Exhibit
10.1 


MEDEFILE
INTERNATIONAL, INC.

SECURITIES PURCHASE AGREEMENT


This
Securities Purchase Agreement (this “Agreement”)
is made and entered into as of _________, 2015, by and among MedeFile International, Inc.,
a Nevada corporation (the “Company”), and each of the purchasers named on the signature pages attached
hereto (collectively, the “Purchasers” and individually, a “Purchaser”).


Recitals


 


		A.	The
                                         Company desires to issue and sell to the Purchasers, and the Purchasers desire to Purchase
                                         from the Company, up to 180,000,000 shares of common stock of the Company, on the terms
                                         and subject to the conditions set forth in this Securities Purchase Agreement.



		B.	The
                                         Company and each Purchaser are executing and delivering this Agreement in reliance upon
                                         the exemption from securities registration afforded by the provisions of Regulation D
                                         (“Regulation D”), as promulgated by the United States Securities and Exchange
                                         Commission (the “SEC”) under the Securities Act of 1933, as amended (the
                                         “Securities Act”).



The
parties hereto agree as follows:


1.                 
Agreement To Purchase And Sell Stock.


(a)              
Authorization. The Company’s Board of Directors has authorized the issuance and sale, pursuant to the terms and conditions
of this Agreement, of up to 180,000,000 shares of common stock (the “Shares”).


(b)              
Agreement to Purchase and Sell Shares. On the terms and subject to the conditions contained in this Agreement, each Purchaser
agrees to purchase, and the Company agrees to sell and issue to each Purchaser, at Closing (as defined below), that number of
Shares set forth on such Purchaser’s signature page, at a purchase price of $0.00222 per Share.


(c)               
Use of Proceeds. The Company intends to apply the net proceeds from the sale of the Shares for working capital and general
corporate purposes, as well as for strategic purposes in connection with selected acquisitions that may be considered in the future
to expand its product and service offerings.


(d)              
Obligations Several Not Joint. The obligations of each Purchaser under this Agreement are several and not joint with the obligations
of any other Purchaser, and no Purchaser shall be responsible in any way for the performance of the obligations of any other Purchaser
under this Agreement. Nothing contained herein, and no action taken by any Purchaser pursuant hereto, shall be deemed to constitute
the Purchasers as a partnership, an association, a joint venture or any other kind of entity, or create a presumption that the
Purchasers are in any way acting in concert or as a group with respect to such obligations or the transactions contemplated by
this Agreement. Each Purchaser shall be entitled to independently protect and enforce its rights, including without limitation
the rights arising out of this Agreement, and it shall not be necessary for any other Purchaser to be joined as an additional
party in any proceeding for such purpose.



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2.                 
Closing. The closing of the purchase and sale of the Shares shall take place
at the offices of Sichenzia Ross Friedman Ference LLP, 61 Broadway, New York, New York 10006 (the “SRFF Offices”)
at 10:00 a.m. Eastern time on the date of this Agreement, or at such other time and place as the Company and Purchasers representing
a majority of the Shares being issued mutually agree upon (which time and place are referred to in this Agreement as the “Closing”).
At Closing, each Purchaser shall deliver to the Company, via wire transfer or a certified check, immediately available funds for
full payment of the purchase price for the Shares purchased by such Purchaser as specified in Section 1(b). Promptly following
the Closing, the Company shall deliver (or cause to be delivered by delivering an instruction letter to its transfer agent for
the issuance) to each Purchaser its Shares registered in the name of each Purchaser (or in such nominee name(s) as designated
by such Purchaser in the Stock Certificate Questionnaire (attached hereto as Appendix I) (the “Stock Certificate Questionnaire”),
representing the appropriate number of Shares based on the number of Shares to be purchased by such Purchaser as set forth on
such Purchaser’s signature page, and bearing the legend set forth in Section 4(j) herein. Closing documents may be delivered
by facsimile or electronically. The date of the Closing is referred to herein as the “Closing Date.”


3.                 
Representations and Warranties of The Company. The Company hereby represents
and warrants to each Purchaser that the statements in this Section 3 are true and correct:


(a)              
Organization, Good Standing and Qualification. The Company and each of its Subsidiaries is a corporation duly organized, validly
existing and in good standing under the laws of the jurisdiction in which it was formed. Each of the Company and its Subsidiaries
has all corporate power and authority required to carry on its business as presently conducted and as described in the SEC Documents
(as described below), and the Company has all corporate power and authority required to enter into this Agreement and the other
agreements, instruments and documents contemplated hereby, and to consummate the transactions contemplated hereby and thereby.
Each of the Company and its Subsidiaries is duly qualified as a foreign entity to do business and is in good standing in each
jurisdiction in which the failure to so qualify would have a Material Adverse Effect. As used in this Agreement “Subsidiaries”
means any entity in which the Company owns, directly or indirectly, 100% of the capital stock. Further, as used in this
Agreement, “Material Adverse Effect” means a material adverse effect on, or a material adverse change
in, or a group of such effects on or changes in, the business, operations, condition, financial or otherwise, results of operations,
prospects, assets or liabilities of the Company and its subsidiaries, taken as a whole.


(b)              
Capitalization. The capitalization of the Company, without including the Shares to be purchased pursuant to this Agreement,
is as follows:


(i)                
The authorized capital stock of the Company consists of 500,000,000 shares of common stock, par value $0.0001 per share (“Common
Stock”), and 10,000,000 shares of preferred stock, par value $0.0001 per share (“Preferred Stock”).



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(ii)              
As of the date of this Agreement, the issued and outstanding capital stock of the Company consisted of _________ shares of
Common Stock and 0 shares of Preferred Stock. The shares of issued and outstanding capital stock of the Company have been duly
authorized and validly issued, are fully paid and nonassessable and have not been issued in violation of or are not otherwise
subject to any preemptive or other similar rights. All such shares have been issued in compliance with applicable securities laws.


