EX-4.1



 Exhibit 4.1 

EXECUTION VERSION 
 HORIZON
PHARMA INVESTMENT LIMITED, as Issuer 
 HORIZON PHARMA PUBLIC LIMITED COMPANY, as Guarantor 

AND 
 U.S. BANK NATIONAL
ASSOCIATION, as Trustee 
  
  

Indenture 
 Dated as of
March 13, 2015 
 2.50% Exchangeable Senior Notes due 2022 
  

 







 Table of Contents 

 

							
	 		 		Page  	 
		
	 ARTICLE 1         DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION
		 	1	  
			
	 Section 1.01
		 Definitions
		 	1	  
			
	 Section 1.02
		 References to Interest
		 	16	  
			
	 Section 1.03
		 Compliance Certificates and Opinions
		 	16	  
			
	 Section 1.04
		 Form of Documents Delivered to Trustee
		 	16	  
			
	 Section 1.05
		 Acts of Holders; Record Dates
		 	17	  
			
	 Section 1.06
		 Notices, Etc., to Trustee and the Issuer
		 	18	  
			
	 Section 1.07
		 Notice to Holders; Waiver
		 	18	  
		
	 ARTICLE 2         SECURITY FORMS
		 	19	  
			
	 Section 2.01
		 Forms Generally
		 	19	  
			
	 Section 2.02
		 Form of Face of Note
		 	19	  
			
	 Section 2.03
		 Form of Reverse of Note
		 	24	  
		
	 ARTICLE 3         THE SECURITIES
		 	31	  
			
	 Section 3.01
		 Title and Terms; Payments
		 	31	  
			
	 Section 3.02
		 Denominations
		 	32	  
			
	 Section 3.03
		 Execution, Authentication, Delivery and Dating
		 	32	  
			
	 Section 3.04
		 Temporary Notes
		 	32	  
			
	 Section 3.05
		 Registration; Registration of Transfer and Exchange
		 	33	  
			
	 Section 3.06
		 Transfer Restrictions
		 	34	  
			
	 Section 3.07
		 Expiration of Restrictions
		 	36	  
			
	 Section 3.08
		 Mutilated, Destroyed, Lost and Stolen Notes
		 	37	  
			
	 Section 3.09
		 Persons Deemed Owners
		 	38	  
			
	 Section 3.10
		 Transfer and Exchange
		 	38	  
			
	 Section 3.11
		 Cancellation
		 	41	  
			
	 Section 3.12
		 CUSIP Numbers
		 	42	  
			
	 Section 3.13
		 Payment and Computation of Interest
		 	42	  
			
	 Section 3.14
		 Business Day
		 	42	  
		
	 ARTICLE 4         PARTICULAR COVENANTS OF THE ISSUER
		 	42	  
			
	 Section 4.01
		 Payment of Principal and Interest
		 	42	  
			
	 Section 4.02
		 Maintenance of Office or Agency
		 	43	  
			
	 Section 4.03
		 Appointments to Fill Vacancies in Trustee’s Office
		 	43	  
			
	 Section 4.04
		 Provisions as to Paying Agent
		 	44	  
			
	 Section 4.05
		 Existence
		 	45	  
			
	 Section 4.06
		 Additional Interest
		 	45	  


  
 ii 









							
			
	 Section 4.07
		 Rule 144A Information Requirement and Annual Reports
		 	46	  
			
	 Section 4.08
		 Stay; Extension and Usury Laws
		 	47	  
			
	 Section 4.09
		 Compliance Certificate
		 	47	  
			
	 Section 4.10
		 Additional Amounts
		 	47	  
			
	 Section 4.11
		 Listing of the Notes
		 	50	  
		
	 ARTICLE 5         REDEMPTION
		 	51	  
			
	 Section 5.01
		 Optional Redemption
		 	51	  
			
	 Section 5.02
		 Notice of Tax Redemption and Notice of Provisional Redemption
		 	52	  
			
	 Section 5.03
		 Holder’s Right to Elect in Connection with a Tax Redemption
		 	54	  
			
	 Section 5.04
		 Effect of Notice of Tax Redemption and Notice of Provisional Redemption
		 	55	  
			
	 Section 5.05
		 Deposit of Redemption Price
		 	55	  
			
	 Section 5.06
		 Notes Redeemed in Part
		 	56	  
		
	 ARTICLE 6         [RESERVED]
		 	56	  
		
	 ARTICLE 7         EXCHANGE
		 	56	  
			
	 Section 7.01
		 Right to Exchange
		 	56	  
			
	 Section 7.02
		 Exchange Procedures
		 	59	  
			
	 Section 7.03
		 Settlement Upon Exchange
		 	62	  
			
	 Section 7.04
		 Certain Provisions Related to Ordinary Shares Issued Hereunder
		 	66	  
			
	 Section 7.05
		 Adjustment of Exchange Rate
		 	66	  
			
	 Section 7.06
		Adjustments to Exchange Rate upon Exchange In Connection With a Make-Whole Fundamental Change or a Tax Redemption		 	79	  
			
	 Section 7.07
		 Effect of Recapitalization, Reclassification, Consolidation, Merger or Sale
		 	82	  
			
	 Section 7.08
		 No Responsibility of Trustee
		 	84	  
		
	 ARTICLE 8         PURCHASE AT OPTION OF HOLDERS UPON A FUNDAMENTAL CHANGE
		 	84	  
			
	 Section 8.01
		 Fundamental Change Permits Holders to Require the Issuer to Repurchase the Notes
		 	84	  
			
	 Section 8.02
		 Fundamental Change Notice
		 	85	  
			
	 Section 8.03
		 Fundamental Change Repurchase Notice
		 	86	  
			
	 Section 8.04
		 Withdrawal of Fundamental Change Repurchase Notice
		 	87	  
			
	 Section 8.05
		 Effect of Fundamental Change Repurchase Notice
		 	88	  
			
	 Section 8.06
		 Notes Repurchased in Whole or in Part
		 	88	  
			
	 Section 8.07
		 Covenant to Comply with Securities Laws upon Repurchase of Notes
		 	89	  
			
	 Section 8.08
		 Deposit Fundamental Change Repurchase Price
		 	89	  
			
	 Section 8.09
		 Covenant Not to Repurchase Notes upon Certain Events of Default
		 	89	  
		
	 ARTICLE 9         EVENTS OF DEFAULT; REMEDIES
		 	90	  
			
	 Section 9.01
		 Events of Default
		 	90	  
			
	 Section 9.02
		 Acceleration
		 	92	  
			
	 Section 9.03
		 Other Remedies
		 	92	  


  
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	 Section 9.04
		 Sole Remedy for Failure to Report
		 	93	  
			
	 Section 9.05
		 [Reserved]
		 	94	  
			
	 Section 9.06
		 Control By Majority
		 	94	  
			
	 Section 9.07
		 Limitation on Suits
		 	94	  
			
	 Section 9.08
		 Rights of Holders to Receive Payment and to Exchange
		 	95	  
			
	 Section 9.09
		 Collection Suit by Trustee
		 	95	  
			
	 Section 9.10
		 Trustee May Enforce Claims Without Possession of Notes
		 	95	  
			
	 Section 9.11
		 Trustee May File Proofs of Claim
		 	95	  
			
	 Section 9.12
		 Restoration of Rights and Remedies
		 	96	  
			
	 Section 9.13
		 Rights and Remedies Cumulative
		 	96	  
			
	 Section 9.14
		 Delay or Omission Not a Waiver
		 	96	  
			
	 Section 9.15
		 Priorities
		 	96	  
			
	 Section 9.16
		 Undertaking for Costs
		 	97	  
		
	ARTICLE 10         CONSOLIDATION, MERGER, AMALGAMATION OR SALE OF ASSETS AND TAX RESIDENCE		 	97	  
			
	 Section 10.01
		 Issuer and Guarantor May Consolidate on Certain Terms
		 	97	  
			
	 Section 10.02
		 Successor to Be Substituted
		 	98	  
			
	 Section 10.03
		 Change of Tax Residence
		 	98	  
		
	 ARTICLE 11         THE TRUSTEE
		 	98	  
			
	 Section 11.01
		 Duties and Responsibilities of Trustee
		 	98	  
			
	 Section 11.02
		 Notice of Defaults
		 	100	  
			
	 Section 11.03
		 Reliance on Documents, Opinions, Etc.
		 	100	  
			
	 Section 11.04
		 No Responsibility for Recitals, Etc.
		 	101	  
			
	 Section 11.05
		 Trustee, Paying Agents, Exchange Agents or Registrar May Own Notes
		 	101	  
			
	 Section 11.06
		 Monies to be Held in Trust
		 	101	  
			
	 Section 11.07
		 Compensation and Expenses of Trustee
		 	102	  
			
	 Section 11.08
		 Officer’s Certificate as Evidence
		 	102	  
			
	 Section 11.09
		 Conflicting Interests of Trustee
		 	102	  
			
	 Section 11.10
		 Eligibility of Trustee
		 	103	  
			
	 Section 11.11
		 Resignation or Removal of Trustee
		 	103	  
			
	 Section 11.12
		 Acceptance by Successor Trustee
		 	104	  
			
	 Section 11.13
		 Succession by Merger, Etc.
		 	105	  
			
	 Section 11.14
		 Preferential Collection of Claims
		 	105	  
			
	 Section 11.15
		 Trustee’s Application for Instructions from the Issuer
		 	105	  
		
	 ARTICLE 12         HOLDERS’ LISTS AND REPORTS BY TRUSTEE
		 	106	  
			
	 Section 12.01
		 Issuer to Furnish Trustee Names and Addresses of Holders
		 	106	  
			
	 Section 12.02
		 Preservation of Information; Communications to Holders
		 	106	  


  
 iv 









							
			
	 Section 12.03
		 Reports By Trustee
		 	106	  
		
	ARTICLE 13         SATISFACTION AND DISCHARGE		 	107	  
			
	 Section 13.01
		 Discharge of Liability on Notes
		 	107	  
			
	 Section 13.02
		 Deposited Moneys to Be Held in Trust
		 	107	  
			
	 Section 13.03
		 Paying Agent to Repay Monies Held
		 	107	  
			
	 Section 13.04
		 Repayment to the Issuer
		 	107	  
			
	 Section 13.05
		 Reinstatement
		 	107	  
		
	ARTICLE 14         SUPPLEMENTAL INDENTURES		 	108	  
			
	 Section 14.01
		 Without Consent of Holders
		 	108	  
			
	 Section 14.02
		 With Consent of Holders
		 	109	  
			
	 Section 14.03
		 Notices of Supplemental Indentures
		 	110	  
			
	 Section 14.04
		 Execution of Supplemental Indentures
		 	110	  
		
	ARTICLE 15         GUARANTEE		 	110	  
			
	 Section 15.01
		 Guarantee
		 	110	  
			
	 Section 15.02
		 Limitation of Guarantor’s Liability; Certain Bankruptcy Events
		 	112	  
			
	 Section 15.03
		 Application of Certain Terms and Provisions to the Guarantor
		 	112	  
		
	ARTICLE 16         MISCELLANEOUS		 	113	  
			
	 Section 16.01
		 Official Acts by Successor Corporation
		 	113	  
			
	 Section 16.02
		 Notices
		 	113	  
			
	 Section 16.03
		 Rules by Trustee, Paying Agent and Registrar
		 	114	  
			
	 Section 16.04
		 Governing Law
		 	114	  
			
	 Section 16.05
		 No Recourse against Others
		 	115	  
			
	 Section 16.06
		 Successors
		 	115	  
			
	 Section 16.07
		 Multiple Originals
		 	115	  
			
	 Section 16.08
		 Benefits of Indenture
		 	115	  
			
	 Section 16.09
		 Table of Contents; Headings
		 	115	  
			
	 Section 16.10
		 Severability Clause
		 	115	  
			
	 Section 16.11
		 Calculations
		 	115	  
			
	 Section 16.12
		 Waiver of Jury Trial
		 	115	  
			
	 Section 16.13
		 Consent to Jurisdiction
		 	116	  
			
	 Section 16.14
		 Judgment Currency
		 	116	  
			
	 Section 16.15
		 Force Majeure
		 	116	  
			
	 Section 16.16
		 U.S.A. Patriot Act
		 	117	  


  
 v 








 INDENTURE, dated as of March 13, 2015 by and among Horizon Pharma Investment Limited, a
Bermuda exempted company limited by shares, as Issuer (as more fully set forth in Section 1.01, the “Issuer”), Horizon Pharma Public Limited Company, a public limited company formed under the laws of Ireland, as Guarantor (as more
fully set forth in Section 1.01, the “Guarantor”), and U.S. Bank National Association, a national banking association, as Trustee (as more fully set forth in Section 1.01, the “Trustee”). 

RECITALS OF THE ISSUER 

WHEREAS, the Issuer has duly authorized the creation of an issue of 2.50% Exchangeable Senior Notes due 2022 (each a “Note”
and collectively, the “Notes”) guaranteed on a senior unsecured basis by the Guarantor of the tenor and amount hereinafter set forth, and to provide therefor the Issuer has duly authorized the execution and delivery of this
Indenture and the Guarantor has duly authorized the execution and delivery of this Indenture and issuance of the Guarantee of the Notes (as more fully set forth in Section 1.01, the “Guarantee”); and 

WHEREAS, all things necessary to make the Notes and the Guarantee, when the Notes are executed by the Issuer and this Indenture is executed by
the Issuer and the Guarantor, respectively, and authenticated and delivered hereunder and duly issued by the Issuer and the Guarantor, respectively, the valid and legally binding obligations of the Issuer and the Guarantor, respectively, and to make
this Indenture a valid and legally binding agreement of the Issuer and the Guarantor, in accordance with the terms of the Notes; the Guarantee and the Indenture, have been done. 

NOW, THEREFORE, THIS INDENTURE WITNESSETH, for and in consideration of the premises and the purchases of the Notes and the Guarantee by the
Holders thereof, it is mutually agreed, for the benefit of the Issuer and the equal and proportionate benefit of all Holders of the Notes and the Guarantee, as follows: 

ARTICLE 1 
 DEFINITIONS AND OTHER
PROVISIONS OF GENERAL APPLICATION 
 Section 1.01   Definitions. For all purposes of this Indenture, except as
otherwise expressly provided or unless the context otherwise requires: 
 (a)     the terms defined in
this Article 1 have the meanings assigned to them in this Article and include the plural as well as the singular; 
 (b)
    all accounting terms not otherwise defined herein have the meanings assigned to them in accordance with GAAP; and 

(c)     the words “herein,” “hereof’ and “hereunder” and other words of
similar import refer to this Indenture as a whole and not to any particular Article, Section or other subdivision. 
 “Act”
when used with respect to any Holder, has the meaning specified in Section 1.05. 
 “Additional Amounts” has the meaning
specified in Section 4.10. 

  
 1 








 “Additional Interest” means all amounts, if any, payable pursuant to Section
4.06 and Section 9.04 hereof. Unless the context otherwise requires, all references in this Indenture to interest include Additional Interest, if any. Any express reference to Additional Interest in this Indenture shall not be construed as excluding
Additional Interest in any other text where no such express reference is made. 
 “Additional Notes” means any Notes (other
than the Initial Notes) issued under this Indenture in accordance with Section 3.01 hereof. 
 “Additional Shares” has the
meaning specified in Section 7.06(a). 
 “Affiliate” of any specified Person means any other Person directly or indirectly
controlling or controlled by or under direct or indirect common control with such specified Person. For the purposes of this definition, “control,” when used with respect to any specified Person means the power to direct or cause the
direction of the management and policies of such Person, directly or indirectly, whether through the ownership of voting securities, by contract or otherwise; and the terms “controlling” and “controlled” have meanings correlative
to the foregoing. 
 “Agent Members” has the meaning specified in Section 3.05(b). 

“applicable Exchange Price” means the Exchange Price in effect at any given time. 

“applicable Exchange Rate” means the Exchange Rate in effect at any given time. 

“Applicable Procedures” means, with respect to any transfer or transaction involving a Global Note or any beneficial interest
therein, the rules and procedures of the Depositary for such Note, in each case to the extent applicable to such transfer or transaction and as in effect from time to time. 

“Applicable Taxes” has the meaning specified in Section 4.10. 

“Bankruptcy Law” means Title 11 of the United States Code (or any successor thereto) or any similar bankruptcy, insolvency or
other U.S. federal or state law, or equivalent foreign law (including Irish or Bermuda law), for the relief of debtors, whether now or hereafter in effect. 

“Benefited Party” has the meaning specified in Section 15.01. 

“Bid Solicitation Agent” means the Issuer or the Person appointed by the Issuer to solicit bids for the Trading Price of the
Notes in accordance with Section 7.01(b). The Issuer shall initially act as the Bid Solicitation Agent. 
 “Board of
Directors” means either the Board of Directors of the Issuer or any duly authorized committee of that board. 

  
 2 








 “Board Resolution” means a copy of a resolution certified by the Secretary or a
Director of the Board of Directors of the Issuer to have been duly adopted by the Board of Directors and to be in full force and effect on the date of such certification, and delivered to the Trustee. 

“Business Day” means any day other than a Saturday, a Sunday or a day on which the Federal Reserve Bank of New York is
authorized or required by law or executive order to close or be closed. 
 “Cash Settlement” has the meaning specified in
Section 7.03(a). 
 “Change in Tax Law” has the meaning specified in Section 5.01(a). 

“Clause A Distribution” has the meaning specified in Section 7.05(c). 

“Clause B Distribution” has the meaning specified in Section 7.05(c). 

“Clause C Distribution” has the meaning specified in Section 7.05(c). 

“Close of Business” means 5:00 p.m. New York City time. 

“Code” means the Internal Revenue Code of 1986, as amended. 

“Combination Settlement” has the meaning specified in Section 7.03(a). 

“Commission” means the U.S. Securities and Exchange Commission, as from time to time constituted, created under the Exchange
Act. 
 “Company Order” means a written request or order signed in the name of the Issuer by any Officer, and delivered to
the Trustee. 
 “Corporate Trust Office” means the office of the Trustee at which the corporate trust business of the
Trustee shall, at any particular time, be principally administered, which office is, at the date as of which this Indenture is dated, located at U.S. Bank National Association, Global Corporate Trust Services, Mailcode: EP-MN-WS3C, 60 Livingston
Avenue, St. Paul, Minnesota 55107-2292; Attention: Rick Prokosch – Horizon Pharma Corporate Trust Administrator, or such other address in the United States as the Trustee may designate from time to time by notice to the Holders and the Issuer,
or the principal corporate trust office in the United States of any successor Trustee (or such other address in the United States as such successor Trustee may designate from time to time by notice to the Holders and the Issuer). 

“Custodian” means any receiver, examiner, trustee, assignee, liquidator, custodian or similar official under any Bankruptcy
Law. 
 “Daily Exchange Value” means, for any of the 40 consecutive VWAP Trading Days during an Observation Period, 2.5% of
the product of (i) the Exchange Rate on such VWAP Trading Day and (ii) the Daily VWAP on such VWAP Trading Day. 
 “Daily
Measurement Value” means the Specified Dollar Amount (if any) divided by 40. 

  
 3 








 “Daily Settlement Amount” for any of the 40 consecutive VWAP Trading Days during
an Observation Period, shall consist of: 
 (1)         cash equal to the lesser of
(a) the Daily Measurement Value for such Observation Period and (b) the Daily Exchange Value for such VWAP Trading Day; and 

(2)         if the Daily Exchange Value for such VWAP Trading Day exceeds the Daily
Measurement Value for such Observation Period, the Daily Share Amount for such VWAP Trading Day. 
 “Daily Share Amount”
means, for any of the 40 consecutive VWAP Trading Days during an Observation Period on which the Daily Exchange Value exceeds the Daily Measurement Value, the amount equal to (i) the difference between the Daily Exchange Value for such VWAP
Trading Day and the Daily Measurement Value for such VWAP Trading Day, divided by (ii) the Daily VWAP for such VWAP Trading Day. 

“Daily VWAP” means, for any of the 40 consecutive VWAP Trading Days during an Observation Period, the per Ordinary Share
volume-weighted average price as displayed under the heading “Bloomberg VWAP” on Bloomberg page HZNP<equity>AQR (or its equivalent successor if such page is not available) in respect of the period from the scheduled open of trading
until the scheduled close of trading of the primary trading session on such VWAP Trading Day (or if such volume-weighted average price is unavailable, the market value of one Ordinary Share on such VWAP Trading Day, determined, using a
volume-weighted average method, by a nationally recognized independent investment banking firm retained for this purpose by the Issuer). The Daily VWAP will be determined without regard to after hours trading or any other trading outside of the
regular trading session trading hours. 
 “Default” means any event that is, or with the passage of time or the giving of
notice or both would be, an Event of Default. 
 “Depositary” means DTC until a successor Depositary shall have become such
pursuant to the applicable provisions of this Indenture, and thereafter “Depositary” shall mean such successor Depositary. 

“Distributed Property” has the meaning specified in Section 7.05(c). 

“DTC” means The Depository Trust Company. 

“Effective Date” means the first date on which the Ordinary Shares trade on the applicable exchange or in the applicable
market, regular way, reflecting the relevant share subdivision or share consolidation, as applicable. 
 “Event of Default”
has the meaning specified in Section 9.01. 
 “Ex-Dividend Date” means the first date on which the Ordinary Shares trade on
the applicable exchange or in the applicable market, regular way, without the right to receive the 

  
 4 








 
issuance, dividend or distribution in question, from the Guarantor or, if applicable, from the seller of the Ordinary Shares on such exchange or market (in the form of due bills or otherwise) as
determined by such exchange or market. 
 “Exchange Act” means the U.S. Securities Exchange Act of 1934, as amended. 

“Exchange Agent” initially means the Trustee or such other office or agency designated by the Issuer where Notes may be
presented for exchange. 
 “Exchange Consideration” has the meaning specified in Section 7.03(c). 

“Exchange Date” has the meaning specified in Section 7.02(a). 

“Exchange Notice” has the meaning specified in Section 7.02(a). 

“Exchange Obligation” has the meaning specified in Section 7.03(a). 

“Exchange Price” means, per Ordinary Share, $1,000 divided by the applicable Exchange Rate. 

“Exchange Rate” means initially 34.8979 Ordinary Shares per $1,000 principal amount of Notes, subject to adjustment as set
forth herein. 
 “Excluded Holder” has the meaning specified in Section 5.03(b). 

“Financial Institution Surrender” has the meaning specified in Section 7.03(c). 

“Financial Institution Surrender Election” has the meaning specified in Section 7.03(c). 

“Freely Tradable” means, with respect to any Notes and any proposed transfer thereof, that such Notes are eligible for sale
and transfer without registration under the Securities Act pursuant to Rule 144 (without being subject to limitations on volume or manner of sale pursuant to Rule 144) by Holders, other than affiliates of the Issuer or the Guarantor (within the
meaning of Rule 144) or Holders that were affiliates of the Issuer or the Guarantor (within the meaning of Rule 144) during the three months immediately preceding the proposed transfer (as a result of restrictions imposed by U.S. federal securities
laws or the terms of this Indenture or the Notes). 
 “Free Trade Date” means the date that is one year after the last date
of original issuance of the Initial Notes under this Indenture. 
 “Fundamental Change” shall be deemed to have occurred at
the time after the Issue Date of the Notes if any of the following occurs: 
 (1)
        any “person” or “group” (within the meaning of Section 13(d) of the Exchange Act), other than the Guarantor or its Wholly Owned Subsidiaries or its or their employee benefit
plans, files a Schedule TO or any schedule, form or report under the 

  
 5 








 
Exchange Act disclosing that such person or group has become the direct or indirect “beneficial owner,” as defined in Rule 13d-3 under the Exchange Act, of the Guarantor’s Ordinary
Share Capital representing more than 50% of the voting power of the Guarantor’s issued Ordinary Share Capital; 
 (2)
        the consummation of (A) any recapitalization, reclassification or change of the Ordinary Shares (other than changes resulting from a subdivision or consolidation or any recapitalization,
reclassification or change of our common stock pursuant to a transaction described in Clause (B) below) as a result of which the Ordinary Shares would be converted into, or exchanged for, shares, other securities, or other property or assets;
(B) any share exchange, consolidation or merger of, or scheme of arrangement involving, the Guarantor pursuant to which the Ordinary Shares will be converted into, or exchanged for, cash, securities or other property or assets; or (C) any
sale, lease or other transfer in one transaction or a series of transactions of all or substantially all of the consolidated assets of the Guarantor and its Subsidiaries, taken as a whole, to any Person other than one of the Guarantor’s direct
or indirect Wholly Owned Subsidiaries; provided, however, that a transaction described in clause (B) in which the holders of all classes of the Ordinary Share Capital or common equity of the Guarantor immediately prior to such
transaction own, directly or indirectly, more than 50% of all classes of the issued Ordinary Share Capital or common equity of the continuing or surviving person or transferee or the parent thereof immediately after such transaction in substantially
the same proportions (relative to each other) as such ownership immediately prior to such transaction shall not be a Fundamental Change pursuant to this clause (2); 

(3)         the Guarantor’s shareholders approve any plan or proposal for the
liquidation or dissolution of the Guarantor (other than in a transaction described in clause (2) above); or 
 (4)
        the Ordinary Shares (or other Ordinary Share Capital or common equity interests (or depositary receipts) underlying the Notes based on which the Notes are then exchangeable pursuant to the terms of the
Indenture) cease to be listed on any of The New York Stock Exchange, The NASDAQ Global Market, The NASDAQ Capital Market or The NASDAQ Global Select Market (or any of their respective successors); 

provided, however, that in the case of an event, transaction or series of related transactions described in clause (1) or (2) above,
if at least 90% of the consideration received or to be received by holders of the Ordinary Shares (excluding cash payments for fractional ordinary 

  
 6 








 
shares or dissenter’s rights) in the event, transaction or transactions that would otherwise constitute a Fundamental Change consists of Publicly Traded Securities, and as a result of such
event, transaction or transactions, the Notes become exchangeable based on such consideration, excluding cash payments for fractional ordinary shares or dissenter’s rights (subject to settlement in accordance with the provisions of Sections
7.03, 7.05 and 7.06), such event, transaction or transactions shall not be a “Fundamental Change;” provided further that, for purposes of this definition, any transaction or event that constitutes a Fundamental Change pursuant to
both clause (1) and clause (2) above shall be deemed a Fundamental Change solely under clause (2) above. 
 Further, if any transaction
occurs in which Guarantor becomes a Wholly Owned Subsidiary of another entity and the Ordinary Shares are converted into, or exchanged for, Reference Property consisting of Ordinary Shares or other Ordinary Share Capital or common equity interests
(or depository receipts representing Ordinary Share Capital or common equity interests) of such other entity, following the completion of any related Make-Whole Fundamental Change Period, any references to the Guarantor in this definition shall
instead be references to such other entity. 
 “Fundamental Change Notice” has the meaning specified in Section 8.02(a).

 “Fundamental Change Notice Date” has the meaning specified in Section 8.02(a). 

“Fundamental Change Repurchase Date” has the meaning specified in Section 8.01(c). 

“Fundamental Change Repurchase Notice” has the meaning specified in Section 8.03(a)(i). 

“Fundamental Change Repurchase Price” has the meaning specified in Section 8.01(b). 

“GAAP” means generally accepted accounting principles set forth in the opinions and pronouncements of the Accounting
Principles Board of the American Institute of Certified Public Accountants and statements and pronouncements of the Financial Accounting Standards Board or in such other statements by such other entity as have been approved by a significant segment
of the accounting profession, in each case, as in effect in the United States from time to time. 
 “Global Note” means a
Note in global form registered in the Register in the name of a Depositary or a nominee thereof. 
 “Guarantee” means the
full and unconditional guarantee provided by the Guarantor in respect of the Notes as made applicable to the Notes in accordance with the provisions of Section 15.01 hereof. 

“Guarantee Obligations” has the meaning specified in Section 15.01. 

“Guarantor” means the corporation named as the “Guarantor” in the first paragraph of this Indenture, and, subject
to the provisions of Article 10 and Section 7.07, shall include its successors and assigns. 

  
 7 








 “Guarantor’s Board of Directors” means either the Board of Directors of the
Guarantor or any duly authorized committee of that board. 
 “Holder” means a Person in whose name a Note is registered in
the Register. 
 “Indenture” means this instrument as originally executed or as it may from time to time be supplemented or
amended by one or more indentures supplemental hereto entered into pursuant to the applicable provisions hereof, including, for all purposes of this instrument and any such supplemental indenture. 

“Initial Notes” has the meaning specified in Section 3.01. 

“Initial Purchasers” means the initial purchasers listed in the pricing term sheet, dated March 5, 2015, related to the
offer and sale of the Initial Notes. 
 “Interest Payment Date” means each March 15 and September 15 of each
year, beginning September 15, 2015. 
 “Issue Date” means March 13, 2015. 

“Issuer” means the Person named as the “Issuer” in the first paragraph of this instrument and, subject to the
provisions of Article 10 and Section 7.07, shall include its successors and assigns. 
 “Last Reported Sale Price” means,
for the Ordinary Shares (or any other security for which a Last Reported Sale Price must be determined), on any Trading Day, the closing sale price per Ordinary Share (or such other security, as the case may be) (or if no closing sale price is
reported, the average of the bid and ask prices or, if more than one in either case, the average of the average bid and the average ask prices) on that date as reported in composite transactions for the principal U.S. securities exchange on which
the Ordinary Shares (or such other security as the case may be) are listed. If the Ordinary Shares (or such other security, as the case may be) are not listed for trading on a U.S. national or regional securities exchange on the relevant date, the
“Last Reported Sale Price” of the Ordinary Shares (or such other security, as the case may be) will be the last quoted bid price for the Ordinary Shares (or such other security, as the case may be) in the over-the-counter market on the
relevant date as reported by OTC Markets Group Inc. or a similar organization. If the Ordinary Shares (or such other security, as the case may be) are not so quoted, the “Last Reported Sale Price” will be the average of the mid-point of
the last bid and ask prices for the Ordinary Shares (or such other security, as the case may be) on the relevant date from each of at least three nationally recognized independent investment banking firms selected by the Issuer for this purpose,
which may include one or more of the Initial Purchasers. On or after the occurrence of a Merger Event, the Last Reported Sale Price of a Unit of Reference Property will be determined in accordance with this definition or, if it cannot be so
determined, then it will be determined by the Board of Directors in a commercially reasonable manner and in accordance with the procedures described in this Indenture. 

“Make-Whole Fundamental Change” means any transaction or event that would constitute a Fundamental Change (determined after
giving effect to any exceptions or exclusions to such definition, but without regard to the proviso in clause (2) of the definition thereof). 

  
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 “Make-Whole Fundamental Change Effective Date” has the meaning specified in
Section 7.06(a). 
 “Make-Whole Fundamental Change Period” has the meaning specified in Section 7.06(a). 

“Market Disruption Event” means, if the Ordinary Shares (or such other security, as the case may be) are listed for trading
on The NASDAQ Global Select Market or listed on another U.S. national or regional securities exchange, the occurrence or existence during the one-half hour period ending on the scheduled close of trading on any Trading Day of any material suspension
or limitation imposed on trading (by reason of movements in price exceeding limits permitted by the relevant securities exchange or otherwise) in the Ordinary Shares (or such other security, as the case may be) or in any options contracts or futures
contracts relating to the Ordinary Shares (or such other security, as the case may be). 
 “Maturity Date” means
March 15, 2022. 
 “Measurement Period” has the meaning specified in Section 7.01(b). 

“Merger Event” has the meaning specified in Section 7.07(a). 

“Notes” has the meaning specified in the first paragraph of the Recitals of the Issuer, and includes any Note or Notes, as
the case may be, authenticated and delivered under this Indenture, including any Global Note. 
 “Notice of Default” means
written notice provided to the Issuer by the Trustee or to the Issuer and the Trustee by the Holders of not less than 25% in aggregate principal amount of Notes outstanding of a Default by the Issuer or the Guarantor, which notice must specify the
Default, demand that it be remedied and expressly state that such notice is a “Notice of Default.” 
 “Notice of
Provisional Redemption” has the meaning specified in Section 5.02(a). 
 “Notice of Tax Redemption” has the
meaning specified in Section 5.02(a). 
 “Notice of Tax Redemption Election” has the meaning specified in Section 5.03(b).

 “Observation Period” means, with respect to any Note surrendered for exchange: 

(1)         if the relevant Exchange Date occurs on or after the date the Issuer
issues a Notice of Tax Redemption or Notice of Provisional Redemption, as applicable, but prior to the relevant Redemption Date, the 40 consecutive VWAP Trading Days beginning on and including the
42nd Scheduled Trading Day (or, if such Scheduled Trading Day is not a VWAP Trading Day, the immediately following VWAP Trading Day) immediately preceding such Redemption Date; 

  
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 (2)         if the relevant Exchange
Date occurs on or after December 15, 2021, the 40 consecutive VWAP Trading Days beginning on and including the 42nd Scheduled Trading Day (or, if such Scheduled Trading Day is not a VWAP
Trading Day, the immediately following VWAP Trading Day) immediately preceding the Maturity Date; and 
 (3)
        in all other instances, if the relevant Exchange Date occurs prior to December 15, 2021, the 40 consecutive VWAP Trading Day period beginning on and including the third VWAP Trading Day
immediately succeeding such Exchange Date. 
 “Offering Memorandum” means the Preliminary Offering Memorandum, dated
March 4, 2015, as supplemented by the related pricing term sheet, dated March 5, 2015, relating to the offering and sale of the Initial Notes. 

“Officer” or “officer” shall mean, any Director of the Issuer, the Chairman of the Board of Directors, the
Chairman of the Guarantor’s Board of Directors and with respect to either the Issuer and/or the Guarantor, the Chief Executive Officer, the President, the Chief Financial Officer, a vice president (whether or not designated by a number or word
or words added before or after the title “vice president”), the Secretary, any Assistant Secretary, the Treasurer or any Assistant Treasurer. 

“Officer’s Certificate” means a certificate signed by an Officer and delivered to the Trustee. 

“Open of Business” means 9:00 a.m., New York City time. 

“Opinion of Counsel” means a written opinion of counsel, who may be external or in-house counsel for the Issuer or the
Guarantor. 
 “Ordinary Share Capital” of any Person means the Share Capital of such Person that is generally entitled
(a) to vote in the election of directors of such Person or (b) if such Person is not a corporation, to vote or otherwise participate in the selection of the governing body, partners, managers or others that will control the management or
policies of such Person. 
 “Ordinary Share Price” has the meaning specified in Section 7.06(b). 

“Ordinary Shares” means ordinary shares of the Guarantor, nominal value $0.0001 per share, at the date of the Indenture,
subject to Section 7.07. 
 “outstanding” when used with reference to Notes, shall, subject to the provisions of Section
1.05 mean, as of any particular time, all Notes authenticated and delivered by the Trustee under this Indenture, except: 

(1)         Notes theretofore canceled by the Trustee or accepted by the Trustee for
cancellation; 

  
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 (2)         Notes, or portions thereof,
that have become due and payable and in respect of which monies in the necessary amount shall have been deposited in trust with the Trustee or with any Paying Agent (other than the Issuer or the Guarantor) or shall have been set aside and segregated
in trust by the Issuer (if the Issuer shall act as its own Paying Agent); 
 (3)
        Notes that have been paid pursuant to Section 3.08 and Notes in lieu of which, or in substitution for which, other Notes shall have been authenticated and delivered pursuant to the terms of Section
3.08 unless proof satisfactory to the Trustee is presented that any such Notes are held by protected purchasers in whose hands such Notes are valid obligations of the Issuer; 

(4)         Notes exchanged pursuant to Article 7 and required to be cancelled
pursuant to Section 3.11; and 
 (5)         Notes repurchased by the Issuer or
Guarantor pursuant to the penultimate sentence of the first paragraph of Section 3.11. 
 “Paying Agent” means any Person
(including the Issuer) authorized by the Issuer to pay the principal amount of, interest on, the Redemption Price of, the Additional Amounts on, the Fundamental Change Repurchase Price of, any Notes on behalf of the Issuer. U.S. Bank National
Association shall initially be the Paying Agent. 
 “Person” means any individual, corporation, partnership, private
limited company, joint venture, trust, unincorporated organization or government or any agency or political subdivision thereof. 

“Physical Notes” means permanent certificated Notes in registered form issued in denominations of $200,000 principal amount
and integral multiples of $1,000 in excess thereof. 
 “Physical Settlement” has the meaning specified in Section 7.03(a).

 “Provisional Redemption” has the meaning specified in Section 5.01(b). 

