UNITED STATES


SECURITIES AND EXCHANGE COMMISSION


Washington, D.C. 20549





FORM 10-Q





[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934





For the quarterly period ended March 31, 2010





OR





[   ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934





For the transition period from ________ to ________.





Commission File Number: 000-50484





Marshall Edwards, Inc.


(Exact name of registrant as specified in its charter)





DELAWARE
51-0407811(State or other jurisdiction of
(I.R.S. Employer Identification No.)incorporation or organization)





140 Wicks Road, North Ryde, NSW, 2113 Australia


(Address of principal executive offices) (Zip Code)





(011) 61 2 8877- 6196


Registrant’s telephone number, including area code:











Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes   x   No   o





Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes    o No  o





Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See definition of “large accelerated filer,” “accelerated filer,” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.


Large accelerated filer      o
Non-accelerated filer                            xAccelerated filero
Smaller reporting entity                          o





Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).Yes   oNo   x





As of April 30, 2010 the number of shares outstanding of the issuer’s common stock, $0.00000002 par value, was 7,346,323.

















MARSHALL EDWARDS, INC.





INDEX


PART I
FINANCIAL INFORMATION
PageItem 1:
Financial Statements (Unaudited)Consolidated Balance Sheets as of March 31, 2010 and June 30, 2009
3Consolidated Statements of Operations for the three months and nine months ended March 31, 2010 and 2009 and for the period from December 1, 2000 (inception) through March 31, 2010
4Consolidated Statements of Cash Flows for the nine months ended March 31, 2010 and 2009 and for the period from December 1, 2000 (inception) through March 31, 2010
5Consolidated Statement of Stockholders’ Equity
6Notes to Consolidated Financial Statements
7Item 2:
Management’s Discussion and Analysis of Financial Condition and Results of Operation
19Item 3:
Quantitative and Qualitative Disclosures about Market Risk
28Item 4T:
Controls and Procedures
29PART II
OTHER INFORMATIONItem 6:
Exhibits
31SIGNATURES
32








2


PART I  FINANCIAL INFORMATION


Item 1: Financial Statements





MARSHALL EDWARDS, INC.


(A Development Stage Company)


CONSOLIDATED BALANCE SHEETS


(In thousands, except share and per share data)





March 31,


June 30,2010


2009(unaudited)


(Note 1)ASSETSCurrent assetsCash and cash equivalents

$
11,341


$
19,067Prepaid expenses and other current assets


110



289Total current assets


11,451



19,356Total assets

$
11,451


$
19,356LIABILITIES AND STOCKHOLDERS' EQUITYCurrent liabilitiesAccounts payable

$
760


$
736Accrued expenses


1,011



3,186Amount due to related company


521



221Total current liabilities


2,292



4,143Stockholders' equity:Preferred stock, $0.01 par value, authorized 100,000 shares,none outstanding


-



-Common stock, $ 0.00000002 par value, 113,000,000 authorizedshares; shares issued and outstanding: 7,346,323 atMarch 31, 2010 and 7,346,323 at June 30, 2009


-



-Additional paid-in capital


78,124



78,124Deficit accumulated during development stage


(68,965
)


(62,911
)Total stockholders' equity


9,159



15,213Total liabilities and stockholders' equity

$
11,451


$
19,356





See accompanying notes to the consolidated financial statements.








3


MARSHALL EDWARDS, INC.


(A Development Stage Company)


CONSOLIDATED STATEMENTS OF OPERATIONS


(In thousands, except share and per share data)


(Unaudited)






Three Months Ended

March 31,


Nine Months Ended

March 31,


Period from December 1, 2000 (Inception) through

March 31,2010


2009


2010


2009


2010Revenues:Interest and other income

$
19


$
29


$
68


$
201


$
2,714Total revenues


19



29



68



201



2,714Operating expenses:Research and development


(1,559
)


(1,545
)


(3,053
)


(4,988
)


(36,096
)License fees


-



-



(1,500
)


-



(21,500
)Selling, general and administrative


(673
)


(388
)


(1,569
)


(967
)


(14,076
)Total operating expenses


(2,232
)


(1,933
)


(6,122
)


(5,955
)


(71,672
)Loss from operations


(2,213
)


(1,904
)


(6,054
)


(5,754
)


(68,958
)Income tax expense


-



-



-



(1
)


(7
)Net loss arising during development stage

$
(2,213
)

$
(1,904
)

$
(6,054
)

$
(5,755
)

$
(68,965
)Net loss per common share:Basic and diluted

$
(0.30
)

$
(0.26
)

$
(0.82
)

$
(0.79
)Weighted average number of common shares outstanding


7,346,323



7,346,323



7,346,323



7,294,186











See accompanying notes to the consolidated financial statements.







4


MARSHALL EDWARDS, INC.


(A Development Stage Company)


CONSOLIDATED STATEMENTS OF CASH FLOWS


(In thousands)


(Unaudited)








Nine Months Ended

March 31,


Period from December 1, 2000 (Inception) through

March 31,2010


2009


2010Operating activitiesNet loss arising during development stage

$
(6,054
)

$
(5,755
)

$
(68,965
)Adjustments to reconcile net loss to net cash(used in) provided by operating activities:Share based payments


-



90



1,732Changes in operating assets and liabilities:Prepaid expenses and other current assets


179



(29
)


(110
)Accounts payable


24



(18
)


760Accrued expenses


(2,175
)


(522
)


1,011Amounts due to related company


300



(235
)


521Net cash used in operating activities


(7,726
)


(6,469
)


(65,051
)Financing activitiesNet proceeds from issuance of  common stock


-



9,878



76,392Net cash provided by financing activities


-



9,878



76,392Net (decrease)/increase in cash and cash equivalents


(7,726
)


3,409



11,341Cash and cash equivalents at beginning of period


19,067



19,743



-Cash and cash equivalents at end of period

$
11,341


$
23,152


$
11,341




















See accompanying notes to the consolidated financial statements.







5


MARSHALL EDWARDS, INC.


(A Development Stage Company)


CONSOLIDATED STATEMENT OF STOCKHOLDERS’ EQUITY


(In thousands, except share data)


(Unaudited)





Common Stock


Additional paid in capital


Deficit accumulated during development

stage


Total(shares)Balance at June 30, 2009


7,346,323


$
78,124


$
(62,911
)

$
15,213Net loss arising during development stage


-



-



(6,054
)


(6,054
)Comprehensive Loss














(6,054
)Balance at March 31, 2010


7,346,323


$
78,124


$
(68,965
)

$
9,159














See accompanying notes to the consolidated financial statements.








6


MARSHALL EDWARDS, INC.


(A Development Stage Company)


NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


(Unaudited)








1. Basis of Presentation and Summary of Significant Accounting Policies





Marshall Edwards, Inc. (“MEI”) including its wholly-owned subsidiary Marshall Edwards Pty Ltd (“MEPL”) (together, the “Group” or the “Company”) is a development stage company incorporated in December 2000 as a wholly-owned subsidiary of Novogen Limited (“Novogen”).  As of the date of this Quarterly Report, Novogen owns approximately 71.3% of the outstanding shares of the Company’s common stock.