(iii)            
As of the date of this Agreement, the Company had (a) 0 shares of Common Stock reserved for issuance upon exercise of outstanding
options granted under the Company’s incentive stock plans; and (b) _________ shares of Common Stock reserved for issuance
upon exercise of outstanding warrants.


(c)               
Subsidiaries. Except as set forth in the SEC Documents, (i) the Company does not have any subsidiaries, and does not own any
capital stock of, assets comprising the business of, obligations of, or any other interest (including any equity or partnership
interest) in, any person or entity; (ii) the Company owns, directly or indirectly, all of the capital stock or other equity interests
of each subsidiary free and clear of any liens, and all the issued and outstanding shares of capital stock of each subsidiary
are validly issued and are fully paid, non-assessable and free of preemptive and similar rights to subscribe for or purchase securities.


(d)              
Due Authorization. All corporate actions on the part of the Company necessary for the authorization, execution, delivery of,
and the performance of all obligations of the Company under this Agreement and the authorization, issuance, reservation for issuance
and delivery of all of the Shares being sold under this Agreement have been taken, no further consent or authorization of the
Company or the Board of Directors or its stockholders is required, and this Agreement constitutes the legal, valid and binding
obligation of the Company, enforceable against the Company in accordance with its terms, except (i) as may be limited by (A) applicable
bankruptcy, insolvency, reorganization or others laws of general application relating to or affecting the enforcement of creditors’
rights generally and (B) the effect of rules of law governing the availability of equitable remedies and (ii) as rights to indemnity
or contribution may be limited under federal or state securities laws or by principles of public policy thereunder.


(e)               
Valid Issuance of Shares.


(i)                
Shares. The Shares will be, upon payment therefore by the Purchasers in accordance with this Agreement, duly authorized, validly
issued, fully paid and non-assessable, free from all taxes, liens, claims, encumbrances with respect to the issuance of such Shares
and will not be subject to any pre-emptive rights or similar rights.


(ii)              
Compliance with Securities Laws. Subject to the accuracy of the representations made by the Purchasers in Section 4 hereof,
the Shares (assuming no unlawful redistribution of the Shares by the Purchasers or other parties as of the date hereof) will be
issued to the Purchasers in compliance with applicable exemptions from (A) the registration and prospectus delivery requirements
of the Securities Act and (B) the registration and qualification requirements of all applicable securities laws of the states
of the United States.



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(f)               
Consents and Approvals. No consent, approval, order or authorization of, or registration, qualification, designation, declaration
or filing with, or notice to, any federal, state or local governmental authority or self-regulatory agency or any other person
on the part of the Company is required in connection with the issuance of the Shares to the Purchasers, or the consummation of
the other transactions contemplated by this Agreement, except (i) such filings as have been made prior to the date hereof and
(ii) such additional post-Closing filings as may be required to comply with applicable state and federal securities laws.


(g)              
Non-Contravention. The execution, delivery and performance of this Agreement by the Company, and the consummation by the Company
of the transactions contemplated hereby (including issuance of the Shares), do not: (i) contravene or conflict with the Articles
of Incorporation of the Company, as amended to date (the “Articles of Incorporation”), or the Bylaws
of the Company, as amended to date (the “Bylaws”) or the organizational documents of any Subsidiary;
(ii) constitute a violation of any provision of any federal, state, local or foreign law, rule, regulation, order or decree applicable
to the Company; or (iii) constitute a default (or an event that with notice or lapse of time or both would become a default) or
require any consent under, give rise to any right of termination, cancellation or acceleration of, or to a loss of any material
benefit to which the Company is entitled under, or result in the creation or imposition of any lien, claim or encumbrance on any
assets of the Company under, any material contract to which the Company is a party or any material permit, license or similar
right relating to the Company or by which the Company may be bound or affected.


(h)              
Litigation. Except as set forth in the SEC Documents, there is no action, suit, proceeding, claim, arbitration or investigation
(“Action”) pending or, to the Company’s knowledge, threatened in writing: (i) against the
Company or any of its Subsidiaries, their respective activities, properties or assets, or any officer, director or employee of
the Company or any of its Subsidiaries in connection with such officer’s, director’s or employee’s relationship
with, or actions taken on behalf of, the Company or any of its Subsidiaries, that is reasonably likely to have a Material Adverse
Effect; or (ii) that seeks to prevent, enjoin, alter, challenge or delay the transactions contemplated by this Agreement (including
the issuance of the Shares). Neither the Company nor any of its Subsidiaries is a party to or subject to the provisions of, any
order, writ, injunction, judgment or decree of any court or government agency or instrumentality. No Action is currently pending
nor does the Company or any of its Subsidiaries intend to initiate any Action that is reasonably likely to have a Material Adverse
Effect.


(i)                
Compliance. The Company is not in violation or default of any provisions of the Articles of Incorporation or the Bylaws and
none of the Company’s Subsidiaries is in violation or default of any provisions of their respective organizational documents.
The Company and each of its Subsidiaries has complied and is currently in compliance with all applicable statutes, laws, rules,
regulations and orders of the United States of America and all states thereof, foreign countries and other governmental bodies
and agencies having jurisdiction over the Company’s or each subsidiary’s respective businesses or properties, except
for any instance of non-compliance that has not had, and would not reasonably be expected to have, a Material Adverse Effect.
Neither the Company nor any of its Subsidiaries is in default under or in violation of (and no event has occurred that has not
been waived that, with notice or lapse of time or both, would result in a default by the Company or any subsidiary under), nor
has the Company or any Subsidiary received notice of a claim that it is in default under or that it is in violation of, any indenture,
loan or credit agreement or any other agreement or instrument to which it is a party or by which it or any of its properties is
bound (whether or not such default or violation has been waived), except as does not, individually or in the aggregate, have or
reasonably be expected to result in a Material Adverse Effect.



