ulf illed Incomplete ;,x"; 

### Fulfilled Not required
Not required Not required Not required Not required ~ulf illed Fulfilled