The Company’s financial statements have been prepared in accordance with U.S. generally accepted accounting principles or “GAAP” for the interim financial information and with the instructions to Form 10-Q and Article 10 of Regulation S-X of the Securities Exchange Act of 1934, as amended. Accordingly they do not include all of the information and footnotes required by GAAP for complete financial statements. The Company believes all adjustments (consisting only of normal recurring adjustments) considered necessary for a fair presentation have been included herein. Operating results for the three months and nine months ended March 31, 2010 are not necessarily indicative of the results that may be expected for the year ending June 30, 2010 or any other future period. The balance sheet at June 30, 2009 has been derived from the audited financial statements at that date. You should read these financial statements and notes in conjunction with the audited financial statements for the year ended June 30, 2009 which are included in the Company’s Annual Report on Form 10-K filed with the Securities and Exchange Commission.





Principles of Consolidation





The consolidated financial statements include the accounts of MEI and its wholly-owned subsidiary MEPL. Significant intercompany accounts and transactions have been eliminated on consolidation.





Estimates





The preparation of the consolidated financial statements, in conformity with accounting principles generally accepted in the U.S., requires management to make estimates and assumptions that affect the amounts reported in the financial statements and the accompanying notes. Actual results could differ from those estimates.





Revenue Recognition





Interest





The only revenue earned to date is interest on cash balances, which is recognized on an accruals basis.





7


Cash and Cash Equivalents





Cash on hand and in banks and short-term deposits is stated at its nominal value. The Company considers all highly liquid investments, with a maturity of three months or less when purchased, to be cash equivalents. Highly liquid investments with stated maturities of greater than three months are classified as short-term investments. The Company’s cash, held in the U.S., is deposited in financial institutions that are FDIC insured. These deposits are in excess of the FDIC insurance limits. The Company also holds cash with Australian financial institutions. Cash deposits held in Australian banks are guaranteed by the Australian Government up to a maximum amount of A$1 million per account.





Income Taxes





Income taxes have been provided for using the liability method. Under this method, deferred tax assets and liabilities are recognized and measured using enacted tax rates in effect for the year in which the differences are expected to be recognized. Valuation allowances are established against the recorded deferred income tax assets to the extent that management believes that it is more likely than not that a portion of the deferred income tax assets are not realizable. There is a full valuation allowance against net deferred tax assets.





The Company accounts for any uncertain tax position by using a two step approach. Step one, recognition, requires a company to determine if the weight of available evidence indicates that a tax position is more likely than not to be sustained upon audit, including resolution of related appeals or litigation processes, if any. Step two, measurement, is based on the largest amount of benefit, which is more likely than not to be realized upon ultimate settlement. Additionally, tax positions for which the timing of the ultimate resolution is uncertain are recognized as long term liabilities.





The Company’s major tax jurisdictions are the U.S. and Australia and its tax years since inception remain subject to examination by the appropriate governmental agencies in those jurisdictions due to its tax loss position.





Fair Value of Financial Instruments





The carrying amounts of the Company’s financial instruments, including cash and cash equivalents and accounts payable, approximate fair value. Fair value has been determined based on the fair value of identical investments in active markets. All cash and cash equivalents are classified as level 1 as defined by the fair value hierarchy.





Foreign Currency Translation





The financial statements of MEPL have been translated into U.S. dollars. Assets and liabilities are translated into U.S. dollars using the exchange rates in effect at the balance sheet date. Income statement amounts have been translated using the average exchange rate for the periods. Realized gains and losses from foreign currency transactions are reflected in the consolidated statements of operations.





Translation of MEPL’s financial statements into U.S. dollars does not have a material impact on the Company’s financial position.





8


Research and Development Expenses





Research and development expenses relate primarily to the cost of conducting human clinical and pre-clinical research of the licensed cancer compounds. Research and development costs are charged to earnings in the period incurred.





Clinical development costs are a significant component of research and development expenses. Estimates have been used in determining the expense liability under certain clinical trial contracts where services have been performed but not yet invoiced. The actual costs of those services could differ in amount and timing from the estimates used in completing the financial statements.





License Fees





Costs incurred related to the acquisition or licensing of products that have not yet received regulatory approval to be marketed, or that are not commercially viable and ready for use or have no alternative future use, are charged to earnings in the period incurred.





The license agreements with Novogen may be cancelled without penalty by MEPL by giving three months’ notice. Therefore license fees due under these license agreements are recognised as an expense when the milestone event occurs.





Stock-Based Compensation





The Company’s 2008 Stock Omnibus Equity Compensation Plan provides for the grant of options to the Company’s directors, employees, employees of the Company’s affiliates and certain of the Company’s contractors and consultants.





The Company recognizes the cost of goods acquired or the expense for services received in a share-based payment transaction when it obtains the goods or as services are received. The Company recognizes a corresponding increase in equity or a liability depending on the classification of the share-based instrument granted.





Basic and Diluted Loss Per Share





In computing basic earnings or loss per share, the dilutive effect of stock options and warrants are excluded, whereas for diluted earnings or loss per share they are included unless the effect is anti-dilutive.





Stockholders’ Equity





Ordinary share capital is recognized at the fair value of the consideration received by the Company. Any transaction costs arising on the issue of shares are recognized directly in equity as a reduction in the share proceeds received.





9


Deferred Offering Costs





Where costs associated with a capital raising have been incurred at balance date and it is probable that the capital raising will be successfully completed after balance date, such costs are deferred and offset against the proceeds subsequently received from the capital raising.





2. Loss Per Share





The following table sets forth the computation of basic and diluted net loss per common share:





Three Months Ended

March 31,


Nine Months Ended

March 31,2010


2009


2010


2009(In Thousands, except share and per share data)


(In Thousands, except share and per share data)NumeratorNet loss arising during development stage


(2,213
)


(1,904
)


(6,054
)


(5,755
)Numerator for diluted earnings per share

$
(2,213
)

$
(1,904
)

$
(6,054
)

$
(5,755
)DenominatorDenominator for basic earnings per share:Weighted average number of shares used in computing net loss per share, basic and diluted


7,346,323



7,346,323



7,346,323



7,294,186Dilutive potential common shares


7,346,323



7,346,323



7,346,323



7,294,186Basic and diluted earnings per share

$
(0.30
)

$
(0.26
)

$
(0.82
)

$
(0.79
)


During the period presented, the Company had warrants and stock options outstanding that could potentially dilute basic earnings per share in the future, but were excluded from the computation of diluted net loss per share as the effect would have been anti-dilutive. Since the Company has a loss for all periods presented, diluted and basic earnings per share are the same. The outstanding warrants and stock options consist of the following potential common shares:





As at March 31,2010
2009(Number of shares)Warrants exercisable prior to July 11, 2010 at an exercise price of $43.50
281,525
281,525Warrants exercisable prior to August 6, 2012 at an exercise price of $36.00
218,559
218,559Warrants exercisable prior to August 6, 2012 at an exercise price of $30.00
24,836
24,836Warrants exercisable prior to July 30, 2013 at an exercise price of $21.70
4,608
4,608Stock options exercisable prior to January 28, 2014 at an exercise price of $6.30
5,000
5,000Common shares issuable upon exercise of outstanding warrants and stock options
534,528
534,528







10


3. Expenditure Commitments





At March 31, 2010, the Company had contractual obligations for the conduct of clinical trials, pre-clinical research and development and manufacturing process development of approximately $821,000. Of the expenditure commitments, clinical trial amounts are based on the assumption that all patients enrolled in clinical trials will complete the maximum number of allowed treatment cycles. The amounts, assuming all treatment cycles are completed, are expected to be incurred as follows:





(In thousands)




Payment due by periodContractual Obligations

Total


less than 1 Year


1 - 3 Years


3 - 5 Years


More than 5 YearsPurchase Obligations

$
821


$
662


$
60


$
99


$
-Total

$
821


$
662


$
60


$
99


$
-





No amounts have been included for future payments to Novogen which may arise in connection with the Phenoxodiol License Agreement, the License Agreement for Triphendiol and NV-143, the License Agreement for NV-128, the Services Agreement or the Manufacturing License and Supply Agreement as future payments under the terms of the agreements are subject to termination provisions. The terms of the agreements, including future payments, are detailed in Note 5 “Related Party Transactions.”





