38282 Federal Register / Vol. 77, No. 124 / Wednesday, June 27, 2012 / Notices 

ENVIRONMENTAL PROTECTION 

AGENCY 

[EPA–HQ–OPPT–2009–0154; FRL–9333–1] 

Final Test Guidelines; OCSPP 850 

Series; Notice of Availability 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: EPA is announcing the 

availability of the final test guidelines 

for Series 850—Ecological Effects Test 

Guidelines, consisting of Groups B, C, 

D, and F. These test guidelines are part 

of a series of test guidelines established 

by Office of Chemical Safety and 

Pollution Prevention (OCSPP) for use in 

testing pesticides and chemical 

substances to develop data for 

submission to the Agency under the 

Toxic Substances Control Act (TSCA), 

the Federal Insecticide, Fungicide and 

Rodenticide Act (FIFRA), and section 

408 of the Federal Food, Drug and 

Cosmetic Act (FFDCA). As guidance 

documents, the test guidelines are not 

binding on either EPA or any outside 

parties. 

FOR FURTHER INFORMATION CONTACT: For 

general information contact: Melissa 

Chun, Regulatory Coordination Staff 

(7101M), Office of Chemical Safety and 

Pollution Prevention, Environmental 

Protection Agency, 1200 Pennsylvania 

Ave. NW., Washington, DC 20460–0001; 

telephone number: (202) 564–1605; 

email address: chun.melissa@epa.gov. 

For technical information contact: 

Amy Blankinship, Environmental Fate 

and Effects Division (7507P), Office of 

Pesticide Programs, Environmental 

Protection Agency, 1200 Pennsylvania 

Ave. NW., Washington, DC 20460–0001; 

telephone number: (703) 347–8062; 

email address: 

blankinship.amy@epa.gov, or Kathryn 

Gallagher, Risk Assessment Division 

(7403M), Office of Pollution Prevention 

and Toxics, Environmental Protection 

Agency, 1200 Pennsylvania Ave. NW., 

Washington, DC 20460–0001; telephone 

number: (202) 564–1398; email address: 

gallagher.kathryn@epa.gov. 

SUPPLEMENTARY INFORMATION: 

I. Introduction 

These test guidelines are part of a 

series of test guidelines established by 

OCSPP for use in testing pesticides and 

chemical substances to develop data for 

submission to the Agency under TSCA 

(15 U.S.C. 2601 et seq.), FIFRA (7 U.S.C. 

136 et seq.), and section 408 of FFDCA 

(21 U.S.C. 346a). 

The test guidelines serve as a 

compendium of accepted scientific 

methodologies and protocols that are 

intended to provide data to inform 

regulatory decisions under TSCA, 

FIFRA, and/or FFDCA. The test 

guidelines provide guidance for 

conducting the test, and are also used by 

EPA, the public, and the companies that 

are subject to data submission 

requirements under TSCA, FIFRA, and/ 

or FFDCA. 

As guidance documents, the test 

guidelines are not binding on either 

EPA or any outside parties, and EPA 

may depart from the test guidelines 

where circumstances warrant and 

without prior notice. At places in this 

guidance, the Agency uses the word 

‘‘should.’’ In this guidance, use of 

‘‘should’’ with regard to an action 

means that the action is recommended 

rather than mandatory. The procedures 

contained in the test guidelines are 

recommended for generating the data 

that are the subject of the test guideline, 

but EPA recognizes that departures may 

be appropriate in specific situations. 

Alternatives to the recommendations 

described in the test guidelines may be 

proposed, and the Agency will assess 

them for appropriateness on a case-bycase basis. 

II. General Information 

A. Does this action apply to me? 

This action is directed to the public 

in general. Although this action may be 

of particular interest to those persons 

who are or may be required to conduct 

testing of pesticides and chemical 

substances for submission to EPA under 

TSCA, FIFRA, and/or FFDCA, the 

Agency has not attempted to describe all 

the specific entities that may be affected 

by this action. If you have any questions 

regarding the applicability of this action 

to a particular entity, consult the 

technical person listed under FOR

FURTHER INFORMATION CONTACT. 

B. How can I get copies of this document 

and other related information? 

1. Docket for this document. The 

docket for this action, identified by 

docket identification (ID) number EPA– 

HQ–OPPT–2009–0154, is available at 

http://www.regulations.gov or at the 

Office of Pollution Prevention and 

Toxics Docket (OPPT Docket), 

Environmental Protection Agency 

Docket Center (EPA/DC), EPA West 

Bldg., Rm. 3334, 1301 Constitution Ave. 