“Provisional Redemption Date” means, when used with respect to any Note to be redeemed pursuant to a Provisional Redemption,
the date fixed for such redemption pursuant to this Indenture. 
 “Provisional Redemption Price” has the meaning specified
in Section 5.01(b). 
 “Publicly Traded Securities” means Ordinary Share Capital or common equity interests (or depositary
receipts) that are traded on The New York Stock Exchange, The NASDAQ Global Market, The NASDAQ Capital Market or The NASDAQ Global Select Market (or any of their respective successors) or that will be so traded when issued or exchanged in connection
with the event, transaction or transactions or events that would otherwise constitute a Fundamental Change under clause (1) or (2) of the definition thereof. 

  
 11 








 “Purchase Agreement” means that certain Purchase Agreement, dated March 5,
2015, among the Issuer, the Guarantor and the representatives of the Initial Purchasers, on behalf of the Initial Purchasers. 

“Qualified Institutional Buyer” (or “QIB”) has the meaning specified in Rule 144A. 

“Record Date” means, with respect to any dividend, distribution or other transaction or event in which the holders of the
Ordinary Shares (or other applicable security) have the right to receive any cash, securities or other property or in which the Ordinary Shares (or other applicable security) is exchanged for or converted into any combination of cash, securities or
other property, the date fixed for determination of holders of the Ordinary Shares (or other applicable security) entitled to receive such cash, securities or other property (whether such date is fixed by the Guarantor’s Board of Directors,
statute, contract or otherwise). 
 “Redemption Date” means the date fixed by the Issuer for Tax Redemption and/or
Provisional Redemption, as the case may be, pursuant to this Indenture, which must be a Business Day. 
 “Redemption
Notice” means a Notice of Tax Redemption or Notice of Provisional Redemption, as the case may be, pursuant to this Indenture. 

“Redemption Notice Date” means the Tax Redemption Notice Date or the date the Issuer delivers a Notice of Provisional
Redemption, as the case may be, pursuant to this Indenture. 
 “Redemption Price” means the price fixed for Tax Redemption
or Provisional Redemption, as the case may be, pursuant to this Indenture. 
 “Reference Property” has the meaning
specified in Section 7.07(a). 
 “Register” and “Registrar” have the respective meanings specified in
Section 3.05(a). 
 “Regular Record Date” means, with respect to the payment of interest on the Notes, the Close of
Business on March 1 or September 1, as the case may be, immediately preceding the relevant Interest Payment Date. 

“Relevant Taxing Jurisdiction” has the meaning specified in Section 4.10. 

“Reporting Default” has the meaning specified in Section 9.04(a). 

“Resale Restriction Termination Date” has the meaning specified in Section 3.07(b)(ii). 

“Restricted Global Note” has the meaning specified in Section 3.07(b)(i). 

  
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 “Restricted Note” has the meaning specified in Section 3.06(a)(i). 

“Restricted Notes Legend” means a legend substantially in the form set forth in Section 2.02. 

“Restricted Stock” has the meaning specified in Section 3.06(b)(i). 

“Restricted Stock Legend” means a legend substantially in the form set forth in Exhibit A hereto. 

“Rule 144” means Rule 144 under the Securities Act (including any successor rule thereto), as the same may be amended from
time to time. 
 “Rule 144A” means Rule 144A under the Securities Act (including any successor rule thereto), as the same
may be amended from time to time. 
 “Scheduled Trading Day” means a day that is scheduled to be a Trading Day (or VWAP
Trading Day, as applicable) on the primary U.S. national or regional securities exchange or market on which the Ordinary Shares (or such other security, as applicable) are listed or admitted for trading. If the Ordinary Shares (or such other
security, as applicable) are not so listed or admitted for trading, “Scheduled Trading Day” means a “Business Day.” 

“Securities Act” means the U.S. Securities Act of 1933, as amended, and the rules and regulations of the Commission
promulgated thereunder. 
 “Settlement Method” has the meaning specified in Section 7.03(a). 

“Share Capital” means any and all shares, interests, participations, rights or other equivalents (however designated) of
corporate stock and, with respect to partnerships, partnership interests (whether general or limited) and any other interest or participation that confers on a Person the right to receive a share of the profits and losses of, or distributions of
assets of, such partnership. 
 “Shelf Registration Statement” means a registration statement of the Issuer and the
Guarantor filed with the Commission on either (i) Form S-3 (or any successor form or other appropriate form under the Securities Act) or (ii) if the Issuer and the Guarantor are not permitted to file a registration statement on Form S-3,
an evergreen registration statement on Form S-1 (or any successor form or other appropriate form under the Securities Act), in each case for an offering to be made on a continuous or delayed basis pursuant to Rule 415 under the Securities Act
covering the Notes (including the Guarantee) and any Ordinary Shares issuable upon exchange of the Notes. 
 “Significant
Subsidiary” means, for purposes of Section 9.01(a)(vii)-(ix), a Subsidiary that is a “significant subsidiary” as defined under Rule 1-02(w) of Regulation S-X under the Exchange Act; provided that, in the case of a
Subsidiary that meets the criteria of clause (3) of the definition thereof but not clause (1) or (2) thereof, such Subsidiary shall be deemed not to be a Significant Subsidiary unless the Subsidiary’s income (or loss) from
continuing operations before income taxes, extraordinary items and cumulative effect of a change in accounting principles exclusive of amounts attributable to any non-controlling interests for the last completed fiscal year prior to the date of such
determination exceeds $10.0 million. 

  
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 “Specified Dollar Amount” means the dollar amount per $1,000 principal amount of
Notes to be received upon exchange as specified in the notice specifying the Issuer’s chosen Settlement Method (or deemed so specified). 

“Spin-Off” has the meaning specified in Section 7.05(c). 

“Subsidiary” means, with respect to any Person, any corporation, association, partnership or other business entity of which
more than 50% of the total voting power of shares of Share Capital or other interests (including partnership interests) entitled (without regard to the occurrence of any contingency) to vote in the election of directors, managers, general partners
or trustees thereof is at the time owned or controlled, directly or indirectly, by (i) the Guarantor; (ii) the Guarantor and one or more Subsidiaries of the Guarantor; or (iii) one or more Subsidiaries of the Guarantor. 

“Tax Redemption” has the meaning specified in Section 5.01(a). 

“Tax Redemption Date” means, when used with respect to any Note to be redeemed pursuant to a Tax Redemption, the date fixed
for such Tax Redemption pursuant to this Indenture. 
 “Tax Redemption Notice Date” means the date the Issuer delivers a
Tax Redemption Notice pursuant to this Indenture. 
 “Tax Redemption Price” has the meaning specified in Section 5.01(a).

 “Trading Day” means a Scheduled Trading Day on which (i) trading in the Ordinary Shares (or such other security, as
the case may be) generally occurs on The NASDAQ Global Select Market or, if the Ordinary Shares (or such other security, as the case may be) are not then listed on The NASDAQ Global Select Market, on the principal other U.S. national or regional
securities exchange on which the Ordinary Shares (or such other security, as the case may be) are then listed or, if the Ordinary Shares (or such other security, as the case may be) are not then listed on a U.S. national or regional securities
exchange, on the principal other market on which the Ordinary Shares (or such other security, as the case may be) are then traded, (ii) a Last Reported Sale Price for Ordinary Shares (or closing sale price for such other security) is available
on such securities exchange and (iii) there is no Market Disruption Event. If the Ordinary Shares are not so listed or traded, “Trading Day” means “Business Day.” 

“Trading Price” of the Notes on any date of determination means the average of the secondary market bid quotations obtained
by the Bid Solicitation Agent for $5.0 million principal amount of Notes at approximately 3:30 p.m., New York City time, on such determination date from three independent nationally recognized securities dealers selected by the Issuer, which may
include one or more of the Initial Purchasers; provided, that if three such bids cannot reasonably be obtained by the Bid Solicitation Agent but two such bids are obtained, then the average of the two bids shall be used, and if only one such
bid can reasonably be obtained by the Bid Solicitation Agent, that one bid shall be used. If the Bid Solicitation Agent 

  
 14 








 
cannot reasonably obtain at least one bid for $5.0 million principal amount of Notes from a nationally recognized securities dealer selected by the Issuer, then the Trading Price per $1,000
principal amount of Notes will be deemed to be less than 98% of the product of the Last Reported Sale Price of the Ordinary Shares and the applicable Exchange Rate. 

“Transfer Taxes” has the meaning specified in Section 4.10. 

“Trust Indenture Act” means the Trust Indenture Act of 1939, as amended. 

“Trust Officer” shall mean, when used with respect to the Trustee, any officer within the corporate trust department of the
Trustee, including any vice president, assistant vice president, assistant secretary, assistant treasurer, trust officer or any other officer of the Trustee who customarily performs functions similar to those performed by the Persons who at the time
shall be such officers, respectively, or to whom any corporate trust matter is referred because of such person’s knowledge of and familiarity with the particular subject and who shall have direct responsibility for the administration of this
Indenture. 
 “Trustee” means the Person named as the “Trustee” in the first paragraph of this Indenture
until a successor Trustee shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Trustee” shall mean such successor Trustee. 

“Unit of Reference Property” has the meaning set forth in Section 7.07(a). 

“Valuation Period” has the meaning set forth in Section 7.05(c). 

“VWAP Market Disruption Event” means (i) a failure by the primary U.S. national or regional securities exchange or
market on which the Ordinary Shares are listed or admitted for trading to open for trading during its regular trading session or (ii) the occurrence or existence prior to 1:00 p.m., New York City time, on any Scheduled Trading Day for the
Ordinary Shares for more than one half hour period in the aggregate during regular trading hours of any suspension or limitation imposed on trading (by reason of movements in price exceeding limits permitted by the relevant securities exchange or
otherwise) in the Ordinary Shares or in any options contracts or futures contracts relating to the Ordinary Shares. 
 “VWAP Trading
Day” means a day on which (i) there is no VWAP Market Disruption Event and (ii) trading in the Ordinary Shares generally occurs on The NASDAQ Global Select Market or, if the Ordinary Shares are not then listed on The NASDAQ Global
Select Market, on the primary other U.S. national or regional securities exchange on which the Ordinary Shares are then listed or, if the Ordinary Shares are not then listed on a U.S. national or regional securities exchange, on the principal other
market on which the Ordinary Shares are then listed or admitted for trading. If Ordinary Shares are not so listed or admitted for trading, “VWAP Trading Day” means a “Business Day.” 

“Wholly Owned Subsidiary” means, with respect to any Person, any Subsidiary of such Person, except that, solely for purposes
of this definition, the reference to “50%” in the definition of “Subsidiary” shall be deemed replaced by a reference to “100%,” the calculation of which shall exclude nominal amounts of the voting power of shares of
Share Capital or other interests in the relevant Subsidiary as may be required to satisfy local minority interest requirements outside the United States. 

  
 15 








 Section 1.02     References to Interest. Unless the context
otherwise requires, any reference to interest on, or in respect of, any Note in this Indenture shall be deemed to include Additional Interest if, in such context, Additional Interest is, was or would be payable pursuant to any of Section 4.06(a),
Section 4.06(b) and Section 9.04. Unless the context otherwise requires, any express mention of Additional Interest in any provision hereof shall not be construed as excluding Additional Interest in those provisions hereof where such express mention
is not made. 
 Section 1.03     Compliance Certificates and Opinions. Upon any application or request by
the Issuer to the Trustee to take, or refrain from taking, any action under any provision of this Indenture, the Issuer shall, if requested by the Trustee, furnish to the Trustee an Opinion of Counsel and Officer’s Certificate each stating
that, in the opinion of the signer, all conditions precedent, if any, provided for in the Indenture relating to the proposed action have been complied with. Notwithstanding the foregoing, no Opinion of Counsel shall be required under this Section
1.03 in connection with the issuance of the Initial Notes. 
 Every certificate or opinion with respect to compliance with a condition or
covenant provided for in this Indenture shall include: 
 (a)         a statement
that each individual signing such certificate or opinion has read such covenant or condition and the definitions herein relating thereto; 

(b)         a brief statement as to the nature and scope of the examination or
investigation upon which the statements or opinions contained in such certificate or opinion are based; 
 (c)
        a statement that, in the opinion of each such individual, such individual has made such examination or investigation as is necessary to enable such individual to express an informed opinion as to
whether or not such covenant or condition has been complied with; and 
 (d)
        a statement as to whether, in the opinion of each such individual, such condition or covenant has been complied with. 

In giving any Opinion of Counsel, counsel may rely as to factual matters on an Officer’s Certificate or certificates of public officials.

 Section 1.04     Form of Documents Delivered to Trustee. In any case where several matters are required
to be certified by, or covered by an opinion of, any specified Person, it is not necessary that all such matters be certified by, or covered by the opinion of, only one such Person, or that they be so certified or covered by only one document, but
one such Person may certify or give an opinion with respect to some matters and one or more other such Persons as to other matters, and any such Person may certify or give an opinion as to such matters in one or several documents. 

  
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 Any certificate or opinion of an officer of the Issuer may be based, insofar as it relates to
legal matters, upon a certificate or opinion of, or representations by, counsel, unless such officer knows, or in the exercise of reasonable care should know, that the certificate or opinion or representations with respect to the matters upon which
his/her certificate or opinion is based are erroneous. Any such certificate or Opinion of Counsel may be based, insofar as it relates to factual matters, upon a certificate or opinion of, or representations by, an officer or officers of the Issuer
stating that the information with respect to such factual matters is in the possession of the Issuer, unless such counsel knows, or in the exercise of reasonable care should know, that the certificate or opinion or representations with respect to
such matters are erroneous. 
 Where any Person is required to make, give or execute two or more applications, requests, consents,
certificates, statements, opinions or other instruments under this Indenture, they may, but need not, be consolidated and form one instrument. 

Section 1.05     Acts of Holders; Record Dates. 

(a)         Any request, demand, authorization, direction, notice, consent, waiver or
other action provided by this Indenture to be given or taken by Holders may be embodied in and evidenced by one or more instruments of substantially similar tenor signed by such Holders in person or by their agents duly appointed in writing and,
except as herein otherwise expressly provided, such action shall become effective when such instrument or instruments are delivered to a Trust Officer of the Trustee and, where it is hereby expressly required, to the Issuer. Such instrument or
instruments (and the action embodied therein and evidenced thereby) are herein sometimes referred to as an “Act” of the Holders signing such instrument or instruments. Proof of execution of any such instrument or of a writing
appointing any such agent shall be sufficient for any purpose of this Indenture and (subject to Section 11.01) conclusive in favor of the Trustee and the Issuer, if made in the manner provided in this Section. 

(b)         The fact and date of the execution by any Person of any such instrument or
writing may be proved by the affidavit of a witness of such execution or by a certificate of a notary public or other officer authorized by law to take acknowledgments of deeds, certifying that the individual signing such instrument or writing
acknowledged to him the execution thereof. Where such execution is by a signer acting in a capacity other than his individual capacity, such certificate or affidavit shall also constitute sufficient proof of his authority. The fact and date of the
execution of any such instrument or writing, or the authority of the Person executing the same, may also be proved in any other manner which the Trustee reasonably deems sufficient. 

(c)         The Issuer may, in the circumstances permitted by this Indenture, fix any
day as the record date for the purpose of determining the Holders entitled to give or take any request, demand, authorization, direction, notice, consent, waiver or other action, or to vote on any action, authorized or permitted to be given or taken
by Holders. If not set by the Issuer prior to the first solicitation of a Holder made by any Person in respect of any such action, or, in the case of any such vote, prior to such vote, the record date for any such action or vote shall be the 30th
day (or, if later, the date of the most recent list of Holders required to be provided pursuant to Section 12.01) prior to such first solicitation 

  
 17 








 
or vote, as the case may be. With regard to any record date, only the Holders on such date (or their duly designated proxies) shall be entitled to give or take, or vote on, the relevant action.

 (d)         The ownership of Notes shall be proved by the Register. 

(e)         In determining whether the Holders of the requisite aggregate principal
amount of Notes have concurred in any direction, consent, waiver or other action under this Indenture, Notes that are owned by the Guarantor, by any Subsidiary thereof (including the Issuer) or by any Person directly or indirectly controlling or
controlled by or under direct or indirect common control with the Guarantor or any Subsidiary thereof (including the Issuer) shall be disregarded and deemed not to be outstanding for the purpose of any such determination; provided that for
the purposes of determining whether the Trustee shall be protected in relying on any such direction, consent, waiver or other action only Notes that a Trust Officer actually knows are so owned shall be so disregarded. 

(f)         Any request, demand, authorization, direction, notice, consent, waiver or
other Act of the Holder of any Note shall bind every future Holder of the same Note and the Holder of every Note issued upon the registration of transfer thereof or in exchange therefor or in lieu thereof in respect of anything done, omitted or
suffered to be done by the Trustee or the Issuer in reliance thereon, whether or not notation of such action is made upon such Note. 

Section 1.06     Notices, Etc., to Trustee and the Issuer. Any request, demand, authorization, direction,
notice, consent, waiver or Act of Holders or other document provided or permitted by this Indenture to be made upon, given or furnished to, or filed with: 

(a)         the Trustee by any Holder or by the Issuer shall be sufficient for every
purpose hereunder if made, given, furnished or filed in writing (including telecopy and, in the case of notices with respect to Global Notes, electronic transmission through the facilities of the Depositary) to or with the Trustee at its applicable
Corporate Trust Office; or 
 (b)         the Issuer by the Trustee or by any Holder
shall be sufficient for every purpose hereunder (unless otherwise herein expressly provided) if in writing (including telecopy and, in the case of notices with respect to Global Notes, electronic transmission) and mailed, first-class postage
prepaid, to the Issuer addressed to it at the addresses specified in Section 16.02, or at any other address previously furnished in writing to the Trustee by the Issuer, Attention: Directors. 

Section 1.07     Notice to Holders; Waiver. Where this Indenture provides for notice to Holders of any event,
such notice shall be sufficiently given (unless otherwise herein expressly provided) if in writing (including telecopy and, in the case of notices with respect to Global Notes, electronic transmission through the facilities of the Depositary) and,
in the case of Physical Notes, mailed, first-class postage prepaid, to each Holder affected by such event, at such Holder’s address as it appears in the Register, not later than the latest date (if any), and not


  
 18 








 
earlier than the earliest date (if any), prescribed for the giving of such notice. In any case where notice to Holders is given by mail, neither the failure to mail such notice, nor any defect in
any notice so mailed, to any particular Holder shall affect the sufficiency of such notice with respect to other Holders. Where this Indenture provides for notice in any manner, such notice may be waived in writing by the Person entitled to receive
such notice, either before or after the event, and such waiver shall be the equivalent of such notice. Waivers of notice by Holders shall be filed with the Trustee, but such filing shall not be a condition precedent to the validity of any action
taken in reliance upon such waiver. 
 Whenever under this Indenture the Trustee is required to provide any notice by mail, in all cases the
Trustee may alternatively provide notice by overnight courier, by electronic delivery in pdf format or by facsimile, with confirmation of transmission. 

ARTICLE 2 
 SECURITY FORMS 

Section 2.01     Forms Generally. The Notes and the Trustee’s certificates of authentication shall be in
substantially the forms set forth in this Article, with such appropriate insertions, omissions, substitutions and other variations as are required or permitted by this Indenture, and may have such letters, numbers or other marks of identification
and such legends or endorsements placed thereon as may be required to comply with the rules of any securities exchange or Depositary therefor, the Code and regulations thereunder, or as may, consistently herewith, be determined by the Officer or
Officers executing such Notes, as evidenced by their execution thereof. 
 The Notes shall initially be issued in the form of permanent
Global Notes in registered form in substantially the form set forth in this Article. The aggregate principal amount of the Global Notes may from time to time be increased or decreased by adjustments made on the records of the Trustee, as FAST agent
for the Depositary, as hereinafter provided. 
 Section 2.02     Form of Face of Note. 

[Include the following legend for Global Notes only (the “Global Notes Legend”):] 

[THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF THE
DEPOSITARY OR A NOMINEE THEREOF. THIS SECURITY MAY NOT BE EXCHANGED IN WHOLE OR IN PART FOR A SECURITY REGISTERED, AND NO TRANSFER OF THIS SECURITY IN WHOLE OR IN PART MAY BE REGISTERED, IN THE NAME OF ANY PERSON OTHER THAN SUCH DEPOSITARY OR A
NOMINEE THEREOF, EXCEPT IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE. 
 UNLESS THIS CERTIFICATE IS PRESENTED BY AN
AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (“DTC”), A NEW YORK CORPORATION, TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF
CEDE & CO. OR IN SUCH OTHER NAME AS IS 

  
 19 








 
REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER,
PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL IN AS MUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN.] 

[Include the following legend on all Notes that are Restricted Notes (the “Restricted Notes
Legend”):] 
 [THIS SECURITY AND THE ORDINARY SHARES, IF ANY, DELIVERABLE UPON EXCHANGE OF THIS
SECURITY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE FOLLOWING SENTENCE. BY ITS ACQUISITION
HEREOF OR OF A BENEFICIAL INTEREST HEREIN, THE ACQUIRER: 
 (1)
        REPRESENTS THAT IT AND ANY ACCOUNT FOR WHICH IT IS ACTING IS A “QUALIFIED INSTITUTIONAL BUYER” (WITHIN THE MEANING OF RULE 144A UNDER THE SECURITIES ACT) AND THAT IT EXERCISES SOLE INVESTMENT
DISCRETION WITH RESPECT TO EACH SUCH ACCOUNT; AND 
 (2)         AGREES FOR THE
BENEFIT OF THE ISSUER THAT IT WILL NOT OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER THIS SECURITY OR ANY BENEFICIAL INTEREST HEREIN PRIOR TO THE DATE THAT IS THE LATER OF (X) ONE YEAR AFTER THE LAST ORIGINAL ISSUE DATE HEREOF OR SUCH SHORTER
PERIOD OF TIME AS PERMITTED BY RULE 144 UNDER THE SECURITIES ACT OR ANY SUCCESSOR PROVISION THERETO AND (Y) SUCH LATER DATE, IF ANY, AS MAY BE REQUIRED BY APPLICABLE LAW, EXCEPT: 

(A)         TO HORIZON PHARMA INVESTMENT LIMITED (THE “ISSUER”), HORIZON
PHARMA PUBLIC LIMITED COMPANY (THE “GUARANTOR”) OR ANY OF THEIR RESPECTIVE SUBSIDIARIES, OR 
 (B)
        PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE SECURITIES ACT, OR 

  
 20 








 (C)         TO A QUALIFIED INSTITUTIONAL
BUYER IN COMPLIANCE WITH RULE 144A UNDER THE SECURITIES ACT, OR 
 (D)
        PURSUANT TO AN EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT OR ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

PRIOR TO THE REGISTRATION OF ANY TRANSFER IN ACCORDANCE WITH CLAUSE (2)(D) ABOVE, THE ISSUER, THE GUARANTOR AND THE TRUSTEE RESERVE
THE RIGHT TO REQUIRE THE DELIVERY OF SUCH LEGAL OPINIONS, CERTIFICATIONS OR OTHER EVIDENCE AS MAY REASONABLY BE REQUIRED IN ORDER TO DETERMINE THAT THE PROPOSED TRANSFER IS BEING MADE IN COMPLIANCE WITH THE SECURITIES ACT AND APPLICABLE STATE
SECURITIES LAWS. NO REPRESENTATION IS MADE AS TO THE AVAILABILITY OF ANY EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

  
 21 








 2.50% Exchangeable Senior Notes due 2022 

 

			
	No. [    ]		U.S. $[            ]
		
	CUSIP NO.   [    ]		
		
	ISIN NO.        [    ]		

 Horizon Pharma Investment Limited, a Bermuda exempted company limited by shares (herein called the
“Issuer”), which term includes any successor corporation under the Indenture referred to on the reverse hereof), for value received hereby promises to pay to
[                    ], or registered assigns, the principal sum of
[                ] UNITED STATES DOLLARS (U.S. $[            ]) (which amount may from time to time be
increased or decreased by adjustments made on the records of the Trustee, as custodian for the Depositary, in accordance with the rules and procedures of the Depositary and in accordance with the below referred Indenture) on March 15, 2022. The
principal amount of Physical Notes and interest thereon, as provided on the reverse hereof, shall be payable at the Corporate Trust Office and at any other office or agency maintained by the Issuer for such purpose. The Paying Agent will pay
principal of any Global Note and interest thereon, as provided on the reverse hereof, in immediately available funds to The Depository Trust Company or its nominee, as the case may be, as the registered holder of such Global Note, on each Interest
Payment Date, Redemption Date, Fundamental Change Repurchase Date or other payment date, as the case may be. The Notes will be fully and unconditionally guaranteed by Horizon Pharma Public Limited Company, a public limited company formed under the
laws of Ireland (the “Guarantor”), on a senior unsecured basis, in accordance with the provisions of Article 15 of the Indenture. 

Reference is made to the further provisions of this Note set forth on the reverse hereof, including, without limitation, provisions giving the
Holder the right to exchange this Note into cash, Ordinary Shares or a combination of cash and Ordinary Shares, at the Issuer’s election, to the ability and obligation of the Issuer to purchase this Note upon certain events, to pay Additional
Amounts on the Notes upon certain events and to redeem the Notes upon certain events, in each case, on the terms and subject to the limitations referred to on the reverse hereof and as more fully specified in the Indenture. Such further provisions
shall for all purposes have the same effect as though fully set forth at this place. Capitalized terms used but not defined herein shall have such meanings as are ascribed to such terms in the Indenture. In the case of any conflict between this Note
and the Indenture, the provisions of the Indenture shall control. 
 This Note shall not be valid or become obligatory for any purpose until
the certificate of authentication hereon shall have been manually signed by the Trustee or a duly authorized authenticating agent under the Indenture. 

  
 22 








 IN WITNESS WHEREOF, the Issuer has caused this Note to be duly executed. 

 

			
	 HORIZON PHARMA INVESTMENT LIMITED

		
	By:		  

			Name:
			Title:


 Dated:
                         , 2015 

TRUSTEE’S CERTIFICATE OF AUTHENTICATION 
 U.S. BANK
NATIONAL ASSOCIATION, 
 as Trustee, certifies that this is one of the Notes described 

in the within-named Indenture. 
  

			
	By:		  

			Authorized Signatory
			Name:


  
 23 








 Section 2.03     Form of Reverse of Note. 

HORIZON PHARMA INVESTMENT LIMITED 

2.50% Exchangeable Senior Notes due 2022 

This Note is one of a duly authorized issue of Notes of the Issuer, designated as its 2.50% Exchangeable Senior Notes due 2022 (the
“Notes”), all issued or to be issued under and pursuant to an Indenture dated as of March 13, 2015 (the “Indenture”), among the Issuer, the Guarantor and U.S. Bank National Association, as Trustee (the
“Trustee”), to which Indenture and all indentures supplemental thereto reference is hereby made for a description of the rights, limitations of rights, obligations, duties and immunities thereunder of the Trustee, the Issuer, the
Guarantor and the Holders of the Notes. The Indenture provides that Additional Notes may be issued thereunder, if certain conditions are met. 

Interest. The Notes will bear interest at a rate of 2.50% per year. Interest on the Notes will accrue from, and including,
March 13, 2015, or from the most recent date to which interest has been paid or duly provided for. Interest will be payable semiannually in arrears on each Interest Payment Date, beginning on September 15, 2015. Pursuant to the Indenture,
in certain circumstances, the Holders of Notes shall be entitled to receive Additional Interest. 
 Interest will be paid to the person in
whose name a Note is registered at the Close of Business on the March 1 or September 1 (whether or not such date is a Business Day), as the case may be, immediately preceding the relevant Interest Payment Date. Interest on the Notes will
be computed on the basis of a 360-day year composed of twelve 30-day months and, for partial months, on the basis of the number of days actually elapsed in a 30-day month. 

Interest will cease to accrue on a Note in the circumstances provided in the Indenture. 

Additional Amounts. The Issuer, the Guarantor or any successor to the Issuer or the Guarantor, as applicable, will make all payments
and deliveries on account of the Notes without withholding or deduction for taxes imposed by a relevant jurisdiction, unless such withholding or deduction is required by law. If any such withholding or deduction is required, the Issuer, the
Guarantor or any successor to the Issuer or the Guarantor, as applicable, will, in certain cases and subject to certain exceptions, pay such Additional Amounts as may be necessary so that the net amount received by beneficial owners of the Notes
after such withholding or deduction will not be less than the amount that would have been received in the absence of such withholding or deduction. 

Redemption at the Option of the Issuer. The Issuer may redeem the Notes at its option, prior to March 15, 2022, in whole but not
in part, in connection with a Change in Tax Law that results in Additional Amounts becoming due and payable in respect of payments and/or deliveries on the Notes. The Issuer also may redeem the Notes at its option on or after March 20, 2019, in
whole or in part, if the Last Reported Sale Price of the Ordinary Shares has been at least 130% of the Exchange Price then in effect for at least 20 Trading Days (whether or not consecutive) during any 30 consecutive Trading Day period ending on,
and including, the Trading Day immediately preceding the date on which the Issuer provides Notice of Provisional Redemption. Upon any such redemption, the Issuer shall pay the Tax Redemption Price or the Provisional Redemption Price, as applicable,
as set forth in the Indenture. No sinking fund is provided for the Notes. 

  
 24 








 Repurchase at the Option of the Holder Upon a Fundamental Change. Subject to the terms and
conditions of the Indenture, the Issuer shall become obligated, at the option of the Holder, to repurchase the Notes if a Fundamental Change occurs at a repurchase price specified in the Indenture. 

Exchange. Subject to and upon compliance with the provisions of the Indenture (including without limitation the conditions of exchange
of this Note set forth in Article 7 thereof), the Holder hereof has the right, at its option, during certain periods and upon the occurrence of certain conditions specified in the Indenture, to exchange the principal amount hereof or a certain
portion specified in the Indenture of such principal amount for the Exchange Consideration. The Exchange Rate (and equivalent Exchange Price) are set forth in the Indenture and subject to adjustment in certain events described in the Indenture. Upon
exchange, the Issuer will deliver or cause to be delivered, as applicable, cash, Ordinary Shares or a combination of cash and Ordinary Shares as set forth in the Indenture. No fractional Ordinary Share will be issued upon any exchange, but a payment
in cash will be made, as provided in the Indenture, in respect of any fraction of an Ordinary Share which would otherwise be issuable upon the surrender of any Notes for exchange. Notes in respect of which a Holder is exercising its right to require
repurchase on a Fundamental Change Repurchase Date may be exchanged only if such Holder withdraws the related election to exercise such right in accordance with the terms of the Indenture. 

In the event of a deposit or withdrawal of an interest in this Note, including an exchange, transfer, repurchase, redemption or exchange of
this Note in part only, the Trustee, as custodian of the Depositary, shall make an adjustment on its records to reflect such deposit or withdrawal in accordance with the rules and procedures of the Depositary. 

Acceleration of Maturity. Subject to certain exceptions in the Indenture, if an Event of Default shall occur and be continuing, the
principal amount plus accrued and unpaid interest, if any, through such date on all the Notes may be declared due and payable in the manner and with the effect provided in the Indenture. In case of certain events of bankruptcy, insolvency,
examinership or reorganization involving the Issuer or the Guarantor, such principal and accrued and unpaid interest, if any, shall be due and payable immediately without action by any Holder or the Trustee. 

Supplemental Indentures with Consent of Holders; Waiver of Past Defaults. The Indenture permits, with certain exceptions as therein
provided, the amendment thereof and the modification of the rights and obligations of the Issuer and the Guarantor and the rights of the Holders of the Notes under the Indenture at any time by the Issuer and the Trustee with the consent of the
Holders of not less than a majority in aggregate principal amount of the outstanding Notes. The Indenture also contains provisions permitting the Holders of specified percentages in aggregate principal amount of the outstanding Notes, on behalf of
the Holders of all the Notes, to waive compliance by the Issuer and the Guarantor with certain provisions of the Indenture and certain past Defaults and Events of Default under the Indenture and their consequences (other than with respect to
non-payment, a failure to satisfy the Exchange 

  
 25 








 
Obligation or a provision that cannot be waived without the consent of each Holder affected). Any such consent or waiver by the Holder of any provision of or applicable to this Note shall be
conclusive and binding upon such Holder and upon all future Holders of this Note and of any Note issued upon the registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such consent or waiver is made upon
this Note. 
 Registration of Transfer and Exchange. As provided in the Indenture and subject to certain limitations therein set
forth, the transfer of this Note is registrable in the Register, upon surrender of this Note for registration of transfer at the office or agency of the Issuer specified in accordance with the Indenture, duly endorsed by, or accompanied by a written
instrument of transfer in form satisfactory to the Issuer and the Registrar duly executed by, the Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes, of authorized denominations and for the same aggregate
principal amount, will be issued to the designated transferee or transferees. 
 No service charge shall be made for any such registration
of transfer or exchange, but the Issuer and the Registrar may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

Prior to due presentment of this Note for registration of transfer, the Issuer, the Guarantor, the Trustee and the Registrar and any agent of
the Issuer or the Trustee may treat the Person in whose name this Note is registered as the owner hereof for all purposes, whether or not this Note be overdue, and neither the Issuer, the Guarantor, the Trustee nor any such agent shall be affected
by notice to the contrary. 
 Denominations. The Notes are issuable only in registered form in denominations of $200,000 and any
integral multiple of $1,000 in excess thereof, as provided in the Indenture and subject to certain limitations therein set forth. Notes are exchangeable for a like aggregate principal amount of Notes of a different authorized denomination, as
requested by the Holder surrendering the same pursuant to the terms of the Indenture. 
 This Note and any claim, controversy or dispute
arising under or related to this Note shall be governed by, and construed in accordance with, the laws of the State of New York. 
 All
terms used in this Note that are defined in the Indenture shall have the meanings assigned to them in the Indenture. 

  
 26 








 ASSIGNMENT FORM 

For value received
                         hereby sell(s), assign(s) and transfer(s) unto (Please insert social security or Taxpayer Identification
Number of assignee) the within Note, and hereby irrevocably constitutes and appoints                          attorney to
transfer the said Note on the books of the Issuer, with full power of substitution in the premises. 
 In connection with any transfer of a Restricted Note
occurring prior to the Resale Restriction Termination Date, as defined in the Indenture governing such Restricted Note, the undersigned confirms that such Restricted Note is being transferred: 

 

			
	 ̈		To Horizon Pharma Investment Limited, Horizon Pharma Public Limited Company or a respective subsidiary thereof; or
		
	 ̈		Pursuant to a registration statement which has become effective under the Securities Act of 1933, as amended; or
		
	 ̈		To a qualified institutional buyer in compliance with Rule 144A under the Securities Act; or
		
	 ̈		Pursuant to an exemption from registration provided by Rule 144 under the Securities Act, or any other available exemption from the registration requirements of the Securities Act.

 TO BE COMPLETED BY PURCHASER IF THE THIRD BOX ABOVE IS CHECKED 

The undersigned represents and warrants that it is purchasing this Restricted Note for its own account or an account with respect to which it
exercises sole investment discretion and that it and any such account is a “qualified institutional buyer” within the meaning of Rule 144A under the Securities Act and is aware that the sale to it is being made in reliance on Rule 144A and
acknowledges that it has received such information regarding the Issuer as the undersigned has requested pursuant to Rule 144A or has determined not to request such information and that it is aware that the transferor is relying upon the
undersigned’s foregoing representations in order to claim the exemption from registration provided by Rule 144A. 
  

									
	 Date:
		  
				Signed:		  


 Unless one of the above boxes is checked, the Trustee will refuse to register any of the Restricted Notes
evidenced by this certificate in the name of any Person other than the registered Holder thereof, provided that if the fourth box is checked, the Issuer, the Guarantor or the Trustee may require, prior to registering any such transfer of the
Notes, in its sole discretion, such legal opinions, certifications and other information as the Issuer, the Guarantor or the Trustee may reasonably request to confirm that such transfer is being made pursuant to an exemption from, or in a
transaction not subject to, the registration requirements of the Securities Act. 

  
 27 








 If none of the foregoing boxes is checked, the Trustee or Registrar shall not be obligated to register this Note
in the name of any Person other than the Holder hereof unless and until the conditions to any such transfer of registration set forth herein and in Section 3.10 of the Indenture shall have been satisfied. If this Note is not a Restricted Note, the
Trustee or Registrar shall not be obligated to register such Note in the name of any Person other than the Holder hereof unless and until the conditions to any such transfer of registration set forth herein and in Section 3.10 of the Indenture shall
have been satisfied. 
  

			
	Dated:		  

	
	  

	  

	Signature(s)
	
	  

	Signature Guarantee
	
	Signature(s) must be guaranteed by an eligible Guarantor Institution (banks, stock brokers, savings and loan associations and credit unions) with membership in an approved signature guarantee medallion program pursuant
to Securities and Exchange Commission Rule 17Ad-15 if Notes are to be delivered, other than to and in the name of the registered holder.