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(j)                
Material Non-Public Information. The Company has not provided to the Purchasers any material non-public information other
than information related to the transactions contemplated by this Agreement, all of which information related to the transactions
contemplated hereby shall be disclosed by the Company pursuant to a Form 8-K the Company shall file within 4 business days hereof.
The Company understands and confirms that each Purchaser shall be relying on the foregoing representations in effecting transactions
in securities of the Company.


(k)              
SEC Documents.


(i)                
Reports. The Company has filed all reports, schedules, forms, statements and other documents required to be filed by it with
the SEC pursuant to the reporting requirements of the Securities Exchange Act of 1934, as amended (the “Exchange Act”),
and the rules and regulations promulgated thereunder. The Company has made available to the Purchasers prior to the date hereof
copies of its Annual Report on Form 10-K for the fiscal year ended December 31, 2013 (the “Form 10-K”),
its Quarterly Reports on Form 10-Q for the periods ended March 31, 2014, June 30, 2014 and September 30, 2014, respectively (the
“Forms 10-Q”) and any Current Report on Form 8-K for events occurring since December 31, 2013 (“Forms
8-K”) filed by the Company with the SEC (the Form 10-K, Forms 10-Q and the Forms 8-K (including all exhibits
thereto), together with any documents subsequently filed or furnished by the Company with the SEC are collectively referred to
herein as the “SEC Documents”). Each of the SEC Documents, as of the respective dates thereof (or, if
amended or superseded by a filing prior to the Closing Date, then on the date of such filing), did not contain any untrue statement
of a material fact or omit to state a material fact necessary in order to make the statements made therein, in light of the circumstances
under which they were made, not misleading. Each SEC Document, as it may have been subsequently amended by filings made by the
Company with the SEC prior to the date hereof, complied in all material respects with the requirements of the Exchange Act and
the rules and regulations of the SEC promulgated thereunder applicable to such SEC Document.


(ii)              
Sarbanes-Oxley. The Chief Executive Officer and the Chief Financial Officer of the Company have signed, and the Company has
furnished to the SEC, all certifications required by Sections 302 and 906 of the Sarbanes-Oxley Act of 2002. Except as set forth
in the SEC Documents, such certifications contain no qualifications or exceptions to the matters certified therein and have not
been modified or withdrawn; and neither the Company nor any of its officers has received notice from any governmental entity questioning
or challenging the accuracy, completeness, form or manner of filing or submission of such certifications. Except as set forth
in the SEC Documents, the Company is otherwise in compliance in all material respects with all applicable effective provisions
of the Sarbanes-Oxley Act of 2002 and the rules and regulations issued thereunder by the SEC. Except as set forth in the SEC Documents,
the Company has established disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for
the Company and designed such disclosure controls and procedures to ensure that information required to be disclosed by the Company
in the reports it files or submits under the Exchange Act is recorded, processed, summarized and reported, within the time periods
specified in the SEC’s rules and forms. The Company’s certifying officers have evaluated the effectiveness of the
Company’s disclosure controls and procedures as of the end of the period covered by the Company’s most recently filed
periodic report under the Exchange Act (such date, the “Evaluation Date”). The Company presented in its most
recently filed periodic report under the Exchange Act the conclusions of the certifying officers about the effectiveness of the
disclosure controls and procedures based on their evaluations as of the Evaluation Date. Since the Evaluation Date, there have
been no changes in the Company’s internal control over financial reporting (as such term is defined in the Exchange Act)
that has materially affected, or is reasonably likely to materially affect, the Company’s internal control over financial
reporting.



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(iii)            
Financial Statements. The financial statements of the Company in the SEC Documents present fairly, in accordance with United
States generally accepted accounting principles (“GAAP”), consistently applied, the financial position
of the Company as of the dates indicated, and the results of its operations and cash flows for the periods therein specified,
subject, in the case of unaudited financial statements for interim periods, to normal year-end audit adjustments.


(l)                
Absence of Certain Changes since the Balance Sheet Date. Except as set forth in the SEC Documents, since September 30, 2014,
the business and operations of the Company and each of its Subsidiaries have been conducted in the ordinary course consistent
with past practice, and there has not been:


(i)                
any declaration, setting aside or payment of any dividend or other distribution of the assets of the Company or any of its
Subsidiaries with respect to any shares of capital stock of the Company or any of its Subsidiaries or any repurchase, redemption
or other acquisition by the Company or any subsidiary of the Company of any outstanding shares of the Company’s capital
stock (and the Company has not made any agreements to do any of the foregoing);


(ii)              
any damage, destruction or loss, whether or not covered by insurance, except for such occurrences, individually and collectively,
that have not had, and would not reasonably be expected to have, a Material Adverse Effect;


(iii)            
any waiver by the Company or any of its Subsidiaries of a valuable right or of a material debt owed to it, except for such
waivers, individually and collectively, that have not had, and would not reasonably be expected to have, a Material Adverse Effect;


(iv)            
any material change or amendment to, or any waiver of any material right under a material contract or arrangement by which
the Company or any of its Subsidiaries or any of its or their respective assets or properties is bound or subject;



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(v)              
any change by the Company in its accounting principles, methods or practices or in the manner in which it keeps its accounting
books and records, except any such change required by a change in GAAP or by the SEC; or


(vi)            
any other event or condition of any character, except for such events and conditions that have not resulted, and are not expected
to result, either individually or collectively, in a Material Adverse Effect.


(m)            
Intellectual Property.