NW., Washington, DC. The Public 

Reading Room is open from 8:30 a.m. to 

4:30 p.m., Monday through Friday, 

excluding legal holidays. The telephone 

number for the Public Reading Room is 

(202) 566–1744, and the telephone 

number for the OPPT Docket is (202) 

566–0280. Please review the visitor 

instructions and additional information 

about the docket available at http:// 

www.epa.gov/dockets. 

2. Electronic access to OCSPP test 

guidelines. To access OCSPP test 

guidelines electronically, please go to 

http://www.epa.gov/ocspp/pubs/frs/ 

home/testmeth.htm. You may also 

access the test guidelines at http:// 

www.regulations.gov grouped by series 

under docket ID numbers: EPA–HQ– 

OPPT–2009–0150 through EPA–HQ– 

OPPT–2009–0159 and EPA–HQ–OPPT– 

2009–0576. 

III. Overview 

A. What action is EPA taking? 

EPA is announcing the availability of 

final test guidelines under Series 850— 

Ecological Effects Test Guidelines, 

consisting of Groups B, C, D, and F: 

• Group B—Terrestrial Wildlife. 

• Group C—Terrestrial Beneficial 

Insects, Invertebrates, and Soil and 

Wastewater Microorganisms. 

• Group D—Terrestrial and Aquatic 

Plants, Cyanobacteria, and Terrestrial 

Soil Core Microcosm. 

• Group F—Field Test Data Reporting 

Guidelines. 

OCSPP, formerly the Office of 

Prevention, Pesticides and Toxic 

Substances (OPPTS), established a 

unified library of test guidelines for use 

in developing data for submission to 

EPA under TSCA, FFDCA, and/or 

FIFRA. Beginning in 1991, EPA initiated 

an effort to harmonize the test 

guidelines within OCSPP, as well as to 

harmonize the OCSPP test guidelines 

with those of the Organization for 

Economic Cooperation and 

Development (OECD). The process for 

developing and amending these test 

guidelines has included public 

participation and the extensive 

involvement of the scientific 

community, including peer review by 

the FIFRA Scientific Advisory Panel 

(SAP), the Scientific Advisory Board 

(SAB), and other expert scientific 

organizations. With this notice, EPA is 

announcing the availability of the final 

test guidelines OCSPP 850 Series, 

consisting of Groups B, C, D, and F 

dealing with ecological effects for use in 

testing chemical substances and 

developing data for submission to EPA. 

Test guidelines in this series were made 

available for public comment by a 

notice document published in the 

Federal Register issue of March 4, 1996 

(61 FR 8279) (FRL–4990–3). The peer 

review on May 29, 1996 by FIFRA SAP 

was announced in a meeting notice 

published in the Federal Register issue 

of May 1, 1996 (61 FR 19276) (FRL– 


srobinson on DSK4SPTVN1PROD with NOTICES
Federal Register / Vol. 77, No. 124 / Wednesday, June 27, 2012 / Notices 38283 

5366–3). The test guidelines were 

subsequently revised in response to 

FIFRA SAP and public comments. 

Based on comments from FIFRA SAP 

and from the public, the following 

changes were made in the final test 

guidelines: 

1. Group titles and organization 

changes. EPA is changing the title of 

Group D ‘‘Nontarget Plants Test 

Guidelines’’ to ‘‘Terrestrial and Aquatic 

Plants, Cyanobacteria, and Terrestrial 

Soil Core Microcosm Test Guidelines.’’ 

The term ‘‘nontarget,’’ which is not 

applicable to OPPT, is removed from the 

Group D title, broadening the scope to 

all test guidelines evaluating effects to 

plants. The following test guidelines 

involving plants are renumbered and 

moved to Group D: OCSPP 850.4500 

‘‘Algal Toxicity’’ (Public Draft OPPTS 

850.5400) and OCSPP 850.4900 

‘‘Terrestrial Soil-Core Microcosm Test’’ 

(Public Draft OPPTS 850.2450). 