 NOTICE: The signature on the assignment must correspond with the name as written upon the face of the Note in every particular
without alteration or enlargement or any change whatever. 

  
 28 








 EXCHANGE NOTICE 

If you want to exchange this Note into cash, Ordinary Shares of the Guarantor or a combination of cash and Ordinary Shares, at the
Issuer’s election, check the box: 
 To exchange only part of this Note, state the principal amount to be exchanged (provided that the
principal amount of this Note not so exchanged is $200,000 or an integral multiple of $1,000 in excess thereof): 

$             

If you want the share certificate, if any, made out in another person’s name, fill in the form below: 

 
  

(Insert other person’s social security or tax ID no.) 
  

 
  

 
  

 
 (Print or type other person’s
name, address and zip code) 
 Signature Guarantee:
                                        

 Note: Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Registrar, which requirements
include membership or participation in the Note Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Registrar in addition to, or in substitution for, STAMP,
all in accordance with the Exchange Act of 1934, as amended. 

  
 29 








 [Form of Fundamental Change Repurchase Notice] 

To:     U.S. Bank National Association 

Corporate Trust Services 
 Global Corporate Trust Services 

Mailcode: EP-MN-WS3C 
 60 Livingston Avenue 

St. Paul, MN 55107-2292 
 Attention: Rick Prokosch – Horizon
Pharma Corporate Trust Administrator 
 Facsimile: (651) 466-7430 

The undersigned registered owner of this Note hereby acknowledges receipt of a notice from Horizon Pharma Investment Limited (the
“Issuer”) as to the occurrence of a Fundamental Change with respect to the Issuer and specifying the Fundamental Change Repurchase Date and requests and instructs the Issuer to pay to the registered holder hereof in accordance with
the applicable provisions of the Indenture referred to in this Note (1) the entire principal amount of this Note, or the portion thereof (provided that the principal amount of this Note not so repurchased is $200,000 principal amount or an
integral multiple of $1,000 in excess thereof) below designated, and (2) if such Fundamental Change Repurchase Date does not fall during the period after a Regular Record Date and on or prior to the corresponding Interest Payment Date, accrued
and unpaid interest, if any, thereon to, but excluding, such Fundamental Change Repurchase Date. 
 In the case of Physical Notes, the
certificate numbers of the Notes to be repurchased are as set forth below: 
 Dated:
                                        

  

			
			  

		
			Signature(s)
		
			  

		
			Social Security or Other Taxpayer
		
			Identification Number
		
			Principal amount to be repaid (if less than all):
$        ,000


 NOTICE: The above signature(s) of the Holder(s) hereof must correspond with the name as written upon the
face of the Note in every particular without alteration or enlargement or any change whatever. 

  
 30 








 ARTICLE 3 

THE SECURITIES 
 Section 3.01
    Title and Terms; Payments. 
 The aggregate principal amount of Notes that may be authenticated and delivered
under this Indenture is initially limited to $400.0 million (the “Initial Notes”), except for Notes authenticated and delivered upon registration or transfer of, or in exchange for, or in lieu of, other Notes pursuant to Sections
3.04, 3.05, 3.06, 3.07, 3.08, 3.10, 5.06, 7.02(c) or 8.06. The Issuer may, from time to time after the execution of this Indenture, execute and deliver to the Trustee for authentication Additional Notes of an unlimited aggregate principal amount,
and the Trustee shall thereupon authenticate and deliver said Additional Notes to or upon receipt of a Company Order, without any further action by the Issuer hereunder; provided, however, that (1) if any such Additional Notes are
not fungible with the Initial Notes for securities laws purposes or the U.S. federal income tax purposes, any such Additional Notes will have one or more separate CUSIP numbers so long as they remain not fungible; (2) such Additional Notes must
be issued pursuant to the same terms (other than the offering price, the issue date, when interest begins accruing, and the first interest payment date, with respect to such Additional Notes, and, if applicable, restrictions on transfer in respect
of such Additional Notes) as the Initial Notes; and (3) the Trustee must receive an Officer’s Certificate and Opinion of Counsel to the effect that such issuance of Additional Notes complies with the provisions of this Indenture, including
each provision of this paragraph. 
 The Notes shall be known and designated as the “2.50% Exchangeable Senior Notes due 2022” of
the Issuer. The principal amount shall be payable on the Maturity Date. 
 The principal amount of Physical Notes shall be payable at the
office of the Paying Agent, which initially shall be the Corporate Trust Office, and at any other office or agency maintained by the Issuer for such purpose. Interest on Physical Notes will be payable (i) to Holders holding Physical Notes
having an aggregate principal amount of $2.0 million or less of Notes, by check mailed to such Holders at the address set forth in the Register and (ii) to Holders holding Physical Notes having an aggregate principal amount of more than $2.0
million of Notes, either by check mailed to such Holders or, upon written application by a Holder to the Registrar not later than the relevant Regular Record Date for such interest payment, by wire transfer in immediately available funds to such
Holder’s account within the United States, which application shall remain in effect until the Holder notifies the Registrar to the contrary in writing. The Issuer will pay or cause the Paying Agent to pay principal of, and interest on, Global
Notes in immediately available funds to The Depository Trust Company or its nominee, as the case may be, as the registered holder of such Global Note, on each Interest Payment Date, Redemption Date, Fundamental Change Repurchase Date or other
payment date, as the case may be. 
 Any Notes repurchased by the Issuer or the Guarantor will be retired and no longer outstanding
hereunder. 

  
 31 








 Section 3.02     Denominations. The Notes shall be issuable only
in registered form without coupons and in denominations of $200,000 and any integral multiple of $1,000 in excess thereof. 

Section 3.03     Execution, Authentication, Delivery and Dating. The Notes shall be executed on behalf of the
Issuer by an Officer. 
 Notes bearing the manual or facsimile signatures of individuals who were at any time an Officer of the Issuer shall
bind the Issuer, notwithstanding that such individual has ceased to hold such office prior to the authentication and delivery of such Notes or did not hold such office at the date of such Notes. 

At any time and from time to time after the execution and delivery of this Indenture, the Issuer may deliver Notes executed by the Issuer to
the Trustee for authentication, together with a Company Order for the authentication and delivery of such Notes. The Company Order shall specify the amount of Notes to be authenticated, and shall further specify the amount of such Notes to be issued
as a Global Notes or as Physical Notes. The Trustee in accordance with such Company Order shall authenticate and deliver such Notes as in this Indenture provided and not otherwise. 

Each Note shall be dated the date of its authentication. 

No Note shall be entitled to any benefit under this Indenture or be valid or obligatory for any purpose unless there appears on such Note a
certificate of authentication substantially in the form provided for herein executed by the Trustee by manual signature, and such certificate upon any Note shall be conclusive evidence, and the only evidence, that such Note has been duly
authenticated and delivered hereunder. 
 Section 3.04     Temporary Notes. Pending the preparation of
Physical Notes, the Issuer may execute, and upon Company Order the Trustee shall authenticate and deliver, temporary Notes that are printed, lithographed, typewritten, mimeographed or otherwise produced, in any authorized denomination, substantially
of the tenor of the Physical Notes in lieu of which they are issued and with such appropriate insertions, omissions, substitutions and other variations as the Officer executing such Notes may determine, as evidenced by such Officer’s execution
of such Notes; provided, that any such temporary Notes shall bear legends on the face of such Notes as set forth in Section 2.02. 
 If
temporary Notes are issued, the Issuer will cause Physical Notes to be prepared without unreasonable delay. After the preparation of Physical Notes, the temporary Notes shall be exchangeable for Physical Notes upon surrender of the temporary Notes
at any office or agency of the Issuer designated pursuant to Section 4.02, without charge to the Holder. Upon surrender for cancellation of any one or more temporary Notes, the Issuer shall execute and the Trustee shall, upon Company Order,
authenticate and deliver in exchange therefor a like principal amount of Physical Notes of authorized denominations. Until so exchanged, the temporary Notes shall in all respects be entitled to the same benefits under this Indenture as Physical
Notes. 

  
 32 








 Section 3.05     Registration; Registration of Transfer and
Exchange. 
 (a)         The Issuer shall cause to be kept at the applicable
Corporate Trust Office of the Trustee a register (the register maintained in such office and in any other office or agency designated pursuant to Section 4.02 being herein sometimes collectively referred to as the “Register”) in
which, subject to such reasonable regulations as it may prescribe, the Issuer shall provide for the registration of Notes and of transfers of Notes. The Trustee is hereby appointed “Registrar” (the “Registrar”) for the
purpose of registering Notes and transfers of Notes as herein provided. 
 Upon surrender for registration of transfer of
any Note at an office or agency of the Issuer designated pursuant to Section 4.02 for such purpose, the Issuer shall execute, and the Trustee shall authenticate and deliver, in the name of the designated transferee or transferees, one or more new
Notes of any authorized denominations and of a like aggregate principal amount and tenor, each such Note bearing such restrictive legends as may be required by this Indenture (including Sections 2.02, 3.06 and 3.10). 

At the option of the Holder and subject to the other provisions of Section 3.06 and to Section 3.10, Notes may be exchanged
for other Notes of any authorized denominations and of a like aggregate principal amount and tenor, upon surrender of the Notes to be exchanged at such office or agency. Whenever any Notes are so surrendered for exchange, the Issuer shall execute,
and the Trustee shall, upon Company Order, authenticate and deliver, the Notes which the Holder making the exchange is entitled to receive. 

All Notes issued upon any registration of transfer or exchange of Notes shall be the valid obligations of the Issuer,
evidencing the same debt, and entitled to the same benefits under this Indenture, as the Notes surrendered upon such registration of transfer or exchange. 

Every Note presented or surrendered for registration of transfer or for exchange shall (if so required by the Issuer or the
Trustee) be duly endorsed, or be accompanied by a written instrument of transfer in form satisfactory to the Issuer and the Registrar duly executed, by the Holder thereof or his attorney duly authorized in writing. As a condition to the registration
of transfer of any Restricted Notes, the Issuer, the Guarantor or the Trustee may require evidence satisfactory to them as to the compliance with the restrictions set forth in the legend on such Notes. 

Neither the Issuer nor the Registrar shall be required to exchange or register a transfer of any Note in the circumstances set
forth in Section 3.10(a)(iv). 
 (b)         Neither any members of, or participants
in, the Depositary (collectively, the “Agent Members”) nor any other Persons on whose behalf any Agent Member may act shall have any rights under this Indenture with respect to any Global Note registered in the name of the
Depositary or any nominee thereof, or under any such Global Note, and the Depositary or such nominee, as the case may be, may be treated by the Issuer, the Trustee and any agent of the Issuer, the Guarantor or the Trustee as the absolute owner


  
 33 








 
and Holder of such Global Note for all purposes whatsoever. The Trustee shall have no responsibility or obligation to any Agent Members or any other Person on whose behalf Agent Members may act
with respect to (i) any ownership interests in the Global Note, (ii) the accuracy of the records of the Depositary or its nominee, (iii) any notice required hereunder or (iv) any payments under or with respect to the Global Note.
Notwithstanding the foregoing, nothing herein shall prevent the Issuer, the Guarantor, the Trustee or any agent of the Issuer, the Guarantor or the Trustee from giving effect to any written certification, proxy or other authorization furnished by
the Depositary or such nominee, as the case may be, or impair, as between the Depositary, its Agent Members and any other Person on whose behalf an Agent Member may act, the operation of customary practices of such Persons governing the exercise of
the rights of a Holder of any Note. The registered Holder of a Global Note may grant proxies and otherwise authorize any Person, including Agent Members and persons that may hold interests through Agent Members, to take any action that a Holder is
entitled to take under this Indenture or the Notes. 
 Section 3.06     Transfer Restrictions. 

(a)         Restricted Notes. 

(i)         Every Note (and all securities issued in exchange therefor or
substitution thereof, except any Ordinary Shares issued upon exchange thereof) that bears, or that is required under this Section 3.06 to bear, the Restricted Notes Legend will be deemed to be a “Restricted Note.” Each Restricted
Note will be subject to the restrictions on transfer set forth in this Indenture (including in the Restricted Notes Legend) and will bear a restricted CUSIP number for the Notes unless such restrictions on transfer are eliminated or otherwise waived
by written consent of the Issuer, and each Holder of a Restricted Note, by such Holder’s acceptance of such Restricted Note, will be deemed to be bound by the restrictions on transfer applicable to such Restricted Note. 

(ii)         Until the Resale Restriction Termination Date, any Restricted Note (or
any security issued in exchange therefor or substitution thereof, except any Ordinary Shares issued upon the exchange thereof, to which the provisions of Section 3.06(b)(ii) below shall apply) issued under this Indenture, if any, will bear the
Restricted Notes Legend unless: 
 (A)         such Note, since last held by the
Issuer or the Guarantor or an affiliate of the Issuer or the Guarantor (within the meaning of Rule 144), if ever, was transferred (1) to a Person other than (x) the Issuer or the Guarantor or (y) an affiliate of the Issuer or the
Guarantor (within the meaning of Rule 144) or a Person that was an affiliate of the Issuer or the Guarantor (within the meaning of Rule 144) within the three months immediately preceding such transfer and (2) pursuant to a registration
statement that was effective under the Securities Act at the time of such transfer; 

  
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 (B)         such Note was transferred
(1) to a Person other than (x) the Issuer or the Guarantor or (y) an affiliate of the Issuer or the Guarantor (within the meaning of Rule 144) or a Person that was an affiliate of the Issuer or the Guarantor (within the meaning of
Rule 144) within the three months immediately preceding such transfer and (2) pursuant to the exemption from registration provided by Rule 144 or any similar provision then in force under the Securities Act; or 

(C)         the Issuer delivers written notice to the Trustee and the Registrar
stating that the Restricted Notes Legend may be removed from such Note and all Applicable Procedures have been complied with. 

(iii)         In addition, until the Resale Restriction Termination Date, no transfer
of any Restricted Note will be registered by the Registrar prior to the Resale Restriction Termination Date unless the transferring Holder delivers the form of assignment set forth on the Restricted Note, with the appropriate box checked, to the
Trustee. 
 (iv)         Any Note that is repurchased or owned by any affiliate of
the Issuer or the Guarantor (within the meaning of Rule 144) may not be resold by such affiliate unless registered under the Securities Act or resold pursuant to an exemption from the registration requirements of the Securities Act in a transaction
that results in such note no longer being a “restricted security” (as defined in Rule 144 under the Securities Act). 

(v)         On and after the Resale Restriction Termination Date, any Note (or any
security issued in exchange therefor or substitution thereof, except any Ordinary Shares issued upon the exchange thereof) will bear the Restricted Notes Legend at any time the Issuer reasonably determinates that, to comply with law, such Note (or
such securities issued in exchange for or substitution of a Note) must bear the Restricted Notes Legend. 
 (b)
        Restricted Stock. 
 (i)
        Every Ordinary Share that bears, or that is required under this Section 3.06 to bear, the Restricted Stock Legend will be deemed to be “Restricted Stock.” Each share of Restricted
Stock will be subject to the restrictions on transfer set forth in this Indenture (including in the Restricted Stock Legend) and may bear a restricted CUSIP number unless such restrictions on transfer are eliminated or otherwise waived by written
consent of the Issuer, and each Holder of Restricted Stock, by such Holder’s acceptance of Restricted Stock, will be deemed to be bound by the restrictions on transfer applicable to such Restricted Stock. 

(ii)         Until the Resale Restriction Termination Date, any Ordinary Shares
issued upon the exchange of a Restricted Note, will bear the Restricted Stock Legend unless the Issuer delivers written notice to the Trustee, the Registrar 

  
 35 








 
and Ordinary Share Depositary (and/or other transfer agent for the Ordinary Shares) stating that such Ordinary Shares need not bear the Restricted Stock Legend. 

(iii)         On and after the Resale Restriction Termination Date, Ordinary Shares
issued upon the exchange of a Restricted Note, if any, will bear the Restricted Stock Legend at any time the Issuer reasonably determinates that, to comply with law, such Ordinary Shares must bear the Restricted Stock Legend. 

(c)         As used in this Section 3.06, the term “transfer” means
any sale, pledge, transfer, loan, hypothecation or other disposition whatsoever of any Restricted Note, any interest therein or any Restricted Stock. 

Section 3.07     Expiration of Restrictions. 

(a)         Physical Notes. Any Physical Note (or any security issued in
exchange or substitution therefor) that does not constitute a Restricted Note may be exchanged for a new Note or Notes of like tenor and aggregate principal amount that do not bear the Restricted Notes Legend required by Section 3.06. To exercise
such right of exchange, the Holder of such Note must surrender such Note in accordance with the provisions of Section 3.10 and deliver any additional documentation reasonably required by the Issuer, the Trustee or the Registrar in connection with
such exchange. 
 (b)         Global Notes; Resale Restriction Termination
Date. 
 (i)         If, on the Free Trade Date, or the next succeeding
Business Day if the Free Trade Date is not a Business Day, any Initial Notes are represented by a Global Note that is a Restricted Note (any such Global Note, a “Restricted Global Note”), as promptly as practicable, the Issuer will
automatically exchange every beneficial interest in each such Restricted Global Note for beneficial interests in Global Notes that are not subject to the restrictions set forth in the Restricted Notes Legend and in Section 3.06 hereof. 

(ii)         To effect such automatic exchange, the Issuer will (A) deliver to
the Depositary an instruction letter for the Depositary’s mandatory exchange process (and/or otherwise comply with any Applicable Procedures) and (B) deliver to each of the Trustee and the Registrar a notice of the occurrence of the Free
Trade Date. Until such time as the Issuer provides such instruction letter to the Depositary notifying and confirming to the Depositary that the restricted period for the Notes has elapsed and instructing the Depositary to exchange all
“restricted securities” represented by the restricted CUSIP for “unrestricted securities” represented by an unrestricted CUSIP (and/or otherwise complies with the Applicable Procedures) and the Depositary moves the Initial Notes
from a restricted CUSIP number to an unrestricted CUSIP number in accordance with its Applicable Procedures, the restricted CUSIP will be the CUSIP number for the Initial Notes. At such time as the Issuer provides such instruction letter to the
Depositary (and/or otherwise complies with the Applicable Procedures) and the 

  
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Depositary has moved all Initial Notes represented by a restricted CUSIP number to an unrestricted CUSIP number, the Restricted Notes Legend will be deemed removed from any Global Note and an
unrestricted CUSIP number for the Initial Notes will be deemed to be the CUSIP number for the Initial Notes (the date thereof will be known as the “Resale Restriction Termination Date”). 

(iii)         Notwithstanding anything to the contrary in Sections 3.07(b)(i) or
(ii), the Issuer will not be required to effect removal of the Restrictive Notes Legend applicable to the Global Notes if it reasonably believes that removal of the Restricted Notes Legend or the changes to the CUSIP numbers for the Notes could
result in or facilitate transfers of the Notes in violation of applicable law; provided, however that the Issuer shall remain liable for Additional Interest, if any, payable pursuant to Section 4.06 for failure to remove such
Restrictive Notes Legend. 
 Section 3.08     Mutilated, Destroyed, Lost and Stolen Notes. If any mutilated
Note is surrendered to the Trustee, the Issuer shall execute and the Trustee shall authenticate and deliver in exchange therefor a new Note of like tenor and principal amount and bearing a number not contemporaneously outstanding. 

If there shall be delivered to the Issuer and the Trustee (i) evidence to their satisfaction of the destruction, loss or theft of any
Note and (ii) such security or indemnity as may be required by them to save each of them and any agent of either of them harmless, then, in the absence of notice to the Issuer or the Trustee that such Note has been acquired by a bona fide
purchaser, the Issuer shall execute and the Trustee shall authenticate and deliver, in lieu of any such destroyed, lost or stolen Note, a new Note of like tenor and principal amount and bearing a number not contemporaneously outstanding. 

In case any such mutilated, destroyed, lost or stolen Note has become or is about to become due and payable, the Issuer in its discretion may,
instead of issuing a new Note, pay such Note. 
 Upon the issuance of any new Note under this Section 3.08, the Issuer may require payment
by the Holder of a sum sufficient to cover any tax or other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith. 

Every new Note issued pursuant to this Section 3.08 in lieu of any destroyed, lost or stolen Note shall constitute an original additional
contractual obligation of the Issuer, whether or not the destroyed, lost or stolen Note shall be at any time enforceable by anyone, and shall be entitled to all the benefits of this Indenture equally and proportionately with any and all other Notes
duly issued hereunder. 
 The provisions of this Section are exclusive and shall preclude (to the extent lawful) all other rights and
remedies with respect to the replacement or payment of mutilated, destroyed, lost or stolen Notes. 

  
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 Section 3.09     Persons Deemed Owners. Prior to due presentment
of a Note for registration of transfer, the Issuer, the Guarantor, the Trustee, the Registrar and any agent of the Issuer, the Guarantor, the Trustee or the Registrar may treat the Person in whose name such Note is registered in the Register as the
owner of such Note for the purpose of receiving payment of the principal of such Note and for all other purposes whatsoever, whether or not such Note be overdue, and neither the Issuer, the Guarantor, the Trustee, the Registrar nor any agent of the
Issuer, the Guarantor, the Trustee or the Registrar shall be affected by notice to the contrary. 
 Section 3.10
    Transfer and Exchange. 
 (a)         Provisions
Applicable to All Transfers and Exchanges. 
 (i)         Subject to the
restrictions set forth in this Section 3.10, Physical Notes and beneficial interests in Global Notes may be transferred or exchanged from time to time as desired, and each such transfer or exchange will be noted by the Registrar in the Register.

 (ii)         All Notes issued upon any registration of transfer or exchange in
accordance with this Indenture will be the valid obligations of the Issuer, evidencing the same debt, and entitled to the same benefits under this Indenture as the Notes surrendered upon such registration of transfer or exchange. 

(iii)         No service charge will be imposed on any Holder of a Physical Note or
any owner of a beneficial interest in a Global Note for any exchange or registration of transfer, but each of the Issuer, the Trustee or the Registrar may require such Holder or owner of a beneficial interest to pay a sum sufficient to cover any
transfer tax, assessment or other governmental charge imposed in connection with such registration of transfer or exchange (other than exchanges pursuant to Section 3.04 not involving any transfer). 

(iv)         Unless the Issuer specifies otherwise, none of the Issuer, the Trustee,
the Registrar or any co-Registrar will be required to exchange or register a transfer of any Note (i) that has been surrendered for exchange pursuant to Article 7, (ii) as to which Section 5.06 is applicable or (iii) as to which a
Fundamental Change Repurchase Notice has been delivered and not withdrawn, except to the extent any portion of such Note is not subject to the foregoing. 

(v)         The Trustee will have no obligation or duty to monitor, determine or
inquire as to compliance with any restrictions on transfer imposed under this Indenture or under applicable law with respect to any transfer of any interest in any Note (including any transfers between or among Depositary participants or beneficial
owners of interests in any Global Note) other than to require delivery of such certificates and other documentation or evidence as are expressly required by, and to do so if and when expressly required by the terms of, this Indenture, and to examine
the same to determine substantial compliance as to form with the express requirements hereof. The Trustee shall have no responsibility whatsoever for the actions of the Depositary. 

  
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 (b)         In General; Transfer and
Exchange of Beneficial Interests in Global Notes. So long as the Notes are eligible for book-entry settlement with the Depositary, unless otherwise required by law, except to the extent required by Section 3.10(c): 

(i)         all Notes will be represented by one or more Global Notes; 

(ii)        every transfer and exchange of a beneficial interest in a Global Note
will be effected through the Depositary in accordance with the Applicable Procedures and the provisions of this Indenture (including the restrictions on transfer set forth in Section 3.06); and 

(iii)        each Global Note may be transferred only as a whole and only (A) by
the Depositary to a nominee of the Depositary, (B) by a nominee of the Depositary to the Depositary or to another nominee of the Depositary, or (C) by the Depositary or any such nominee to a successor Depositary or a nominee of such
successor Depositary. 
 (c)         Transfer and Exchange of Global
Notes. 
 (i)         Notwithstanding any other provision of this Indenture,
each Global Note will be exchanged for Physical Notes only if: 
 (A)         the
Depositary notifies the Issuer that is unwilling or unable to continue to act as Depositary for the Global Note and a successor Depositary is not appointed within 90 days; 

(B)         the Depositary is no longer registered as a clearing agency under the
Exchange Act and a successor Depositary is not appointed within 90 days; or 
 (C)
        an Event of Default has occurred and is continuing and the Depositary requests that the Physical Notes be issued in exchange for the Global Note. 

In each such case, each Global Note will be deemed surrendered to the Trustee for cancellation, and the Trustee will cause
each Global Note to be cancelled in accordance with the Applicable Procedures, and the Issuer, in accordance with Section 3.03, will promptly execute, and, upon receipt of a Company Order, the Trustee will, in accordance with Section 3.03, promptly
authenticate and deliver, for each beneficial interest in each Global Note so exchanged, an aggregate principal amount of Physical Notes equal to the aggregate principal amount of such beneficial interest, registered in such names and in such
authorized denominations as the Depositary specifies, and bearing any legends that such Physical Notes are required to bear under Section 3.06. 

  
 39 








 (ii)         In addition, if the Issuer,
in its sole discretion, determines that any beneficial interest in a Global Note will be exchangeable for Physical Notes: 

(A)         the Registrar will deliver notice of such request to the Issuer and the
Trustee, which notice will identify the aggregate principal amount of such beneficial interest and the CUSIP of the relevant Global Note; 

(B)         the Issuer will, in accordance with Section 3.03, promptly execute, and,
upon receipt of a Company Order, the Trustee, in accordance with Section 3.03, will promptly authenticate and deliver, to such owner, for the beneficial interest so exchanged by the owner of the applicable beneficial interest, Physical Notes
registered in such owner’s name having an aggregate principal amount equal to the aggregate principal amount of such beneficial interest and bearing any legends that such Physical Notes are required to bear under Section 3.06; and 

(C)         the Registrar, in accordance with the Applicable Procedures, will cause
the principal amount of such Global Note to be decreased by the aggregate principal amount of the beneficial interest so exchanged. 
 If
all of the beneficial interests in a Global Note are so exchanged, such Global Note will be deemed surrendered to the Trustee for cancellation, and the Trustee will cause such Global Note to be cancelled in accordance with the Applicable Procedures.

 (d)         Transfer and Exchange of Physical Notes. 

(i)         If Physical Notes are issued, a Holder may transfer a Physical Note by:
(A) surrendering such Physical Note for registration of transfer to the Registrar, together with any endorsements or instruments of transfer required by any of the Issuer, the Trustee or the Registrar; (B) if such Physical Note is a
Restricted Note, delivering any documentation that the Issuer, the Trustee or the Registrar reasonably requires to ensure that such transfer complies with Section 3.06 and any applicable securities laws; and (C) satisfying all other
requirements for such transfer set forth in this Section 3.10 and Section 3.06. Upon the satisfaction of conditions (A), (B) and (C), the Issuer, in accordance with Section 3.03, will promptly execute and deliver to the Trustee, and the
Trustee, upon receipt of a Company Order, will, in accordance with Section 3.03, promptly authenticate and deliver, in the name of the designated transferee or transferees, one or more new Physical Notes, of any authorized denominations, having like
aggregate principal amount and bearing any restrictive legends required by Section 3.06. 
 (ii)
        If Physical Notes are issued, a Holder may exchange a Physical Note for other Physical Notes of any authorized denominations and aggregate principal amount equal to the aggregate principal amount of
the Notes to be exchanged by surrendering such Notes, together with any endorsements or instruments of transfer required by any of the Issuer, the Trustee or the Registrar, 

  
 40 








 
at any office or agency maintained by the Issuer for such purposes pursuant to Section 4.02. Whenever a Holder surrenders Notes for exchange, the Issuer, in accordance with Section 3.03, will
promptly execute and deliver to the Trustee, and the Trustee, upon receipt of a Company Order, will, in accordance with Section 3.03, promptly authenticate and deliver the Notes that such Holder is entitled to receive, bearing registration numbers
not contemporaneously outstanding and any restrictive legends that such Physical Notes are to bear under Section 3.06. 

(iii)         If Physical Notes are issued while any Global Note is outstanding, a
Holder may transfer or exchange a Physical Note for a beneficial interest in a Global Note by (A) surrendering such Physical Note for registration of transfer or exchange, together with any endorsements or instruments of transfer required by
any of the Issuer, the Trustee or the Registrar, at any office or agency maintained by the Issuer for such purposes pursuant to Section 4.02; (B) if such Physical Note is a Restricted Note, delivering any documentation the Issuer, the
Guarantor, the Trustee or the Registrar reasonably require to ensure that such transfer complies with Section 3.06 and any applicable securities laws; (C) satisfying all other requirements for such transfer set forth in this Section 3.10 and
Section 3.06; and (D) providing written instructions to the Trustee to make, or to direct the Registrar to make, an adjustment in its books and records with respect to the applicable Global Note to reflect an increase in the aggregate principal
amount of the Notes represented by such Global Note, which instructions will contain information regarding the Depositary account to be credited with such increase; provided that no Holder of a Physical Note that is a Restricted Note may
exchange such Physical Note for an interest in a Global Note unless such Global Note is a Restricted Note subject to the same restrictions under Section 3.06 (including the same expiration of any holding periods under Rule 144) or the Issuer
otherwise consents in writing to such exchange. Upon the satisfaction of conditions (A), (B), (C) and (D), the Trustee will cancel such Physical Note and cause, or direct the Registrar to cause, in accordance with the Applicable Procedures, the
aggregate principal amount of Notes represented by such Global Note to be increased by the aggregate principal amount of such Physical Note, and will credit or cause to be credited the account of the Person specified in the instructions provided by
the exchanging Holder in an amount equal to the aggregate principal amount of such Physical Note. 
 Section 3.11
    Cancellation. The Issuer at any time may deliver to the Trustee for cancellation any Notes previously authenticated and delivered hereunder that the Issuer may have acquired in any manner whatsoever, and may deliver to
the Trustee for cancellation any Notes previously authenticated hereunder which the Issuer has not issued and sold. The Trustee shall cancel all Notes surrendered for registration of transfer, exchange, payment, purchase, repurchase, exchange
(pursuant to Article 7 hereof) or cancellation in accordance with its customary practices. If the Issuer or the Guarantor shall acquire any of the Notes, such acquisition shall not operate as a redemption or satisfaction of the indebtedness
represented by such Notes unless and until the same are delivered to the Trustee for cancellation. The Notes so acquired, while held by or on behalf of the Issuer or the Guarantor or any of its Subsidiaries,


  
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shall not entitle the Holder thereof to exchange the Notes. The Issuer may not issue new Notes to replace Notes it has paid in full or delivered to the Trustee for cancellation. The Issuer and
the Guarantor may from time to time repurchase Notes in open market purchases or negotiated transactions without giving prior notice to Holders. Any Notes repurchased by the Issuer or the Guarantor will be delivered to the Trustee for cancellation
pursuant to this Section 3.11. 
 The Registrar shall retain, in accordance with its customary procedures, copies of all letters, notices
and other written communications received pursuant to this Section 3.11. The Issuer shall have the right to inspect and make copies of all such letters, notices or other written communications at any reasonable time upon the giving of reasonable
written notice to the Registrar. 
 Section 3.12     CUSIP Numbers. In issuing the Notes, the Issuer
may use “CUSIP” numbers (if then generally in use), and, if so, the Trustee shall use “CUSIP” numbers in notices of redemption as a convenience to Holders; provided that the Trustee shall have no liability for any defect in the
CUSIP numbers as they appear on any Notes, notice, or elsewhere and; provided further, that any such notice may state that no representation is made as to the correctness of such numbers either as printed on the Notes or as contained in any notice
of a redemption and that reliance may be placed only on the other identification numbers printed on the Notes, and any such redemption shall not be affected by any defect in or omission of such numbers. The Issuer will promptly notify the Trustee in
writing of any change in the “CUSIP” numbers. 
 Section 3.13     Payment and Computation of
Interest. The Notes will bear cash interest at a rate of 2.50% per year until maturity. Interest on the Notes will accrue from the most recent date on which interest has been paid or duly provided for or, if no interest has been paid
or duly provided for, March 13, 2015. Interest will be paid semiannually in arrears on March 15 and September 15 of each year, beginning on September 15, 2015. Interest on the Notes shall be computed on the basis of a 360-day
year consisting of twelve 30-day months and, for partial months, on the basis of the number of days actually elapsed in a 30-day month. 

Section 3.14     Business Day. If any Interest Payment Date, the Maturity Date, any Fundamental Change
Repurchase Date or Redemption Date falls on a day that is not a Business Day, the required payment will be made on the next succeeding Business Day and no interest on such payment will accrue in respect of the delay. 

ARTICLE 4 
 PARTICULAR COVENANTS OF
THE ISSUER 
 Section 4.01     Payment of Principal and Interest. The Issuer will pay or cause to be
paid the principal of, Fundamental Change Repurchase Price for, Redemption Price for and any Additional Amounts with respect to, or the Exchange Obligation with respect to, and any accrued and unpaid interest on, the Notes on the dates and in the
manner required under this Indenture and the Notes. Any principal of, Fundamental Change Repurchase Price for, Redemption Price for, Additional Amounts with respect to, Exchange Obligation with respect to, or interest on, a Note will be considered
paid on the date due if the Paying Agent or in the case of an Exchange Obligation, the Exchange Agent, in each case if other than the Issuer, holds, as of 11:00 a.m., 

  
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New York City time, on the due date, money deposited by the Issuer and/or other Exchange Consideration, if applicable, in immediately available funds and designated for and sufficient to pay such
principal, Fundamental Change Repurchase Price, Redemption Price, Additional Amounts, Exchange Obligation or interest then due. Payments of the Fundamental Change Repurchase Price, Redemption Price, principal or interest (including Additional
Amounts, if any) that are not made when due will accrue interest per annum at the then-applicable interest rate from the requirement payment date. 

Section 4.02     Maintenance of Office or Agency. 

(a)         The Issuer shall maintain in the U.S. at least one office or agency of the
Exchange Agent where Notes may be presented and at least one office of the Paying Agent. In addition, the Issuer will maintain a Paying Agent and Registrar in a jurisdiction that is not obligated to withhold or deduct tax pursuant to the European
Union Directive 2003/48/EC or any other directive implementing the conclusions of the ECOFIN Council meeting of 26 and 27 November 2000 on the taxation of savings income, or any law implementing, or complying with or introduced in order to
conform to, such directive. 
 The Issuer may have one or more registrars, one or more additional paying agents and one or
more additional exchange agents. The term Paying Agent includes any additional paying agents. The term Exchange Agent includes any additional exchange agents. The term Registrar includes any additional registrars. 

(b)         The Issuer shall enter into an appropriate agency agreement with any
Registrar, Paying Agent or Exchange Agent (if other than the Trustee). The agreement shall implement the provisions of this Indenture that relate to such agent. The Issuer shall notify the Trustee in writing of the name and address of any such
agent. If the Issuer fails to maintain a Registrar, Paying Agent or Exchange Agent, the Trustee shall act as such and shall be entitled to appropriate compensation therefor pursuant to Section 11.07. The Issuer or any of its Affiliates (including
the Guarantor) may act as Paying Agent, Registrar, Exchange Agent or co-registrar. 
 (c)
        At any time, the Issuer may change such designation by delivering written notice to the Trustee signed by any officer authorized to sign an Officer’s Certificate and delivered to the Trustee,
which notice will designate some other office or agency as the Registrar, Exchange Agent or Paying Agent, as the case may be. If at any time the Issuer shall fail to maintain such office or agency or shall fail to furnish the Trustee with the
address thereof, Notes may be surrendered for exchange at the Corporate Trust Office of Trustee. 
 Section 4.03
    Appointments to Fill Vacancies in Trustee’s Office. The Issuer, whenever necessary to avoid or fill a vacancy in the office of Trustee, will appoint, in the manner provided in Section 11.11, a Trustee, so that
there shall at all times be a Trustee hereunder. 

  
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 Section 4.04     Provisions as to Paying Agent. 

(a)        The Issuer may designate additional Paying Agents, rescind the designation
of any Paying Agent, or approve a change in the office through which any Paying Agent acts. If the Issuer shall appoint a Paying Agent other than the Trustee, or if the Trustee shall appoint such a Paying Agent, the Issuer will cause such Paying
Agent to execute and deliver to the Trustee an instrument in which such agent shall agree with the Trustee, subject to the provisions of this Section 4.04: 

(i)        that it will hold all sums held by it as such agent for the payment of the
principal of (including the Fundamental Change Repurchase Price and Redemption Price, if applicable) or interest on the Notes (whether such sums have been paid to it by the Issuer or by any other obligor on the Notes) in trust for the benefit of the
Holders of the Notes; 
 (ii)        that it will give the Trustee written notice
of any failure by the Issuer or the Guarantor (or by any other obligor on the Notes) to make any payment of the principal of (including the Fundamental Change Repurchase Price and Redemption Price, if applicable) or interest on the Notes when the
same shall be due and payable; and 
 (iii)        that at any time during the
continuance of an Event of Default, upon request of the Trustee, it will forthwith pay to the Trustee all sums so held in trust. 