(i)                
Except as set forth in the SEC Documents, the Company and each of its Subsidiaries owns or possesses sufficient rights to
use all patents, patent rights, inventions, trade secrets, know-how, trademarks, service marks, trade names, copyrights, information
and other proprietary rights and processes (collectively, “Intellectual Property”), which are necessary
to conduct its or their respective businesses as currently conducted and as described in the SEC Documents free and clear of all
liens, encumbrances and other adverse claims, except where the failure to own or possess free and clear of all liens, encumbrances
and other adverse claims would not reasonably be expected to result, either individually or in the aggregate, in a Material Adverse
Effect.


(ii)              
Neither the Company nor any of its Subsidiaries has received any written notice of, nor has knowledge of, any infringement
of or conflict with rights of others with respect to any Intellectual Property and neither the Company nor any of its Subsidiaries
has knowledge of any infringement, misappropriation or other violation of any Intellectual Property by any third party, which,
in either case, either individually or in the aggregate, if the subject of an unfavorable decision, ruling or finding, would reasonably
be expected to have a Material Adverse Effect.


(iii)            
To the Company’s knowledge, none of the patent rights owned or licensed by the Company or any of its Subsidiaries are
unenforceable or invalid.


(iv)            
Each employee, consultant and contractor of the Company and each of its Subsidiaries who has had access to the Intellectual
Property has executed a valid and enforceable agreement to maintain the confidentiality of such Intellectual Property and assigning
all rights to the Company or such subsidiary to any inventions, improvements, discoveries or information relating to the business
of the Company or such subsidiary. The Company is not aware that any of its or its Subsidiaries’ employees is obligated
under any contract (including licenses, covenants or commitments of any nature) or other agreement, or subject to any judgment,
decree or order of any court or administrative agency, that would interfere with their duties to the Company or such subsidiary
or that would conflict with the Company’s or such subsidiary’s business.


(v)              
Neither the Company nor any of its Subsidiaries is subject to any “open source” or “copyleft” obligations
or otherwise required to make any public disclosure or general availability of source code either used or developed by the Company
or any of its Subsidiaries.



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(n)              
Registration Rights. Except as set forth in the SEC Documents, the Company is not currently subject to any agreement providing
any person or entity any rights (including piggyback registration rights) to have any securities of the Company registered with
the SEC or registered or qualified with any other governmental authority.


(o)              
Title to Property and Assets. Except as set forth in the SEC Documents (including without limitation, a lien held on the Company’s
assets held by Lyle Hauser), the properties and assets of the Company and its Subsidiaries are owned by the Company and its Subsidiaries
free and clear of all mortgages, deeds of trust, liens, charges, encumbrances and security interests except for (i) statutory
liens for the payment of current taxes that are not yet delinquent and (ii) liens, encumbrances and security interests that arise
in the ordinary course of business and do not in any material respect affect the properties and assets of the Company. With respect
to the property and assets it leases, the Company is in compliance with such leases in all material respects.


(p)              
Taxes. The Company and each of its Subsidiaries has filed or has valid extensions of the time to file all necessary federal,
state, and foreign income and franchise tax returns due prior to the date hereof and has paid or accrued all taxes shown as due
thereon, and the Company has no knowledge of any material tax deficiency that has been or might be asserted or threatened against
it or any of its Subsidiaries.


(q)              
Insurance. The Company and its Subsidiaries maintain insurance of the types and in the amounts that the Company reasonably
believes is prudent and adequate for its business and which is at least as extensive as is customary for other companies in the
Company’s industry, all of which insurance is in full force and effect.


(r)               
Labor Relations. No material labor dispute exists or, to the knowledge of the Company, is imminent with respect to any of
the employees of the Company or any of its Subsidiaries. No executive officer, to the knowledge of the Company, is, or is now
expected to be, in violation of any material term of any employment contract, confidentiality, disclosure or proprietary information
agreement or non-competition agreement, or any other contract or agreement or any restrictive covenant, and the continued employment
of each such executive officer does not subject the Company or any of its Subsidiaries to any liability with respect to any of
the foregoing matters.


(s)               
Internal Accounting Controls. The Company and its Subsidiaries maintain a system of internal accounting controls sufficient
to provide reasonable assurance that (i) transactions are executed in accordance with management’s general or specific
authorizations, (ii) transactions are recorded as necessary to permit preparation of financial statements in conformity with
GAAP and to maintain asset accountability, (iii) access to assets is permitted only in accordance with management’s general
or specific authorization and (iv) the recorded accountability for assets is compared with the existing assets at reasonable intervals
and appropriate action is taken with respect to any differences.


(t)                
Transactions With Officers and Directors. Except as set forth in the SEC Documents, none of the officers or directors of the
Company has entered into any transaction with the Company or any Subsidiary that would be required to be disclosed pursuant to
Item 404(a) or (c) of Regulation S-K of the SEC.



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(u)              
General Solicitation. Neither the Company nor any other person or entity authorized by the Company to act on its behalf has
engaged in a general solicitation or general advertising (within the meaning of Regulation D of the Securities Act) of investors
with respect to offers or sales of the Shares. The Company has offered the Shares for sale only to the Purchasers and certain
other “accredited investors” within the meaning of Rule 501 under the Securities Act.


(v)              
Listing Matters. The Common Stock of the Company is quoted on the OTCQB under the ticker symbol “MDFI.”


(w)            
Investment Company. The Company and each of its Subsidiaries is not now, and after the sale of the Shares under this Agreement
and the application of the net proceeds from the sale of the Shares described in Section 1(b) herein will not be, an “investment
company” within the meaning of the Investment Company Act of 1940, as amended.


(y)No
Integrated Offering. Neither the Company, nor any Affiliate of the Company, nor any person acting on its or their behalf
has, directly or indirectly, engaged in any form of general solicitation or general advertising with respect to any security or
made any offers or sales of any security or solicited any offers to buy any security, under circumstances that would cause the
offering or issuance of the Shares to be integrated with prior offerings by the Company for purposes of the Securities Act which
would cause Regulation D or any other applicable exemption from registration under the Securities Act to be unavailable, or would
cause any applicable state securities laws exemptions or any applicable stockholder approval provisions exemptions, including,
without limitation, under the rules and regulations of any national securities exchange or automated quotation system on which
any of the securities of the Company are listed or designated to be unavailable, nor will the Company take any action or steps
that would cause the offering or issuance of the Shares to be integrated with other offerings.