EPA is changing the title of Group C 

‘‘Beneficial Insects and Invertebrates 

Test Guidelines’’ to ‘‘Terrestrial 

Beneficial Insects, Invertebrates, and 

Soil and Wastewater Microorganism 

Test Guidelines,’’ expanding the scope 

to include testing of microorganisms 

other than the aquatic algae. The 

following microorganism test guidelines 

are renumbered and moved to Group C: 

OCSPP 850.3200 ‘‘Soil Microbial 

Community Toxicity Test’’ (Public Draft 

OPPTS 850.5100) and OCSPP 850.3300 

‘‘Modified Activated Sludge, 

Respiration Inhibition Test’’ (Public 

Draft OPPTS 850.6800). 

EPA is moving the ‘‘Earthworm 

Subchronic Toxicity Test’’ test guideline 

from the Public Draft Group F 

‘‘Chemical Specific Test Guidelines’’ to 

Group C and renumbering it from 

OPPTS 850.6200 to OCSPP 850.3100. 

The earthworm is being added to Group 

C since it is a beneficial soil 

invertebrate. 

EPA is changing the Group G 

designation to Group F, and the test 

guideline contained within it (Public 

Draft OPPTS 850.7100) is renumbered 

OCSPP 850.6100. The title for Group E 

is removed as it no longer contains any 

test guidelines; however, Group E and 

its title are reserved. 

2. Title change for OCSPP 850.4000. 

EPA is changing the title of OCSPP 

850.4000 ‘‘Background—Nontarget Plant 

Testing’’ to ‘‘Background and Special 

Considerations: Tests with Terrestrial 

and Aquatic Plants, Cyanobacteria, and 

Terrestrial Soil-Core Microcosms.’’ The 

new title reflects the change in the 

Group D title. 

3. Background and special 

consideration test guideline addition for 

Group B and Group C and content 

revision of Group D. EPA is adding two 

background and special consideration 

test guidelines: OCSPP 850.2000 

‘‘Background and Special 

Considerations: Terrestrial Wildlife’’ 

and OCSPP 850.3000 ‘‘Background and 

Special Considerations: Terrestrial 

Beneficial Insects, Invertebrates, and 

Soil and Wastewater Microorganisms.’’ 

The addition of these test guidelines are 

in response to comments regarding 

harmonizing the organization of test 

guidelines and improving the 

consistency of terminology and 

guidance applicable across test 

guidelines in a group. These test 

guidelines provide general guidance on 

test methods, statistics, and data 

reporting and an overview of the use for 

OPPT and OPP. Such test guidelines 

already exist for Group A (OPPTS 

850.1000) and Group D (OCSPP 

850.4000). Information contained within 

the OCSPP 850.2000 and OCSPP 

850.3000 is based on information 

extracted from the test guidelines within 

their respective group and on general 

statistical methods applicable to toxicity 

testing. 

With the addition of test guidelines 

from other groups, OCSPP 850.4000 was 

updated to reflect general information 

applicable across test guidelines in 

Group D. This information was 

extracted from the existing test 

guidelines. Additionally, a description 

of the meaning of the terms ‘‘Tier I,’’ 

‘‘Tier II,’’ and ‘‘Tier III,’’ under TSCA in 

contrast to their definitions under 

FIFRA, was added. 

4. Title changes and merging and 

splitting of test guidelines—i. Removal 

of terms ‘‘Tiers I, II, and III’’ from test 

guideline titles and consolidation of 

resulting common test guidelines. The 

terms ‘‘Tier I,’’ ‘‘Tier II,’’ or ‘‘Tier III’’ 

used in these test guideline titles are not 

necessary and are misleading as they 

have different regulatory meanings 

under OPP and OPPT. These tests, 

though, are used by both programs. EPA 

is changing the OPPTS 850.4400 

‘‘Aquatic Plant Toxicity Test Using 

Lemna Spp., Tiers I and II’’ and OPPTS 

850.5400 (now OCSPP 850.4500) ‘‘Algal 

Toxicity, Tiers I and II’’ test guideline 

titles by removing ‘‘Tiers I and II.’’ 