(b)        The Issuer shall, on or before each due date of the principal of (including
the Fundamental Change Repurchase Price and Redemption Price, if applicable) or interest on the Notes, deposit with the Paying Agent a sum (in funds which are immediately available on the due date for such payment) sufficient to pay such principal
or interest, and (unless such Paying Agent is the Trustee) the Issuer will promptly notify the Trustee of any failure to take such action; provided, however, that if such deposit is made on the due date, such deposit shall be received
by the Paying Agent by 11:00 a.m. New York City time, on such date. 
 (c)        If
the Issuer or the Guarantor shall act Paying Agent, it will, on or before each due date of the principal of (including the Fundamental Change Repurchase Price and Redemption Price, if applicable) or interest on the Notes, set aside, segregate and
hold in trust for the benefit of the Holders of the Notes a sum sufficient to pay such principal or interest so becoming due and will promptly notify the Trustee of any failure to take such action and of any failure by the Issuer or the Guarantor
(or any other obligor under the Notes) to make any payment of the principal of (including the Fundamental Change Repurchase Price and Redemption Price, if applicable) or interest on the Notes when the same shall become due and payable. 

(d)        Anything in this Section 4.04 to the contrary notwithstanding, the Issuer
may, at any time, for the purpose of obtaining a satisfaction and discharge of this Indenture, or for any other reason, pay or cause to be paid to the Trustee all sums held in 

  
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trust by the Issuer or any Paying Agent hereunder as required by this Section 4.04, such sums to be held by the Trustee upon the trusts herein contained and upon such payment by the Issuer or any
Paying Agent to the Trustee, the Issuer or such Paying Agent shall be released from all further liability with respect to such sums. 

(e)         Anything in this Section 4.04 to the contrary notwithstanding, the
agreement to hold sums in trust as provided in this Section 4.04 is subject to Section 13.03 and Section 13.04. 
 The Trustee shall not be
responsible for the actions of any other Paying Agents (including the Issuer or the Guarantor if acting as Paying Agent) and shall have no control of any funds held by such other Paying Agents. 

Section 4.05     Existence. Subject to Article 10, each of the Issuer and the Guarantor will do or cause to be
done all things necessary to preserve and keep in full force and effect its existence and rights (charter and statutory); provided, however, that the Issuer and the Guarantor shall not be required to preserve any such right if the Issuer or the
Guarantor, as applicable, shall determine that the preservation thereof is no longer desirable in the conduct of the business of the Issuer or the Guarantor, as applicable. 

Section 4.06     Additional Interest. 

(a)         If, at any time during the six-month period beginning on, and including,
the date which is six months after the last date of original issuance of any of the Initial Notes, the Guarantor fails to have timely filed any document or report that the Guarantor is required to file with the Commission pursuant to Section 13
or 15(d) of the Exchange Act, as applicable (after giving effect to all applicable grace periods thereunder and other than reports on Form 8-K), or the Initial Notes are not otherwise Freely Tradable, the Issuer shall pay Additional Interest on the
Initial Notes. Additional Interest shall accrue at the rate of 0.50% per annum of the principal amount of the Initial Notes for each day during such period for which the Guarantor’s failure to file has occurred and is continuing. 

(b)         Further, if, and for so long as, the Restrictive Notes Legend has not been
removed from the Initial Notes, the Initial Notes are assigned a restricted CUSIP number or the Initial Notes are not otherwise Freely Tradable as of the 370th day after the last date of original issuance of any of the Initial Notes, the Issuer
shall pay Additional Interest on the Initial Notes. Such Additional Interest will accrue on the Initial Notes from the 371st day after the last date of original issuance of any of the Initial
Notes at the rate of 0.50% per annum of the principal amount of Initial Notes outstanding until the Restrictive Notes Legend has been removed, the Initial Notes are assigned an unrestricted CUSIP number and the Initial Notes are Freely Tradable
(other than the Issuer’s or the Guarantor’s Affiliates or Holders that were the Issuer’s or the Guarantor’s Affiliates during the three months immediately preceding). 

(c)         Notwithstanding the foregoing, if the Issuer has complied with all
applicable requirements of the Depositary (including all applicable notice requirements) 

  
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to effect the removal of the Restrictive Notes Legend as set forth in Section 3.07 on or prior to the 370th day after the last date of original issuance of the Initial Notes, any Additional
Interest that the Issuer would otherwise be required to pay pursuant to this Section 4.06 for failure to remove the Restrictive Notes Legend will not accrue until the tenth calendar day after such 370th day. 

(d)         In no event shall Additional Interest payable pursuant to this Section
4.06 accrue, together with any Additional Interest payable pursuant to Section 9.04(b), at a rate per year in excess of 0.50% per annum, regardless of the number of events or circumstances giving rise to requirements to pay such Additional
Interest pursuant to this Section 4.06 or pursuant to Article 9. 
 (e)
        Additional Interest that is payable pursuant to this Section 4.06 shall be payable in arrears on each Interest Payment Date following accrual in the same manner as regular interest on the Notes and
shall be separate and distinct from, and in addition to, any Additional Interest that may accrue at the Issuer’s election as the sole remedy relating to a Reporting Default. 

(f)         The Issuer shall notify the Trustee and the Paying Agent (if other than
the Trustee) in writing of any Additional Interest that has become due and payable. Such notice shall include reference to the event that caused the Additional Interest to become due, the Additional Interest rate, and the date that such Additional
Interest shall begin to accrue from. If Additional Interest shall cease to accrue, the Issuer shall notify the Trustee and the Paying Agent (if other than the Trustee) in writing. 

(g)         Notwithstanding the foregoing, the Issuer will not be required to pay
Additional Interest with respect to any failure to timely file any report, if the Notes are not eligible for resale under Rule 144 or if the Notes are not Freely Tradable, in each case as required under this Section 4.06 (i) on any date on
which (a) the Issuer and the Guarantor have filed a Shelf Registration Statement for the resale of the Notes (including the Guarantee) and any Ordinary Shares issuable upon exchange of the Notes, (b) such Shelf Registration Statement is
effective and usable by Holders identified therein as selling security holders for the resale of the Notes, the Guarantee and any Ordinary Shares issued upon exchange of the notes, (c) the Holders may register the resale of their Notes under
such Shelf Registration Statement on terms customary for the resale of exchangeable securities offered in reliance on Rule 144A and (d) the Notes and/or Ordinary Shares sold pursuant to such Shelf Registration Statement become Freely Tradable
as a result of such sale, or (ii) once the Issuer has complied with the requirements set forth in clause (i) above for a period of two years. 

Section 4.07     Rule 144A Information Requirement and Annual Reports. The Issuer covenants that any annual or
quarterly reports (on Form 10-K or Form 10-Q or any successor form) that the Guarantor is required to file with the Commission pursuant to Section 13 or 15(d) of the Exchange Act (excluding any such information, documents or reports, or
portions thereof, subject to confidential treatment) shall be filed by the Issuer with the Trustee within 15 calendar days after the same are required to be filed with the Commission (giving effect to any grace period provided by Rule 12b-25 or any
successor rule under the Exchange Act); provided that in 

  
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each case the delivery of materials to the Trustee by electronic means or filing of documents pursuant to the Commission’s “EDGAR” system (or any successor thereto) shall be deemed
to constitute “filing” with the Trustee for purposes of this Section 4.07; provided, however, that the Trustee shall have no obligation whatsoever to determine if such reports have been filed. Delivery of such reports, information and
documents to the Trustee is for informational purposes only and the Trustee’s receipt of such shall not constitute constructive notice of any information contained therein or determinable from information contained therein, including the
Issuer’s or the Guarantor’s compliance with any of its covenants hereunder (as to which the Trustee is entitled to rely exclusively on Officer’s Certificates). 

At any time the Guarantor is not subject to Section 13 or 15(d) of the Exchange Act, the Issuer shall, so long as any of the Notes or
Ordinary Shares delivered upon exchange of the Notes will, at such time, constitute “restricted securities” within the meaning of Rule 144(a)(3) under the Securities Act, promptly provide to the Trustee and will, upon written request,
provide to any Holder, beneficial owner or prospective purchaser of such Notes or such Ordinary Shares, as applicable, the information required to be delivered pursuant to Rule 144A(d)(4) under the Securities Act to facilitate the resale of such
Notes or such Ordinary Shares, as applicable, pursuant to Rule 144A. 
 Section 4.08     Stay; Extension and
Usury Laws. Each of the Issuer and the Guarantor covenants (to the extent that it may lawfully do so) that it shall not at any time insist upon, plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension or
usury law or other law which would prohibit or forgive the Issuer or the Guarantor from paying all or any portion of the principal of (including the Fundamental Change Repurchase Price and Redemption Price, if applicable) or interest on the Notes as
contemplated herein, wherever enacted, now or at any time hereafter in force, or which may affect the covenants or the performance of this Indenture and each of the Issuer and the Guarantor (to the extent it may lawfully do so) hereby expressly
waives all benefit or advantage of any such law, and covenants that it will not, by resort to any such law, hinder, delay or impede the execution of any power herein granted to the Trustee, but will suffer and permit the execution of every such
power as though no such law had been enacted. 
 Section 4.09     Compliance Certificate. The Issuer shall
deliver to the Trustee, within one hundred twenty (120) days after the end of each fiscal year of the Issuer (commencing with the fiscal year ending December 31, 2015), an Officer’s Certificate, indicating whether the signer thereof
knows of any Default or Event of Default that occurred during the previous fiscal year and specifying all such Defaults or Events of Default, the nature and the status thereof and the actions which the Issuer proposes to take with respect thereto.

 The Issuer shall deliver to the Trustee, within 30 days after the Issuer becomes aware of the occurrence of any Default or Event of
Default, a written notice of such Default or Event of Default, its status and the action which the Issuer is taking or proposing to take with respect thereof; provided that the Issuer shall not be required to deliver such notice if such Default or
Event of Default has been cured. 
 Section 4.10     Additional Amounts. All payments and deliveries made by
or on behalf of the Issuer or the Guarantor, or any successor to the Issuer or the Guarantor under or with respect 

  
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to the Notes, including, but not limited to, payments of principal (including the Fundamental Change Repurchase Price and Redemption Price, if applicable), premium, if any, payments of interest
and payments of cash and/or deliveries of Ordinary Shares (together with payments of cash for any fractional Ordinary Share) upon exchange and any payments under the Guarantee pursuant to Article 15, shall be made without withholding or deduction
for, or on account of, any present or future taxes, duties, assessments or governmental charges of whatever nature imposed or levied (including any penalties and interest related thereto) (“Applicable Taxes”) by or within
(1) the Republic of Ireland (meaning Ireland exclusive of Northern Ireland) or Bermuda or any political subdivision or taxing authority thereof or therein, (2) any jurisdiction in which the Issuer or the Guarantor or any of their
successors are, for tax purposes, incorporated, organized or resident, or as a result of activities carried on by the Issuer, the Guarantor or any successor, has otherwise created a taxable presence (or any political subdivision or taxing authority
thereof or therein) or (3) any jurisdiction through which payment is made or deemed made (or any political subdivision or taxing authority thereof or therein) (each jurisdiction described in (1), (2) or (3), as applicable, a
“Relevant Taxing Jurisdiction”), unless such withholding or deduction is required by law or by the interpretation or administration thereof. In the event that any such withholding or deduction is so required, the Issuer or the
Guarantor, as appropriate, shall pay to the Holder of each Note such additional amounts (the “Additional Amounts”) as may be necessary to ensure that the net amount received by the beneficial owner after such withholding or
deduction (and after deducting any Applicable Taxes on the Additional Amounts) will equal the amounts that would have been received by such beneficial owner had no such withholding or deduction been required; provided that no additional amounts will
be payable: 
 (i)        for or on account of: 

(A)        any Applicable Taxes that would not have been imposed but for: 

(1)         the existence of any present or former connection between the relevant
Holder or beneficial owner of such Note and the Relevant Taxing Jurisdiction (other than merely acquiring or holding such Note or the receipt of payments or the exercise or enforcement of rights under the Notes or the Guarantee), including, without
limitation, such Holder or beneficial owner being or having been a national, domiciliary or resident of, or incorporated in, such Relevant Taxing Jurisdiction or treated as a resident thereof or being or having been physically present or engaged in
a trade or business therein or having had a permanent establishment therein; 
 (2)
        the presentation of such Note (in cases in which presentation is required) more than 30 days after the later of the date on which the payment of the principal of (including the Fundamental Change
Repurchase Price and Redemption Price, if applicable), premium, if any, and interest on or payments of cash and/or deliveries of Ordinary Shares upon exchange of, such Note became due and payable pursuant to the terms thereof or was made


  
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or duly provided for (except to the extent that the Holder or beneficial owner would have been entitled to Additional Amounts had the Note been presented on the last day of such 30 day period);
or 
 (3)         the failure of the Holder or beneficial owner to provide a
declaration of non-residence or other similar claim for exemption or to present any applicable form or certificate, in each case, within, a reasonable period of time following a timely and reasonable written request from the Issuer; provided
that the Holder or beneficial owner is legally entitled to provide such declaration, claim form or certificate and that upon the making of such declaration or claim or presentation of such form or certificate, the Holder or beneficial owner would
have been able to avoid such deduction or withholding; 
 (B)         any estate,
inheritance, gift, sale, transfer, personal property or similar Applicable Taxes; 
 (C)
        any Applicable Taxes that are payable otherwise than by withholding or deduction from payments under or with respect to the Notes; 

(D)         any tax imposed on a payment to an individual and required to be made
pursuant to European Council Directive 2003/48/EC on the taxation of savings income or any law implementing or complying with, or introduced in order to conform to, such directive; 

(E)         any taxes payable by or on behalf of a Holder who would have been able to
avoid such withholding or deduction by presenting the Notes or request for payment under the Guarantee to another Paying Agent designated by the Issuer pursuant to this Indenture; and 

(F)         any combination of Applicable Taxes referred to in the preceding clauses
(A), (B), (C), (D) and (E), 
 (ii)        with respect to any payment of the
principal of (including the Fundamental Change Repurchase Price and Redemption Price, if applicable), premium, if any, and interest on, or payments of cash and/or deliveries of Ordinary Shares upon exchange of such Note to a Holder, if the Holder is
a fiduciary, partnership or person, other than the sole beneficial owner of that payment, to the extent that such payment would be required under the laws of the Relevant Taxing Jurisdiction to be included for tax purposes in the income of a
beneficiary or settlor with respect to the fiduciary, a member of that partnership or a beneficial owner who would not have been entitled to such Additional Amounts had that beneficiary, settlor, partner or beneficial owner been the Holder thereof.


  
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 In addition to the foregoing, the Issuer shall also pay and indemnify the Holder for any present
or future stamp, issue, registration, value added, court or documentary taxes, or any other excise or property taxes, charges or similar levies or taxes (including penalties, interest and any other reasonable expenses related thereto) which are
levied by any Relevant Taxing Jurisdiction (“Transfer Taxes”) on the execution, delivery, registration or enforcement of any of the Notes, the Indenture or any other document or instrument referred to therein or the receipt of
payments with respect thereto. For the avoidance of doubt, the indemnification provided in this paragraph shall not include any Transfer Taxes arising from the transfer of Notes in the ordinary course. 

If the Issuer or the Guarantor become after the Issue Date obligated to pay Additional Amounts with respect to any payment under or with
respect to the Notes, the Issuer shall deliver to the Trustee on a date that is at least 30 days prior to the date of that payment (unless the obligation to pay Additional Amounts arises after the 30th day prior to that payment date, in which case
the Issuer shall notify the Trustee promptly thereafter) an Officer’s Certificate stating the fact that Additional Amounts will be payable and the amount estimated to be so payable. The Officer’s Certificate must also set forth any other
information reasonably necessary to enable the Paying Agent or the Exchange Agent, as the case may be, to pay Additional Amounts to Holders on the relevant payment date. The Trustee shall be entitled to rely solely on such Officer’s Certificate
as conclusive proof that such payments are necessary. The Issuer shall provide the Trustee with documentation reasonably satisfactory to the Trustee evidencing the payment of Additional Amounts. 

The Issuer or the Guarantor, as appropriate, shall make all withholdings and deductions required by law and shall remit the full amount
deducted or withheld to the Relevant Taxing Authority in accordance with applicable law. Upon request, the Issuer shall provide to the Trustee an official receipt or, if official receipts are not obtainable, other documentation reasonably
satisfactory to the Trustee evidencing the payment of any Applicable Taxes so deducted or withheld. The Issuer will attach to each certified copy or other document a certificate stating the amount of such Applicable Taxes paid per $1,000 principal
amount of the Notes then outstanding. Upon written request, copies of those receipts or other documentation, as the case may be, shall be made available by the Trustee to the Holders of the Notes. 

Whenever there is mentioned in any context the payment of cash and/or the delivery of Ordinary Shares (together with payments of cash for
fractional Ordinary Shares) upon exchange of the Notes or the payment of principal of (including Fundamental Change Repurchase Price and Redemption Price, if applicable), and any premium or interest, on, any Note or any other amount payable with
respect to such Note, such mention shall be deemed to include payment of Additional Amounts provided for in the Indenture to the extent that, in such context, Additional Amounts are, were or would be payable in respect thereof. 

The above obligations in this Section 4.10 will apply mutatis mutandis to any successor to the Issuer or the Guarantor. 

Section 4.11     Listing of the Notes. The Issuer will use its commercially reasonable efforts to
procure the listing of the Notes on the Global Exchange Market operated by and under the supervision of the Irish Stock Exchange (or on another recognized stock exchange for the purposes of Section 64 of the Taxes Consolidation Act 1997 of
Ireland, as amended) prior to 

  
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March 15, 2015. Additionally, the Issuer will use its commercially reasonable efforts to maintain the listing of the Notes on the Global Exchange Market operated under the supervision of the
Irish Stock Exchange or on another recognized stock exchange for the purposes of Section 64 of the Taxes Consolidation Act 1997 of Ireland. Notwithstanding the foregoing, in the event that no withholding or deduction for or on account of
Applicable Taxes by a Relevant Taxing Jurisdiction is reasonably expected to be required on payments and/or deliveries on the Notes if the Notes are not so listed on any such recognized stock exchange, the Issuer will be under no obligation to so
list (or maintain the listing of) them on any such recognized stock exchange. The Issuer shall promptly notify the Trustee in writing when the Notes are listed on any stock exchange and of any delisting thereof. 

ARTICLE 5 
 REDEMPTION 

Section 5.01    Optional Redemption. 

(a)        Optional Redemption for Changes in the Tax Laws of a Relevant Taxing
Jurisdiction. 
 (i)         Prior to March 15, 2022, if the Issuer or the
Guarantor has, or on the next Interest Payment Date would, become obligated to pay to any Holder Additional Amounts as a result of any change or amendment that is announced or becomes effective on or after the date of the Offering Memorandum in the
laws or any rules or regulations of a Relevant Taxing Jurisdiction or any change that is announced on or after the date of the Offering Memorandum in an interpretation, administration or application of such laws, rules or regulations by any
legislative body, court, governmental agency, taxing authority or regulatory or administrative authority of such Relevant Taxing Jurisdiction (including the enactment of any legislation and the formal announcement or publication of any judicial
decision or regulatory or administrative interpretation or determination) (a “Change in Tax Law”), the Issuer may at its option redeem for cash all but not part of the Notes then outstanding (except in respect of Excluded Holders
that have complied with Section 5.03(b)) at a redemption price (the “Tax Redemption Price”) equal to 100% of the principal amount plus accrued and unpaid interest to, but excluding, the Tax Redemption Date, including, for the
avoidance of doubt, any Additional Amounts with respect to such Tax Redemption Price (such redemption, a “Tax Redemption”); provided, that the Issuer may only elect a Tax Redemption if (x) the Issuer or the Guarantor (as
applicable) cannot avoid these obligations by taking commercially reasonable measures available to the Issuer or the Guarantor (as applicable), and (y) the Issuer delivers to the Trustee an opinion of outside legal counsel of recognized
standing in the Relevant Taxing Jurisdiction attesting to such Change in Tax Law and obligation to pay Additional Amounts (which opinion, for the avoidance of doubt, shall not be required to include an opinion as to whether “commercially
reasonable efforts” could be undertaken to avoid the otherwise applicable obligations) and an Officer’s Certificate attesting to such Change in Tax Law and obligation to pay Additional Amounts. If the Tax Redemption Date occurs after a
Regular Record Date and on or prior to the 

  
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corresponding Interest Payment Date, the Issuer will pay the full amount of accrued and unpaid interest and any Additional Amounts with respect to such interest, due on such Interest Payment Date
to the record Holder of the Notes on the Regular Record Date corresponding to such Interest Payment Date, and the Tax Redemption Price payable to the Holder that presents a Note for Tax Redemption will be equal to 100% of the principal amount of
such Notes, including, for the avoidance of doubt, any Additional Amounts with respect to such Tax Redemption Price. 

(ii)         Notwithstanding anything to the contrary herein, (i) the Issuer may
not redeem the Notes in the case that Additional Amounts are, or as a result of a Change in Tax Law would be, payable in respect of Irish withholding tax if no Additional Amounts would be payable if the Notes were listed on a recognized stock
exchange for Irish tax purposes on the next Interest Payment Date and (ii) no Notice of Tax Redemption shall be given earlier than 90 days prior to the earliest date on which the Issuer would, but for such Tax Redemption, be obligated to make
payments of Additional Amounts and at the time any such Notice of Tax Redemption is given, such obligation to pay such Additional Amounts must remain in effect. 

(b)        Provisional Redemption on or after March 20, 2019. On or
after March 20, 2019, the Issuer may redeem for cash all or any portion of the Notes then outstanding if the Last Reported Sale Price of the Ordinary Shares has been at least 130% of the Exchange Price then in effect for at least 20 Trading
Days (whether or not consecutive) during any 30 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the date on which the Issuer provides a Notice of Provisional Redemption. The redemption price (the
“Provisional Redemption Price”) will be equal to 100% of the principal amount of the Notes to be redeemed, plus accrued and unpaid interest to, but not including, the Provisional Redemption Date (such redemption, a
“Provisional Redemption”); provided that if the Provisional Redemption Date occurs after a Regular Record Date and on or prior to the corresponding Interest Payment Date, the Issuer will pay the full amount of accrued and
unpaid interest due on such Interest Payment Date to the record Holder of the Notes on the Regular Record Date corresponding to such Interest Payment Date, and the Provisional Redemption Price payable to the Holder who presents a Note for
Provisional Redemption will be equal to 100% of the principal amount of such Notes. 

(c)        No Notes may be redeemed in a Tax Redemption or a Provisional Redemption if
the principal amount of the Notes has been accelerated, and such acceleration has not been rescinded, on or prior to the applicable Redemption Date (except in the case of an acceleration resulting from a Default by the Issuer in the payment of the
applicable Redemption Price with respect to such date). 
 Section 5.02     Notice of Tax Redemption and Notice
of Provisional Redemption. 
 (a)        At least 60 calendar days but not more
than 70 calendar days prior to a Redemption Date in connection with a Tax Redemption or a Provisional Redemption, the 

  
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Issuer shall provide (or cause the Trustee to provide) a written notice of redemption to each Holder of Notes to be redeemed (a “Notice of Tax Redemption” or a “Notice of
Provisional Redemption,” as applicable). As long as the Notes are held through the Depositary, such notice may be made by electronic transmission to the Depositary, as registered holder. 

The Notice of Tax Redemption and the Notice of Provisional Redemption shall specify the Notes to be redeemed and shall state:

 (i)         the Redemption Date (which must be a Business Day); 

(ii)        the Redemption Price; 

(iii)        the applicable Exchange Rate and any adjustments to the Exchange Rate;

 (iv)        the applicable Exchange Price; 

(v)        the name and address of the Paying Agent and the Exchange Agent; 

(vi)        that Notes to be redeemed may be exchanged at any time before the Close
of Business on the second Scheduled Trading Day immediately preceding the Redemption Date or, if the Issuer fails to pay the Redemption Price, such later date on which the Issuer pays the Redemption Price; 

(vii)        that Holders who want to exchange Notes must satisfy the requirements
set forth therein and in this Indenture; 
 (viii)        in the case of a Tax
Redemption, that Holders have the right to elect not to have their Notes redeemed by delivery to the Paying Agent a Notice of Tax Redemption Election; 

(ix)        in the case of a Tax Redemption, that Holders who wish to elect not to
have their Notes redeemed or to withdraw such an election must satisfy the requirements set forth herein and in the Indenture; 

(x)        in the case of a Tax Redemption, that, at and after the Tax Redemption
Date, Holders who elect not to have their Notes redeemed will not receive any Additional Amounts on any payments with respect to such Notes solely as a result of the Change in Tax Law that resulted in the obligation to pay such Additional Amounts
(whether upon exchange, required repurchase in connection with a Fundamental Change, upon any subsequent Provisional Redemption, maturity or otherwise, and whether in cash, Ordinary Shares, Reference Property or otherwise) after the Tax Redemption
Date (or, if the Issuer fails to pay the Tax Redemption Price, such later date on which the Issuer pays the Tax Redemption Price), and all future payments with respect to such Notes will be subject to the deduction or withholding of such Relevant
Taxing 

  
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Jurisdiction taxes required by law to be deducted or withheld as a result of such Change in Tax Law; provided that, notwithstanding the foregoing, if a Holder electing not to have its
Notes redeemed exchanges its Notes, the Issuer shall be obligated to pay such Additional Amounts, if any, with respect to such exchange; 

(xi)         that Notes to be redeemed must be surrendered to the Paying Agent for
cancellation to collect the Redemption Price; 
 (xii)         that, unless the
Issuer defaults in making payment of such Redemption Price, interest will cease to accrue with respect to redeemed Notes on and after the Redemption Date; 

(xiii)         the CUSIP number of the Notes; 

(xiv)         in the case of a Tax Redemption, if Holders would be entitled to
Additional Shares upon exchange in connection with such redemption, that Holders would be so entitled and a description of the method for determining the amount by which the Exchange Rate has been, or would be, so increased (along with a description
of how such increase is calculated and the time period during which Notes must be surrendered in order to be entitled to such increase); and 

(xv)         if fewer than all the outstanding Notes are to be redeemed pursuant to a
Provisional Redemption, the certificate numbers (if such Notes are held other than in global form) and principal amounts of the particular Notes to be redeemed. 

(b)        Simultaneously with providing such Notice of Tax Redemption or Notice of
Provisional Redemption, as applicable, the Issuer shall publish a notice containing this information on the Guarantor’s website or through such other public medium as the Issuer may use at that time and will file the announcement with the Irish
Stock Exchange (or such other recognized stock exchange for the purposes of Section 64 of the Taxes Consolidation Act 1997 of Ireland, as amended) as long as the Notes are so listed. 

(c)        At the Issuer’s written request delivered at least 5 Business Days
prior to the Redemption Notice Date (unless a shorter period shall be acceptable to the Trustee), the Trustee shall give such Notice of Tax Redemption or Notice of Provisional Redemption, as applicable, as prepared by the Issuer, to each Holder of
Notes to be redeemed in the Issuer’s name and at the Issuer’s expense. 
 Section 5.03
    Holder’s Right to Elect in Connection with a Tax Redemption. 
 (a)
        Upon receiving a Notice of Tax Redemption, each Holder shall have the right to elect to not have its Notes redeemed, in which case the Issuer will not be obligated to pay any Additional Amounts on any
payment with respect to such Notes solely as a result of the Change in Tax Law that resulted in the obligation to pay such Additional Amounts (whether upon exchange, required repurchase in connection with a Fundamental Change, upon any subsequent
Provisional Redemption, maturity or otherwise, and whether in cash, Ordinary Shares, Reference Property or otherwise) after the Tax Redemption Date (or, if the Issuer fails to pay the Tax Redemption Price on the


  
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Tax Redemption Date, such later date on which the Issuer pays the Tax Redemption Price), and all future payments with respect to such Notes will be subject to the deduction or withholding of such
Relevant Taxing Jurisdiction taxes required by law to be deducted or withheld as a result of such Change in Tax Law; provided that, notwithstanding the foregoing, if a Holder electing not to have its Notes redeemed exchanges its Notes, the
Issuer shall be obligated to pay Additional Amounts, if any, with respect to such exchange. 
 (b)
        Upon receiving a Notice of Tax Redemption, each Holder who does not wish to have the Issuer redeem its Notes pursuant to this Article 5 (any such Holder, an “Excluded Holder”) must
deliver to the Paying Agent a written notice of election (the “Notice of Tax Redemption Election”) substantially in the form of Exhibit B hereto, or any other form of written notice substantially similar to the Notice of Tax
Redemption Election, in each case, duly completed and signed, so as to be received by the Paying Agent prior to the Close of Business on the second Scheduled Trading Day immediately preceding the Tax Redemption Date; provided that, a Holder
that complies with the requirements for exchange set forth under Section 7.02 will be deemed to have delivered a Notice of Tax Redemption Election. A Holder may withdraw any Notice of Tax Redemption Election (other than such a deemed Notice of Tax
Redemption Election) by delivering to the Paying Agent a written notice of withdrawal prior to the Close of Business on the second Scheduled Trading Day immediately preceding the Redemption Date (or, if the Issuer fails to pay the Tax Redemption
Price on the Tax Redemption Date, such later date on which the Issuer pays the Tax Redemption Price). If no such election is made or deemed to have been made, the Holder will have its Notes redeemed without any further action. 

Section 5.04     Effect of Notice of Tax Redemption and Notice of Provisional Redemption. Once a Notice of Tax
Redemption or a Notice of Provisional Redemption is given, Notes to be redeemed become due and payable on the Redemption Date and at the Redemption Price stated in such notice, except for Notes which are exchanged pursuant to Article 7 and except
for Notes subject to Section 5.03. Upon surrender to the Paying Agent, such redeemed Notes shall be paid at the Redemption Price stated in the Notice of Tax Redemption or Notice of Provisional Redemption, as applicable. Failure to give the Notice of
Tax Redemption or Notice of Provisional Redemption or any defect in such notice to any Holder shall not affect the validity of such notice to any other Holder. 

Section 5.05     Deposit of Redemption Price. Prior to 11:00 a.m. (New York City time) on a Redemption Date,
the Issuer or the Guarantor shall deposit with the Paying Agent (or if the Issuer or the Guarantor is the Paying Agent, it shall segregate and hold in trust) money sufficient to pay the Redemption Price of all Notes to be redeemed on that date other
than Notes or portions of Notes to be redeemed which on or prior thereto have been delivered by the Issuer to the Trustee for cancellation or have been exchanged. The Paying Agent shall as promptly as practicable return to the Issuer or the
Guarantor any money not required for that purpose because of exchange of Notes pursuant to Article 7. If such money is then held by the Issuer or the Guarantor in trust and is not required for such purpose it shall be discharged from such trust.


  
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 If the Paying Agent holds money sufficient to pay the Redemption Price with respect to any Notes
(i) for which a Notice of Tax Redemption has been given and with respect to which a Notice of Tax Redemption Election has not been made or deemed to have been made or (ii) for which a Notice of Provisional Redemption has been given, then,
immediately on and after the Redemption Date, interest on such Notes shall cease to accrue whether or not the Notes are delivered to the Paying Agent, and all other rights of the Holders of such Notes shall terminate, other than the right to receive
the Redemption Price of such Note, including Additional Amounts, if any, with respect thereto. Nothing herein shall preclude the withholding of any taxes required by law to be withheld or deducted. 

Section 5.06     Notes Redeemed in Part. If the Issuer elects to redeem fewer than all of the outstanding
Notes in connection with a Provisional Redemption, the Trustee will select the Notes to be redeemed (such that the principal amount of a Holder’s Note not to be redeemed equals $200,000 or an integral multiple of $1,000 in excess thereof) by
lot, or on a pro rata basis, in all cases in accordance with the Applicable Procedures. Upon surrender of a Note that is redeemed in part pursuant to a Provisional Redemption, the Issuer shall execute, and the Trustee shall authenticate and deliver
to the Holder, a new Note in an authorized denomination, which shall be $200,000 principal amount or an integral multiple of $1,000 in excess thereof, equal in principal amount to the unredeemed portion of the Note surrendered. In the event of a Tax
Redemption or Provisional Redemption, the Issuer shall not be required to (i) issue, register the transfer of or exchange any Notes during the 15 calendar day period prior to the date on which the relevant Notice of Tax Redemption or Notice of
Provisional Redemption is deemed to have been given to all Holders of Notes to be redeemed or (ii) register the transfer of or exchange any Notes so selected for redemption, in whole or in part, except the unredeemed portion of any Notes being
redeemed in part pursuant to a Provisional Redemption. 
 If the Trustee selects a portion of a Holder’s Notes for Provisional
Redemption and the Holder exchanges a portion of such Holder’s Notes, the exchanged portion of such Holder’s Notes shall be deemed to be from the portion selected for redemption, except to the extent of the excess, if any, of such
exchanged portion over such portion selected for redemption. 
 ARTICLE 6 

[RESERVED] 
 ARTICLE 7 

EXCHANGE 
 Section 7.01
    Right to Exchange. Subject to and upon compliance with the provisions of this Indenture, a Holder will have the right, at such Holder’s option, to exchange its Notes, or any portion so long as the principal amount
of such Holder’s Notes not exchanged equals $200,000 or an integral multiple of $1,000 in excess thereof, into an amount of cash, a number of Ordinary Shares or a combination of cash and Ordinary Shares, as the case may be, determined in
accordance with Section 7.03 hereof, based on the Exchange Rate (i) prior to the Close of Business on the Business Day immediately preceding December 15, 2021, only upon satisfaction of one or more of the conditions set forth in Section
7.01(a), (b), (c), (d) and (e) and (ii) on or after December 15, 2021, at any time prior to the Close of Business on the second Scheduled Trading Day immediately preceding the Maturity Date. 

  
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 (a)         Exchange upon Satisfaction
of Sale Price Condition. A Holder may surrender all or any portion of its Notes for exchange during any calendar quarter commencing after the calendar quarter ending on June 30, 2015 (and only during such calendar quarter), if
the Last Reported Sale Price of the Ordinary Shares for at least 20 Trading Days (whether or not consecutive) during the period of 30 consecutive Trading Days ending on the last Trading Day of the immediately preceding calendar quarter is greater
than or equal to 130% of the Exchange Price in effect on each applicable Trading Day. 
 (b)
        Exchange upon Satisfaction of Trading Price Condition. A Holder may surrender all or any portion of its Notes for exchange during the five Business Day period after any ten
consecutive Trading Day period (the “Measurement Period”) in which the Trading Price per $1,000 principal amount of Notes, as determined following a request by a Holder in accordance with the procedures set forth herein, for each
Trading Day of that Measurement Period was less than an amount equal to 98% of the product of (x) the Last Reported Sale Price of the Ordinary Shares on such Trading Day and (y) the applicable Exchange Rate on such Trading Day. 

The Bid Solicitation Agent (if other than the Issuer) shall have no obligation to determine the Trading Price of the Notes
unless the Issuer has requested such determination. The Issuer shall have no obligation to make such a request (or, if the Issuer is acting as Bid Solicitation Agent, the Issuer shall have no obligation to determine the Trading Price of the Notes)
unless a Holder (or beneficial holder of a Note) of at least $2.0 million principal amount provides the Issuer with reasonable evidence that the Trading Price per $1,000 principal amount of Notes would be less than 98% of the product of the Last
Reported Sale Price of the Ordinary Shares and the applicable Exchange Rate and requests that the Bid Solicitation Agent determine the Trading Price of the Notes. At such time, the Issuer shall instruct the Bid Solicitation Agent (if other than the
Issuer) to solicit, or if the Issuer is acting as Bid Solicitation Agent, the Issuer shall solicit, the secondary market bid quotations in order for the Issuer to determine the Trading Price per $1,000 principal amount of the Notes beginning on the
next Trading Day and on each successive Trading Day until the Trading Price per $1,000 principal amount of Notes is greater than or equal to 98% of the product of the Last Reported Sale Price of the Ordinary Shares and the applicable Exchange Rate.
If (x) the Issuer is not acting as the Bid Solicitation Agent, and the Issuer does not, when required, instruct the Bid Solicitation Agent to obtain bids, or if the Issuer gives such instruction to the Bid Solicitation Agent, and the Bid
Solicitation Agent fails to solicit bids, or (y) the Issuer is acting as the Bid Solicitation Agent and the Issuer fails to solicit bids when required, then, in either case, the Trading Price per $1,000 principal amount of the Notes will be
deemed to be less than 98% of the product of the Last Reported Sale Price of the Ordinary Shares and the applicable Exchange Rate on each Trading Day of such failure. 