The Company is not currently a party to any material legal proceedings.





The Company’s certificate of incorporation provides that it will indemnify Novogen in connection with certain actions brought against Novogen by any of the Company’s stockholders or any other person.





Pursuant to the terms of a Guarantee and Indemnity Agreement, the Company has guaranteed the payment and performance of the obligations of MEPL to Novogen and its subsidiaries, Novogen Laboratories Pty Limited and Novogen Research Pty Limited, under the Phenoxodiol License Agreement, the Manufacturing License and Supply Agreement and the Services Agreement. Novogen has guaranteed the performance of the obligations of Novogen Research Pty Limited under the Phenoxodiol License Agreement and the obligations of Novogen Laboratories Pty Limited under the Manufacturing License and Supply Agreement to MEPL. Each of the Company and Novogen’s obligations in the Guarantee and Indemnity Agreement are absolute, unconditional and irrevocable.





11


4. Segment Information





The Company’s focus is the clinical development and commercialization of its licensed cancer compounds. The business contains two major segments based on geographic location.





Three Months Ended

March 31, 2010


Three Months Ended

March 31, 2009(In Thousands)USA


Australia


USA


AustraliaLoss from operations

$
(285
)

$
(1,928
)

$
(103
)

$
(1,801
)Segment assets


8,653



2,798



16,204



7,102Nine Months Ended

March 31, 2010


Nine Months Ended

March 31, 2009(In Thousands)USA


Australia


USA


AustraliaLoss from operations

$
(437
)

$
(5,617
)

$
(465
)

$
(5,290
)


5. Related Party Transactions





License Agreement for Phenoxodiol, as amended





In September 2003, the Company entered into a license agreement pursuant to which Novogen granted to MEPL a worldwide non-transferable license under its patents and patent applications and in its know-how to conduct clinical trials and commercialize and distribute phenoxodiol products (the “Phenoxodiol License Agreement”). The Phenoxodiol License Agreement covers uses of phenoxodiol in the field of prevention, treatment or cure of cancer in humans, delivered in all forms except topical applications. The license is exclusive until the expiration or lapsing of the last relevant Novogen patents or patent applications in the world and thereafter is non-exclusive. MEPL may terminate the Phenoxodiol License Agreement by giving three months’ notice to Novogen. MEPL paid $5,000,000 to Novogen in February 2004 which was the first lump sum license fee payment due under the terms of the Phenoxodiol License Agreement. Also, MEPL paid $2,000,000 to Novogen in January 2005 and $4,000,000 in January 2006 which were the annual milestone license fee payments due under the Phenoxodiol License Agreement. The Company paid a second lump sum license fee of $5,000,000 to Novogen in July 2006 following the raising of funds in a private placement or PIPE. This license fee was due on the later of November 1, 2003 or such later date when the cumulative total of all funds received from debt or equity issuances and revenue received from commercialization (income other than sales) and sales of phenoxodiol products exceeded $50,000,000. Following the PIPE capital raising which closed on July 11, 2006, the funds received from equity issuances exceeded $50,000,000 which triggered this license fee payment. Future amounts payable to Novogen under terms of the Phenoxodiol License Agreement are as follows:





1. Until the expiration of the exclusivity period of the license, MEPL must pay Novogen 2.5% of all net sales and 25% of commercialization income. After the exclusivity period of the license, 1.5% of net sales must be paid to Novogen. The preconditions to such payments have not yet occurred.





12


The “Exclusivity Period” ends on the later of:





(a)
the date of expiration or lapsing of the last patent right in the patents and patent applications set out in the Phenoxodiol License Agreement with Novogen; or





(b)
the date of expiration or lapsing of the last licensed patent right which MEPL would, but for the license granted in the Phenoxodiol License Agreement, infringe in any country in the geographical territory covered by the Phenoxodiol License Agreement by doing in that country any of the things set out in the Phenoxodiol License Agreement.





2. In addition to the amounts above, the License Agreement for Phenoxodiol was amended in June 2006 and April 2007 to provide that upon the earliest receipt (the “Approval Date”) by MEPL of the first:





(i)
approval by the U.S. Food and Drug Administration (the “FDA”) of a New Drug Application (“NDA”) for phenoxodiol;


(ii)
approval or authorization of any kind to market phenoxodiol in the United States; or


(iii)
approval or authorization of any kind by a government agency in any other country to market phenoxodiol,





MEPL will be required to pay Novogen Research Pty Limited $8,000,000, together with interest on such amount from (and including) December 31, 2006 to (but excluding) the Approval Date. Thereafter, MEPL will be required to make license milestone fee payments of $8,000,000 to Novogen Research Pty Limited on December 31 of the year of the Approval Date and on December 31 of each year thereafter during the exclusivity period under the Phenoxodiol License Agreement.





No license fees have been accrued in respect of phenoxodiol at March 31, 2010.





License Agreement for Triphendiol and NV-143





In May 2006, the Company entered into a second license agreement with Novogen for two oncology compounds, triphendiol and NV-143 (the “License Agreement for Triphendiol and NV-143”). Triphendiol is being developed initially in oral form for the treatment of pancreatic and bile duct cancer and has completed initial Phase I(a) human testing. NV-143 is targeted for the treatment of melanoma, also in oral dose form, and is in the pre-clinical stage. The License Agreement for Triphendiol and NV-143 is an agreement under which Novogen’s subsidiary, Novogen Research Pty Limited, grants to MEPL a worldwide non-transferable license under its patents and patent applications and in its know-how to conduct clinical trials and commercialize and distribute triphendiol and NV-143 products. The License Agreement for Triphendiol and NV-143 covers uses of triphendiol and NV-143 in the field of prevention, treatment or cure of cancer in humans delivered in all forms except topical applications. The license is exclusive until the expiration or lapsing of the last relevant Novogen patents or patent applications in the world and thereafter is non-exclusive. MEPL may terminate the agreement by giving three months’ notice to Novogen. The Company is required to make payments under the terms of the License Agreement for Triphendiol and NV-143 with Novogen as follows:





13


1.     A lump sum license fee of $1,000,000 is payable to Novogen on the commencement date of the license in consideration of the license granted. This initial lump sum license fee was paid to Novogen in May 2006.





2.     In further consideration of the license granted, MEPL must pay to Novogen the following milestone license fees upon the occurrence of the corresponding milestone as set forth below;





a)     the first license product containing triphendiol to reach a milestone as set forth below; and


b)     the first licensed product containing NV-143 to reach a milestone as set forth below.


The milestone license fees are:


i)
$1,000,000 on the date an Investigation New Drug Application (“IND”) for the licensed product goes into effect or the equivalent approval of a government agency is obtained in another country. If this event does not occur before March 31, 2008 then this amount will be due on this date. The amount of $1,000,000 was paid to Novogen on March 31, 2008 under the terms of this agreement;


ii)
$2,000,000 on the date of enrollment of the first clinical trial subject in a Phase II clinical trial of the licensed product. If this event does not occur before June 30, 2009, then this amount will be due on this date. The amount of $2,000,000 was paid to Novogen on June 30, 2009 under the terms of this agreement;


iii)
$3,000,000 on the date of enrollment of the first clinical trial subject in a Phase III clinical trial of the licensed product. If this event does not occur before December 31, 2011, then this amount will be due on this date; and


iv)
$8,000,000 on the date of first receipt of a NDA for the licensed product from the FDA or equivalent approval from a government agency in another country. If this event does not occur before December 31, 2013, then this amount will be due on this date.