 


(z)Brokers.
Neither the Company nor any Subsidiary has any liability to pay any fees, commissions or other similar compensation to any
broker, finder, investment banker, financial advisor or other similar person in connection with the transactions contemplated
by this Agreement. The Purchasers shall have no obligation with respect to any fees or with respect to any claims made by or on
behalf of other persons for fees of a type contemplated in this Section that may be due in connection with the transactions contemplated
by this Agreement.


 


(aa)Application
of Takeover Protections. The Company and its Board of Directors have taken all necessary action, if any, in order to render
inapplicable any control share acquisition, business combination, poison pill (including any distribution under a rights agreement)
or other similar anti-takeover provision under the Company’s Articles of Incorporation (or similar charter documents) or
the laws of its state of incorporation that is or could become applicable to the Purchasers as a result of the Purchasers and
the Company fulfilling their obligations or exercising their rights under this Agreement, including without limitation as a result
of the Company’s issuance of the Shares and the Purchasers’ ownership of the Shares.


 



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(bb)Purchaser
Representations. The Company acknowledges and agrees that no Purchaser makes or has made any representation or warranties
with respect to the transactions contemplated hereby other than those specifically set forth in Section 4 hereof.


 


(cc)No
Disagreements with Accountants and Lawyers. There are no disagreements of any kind presently existing, or reasonably anticipated
by the Company to arise, between the Company and the accountants and lawyers formerly or presently employed by the Company.


 


(dd)Acknowledgment
Regarding Purchasers’ Purchase of Shares. The Company acknowledges and agrees that each of the Purchasers is acting
solely in the capacity of an arm’s length purchaser with respect to this Agreement and the transactions contemplated hereby.
The Company further acknowledges that no Purchaser is acting as a financial advisor or fiduciary of the Company (or in any similar
capacity) with respect to this Agreement and the transactions contemplated hereby and any advice given by any Purchaser or any
of their respective representatives or agents in connection with this Agreement and the transactions contemplated hereby is merely
incidental to the Purchasers’ purchase of the Shares. The Company further represents to each Purchaser that the Company’s
decision to enter into this Agreement has been based solely on the independent evaluation of the transactions contemplated hereby
by the Company and its representatives.


 


(ee)Manipulation
of Price.  The Company has not, and to its knowledge no one acting on its behalf has, (i) taken, directly or indirectly,
any action designed to cause or to result in the stabilization or manipulation of the price of any security of the Company to
facilitate the sale or resale of any of the Shares, (ii) sold, bid for, purchased, or, paid any compensation for soliciting purchases
of, any of the Shares or (iii) paid or agreed to pay to any person any compensation for soliciting another to purchase any other
securities of the Company, other than, in the case of clauses (ii) and (iii), compensation paid to the Company’s placement
agent, if any, and any approved broker-dealers in connection with the placement of the Shares.


 


(ff)Equal
Treatment of Purchasers. No consideration shall be offered or paid to any Purchaser to amend or consent to a waiver or modification
of any provision of any of this Agreement unless the same consideration is also offered to all of the Purchasers under this Agreement.
For clarification purposes, this provision constitutes a separate right granted to each Purchaser by the Company and negotiated
separately by each Purchaser, and is intended for the Company to treat the Purchasers as a class and shall not in any way be construed
as the Purchasers acting in concert or as a group with respect to the purchase, disposition or voting of Shares or otherwise.


 


4.                 
Representations, Warranties and Certain Agreements of The Purchasers. Each Purchaser
hereby represents and warrants to the Company, severally and not jointly, and agrees that:



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(a)              
Organization, Good Standing and Qualification. The Purchaser has all corporate, membership or partnership power and authority
required to enter into this Agreement and the other agreements, instruments and documents contemplated hereby, and to consummate
the transactions contemplated hereby and thereby.


(b)              
Authorization. The execution of this Agreement has been duly authorized by all necessary corporate, membership or partnership
action on the part of the Purchaser. This Agreement constitutes the Purchaser’s legal, valid and binding obligation, enforceable
in accordance with its terms, except (i) as may be limited by (A) applicable bankruptcy, insolvency, reorganization or other laws
of general application relating to or affecting the enforcement of creditors’ rights generally and (B) the effect of rules
of law governing the availability of equitable remedies and (ii) as rights to indemnity or contribution may be limited under federal
or state securities laws or by principles of public policy thereunder.


(c)               
Litigation. There is no Action pending to which the Purchaser is a party that is reasonably likely to prevent, enjoin, alter
or delay the transactions contemplated by this Agreement.


(d)              
Purchase for Own Account. The Shares are being acquired for investment for the Purchaser’s own account, not as a nominee
or agent, and not with a view to the public resale or distribution thereof within the meaning of the Securities Act, without prejudice,
however, to the Purchaser’s right at all times to sell or otherwise dispose of all or any part of such securities in compliance
with applicable federal and state securities laws and as otherwise contemplated by this Agreement. The Purchaser also represents
that it has not been formed for the specific purpose of acquiring the Shares.


(e)               
Investment Experience. The Purchaser understands that the purchase of the Shares involves substantial risk. The Purchaser
has experience as an investor in securities of companies and acknowledges that it can bear the economic risk of its investment
in the Shares and has such knowledge and experience in financial or business matters that it is capable of evaluating the merits
and risks of this investment in the Shares and protecting its own interests in connection with this investment.


(f)               
Accredited Investor Status. The Purchaser is an “accredited investor” within the meaning of Regulation D promulgated
under the Securities Act.