In addition, the Issuer shall provide written notice to the Bid Solicitation Agent (if other than the Issuer) of the three
independent nationally recognized securities dealers selected by the Issuer in accordance with the definition of Trading Price, along with the appropriate contact information for each. Whenever the condition to exchange set forth in this Section
7.01(b) has been met, but was not met on the immediately preceding 

  
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Trading Day, the Issuer will so notify the Holders and the Trustee in writing. If, at any time after the condition to exchange set forth in this Section 7.01(b) has been met, the condition to
exchange set forth in this Section 7.01(b) ceases to be met, the Issuer will so notify the Holders, the Exchange Agent (if other than the Trustee) and the Trustee in writing on the first Trading Day on which the Trading Price per $1,000 principal
amount of the Notes is greater than or equal to 98% of the product of the Last Reported Sale Price of the Ordinary Shares and the Exchange Rate on such Trading Day. The Bid Solicitation Agent (if other than the Issuer), the Exchange Agent and the
Trustee shall have no obligation to determine the Trading Price of the Notes. 

(c)        Exchange upon Specified Corporate Events. 

(i)        Certain Distributions. If the Guarantor elects to: 

(A)         issue to all or substantially all holders of the Ordinary Shares rights,
options or warrants entitling such holders for a period of not more than 60 calendar days after the Issue Date of such issuance to subscribe for or purchase Ordinary Shares, at a price per Ordinary Share less than the average of the Last Reported
Sale Prices of the Ordinary Shares over the 10 consecutive Trading Day period ending on the Trading Day immediately preceding the declaration date for such issuance; or 

(B)         distribute to all or substantially all holders of the Ordinary Shares,
the Guarantor’s assets, debt securities or rights to purchase securities of the Guarantor, which distribution has a per Ordinary Share value, as reasonably determined by the Guarantor’s Board of Directors, exceeding 10% of the Last
Reported Sale Price of the Ordinary Shares on the Trading Day preceding the declaration date for such distribution, 
 then, in either
case, the Issuer shall notify in writing the Holders and the Exchange Agent not less than 45 Scheduled Trading Days prior to the Ex-Dividend Date for such issuance or distribution. Once the Issuer gives such notice, Holders may surrender their Notes
for exchange at any time until the earlier of (x) the Close of Business on the Business Day immediately preceding the Ex-Dividend Date and (y) the Guarantor’s announcement that such issuance or distribution will not take place. 

(ii)        Certain Corporate Events. 

(A)         If a transaction or event that constitutes a Fundamental Change or a
Make-Whole Fundamental Change occurs, regardless of whether a Holder has the right to require the Issuer to repurchase the Notes pursuant to Section 8.01(a) in connection with such transaction or event, all or any portion of a Holder’s Notes
may be surrendered for exchange at any time from or after the effective date of such transaction and ending on the second Scheduled Trading Day preceding the Fundamental Change Repurchase Date (in the case of transaction


  
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constituting a Fundamental Change) or the 35th Trading Day following the effective date of such transaction (in the case of a transaction that constitutes a Make-Whole Fundamental Change that is
not also a Fundamental Change). 
 (B)         If the Guarantor is a party to
(x) a consolidation, merger, binding share exchange or scheme of arrangement pursuant to which the Ordinary Shares would be exchanged into cash, securities or other assets or (y) a sale, lease or other transfer of the consolidated assets
of the Guarantor and its subsidiaries, substantially as an entirety, to another Person (other than to one or more of its direct or indirect Wholly Owned Subsidiaries prior to the Close of Business on the Business Day immediately preceding
December 15, 2021), all or any portion of a Holder’s Notes may be surrendered for exchange at any time from or after the effective date of such transaction and ending on the 35th Trading Day after the effective date of such transaction
(or, if later, until 35 Trading Days after notice of the effective date of such transaction is given following the occurrence of such transaction). The Issuer shall notify Holders, the Trustee and the Exchange Agent (if other than the Trustee) as
promptly as practicable following the date on which the Issuer publicly announces such transaction, but in no event later than the third Business Day immediately following the effective date of such transaction. 

(d)        Exchange upon Notice of Tax Redemption or Notice of Provisional
Redemption. If the Issuer has provided a Notice of Tax Redemption or a Notice of Provisional Redemption, Holders may exchange all or any portion of their Notes at any time prior to the Close of Business on the second Scheduled Trading Day
preceding the Redemption Date. After such time, a Holder’s right to exchange its Notes called for redemption will expire unless the Issuer fails to pay the Redemption Price, in which case a Holder may exchange its Notes called for redemption
until the Redemption Price is paid or duly provided for. 
 (e)        Exchange
on or after December 15, 2021. Notwithstanding the foregoing conditions set forth in this Section 7.01, on or after December 15, 2021, a Holder may exchange all or any portion of its Notes at any time prior to the Close of Business on
the second Scheduled Trading Day immediately preceding the Maturity Date. 
 Section 7.02    Exchange
Procedures. 
 (a)         General. To exercise its exchange privilege
with respect to a beneficial interest in a Global Note or with respect to a Physical Note, the Holder of such Note must: 

(i)         pay any funds required under Section 7.02(d) hereof; 

(ii)         pay any taxes or duties required under the proviso of Section 7.02(e)
hereof; and 

  
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 (iii)         if such Note is a Global
Note, (A) complete any instruction form required by the Depositary to effect the exchange of a beneficial interest under the Applicable Procedures; and (B) otherwise comply with the Applicable Procedures of the Depositary in effect on the
date such Holder seeks to exchange such beneficial interest; or 
 (iv)         if
such Note is a Physical Note, (A) complete and manually sign the exchange notice on the back of the Note (the “Exchange Notice”), or a facsimile of the Exchange Notice; (B) deliver the Exchange Notice (or facsimile
thereof), which is irrevocable, and the Note to the Exchange Agent; and, (C) if required, furnish appropriate endorsements and transfer documents. 

In addition, if a Holder has already delivered a Fundamental Change Repurchase Notice with respect to a Note in accordance with Section 8.03
hereof, except to the extent that a portion of such Note is not subject to a Fundamental Change Repurchase Notice, the Holder may not surrender that Note for exchange until the Holder has withdrawn the Fundamental Change Repurchase Notice in
accordance with Section 8.04 of this Indenture. If the Issuer has designated a Tax Redemption Date, a Holder that complies with the requirements for exchange set forth in clauses (i) through (iv) above and any other procedures required to effect an
exchange under this Indenture will be deemed to have delivered a notice of its election to not have its Notes so redeemed. 
 The first
Business Day on which a Holder complies with the relevant procedures for exchange set forth in clauses (i) through (iv) above and any other procedures required to effect a exchange under this Indenture shall be the “Exchange Date”
with respect to such Note, and, subject to Section 7.03(c), any exchange of a Note will be deemed to occur at the Close of Business on the Exchange Date applicable to such Note. If, at any time, the last date on which any Note may be exchanged is
not a Business Day, such Note may be exchanged on the immediately following Business Day. 
 (b)
        Holder of Record. If a Holder surrenders the entire principal amount of a Note for exchange, as of the Close of Business on the applicable Exchange Date, such Person will no longer be the Holder
of such Note. If any Ordinary Shares are issuable upon the exchange of a Note, except as provided under Sections 7.05(f) and 7.05(g) hereof, the Person in whose name such Ordinary Shares will be registered will become the holder of record of such
Ordinary Shares (i) if Physical Settlement applies to such Note, at the Close of Business on the Exchange Date, and (ii) if Combination Settlement applies to such Note, at the Close of Business on the last VWAP Trading Day of the relevant
Observation Period. 
 (c)         Exchanges in Part. If a Holder surrenders
only a portion of the principal amount of a Physical Note for exchange, promptly after the applicable Exchange Date, the Issuer, in accordance with Section 3.03, will execute, and the Trustee, in accordance with Section 3.03, will authenticate and
deliver to such Holder, one or more new Physical Notes, each in an authorized denomination and having an aggregate principal amount equal to the unexchanged portion of the Physical Note exchanged in part. Upon the exchange of any beneficial interest
in a Global Note, the Exchange Agent will promptly 

  
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request that the Trustee make a notation on the “Schedule of Increases and Decreases of Global Note” of such Global Note to reduce the principal amount represented by such Global Note
by the principal amount of the exchanged beneficial interest. 

(d)        Interest upon Exchange; Reimbursement of Interest upon Exchange.

 (i)        Upon exchange, a Holder shall not receive any separate cash payment
or additional Ordinary Shares for accrued and unpaid interest, if any, except as set forth below. The Issuer’s settlement of the full Exchange Obligation shall be deemed to satisfy in full its obligation to make payments in respect of the Note
being exchanged. Except as specified in clause (ii) below, accrued and unpaid interest, if any, on Notes being exchanged to, but not including, the Exchange Date, will be deemed cancelled, extinguished and forfeited. 

(ii)        Notwithstanding clause (i) above, if Holder surrenders a Note for
exchange during the period from the Close of Business on a Regular Record Date to the Open of Business on the corresponding Interest Payment Date, the Holder of such Note as of the Close of Business on the Regular Record Date will receive interest
payable on such Note on the corresponding Interest Payment Date. 
 (iii)        If
a Holder surrenders a Note for exchange during the period from the Close of Business on a Regular Record Date to the Open of Business on the corresponding Interest Payment Date, such Holder must accompany such Note with an amount of cash equal to
the amount of interest that will be payable on such Note on the corresponding Interest Payment Date; provided, however, that a Holder need not make such payment: 

(A)         if the Exchange Date follows the Regular Record Date immediately
preceding the Maturity Date; 
 (B)         if the Issuer has specified a
Redemption Date that is after a Regular Record Date and on or prior to the second Scheduled Trading Day immediately following the corresponding Interest Payment Date; 

(C)         if the Issuer has specified a Fundamental Change Repurchase Date that is
after a Regular Record Date and on or prior to the second Scheduled Trading Day immediately following the corresponding Interest Payment Date; or 

(D)         to the extent of any overdue interest, if any overdue interest exists at
the time of exchange with respect to such Note. 
 (e)         Taxes Due upon
Exchange. If a Holder exchanges a Note, the Issuer will pay any Transfer Taxes due on the issue of any Ordinary Shares upon the exchange (including any Transfer Taxes due on the issue or transfer of any Ordinary Shares represented by such
Ordinary Shares), unless the tax is due because the Holder requests that any Ordinary Shares be issued in a name other than the Holder’s name, in which case the Holder will pay that tax. 

  
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 Section 7.03     Settlement Upon Exchange. 

(a)         Settlement Methods. Except to the extent otherwise provided in
Sections 7.05(f), 7.05(h), Section 7.06(f) and 7.07 hereof, upon exchange of any Note, the Issuer shall pay or cause the delivery of, as the case may be, to the exchanging Holder, in respect of each $1,000 principal amount of Notes being exchanged,
cash (a “Cash Settlement”), Ordinary Shares, together with cash, if applicable, in lieu of any fractional Ordinary Shares (a “Physical Settlement”), or a combination of cash and Ordinary Shares, together with cash
in lieu of any fractional Ordinary Shares (a “Combination Settlement,” and each of Cash Settlement, Physical Settlement and Combination Settlement, a “Settlement Method,” and the obligation to effect such payment
and/or delivery, the “Exchange Obligation”), at the election of the Issuer, based on the Settlement Method that applies to the Note and the Exchange Rate in effect on the applicable Exchange Date, in each case, as follows: 

(i)         Physical Settlement. If the Issuer elects Physical Settlement, the
Issuer shall cause to be delivered to the exchanging Holder a number of Ordinary Shares equal to the product of (A) the aggregate principal amount of the Notes to be exchanged, divided by $1,000 and (B) the Exchange Rate in effect
on the applicable Exchange Date; provided, however, that the Issuer shall pay an amount of cash in lieu of any fractional Ordinary Shares determined in accordance with Section 7.03(a)(iv) hereof. The Issuer shall cause to be
delivered such Ordinary Shares, and pay any amount of cash in lieu of any fractional Ordinary Share, on the third Business Day immediately following the applicable Exchange Date (unless such Exchange Date is on or after the Regular Record Date
immediately preceding the Maturity Date, in which case the Issuer shall deliver the Exchange Consideration due in respect of such exchange on the Maturity Date). 

(ii)         Cash Settlement. If the Issuer elects Cash Settlement, the Issuer
shall pay to the exchanging Holder in respect of each $1,000 principal amount of the Notes being exchanged, cash in an amount equal to the sum of the Daily Exchange Values for each of the forty (40) consecutive VWAP Trading Days during the
applicable Observation Period. The Issuer shall pay such amount of cash on the third Business Day immediately following the last VWAP Trading Day of such Observation Period. 

(iii)         Combination Settlement. If the Issuer elects (or is deemed to
have elected) Combination Settlement, the Issuer shall pay or cause to be delivered, as the case may be, to the exchanging Holder in respect of each $1,000 principal amount of the Notes being exchanged, a settlement amount equal to the sum of the
Daily Settlement Amounts for each of the forty (40) consecutive VWAP Trading Days during the applicable Observation Period; provided, however, that the Issuer shall pay an amount of cash in lieu of any fractional Ordinary
Shares determined in accordance with Section 7.03(a)(iv) hereof. The Issuer shall pay or cause to be delivered, as the case may be, such settlement amount on the third Business Day immediately following the last VWAP Trading Day of such Observation
Period. 

  
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 (iv)         Fractional Ordinary
Share. If Physical Settlement or Combination Settlement applies to a Note and the Issuer’s Exchange Obligation with respect to such Note includes any fractional Ordinary Shares, in lieu of delivering such fractional Ordinary Shares, the
Issuer will pay the exchanging Holder, (A) if Physical Settlement applies to such Note, an amount of cash equal to the product of (x) such fraction of an Ordinary Share and (y) the Daily VWAP on the applicable Exchange Date (or, if
such Exchange Date is not a VWAP Trading Day, the immediately preceding VWAP Trading Day), and, (B) if Combination Settlement applies to such Note, an amount of cash equal to the product of (x) such fraction of an Ordinary Share and
(y) the Daily VWAP on the last VWAP Trading Day of the applicable Observation Period. 
 (v)
        Exchange of Multiple Notes by a Single Holder. If a Holder surrenders more than one Note for exchange on a single Exchange Date, the Issuer will calculate its Exchange Obligation with respect to
such Notes as if such Holder had surrendered for exchange one Note having an aggregate principal amount equal to the sum of the principal amounts of each of the Notes surrendered for exchange by such Holder on such Exchange Date. 

(vi)         Settlement of Accrued Interest and Deemed Payment of Principal.
Notwithstanding anything to the contrary in this Indenture, if a Holder exchanges a Note, the Issuer will not adjust the Exchange Rate to account for any accrued and unpaid interest on such Note. Except as provided in Section 7.02(d), any such
accrued and unpaid interest will be deemed cancelled, extinguished and forfeited. 
 (b)
        Issuer’s Right to Elect the Settlement Method. Except to the extent otherwise provided in Section 7.06(f) or 7.07 hereof: 

(i)         The Issuer shall use the same Settlement Method to settle every Note
having a given Exchange Date that occurs before December 15, 2021. 
 (ii)
        The Issuer shall use the same Settlement Method to settle every Note having any Exchange Date that occurs on or after December 15, 2021 and every Note having an Exchange Date after a Redemption
Notice Date and prior to the second Scheduled Trading Day preceding the related Redemption Date, in each case, regardless of whether such Notes have the same Exchange Date. 

(iii)         To elect the Settlement Method that will apply to every Note having a
given Exchange Date that occurs before December 15, 2021, on or prior to the Close of Business on the second Scheduled Trading Day immediately following such Exchange Date, the Issuer shall deliver, to each Holder exchanging a Note on such
date, through the Trustee, notice of the Settlement Method that will apply to every Note exchanged on such Exchange Date. 

(iv)         To elect the Settlement Method that will apply to every Note having an
Exchange Date on or after December 15, 2021, on or prior to the Close 

  
 63 








 
of Business on the Business Day immediately preceding December 15, 2021, the Issuer shall deliver notice of the Settlement Method that will apply to every Note having an Exchange Date on or
after December 15, 2021 to the Trustee and issue a press release containing the relevant information, make such information available on the Guarantor’s website or through such other public medium as Issuer may use at that time and file
such announcement with the Irish Stock Exchange (or such other recognized stock exchange for the purposes of Section 64 of the Taxes Consolidation Act 1997 of Ireland, as amended) as long as the Notes are listed thereon. 

(v)         To elect the Settlement Method that will apply to every Note having an
Exchange Date after a Redemption Notice Date and prior to the second Scheduled Trading Day preceding the related Redemption Date, the Issuer shall provide notice of the Settlement Method that will apply to every Note having an Exchange Date after a
Redemption Notice Date and prior to the second Scheduled Trading Day preceding the related Redemption Date in the applicable Redemption Notice. 

(vi)         Whenever the Issuer elects to settle Notes with a Combination
Settlement, the notice electing such Settlement Method must also state the Specified Dollar Amount. 
 (vii)
        If the Issuer fails to validly elect a Settlement Method (and Specified Dollar Amount, if applicable) in accordance with this Section 7.03(b) that will apply to (i) every Note having a given
Exchange Date that occurs before December 15, 2021, (ii) every Note having an Exchange Date after a Redemption Notice Date and prior to the second Scheduled Trading Day preceding the related Redemption Date or (iii) every Note having
an Exchange Date on or after December 15, 2021, as the case may be, then Combination Settlement will apply to every Note exchanged on such Exchange Date or Exchange Dates, as the case may be, and the Specified Dollar Amount for such Combination
Settlement will be deemed to equal $1,000. If the Issuer timely elects Combination Settlement, but fails to timely notify Holders of the Specified Dollar Amount, the Specified Dollar Amount shall deemed to be $1,000. 

(viii)         Prior to December 15, 2021, the Issuer will have the right to
irrevocably elect Combination Settlement with a Specified Dollar Amount equal to or greater than $1,000 by delivering written notice to the Holders, the Trustee and the Conversion Agent, issuing a press release containing the relevant information,
making such information available on the Guarantor’s website or through such other public medium as Issuer may use at that time and filing such announcement with the Irish Stock Exchange (or such other recognized stock exchange for the purposes
of Section 64 of the Taxes Consolidation Act 1997 of Ireland, as amended) as long as the Notes are listed thereon. Following such irrevocable election, the Issuer shall not have the right to change the Settlement Method; provided that it
may continue to select a Specified Dollar Amount equal to or greater than $1,000 with respect to an Exchange Date in accordance with the provisions of this Section 7.03(b). 

  
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 (ix)         Notices. Whenever an
Exchange Date occurs with respect to a Note, the Exchange Agent will, as promptly as possible, and in no event later than 11:59 a.m., New York City time, on the Scheduled Trading Day immediately following such Exchange Date, deliver to the Issuer
and the Trustee notice that an Exchange Date has occurred, which notice will state such Exchange Date, the principal amount of Notes exchanged on such Exchange Date and the names of the Holders that exchanged Notes on such Exchange Date. 

On the first Business Day immediately following the last VWAP Trading Day of the Observation Period applicable to any Exchange
Date, the Issuer will deliver written notice to the Exchange Agent and the Trustee stating (A) the Daily Settlement Amounts (if Combination Settlement applies to the Notes exchanged on such Exchange Date) or the Daily Exchange Values (if Cash
Settlement applies to the Notes exchanged on such Exchange Date), in each case, for each VWAP Trading Day in such Observation Period, and (B) the amount of cash, the number of Ordinary Shares or the amount of cash and the number of Ordinary
Shares, as the case may be, that the Issuer is obligated to pay or cause to be delivered, as the case may be, to satisfy its Exchange Obligation with respect to each Note exchanged on such Exchange Date. 

(c)        Surrender to Financial Institution in Lieu of Exchange. 

Notwithstanding the provisions described above in this Section 7.03, in satisfaction of the Exchange Obligation, the Issuer
may, at its election (a “Financial Institution Surrender Election”), direct the Exchange Agent to surrender, on or prior to the second Business Day following the Exchange Date, such Notes to a financial institution designated by the
Issuer (a “Financial Institution Surrender”) in lieu of exchange. In order to accept any Notes surrendered for a Financial Institution Surrender, the designated financial institution(s) must agree to timely deliver, in exchange for
such Notes, the cash, Ordinary Shares or combination of cash and Ordinary Shares, at the Issuer’s election, equal to the consideration due upon exchange (the “Exchange Consideration”) pursuant to this Section 7.03, as is
designated to the Exchange Agent in writing by the Issuer. If the Issuer makes a Financial Institution Surrender Election, by the Close of Business on the second Business Day following the relevant surrender date, the Issuer shall (i) notify,
in the manner provided in this Section 7.03, the Holder surrendering its Notes for exchange, the Exchange Agent (if other than the Trustee) and the Trustee, that the Issuer has made the Financial Institution Surrender Election and (ii) notify
the designated financial institution of the relevant deadline for delivery of the Exchange Consideration. If the designated financial institution accepts any such Notes, they shall deliver the Exchange Consideration in accordance with this Section
7.03. Any Notes exchanged by the designated financial institution shall remain outstanding. If the designated financial institution agrees to accept any Notes for surrender but does not timely deliver the related Exchange Consideration, or if such
designated financial institution does not accept the Notes for a Financial Institution Surrender, the Issuer shall deliver the relevant Exchange Consideration as if the Issuer had not made a Financial


  
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Institution Surrender Election. The Issuer’s designation of a financial institution to which the Notes may be submitted for a Financial Institution Surrender does not require such
institution to accept any Notes. The Issuer may, but will not be obligated to, enter into a separate agreement with any designated financial institution that would compensate it for any such transaction. 

Section 7.04     Certain Provisions Related to Ordinary Shares Issued Hereunder. 

(a)         The Guarantor shall and the Issuer shall cause the Guarantor to provide,
free from preemptive rights, out of the Guarantor’s authorized but unissued shares or shares held in treasury, sufficient Ordinary Shares to provide for exchange of the Notes from time to time as such Notes are presented for exchange (assuming
that at the time of computation of such number of Ordinary Shares, all such Notes would be converted by a single Holder and Physical Settlement applies to such Notes). 

(b)         Each of the Guarantor and the Issuer covenants that all Ordinary Shares
issued upon exchange of Notes will be fully paid and non-assessable by the Guarantor and free from all taxes, liens and charges with respect to the issue thereof. 

(c)         The Guarantor will cause any Ordinary Shares issuable hereunder (whether
upon exchange, under the terms of the Guarantee or otherwise) to be listed on whatever stock exchange(s) the Ordinary Shares are listed, if permitted and required by the rules of such stock exchange(s), on the date the exchanging Holder becomes a
record holder of such Ordinary Shares. 
 (d)         The Issuer and the Guarantor
acknowledge that the allotment and issue of Ordinary Shares and the delivery of Ordinary Shares, if any, hereunder (whether upon exchange, under the terms of the Guarantee or otherwise) by the Guarantor (or by the Ordinary Share Depositary at the
direction of the Guarantor) will create an equivalent debt owing from the Issuer to the Guarantor. For the avoidance of doubt, upon the delivery of Ordinary Shares by the Guarantor in respect of an Exchange Obligation, the portion of such Exchange
Obligation consisting of an obligation to deliver or cause to be delivered Ordinary Shares shall be deemed satisfied to the extent of the Ordinary Shares so delivered. 

(e)         The exercise by a Holder of a Note of the right to require exchange of
that Note for Ordinary Shares in compliance with the provisions of this Indenture shall be deemed to constitute a demand for immediate repayment by the Issuer of that Note. 

Section 7.05     Adjustment of Exchange Rate. 

The Issuer will adjust the Exchange Rate from time to time as described in this Section 7.05, except that the Issuer will not make any
adjustments to the Exchange Rate for any transaction described in this Section 7.05 (other than in the case of (x) a share subdivision or share consolidation or (y) a tender or exchange offer) if each Holder participates, in such
transaction at the same time and upon the same terms as holders of the Ordinary Shares and solely as a result of holding the Notes, without having to exchange its Notes and as if it held a number of Ordinary Shares equal to the applicable Exchange
Rate, multiplied by the principal amount (expressed in thousands) of Notes held by such Holder. 

  
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 (a)         Stock Dividends and Share
Splits. If the Guarantor exclusively issues Ordinary Shares as a dividend or distribution on all or substantially all of the Ordinary Shares, or if the Guarantor effects an Ordinary Share subdivision or Ordinary Share consolidation, the Exchange
Rate will be adjusted based on the following formula: 
  

															
					  

ER1
  

 
		  
  

 = 
  
		  

ER0
  

 
		  
  

× 
  
		 OS1

 
		
							OS0 		

 where: 
  

					
	ER0		=		the Exchange Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date of such dividend or distribution, or immediately prior to the Open of Business on the Effective Date of such Ordinary Share subdivision
or Ordinary Share consolidation, as applicable;
			
	ER1		=		the Exchange Rate in effect immediately after the Open of Business on such Ex-Dividend Date or Effective Date;
			
	OS0		=		the number Ordinary Shares in issue immediately prior to the Open of Business on such Ex-Dividend Date or such Effective Date; and
			
	OS1		=		the number of Ordinary Shares in issue immediately after giving effect to such dividend, distribution, Ordinary Share subdivision or Ordinary Share consolidation.

 Any adjustment made under this Section 7.05(a) shall become effective immediately after the Open of Business
on the Ex-Dividend Date for such dividend or distribution, or immediately after the Open of Business on the Effective Date for such Ordinary Share subdivision or Ordinary Share consolidation. If any dividend or distribution of the type described in
this Section 7.05(a) is declared but not so paid or made, the Exchange Rate shall be immediately readjusted, effective as of the date the Guarantor’s Board of Directors determines not to pay such dividend or distribution, to the Exchange Rate
that would then be in effect if such dividend or distribution had not been declared. 
 (b)
        Rights, Options, and Warrants. If the Guarantor issues to all or substantially all holders of Ordinary Shares any rights, options or warrants entitling such holders for a period of not more than
60 calendar days after the date of such issuance to subscribe for or purchase Ordinary Shares, at a price per Ordinary Share less than the average of the Last Reported Sale Prices of the Ordinary Shares over the 10 consecutive Trading Day period
ending on, and including, the Trading Day immediately preceding the declaration date for such issuance, the Exchange Rate will be increased based on the following formula: 
  

															
					  

ER1
  

 
		  
  

 = 
  
		  

ER0
  

 
		  
  

 ×  
  
		OS0 + X    		
							  
 OS0 + Y    
		


  
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 where: 
  

					
	ER0		=		the Exchange Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date for such issuance;
			
	ER1		=		the Exchange Rate in effect immediately after the Open of Business on such Ex-Dividend Date;
			
	OS		=		the number of Ordinary Shares in issue immediately prior to the Open of Business on such Ex-Dividend Date;
			
	X		=		the total number of Ordinary Shares issuable pursuant to such rights, options or warrants; and
			
	Y		=		the number of Ordinary Shares equal to the aggregate price payable to exercise such rights, options or warrants divided by the average of the Last Reported Sale Prices of the Ordinary Shares over the 10 consecutive Trading
Day period ending on, and including, the Trading Day immediately preceding the declaration date of such issuance.

 Any increase made under this Section 7.05(b) will be made successively whenever any such rights, options or
warrants are issued and shall become effective immediately after the Open of Business on the Ex-Dividend Date for such issuance. To the extent that Ordinary Shares are not delivered after the expiration of such rights, options or warrants, the
Exchange Rate shall be readjusted to the Exchange Rate that would then be in effect had the increase with respect to the issuance of such rights, options or warrants been made on the basis of delivery of only the number of Ordinary Shares actually
delivered. If such rights, options or warrants are not so issued, the Exchange Rate shall be readjusted to be the Exchange Rate that would then be in effect if such Ex-Dividend Date for such issuance had not occurred. 

For purposes of this Section 7.05(b) and for purposes of Section 7.01(c)(i), in determining whether any rights, options or
warrants entitle holders of Ordinary Shares to subscribe for or purchase Ordinary Shares, at a price per Ordinary Share less than such average of the Last Reported Sale Prices for the Ordinary Shares over the 10 consecutive Trading Day period ending
on, and including, the Trading Day immediately preceding the declaration date for such issuance, and in determining the aggregate offering price of such Ordinary Shares, there shall be taken into account any consideration received by the Guarantor
for such rights, options or warrants and any amount payable on exercise or exchange thereof, the value of such consideration, if other than cash, to be determined by the Guarantor’s Board of Directors. 

  
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 (c)         Spin-Offs and Other
Distributed Property. 
 (i)         If the Guarantor distributes shares of the
Guarantor’s Share Capital, evidences of its indebtedness, other assets or property of the Guarantor or rights, options or warrants to acquire the Guarantor’s Share Capital or other securities of the Guarantor (the “Distributed
Property”) to all or substantially all holders of the Ordinary Shares, excluding: 
 (A)
        dividends, distributions or issuances as to which an adjustment was effected pursuant to Section 7.05(a) hereof or Section 7.05(b) hereof; 

(B)         dividends or distributions paid exclusively in cash as to which an
adjustment was effected pursuant to Section 7.05(d) hereof; 
 (C)         any
dividends and distributions in connection with a Merger Event resulting in the change in the Exchange Consideration as described in Section 7.07; 

(D)         except as otherwise described under this Section 7.05, rights issued
pursuant to a shareholder rights plan adopted by the Guarantor; or 
 (E)
        Spin-Offs as to which the provisions of Section 7.05(c)(ii) hereof shall apply, 
 then the
Exchange Rate will be increased based on the following formula: 
  

															
					  

ER1
  

 
		  
  

 = 
  
		  

ER0
  

 
		  
  

 ×  
  
		SP0		
							  
  SP0 - FMV 
		

 where: 
  

					
	ER0		=		the Exchange Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date for such distribution;
			
	ER1		=		the Exchange Rate in effect immediately after the Open of Business on such Ex-Dividend Date;
			
	SP0		=		the average of the Last Reported Sale Prices of the Ordinary Shares over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the Ex-Dividend Date for such distribution;
and
			
	FMV		=		the fair market value (as determined by the Guarantor’s Board of Directors) of the Distributed Property distributed with respect to each outstanding Ordinary Share in issue on the Ex-Dividend Date for such
distribution.


  
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 If “FMV” (as defined above) is equal to or greater than “SP0” (as defined above), in lieu of the foregoing increase, each Holder will receive, in respect of each $1,000 principal amount of Notes it holds, at the same time and upon the same terms as
holders of the Ordinary Shares, the amount and kind of the Distributed Property that such Holder would have received if such Holder had owned a number of Ordinary Shares equal to the Exchange Rate in effect on the Ex-Dividend Date for the
distribution. 
 Any increase in the Exchange Rate made under this Section 7.05(c)(i) will become effective immediately
after the Open of Business on the Ex-Dividend Date for such distribution. If such distribution is not so paid or made, the Exchange Rate shall be readjusted to be the Exchange Rate that would then be in effect if such dividend or distribution had
not been declared. If the Guarantor issues rights, options or warrants that are only exercisable upon the occurrence of certain triggering events, then the Issuer will not adjust the Exchange Rate pursuant to this Section 7.05(c)(i) until the
earliest of those triggering events occurs. In addition, in the case of any distribution of rights, options or warrants, to the extent such rights, options or warrants expire unexercised, the Exchange Rate shall be immediately readjusted to the
Exchange Rate that would then be in effect had the increase made for the distribution of such rights, options or warrants been made on the basis of delivery of only the number of Ordinary Shares actually delivered upon exercise of such rights,
options or warrants. 
 (ii)         With respect to an adjustment pursuant to this
Section 7.05(c) where there has been a payment of a dividend or other distribution on the Ordinary Shares of shares of Share Capital of any class or series, or similar equity interest, of or relating to a Subsidiary or other business unit of the
Guarantor, and such Share Capital or similar equity interest is listed or quoted (or will be listed or quoted upon the consummation of such dividend or other distribution) on a U.S. national securities exchange or a reasonably comparable non-U.S.
equivalent (a “Spin-Off”), the Exchange Rate will be increased based on the following formula: 
  

															
					  

ER1
  

 
		  
  

 = 
  
		  

ER0
  

 
		  
  

 × 
  
		    FMV0 + MP0   
 		
							  

MP0
		

 where: 
  

					
	ER0		=		the Exchange Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date for the Spin-Off;
			
	ER1		=		the Exchange Rate in effect immediately after the Open of Business on the Ex-Dividend Date for the Spin-Off;
			
	FMV0		=		the average of the Last Reported Sale Prices of the Share Capital or similar equity interest distributed to holders of the Ordinary Shares applicable to one Ordinary Share (determined by reference to the definition of “Last
Reported Sale Price” set forth in Section 1.01 hereof as if references therein to Ordinary Shares were to such Share Capital or similar equity interest) over the first 10 consecutive Trading Day period after, and including, the Ex-Dividend Date
of the Spin-Off (the “Valuation Period”); and
			
	MP0		=		the average of the Last Reported Sale Prices of the Ordinary Shares over the Valuation Period.


  
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 The adjustment to the Exchange Rate under the preceding paragraph will be determined on the last
Trading Day of the Valuation Period, but given effect as of the Ex-Dividend Date for the Spin-Off; provided that in respect of any exchange of Notes during the Valuation Period, references in this Section 7.05(c)(ii) with respect to 10
Trading Days shall be deemed to be replaced with such lesser number of Trading Days as have elapsed between the Ex-Dividend Date of such Spin-Off and the Exchange Date in determining the Exchange Rate. If the Ex-Dividend Date of the Spin-Off is
after the 10th Trading Day immediately preceding, and including, the end of any Observation Period in respect of an exchange of Notes, references in the preceding paragraph to 10 Trading Days will be deemed to be replaced, solely in respect of that
exchange, with such lesser number of Trading Days as have elapsed from, and including, the Ex-Dividend Date for the Spin-Off to, and including, the last VWAP Trading Day of such Observation Period. 

If any dividend or distribution that constitutes a Spin-Off is not so paid, the Exchange Rate shall be decreased, effective as
of the date the Guarantor’s Board of Directors determines not to pay such dividends or distributions, to the Exchange Rate that would then be in effect if such dividend or distribution had not been declared. 

For purposes of this Section 7.05(c) (and subject in all respect to Section 7.05(h)), rights, options or warrants distributed
by the Guarantor to all holders of the Ordinary Shares entitling them to subscribe for or purchase shares of the Guarantor’s Share Capital, including the Ordinary Shares (either initially or under certain circumstances), which rights, options
or warrants, until the occurrence of a specified event or events (“Trigger Event”): (A) are deemed to be transferred with such Ordinary Shares; (B) are not exercisable; and (C) are also issued in respect of future
issuances of the Ordinary Shares, shall be deemed not to have been distributed for purposes of this Section 7.05(c) (and no adjustment to the Exchange Rate under this Section 7.05(c) will be required) until the occurrence of the earliest Trigger
Event, whereupon such rights, options or warrants shall be deemed to have been distributed and an appropriate adjustment (if any is required) to the Exchange Rate shall be made under this Section 7.05(c). If any such right, option or warrant,
including any such existing rights, options or warrants distributed prior to the date of this Indenture, are subject to events, upon the occurrence of which such rights, options or warrants become exercisable to purchase different securities,
evidences of indebtedness or other assets, then the date of the occurrence of any and each such event shall be deemed to be the Ex-Dividend Date with respect to new rights, options or warrants with such rights (in which case the existing rights,
options or warrants shall be deemed to terminate and expire on such date without exercise by any of the holders thereof). In addition, in the event of any distribution (or deemed distribution) 

  
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of rights, options or warrants, or any Trigger Event or other event (of the type described in the immediately preceding sentence) with respect thereto that was counted for purposes of calculating
a distribution amount for which an adjustment to the Exchange Rate under this Section 7.05(c) was made, (1) in the case of any such rights, options or warrants that shall all have been purchased without exercise by any holders thereof, upon
such final purchase (x) the Exchange Rate shall be readjusted as if such rights, options or warrants had not been issued and (y) the Exchange Rate shall then again be readjusted to give effect to such distribution, deemed distribution or
Trigger Event, as the case may be, as though it were a cash distribution, equal to the per share purchase price received by a holder or holders of the Ordinary Shares with respect to such rights, options or warrants (assuming such holder had
retained such rights, options or warrants), made to all holders of Ordinary Shares as of the date of such purchase, and (2) in the case of such rights, options or warrants that shall have expired or been terminated (or deemed to have expired or
been terminated pursuant to the immediately preceding sentence) without exercise by any holders thereof, the Exchange Rate shall be readjusted as if such rights, options and warrants had not been issued (to the extent any adjustment to the Exchange
Rate was made in connection with such issuance). 
 For purposes of Section 7.05(a) hereof, Section 7.05(b) hereof and this
Section 7.05(c), if any dividend or distribution to which this Section 7.05(c) applies includes one or both of: 
 (A)
        a dividend or distribution of Ordinary Shares to which Section 7.05(a) hereof also applies (the “Clause A Distribution”); or 

(B)         a dividend or distribution of rights, options or warrants to which
Section 7.05(b) hereof also applies (the “Clause B Distribution”), 
 then, in either case, (i) such dividend or
distribution, other than the Clause A Distribution and the Clause B Distribution, shall be deemed to be a dividend or distribution to which this Section 7.05(c) applies (the “Clause C Distribution”) and any Exchange Rate adjustment
required to be made under this Section 7.05(c) with respect to such Clause C Distribution shall then be made, (ii) the Clause B Distribution, if any, shall be deemed to immediately follow the Clause C Distribution and any Exchange Rate
adjustment required by Section 7.05(b) hereof with respect thereto shall then be made, except that, if determined by the Guarantor, (A) the “Ex-Dividend Date” of the Clause B Distribution and the Clause A Distribution, if any, shall
be deemed to be the Ex-Dividend Date of the Clause C Distribution and (B) any Ordinary Shares included in the Clause A Distribution or the Clause B Distribution shall not be deemed to be “outstanding immediately prior to the Open of
Business on such Ex-Dividend Date” within the meaning of Section 7.05(b) hereof, and (iii) the Clause A Distribution, if any, shall be deemed to immediately follow the Clause C Distribution or the Clause B Distribution, as the case may be,
except that, if determined by the Guarantor, (A) the “Ex-Dividend Date” of the Clause A Distribution and the Clause B Distribution, if any, shall be deemed to be the Ex-Dividend Date of the Clause C Distribution, and any Ordinary
Shares included in the Clause A distribution shall not be deemed to be “outstanding immediately prior to the Open of Business on such Ex-Dividend Date or such Effective Date within the meaning of Section 7.05(a) hereof. 