3.     MEPL must pay Novogen royalties of 5.0% of all net sales and 25% of commercialization income for the term of the license. The royalty rate is reduced by 50% if the licensed patent rights in any country or territory expire, lapse, are revoked, do not exist or are assigned to MEPL and the product is entirely manufactured and supplied in such country.





4.     Minimum royalties of $3,000,000 per year are payable following the date of first receipt of an NDA for a licensed product from the FDA (or equivalent approval from a government agency in any other country) until the expiration of the term.





No license fees have been accrued in respect of triphendiol or NV-143 at March 31, 2010.





License Agreement for NV-128





On August 4, 2009, the Company entered into a license agreement with Novogen pursuant to which Novogen granted to MEPL an exclusive, worldwide, non-transferable license under its patents and patent applications and in the intellectual property rights related to its know how to conduct clinical trials, commercialize and distribute NV-128 (the “NV-128 Licence Agreement”). NV-128 is an investigational cancer compound which has been shown in pre-clinical laboratory studies to promote cancer cell death by targeting a pro-survival regulatory pathway (the AKT-mTOR pathway). The NV-128 License Agreement covers the use of NV-128 in the field of prevention, treatment and cure of cancer in humans delivered in all forms except topical applications.





14


The NV-128 License Agreement remains in effect until (i) the expiration or lapsing of the last relevant patents or patent applications in the world or (ii) Novogen’s assignment to MEPL of the last relevant patents or patent applications in the world so that MEPL may assume the filing, prosecution and maintenance of such patents or patent applications. Thereafter, the license becomes a non-exclusive, perpetual and irrevocable license covering any remaining intellectual property rights related to the know how with respect to NV-128.





1.     The Company paid $1,500,000 to Novogen Research in August 2009, which was the first lump sum license fee payment under the terms of the license agreement.





2.     Future amounts payable to Novogen upon the achievement of certain milestones are as follows:





i)
$1,000,000 on the date an IND for the licensed product goes into effect or the equivalent approval of a government agency is obtained in another country. If this event does not occur before December 31, 2011 then this amount will be due on this date;





ii)
$2,000,000 on the date of enrollment of the first clinical trial subject in a Phase II clinical trial of the licensed product. If this event does not occur before December 31, 2012, then this amount will be due on this date;





iii)
$3,000,000 on the date of enrollment of the first clinical trial subject in a Phase III clinical trial of the licensed product. If this event does not occur before December 31, 2014, then this amount will be due on this date; and





iv)
$8,000,000 on the date of first receipt of a NDA for the licensed product from the FDA or equivalent approval from a government agency in another country. If this event does not occur before December 31, 2017, then this amount will be due on this date.





3.     MEPL must pay Novogen royalties of 5.0% of all net sales and 25% of commercialization income for the term of the license.





4.     Minimum royalties of $3,000,000 per year are payable following the date of first receipt of an NDA for a licensed product from the FDA (or equivalent approval from a government agency in any other country) until the expiration of the term.





The license agreement is able to be cancelled without penalty by MEPL by giving three months’ notice.





No license fees have been accrued in respect of  NV-128 at March 31, 2010.





Amended and Restated License Option Deed





On September 24, 2003, MEPL and Novogen entered into an Amended and Restated License Option Deed (the “License Option Deed”). The License Option deed grants MEPL an exclusive right to accept and an exclusive right to match any proposed dealing by Novogen of its intellectual property rights with a third party relating to synthetic compounds (other than phenoxodiol) that have known or potential applications in the field of prevention, treatment or cure of cancer in humans in all forms other than topical applications.





15


Amended and Restated Services Agreement





On September 24, 2003, the Company, Novogen and MEPL entered into an Amended and Restated Services Agreement (the “Services Agreement”). Under the terms of the Services Agreement, Novogen or its subsidiaries have agreed to provide services reasonably required by the Company relating to the development and commercialization of phenoxodiol and other licensed products, including triphendiol, NV-143 and NV-128. Novogen has agreed to provide these services at cost plus a 10% mark-up. The Company may terminate the Services Agreement on three months’ written notice to Novogen.





Transactions giving rise to expenditures amounting to $2,274,000 and $1,713,000 were made under the Services Agreement with Novogen during the nine months ended March 31, 2010 and 2009, respectively. Of these amounts, $1,649,000 and $1,111,000 related to service fees paid to Novogen for research and development services provided in the nine months ended March 31, 2010 and 2009, respectively, reflecting the time spent by Novogen research staff on the development of phenoxodiol, triphendiol, NV-143 and NV-128. Additionally, $625,000 and $602,000 of the total expenditures during the nine months ended March 31, 2010 and 2009, respectively, related to costs incurred for administration and accounting services provided by Novogen.





At March 31, 2010 and 2009, $521,000 and $194,000, respectively, were due and owing to Novogen under the Services Agreement and are included in amounts due to related company.





Manufacturing License and Supply Agreement





On September 24, 2003, MEPL and Novogen entered into an amended and restated manufacturing license and supply agreement (the “Manufacturing License and Supply Agreement”). Under the terms of the Manufacturing License and Supply Agreement, MEPL has granted to Novogen an exclusive, non-transferable sub license to manufacture and supply phenoxodiol in its primary manufactured form. Novogen has agreed to supply phenoxodiol to MEPL for the clinical trial development program and phenoxodiol’s ultimate commercial use. Phenoxodiol supplied by Novogen under the terms of this agreement will be charged at cost plus a 50% markup.





There were no transactions under the Manufacturing License and Supply Agreement with Novogen during the nine months ended March 31, 2010 and 2009.





At March 31, 2010 and 2009 no amount was due and owing to Novogen under the Manufacturing License and Supply Agreement.





Novogen has taken the strategic decision not to manufacture large scale Active Pharmaceutical Ingredients for cancer drugs, including phenoxodiol, as these can be more economically supplied by third parties with particular expertise in this area.





16


6. Equity





The Company entered into a Securities Subscription Agreement dated as of July 28, 2008 with Novogen and OppenheimerFunds, Inc. (“Oppenheimer”) pursuant to which the Company sold 290,829 and 170,000 shares of common stock to Novogen and Oppenheimer, respectively, with Oppenheimer acting as adviser to each of the following parties severally and not jointly: (i) Oppenheimer International Growth Fund; (ii) Mass Mutual International Equity Fund; (iii) Oppenheimer International Growth Fund/VA; (iv) AZL Oppenheimer International Growth Fund; (v) OFITC International Growth Fund; and (vi) OFI International Equity Fund, at a purchase price of $21.70 per share, the consolidated closing bid price of the Company’s common stock as quoted by the Nasdaq Market Intelligence Desk at 4:00 PM EDST on July 28, 2008.  The shares were registered under the Securities Act of 1933, as amended (the “Securities Act”), under a Shelf Registration Statement on Form S-3 (File No. 333-149807). The Company received net proceeds of $9.8 million from the sale of the shares.





Following the closing of the registered direct offering described above in July 2008, Novogen retained approximately 71.3% of the Company’s common stock.