(g)              
Reliance Upon Purchaser’s Representations. The Purchaser understands that the issuance and sale of the Shares to it
will not be registered under the Securities Act on the ground that such issuance and sale will be exempt from registration under
the Securities Act pursuant to Section 4(a)(2) thereof, and that the Company’s reliance on such exemption is based on each
Purchaser’s representations set forth herein.


(h)              
Receipt of Information. The Purchaser has had an opportunity to ask questions and receive answers from the Company regarding
the terms and conditions of the issuance and sale of the Shares and the business, properties, prospects and financial condition
of the Company and to obtain any additional information requested and has received and considered all information it deems relevant
to make an informed decision to purchase the Shares. Neither such inquiries nor any other investigation conducted by or on behalf
of the Purchaser or its representatives or counsel shall modify, amend or affect the Purchaser’s right to rely on the truth,
accuracy and completeness of such information and the Company’s representations and warranties contained in this Agreement.
Without limiting the generality of the foregoing, the Purchaser hereby acknowledges receipt and careful review of the SEC Documents,
including all exhibits thereto,



    	11



    	 



    




(i)                
Restricted Securities. The Purchaser understands that the Shares have not been registered under the Securities Act and will
not sell, offer to sell, assign, pledge, hypothecate or otherwise transfer any of the Shares unless (i) pursuant to an effective
registration statement under the Securities Act, (ii) such holder provides the Company with an opinion of counsel, in form and
substance reasonably acceptable to the Company, to the effect that a sale, assignment or transfer of the Shares may be made without
registration under the Securities Act and the transferee agrees to be bound by the terms and conditions of this Agreement, or
(iii) such holder provides the Company with reasonable assurances (in the form of seller and broker representation letters) that
the Shares can be sold pursuant to Rule 144 promulgated under the Securities Act (“Rule 144”). Notwithstanding
anything to the contrary contained in this Agreement, the Purchaser may transfer (without restriction and without the need for
an opinion of counsel) the Shares to its Affiliates (as defined below) provided that each such Affiliate is an “accredited
investor” under Regulation D, and such Affiliate agrees to be bound by the terms and conditions of this Agreement and shall
have the rights of a Purchaser hereunder.


For
the purposes of this Agreement, an “Affiliate” of the Purchaser means any other person or entity directly
or indirectly controlling, controlled by or under direct or indirect common control with the Purchaser. For purposes of this definition,
“control” means the power to direct the management and policies of such person or firm, directly or
indirectly, whether through the ownership of voting securities, by contract or otherwise.


 


(j)                
Legends.


(i)                
Shares. The Purchaser agrees that the certificates for the Shares shall bear the following legend and that the Purchaser will
comply with the restrictions on transfer set forth in such legend:


“THESE
SECURITIES HAVE NOT BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE
UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY,
MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE
EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH
APPLICABLE STATE SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR TO SUCH EFFECT, THE SUBSTANCE OF
WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY.”



    	12



    	 



    




The
Company acknowledges and agrees that the Purchaser may from time to time pledge pursuant to a bona fide margin agreement with
a registered broker-dealer or grant a security interest in some or all of the Shares to a financial institution that is an “accredited
investor” as defined in Rule 501(a) under the Securities Act and who agrees to be bound by the provisions of this Agreement
and, if required under the terms of such arrangement, the Purchaser may transfer pledged or secured Shares to the pledgees or
secured parties. Further, no notice shall be required of such pledge. At the Purchaser’s expense, the Company will execute
and deliver such reasonable documentation as a pledgee or secured party of Shares may reasonably request in connection with a
pledge or transfer of the Shares, the preparation and filing of any required prospectus supplement under Rule 424(b)(3) under
the Securities Act or other applicable provision of the Securities Act to appropriately amend the list of selling stockholders
thereunder.


In
addition, the Purchaser agrees that the Company may place stop transfer orders with its transfer agent with respect to such certificates
in order to implement the restrictions on transfer set forth in this Agreement. The appropriate portion of the legend and the
stop transfer orders will be removed promptly (but in no event later than three (3) business days) upon delivery to the Company
of such satisfactory evidence as reasonably may be required by the Company that such legend or stop orders are not required to
ensure compliance with the Securities Act.


(k)              
Questionnaires. The Purchaser has completed or caused to be completed the Stock Certificate Questionnaire, and the answers
to such questionnaires are true and correct as of the date of this Agreement.


(l)                
Prohibited Transactions. During the last thirty (30) days prior to the date hereof, neither the Purchaser nor any Affiliate
of the Purchaser, foreign or domestic, has, directly or indirectly, effected or agreed to effect any “short sale”
(as defined in Rule 200 under Regulation SHO), whether or not against the box, established any “put equivalent position”
(as defined in Rule 16a-1(h) under the 1934 Act) with respect to the Common Stock, borrowed or pre-borrowed any shares of Common
Stock, or granted any other right (including, without limitation, any put or call option) with respect to the Common Stock or
with respect to any security that includes, relates to or derived any significant part of its value from the Common Stock or otherwise
sought to hedge its position in the Company’ securities (each, a “Prohibited Transaction”).


5.                 
Conditions to The Purchasers’ Obligations at the Closing.
The obligations of the Purchasers under Section 1(b) of this Agreement are subject to the fulfillment or waiver, on or
before the Closing, of each of the following conditions:


(a)              
Representations and Warranties True. Each of the representations and warranties of the Company contained in Section 3 shall
be true and correct in all material respects on and as of the date hereof (provided, however, that such materiality qualification
shall only apply to representations or warranties not otherwise qualified by materiality) and on and as of the date of the Closing
with the same effect as though such representations and warranties had been made as of the Closing; provided, however, that if
a representation and warranty is made as of a specific date, it shall be true and correct in all material respects only as of
such date.