  
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 (d)         Cash Dividends or
Distributions. If any cash dividend or distribution is made to all or substantially all holders of the Ordinary Shares, the Exchange Rate will be adjusted based on the following formula: 

 

															
					  

ER1
  

 
		  
  

 = 
  
		  

ER0
  

 
		  
  

 × 
  
		      SP0      		
							  
 SP0
- C
		

 where: 
  

					
	ER0		=		the Exchange Rate in effect immediately prior to the Open of Business on the Ex-Dividend Date for such dividend or distribution;
			
	ER1		=		the Exchange Rate in effect immediately after the Open of Business on the Ex-Dividend Date for such dividend or distribution;
			
	SP0		=		the Last Reported Sale Price of the Ordinary Shares on the Trading Day immediately preceding the Ex-Dividend Date for such dividend or distribution; and
			
	C		=		the amount in cash per Ordinary Share that the Guarantor distributes to holders of the Ordinary Shares.

 If “C” (as defined above) is equal to or greater than “SP0” (as defined above), in lieu of the foregoing increase, each Holder shall receive, for each $1,000 principal amount of Notes it holds, at the same time and upon the same terms as holders of
the Ordinary Shares, the amount of cash that such Holder would have received if such Holder had owned a number of Ordinary Shares equal to the Exchange Rate on the Ex-Dividend Date for such cash dividend or distribution. Any such increase shall
become effective immediately after the Open of Business on the Ex-Dividend Date for such dividend or distribution. If such dividend or distribution is not so paid, the Exchange Rate shall be decreased to be the Exchange Rate that would then be in
effect if such dividend or distribution had not been declared. 
 (e)
        Tender Offers or Exchange Offers. If the Guarantor or any of its Subsidiaries makes a payment in respect of a tender offer or exchange offer for the Ordinary Shares, other than odd lot tender
offers, to the extent that the cash and value of any other consideration included in the payment per Ordinary Share exceeds the average of the Last Reported Sale Price of the Ordinary Shares over the 10 consecutive Trading Day period commencing on,
and including, the Trading Day next succeeding the last date on which tenders or exchanges may be made pursuant to such tender offer or exchange offer, the Exchange Rate will be increased based on the following formula: 

 

															
					  

ER1
  

 
		  
  

 = 
  
		  

ER0
  

 
		  
  

 × 
  
		    AC + (SP1 x 
OS1)    		
							  
 OS0 x SP1 
		


  
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 where: 
  

					
	ER0		=		the Exchange Rate in effect immediately prior to the Close of Business on the 10th Trading Day immediately following, and including, the Trading Day next succeeding the date
such tender offer or exchange offer expires;
			
	ER1		=		the Exchange Rate in effect immediately after the Close of Business on the 10th Trading Day immediately following, and including, the Trading Day next succeeding the date such
tender offer or exchange offer expires;
			
	AC		=		the aggregate value, on the date such tender or exchange offer expires, of all cash and any other consideration (as determined by the Guarantor’s Board of Directors) paid or payable for Ordinary Shares purchased in such
tender offer or exchange offer;
			
	OS0		=		the number of Ordinary Shares in issue immediately prior to the Close of Business on the date such tender offer or exchange offer expires (prior to giving effect to the purchase of all Ordinary Shares accepted for purchase or
exchange in such tender offer or exchange offer);
			
	OS1		=		the number of Ordinary Shares in issue immediately after the Close of Business on the date such tender offer or exchange offer expires (after giving effect to the purchase of all Ordinary Shares accepted for purchase or exchange
in such tender offer or exchange offer); and
			
	SP1		=		the average of the Last Reported Sale Prices of the Ordinary Shares over the 10 consecutive Trading Day period commencing on, and including, the Trading Day next succeeding the date such tender or exchange offer
expires.

 The adjustment to the Exchange Rate under the preceding paragraph will occur at the Close of Business on the
10th Trading Day immediately following, and including, the Trading Day next succeeding the date such tender offer or exchange offer expires; provided that in respect of any exchange of Notes within the 10 Trading Days immediately following,
and including, the Trading Day next succeeding the expiration date of any tender offer or exchange offer, references with respect to 10 Trading Days shall be deemed replaced with such lesser number of Trading Days as have elapsed between the
expiration date of such tender offer or exchange offer and the Exchange Date in determining the Exchange Rate. In addition, if the Trading Day next succeeding the date such tender offer or exchange offer expires is after the 10th Trading Day
immediately preceding, and including, the end of any Observation Period in respect of an exchange of Notes, references in the preceding paragraph to 10 Trading Days shall be deemed to be replaced, solely in respect of that exchange, with such lesser
number of 

  
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Trading Days as have elapsed from, and including, the Trading Day next succeeding the date such tender or exchange offer expires to, and including, the last VWAP Trading Day of such Observation
Period. 
 If the Guarantor or one of its Subsidiaries is obligated to purchase Ordinary shares pursuant to any such tender offer or
exchange offer described in this Section 7.05(e) but is permanently prevented by applicable law from effecting any such purchase or all such purchases are rescinded, the applicable Exchange Rate will be readjusted to be the Exchange Rate that would
then be in effect if such tender offer or exchange offer had not been made or had been made only in respect of the purchases that have been effected. 

(f)         Notwithstanding anything this Article 7, certain listing standards of The
NASDAQ Global Select Market may limit the amount by which the Issuer may increase the Exchange Rate pursuant to the events described in Sections 7.05(b) through (e) or pursuant to Section 7.06. These standards generally require the Guarantor to
obtain the approval of its shareholders before entering into certain transactions that potentially result in the issuance of 20% or more of the Ordinary Shares in issue at the time the Notes are issued unless the Guarantor obtains shareholder
approval of issuances in excess of such limitations. In accordance with these listing standards, these restrictions will apply at any time when the Notes are outstanding, regardless of whether we then have a class of securities listed on The NASDAQ
Global Select Market. Accordingly, in the event of an increase in the Exchange Rate above that which would result in the Notes, in the aggregate, becoming exchangeable into Ordinary Shares in excess of such limitations, at the Issuer’s option,
either the Guarantor will obtain shareholder approval of such issuances or the Issuer will pay cash in lieu of delivering any Ordinary Shares otherwise deliverable upon exchanges in excess of such limitations based on the Daily VWAP on the Exchange
Date (in the case of Physical Settlement) or for each Trading Day of the relevant Observation Period (in the case of Combination Settlement) in respect of which, in lieu of causing the delivery of Ordinary Shares, the Issuer pays cash pursuant to
this Section 7.05(f). 
 (g)         Special Provisions for Combination
Settlement of Certain Exchanges. Notwithstanding anything to the contrary herein, if an Exchange Rate adjustment becomes effective on any Ex-Dividend Date as described in this Section 7.05, and a Holder that has exchanged its Notes on or after
such Ex-Dividend Date and on or prior to the related Record Date would be treated as the record holder of Ordinary Shares as of the related Exchange Date based on an adjusted Exchange Rate for such Ex-Dividend Date, then, notwithstanding the
foregoing Exchange Rate adjustment provisions, the Exchange Rate adjustment relating to such Ex-Dividend Date will not be made for such exchanging Holder. Instead, such Holder will be treated as if such Holder were the record owner of Ordinary
Shares on an unadjusted basis and participate in the related dividend, distribution or other event giving rise to such adjustment. 

(h)         Rights Plan. To the extent that the Guarantor has a rights plan
applicable to the Ordinary Shares in effect upon exchange of any Notes, if Physical Settlement or Combination Settlement applies to such a Note, the exchanging Holder will receive, in addition to any Ordinary Shares received in connection with such
exchange, the rights 

  
 75 








 
under such rights plan. However, if prior to any exchange, the rights have separated from the Ordinary Shares in accordance with the provisions of the applicable rights plan, the Exchange Rate
will be adjusted at the time of separation as if the Guarantor distributed, to all or substantially all holders of the Ordinary Shares, the Distributed Property as described in clause (c)of this Section 7.05, subject to readjustment in the event of
the expiration, termination or redemption of such rights. 
 (i)         Other
Adjustments. Whenever a provision of this Indenture requires the Issuer to calculate the Last Reported Sale Prices, the Daily VWAPs, the Daily Exchange Values, the Daily Settlement Amounts or any functions thereof over a span of multiple days
(including, without limitation, during an Observation Period and, if applicable, during the 5 Trading Day period used to determine the Ordinary Share Price), the Issuer will make appropriate adjustments (to the extent no corresponding adjustment is
otherwise made pursuant to the provisions in Section 7.05) to each to account for any event requiring an adjustment to the Exchange Rate where the Ex-Dividend Date, the Effective Date or the date of the event occurs at any time during the period
when the Last Reported Sale Prices, the Daily VWAPs, the Daily Exchange Values, the Daily Settlement Amounts or any functions thereof are to be calculated. 

(j)         Successive Adjustments. After an adjustment to the Exchange Rate
under this Article 7, any subsequent event requiring an adjustment under this Article 7 will cause an adjustment to the Exchange Rate as so adjusted, without duplication. 

(k)         Limitations on Adjustments. 

(i)         Except as stated in this Article 7, the Issuer will not adjust the
Exchange Rate for the issuance of Ordinary Shares or any securities exchangeable into or exchangeable for Ordinary Shares or the right to purchase Ordinary Shares or such exchangeable or exchangeable securities. 

(ii)         In addition, notwithstanding anything to the contrary in this Section
7.05, the applicable Exchange Rate shall not be adjusted: 
 (A)         upon the
issuance of any Ordinary Shares pursuant to any present or future plan providing for the reinvestment of dividends or interest payable on the Guarantor’s securities and the investment of additional optional amounts in Ordinary Shares under any
plan; 
 (B)         upon the issuance of any Ordinary Shares or options or rights
to purchase Ordinary Shares pursuant to any present or future employee, director or consultant benefit plan or program of, or assumed by, the Guarantor or any of its Subsidiaries; 

(C)         upon the issuance of any Ordinary Shares pursuant to any option, warrant,
right or exercisable or exchangeable security not described in clause (B) above and outstanding as of the Issue Date; 

  
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 (D)         upon the repurchase of any
Ordinary Shares pursuant to an open-market share repurchase program including, pursuant to structured or derivative transactions such as accelerated share repurchase transactions or similar forward derivatives, or other buy-back transaction that is
not a tender offer or exchange offer of the nature described in Section 7.02(e); 
 (E)
        for a change solely in the nominal value of the Ordinary Shares; or 
 (F)
        for accrued and unpaid interest, if any. 
 (l)
        Notwithstanding anything to the contrary in this Section 7.05 the Issuer shall not be required to adjust the Exchange Rate unless such adjustment (together with any previous adjustments not then made)
would require an increase or decrease of at least 1% in the Exchange Rate; provided, however, that any such adjustments of less than one percent that are not required to be made will be carried forward and taken into account in any
subsequent adjustment, and provided, further, that any such adjustment of less than one percent that has not been made shall be made (i) in connection with any subsequent adjustment to the Exchange Rate of at least 1% (taking into
account all carried-forward adjustments that have not yet been made), (ii) on the Make-Whole Fundamental Change Effective Date for any Make-Whole Fundamental Change or upon the Redemption Notice Date in the case of any Tax Redemption or
Provisional Redemption, and (ii)(A) in the case of any Note to which Physical Settlement applies, upon the Exchange Date, and (B) in the case of any Note to which Cash Settlement or Combination Settlement applies, on each VWAP Trading Day of
the applicable Observation Period. Adjustments to the applicable Exchange Rate will be calculated to the nearest 1/10,000th of an Ordinary Share. 

(m)         For purposes of this Section 7.05, subject to Section 7.05(c) hereof, the
number of Ordinary Shares in issue at any time will include Ordinary Shares issuable in respect of scrip certificates issued in lieu of fractions of Ordinary Shares, but, so long as the Guarantor does not pay any dividend or make any distribution on
Ordinary Shares held in the treasury of the Guarantor, will not include Ordinary Shares held in the treasury of the Guarantor. 

(n)         Voluntary Adjustments. 

(i)         Incentive Increases. To the extent permitted by applicable law and
subject to the applicable rules of The NASDAQ Global Select Market (or any other securities exchange on which the Guarantor’s securities are then listed), the Issuer is permitted to increase the Exchange Rate by any amount for a period of at
least 20 Business Days if the Board of Directors determines that such increase would be in the Issuer’s best interest or the best interest of the Guarantor. 

(ii)         Tax-Related Increases. The Issuer may also (but is not required
to) increase the Exchange Rate to avoid or diminish income tax to holders of the Ordinary Shares or rights to purchase the Ordinary Shares in connection with a dividend or distribution of Ordinary Shares (or rights to acquire Ordinary Shares) or
similar event. 

  
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 (o)         Notices. 

(i)         Notice to Holders Prior to Certain Actions and Events. The Issuer
shall deliver notices of the events specified below at the times specified below and containing the information specified below unless, in each case, (i) pursuant to this Indenture, the Issuer is already required to deliver notice of such event
containing at least the information specified below at an earlier time, or, (ii) neither the Issuer nor the Guarantor, at the time notice is required to be delivered, has knowledge of all of the information required to be included in such
notice, in which case, the Issuer shall (A) deliver notice at such time containing only the information that it or the Guarantor has knowledge of at such time (if it or the Guarantor has knowledge of any such information at such time), and
(B) promptly upon it or the Guarantor obtaining knowledge of any such information not already included in a notice delivered by the Issuer, deliver notice to each Holder containing such information. In each case, the failure by the Issuer to
give such notice, or any defect therein, shall not affect the legality or validity of such event. 
 (ii)
        Issuances, Distributions, and Dividends and Distributions. If the Guarantor (A) announces any issuance of any rights, options or warrants that would require an adjustment in the Exchange
Rate pursuant to Section 7.05(b) hereof; (B) authorizes any distribution that would require an adjustment in the Exchange Rate pursuant to Section 7.05(c) hereof (including any separation of rights from the Ordinary Shares described in Section
7.05(h) hereof); or (C) announces any dividend or distribution that would require an adjustment in the Exchange Rate pursuant to Section 7.05(a) or Section 7.05(d) hereof, then the Issuer shall provide written notice to the Holders, Exchange
Agent (if other than the Trustee) and the Trustee reasonably promptly as possible following the applicable Ex-Dividend Date, which notice shall describe such issuance, distribution, dividend or distribution, as the case may be, and state the
Ex-Dividend Date and Record Date for such issuance, distribution, dividend or distribution, as the case may be. 
 (iii)
        Tender and Exchange Offers. If the Guarantor announces any tender offer or exchange offer that could require an adjustment in the Exchange Rate pursuant to Section 7.05(e) hereof, the Issuer
shall deliver notice thereof to the Holders on or promptly after the day the Guarantor publicly announces such tender offer or exchange offer. 

(iv)         Voluntary Increases. If the Issuer increases the Exchange Rate
pursuant to Section 7.05(n), the Issuer shall deliver notice to the Holders at least 15 calendar days prior to the date on which such increase will become effective, which notice shall state the date on which such increased will become effective and
the amount by which the Exchange Rate will be increased. 

  
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 (v)         Dissolutions,
Liquidations and Winding-Ups. If there is a voluntary or involuntary dissolution, liquidation or winding-up of the Issuer or the Guarantor, the Issuer shall deliver notice to the Holders as promptly as possible, but in any event at least 20
calendar days prior to the earlier of (i) the date on which such dissolution, liquidation or winding-up, as the case may be, is expected to become effective or occur, and (ii) the date or dates as of which it is expected that holders of
Ordinary Shares of record shall be entitled to exchange their Ordinary Shares for securities or other property deliverable upon such dissolution, liquidation or winding-up, as the case may be, which notice shall state the expected effective date and
record date for such event, as applicable, and the amount and kind of property that a holder of one Ordinary Share is expected to be entitled, or may elect, to receive in such event. The Issuer shall deliver an additional notice to Holders, as
promptly as practicable, whenever the expected effective date or record date, as applicable, or the amount and kind of property that a holder of one Ordinary Share is expected to be entitled to receive in such event, changes. 

(vi)         Notices After Certain Actions and Events. Whenever an adjustment
to the Exchange Rate becomes effective pursuant to this Section 7.05, the Issuer will (i) file with the Trustee an Officer’s Certificate stating that such adjustment has become effective, the Exchange Rate, and the manner in which the
adjustment was computed and (ii) deliver notice to the Holders stating that such adjustment has become effective and the Exchange Rate or exchange privilege as adjusted. Failure to give any such notice, or any defect therein, shall not affect
the validity of any such adjustment. 
 Section 7.06     Adjustments to Exchange Rate upon Exchange In
Connection With a Make-Whole Fundamental Change or a Tax Redemption. 
 (a)
        General. If (i) a Make-Whole Fundamental Change Effective Date occurs on or prior to the Maturity Date or (ii) the Issuer calls the Notes for redemption pursuant to a Tax Redemption
under Section 5.01(a) and a Holder elects to exchange its Notes “in connection with” such Make-Whole Fundamental Change or Tax Redemption, the Issuer will, in the circumstances described in this Section 7.06, increase the Exchange Rate
applicable to the Notes so surrendered for exchange by a number of additional Ordinary Shares (the “Additional Shares”) as set forth in this Section 7.06. For purposes of this Section 7.06, an exchange of Notes will be deemed for
these purposes to be “in connection with” (i) a Make-Whole Fundamental Change if the notice of the exchange of such Notes is received by the Exchange Agent during the period from, and including, the effective date of such Make-Whole
Fundamental Change (the “Make-Whole Fundamental Change Effective Date”) up to, and including, the Close of Business on the second Scheduled Trading Day immediately prior to the related Fundamental Change Repurchase Date (or, in the
case of a Make-Whole Fundamental Change that would have been a Fundamental Change but for the proviso in clause (2) of the definition of Fundamental Change, the 35th Business Day
immediately following the Make-Whole Fundamental Change Effective Date); or (ii) a Tax Redemption if the notice of exchange of such Notes is received by the Exchange Agent from, and including, the applicable Tax


  
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Redemption Notice Date up to, and including, the Close of Business on the second Scheduled Trading Day immediately prior to the related Redemption Date (any such period referred to in subclause
(i) or (ii), the “Make-Whole Fundamental Change Period”). 
 (b)
        Determination of Additional Shares. The number of Additional Shares, if any, by which the Exchange Rate will be increased will be determined by reference to the table below, based on the
Make-Whole Fundamental Change Effective Date or the Tax Redemption Notice Date, and the price (the “Ordinary Share Price”) paid (or deemed paid) per ordinary share in the Make-Whole Fundamental Change or on the Tax Redemption Notice
Date, as described below. If the holders of Ordinary Shares receive only cash in a Make-Whole Fundamental Change described in clause (2) of the definition of Fundamental Change, the Ordinary Share Price shall be the cash amount paid per
Ordinary Share. Otherwise, the Ordinary Share Price shall be the average of the Last Reported Sale Prices of the Ordinary Shares over the five Trading Day period ending on, and including, the Trading Day immediately preceding the Make-Whole
Fundamental Change Effective Date or the Tax Redemption Notice Date. In the event that an exchange in connection with a Tax Redemption would also be deemed to be in connection with a Make-Whole Fundamental Change, a Holder of the Notes to be
exchanged will be entitled to a single increase to the Exchange Rate with respect to the first to occur of the applicable date of the Tax Redemption Notice Date or the Make-Whole Fundamental Change Effective Date, and the later event will be deemed
not to have occurred for purposes of this Section 7.06. 
 (c)         Adjustment
of Ordinary Share Prices and Additional Shares. The Ordinary Share Prices set forth in the column headings of the table below will be adjusted as of any date on which the Exchange Rate of the Notes is otherwise required to be adjusted pursuant
to Section 7.05 hereof. The adjusted Ordinary Share Prices in the table below will equal the Ordinary Share Prices in effect immediately prior to such adjustment, multiplied by a fraction, the numerator of which is the Exchange Rate in effect
immediately prior to the adjustment giving rise to the adjustment to the Ordinary Share Price and the denominator of which is the Exchange Rate in effect immediately after such adjustment. The numbers of Additional Shares set forth in the table
below will be adjusted in the same manner and at the same time as the Exchange Rate must be adjusted as set forth in Section 7.05 hereof. 

(d)         Additional Shares Table. The following table sets forth the
hypothetical Ordinary Share price and the number of Additional Shares by which the Exchange Rate will be increased per $1,000 principal amount of Notes: 
  

																																																					
	 	 
	  	  	Ordinary Share Price  
	 
	Make-Whole Fundamental Change Effective Date / Tax Redemption Notice Date	  	 	$20.84	  	  	 	$23.00	  	  	 	$25.50	  	  	 	$28.66	  	  	 	$35.00	  	  	 	$42.50	  	  	 	$50.00	  	  	 	$60.00	  	  	 	$75.00	  	  	 	$90.00	  	  	 	$110.00	  	  	 	$130.00	  	  	 	$150.00	  
	 March 13, 2015
	  	 	13.0867	  	  	 	10.8811	  	  	 	8.9155	  	  	 	7.0606	  	  	 	4.6453	  	  	 	3.0174	  	  	 	2.0587	  	  	 	1.3042	  	  	 	0.7055	  	  	 	0.3972	  	  	 	0.1835	  	  	 	0.0766	  	  	 	0.0239	  
	 March 15, 2016
	  	 	13.0867	  	  	 	10.7381	  	  	 	8.6678	  	  	 	6.7323	  	  	 	4.2619	  	  	 	2.6502	  	  	 	1.7392	  	  	 	1.0537	  	  	 	0.5399	  	  	 	0.2895	  	  	 	0.1239	  	  	 	0.0453	  	  	 	0.0100	  
	 March 15, 2017
	  	 	13.0867	  	  	 	10.5178	  	  	 	8.3032	  	  	 	6.2565	  	  	 	3.7126	  	  	 	2.1397	  	  	 	1.3100	  	  	 	0.7344	  	  	 	0.3455	  	  	 	0.1732	  	  	 	0.0664	  	  	 	0.0188	  	  	 	0.0015	  
	 March 15, 2018
	  	 	13.0867	  	  	 	10.2228	  	  	 	7.7778	  	  	 	5.5411	  	  	 	2.8666	  	  	 	1.3777	  	  	 	0.7111	  	  	 	0.3374	  	  	 	0.1421	  	  	 	0.0687	  	  	 	0.0231	  	  	 	0.0036	  	  	 	0.0000	  
	 March 15, 2019
	  	 	13.0867	  	  	 	10.2032	  	  	 	7.4011	  	  	 	4.6889	  	  	 	0.9684	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  
	 March 15, 2020
	  	 	13.0867	  	  	 	10.3622	  	  	 	7.4545	  	  	 	4.6856	  	  	 	0.9607	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  
	 March 15, 2021
	  	 	13.0867	  	  	 	9.9160	  	  	 	6.9138	  	  	 	4.2051	  	  	 	0.8354	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  
	 March 15, 2022
	  	 	13.0867	  	  	 	8.5803	  	  	 	4.3178	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  


  
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 (e)         Use of Additional Shares
Table. The exact Ordinary Share Prices, Make-Whole Fundamental Change Effective Dates or Redemption Notice Dates may not be set forth in the table above, in which case: 

(i)         if the Ordinary Share Price is between two Ordinary Share Prices in the
table or the Make-Whole Fundamental Change Effective Date or Tax Redemption Notice Date is between two Make-Whole Fundamental Change Effective Dates or two Tax Redemption Notice Dates, as applicable, in the table, the number of Additional Shares
will be determined by a straight-line interpolation between the numbers of Additional Shares set forth in the table for the higher and lower Ordinary Share Prices and the earlier and later Make-Whole Fundamental Change Effective Dates or Tax
Redemption Notice Dates, as applicable, based on a 365-day year; 
 (ii)         if
the Ordinary Share Price is greater than $150.00 per Ordinary Share (subject to adjustment in the same manner as the Ordinary Share Prices set forth in the column headings of the table above) no Additional Shares will be added to the Exchange Rate;
and 
 (iii)         if the Ordinary Share Price is less than $20.84 per Ordinary
Share (subject to adjustment in the same manner as the Ordinary Share Prices set forth in the column headings of the table above) no Additional Shares will be added to the Exchange Rate. 

Notwithstanding the foregoing, in no event will the Exchange Rate, as increased pursuant to this Section 7.06 by the number of Additional
Shares, exceed 47.9846 Ordinary Shares per $1,000 principal amount of Notes, subject to adjustments in the same manner as the Exchange Rate is required to be adjusted as set forth in Section 7.05 hereof. 

(f)         Settlement of Exchanges “In Connection With” a Make-Whole
Fundamental Change or a Tax Redemption. If a Holder exchanges a Note “in connection with” a Make-Whole Fundamental Change or a Tax Redemption, the Issuer shall settle the exchange in accordance with Section 7.03 hereof (after giving
effect to any increase in the Exchange Rate required by this Section 7.06); provided, however, that if the consideration for the Ordinary Shares in any Make-Whole Fundamental Change described in clause (2) of the definition of
Fundamental Change is composed entirely of cash, for any exchange of Notes following the Make-Whole Fundamental Change Effective Date, the Exchange Obligation will be calculated based solely on the Ordinary Share Price for the transaction and will
be deemed to be an amount of cash per $1,000 principal amount of exchanged Notes equal to the applicable Exchange Rate (including any adjustment as described in this Section 7.06), multiplied by such Ordinary Share


  
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Price. In such event, the Exchange Obligation will be determined and paid to Holders in cash on the third Business Day following the Exchange Date. The Issuer shall notify Holders and the Trustee
in writing of the Make-Whole Fundamental Change Effective Date and issue a press release announcing such Make-Whole Fundamental Change Effective Date no later than five Business Days after such Make-Whole Fundamental Change Effective Date. 

Section 7.07     Effect of Recapitalization, Reclassification, Consolidation, Merger or Sale. 

(a)         In General. In the case of: 

(i)         any recapitalization, reclassification or change of the Ordinary Shares
(other than changes resulting from a subdivision or consolidation or change in nominal value); 

(ii)        any consolidation, merger, scheme of arrangement or offer or combination
involving the Guarantor; 
 (iii)        any sale, lease or other transfer to a
third party of the consolidated assets of the Guarantor and its Subsidiaries substantially as an entirety; or 

(iv)        any statutory share exchange; 

and, in each case, as a result of such event, the Ordinary Shares would be converted into, or exchanged for, stock, other securities, other
property or assets (including cash or any combination thereof) (each such event, a “Merger Event”), then at and after the effective time of such Merger Event, the right to exchange each $1,000 principal amount of Notes based on a
number of Ordinary Shares equal to the applicable Exchange Rate will be changed into a right to exchange such principal amount of Notes based on the kind and amount of shares of stock, other securities or other property or assets (including cash or
any combination thereof) that a holder of a number of Ordinary Shares equal to the Exchange Rate immediately prior to such transaction would have owned or been entitled to receive (without giving effect to any dissenters’ rights) (the
“Reference Property,” and the amount and kind of Reference Property that a holder of one Ordinary Share would have received in such transaction, a “Unit of Reference Property”) in such Merger Event; provided,
however, that at and after the effective time of the transaction, (i) the Issuer shall continue to have the right to determine the form of consideration to be paid or delivered, as the case may be, upon exchange of the Notes, as set
forth under Section 7.03, and (ii)(x) any amount payable in cash upon exchange of the notes as set forth under Section 7.03 will continue to be payable in cash, (y) any Ordinary Shares that the Issuer would have been required to cause to be
delivered upon exchange of the Notes as set forth under Section 7.03 will instead be deliverable in Units of Reference Property and (z) the Daily VWAP will be calculated based on the value of a Unit of Reference Property. 

If the transaction causes the Ordinary Shares to be exchanged into, or exchanged for, the right to receive more than a single
type of consideration (determined based in part 

  
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upon any form of shareholder election), the composition of a Unit of Reference Property will be deemed to be (i) the weighted average per Ordinary Share of the types and amounts of
consideration received by the holders of Ordinary Shares that affirmatively make such an election or (ii) if no shareholders affirmatively make such election, the types and amounts of consideration actually received by shareholders. If the
shareholders receive only cash in such transaction, then for all exchanges that occur after the effective date of such transaction (i) the Exchange Consideration of each $1,000 principal amount of Notes shall be solely cash in an amount equal
to the exchange rate in effect on the Exchange Date (as may be increased as described under Section 7.06), multiplied by the price paid per Ordinary Share in such transaction and (ii) the Issuer shall satisfy its Exchange Obligation by paying
cash to exchanging Holders on the third Business Day immediately following the Exchange Date. The Issuer will notify Holders, the Trustee and the Exchange Agent (if other than the Trustee) in writing of the weighted average as soon as practicable
after such determination is made. 
 (b)         In connection with such Merger
Event, the Issuer, the Guarantor or the successor or purchasing Person, as the case may be, shall execute with the Trustee a supplemental indenture permitted under Section 14.01(h) providing for such change in the right to convert each $1,000
principal amount of Notes. If, for any Merger Event, the Reference Property includes shares of stock, securities or other property or assets (including cash or any combination thereof) of a Person other than the successor or purchasing corporation,
as the case may be, in such Merger Event, then such supplemental indenture shall also be executed by such other Person and shall contain such additional provisions to protect the interests of the Holders or to implement the intent of the provisions
of Articles 7 or 8 as the Board of Directors shall reasonably consider necessary by reason of the foregoing. 
 (c)
        If the Issuer, the Guarantor or any successor or purchasing Person or other Person executes a supplemental indenture pursuant to Section 7.07(b) hereof, then the Issuer or such successor or purchasing
Person or other Person, as applicable, shall promptly file with the Trustee an Officer’s Certificate briefly stating the reasons therefore, the kind or amount of cash, securities or property or assets that will comprise a Unit of Reference
Property after the applicable Merger Event, any adjustment to be made with respect thereto and that all relevant conditions precedent have been complied with, and shall promptly deliver notice thereof to all Holders. If, at the time such a
supplemental indenture is executed, the Issuer cannot calculate the composition of a Unit of Reference Property because it is subject to a shareholder election, the Issuer may deliver notice of the kind or amount of cash, securities or property or
assets that will comprise a Unit of Reference Property after the Merger Event as promptly as practicable after it is able to make such calculation. Failure to deliver such notice shall not affect the legality or validity of such supplemental
indenture. 
 (d)         Neither the Issuer nor the Guarantor shall become a party
to any Merger Event unless its terms are consistent with the foregoing. None of the foregoing provisions shall affect the right of a Holder to exchange its Notes into cash, Ordinary Shares or a combination of cash and Ordinary Shares, as applicable,
as set forth in Sections 7.01, 7.02 and 7.03 prior to the effective date of such Merger Event. 

  
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 (e)         The above provisions of this
Section 7.07 shall similarly apply to successive Merger Events. 
 (f)         Upon
the consummation of any Merger Event, references to “Ordinary Shares” shall be deemed to refer to any Reference Property that constitutes share capital after giving effect to such Merger Event. 

Section 7.08     No Responsibility of Trustee. The Trustee and the Exchange Agent will not have any duty or
responsibility to any Holder to determine the Exchange Rate (or any adjustment thereto), whether any facts exist that require an adjustment of the Exchange Rate, or with respect to the nature or extent or calculation of any such adjustment when
made, or with respect to the method employed in making the same. Neither the Trustee nor the Exchange Agent will be responsible for any failure of the Issuer or the Guarantor, as applicable, to deliver any amount of cash and/or number of Ordinary
Shares, as applicable, upon the surrender of any Notes for the purpose of exchange or to comply with any of the duties, responsibilities or covenants of the Issuer contained in this Article 7. Without limiting the generality of the foregoing,
neither the Trustee nor the Exchange Agent will be under any responsibility to determine the correctness of any provisions contained in any supplemental indenture entered into pursuant to Section 7.07 hereof, including with respect to the
calculation of the amount of cash, the number of Units of Reference Property or the combination of cash and Units of Reference Property receivable by Holders upon the exchange of their Notes after any Merger Event, and each, subject to the
provisions of Article 11 in the case of the Trustee, may accept as conclusive evidence of the correctness of any such provisions, and will be protected in relying upon, the Officer’s Certificate (which the Issuer or the Guarantor, as
applicable, will be obligated to file with the Trustee prior to the execution of any such supplemental indenture) with respect thereto. 

ARTICLE 8 
 PURCHASE AT OPTION OF
HOLDERS UPON A FUNDAMENTAL CHANGE 
 Section 8.01     Fundamental Change Permits Holders to Require the Issuer
to Repurchase the Notes. 
 (a)         General. If a Fundamental Change
occurs at any time prior to the Maturity Date, then each Holder will have the right, at such Holder’s option, to require the Issuer to repurchase for cash, at the Fundamental Change Repurchase Price, (i) all of such Holder’s Notes or
(ii) any portion of such Holder’s Notes, which must be a principal amount such that the principal amount of the Notes not so repurchased equals $200,000 or an integral multiple of $1,000 in excess thereof. 

(b)         Fundamental Change Repurchase Price. The “Fundamental
Change Repurchase Price” means, for any Notes to be repurchased on a Fundamental Change Repurchase Date, a price equal to 100% of the principal amount of such Notes to be repurchased, plus accrued and unpaid interest to, but excluding, such
Fundamental Change Repurchase Date; provided, however, that if a Fundamental Change Repurchase Date occurs after a Regular Record Date, but on or prior to the Interest Payment Date corresponding to such Regular Record Date, the Issuer will
instead pay the full amount of accrued and unpaid interest to the Holder of record on such Regular Record Date and the 

  
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Fundamental Change Repurchase Price will be equal to 100% of the principal amount of the Notes to be repurchased. Any notes repurchased by the Issuer in connection with a Fundamental Change will
be paid for in cash. 
 (c)         Fundamental Change Repurchase Date. The
“Fundamental Change Repurchase Date” means, for any Fundamental Change, the date specified by the Issuer in the Fundamental Change Notice for such Fundamental Change, which date will be not less than 20 or more than 35 Business
Days, following the Fundamental Change Notice Date for such Fundamental Change. 
 Section 8.02     Fundamental
Change Notice. 
 (a)         General. On or before the 20th
calendar day after the occurrence of a Fundamental Change, the Issuer will deliver to each Holder, the Trustee and the Paying Agent (if other than the Trustee) a notice of the occurrence of such Fundamental Change and of the resulting repurchase
right (the “Fundamental Change Notice,” and the date of such delivery, the “Fundamental Change Notice Date”). 