EPA is also removing the terms ‘‘Tier 

I’’ and ‘‘Tier II’’ and then consolidating 

and harmonizing the ‘‘Tier I’’ test 

guidelines with their ‘‘Tier II’’ test 

guideline counterparts for the following 

test guidelines: The ‘‘Terrestrial Plant 

Toxicity, Tier I (Seedling Emergence)’’ 

and ‘‘Seedling Emergence, Tier II’’ test 

guidelines (Public Drafts OPPTS 

850.4100 and OPPTS 850.4225, 

respectively). These test guidelines were 

merged and harmonized into OCSPP 

850.4100 ‘‘Seedling Emergence and 

Seedling Growth.’’ The ‘‘Terrestrial 

Plant Toxicity, Tier I (Vegetative Vigor)’’ 

and ‘‘Vegetative Vigor, Tier II’’ test 

guidelines (Public Draft OPPTS 

850.4150 and OPPTS 850.4250, 

respectively) were merged and 

harmonized into OCSPP 850.4150 

‘‘Vegetative Vigor.’’ For these test 

guidelines, except for the number of 

treatment levels, ‘‘Tier I’’ test conditions 

(referred to as limit tests) are essentially 

the same as ‘‘Tier II’’ (definitive tests) 

test conditions. 

EPA is changing the title of OPPTS 

850.4450 ‘‘Aquatic Plants Field Study, 

Tier III’’ test guideline by removing the 

term, ‘‘Tier III.’’ 

EPA is also removing the term ‘‘Tier 

III’’ from the OPPTS 850.4300 

‘‘Terrestrial Plants Field Study, Tier III’’ 

test guideline. Public Draft OPPTS 

850.4025 ‘‘Target Area Phytotoxicity’’ 

was merged with Public Draft OPPTS 

850.4300 to create a single test 

guideline, OCSPP 850.4300 ‘‘Terrestrial 

Plants Field Study.’’ The target area test 

guideline covers a special case of a 

terrestrial plant field study for OPP, 

where the study area is the area 

intentionally treated with a pesticide 

when label use directions are followed. 

The OCSPP 850.4300 ‘‘Terrestrial Plants 

Field Study’’ provides flexibility to 

cover this special case for OPP, if 

needed. 

ii. Division of the Algal Toxicity Test 

into two separate guidelines. EPA split 

the Public Draft OPPTS 850.5400 ‘‘Algal 

Toxicity, Tiers I and II’’ test guideline 

into two test guidelines: OCSPP 

850.4500 ‘‘Algal Toxicity’’ and OCSPP 

850.4550 ‘‘Cyanobacteria (Anabaena 

flos-aquae) Toxicity’’ (in addition to 

removing ‘‘Tiers I and II’’). This division 

of the unicellular species into two 

different test guidelines provides a 

clearer differentiation between 

methodological approaches prescribed 

for testing cyanobacteria and those for 

testing the unicellular algae. 

Additionally, this division addresses the 

reclassification of blue-green algae as 

cyanobacteria. 

5. Standardization of test guideline 

organization. The FIFRA SAP 

recommended that the ecological effects 

test guidelines include the same 

organizational format and that the tables 

summarizing test conditions for 

appropriate test guidelines contain 

consistent concepts across test 

guidelines. As a result of these 

suggestions, information was moved 

within the test guidelines, but the 

information remained the same. Tables 

summarizing test conditions and test 

validity elements were added to test 

guidelines in which species specific or 


srobinson on DSK4SPTVN1PROD with NOTICES
38284 Federal Register / Vol. 77, No. 124 / Wednesday, June 27, 2012 / Notices 

laboratory measurements were defined. 

In all test guidelines where a calculated 

response measure (e.g., average specific 

growth rate) was derived from direct 

response measures (e.g., weight), 

equations were provided. 

6. Highlights of technical changes—i. 

Addition of a limit test option. Public 

comments indicated that a limit test 

could be an option to a definitive test 

in additional test guidelines. A limit test 

provides an opportunity to reduce the 

number of animals to be tested and/or 

resources. Test guidelines where a limit 

test is appropriate and a limit test 

option was added include the following: 

OCSPP 850.2200 ‘‘Avian Dietary 

Toxicity Test;’’ OCSPP 850.2400 ‘‘Wild 

Mammal Toxicity Test;’’ OCSPP 

850.3100 ‘‘Earthworm Subchronic 

Toxicity Test;’’ OCSPP 850.3300 

‘‘Modified Activated Sludge, 

Respiration Inhibition Test;’’ OCSPP 

850.4230 ‘‘Early Seedling Growth 

Toxicity Test;’’ and OCSPP 850.4600 

‘‘Rhizobium-Legume Toxicity.’’ 