    	13



    	 



    




(b)              
Performance. The Company shall have performed and complied in all material respects with all agreements, obligations and conditions
contained in this Agreement that are required to be performed or complied with by it on or before the Closing and shall have obtained
all approvals, consents and qualifications necessary to complete the purchase and sale described herein; provided, however,
that the Company may deliver to the Purchasers the original stock certificates for the Shares within five business days of the
Closing.


(c)               
Agreement. The Company shall have executed and delivered to the Purchasers this Agreement.


(d)              
Securities Exemptions. The offer and sale of the Shares to the Purchasers pursuant to this Agreement shall be exempt from
the registration requirements of the Securities Act and the registration and/or qualification requirements of all applicable state
securities laws.


(e)               
No Suspension of Trading or Listing of Common Stock. The Common Stock of the Company (i) shall be designated for quotation
on the OTCQB and (ii) shall not have been suspended from trading on the OTCQB.


(f)               
No Statute or Rule Challenging Transaction. No statute, rule, regulation, executive order, decree, ruling, injunction, action,
proceeding or interpretation shall have been enacted, entered, promulgated, endorsed or adopted by any court or governmental authority
of competent jurisdiction or any self-regulatory organization or the staff of any of the foregoing, having authority over the
matters contemplated hereby that questions the validity of, or challenges or prohibits the consummation of, any of the transactions
contemplated by this Agreement.


(g)              
Other Actions. The Company shall have executed such certificates, agreements, instruments and other documents, and taken such
other actions as shall be customary or reasonably requested by the Purchasers in connection with the transactions contemplated
hereby.


6.                 
Conditions to The Company’s Obligations at the Closing. The obligations
of the Company to the Purchasers under this Agreement are subject to the fulfillment or waiver, on or before the Closing, of each
of the following conditions:


(a)              
Representations and Warranties True. The representations and warranties of the Purchasers contained in Section 4 shall be
true and correct in all material respects on and as of the date hereof (provided, however, that such materiality qualification
shall only apply to representations and warranties not otherwise qualified by materiality) and on and as of the date of the Closing
with the same effect as though such representations and warranties had been made as of the Closing.



    	14



    	 



    




(b)              
Performance. The Purchasers shall have performed and complied in all material respects with all agreements, obligations and
conditions contained in this Agreement that are required to be performed or complied with by the Purchasers on or before the Closing
and shall have obtained all approvals, consents and qualifications necessary to complete the purchase and sale described herein.


(c)               
Agreement. The Purchasers shall have executed and delivered to the Company this Agreement (and Appendix I hereto).


(d)              
Securities Exemptions. The offer and sale of the Shares to the Purchasers pursuant to this Agreement shall be exempt from
the registration requirements of the Securities Act and the registration and/or qualification requirements of all applicable state
securities laws.


(e)               
Payment of Purchase Price. The Purchasers shall have delivered to the Company by wire transfer of immediately available funds,
full payment of the purchase price for the Shares as specified in Section 1(b).


(f)               
No Statute or Rule Challenging Transaction. No statute, rule, regulation, executive order, decree, ruling, injunction, action,
proceeding or interpretation shall have been enacted, entered, promulgated, endorsed or adopted by any court or governmental authority
of competent jurisdiction or any self-regulatory organization or the staff of any of the foregoing, having authority over the
matters contemplated hereby that questions the validity of, or challenges or prohibits the consummation of, any of the transactions
contemplated by this Agreement.





7.                 
Miscellaneous.


(a)              
Successors and Assigns. The terms and conditions of this Agreement will inure to the benefit of and be binding upon the respective
successors and permitted assigns of the parties. The Company shall not assign this Agreement or any rights or obligations hereunder
without the prior written consent of the Purchasers holding a majority of the total aggregate number of Shares then outstanding
(excluding any shares sold to the public pursuant to Rule 144 or otherwise). A Purchaser may assign its rights under this Agreement
to any person to whom the Purchaser assigns or transfers any Shares, provided that such transferee agrees in writing to be bound
by the terms and provisions of this Agreement, and such transfer is in compliance with the terms and provisions of this Agreement
and permitted by federal and state securities laws.


(b)              
Governing Law. This Agreement will be governed by and construed and enforced under the internal laws of the State of Florida,
without reference to principles of conflict of laws or choice of laws.


(c)               
Survival. The representations and warranties of the Company and the Purchasers contained in Sections 3 and 4 of this Agreement
shall survive until the second anniversary of the Closing Date.



    	15



    	 



    




(d)              
Counterparts. This Agreement may be executed in two or more counterparts, each of which will be deemed an original, but all
of which together will constitute one and the same instrument.


(e)               
Headings. The headings and captions used in this Agreement are used for convenience only and are not to be considered in construing
or interpreting this Agreement. All references in this Agreement to sections, paragraphs, exhibits and schedules will, unless
otherwise provided, refer to sections and paragraphs hereof and exhibits and schedules attached hereto, all of which exhibits
and schedules are incorporated herein by reference.


(f)               
Notices. Any notices and other communications required or permitted under this Agreement shall be in writing and shall be
delivered (i) personally by hand or by courier, (ii) mailed by United States first-class mail, postage prepaid or (iii) sent by
facsimile directed (A) if to a Purchaser, at such Purchaser’s address or facsimile number set forth on such Purchaser’s
signature page to this Agreement, or at such address or facsimile number as such Purchaser may designate by giving at least ten
days’ advance written notice to the Company or (B) if to the Company, to its address or facsimile number set forth below,
or at such other address or facsimile number as the Company may designate by giving at least ten days’ advance written notice
to the Purchaser. All such notices and other communications shall be deemed given upon (I) receipt or refusal of receipt, if delivered
personally, (II) three days after being placed in the mail, if mailed, or (III) confirmation of facsimile transfer, if faxed.


The
address of the Company for the purpose of this Section 7(f) is as follows:


MedeFile
International, Inc.