For any Fundamental Change, the Fundamental Change Notice shall state: 

(i)          the events causing such Fundamental Change and whether such
transaction is also a Make-Whole Fundamental Change; 
 (ii)         the date of
such Fundamental Change; 
 (iii)        the last date on which a Holder may exercise
its right to require the Issuer to repurchase its Notes as a result of such Fundamental Change under this Article 8; 

(iv)        the Fundamental Change Repurchase Price for each $1,000 principal amount of
Notes for such Fundamental Change; 
 (v)         the Fundamental Change Repurchase
Date for such Fundamental Change; 
 (vi)        the name and address of the Paying
Agent and the Exchange Agent, if applicable; 
 (vii)       if applicable, the applicable
Exchange Rate and any adjustments to the applicable Exchange Rate; 
 (viii)      if applicable,
that the Notes with respect to which a Fundamental Change Repurchase Notice has been delivered by a Holder may be exchanged only if such Holder withdraws such Fundamental Change Repurchase Notice in accordance with the terms of this Indenture or to
the extent that a portion of such Notes is not subject to such Fundamental Change Repurchase Notice; and 

  
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 (ix)         the procedures that a
Holder must follow to require the Issuer to repurchase a Note. 
 Simultaneously with delivering any Fundamental Change
Notice, the Issuer will publish a notice containing this information on the Guarantor’s website or through such other public medium as we may use at that time. 

(b)         Failure or Defect. Notwithstanding anything to the contrary
contained elsewhere in this Indenture, neither the failure of the Issuer to deliver a Fundamental Change Notice nor a defect in a Fundamental Change Notice delivered by the Issuer will limit the repurchase rights of any Holder under this Article 8
or impair or otherwise affect the validity of any proceedings relating to the repurchase of any Note pursuant to this Article 8. 

Section 8.03     Fundamental Change Repurchase Notice. 

(a)         General. To exercise its repurchase rights under Section 8.01(a)
hereof with respect to any Fundamental Change, a Holder must deliver to the Paying Agent, on or before the second Scheduled Trading Day immediately preceding the Fundamental Change Repurchase Date: 

(i)         a duly completed “Form of Fundamental Change Repurchase Notice”
in the form of Attachment 2 of the Notes that such Holder is tendering for repurchase (a “Fundamental Change Repurchase Notice”); and 

(ii)         the Notes that such Holder is tendering for repurchase, (A) by
book-entry transfer if such Notes are Global Notes, or (B) by physical delivery, if such Notes are Physical Notes, in each case, together with any endorsements or other documents reasonably requested by the Paying Agent. 

(b)         Contents of Fundamental Change Repurchase Notice. The Fundamental
Change Repurchase Notice for any Note must state: 
 (i)         if such Note is to
be repurchased in part, the portion of the principal amount of such Note to be repurchased, which must be a principal amount such that the principal amount of the Notes not so repurchased equals $200,000 or an integral multiple of $1,000 in excess
thereof; 
 (ii)         that such Note will be repurchased by the Issuer pursuant
to the applicable provisions of this Article 8; and 
 (iii)         if such Note
to be repurchased is a Physical Note, the certificate number of such Note. 
 If the Notes to be repurchased are Global Notes, the
Fundamental Change Notice for such Notes must comply with the Applicable Procedures. 

  
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 (c)         Notices to Issuer. If
any Holder validly delivers to the Paying Agent a Fundamental Change Repurchase Notice with respect to any Note or any portion of a Note, the Paying Agent (if other than the Issuer) will promptly deliver to the Issuer a copy of such Fundamental
Change Repurchase Notice. 
 (d)         Effect of Improper Notice. Unless
and until the Paying Agent receives a validly endorsed and delivered Fundamental Change Repurchase Notice with respect to a Note, together with such Note, in a form that conforms with the description contained in such Fundamental Change Repurchase
Notice, the Holder submitting the Notes will not be entitled to receive the Fundamental Change Repurchase Price for such Note. 

Section 8.04     Withdrawal of Fundamental Change Repurchase Notice. 

(a)         General. If a Holder delivers a Fundamental Change Repurchase
Notice with respect to any Note, such Holder may withdraw such Fundamental Change Repurchase Notice (in whole or in part) by delivering to the Paying Agent a written notice of withdrawal prior to the Close of Business on the second Scheduled Trading
Day immediately preceding the Fundamental Change Repurchase Date. Any such withdrawal notice must state: 
 (i)
        the principal amount of the Notes to be withdrawn, which must be such that the principal amount not to be repurchased equals $200,000 or an integral multiple of $1,000 in excess thereof; 

(ii)         the principal amount of the Notes, if any, that remains subject to the
original Fundamental Change Repurchase Notice; and 
 (iii)         if the Notes
with respect to which such Fundamental Change Repurchase Notice pertained were Physical Notes, the certificate numbers of the Notes to be withdrawn and the Notes that will remain subject to the Fundamental Change Repurchase Notice, if any. 

If the Notes to be withdrawn are Global Notes, a Holder must deliver its notice of withdrawal in compliance with the Applicable Procedures.

 (b)         Return of Note. Upon receipt of a validly delivered withdrawal
notice, the Paying Agent will promptly (i) if such notice pertains to a Physical Note or a portion of a Physical Note, return such Note or portion of a Note to such Holder, in the amount specified in such withdrawal notice; and, (ii) if
such notice pertains to a beneficial interest in a Global Note, in compliance with the Applicable Procedures, deem to be cancelled any instructions for book-entry transfer of such beneficial interest, in the amount specified in such withdrawal
notice. 
 (c)         Notice to Issuer. If any Holder validly delivers to
the Paying Agent a notice of withdrawal with respect to a Note or any portion of a Note, the Paying Agent (if other than the Issuer) will promptly deliver to the Issuer a copy of such notice of withdrawal. 

  
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 Section 8.05     Effect of Fundamental Change Repurchase Notice.

 (a)         General. If a Holder validly delivers to the Paying Agent a
Fundamental Change Repurchase Notice with respect to any Note or any portion of any Note, such Holder may no longer exchange such Note or portion of a Note, as the case may be, unless and until such Holder validly withdraws such Fundamental Change
Repurchase Notice. 
 (b)         Timing of Payment. Upon the Paying
Agent’s receipt of (i) a valid Fundamental Change Repurchase Notice and (ii) the Notes to which such Fundamental Change Repurchase Notice pertains, the Holder of the Notes to which such Fundamental Change Repurchase Notice, as
applicable, pertains will be entitled, except to the extent such Holder has validly withdrawn such Fundamental Change Repurchase Notice, to receive the Fundamental Change Repurchase Price with respect to such Notes on the later of (i) the
Fundamental Change Repurchase Date and (ii)(A) if such Notes are Physical Notes, the date of delivery of such Notes to the Paying Agent, or (B) if such Notes are Global Notes, the date of book-entry transfer of such Notes to the Paying Agent,
or, if such later date is not a Business Day, the Business Day immediately following such later date. 
 (c)
        Effect of Deposit. If, by 11:00 a.m., New York City time, on the Fundamental Change Repurchase Date for any Fundamental Change, the Paying Agent holds money sufficient to pay the Fundamental
Change Repurchase Price for every Note subject to a Fundamental Change Repurchase Notice, validly delivered in accordance with Section 8.03 hereof and not validly withdrawn in accordance with Section 8.04 hereof, then, at the Close of Business on
the Fundamental Change Repurchase Date: 
 (i)         the Notes to be repurchased
will cease to be outstanding and interest will cease to accrue on such Notes (whether or not book-entry transfer of such Notes is made or whether or not such Notes are delivered to the Paying Agent); and 

(ii)         all other rights of the Holders with respect to such Notes will
terminate (other than the right to receive the Fundamental Change Repurchase Price, as applicable, and previously accrued and unpaid interest, upon delivery or transfer of the Notes). 

Section 8.06     Notes Repurchased in Whole or in Part. If any Physical Note is to be repurchased only in
part, the Holder must surrender such Note at the office of the Paying Agent (with, if the Issuer or the Trustee so requires, due endorsement by, or a written instrument of transfer in form satisfactory to the Issuer and the Trustee duly executed by,
the Holder of such Note or such Holder’s attorney-in-fact duly authorized in writing), whereupon the Issuer will execute, in accordance with Section 3.03, and the Trustee will authenticate, in accordance with Section 3.03, and deliver to the
surrendering Holder, without a service charge, a new Note or Notes of any authorized denomination or denominations requested by such Holder in aggregate principal amount equal to the portion of the principal amount of the Note so surrendered which
is not repurchased. If any Global Note is repurchased in part, the Issuer will instruct the Registrar, 

  
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in accordance with the Applicable Procedures, to decrease the principal amount of such Global Note by the principal amount repurchased. Any Notes that are repurchased or owned by the Issuer,
whether or not in connection with a Fundamental Change will be submitted to the Trustee for cancellation and will be duly retired by the Issuer. 

Section 8.07     Covenant to Comply with Securities Laws upon Repurchase of Notes. In connection with any
repurchase offer pursuant to a Fundamental Change Repurchase Notice under this Article 8, the Issuer will, if required, (i) comply with Rule 13e-4 and any other tender offer rules under the Exchange Act that may be applicable at the time of the
offer to repurchase the Notes, (ii) file the related Schedule TO (or any successor schedule, form or report) or any other required schedule under the Exchange Act, and (iii) otherwise comply with any applicable United States federal and
state securities laws applicable to it in connection with such repurchase offer. 
 Section 8.08     Deposit
Fundamental Change Repurchase Price. By 11:00 a.m., New York City time, on the Fundamental Change Repurchase Date, the Issuer will deposit with the Trustee or with the Paying Agent (or, if the Issuer or a Subsidiary or an Affiliate of either of
them is acting as the Paying Agent, will segregate and hold in trust as provided in Section 11.06) an amount of immediately available funds sufficient to pay the Fundamental Change Repurchase Price of all the Notes or portions thereof that the
Issuer is required to repurchase on such Fundamental Change Repurchase Date. 
 Section 8.09     Covenant Not to
Repurchase Notes upon Certain Events of Default. 
 (a)         General.
Notwithstanding anything to the contrary in this Article 8, no Notes may be repurchased at the option of Holders upon a Fundamental Change if the principal amount of the Notes has been accelerated, and such acceleration has not been rescinded, on or
prior to such date (except in the case of an acceleration resulting from a default by the Issuer that would be cured by the Issuer’s payment of the Fundamental Change Repurchase Price, as applicable, with respect to such Notes). 

(b)         Deemed Withdrawals. If, on any Fundamental Change Repurchase Date,
(i) a Fundamental Change Repurchase Notice for a Note has been validly tendered in accordance with Section 8.03 hereof and has not been validly withdrawn in accordance with Section 8.03 hereof, and (ii) pursuant to this Section 8.09, the
Issuer is not permitted to purchase Notes, the Paying Agent will deem such Fundamental Change Repurchase Notice withdrawn. 

(c)         Return of Notes. If a Holder tenders a Note for purchase pursuant
to this Article 8 and, on the Fundamental Change Repurchase Date, pursuant to this Section 8.09, the Issuer is not permitted to purchase such Note, the Paying Agent will (i) if such Note is a Physical Note, return such Note to such Holder, and
(ii) if such Note is held in book-entry form, in compliance with the Applicable Procedures, deem to be cancelled any instructions for book-entry transfer of such Note. 

  
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 ARTICLE 9 

EVENTS OF DEFAULT; REMEDIES 

Section 9.01     Events of Default. 

(a)         General. Each of the following is an “Event of
Default” with respect to the Notes: 
 (i)         the Issuer shall fail
to pay or cause to be paid an installment of interest, if any, on any of the Notes, which failure continues for 30 days after the date when due; 

(ii)         the Issuer shall fail to pay or cause to be paid the principal of any
Note (including the Fundamental Change Repurchase Price and Redemption Price, if applicable) when the same becomes due and payable at its stated maturity, upon redemption, upon required repurchase, upon declaration of acceleration or otherwise; 

(iii)         the Issuer or the Guarantor, as applicable, shall fail to pay or
deliver when due any part of the Exchange Obligation with respect to any Note in accordance with Article 7 hereof and such failure continues for three Business Days; 

(iv)         the Issuer shall fail to comply with its notice obligations under
Article 8, Section 7.01(c) or Section 7.06 of this Indenture; 
 (v)         the
Issuer or the Guarantor shall fail to comply with its respective obligations under Article 10 of this Indenture; 
 (vi)
        the Issuer shall fail to perform or observe (or obtain a waiver with respect to) any term, covenant or agreement contained in the Notes or this Indenture and not otherwise explicitly provided for in
this Section 9.01(a) for a period of 60 days after receipt by the Issuer of notice of such failure from the Trustee or by the Issuer and the Trustee from the Holders of at least 25% of the aggregate principal amount of then outstanding Notes; 

(vii)         the Issuer, the Guarantor or any of the Guarantor’s Significant
Subsidiaries shall be in default with respect to any mortgage, agreement or other instrument under which there may be outstanding, or by which there may be secured or evidenced, any indebtedness for money borrowed in excess of $25.0 million (or its
foreign currency equivalent at the time) in the aggregate of the Issuer, the Guarantor and/or any of its Significant Subsidiaries at any one time outstanding, whether such indebtedness exists as of the date hereof or shall thereafter be created
(x) resulting in such indebtedness becoming or being declared due and payable or (y) constituting a failure to pay the principal or interest of any such indebtedness when due and payable at its stated maturity, upon redemption, upon
required repurchase, upon declaration of acceleration or otherwise, and such acceleration shall not have been rescinded or annulled or such 

  
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failure to pay shall have been cured within 60 calendar days after written notice has been received by the Issuer, the Guarantor or such Significant Subsidiary from the Trustee or Holders of at
least 25% in aggregate principal amount of the outstanding Notes; 
 (viii)
        a final judgment or judgments for the payment of $40.0 million (or its foreign currency equivalent at the time) or more (excluding any amounts covered by insurance or bond) in the aggregate rendered
against the Issuer, the Guarantor or any of the Guarantor’s Significant Subsidiaries by a court of competent jurisdiction, which judgment is not discharged, stayed, vacated, paid or otherwise satisfied within 60 days after (i) the date on
which the right to appeal thereof has expired if no such appeal has commenced, or (ii) the date on which all rights to appeal have been extinguished; 

(ix)         the Issuer, the Guarantor or any of the Guarantor’s Subsidiaries
that are Significant Subsidiaries, pursuant to or within the meaning of the Bankruptcy Law: 
 (A)
        commences as a debtor a voluntary case or proceeding to be adjudicated bankrupt or insolvent; 

(B)         consents to the entry of an order for relief against it in an involuntary
case or proceeding or the commencement of any case against it; 
 (C)
        consents to the appointment of a receiver or examiner of it or for all or substantially all of its property; 

(D)         makes a general assignment for the benefit of its creditors; 

(E)         files a petition in bankruptcy or answer or consent seeking
reorganization or relief; 
 (F)         consents to the filing of such a petition
or the appointment of an examiner or the appointment or taking possession by a receiver; or 
 (G)
        a court of competent jurisdiction enters an order or decree under any Bankruptcy Law that: 

(1)         grants relief against the Issuer, the Guarantor or any of their
respective subsidiaries in an involuntary case or proceeding or adjudicates the Issuer, the Guarantor or any of their respective Subsidiaries insolvent or bankrupt; 

(2)         appoints a receiver or an examiner of the Issuer, the Guarantor or any of
their respective Subsidiaries for all or substantially all of the property of the Issuer, the Guarantor or any of their respective Subsidiaries; or 

  
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 (3)         orders the winding up or
liquidation of the Issuer, the Guarantor or any of their respective Subsidiaries; 
 and, in each case, the order or decree remains
unstayed and in effect for 90 consecutive days; or 
 (x)         The Guarantee
ceases to be in full force and effect (except as contemplated by the terms of this Indenture) or is declared null and void in a judicial proceeding or the Guarantor denies or disaffirms its obligations under this Indenture or the Guarantee. 

Section 9.02     Acceleration. 

(a)         Acceleration. If any other Event of Default occurs and is
continuing (other than an Event of Default specified in Section 9.01(a)(ix) hereof with respect to the Issuer or the Guarantor), the Trustee by notice to the Issuer, or the Holders of at least 25% in aggregate principal amount of then outstanding
Notes by written notice to the Issuer and the Trustee, may, and the Trustee at the written request of such Holders shall, declare 100% of the principal amount of and accrued and unpaid interest on all the outstanding Notes to be due and payable. If
an Event of Default specified in Sections 9.01(a)(ix) hereof occurs with respect to the Issuer or the Guarantor, the principal amount of and accrued and unpaid interest on all of the then outstanding Notes will immediately become due and payable
without any further action or notice by any party. Upon such a declaration of acceleration, such principal and accrued and unpaid interest, if any, will be due and payable immediately. 

(b)         Rescission of Events of Default and/or Acceleration.
Notwithstanding anything to the contrary in this Indenture, the Holders of a majority in principal amount of then outstanding Notes may waive all past Defaults and Events of Default (except with respect to nonpayment of principal (including the
Fundamental Change Repurchase Price and Redemption Price) or interest or with respect to the Issuer’s failure to deliver the Exchange Obligation as required under Article 7 hereof) and rescind and annul any such acceleration with respect to the
Notes and its consequences hereunder by delivering notice to the Trustee if (i) rescission would not conflict with any judgment or decree of a court of competent jurisdiction and (ii) all existing Events of Default, other than the
nonpayment of the principal of (including the Fundamental Change Repurchase Price and Redemption Price, if applicable) and interest on the Notes that have become due solely by such declaration of acceleration, have been cured or waived. 

Section 9.03     Other Remedies. If an Event of Default occurs and is continuing, the Trustee may pursue any
available remedy to collect the payment of the principal of, accrued and unpaid interest on, the Redemption Price for or the Fundamental Change Repurchase Price for, the Notes, the payment and/or delivery of the Exchange Obligation, the payment of
Additional Amounts, if any, or to enforce the performance of any provision of the Notes or this Indenture. 
 The Trustee may maintain a
proceeding even if it does not possess any of the Notes or produce any of the Notes in the proceeding. A delay or omission by the Trustee or any Holder in 

  
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exercising any right or remedy accruing upon an Event of Default will not impair the right or remedy or constitute a waiver of or acquiescence in the Event of Default. No remedy is exclusive of
any other remedy. All available remedies are cumulative, except as otherwise provided in this Indenture. 
 Section 9.04
    Sole Remedy for Failure to Report. 
 (a)
        General. Notwithstanding anything to the contrary in the Notes or in this Indenture, to the extent the Issuer elects, the sole remedy for an Event of Default relating to the Issuer’s or the
Guarantor’s failure to comply with its reporting obligations as set forth under Section 4.07 (any such Event of Default, a “Reporting Default”), will, for the first 270 days after the occurrence of such Reporting Default,
consist exclusively of the right to receive Additional Interest at a rate equal to (x) 0.25% per annum of the principal amount of then outstanding Notes for each day during the first 90 days after the occurrence of such Reporting Default
during which such Reporting Default is continuing and (y) 0.50% per annum on the principal amount of then outstanding Notes from the 91st day until the 270th day following the occurrence of such Reporting Default during which Reporting
Default is continuing. 
 (b)         Issuer Election. In order to elect to
pay the Additional Interest as the sole remedy during the first 270 days after the occurrence of a Reporting Default in accordance with Section 9.04(a) hereof, the Issuer must notify all Holders, the Trustee and the Paying Agent (if other than the
Trustee) in writing of such election prior to the beginning of such 270-day period. Any Additional Interest payable pursuant to this Section 9.04 will be payable in arrears on each Interest Payment Date following accrual in the same manner as
ordinary interest is payable and will be separate and distinct from, and in addition to, any Additional Interest that may accrue pursuant to Section 4.06. 

(c)         Limitation on Remedy. 

(i)         On the 271st day after the occurrence of such Reporting Default (if such
Reporting Default is not cured or waived prior to such 271st day), the Notes will immediately be subject to acceleration in accordance with Section 9.02 hereof. 

(ii)         In addition, if a Reporting Default occurs and the Issuer fails to
timely elect to pay Additional Interest pursuant to Section 9.04(b) hereof (or the Issuer elects to pays such Additional Interest but does not pay the Additional Interest when due), the Notes will immediately be subject to acceleration pursuant to
Section 9.02 hereof on account of such Reporting Default. 
 (iii)
        Notwithstanding anything to the contrary herein, if the Issuer elects to pay the Additional Interest with respect to any Reporting Default, the Issuer’s election will not affect the rights of any
Holder with respect to any other Event of Default. 
 (iv)         In no event
shall Additional Interest payable pursuant to this Section 9.04 accrue, together with any Additional Interest payable pursuant to 

  
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Section 4.06, at a rate per year in excess of 0.50% per annum, regardless of the number of events or circumstances giving rise to requirements to pay such Additional Interest pursuant to
this Section 9.04 or Section 4.06. 
 Section 9.05     [Reserved]. 

Section 9.06     Control By Majority. At any time, the Holders of a majority of the aggregate principal amount
of the then outstanding Notes may direct the time, method and place of conducting any proceeding for any remedy available to the Trustee or for exercising any trust or power conferred on the Trustee. However, the Trustee may refuse to follow any
direction that conflicts with law or this Indenture or, subject to the Trustee’s duties under Article 11 and the Trust Indenture Act, that the Trustee determines to be unduly prejudicial to the rights of any other Holder, or that would
potentially involve the Trustee in personal liability. Prior to taking any action hereunder, the Trustee will be entitled to indemnification satisfactory to it against any loss, liability or expense caused by taking or not taking such action. 

Section 9.07     Limitation on Suits. Subject to Article 10 hereof, if an Event of Default occurs and is
continuing, the Trustee will be under no obligation to exercise any of the rights or powers under this Indenture at the request or direction of any of the Holders unless such Holders have offered to the Trustee indemnity or security satisfactory to
it against any loss, liability or expense. Except to enforce the right to receive payment of principal (including the payment of the Fundamental Change Repurchase Price and Redemption Price, if applicable), Additional Amounts or interest when due,
or the right to receive payment or delivery of the Exchange Consideration, no Holder may pursue any remedy with respect to the Indenture or the Notes unless: 

(a)         such Holder has previously given the Trustee written notice that an Event
of Default has occurred and is continuing; 
 (b)         Holders of at least 25% of
the aggregate principal amount of the then outstanding Notes deliver to the Trustee a written request that the Trustee pursue a remedy with respect to such Event of Default; 

(c)         such Holder or Holders have offered and, if requested, provided to the
Trustee security or indemnity satisfactory to the Trustee against any loss, liability or other expense of compliance with such written request; 

(d)         the Trustee has not complied with such written request within 60 days
after receipt of such written request and offer of security or indemnity; and 
 (e)
        during such 60-day period, the Holders of a majority of the aggregate principal amount of the then outstanding Notes did not deliver to the Trustee a direction inconsistent with such written request.

 A Holder may not use this Indenture to prejudice the rights of any other Holder or to obtain a preference or priority over any other
Holder, it being understood that the Trustee does not have any affirmative duty to ascertain whether any usage of this Indenture by a Holder is unduly prejudicial to such other Holders. 

  
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 Section 9.08     Rights of Holders to Receive Payment and to
Exchange. Notwithstanding anything to the contrary elsewhere in this Indenture, the right of any Holder to receive payment of the principal of, Redemption Price for, Fundamental Change Repurchase Price for, Additional Amounts with respect to,
and accrued and unpaid interest on, its Notes, on or after the respective due date, and to exchange its Notes and receive the Exchange Obligation due with respect to such Notes in accordance with Article 7 hereof, or to bring suit for the
enforcement of any such payment or exchange rights, will not be impaired or affected without the consent of such Holder and will not be subject to the requirements of Section 9.07 hereof. 

Section 9.09     Collection Suit by Trustee. If an Event of Default specified in Section 9.01(a)(i),
9.01(a)(ii)or 9.01(a)(iii) hereof occurs and is continuing or an acceleration pursuant to Section 9.02 occurs and has not been waived or rescinded, the Trustee is authorized to recover judgment in its own name and as trustee of an express trust
against the Issuer for the whole amount of principal of, interest on, Fundamental Change Repurchase Price for, Redemption Price for, Additional Amounts with respect to, and Exchange Obligation with respect to, the Notes, as the case may be, and to
the extent lawful, any default interest on such principal, interest, Fundamental Change Repurchase Price, Redemption Price and Additional Amounts, and such further amount as is sufficient to cover the costs and expenses of collection, including the
reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, as well as any other amounts that may be due under Section 11.07. 

Section 9.10     Trustee May Enforce Claims Without Possession of Notes. All rights of action and claims under
this Indenture or the Notes may be prosecuted and enforced by the Trustee without the possession of any of the Notes or the production thereof in any proceeding relating thereto, and any such proceeding instituted by the Trustee shall be brought in
its own name as trustee of an express trust, and any recovery of judgment shall, after provision for the payment of the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, be for the ratable benefit
of the Holders in respect of which such judgment has been recovered. 
 Section 9.11     Trustee May File Proofs
of Claim. The Trustee is authorized to file such proofs of claim and other papers or documents as may be necessary or advisable to have the claims of the Trustee and the Holders allowed in any judicial proceedings relative to the Issuer or the
Guarantor, their respective creditors or its property and, unless prohibited by law or applicable regulations, will be entitled to collect, receive and distribute any money or other property payable or deliverable on any such claims, and any
Custodian in any such judicial proceeding is hereby authorized by each Holder to make such payments to the Trustee, and, in the event that the Trustee consents to the making of such payments directly to the Holders, to pay to the Trustee any amount
due to it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the Trustee under Section 11.07. To the extent that the payment of any such compensation, expenses,
disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the Trustee under Section 11.07 out of the estate in any such proceeding, will be denied for any reason, payment of the same will be secured by a lien on,
and is paid out of, any and all distributions, dividends, money, securities and other properties that the Holders may be entitled to receive in such proceeding, whether in liquidation or under any plan of reorganization or arrangement or otherwise.
Nothing herein contained will be deemed to authorize the Trustee to 

  
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authorize or consent to, or to accept or to adopt on behalf of any Holder, any plan of reorganization, arrangement, adjustment or composition affecting the Notes or the rights of any Holder, or
to authorize the Trustee to vote in respect of the claim of any Holder in any such proceeding. 
 Section 9.12
    Restoration of Rights and Remedies. If the Trustee or any Holder has instituted any proceeding to enforce any right or remedy under this Indenture and such proceeding has been discontinued or abandoned for any reason,
or has been determined adversely to the Trustee or to such Holder, then and in every such case, subject to any determination in such proceeding, the Issuer, the Trustee and the Holders shall be restored severally and respectively to their former
positions hereunder and thereafter all rights and remedies of the Trustee and the Holders shall continue as though no such proceeding had been instituted. 

Section 9.13     Rights and Remedies Cumulative. Except as otherwise provided with respect to the replacement
or payment of mutilated, destroyed, lost or stolen Notes in Section 3.08, no right or remedy herein conferred upon or reserved to the Trustee or to the Holders is intended to be exclusive of any other right or remedy, and every right and remedy
shall, to the extent permitted by law, be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder, or
otherwise, shall not prevent the concurrent assertion or employment of any other appropriate right or remedy. 
 Section 9.14
    Delay or Omission Not a Waiver. No delay or omission of the Trustee or of any Holder to exercise any right or remedy accruing upon any Event of Default shall impair any such right or remedy or constitute a waiver of
any such Event of Default or an acquiescence therein. Every right and remedy given by this Article 9 or by law to the Trustee or to the Holders may be exercised from time to time and as often as may be deemed expedient by the Trustee (subject to the
limitations contained in this Indenture) or by the Holders, as the case may be. 
 Section 9.15
    Priorities. If the Trustee collects any money pursuant to this Article 9, it will pay out the money in the following order: 

FIRST: to the Trustee, in each of its capacities hereunder, its agents and attorneys for amounts due under this Indenture, including payment
of all compensation, expenses and liabilities incurred, and all advances made, by the Trustee and the costs and expenses of collection; 

SECOND: to the Holders, for any amounts due and unpaid on the principal of, Redemption Price for, Fundamental Change Repurchase Price for,
Additional Amounts with respect to, accrued and unpaid interest on, and cash portion of the Exchange Obligation with respect to, any Note, without preference or priority of any kind, according to such amounts due and payable on all of the Notes; and

 THIRD: the balance, if any, to the Issuer or to such other party as a court of competent jurisdiction directs. 

  
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 The Trustee may fix a record date and payment date for any payment to the Holders pursuant to
this Section 9.15. If the Trustee so fixes a record date and a payment date, at least 15 days prior to such record date, the Issuer will deliver to each Holder and the Trustee a written notice, which notice will state such record date, such payment
date and the amount of such payment. 
 Section 9.16     Undertaking for Costs. All parties to this
Indenture agree, and each Holder of a Note, by such Holder’s acceptance thereof, shall be deemed to have agreed, that any court may in its discretion require, in any suit for the enforcement of any right or remedy under this Indenture, or in
any suit against the Trustee for any action taken or omitted by it as Trustee, the filing by any party litigant in such suit of an undertaking to pay the costs of such suit, and that such court may in its discretion assess reasonable costs,
including reasonable attorneys’ fees and expenses, against any party litigant in such suit, having due regard to the merits and good faith of the claims or defenses made by such party litigant; provided, however, that the provisions of this
Section 9.16 shall not apply to any suit instituted by the Trustee, to any suit instituted by any Holder, or group of Holders, holding in the aggregate more than 10% in aggregate principal amount of the Notes then outstanding, or to any suit
instituted by any Holder for the enforcement of the payment of the principal of, the Redemption Price, Fundamental Change Repurchase Price with respect to, Additional Amounts with respect to, or accrued and unpaid interest on, any Note on or after
the due date expressed or provided for in such Note or to any suit for the enforcement of the right to exchange any Note in accordance with the provisions of Article 7 hereof. 

ARTICLE 10 
 CONSOLIDATION, MERGER,
AMALGAMATION OR SALE OF ASSETS AND TAX RESIDENCE 
 Section 10.01     Issuer and Guarantor May Consolidate on
Certain Terms. Neither the Issuer nor the Guarantor shall consolidate with or merge or amalgamate into any Person or enter into a scheme of arrangement (unless the Issuer or the Guarantor, as applicable, is the surviving person) or sell, lease
or otherwise transfer their respective consolidated properties and assets, substantially as an entirety, to another Person (other than for the Guarantor to sell, lease or otherwise transfer such assets or properties to one or more of its direct or
indirect Wholly Owned Subsidiaries), unless: 
 (a)         the Person (if other
than the Issuer or the Guarantor, as applicable) formed by such consolidation or into which the Issuer or the Guarantor, as applicable, is merged, amalgamated or of which the Issuer or the Guarantor becomes a subsidiary pursuant to a scheme of
arrangement or the Person which acquires by sale, lease or other transfer of the consolidated properties and assets of the Issuer or the Guarantor, substantially as an entirety, shall (x) be a corporation, limited liability company,
partnership, trust or other business entity organized and existing under the laws of the United States of America, any state thereof, the District of Columbia, the Republic of Ireland (meaning Ireland exclusive of Northern Ireland) or Bermuda;
provided, however that in the case of the Guarantor, such person is treated as a corporation for U.S. federal income tax purposes and (y) such Person (if other than the Issuer or the Guarantor, as applicable) expressly assumes, by
an indenture supplemental hereto, executed and delivered to the Trustee, in 

  
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form satisfactory to the Trustee, the obligations of the Issuer or the Guarantor, as the case may be, under the Notes and this Indenture (including, for the avoidance of doubt, the obligations
under Section 4.10); and 
 (b)         after giving effect to such transaction, no
Default or Event of Default shall have occurred and be continuing. 
 Section 10.02 Successor to Be Substituted. Upon any such
consolidation, merger, amalgamation or transfer, the resulting, surviving, transferee or successor Person (if not the Issuer or the Guarantor, as the case may be) shall succeed to, and may exercise every right and power of the Issuer or the
Guarantor’s under, this Indenture, and the Issuer or the Guarantor, as the case may be, shall be discharged from the obligations under the Notes and this Indenture except in the case of any such lease. 

In case of any such consolidation, merger, amalgamation, sale, lease or other transfer, such changes in phraseology and form (but not in
substance) may be made in the Notes thereafter to be issued as may be appropriate. 
 Section 10.03 Change of Tax Residence.
None of the Issuer, the Guarantor or any successor thereof shall be a tax resident of a tax jurisdiction other than the United States, the Republic of Ireland (meaning Ireland exclusive of Northern Ireland) or Bermuda unless being a tax resident of
such jurisdiction will not provide the Issuer a right to redeem the Notes under Section 5.01 either under the laws in force at that time such Person became a tax resident or successor thereto or laws announced at that time; provided that, the Issuer
will continue to have the benefit of Section 5.01 after such change of jurisdiction in compliance with the above provisions. The Issuer has filed an election to be classified for U.S. federal tax purposes as a disregarded entity, and will remain so
for so long as any of the Notes are outstanding. 
 ARTICLE 11 

THE TRUSTEE 
 Section 11.01
  Duties and Responsibilities of Trustee. 
 (a)        The
Trustee, prior to the occurrence of an Event of Default and after the curing of all Events of Default which may have occurred, undertakes to perform such duties and only such duties as are specifically set forth in this Indenture. In case an Event
of Default has occurred (which has not been cured or waived), the Trustee shall exercise such of the rights and powers vested in it by this Indenture, and use the same degree of care and skill in their exercise, as a prudent person would exercise or
use under the circumstances in the conduct of his own affairs. 

  
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 (b)         No provision of this
Indenture shall be construed to relieve the Trustee from liability for its own negligent action, its own negligent failure to act or its own willful misconduct, except that: 

(i)         prior to the occurrence of an Event of Default and after the curing or
waiving of all Events of Default which may have occurred: 
 (A)         the duties
and obligations of the Trustee shall be determined solely by the express provisions of this Indenture and applicable law, and the Trustee shall not be liable except for the performance of such duties and obligations as are specifically set forth in
this Indenture and no implied covenants or obligations shall be read into this Indenture against the Trustee; and 
 (B)
        in the absence of bad faith and willful misconduct on the part of the Trustee, the Trustee may conclusively rely as to the truth of the statements and the correctness of the opinions expressed therein,
upon any certificates or opinions furnished to the Trustee and conforming to the requirements of this Indenture; but, in the case of any such certificates or opinions which by any provisions hereof are specifically required to be furnished to the
Trustee, the Trustee shall be under a duty to examine the same to determine whether or not they conform to the requirements of this Indenture (but need not confirm or investigate the accuracy of any mathematical calculations or other facts stated
therein); 
 (ii)         the Trustee shall not be liable for any error of judgment
made in good faith by a Trust Officer or Officers of the Trustee, unless the Trustee was negligent in ascertaining the pertinent facts; 

(iii)         the Trustee shall not be liable with respect to any action taken or
omitted to be taken by it in good faith in accordance with the written direction of the Holders of not less than a majority in principal amount of the Notes at the time outstanding determined as provided in Section 1.05 relating to the time, method
and place of conducting any proceeding for any remedy available to the Trustee, or exercising any trust or power conferred upon the Trustee, under this Indenture; 

(iv)         whether or not therein provided, every provision of this Indenture
relating to the conduct or affecting the liability of, or affording protection to, the Trustee shall be subject to the provisions of this Section 11.01; 

(v)         the Trustee shall not be liable in respect of any payment (as to the
correctness of amount, entitlement to receive or any other matters relating to payment) or notice effected by the Issuer or any Paying Agent or any records maintained by any co-Registrar with respect to the Notes; and 

(vi)         if any party fails to deliver a notice relating to an event the fact of
which, pursuant to this Indenture, requires notice to be sent to the Trustee, the Trustee may conclusively rely on its failure to receive such notice as reason to act as if no such event occurred. 

None of the provisions contained in this Indenture shall require the Trustee to expend or risk its own funds or otherwise incur personal
financial liability in the performance of any of its duties or in the exercise of any of its rights or powers, if there is reasonable ground for believing that the repayment of such funds or adequate indemnity against such risk or liability is not
reasonably assured to it. 

  
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 Section 11.02   Notice of Defaults. The Trustee shall give the Holders
notice of any Default of which a Trust Officer of the Trustee has knowledge or is deemed to have notice under Section 11.03(a) within 90 days after the occurrence thereof so long as such Default is continuing; provided, that (except in the case of
any Default in the payment of principal amount of, or interest on, any of the Notes or Fundamental Change Repurchase Price, Redemption Price or a default in the delivery of the Exchange Consideration), the Trustee shall be protected in withholding
such notice if and so long as it in good faith determines that the withholding of such notice is in the interest of the Holders of Notes. 

