[ DETERMINATION
OF INFRARED SPECTRUM AND DENSITY CERTIFICATE OF ANALYSIS TEST ITEM STIJDY NUMBER 41301942 STIJDY DIRECTOR

[

] NUMBER OF PA GES

6 SPONSOR:

TEST FACILITY: [

]

[ Introduction and Summary The infrared spectrum and density of the test item have been determined

. Experi menta

l testing wasconducted between OS June 2013 and 10 July 2013.
] The infrared spectrum of the test item wasconsistent with the proposed chemical composition

. The relative density of the test item wasdetermined tobe 1.06 at20.0 ±0 .5 °C. Test Item Details Name De scription Lot number Purity Date Received Storage Conditions Expiry Date amber colored liquid notsu pplied notsu pplied 30 January 2013 room temperature
in the dark under nitrogen 30 January 2015

] Co mpo
sitional informa

tion was supplie
d by the Sponsor for interpretation
of the infrared spectrum. The integrity of supplied data rela ting tothe identity, purity and stability of the test item

i sthe responsibility of the Sponsor.

Page
1 of6Study number: 41301942 Testing Details Infrared Spectrum The infrared spectrum was acquired using
aPerkin -E lmer Spectrum Two Fourier-transform infrared spectrophotometer. The test item wasscanned directly onthe diamond/zinc

selen ide crystal overthe wavenumber range4000

to400 cm·

1 • Conclusion It wasnot possible to positively confirm the test item composition from the infrared

s pectrum alone

. However

,noevidence wasfound in the infrared spectrum that contradicted the proposed chemical composition of the testit em.The infrared spectrum of the test item wasconsistent with the proposed chemical composition.

Page 2 of6Study number: 41301942 Density The determination wascarried out using
a procedure based onthe pycnometer method, Method A3 Relative Density of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method

1 09 of the OECD Guidelines for Testing Chemica

l sof 02 October 2012

.A glass pycnometer wasrinsed with water and then acetone prior to drying to constant mass

.Distilled water and test item were equilibrated
at -20 °C. The volume of the pycnometer wasmeasured by determining the massof distilled water required tofill the pycnometer

.The pycnometer wasthen emptied and dried to constant weight. The massof test item required tofill the pycnometer wasthen determined

.The equations used for the calculations areas follows:

D20-

p p= d(c
-a) and (b-a)

4- Density of waterat 4°C Where

: p a b c d D2o 4 = = = = = density (kglm
3 ) massof pycnometer (g) massof pycnometer filled with water (g) massof pycnometer filled with test item (g) density of water attest temperature (kglm

3 ) relative density Results of duplicate determinations
of relative den s ity areshown in the following table

: Measurement Mass of pycnometer (g) Mass of pycnometer and distilled waterat 20.4 oc•/20

.5 oct (g) Mass of pycnometer and testitem at 20.4 °C (g) Density of waterat 20

.4 oc•12 0 .5 oct (kg!m

3 ) Density (kg/m

3 ) Density of waterat 4 .0 OC (kg/m

3 ) Relative density Mean relative density: 1.06 Temperature: 20.0 ±0.5 °C Conclusion
Determination 1 . 25.3983 63.7437 66

.1080 998.12 1059

.7 999.97 1.06 The relative density of the test item wasdetermined tobe 1.06 at 20.0 ±0 .5 °C. Page 3 of6

2t 25.2398 63.2603 65.6206 998.10 1060.1 999.97 1.06Study number: 41301942 Archive Statement Unless instructed otherwise by the Sponsor, the Study Plan, all raw data (paper and electronic) and the final report will be retained in the [ ] archives for five years after which instructions will be sought as to further retention or disposal. Further retention or return of the data will be chargeable to the Sponsor

. No data will be discarded without contacting the Sponsor to obtain their written consent. Page 4 of6Study number: 41301942 GLP Compliance Statement

[
1 lstudy Number: Study Title: 41301942 [ ]

. Determination
of Infrared Spectrum and Density This study was performed
in compliance with UK GLP standards (Schedule

1, Good Laboratory Practice Regulation

s 1999 (SI 1999/3106 as amended by SI 2004/0994)). These Regulations are in accordance with GLP standards published
as OECD Principles on Good Laboratory Practice (revised 1997, ENV/MC/CHEM(98)17);

and are in accordance with, and implement, the requirements of Directives 2004/9/EC and 2004/1 0/EC. These principles are compatible with Good Laboratory Practice regulations specified by regulatory authorities throughout the European Community, the U nited State
s (EPA and FDA), and Japan (Mlll.W, MAFF and METI). Thi s certificate of analysis report accurately reflects the procedures

u s ed and data generated. There were no c ir cumstances considered to have affected the integrity of the s tudy or the validity of the data. [

] Signed:

2 3 AUG 2013 D a te: .......

.................................................

.. Study Director PageS of6Study number: 41301942 Quality Assurance Report I Study Number: Study Title: 41301942 [
1: Determination of Infrared Spectrum and Density The general facilities and activities are inspected at least once a year and the re sults are reported to the relevant responsible person and management. Study-related procedures conducted
at the test facility were audited and inspected. The details of these audits and inspections are given below. Reported to the relevant Dates and Types of QA Inspections
Study Director and Test Facility Management Date of Inspection Type of Inspection Phase Inspected Report Date 12 June 2013 Study Plan Verification

N / A

12 June 2013 1 0 Jul y 2013 Study- based Infrared Spectrum

10 July 2013 3 July 2013 Process

-based Density

3 July 2013 14 August 2013 Report Audit N/A

14 August 2013 This statement confirms that this certificate of analysis report reflects the raw data and the procedures followed

. Quality Assurance: [

] UIHC

: 2 3 AUG 2013 Page 6 of6