301
Yamato Road, Suite 1200


Boca
Raton, FL 33431


Tel:
(561) 912-3393


Fax:
(561) 912-3396


Attention:
Niquana Noel


 


with
a copy to:


 


Sichenzia
Ross Friedman Ference LLP


61
Broadway


New
York, NY 10018


Tel:
(212) 930-9700


Fax:
(212) 930-9725


Attention:
Richard A. Friedman, Esq.


 


(g)              
Amendments and Waivers. This Agreement may be amended and the observance of any term of this Agreement may be waived only
with the written consent of the Company and the Purchasers holding a majority of the total aggregate number of Shares then outstanding
(excluding any shares sold to the public pursuant to Rule 144 or otherwise). Any amendment effected in accordance with this Section
7(g) will be binding upon the Purchasers, the Company and their respective successors and permitted assigns.



    	16



    	 



    




(h)              
Severability. If any provision of this Agreement is held to be unenforceable under applicable law, such provision will be
excluded from this Agreement and the balance of the Agreement will be interpreted as if such provision were so excluded and will
be enforceable in accordance with its terms.


(i)                
Entire Agreement. This Agreement, together with all exhibits and schedules hereto and thereto, constitutes the entire agreement
and understanding of the parties with respect to the subject matter hereof and supersedes any and all prior negotiations, correspondence,
agreements, understandings, duties or obligations between the parties with respect to the subject matter hereof.


(j)                
No Additional Agreements. The Company does not have any written or oral contract, agreement, arrangement or understanding
with any Purchaser with respect to the transactions contemplated by this Agreement other than as expressly stated herein.


(k)              
Further Assurances. From and after the date of this Agreement, upon the request of the Company or the Purchasers, the Company
and the Purchasers will execute and deliver such instruments, documents or other writings, and take such other actions, as may
be reasonably necessary or desirable to confirm and carry out and to effectuate fully the intent and purposes of this Agreement.


(l)                
Meaning of Include and Including. Whenever in this Agreement the word “include” or “including” is
used, it shall be deemed to mean “include, without limitation” or “including, without limitation,” as
the case may be, and the language following “include” or “including” shall not be deemed to set forth
an exhaustive list.


(m)            
Fees, Costs and Expenses. All fees, costs and expenses (including attorneys’ fees and expenses) incurred by any party
hereto in connection with the preparation, negotiation and execution of this Agreement and the exhibits and schedules hereto and
the consummation of the transactions contemplated hereby and thereby shall be the sole and exclusive responsibility of such party.
In addition, the Company will pay the costs associated with any filings with, or compliance with any of the requirements of any
governmental authorities.


(n)              
Remedies. In addition to being entitled to exercise all rights provided herein or granted by law, including recovery of damages,
each Purchaser and the Company will be entitled to specific performance under this Agreement. The parties agree that monetary
damages may not be adequate compensation for any loss incurred by reason of any breach of obligations described in the foregoing
sentence and hereby agrees to waive in any action for specific performance of any such obligation the defense that a remedy at
law would be adequate.


(q)Several
Liability; Advice. Each Purchaser agrees that no other Purchaser nor the respective controlling persons, officers, directors,
partners, agents or employees of any other Purchaser shall be liable to such Purchaser for any losses incurred by such Purchaser
in connection with its investment in the Company. Each Purchaser acknowledges that it is not relying upon any person, firm or
corporation (including without limitation any other Purchaser), other than the Company and its officers and directors (acting
in their capacity as representatives of the Company), in deciding to invest and in making its investment in the Company. The Company
acknowledges that no Purchaser is acting or has acted as an advisor, agent or fiduciary of the Company (or in any similar capacity)
with respect to this Agreement and any advice given by any Purchaser or any of its representatives in connection with this Agreement
is merely incidental to the Purchasers’ purchase of securities of the Company hereunder.


 



    	17



    	 



    






 





The
parties hereto have executed this Agreement as of the date and year first above written.








 


	 	MedeFile
International, Inc.
	 	 
	 	By: 	/s/ Niquana
Noel
	 	 	Niquana
Noel
Chief
Executive Officer



 


 


 


[PURCHASER
SIGNATURE PAGES TO FOLLOW]


 









    	18



    	 



    

 


 


SIGNATURE
PAGE TO



SECURITIES PURCHASE AGREEMENT



DATED AS OF _______, 2015



BY AND AMONG



MEDEFILE INTERNATIONAL, INC.



AND EACH PURCHASER NAMED THEREIN


The
undersigned hereby executes and delivers to MedeFile International, Inc., the Securities Purchase Agreement (the “Agreement”)
to which this signature page is attached, which Agreement and signature page, together with all counterparts of such Agreement
and signature pages of the other Purchasers named in such Agreement, shall constitute one and the same document in accordance
with the terms of such Agreement.





	 	Number of Shares:	 
	 	 	 
	 	Name of
    Purchaser	 
	 	 	 
	 	Signature:	 
	 	 	 
	 	By:	 
	 	 	 
	 	Title:	 
	 	 	 
	 	Address:	 
	 	 	 
	 		 
			 
	 	 	 
	 	Telephone:	 
	 	 	 
	 	Fax:	 
	 		 
	 	Tax ID Number:	 



 









    	19



    	 



    

 


Appendix
I


STOCK
CERTIFICATE QUESTIONNAIRE


Please
provide us with the following information:


	1.The
    exact name that the Shares are to be registered in (this is the name that will appear on the stock certificate(s)). You may
    use a nominee name if appropriate:	
	2.The
    relationship between the Purchaser of the Shares and the Registered Holder listed in response to item 1 above:	
	3.The
    mailing address of the Registered Holder listed in response to item 1 above:	

	4.The
    Tax Identification Number of the Registered Holder listed in response to item 1 above:	



 


 





2020