Although a limit test option is available 

for OCSPP 850.2100, OCSPP 850.2200, 

and OCSPP 850.2400, language was 

added that if sublethal effects are 

observed at the limit dose, a definitive 

test should be conducted. 

ii. Modification of limit dosage or 

concentration ‘‘cut-off’’ values. The 

limit dosage or concentration values for 

tests for pesticides were originally set at 

values seen in the literature as ‘‘cut off’’ 

values. It was believed that few, if any, 

pesticides would be applied at a label 

rate that would result in residues equal 

to or greater than these values. Based on 

current exposure models used within 

the Office of Pesticide Programs (OPP), 

though, there are cases where estimated 

environmental residue values are higher 

than limit values provided in the public 

drafts, and there are also cases where 

actual or expected environmental 

exposure levels may be higher than the 

limit values for industrial chemicals. To 

address these case-by-case occurrences, 

language was added saying that the 

limit value should be adjusted upward 

if environmental exposure 

concentrations are expected to be higher 

than the limit value. In addition, 

guidance on how to calculate a pesticide 

estimated environmental concentration 

for comparison to a typical limit value 

was included in each test guideline with 

a limit test option. 

iii. Group B test guidelines. In OCSPP 

850.2100 ‘‘Avian Acute Oral Toxicity 

Test,’’ passerine species and alternative 

species were added as test species in 

response to FIFRA SAP comments for 

additional alternative test species and 

the new passerine 40 CFR part 158 data 

requirement published in the Federal 

Register issue of October 26, 2007 (72 

FR 60934–60988) (FRL–8106–5). 

Furthermore, the option of testing 

additional sex and age groups 

(including breeding females) on a caseby-case basis, as well as confirmation of 

dosing solutions, were added to address 

comments. OCSPP 850.2200 ‘‘Avian 

Dietary Toxicity’’ was modified to 

specify that young birds cannot survive 

5 days without feeding. Additionally, 

when delayed effects are observed or 

expected, the guidance extending the 

observation period recommends testing 

for at least 14 days but continuing until 

overt evidence of toxicity has subsided. 

There were also issues raised with the 

cage sizes provided in OCSPP 850.2300 

‘‘Avian Reproduction Test.’’ In response 

to these comments, the specific cage 

sizes provided in OCSPP 850.2300 were 

removed and replaced with a 

recommendation to follow current best 

practices for the care and testing of 

laboratory animals, as recommended 

cage sizes for avian species for use in 

reproductive tests are evolving. The 

health and presence/absence of signs of 

stress in control animals are used to 

help evaluate housing and handling 

conditions. Additionally, language was 

added to increase the minimum number 

of replicate pens per treatment to 16, 

and the measurement endpoint of 

hatchling body weight was added. 

Furthermore, the initial test subject age 

was reduced to as low as 16 weeks to 

address comments on problems of 

starting with older test subjects and 

impacts on acclimation, holding, and 

initial photoperiod during the 

reproduction phase. 

iv. Group C test guidelines. In OCSPP 

850.3020 ‘‘Honey Bee Acute Contact 

Toxicity’’ and OCSPP 850.3030 ‘‘Honey 

Bee Toxicity of Residues on Foliage,’’ 

the age of test bees was harmonized 

with that in OECD 214 ‘‘Honeybees, 

Acute Contact Toxicity Test’’ and with 

FIFRA SAP comments. A method for 

immobilizing bees using cold 

temperature was included and the 

wording on the source of bees was 

changed to an ‘‘apparently disease-free 

colony’’ in response to comments on 

collection techniques and source of 

bees. In addition, language regarding 

measurements of residue concentrations 

on the foliage was added. 

v. Group D test guidelines. In 

conducting ecological risk assessments, 

both hypothesis-based endpoints (No 

Observed Effect Concentration/Lowest 

Observed Effect Concentration (NOEC/ 

LOEC)) and regression-based endpoints 

(e.g., inhibition concentration IC25 or 

IC50) are recommended in OCSPP 

850.4100 ‘‘Seedling Emergence and 

Seedling Growth,’’ OCSPP 850.4150 

‘‘Vegetative Vigor,’’ OCSPP 850.4400 

‘‘Aquatic Plant Toxicity Test Using 

Lemna spp.,’’ OCSPP 850.4500 ‘‘Algal 

Toxicity,’’ and OCSPP 850.4550 

‘‘Cyanobacteria (Anabaena flos-aquae) 

Toxicity.’’ Within these test guidelines, 

text was modified to clarify both 

objectives and test acceptability in terms 

of both definitive and limit tests. A 

number of modifications to OCSPP 

850.4400 were made to harmonize the 

test guideline with OECD 221 ‘‘Lemna 

sp Growth Inhibition.’’ A change in the 

period of testing from 14 days to 7 days 

was made in alignment with the OECD 

221 guideline based on bridging data 

between 7-day and 14-day results. An 

evaluation of in-house toxicity data on 

Lemna gibba demonstrated no 

significant difference between the 

inhibition concentration endpoint 

values at 7 days versus 14 days. 