In July 2008, the Company also issued a warrant to Mr. John O’Connor exercisable for 4,608 shares of common stock, as consideration for investor relations services rendered by him to the Company. The warrant has an exercise price of $21.70 per share. The warrant may be exercised immediately and expires five years from the date of issuance, on July 30, 2013. The warrant has not been registered under the Securities Act. The Company issued the warrant to Mr. O’Connor in a private placement made in reliance upon the exemption from securities registration afforded by Section 4(2) of the Securities Act.





In January 2009, the Company filed a registration statement on Form S-8 (File No. 333-156985) with the SEC registering shares of common stock eligible for issuance under the Marshall Edwards, Inc. 2008 Stock Omnibus Equity Compensation Plan.





In January 2009, the Company issued a stock option exercisable for 5,000 shares of common stock to Associate Professor Gil Mor of Yale University in recognition of his contribution to the development of phenoxodiol under the Marshall Edwards, Inc. 2008 Stock Omnibus Equity Compensation Plan. The options have an exercise price of $6.30. The options are exercisable immediately and expire five years from date of issue.





On March 29, 2010, the Company filed a Certificate of Amendment to the Company’s Restated Certificate of Incorporation in order to effect a 1-for-10 reverse stock split of the Company’s common stock effective as of the opening of trading of the Company’s common stock on Nasdaq on Wednesday, March 31, 2010. As a result of the reverse stock split, every 10 shares of the Company’s issued and outstanding common stock were combined into one share of common stock. The reverse stock split did not change the number of authorized shares of the Company’s common stock. No fractional shares of common stock were issued as a result of the reverse stock split. Holders of common stock who, as a result of the reverse stock split, would otherwise have received a fractional share of common stock, are entitled to receive a cash amount equal to the proceeds attributable to the sale of such fractional shares of common stock following the aggregation and sale by the Company’s transfer agent of all fractional shares of common stock otherwise issuable. Following the reverse stock split, the Company expects to have approximately 7,346,323 shares of common stock outstanding.





17


The reverse stock split affected all shares of the Company’s common stock that were outstanding immediately prior to the effective time of the reverse stock split. For the purpose this report the Company has adjusted all share data presented retrospectively to incorporate the 1-for-10 reverse stock split.





7. Contingent Liabilities





Under the terms of the license agreements with Novogen, milestone license fee payments are payable upon achieving certain milestones. Details of the payments due under these agreements are detailed in Note 5 “Related Party Transactions.” The license agreements are subject to termination provisions.





8.Significant Events after Balance Date





On April 23, 2010, the Company appointed Dr. Daniel P. Gold as President and Chief Executive Officer of the Company.





Since October 2009, Dr. Gold has been Managing Partner of Theragence, Inc., a service provider that focuses on optimizing biopharmaceutical product development, which he co-founded. From July 2008 to May 2009, Dr. Gold was President and Chief Executive Officer of Prospect Therapeutics, a clinical stage, oncology focused, biotechnology company. From January 2000 to May 2009, Dr. Gold was Chief Scientific Officer of Favrille, Inc., a biopharmaceutical company that focused on the development and commercialization of immunotherapies for the treatment of cancer and other diseases of the immune system, which he founded. Dr. Gold was a member of the Executive Council of the Sabin Cancer Vaccine Consortium from 2004 to 2006 and a member of the board of directors of the San Diego chapter of the Leukemia and Lymphoma Society from 1998 to 2003. Dr. Gold received a Bachelors degree in biology from University of California Los Angeles and received a Doctorate degree from Tufts University in Pathology/Immunology.





Pursuant to the terms of Dr. Gold’s Employment Letter, Dr. Gold is also entitled receive options to purchase 220,390 shares of the Company’s common stock in two separate tranches. The first tranche of options to purchase 110,195 shares of common stock of the Company was granted to Dr. Gold upon his appointment as President and Chief Executive Officer on April 23, 2010, with an exercise price of $5.05 per share equal to the closing price of the Company’s common stock on April 23, 2010. The second tranche of options to purchase 110,195 shares of common stock of the Company will be granted to Dr. Gold no later than thirty (30) days following the public release of the Company’s Ovature study results. Of Dr. Gold’s options, 25% will vest one year from the effective date of the Employment Letter and, thereafter, the remaining 75% of Dr. Gold’s options will vest in equal monthly installments over the following thirty-six (36) months. In the event of a Change in Control of the Company, as defined in the Employment Letter, Dr. Gold’s options will become fully vested. Dr. Gold options are issued outside the Company’s 2008 Stock Omnibus Equity Compensation Plan.





The subsequent event information has been evaluated up to the date of filing this report on Form 10-Q.





18


Item 2:                 Management’s Discussion and Analysis of Financial Condition and Results of Operation





Special Note Regarding Forward-Looking Statements




This Quarterly Report on Form 10-Q includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”) and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). All statements other than statements of historical facts contained in this Quarterly Report, including statements regarding the future financial position, business strategy and plans and objectives of management for future operations, are forward-looking statements. The words “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “should,” “plan,” “expect,” and similar expressions, as they relate to us, are intended to identify forward-looking statements. We have based these forward-looking statements largely on current expectations and projections about future events and financial trends that we believe may affect our financial condition, results of operations, business strategy and financial needs. These forward-looking statements are subject to a number of risks, uncertainties and assumptions, including, among other things:




our inability to obtain required additional financing or financing available to us on acceptable terms, particularly in the context of the global financial crisis;our inability to maintain or enter into, and our dependence upon, collaboration or contractual arrangements necessary for the clinical development of phenoxodiol and other drug candidates;our limited operating history;our failure to successfully commercialize our product candidates;our termination of new enrollment into the OVATURE Phase III clinical trial;costs and delays in the clinical development program and/or receipt of U.S. Food and Drug Administration (the “FDA”) or other required governmental approvals, or the failure to obtain such approvals, for our product candidates;uncertainties in clinical trial results;our inability to maintain or enter into, and the risks resulting from our dependence upon, collaboration or contractual arrangements necessary for the development, manufacture, commercialization, marketing, sales and distribution of any products;our inability to control the costs of manufacturing our products;continued cooperation and support of Novogen Limited, our parent company;competition and competitive factors;our inability to protect our patents or proprietary rights and obtain necessary rights to third party patents and intellectual property to operate our business;












19





our inability to operate our business without infringing the patents and proprietary rights of others;costs stemming from our defence against third party intellectual property infringement claims;difficulties in enforcement of civil liabilities against our officers and directors who are residents of jurisdictions outside the U.S.;general economic conditions;the failure of any products to gain market acceptance;technological changes;government regulation generally and the receipt of the regulatory approvals;changes in industry practice; andone-time events.


These risks are not exhaustive. Other sections of this Quarterly Report on Form 10-Q may include additional factors which could adversely impact our business and financial performance. In addition, our business and financial performance may be affected by the factors that are discussed under “Risk Factors” in the Annual Report on Form 10-K for the year ended June 30, 2009. Moreover, we operate in a very competitive and rapidly changing environment. New risk factors emerge from time to time and it is not possible for us to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements.





You should not rely upon forward looking statements as predictions of future events. We cannot assure you that the events and circumstances reflected in the forward looking statements will be achieved or occur. Although we believe that the expectations reflected in the forward looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements.





The following discussion is qualified in its entirety by, and should be read in conjunction with, the more detailed information set forth in the financial statements and the notes thereto appearing elsewhere in this Quarterly Report on Form 10-Q.




Overview





Our main focus since commencing operations has been to undertake human clinical testing of phenoxodiol. Our operations were expanded to include the additional licensed drug candidates triphendiol and NV-143. In August 2009, we entered into a third license agreement for the drug candidate NV-128. During fiscal year 2007, we commenced the Phase III clinical trial (known as “OVATURE”).





20


We reached agreement under the Special Protocol Assessment  (“SPA”) process with the FDA on the design of our OVATURE pivotal study protocol for phenoxodiol. The trial is designed to test the ability of phenoxodiol to restore sensitivity of late-stage ovarian cancers to carboplatin, a standard form of therapy for ovarian cancer. The SPA was inactivated coincident with the premature termination of enrolment.





In April 2009, we announced the termination of enrollment into the OVATURE Phase III trial and our intention to undertake an un-blinded analysis of the available data from the trial.  The ongoing patients enrolled in the trial at this time will continue their treatment according to the study protocol. However, we ceased recruiting new patients and the available data from 142 completed and ongoing patients will be analyzed for safety and efficacy outcomes.





Clinical Product Developments





In September 2009, we released data demonstrating that the efficacy of NV-128 in animal xenograft models is achieved without apparent toxicity. NV-128 is a novel flavonoid small molecule inhibitor, capable of inhibiting both mTORC1 and mTORC2 pathways which are central to the aberrant proliferative capacity of both mature cancer cells and cancer stem cells. The data demonstrated that NV-128 has much greater safety than some other mTOR inhibitors in mice bearing human ovarian cancer xenografts. Additional data released reported that NV-128 was judged to be without cardiac toxicity, further indicating the likely safety of NV-128 in clinical use.





Corporate developments





On December 1, 2009, Novogen advised that its CEO and Managing Director Mr. Christopher Naughton ceased his employment, correspondingly Mr. Naughton's position as CEO of Marshall Edwards also ceased at this time. On February 5, 2010, Mr. Naughton resigned from being a director of the Company. Novogen’s CFO Mr. David Seaton was appointed acting CEO of the Group and he acted in that capacity until our new CEO, Dr. Daniel P. Gold was appointed President and Chief Executive Officer of Marshall Edwards on April 23, 2010. On April 30, 2010 Dr. Gold was appointed to serve as a member on the Board of Directors of the Company.





In September 2009, we received a letter from The Nasdaq Stock Market notifying us that for the previous 30 consecutive business days the bid price of our common stock closed below the minimum $1.00 per share requirement for continued inclusion on the Nasdaq Global Market under Nasdaq Rule 5450(a)(1). According to Nasdaq's letter, we would be afforded a grace period of 180 calendar days, or until March 15, 2010, to regain compliance in accordance with Nasdaq Rule 5810(c)(3)(A). In order to regain compliance, shares of our common stock must maintain a minimum bid closing price of at least $1.00 per share for a minimum of ten consecutive business days during the grace period. On March 16, 2010, we received notice from The Nasdaq Stock Market that we had not regained compliance and that we would be suspended from The Nasdaq Global Market on March 25, 2010, unless we requested a hearing. On March 23, 2010 we requested a hearing before the Nasdaq Hearings Panel. On March 29, 2010, our stockholders approved an amendment to the Company's Restated Certificate of Incorporation to effect a reverse stock split of the Company's common stock at a 1-for-10 reverse split ratio. The reverse stock split of our outstanding common stock was effected on March 31, 2010 on a 1-for-10 split adjusted basis.





21


Following the reverse stock split, the closing bid price of our common stock closed above the $1.00 minimum requirement for ten consecutive trading days. We have now received notification from The Nasdaq Stock Market that the we have regained compliance with the $1.00 minimum closing bid price in accordance with the Nasdaq Listing Rule 5450(a)(1). The Nasdaq Hearings Listing Qualifications Panel has determined to continue the listing of our securities on the Nasdaq Stock Market and, therefore, the hearing before the Hearings Listing Qualifications Panel has been cancelled. For the purpose of this report we have adjusted all share data presented retrospectively to incorporate the 1-for-10 reverse stock split.





At March 31, 2010 we had cash balances of approximately $11 million which we intend to allocate to completing the OVATURE data analysis of 142 patients, pursuing negotiations for out-licensing phenoxodiol should evidence of efficacy and safety emerge from the OVATURE analysis, initiating the triphendiol clinical program and continuing the pre-clinical program for NV-128.





We believe that our existing cash resources will be sufficient to satisfy our current operating plan until mid-2011. Changes in our research and development plans or other changes affecting our operating expenses may affect actual future consumption of existing cash resources. In any event, however, we will require additional financing to fund our operations in the future including the continued development of triphendiol and NV-128.





As of March 31, 2010, we had accumulated losses of $68,965,000.





We have not generated any revenues from operations since inception other than interest on cash assets. We have incurred losses since inception and expect to incur operating losses and generate negative cash flows from operations for the foreseeable future.





Expenses to date have consisted primarily of costs associated with conducting the clinical trials of phenoxodiol, including OVATURE, costs incurred under the Phenoxodiol License Agreement, as amended, the License Agreement for Triphendiol and NV-143, the License Agreement from NV-128, the Services Agreement and the Manufacturing License and Supply Agreements with Novogen and its subsidiaries, including the costs of the clinical trial drug supplies.





To date, operations have been funded primarily through the sale of equity securities.





As of the date of this Quarterly Report, Novogen owns approximately 71.3% of the outstanding shares of our common stock.





22


Critical Accounting Estimates





The preparation of the consolidated financial statements in conformity with accounting principles generally accepted in the U.S. requires management to make estimates and assumptions that affect the amounts reported in the financial statements and the accompanying notes. Actual results could differ from those estimates.





Clinical Trials Expenses





Estimates have been used in determining the expense liability under certain clinical trial contracts where services have been performed but not yet invoiced. The actual costs of those services could differ in amount and timing from the estimates used in completing the financial statements.





Generally the costs, and therefore estimates, associated with clinical trial contracts are based on the number of patients, drug administration cycles, the type of treatment and the outcome being measured. The length of time before actual amounts can be determined will vary depending on length of the patient cycles and the timing of the invoices by the clinical trial partners.





Clinical trial expenses of $868,000 have been accrued at March 31, 2010. These estimates are based on the number of patients in each trial and the drug administration cycle.





At June 30, 2009 we had accrued $1,181,000 in relation to claims received for clinical trial expenses in connection with the termination of enrollment into the OVATURE Phase III clinical trial. Following negotiations we have paid $849,000 in final settlement of these claims.





Stock Based Compensation





On December 9, 2008, we adopted the Marshall Edwards, Inc. 2008 Stock Omnibus Equity Compensation Plan (the “2008 Stock Omnibus Equity Compensation Plan”) and cancelled the Marshall Edwards, Inc. Share Option Plan (the “Share Option Plan”). No options were issued under the Share Option Plan. The 2008 Stock Omnibus Equity Compensation Plan provides for the issuance of a maximum of 700,000 shares of common stock in connection with the grant of options and/or other stock-based or stock-denominated awards to our non-employee directors, officers, employees and advisors. To date, we have issued options exercisable for 5,000 shares of common stock under the 2008 Stock Omnibus Equity Compensation Plan.