The minimum number of replicates 

has been increased to 4 for OCSPP 

850.4100 ‘‘Seedling Emergence and 

Seedling Growth,’’ OCSPP 850.4150 

‘‘Vegetative Vigor,’’ OCSPP 850.4400 

‘‘Aquatic Plant Toxicity Testing Using 

Lemna spp.,’’ OCSPP 850.4500 ‘‘Algal 

Toxicity,’’ and OCSPP 850.4550 

‘‘Cyanobacteria (Anabaena flos-aquae) 

Toxicity’’ to reflect the objective of these 

tests within OPP in which a hypothesisbased no observable adverse effect 

concentration (NOAEC) in addition to 

the regression-based ICX is calculated. 

The NOAEC is used in endangered and 

threatened species assessments and 

there are cases where nonparametric 

tests, which require a minimum of 4 

replicates, are needed to evaluate the 

results. Additional modifications to 

OCSPP 850.4550 were made to reflect 

FIFRA SAP recommendations of not 

continuously shaking test vessels during 

the test and using sonification only to 

facilitate counting. 

B. How were these test guidelines 

developed? 

OCSPP has developed a unified 

library of test guidelines, which are 

used in the testing of pesticides and 

toxic substances, and in the 

development of test data to meet the 

data requirements of the Agency or for 

voluntary testing purposes. Test 

guidelines are documents that specify 

methods that EPA recommends for 

generating data to support the 

registration of a pesticide, for setting of 

a tolerance or tolerance exemption for 

pesticide residues, or for the 

decisionmaking process for an 

industrial chemical. These test data are 

used by the Agency to perform risk 

assessments and make regulatory 

decisions. Studies conducted according 

to these test guidelines may be required 


srobinson on DSK4SPTVN1PROD with NOTICES
Federal Register / Vol. 77, No. 124 / Wednesday, June 27, 2012 / Notices 38285 

under FIFRA (7 U.S.C. 136) for pesticide 

registration, pursuant to 40 CFR part 

158. Test guideline studies may also be 

useful for satisfying FIFRA data 

requirements either in data call-ins 

issued pursuant to FIFRA section 

3(c)(2)(B) or as needed to satisfy data 

requirements appropriate for specific 

pesticide registration applications, or for 

satisfying data requirements to 

demonstrate the safety of a tolerance or 

tolerance exemption under FFDCA 

section 408 (21 U.S.C. 346a). 

Test guidelines used in regulatory 

actions as the basis for test standards 

under TSCA (15 U.S.C. 2601) are 

typically promulgated in 40 CFR part 

799. They may also be written into 

specific TSCA rules such as TSCA 

section 4 test rules or consent orders or 

they may be used as recommended test 

guidelines as part of voluntary testing. 

Note that where data will be required 

under a TSCA rule, such as a test rule 

under TSCA section 4, a TSCA-specific 

version of the applicable test guideline 

may be promulgated as a rule. Examples 

of specific chemical test rules and 

consent orders may be found in 40 CFR 

part 799, subparts B and C. 

The availability of public draft test 

guidelines for public comment was 

announced in a March 4, 1996 Federal 

Register notice. The public draft test 

guidelines were placed in the EPA 

Docket for public access. These public 

draft test guidelines were also submitted 

by EPA to FIFRA SAP on May 29, 1996, 

for peer review and was announced in 

a May 1, 1996 Federal Register notice. 

These final test guidelines incorporate 

changes recommended by FIFRA SAP 

and other changes resulting from the 

public comments received in response 

to the 1996 public draft test guidelines. 

The majority of comments and changes 

dealt with the organizational structure 

of the test guideline groups, consistency 

of organization and format across the 

ecological effects guidelines, addition of 

tables summarizing test conditions, 

addition of tables summarizing test 

validity elements, consistency in use of 

terminology, and updating of references. 

The reporting section of each test 

guideline now provides a list of study 

specific information to include in a 

study report based on study reporting 

requirements specified in 40 CFR 

160.185 for FIFRA and 40 CFR 792.185 

for TSCA. 

List of Subjects 

Environmental protection, Chemical 

testing, Test guideline. 

Dated: June 19, 2012. 

James Jones, 

Acting Assistant Administrator, Office of 

Chemical Safety and Pollution Prevention. 

[FR Doc. 2012–15540 Filed 6–26–12; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[EPA–HQ–OPP–2012–0101; FRL–9348–5] 

Pesticide Products; Registration 

Applications 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: This notice announces receipt 

of applications to register pesticide 

products containing new active 

ingredients not included in any 

currently registered products pursuant 

to the provisions of section 3(c)(4) of the 

Federal Insecticide, Fungicide, and 

Rodenticide Act (FIFRA), as amended. 

DATES: Comments must be received on 

or before July 27, 2012. 

ADDRESSES: Submit your comments, 

identified by docket identification (ID) 

number EPA–HQ–OPP–2012–0101; 

FRL–9348–5, by one of the following 

methods: 

• Federal eRulemaking Portal: http:// 

www.regulations.gov. Follow the online 

instructions for submitting comments. 

Do not submit electronically any 

information you consider to be 

Confidential Business Information (CBI) 

or other information whose disclosure is 

restricted by statute. 

• Mail: OPP Docket, Environmental 

Protection Agency Docket Center (EPA/ 

DC), Mail Code: 28221T, 1200 

Pennsylvania Ave. NW., Washington, 

DC 20460–0001. 

• Hand Delivery: To make special 

arrangements for hand delivery or 

delivery of boxed information, please 

follow the instructions at http:// 

www.epa.gov/dockets/contacts.htm. 

Additional instructions on commenting 

or visiting the docket, along with more 

information about dockets generally, is 

available at http://www.epa.gov/ 

dockets. 

FOR FURTHER INFORMATION CONTACT: A 

contact person is listed at the end of 

each registration application summary 

and may be contacted by telephone, 

email, or mail. Mail correspondence to 

the Biopesticides and Pollution 

Prevention Division (7511P) or the 

Registration Division (7505P), Office of 

Pesticide Programs, Environmental 

Protection Agency, 1200 Pennsylvania 

Ave. NW., Washington, DC 20460–0001. 

As part of the mailing address, include 

the contact person’s name, division, and 

mail code. 

SUPPLEMENTARY INFORMATION: 

I. General Information 

A. Does this action apply to me? 

You may be potentially affected by 

this action if you are an agricultural 

producer, food manufacturer, or 

pesticide manufacturer. Potentially 

affected entities may include, but are 

not limited to: 

• Crop production (NAICS code 111). 

• Animal production (NAICS code 

112). 

• Food manufacturing (NAICS code 

311). 

• Pesticide manufacturing (NAICS 

code 32532). 

This listing is not intended to be 

exhaustive, but rather provides a guide 

for readers regarding entities likely to be 

affected by this action. Other types of 

entities not listed in this unit could also 

be affected. The North American 

Industrial Classification System 

(NAICS) codes have been provided to 

assist you and others in determining 

whether this action might apply to 

certain entities. If you have any 

questions regarding the applicability of 

this action to a particular entity, consult 

the person listed under FOR FURTHER

INFORMATION CONTACT. 

B. What should I consider as I prepare 

my comments for EPA? 

1. Submitting CBI. Do not submit this 

information to EPA through 

regulations.gov or email. Clearly mark 

the part or all of the information that 

you claim to be CBI. For CBI 

information in a disk or CD–ROM that 

you mail to EPA, mark the outside of the 

disk or CD–ROM as CBI and then 

identify electronically within the disk or 

CD–ROM the specific information that 

is claimed as CBI. In addition to one 

complete version of the comment that 

includes information claimed as CBI, a 

copy of the comment that does not 

contain the information claimed as CBI 

must be submitted for inclusion in the 

public docket. Information so marked 

will not be disclosed except in 

accordance with procedures set forth in 

40 CFR part 2. 

2. Tips for preparing your comments. 

When submitting comments, remember 

to: 

i. Identify the document by docket ID 

number and other identifying 

information (subject heading, Federal 

Register date and page number). If you 

are commenting in a docket that 

addresses multiple products, please 

indicate to which file symbol(s) your 

comment applies. 


srobinson on DSK4SPTVN1PROD with NOTICES