We account for stock based payments by estimating the fair value of the options issued. The costs of these equity-settled transactions are determined using a binomial model to calculate the fair value at the date on which they are granted. With respect to the fair value of the warrant representing 4,608 warrant shares issued to Mr. John O’Connor on July 30, 2008, in consideration for investor relations services rendered, and stock options representing 5,000 shares of common stock issued to Associate Professor Gil Mor of Yale University on January 28, 2009, in recognition of his contribution to the development of phenoxodiol under the 2008 Stock Omnibus Equity Compensation Plan, the following assumptions were used:







23




July 30, 2008
January 28, 2009Dividend yield
0%
0%Expected volatility
81%
111%Historical volatility
81%
111%Risk-free interest rate
3.36%
1.70%Expected life of warrant
5 years
5 yearsWarrant fair value
$14.10
$5.00





The dividend yield reflects the assumption that the current dividend payout, which is zero, will continue with no anticipated increases. The expected life of the warrant is based on historical data and is not necessarily indicative of exercise patterns that may occur. The expected volatility reflects the assumption that the historical volatility is indicative of future trends, which may also not necessarily be the actual outcome.








Results of Operations





Three Months Ended March 31, 2010 and 2009





We recorded a consolidated loss of $2,213,000 and $1,904,000 for the three months ended March 31, 2010 and 2009, respectively.





Revenues: We received interest on cash assets and cash equivalents of $19,000 for the three months ended March 31, 2010 compared to $29,000 for the three months ended March 31, 2009. The decrease was due to lower cash balances and lower interest rates earned by our cash deposits.





Research and Development: Research and development expenses increased slightly by $14,000 to $1,559,000 for the three months ended March 31, 2010 compared to $1,545,000 for the three months ended March 31, 2009. The increase represents additional spending on developing triphendiol and NV-128, partially offset by cost savings associated with the termination of the enrollment in the OVATURE Phase III clinical trial, which is nearing completion.





Selling, General and Administrative:Selling, general and administrative expenses increased by $285,000 to $673,000 for the three months ended March 31, 2010 compared to $388,000 for the three months ended March 31, 2009. The increase was primarily due to costs associated with the reverse share split and costs incurred in the recruitment process for a new Chief Executive Officer, which were not incurred in the previous corresponding period.





Foreign exchange gains/(losses) are included in selling, general and administrative expenses and occur when revaluing cash denominated in foreign currencies and upon consolidation of our wholly owned subsidiary Marshall Edwards Pty Ltd (“MEPL”). MEPL uses U.S. dollars as its functional currency and also engages in transactions in foreign currencies. Further, MEPL’s accounts and financial statements are denominated in Australian dollars. Translation of MEPL’s financial statements into U.S. dollars did not have a material impact on our financial position.





24


However, exchange rates are volatile in the current market resulting from the global financial crisis and there is a possibility that foreign exchange gains/losses may have a material impact in future periods. At March 31, 2010, we had not established a foreign currency hedging program. Net foreign exchange losses during the three months ended March 31, 2010 were $20,000 compared with foreign exchange gains of $1,000 during the three months ended March 31, 2009.





Nine months Ended March 31, 2010 and 2009





We recorded a consolidated loss of $6,054,000 and $5,755,000 for the nine months ended March 31, 2010 and 2009, respectively.





Revenues: We received interest on cash assets and cash equivalents of $68,000 for the nine months ended March 31, 2010 compared to $201,000 for the nine months ended March 31, 2009. The decrease was due to lower cash balances and lower interest rates earned by our cash deposits.





Research and Development: Research and development expenses decreased $1,935,000 to $3,053,000 for the nine months ended March 31, 2010 compared to $4,988,000 for the nine months ended March 31, 2009. The reduction was due to the termination of the enrollment in the OVATURE Phase III clinical trial and associated cost savings, partially offset by increased spending on developing triphendiol and NV-128.





Selling, General and Administrative:Selling, general and administrative expenses increased by $602,000 to $1,569,000 for the nine months ended March 31, 2010 compared to $967,000 for the nine months ended March 31, 2009. The increase was primarily due to net foreign exchange movements (described below) combined with additional costs associated with the reverse share split and costs incurred in the recruitment process for a new Chief Executive Officer, which were not incurred in the previous corresponding period. These increases were partially offset by savings in legal fees associated with the shelf registration, which took place in the previous corresponding period, a reduction in investor relations costs and a reduction in share option expense which was incurred in the previous corresponding period and not repeated in this period.





Net foreign exchange losses during the nine months ended March 31, 2010 were $151,000 compared with foreign exchange gains of $558,000 during the nine months ended March 31, 2009.





Liquidity and Capital Resources





At March 31, 2010, we had cash resources of $11,341,000 compared to $19,067,000 at June 30, 2009. The decrease was due to the expenditures in the clinical trial program, the pre-clinical development of triphendiol and NV-128 and other corporate expenses incurred in the period. Funds are invested in short term money market accounts, pending use.





On July 28, 2008 we entered into a securities subscription agreement with Novogen and OppenheimerFunds, Inc. (“Oppenheimer”) pursuant to which we sold 290,829 and 170,000 shares of common stock to Novogen and Oppenheimer, respectively, with Oppenheimer acting as adviser to each of the following parties severally and not jointly:








25


(i) Oppenheimer International Growth Fund; (ii) Mass Mutual International Equity Fund; (iii) Oppenheimer International Growth Fund/VA; (iv) AZL Oppenheimer International Growth Fund; (v) OFITC International Growth Fund; and (vi) OFI International Equity Fund, at a purchase price of $21.70 per share, the consolidated closing bid price of our common stock on July 28, 2008. The shares were registered under the Securities Act of 1933, as amended (the “Securities Act”) under a Shelf Registration Statement on Form S-3 (File No. 333-149807). We received gross proceeds of $10 million from the sale of the shares.





Following the closing, in July 2008, of the registered direct offering described above, Novogen retained approximately 71.3% of our common stock.





In July 2008, we issued a warrant to Mr. John O’Connor exercisable for 4,608 shares of common stock, as consideration for investor relation services rendered by him to us. The warrant has an exercise price of $21.70 per share. The warrant may be exercised immediately and expires five years from the date of issuance, on July 30, 2013. The warrant has not been registered under the Securities Act. We issued the warrant to Mr. O’Connor in a private placement made in reliance upon the exemption from securities registration afforded by Section 4(2) of the Securities Act.





In January 2009, we issued a stock option exercisable for 5,000 shares of common stock to Associate Professor Gil Mor of Yale University in recognition of his contribution to the development of phenoxodiol under the Marshall Edwards, Inc 2008 Stock Omnibus Equity Compensation Plan. The option has an exercise price of $6.30 per share of common stock. The options are exercisable immediately and expire five years from date of issue, on January 28, 2014.





Source and Uses of Cash





Cash Used in Operating Activities





Cash used in operating activities for the nine months ended March 31, 2010 was $7,726,000 compared to $6,469,000 for the same period in 2009. The increase in cash used primarily relates to the payment of the NV-128 licence fee of $1.5 million under the terms of the NV-128 licence agreement, partially offset by cash savings associated with reduced research and development expenditure.





Cash Requirements





We intend to allocate our current funds of approximately $11.3 million to completing the OVATURE data analysis of 142 patients, pursuing negotiations for out-licensing phenoxodiol should evidence of efficacy and safety emerge from the OVATURE analysis. We also intend to continue the clinical development of the drug candidate triphendiol and to continue the pre-clinical development of NV-128. In August 2009 we completed negotiations with Novogen to in-license the mTOR inhibitor NV-128, which has shown compelling pre clinical results to date. In consideration of the license granted to us we paid Novogen a license fee of $1,500,000 in August, 2009.





26


Ongoing operations, including the conduct of the pre clinical and clinical trial program, will continue to consume cash resources without generating revenues. We will require additional financing to fund our operations in the future. We cannot assure you that we will be able to raise the funds, necessary to fund our programs, on favorable terms to us or at all.








27


Payments to Novogen





Future payments to Novogen under the terms of the Phenoxodiol License Agreement, as amended and the License Agreement for Triphendiol and NV-143 and the License Agreement for NV-128 are detailed in Note 5 of the financial statements “Related Party Transactions” on page 12 of this Quarterly Report on Form 10-Q.





We will also be required to make payments to Novogen under the Services Agreement and Manufacturing License and Supply Agreement if future clinical supplies of drug product are sourced from Novogen.





We do not intend to incur any significant capital expenditures in the foreseeable future.





Off-Balance Sheet Arrangements





We do not currently have any off-balance sheet arrangements.





Contractual Obligations





For details of our contractual obligations at March 31, 2010 see Note 3 to the financial statements “Expenditure Commitments” on page 11 of this Quarterly Report on Form 10-Q.








28


Item 3:                      Quantitative and Qualitative Disclosures about Market Risk







Interest Rate Risk





Our exposure to market interest rates relates primarily to the investments of cash balances.





We have cash reserves held primarily in U.S. and Australian dollars and we place funds on deposit with financial institutions which are generally at call.





We do not use derivative financial instruments. We place our cash deposits with high credit quality financial institutions, and, by policy, limit the amount of credit exposure to any single counter-party. We are adverse to principal loss and we ensure the safety and preservation of our invested funds by limiting default risk, market risk and reinvestment risk.





We mitigate default risk by depositing funds with high credit quality financial institutions and by positioning the portfolio to respond appropriately to a significant reduction in a credit rating of any financial institution.





We have no interest rate exposure due to rate changes for long-term debt.





We do not consider the effects of interest rate movements to be a material risk to our financial condition.





Foreign Currency Risk





We conduct our business in various currencies, primarily in U.S. dollars and Australian dollars, Euros and British pounds. At March 31, 2010, we had not established a foreign currency hedging program. Net foreign exchange losses during the nine months ended March 31, 2010 were $151,000 compared with net exchange gains of $558,000 during the nine months ended March 31, 2009. Foreign exchange gains and losses occur upon consolidation of MEPL, which uses U.S. dollars as its functional currency and also engages in transactions in foreign currencies. MEPL’s accounts are denominated in Australian dollars. Translation of MEPL’s financial statements into U.S. dollars did not have a material impact on our financial position.





We do not consider the effects of foreign currency movements to be a material risk to our financial condition.











29


Item 4T:                 Controls and Procedures




Evaluation of Disclosure Controls and Procedures





At the end of the period covered by this Quarterly Report, our management, with the participation of our principal executive officer and principal financial officer, evaluated the effectiveness of our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act). Based on this evaluation, our principal executive officer and principal financial officer have concluded that our disclosure controls and procedures are effective to ensure that information required to be disclosed by us in reports that we file or submit under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in SEC rules and forms and have ensured that information required to be disclosed by us in such reports is accumulated and communicated to our management, including our principal executive officer and principal financial officer, as appropriate to allow timely decisions regarding  required disclosures.




There were no changes in our internal control over financial reporting during the period covered by this Quarterly Report that have materially affected, or are reasonably likely to materially affect, the Company’s internal control over financial reporting.








30


PART II  OTHER INFORMATION





Item 6:                 Exhibits








Exhibit Index








Exhibits





10.1
Employment letter, dated April 23, 2010, between Marshall Edwards, Inc. and Daniel Gold (1)31.1
Certification required by Rule 13a-14(a) or Rule 15d-14(a)31.2
Certification required by Rule 13a-14(a) or Rule 15d-14(a)32.1
Certification required by Rule 13a-14(b) or Rule 15d-14(b) and section 1350 of Chapter 63 of Title 18 of the United States Code (18 U.S.C 1350).








(1) Incorporated by reference to Exhibit 10.1 to Registrant’s Current Report on Form 8-K filed on April 26, 2010.








31


SIGNATURES











Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this Quarterly Report to be signed on its behalf by the undersigned, thereunto duly authorized.





MARSHALL EDWARDS, INC.





/s/ DAVIDSEATON








David Seaton


Chief Financial Officer


(Duly Authorized Officer and Principal Financial Officer)





Date: May 12, 2010





32


Exhibit 31.1


CERTIFICATION





I, Daniel Gold, certify that:







1.
I have reviewed this Quarterly Report on Form 10-Q of Marshall Edwards, Inc.;




2.
Based on my knowledge, this Quarterly Report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this Quarterly Report;




3.
Based on my knowledge, the financial statements, and other financial information included in this Quarterly Report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this Quarterly Report;




4.
The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:




(a)
Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within the entities, particularly during the period in which this Quarterly Report is being prepared;




(b)
Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;




(c)
Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in the Quarterly Report our conclusions about the effectiveness of this disclosure controls and procedures, as of the end of the period covered by this Quarterly Report based on such evaluation; and




(d)
Disclosed in this Quarterly Report any change in the registrant’s internal control over financial reporting that occurred during the registrants first fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting.




5.
The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors:




(a)
All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and




(b)
Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.














/s/ DANIELGOLD








Daniel Gold


Chief Executive Officer





Date: May 12, 2010


33


Exhibit 31.2


CERTIFICATION





I, David Seaton, certify that:







1.
I have reviewed this Quarterly Report on Form 10-Q of Marshall Edwards, Inc.;




2.
Based on my knowledge, this Quarterly Report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this Quarterly Report;




3.
Based on my knowledge, the financial statements, and other financial information included in this Quarterly Report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this Quarterly Report;




4.
The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:




(a)
Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within the entities, particularly during the period in which this Quarterly Report is being prepared;




(b)
Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;




(c)
Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in the Quarterly Report our conclusions about the effectiveness of this disclosure controls and procedures, as of the end of the period covered by this Quarterly Report based on such evaluation; and




(d)
Disclosed in this Quarterly Report any change in the registrant’s internal control over financial reporting that occurred during the registrants first fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting.




5.
The Company’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors:




(a)
All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and




(b)
Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.











/s/ DAVIDSEATON








David Seaton


Chief Financial Officer




Date: May 12, 2010





34


Exhibit 32.1





CERTIFICATION








Pursuant to the requirement set forth in Rule 13a-14(b) or Rule 15d-14(b) of the Securities Exchange Act of 1934, as amended, and Section 1350 of Chapter 63 of Title 18 of the United States Code (18 U.S.C. § 1350), Daniel Gold, the President and Chief Executive Officer of Marshall Edwards, Inc. (the “Registrant”), and David Seaton, Chief Financial Officer of the Registrant, hereby certifies that, to his knowledge:





1.
The Registrant’s Quarterly Report on Form 10-Q for the period ended March 31, 2010, (the “Form 10-Q”) to which this Certification is attached as Exhibit 32.1, fully complies with the requirements of Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934, as amended; and


2.
The information contained in the Form 10-Q fairly presents, in all material respects, the financial condition of the Registrant at the end of the period covered by the Form 10-Q and results of operations of the registrant for the period covered by the Form 10-Q.





These certifications accompanying the Form 10-Q to which they relate, are not deemed filed with the Securities and Exchange Commission and are not to be incorporated by reference into any filing of the registrant under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended (whether made before or after the date of the Form 10-Q), irrespective of any general incorporation language contained in such filing.










/s/ DANIELGOLD





Daniel Gold


Chief Executive Officer











/s/ DAVIDSEATON





David Seaton


Chief Financial Officer




Dated: May 12, 2010


35