Section 11.03  Reliance on Documents, Opinions, Etc. Except as otherwise provided in Section 11.01: 

(a)         the Trustee may conclusively rely and shall be protected in acting upon
any resolution, certificate, statement, instrument, opinion, report, notice, request, consent, order, bond, debenture, note, coupon or other paper or document (whether in its original or facsimile form) believed by it in good faith to be genuine and
to have been signed or presented by the proper party or parties; 
 (b)         any
request, direction, order or demand of the Issuer mentioned herein shall be sufficiently evidenced by an Officer’s Certificate (unless other evidence in respect thereof be herein specifically prescribed); and any resolution of the Board of
Directors may be evidenced to the Trustee by a copy thereof certified by the Secretary, any Assistant Secretary or the General Counsel of the Issuer; 

(c)         the Trustee may consult with counsel of its own selection and any advice
or Opinion of Counsel shall be full and complete authorization and protection in respect of any action taken or omitted by it hereunder in good faith and in accordance with such advice or Opinion of Counsel; 

(d)         the Trustee shall be under no obligation to exercise any of the rights or
powers vested in it by this Indenture at the request, order or direction of any of the Holders pursuant to the provisions of this Indenture (including upon the occurrence and during the continuance of an Event of Default), unless such Holders shall
have offered to the Trustee security or indemnity satisfactory to it against any loss, expenses and liabilities which may be incurred therein or thereby; 

(e)         the Trustee shall not be bound to make any investigation into the facts or
matters stated in any resolution, certificate, statement, instrument, opinion, report, notice, request, direction, consent, order, bond, debenture or other paper or document, but the Trustee, in its discretion, may make such further inquiry or
investigation into such facts or matters as it may see fit, and, if the Trustee shall determine to make such further inquiry or investigation, it shall be entitled to examine the books, records and premises of the Issuer, personally or by agent or
attorney (at the reasonable expense of the Issuer and shall incur no liability of any kind by reason of such inquiry or investigation); 

  
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 (f)         the Trustee may execute any
of the trusts or powers hereunder or perform any duties hereunder either directly or by or through agents or attorneys and the Trustee shall not be responsible for any misconduct or negligence on the part of any agent or attorney appointed by it
with due care hereunder; 
 (g)         the Trustee shall not be liable for any
action taken, suffered, or omitted to be taken by it in good faith and reasonably believed by it to be authorized or within the discretion or rights or powers conferred upon it by this Indenture; 

(h)         in no event shall the Trustee be responsible or liable for special,
indirect, consequential or punitive loss or damage of any kind whatsoever (including, but not limited to, loss of profit) irrespective of whether the Trustee has been advised of the likelihood of such loss or damage and regardless of the form of
action; 
 (i)         the Trustee shall not be deemed to have notice of any Default
or Event of Default unless a Trust Officer of the Trustee has actual knowledge thereof or unless written notice of any event which is in fact such a default is received by the Trustee at the Corporate Trust Office of the Trustee, and such notice
references the Notes and the Indenture; 
 (j)         the rights, privileges,
protections, immunities and benefits given to the Trustee, including, without limitation, its right to be indemnified, are extended to, and shall be enforceable by, the Trustee in each of its capacities hereunder, and each agent, custodian and other
Person employed to act hereunder; 
 (k)         the Trustee shall not be required
to give any bond or surety in respect of the performance of its powers and duties hereunder; and 
 (l)
        the Trustee may request that the Issuer deliver a certificate setting forth the names of individuals and/or titles of officers authorized at such time to take specified actions pursuant to this
Indenture. 
 Section 11.04   No Responsibility for Recitals, Etc. The recitals contained herein and in the Notes
(except in the Trustee’s certificate of authentication) shall be taken as the statements of the Issuer, and the Trustee assumes no responsibility for the correctness of the same. The Trustee makes no representations as to the validity or
sufficiency of this Indenture or of the Notes. The Trustee shall not be accountable for the use or application by the Issuer of any Notes or the proceeds of any Notes authenticated and delivered by the Trustee in conformity with the provisions of
this Indenture. 
 Section 11.05   Trustee, Paying Agents, Exchange Agents or Registrar May Own Notes. The Trustee,
any Paying Agent, any Exchange Agent or Registrar, in its individual or any other capacity, may become the owner or pledgee of Notes with the same rights it would have if it were not Trustee, Paying Agent, Exchange Agent or Registrar. 

Section 11.06   Monies to be Held in Trust. Subject to the provisions of Section 13.04, all monies and properties
received by the Trustee shall, until used or applied as herein provided, be held in trust for the purposes for which they were received. Money held by the Trustee in trust 

  
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hereunder need not be segregated from other funds except to the extent required by law. The Trustee shall be under no liability for interest on any money received by it hereunder except as may be
agreed in writing from time to time by the Issuer and the Trustee. 
 Section 11.07  Compensation and Expenses of
Trustee. The Issuer covenants and agrees to pay to the Trustee from time to time, and the Trustee shall be entitled to, such compensation for all services rendered by it hereunder in any capacity (which shall not be limited by any provision of
law in regard to the compensation of a trustee of an express trust) as mutually agreed to from time to time in writing between the Issuer and the Trustee, and the Issuer will pay or reimburse the Trustee upon its request for all reasonable expenses,
disbursements and advances reasonably incurred or made by the Trustee in accordance with any of the provisions of this Indenture (including the reasonable compensation and the expenses and disbursements of its counsel and of all Persons not
regularly in its employ) except any such expense, disbursement or advance as may arise from its negligence or willful misconduct. The Issuer also covenants to indemnify the Trustee (or any officer, director or employee of the Trustee), in any
capacity under this Indenture and its agents and any authenticating agent for, and to hold them harmless against, any and all loss, liability, claim or expense incurred without negligence or willful misconduct on the part of the Trustee or such
officers, directors, employees and agent or authenticating agent, as the case may be, and arising out of or in connection with the acceptance or administration of this trust or in any other capacity hereunder (including, without limitation, in
respect of any payment of the Redemption Price in connection with the ability of Holders to surrender Notes for exchange during the period specified in Section 7.01(d), as the case may be, in connection with the Issuer’s election to effect a
Tax Redemption or a Provisional Redemption, as the case may be), including the costs and expenses of defending themselves against any claim (whether asserted by the Issuer, the Guarantor, a Holder or any other Person) of liability in the premises.
The obligations of the Issuer under this Section 11.07 to compensate or indemnify the Trustee and to pay or reimburse the Trustee for expenses, disbursements and advances shall be secured by a lien prior to that of the Notes upon all property and
funds held or collected by the Trustee as such, except funds held in trust for the benefit of the Holders of particular Notes. The obligation of the Issuer under this Section 11.07 shall survive the satisfaction and discharge of this Indenture and
the resignation or removal of the Trustee. 
 When the Trustee and its agents and any authenticating agent incur expenses or render services
after an Event of Default specified in Section 9.01(a)(ix) with respect to the Issuer occurs, the expenses and the compensation for the services are intended to constitute expenses of administration under any bankruptcy, insolvency or similar laws.

 Section 11.08  Officer’s Certificate as Evidence. Except as otherwise provided in Section 11.01, whenever in
the administration of the provisions of this Indenture the Trustee shall deem it necessary or desirable that a matter be proved or established prior to taking or omitting any action hereunder, such matter (unless other evidence in respect thereof be
herein specifically prescribed) may, in the absence of negligence or willful misconduct on the part of the Trustee, be deemed to be conclusively proved and established by an Officer’s Certificate delivered to the Trustee. 

Section 11.09  Conflicting Interests of Trustee. If the Trustee has or shall acquire a conflicting interest within the
meaning of the Trust Indenture Act, the Trustee shall either eliminate such interest or resign, to the extent and in the manner provided by, and subject to the provisions of, this Indenture. 

  
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 Section 11.10   Eligibility of Trustee. There shall at all times be a
Trustee hereunder which shall be a Person that is eligible pursuant to the Trust Indenture Act to act as such and has a combined capital and surplus of at least $50.0 million (or if such Person is a member of a bank holding company system, its bank
holding company shall have a combined capital and surplus of at least $50.0 million). If such Person publishes reports of condition at least annually, pursuant to law or to the requirements of any supervising or examining authority, then for the
purposes of this Section the combined capital and surplus of such Person shall be deemed to be its combined capital and surplus as set forth in its most recent report of condition so published. If at any time the Trustee shall cease to be eligible
in accordance with the provisions of this Section 11.10, it shall resign immediately in the manner and with the effect hereinafter specified in this Article. 

Section 11.11   Resignation or Removal of Trustee. 

(a)         The Trustee may at any time resign by giving written notice of such
resignation to the Issuer and to the Holders of Notes. Upon receiving such notice of resignation, the Issuer shall promptly appoint a successor trustee by written instrument, in duplicate, executed by order of the Board of Directors, one copy of
which instrument shall be delivered to the resigning Trustee and one copy to the successor trustee. If no successor trustee shall have been so appointed and have accepted appointment sixty (60) days after the mailing of such notice of
resignation to the Holders, the resigning Trustee may, upon ten (10) Business Days’ notice to the Issuer and the Holders, appoint a successor identified in such notice or may petition, at the expense of the Issuer, any court of competent
jurisdiction for the appointment of a successor trustee, or, if any Holder who has been a bona fide Holder of a Note or Notes for at least six (6) months (or, if earlier, the date of this Indenture) may, subject to the provisions of Section
9.16, on behalf of himself and all others similarly situated, petition any such court for the appointment of a successor trustee. Such court may thereupon, after such notice, if any, as it may deem proper and prescribe, appoint a successor trustee.

 (b)         In case at any time any of the following shall occur: 

(i)         the Trustee shall fail to comply with Section 11.09 after written request
therefor by the Issuer or by any Holder who has been a bona fide Holder of a Note or Notes for at least six (6) months (or, if earlier, the date of this Indenture); or 

(ii)         the Trustee shall cease to be eligible in accordance with the provisions
of Section 11.10 and shall fail to resign after written request therefor by the Issuer or by any such Holder; or 

(iii)        the Trustee shall become incapable of acting, or shall be adjudged a
bankrupt or insolvent, or a receiver of the Trustee or of its property shall be appointed, or any public officer shall take charge or control of the Trustee or of its property or affairs for the purpose of rehabilitation, conservation or
liquidation; 

  
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then, in any such case, the Issuer may remove the Trustee and appoint a successor trustee by written instrument, in duplicate, executed by order of the Board of Directors, one copy of which
instrument shall be delivered to the Trustee so removed and one copy to the successor trustee, or, subject to the provisions of Section 9.16, any Holder who has been a bona fide Holder of a Note or Notes for at least six (6) months (or, if
earlier, the date of this Indenture) may, on behalf of himself and all others similarly situated, petition any court of competent jurisdiction for the removal of the Trustee and the appointment of a successor trustee; provided, however, that
if no successor Trustee shall have been appointed and have accepted appointment sixty (60) days after either the Issuer or the Holders has removed the Trustee, the Trustee so removed may petition at the Issuer’s expense any court of
competent jurisdiction for an appointment of a successor trustee. Such court may thereupon, after such notice, if any, as it may deem proper and prescribe, remove the Trustee and appoint a successor trustee. 

(c)         The Holders of a majority in aggregate principal amount of the Notes at
the time outstanding may at any time remove the Trustee and nominate a successor trustee which shall be deemed appointed as successor trustee unless, within ten (10) days after notice to the Issuer of such nomination, the Issuer objects
thereto, in which case the Trustee so removed or any Holder, or if such Trustee so removed or any Holder fails to act, the Issuer, upon the terms and conditions and otherwise as in Section 11.11(a) provided, may petition any court of competent
jurisdiction for an appointment of a successor trustee. 
 (d)         Any
resignation or removal of the Trustee and appointment of a successor trustee pursuant to any of the provisions of this Section 11.11 shall become effective upon acceptance of appointment by the successor trustee as provided in Section 11.12. 

Section 11.12   Acceptance by Successor Trustee. Any successor trustee appointed as provided in Section 11.11 shall
execute, acknowledge and deliver to the Issuer and to its predecessor trustee an instrument accepting such appointment hereunder, and thereupon the resignation or removal of the predecessor trustee shall become effective and such successor trustee,
without any further act, deed or conveyance, shall become vested with all the rights, powers, duties and obligations of its predecessor hereunder, with like effect as if originally named as trustee herein; but, nevertheless, on the written request
of the Issuer or of the successor trustee, the trustee ceasing to act shall, upon payment of any amount then due it pursuant to the provisions of Section 11.07, execute and deliver an instrument transferring to such successor trustee all the rights
and powers of the trustee so ceasing to act. Upon request of any such successor trustee, the Issuer shall execute any and all instruments in writing for more fully and certainly vesting in and confirming to such successor trustee all such rights and
powers. Any trustee ceasing to act shall, nevertheless, retain a lien upon all property and funds held or collected by such trustee as such, except for funds held in trust for the benefit of Holders of particular Notes, to secure any amounts then
due it pursuant to the provisions of Section 11.07. 
 No successor trustee shall accept appointment as provided in this Section 11.12
unless, at the time of such acceptance, such successor trustee shall be qualified under the provisions of Section 11.09 and be eligible under the provisions of Section 11.10. 

  
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 Upon acceptance of appointment by a successor trustee as provided in this Section 11.12, the
Issuer (or the former trustee, at the written direction of the Issuer) shall mail or cause to be mailed notice of the succession of such trustee hereunder to the Holders of Notes at their addresses as they shall appear on the Register. If the Issuer
fails to mail such notice within ten (10) days after acceptance of appointment by the successor trustee, the successor trustee shall cause such notice to be mailed at the expense of the Issuer. 

Section 11.13   Succession by Merger, Etc. Any corporation into which the Trustee may be merged or exchanged or with
which it may be consolidated, or any corporation resulting from any merger, exchange or consolidation to which the Trustee shall be a party, or any corporation succeeding to all or substantially all of the corporate trust business of the Trustee
(including any trust created by this Indenture), shall be the successor to the Trustee hereunder without the execution or filing of any paper or any further act on the part of any of the parties hereto, provided that in the case of any corporation
succeeding to all or substantially all of the corporate trust business of the Trustee, such corporation shall be qualified under the provisions of Section 11.09 and eligible under the provisions of Section 11.10. 

In case at the time such successor to the Trustee shall succeed to the trusts created by this Indenture, any of the Notes shall have been
authenticated but not delivered, any such successor to the Trustee may adopt the certificate of authentication of any predecessor trustee or authenticating agent appointed by such predecessor trustee, and deliver such Notes so authenticated; and in
case at that time any of the Notes shall not have been authenticated, any successor to the Trustee or any authenticating agent appointed by such successor trustee may authenticate such Notes in the name of the successor trustee; and in all such
cases such certificates shall have the full force that is provided in the Notes or in this Indenture; provided, however, that the right to adopt the certificate of authentication of any predecessor Trustee or authenticate Notes in the name of any
predecessor Trustee shall apply only to its successor or successors by merger, exchange or consolidation. 
 Section 11.14  
Preferential Collection of Claims. If and when the Trustee shall be or become a creditor of the Issuer (or any other obligor upon the Notes), the Trustee shall be subject to the provisions of the Trust Indenture Act regarding the collection
of the claims against the Issuer (or any such other obligor). 
 Section 11.15   Trustee’s Application for
Instructions from the Issuer. Any application by the Trustee for written instructions from the Issuer (other than with regard to any action proposed to be taken or omitted to be taken by the Trustee that affects the rights of the Holders of the
Notes under this Indenture) may, at the option of the Trustee, set forth in writing any action proposed to be taken or omitted by the Trustee under this Indenture and the date on and/or after which such action shall be taken or such omission shall
be effective. The Trustee shall not be liable for any action taken by, or omission of, the Trustee in accordance with a proposal included in such application on or after the date specified in such application (which date shall not be less than three
(3) Business Days after the date any officer of the Issuer actually receives such application, unless any such officer shall have consented in writing to any earlier date) unless prior to taking any such action (or the effective date in the
case of an omission), the Trustee shall have received written instructions in response to such application specifying the action to be taken or omitted. 

  
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 ARTICLE 12 

HOLDERS’ LISTS AND REPORTS BY TRUSTEE 

Section 12.01  Issuer to Furnish Trustee Names and Addresses of Holders. The Issuer will furnish or cause to be
furnished to the Trustee: 
 (a)         semiannually, not more than 15 days after
each Regular Record Date, a list, in such form as the Trustee may reasonably require, of the names and addresses of the Holders as of such Regular Record Date; and 

(b)         at such other times as the Trustee may request in writing, within 30 days
after the receipt by the Issuer of any such request, a list of similar form and content as of a date not more than 15 days prior to the time such list is furnished; 

excluding from any such list names and addresses received by the Trustee in its capacity as Registrar; provided, however, that no such list need
be furnished so long as the Trustee is acting as Registrar. 
 Section 12.02  Preservation of Information; Communications
to Holders. 
 (a)         The Trustee shall preserve, in as current a form as
is reasonably practicable, the names and addresses of Holders contained in the most recent list furnished to the Trustee as provided in Section 12.01 and the names and addresses of Holders received by the Trustee in its capacity as Registrar. The
Trustee may destroy any list furnished to it as provided in Section 12.01 upon receipt of a new list so furnished. 
 (b)
        The rights of Holders to communicate with other Holders with respect to their rights under this Indenture or under the Notes, and the corresponding rights and duties of the Trustee, shall be as
provided under applicable law. 
 (c)         Every Holder, by receiving and holding
the same, agrees with the Issuer and the Trustee that neither the Issuer nor the Trustee nor any agent of either of them shall be held accountable by reason of any disclosure of information as to names and addresses of Holders made pursuant to
applicable law. 
 Section 12.03  Reports By Trustee. 

(a)         The Trustee shall transmit to Holders such reports concerning the Trustee
and its actions under this Indenture as may be required pursuant to this Indenture at the times and in the manner provided pursuant thereto. 

(b)         To the extent required pursuant to the Trust Indenture Act, a copy of each
such report shall, at the time of such transmission to Holders, be filed by the Trustee with each stock exchange, if any, upon which the Notes are listed, with the Commission and with the Issuer. The Issuer will notify the Trustee in writing when
the Notes are listed on any stock exchange or of any delisting thereof. 

  
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 ARTICLE 13 

SATISFACTION AND DISCHARGE 

Section 13.01  Discharge of Liability on Notes. When (a)(i) the Issuer delivers to the Registrar all outstanding Notes
(other than Notes replaced pursuant to Section 3.08) for cancellation or (ii) all outstanding Notes have become due and payable, whether on the Maturity Date, any Fundamental Change Repurchase Date, any Redemption Date, upon exchange,
redemption, declaration of acceleration or otherwise, and the Issuer irrevocably deposits with the Trustee or the Guarantor delivers to the Holders, as applicable, cash, Ordinary Shares or a combination thereof, as applicable (solely to satisfy any
outstanding Exchange Obligation with respect to the Notes), sufficient to pay or deliver, as the case may be, all amounts due and owing on all outstanding Notes (other than Notes replaced pursuant to Section 3.08), (b) the Issuer pays all other
sums payable by it under this Indenture and (c) the Issuer delivers to the Trustee an Officer’s Certificate and Opinion of Counsel stating that the conditions precedent therefor have been satisfied, then, the Notes and this Indenture (with
respect to the Notes) will cease to be of further effect and the Holders and the Trustee will acknowledge the satisfaction and discharge of this Indenture with respect to the Notes; provided, however, that any obligation of the Issuer to the Trustee
under Sections 11.06 or 11.07 shall survive after the Notes are paid in full and there are no Notes outstanding. 

Section 13.02  Deposited Moneys to Be Held in Trust. Subject to Section 13.04 hereof, all cash, Ordinary Shares or a
combination thereof, as applicable, deposited with the Trustee pursuant to Section 13.01 hereof will be held in trust for the sole benefit of the Holders, and such cash, Ordinary Shares or a combination thereof, as applicable, will be applied by the
Trustee, either directly or through the Paying Agent, to the payment of the obligation for which such cash, Ordinary Shares or a combination thereof, as applicable, have been deposited with the Trustee. 

Section 13.03  Paying Agent to Repay Monies Held. Upon the satisfaction and discharge of this Indenture, all cash and
Ordinary Shares, if any, then held by the Paying Agent (if other than the Trustee) shall, upon written request of the Issuer, be repaid to it or paid to the Trustee, and thereupon such Paying Agent shall be released from all further liability with
respect to such monies and Ordinary Shares, if any. 
 Section 13.04  Repayment to the Issuer. Subject to any
applicable unclaimed property law, the Trustee and the Paying Agent, upon receiving a written request from the Issuer, will promptly turn over to the Issuer any cash or Ordinary Shares held for payment on the Notes that remains unclaimed two years
after the date on which such payment was due. After the Trustee and the Paying Agent return such cash and Ordinary Shares, the Trustee and the Paying Agent will have no further liability to any Holder with respect to such cash and Ordinary Shares,
and any Holder entitled to the payment of such cash or Ordinary Shares under the Notes or this Indenture must look to the Issuer for payment as general creditor of the Issuer. 

Section 13.05  Reinstatement. If the Trustee or the Paying Agent is unable to apply any cash or Ordinary Shares in
accordance with Section 13.02 hereof by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise prohibiting such application, the Issuer’s obligations under this Indenture and the Notes shall
be revived and reinstated as though no deposit had occurred pursuant to Section 13.01 until such time as the 

  
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Trustee or the Paying Agent is permitted to apply all such cash, Ordinary Shares or a combination thereof, as applicable, in accordance with Section 13.02 hereof; provided, however, that if the
Issuer makes any payment of the principal of, interest (including Additional Interest, if any) on, Fundamental Change Repurchase Price or Redemption Price for, Additional Amounts with respect to or cash portion of the Exchange Obligation with
respect to, any Note following the reinstatement of its obligations, the Issuer shall be subrogated to the rights of the Holders to receive such payment from any cash, Ordinary Shares or a combination thereof, as applicable, held by the Trustee or
Paying Agent. 
 ARTICLE 14 

SUPPLEMENTAL INDENTURES 

Section 14.01  Without Consent of Holders. The Issuer, the Guarantor and the Trustee may amend or supplement this
Indenture or the Notes without the consent of any Holder, including to: 
 (a)
        cure any ambiguity, omission, inconsistency or correct or supplement any defective provision contained in this Indenture that does not in the good faith opinion of the Board of Directors or the
Guarantor’s Board of Directors adversely affect the interests of the Holders of the Notes in any material respect; 

(b)         evidence a successor to the Issuer or the Guarantor and the assumption by
that successor of the Issuer’s obligations or the Guarantor’s obligations, as applicable, under the Indenture and under the Notes; 

(c)         to add guarantees with respect to the Notes; 

(d)         secure the Issuer’s or the Guarantor’s obligations in respect of
the Notes; 
 (e)         add to the Issuer’s covenants or Events of Default
for the benefit of the Holders or surrender any right or power conferred upon the Issuer or the Guarantor; 
 (f)
        make any change that does not adversely affect the rights of any Holder; 

(g)         increase the Exchange Rate as provided in the Indenture; 

(h)         in connection with any Merger Event, provide that the Notes are
convertible into Reference Property, subject to the provisions of Section 7.03, and make such related changes to the terms of the Notes to the extent expressly required by Section 7.07. 

(i)         provide for the acceptance of the appointment of a successor Trustee or
facilitate the administration of the trusts under this Indenture by more than one Trustee, in each case in accordance with this Indenture; or 

(j)         conform the provisions of this Indenture or the Notes to any provision of
the “Description of Notes” section of the Offering Memorandum. 

  
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 Section 14.02  With Consent of Holders. With the written consent of the
Holders of at least a majority in principal amount of then outstanding Notes (including, without limitation, consents obtained in connection with a repurchase of, or tender offer or exchange offer for, the Notes), the Issuer, when authorized by the
resolutions of the Board of Directors and the Trustee, at the Issuer’s expense, may from time to time and at any time enter into an indenture or indentures supplemental hereto for the purposes of adding any provisions to or changing in any
manner, waiving or eliminating any of the provisions of this Indenture or the Notes or any supplemental indenture or of modifying in any manner the rights of the Holders; provided, however, that, without the consent of each Holder of a then
outstanding Note affected, no amendment or supplement to this Indenture or the Notes may: 
 (a)
        reduce the amount of Notes whose Holders must consent to an amendment; 

(b)         reduce the rate of or extend the stated time for payment of interest on
any Note; 
 (c)         reduce the principal of or extend the stated maturity of
any Note; 
 (d)         except as otherwise required herein, to make any change
that adversely affects the Exchange Rights of any Note; 
 (e)         reduce the
Fundamental Change Repurchase Price or Redemption Price of any Note or amend or modify in any manner adverse to the Holders of Notes the Issuer’s or the Guarantor’s obligation to make such payments, whether through an amendment or waiver
of provisions of the covenants, definitions or otherwise; 
 (f)         make any
Note payable in money, or at a place of payment other than that stated in the Note; 
 (g)
        change the ranking of the Notes or the Guarantee; 
 (h)
        impair the right of any Holder to receive payment of principal (including the Fundamental Change Repurchase Price or Redemption Price, if applicable) and interest on such Holder’s Notes on or
after the due dates therefor or to institute suit for the enforcement of any payment on or with respect to any Note or with respect to such Holder’s Notes; 

(i)         make any change in this Section 14.02 or in the provisions relating to the
waiver of particular past Events of Default or particular covenants; 
 (j)
        change the Issuer’s obligations under Section 4.10; or 
 (k)
        release the Guarantor from, or modify or affect in any manner adverse to the Holders the terms and conditions of, the obligations of the Guarantor under the Guarantee. 

  
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 It will not be necessary for the consent of the Holders under this Section 14.02 to approve the
particular form of any proposed amendment, but it will be sufficient if such consent approves the substance of such proposed amendment. 

Section 14.03  Notices of Supplemental Indentures. After an amendment or supplement to this Indenture or the Notes
pursuant to this Article 14 becomes effective, the Issuer will mail to the Holders a notice briefly describing such amendment or supplement to this Indenture. However, the failure to give such notice to all Holders, or any defect in such notice,
will not impair or affect the validity of such amendment or supplement to this Indenture. 
 Section 14.04  Execution of
Supplemental Indentures. In executing, or accepting the additional trusts created by, any supplemental indenture permitted by this Article or the modification thereby of the trusts created by this Indenture, the Trustee shall receive, and shall
be fully protected in relying upon, an Officer’s Certificate and an Opinion of Counsel stating that the execution of such supplemental indenture is authorized or permitted by this Indenture and that such supplemental indenture is the legal,
valid and binding obligation of the Issuer, enforceable against the Issuer in accordance with its terms. The Trustee may, but shall not be obligated to, enter into any such supplemental indenture which affects the Trustee’s own rights, duties
or immunities under this Indenture or otherwise. 
 ARTICLE 15 

GUARANTEE 

Section 15.01  Guarantee. By its execution hereof, the Guarantor acknowledges and agrees that it receives substantial
benefits from the Issuer and the issuance of the Notes and that the Guarantor is providing its Guarantee for good and valuable consideration, including, without limitation, such substantial benefits. Accordingly, subject to the provisions of this
Article 15, the Guarantor hereby fully and unconditionally guarantees as a primary principal obligation and not merely as a surety to each Holder and its successors and assigns that: (x) the principal of (including the Redemption Price and
Fundamental Change Repurchase Price), Additional Amounts with respect to, Exchange Obligation with respect to, and interest, if any, on the Notes shall be duly and punctually paid in full and/or performed in accordance with the terms of this
Indenture when due, whether at the Maturity Date, upon declaration of acceleration, upon redemption, upon required repurchase, upon exchange or otherwise, along with any interest on overdue principal, interest, Additional Amounts and (to the extent
permitted by law) interest on any interest, if any, on the Notes and (y) in case of any extension of time of payment or renewal of any Notes or any of such other obligations, the same shall be duly and punctually paid in full and/or performed
in accordance with the terms of this Indenture when due or performed in accordance with the terms of the extension or renewal, whether at the Maturity Date, upon declaration of acceleration, upon redemption, upon required repurchase, upon exchange
or otherwise, along with any interest on overdue principal, interest, Additional Amounts and (to the extent permitted by law) interest on any interest, if any, on the Notes. Furthermore, subject to the provisions of this Article 15, the Guarantor
hereby unconditionally guarantees to the Trustee and to each Holder and their respective successors and assigns that (z) all other obligations of the Issuer to the Holders or the Trustee hereunder or under the Notes (including fees, expenses or
other) shall be promptly paid in full or performed, all in accordance with the terms hereof, subject, however, in the case of clauses (x), (y) and (z) above, to the limitations set forth in


  
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Section 15.03 hereof (the obligations set forth in this Section 15.01 collectively, the “Guarantee Obligations”). The Guarantee constitutes a general unsecured and unsubordinated
obligation of the Guarantor. 
 Subject to the provisions of this Article 15, the Guarantor hereby agrees that its Guarantee hereunder shall
be unconditional, irrespective of the validity, regularity or enforceability of the Notes or this Indenture, the absence of any action to enforce the same, any waiver or consent by any Holder of the Notes with respect to any thereof, the entry of
any judgment against the Issuer, any action to enforce the same or any other circumstance which might otherwise constitute a legal or equitable discharge or defense of the Guarantor. The Guarantor hereby waives and relinquishes: (a) any right
to require the Trustee, the Holders or the Issuer (each, a “Benefited Party”) to proceed against the Issuer or any other Person or to proceed against or exhaust any security held by a Benefited Party at any time or to pursue any
other remedy in any secured party’s power before proceeding against the Guarantor; (b) any defense that may arise by reason of the incapacity, lack of authority, death or disability of any other Person or Persons or the failure of a
Benefited Party to file or enforce a claim against the estate (in administration, bankruptcy or any other proceeding) of any other Person or Persons; (c) demand, protest and notice of any kind (except as expressly required by this Indenture),
including but not limited to notice of the existence, creation or incurring of any new or additional indebtedness or obligation or of any action or non-action on the part of the Guarantor, the Issuer, any Benefited Party, any creditor of the
Guarantor or the Issuer or on the part of any other Person whomsoever in connection with any obligations the performance of which are hereby guaranteed; (d) any defense based upon an election of remedies by a Benefited Party, including but not
limited to an election to proceed against the Guarantor for reimbursement; (e) any defense based upon any statute or rule of law which provides that the obligation of a surety must be neither larger in amount nor in other respects more
burdensome than that of the principal; (f) any defense arising because of a Benefited Party’s election, in any proceeding instituted under Bankruptcy Law, of the application of Section 1111(b)(2) of the Bankruptcy Code or any similar
provision (including under Irish or Bermuda law); and (g) any defense based on any borrowing or grant of a security interest under Section 364 of the Bankruptcy Code or any similar provision (including under Irish or Bermuda law). The
Guarantor hereby covenants that, except as otherwise provided therein, the Guarantee shall not be discharged except by payment in full of all Guarantee Obligations, including the principal (including the Fundamental Change Repurchase Price and
Redemption Price, if applicable), Additional Amounts, Exchange Obligations and interest on the Notes and all other costs provided for under this Indenture or as provided in Article 11. 

The Guarantor as principal obligor and as a separate and independent obligation and liability from its other obligations and liabilities under
this Indenture agrees to indemnify and keep indemnified each Holder and the Trustee in full and on demand in respect of the performance and discharge of the Guarantee Obligations (except where the Issuer’s failure to perform or discharge the
Guarantee Obligations results from such Holder’s failure to comply with its obligations under the Indenture or the Trustee’s negligence or willful misconduct or the Issuer contesting any payment or part of a payment in good faith). 

If any Holder or the Trustee is required by any court or otherwise to return to either the Issuer or the Guarantor, or any trustee or similar
official acting in relation to either the Issuer or 

  
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the Guarantor, any amount paid by the Issuer or the Guarantor to the Trustee or such Holder, then the Guarantee, to the extent theretofore discharged, shall be reinstated in full force and
effect. The Guarantor agrees that it shall not be entitled to any right of subrogation in relation to the Holders in respect of any Guarantee Obligations hereby until payment in full of all such obligations guaranteed hereby. The Guarantor agrees
that, as between it, on the one hand, and the Holders and the Trustee, on the other hand, (x) the maturity of the obligations guaranteed hereby may be accelerated as provided in Article 9 hereof for the purposes hereof, notwithstanding any
stay, injunction or other prohibition preventing such acceleration in respect of the Guarantee Obligations, and (y) in the event of any acceleration of such obligations as provided in Article 9 hereof, such Guarantee Obligations (whether or not
due and payable) shall forthwith become due and payable by the Guarantor for the purpose of the Guarantee. 
 The Issuer and the Guarantor
acknowledge that the allotment and issue of Ordinary Shares and the delivery of Ordinary Shares, if any, hereunder (whether upon exchange, under the terms of the Guarantee or otherwise) by the Guarantor (or by the Ordinary Share Depositary at the
direction of the Guarantor) will create an equivalent debt owing from the Issuer to the Guarantor. 

Section 15.02  Limitation of Guarantor’s Liability; Certain Bankruptcy Events. 

(a)         The Guarantor, and by its acceptance hereof each Holder, hereby confirms
that it is the intention of all such parties that the Guarantee Obligations of the Guarantor pursuant to its Guarantee not constitute a fraudulent transfer or conveyance for purposes of any Bankruptcy Law, the Uniform Fraudulent Conveyance Act, the
Uniform Fraudulent Transfer Act or any similar federal or state law. To effectuate the foregoing intention, the Holders and the Guarantor hereby irrevocably agree that the Guarantee Obligations of the Guarantor under this Article 15 shall be limited
to the maximum amount as shall, after giving effect to all other contingent and fixed liabilities of the Guarantor, result in the Guarantee Obligations of the Guarantor under the Guarantee not constituting a fraudulent transfer or conveyance. 

(b)     The Guarantor hereby covenants and agrees, to the fullest extent that it may do so under
applicable law, that in the event of the insolvency, bankruptcy, dissolution, liquidation or reorganization of the Issuer, the Guarantor shall not file (or join in any filing of), or otherwise seek to participate in the filing of, any motion or
request seeking to stay or to prohibit (even temporarily) execution on the Guarantee and hereby waives and agrees not to take the benefit of any such stay of execution, whether under Section 362 or 105 of the Bankruptcy Code or otherwise. 

Section 15.03  Application of Certain Terms and Provisions to the Guarantor. 

(a)         For purposes of any provision of this Indenture which provides for the
delivery by the Guarantor of an Officer’s Certificate and/or an Opinion of Counsel, the definitions of such terms in Section 1.01 hereof shall apply to the Guarantor as if references therein to the Issuer or the Guarantor, as applicable, were
references to the Guarantor. 

  
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 (b)         Any request, direction, order
or demand which by any provision of this Indenture is to be made by the Guarantor shall be sufficient if evidenced as described in Section 11.03(b) hereof as if references therein to the Issuer were references to the Guarantor. 

(c)         Upon any demand, request or application by the Guarantor to the Trustee to
take any action under this Indenture, the Guarantor shall furnish to the Trustee such certificates and opinions as are required in Section 1.03 hereof as if all references therein to the Issuer were references to the Guarantor. 

ARTICLE 16 
 MISCELLANEOUS 

Section 16.01  Official Acts by Successor Corporation. Any act or proceeding by any provision of this Indenture
authorized or required to be done or performed by any board, committee or officer of the Issuer shall and may be done and performed with like force and effect by the like board, committee or officer of any Person that shall at the time be the lawful
sole successor of the Issuer or Guarantor. 
 Section 16.02  Notices. Any notice or communication shall be in writing
(including telecopy promptly confirmed in writing) and delivered in person or mailed by first-class mail addressed as follows: 
 if to the
Issuer: 
 Horizon Pharma Investment Limited 

HP House 
 21 Laffan Street 

Hamilton HM 09 
 Bermuda 

Attention: Secretary 
 with
copies to: 
 Horizon Pharma Public Limited Company 

Connaught House, 1st Floor 

1 Burlington Road 
 Dublin 4,
Ireland 
 Attention: Secretary 

if to Guarantor: 
 Horizon
Pharma Public Limited Company 
 Connaught House, 1st Floor 

1 Burlington Road 
 Dublin 4,
Ireland 
 Attention: Secretary 

  
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 with a copy to: 

Horizon Pharma Investment Limited 

Connaught House, 1st Floor 

1 Burlington Road 
 Dublin 4,
Ireland 
 Attention: Secretary 

if to the Trustee: 
 U.S. Bank
National Association 
 Global Corporate Trust Services 

Mailcode: EP-MN-WS3C 
 60
Livingston Avenue 
 St. Paul, MN 55107-2292 

Attention: Rick Prokosch – Horizon Pharma Corporate Trust Administrator 

Fax: (651) 466-7430 

Email: Rick.Prokosch@usbank.com 

The Issuer, the Guarantor or the Trustee by notice to the others may designate additional or different addresses for subsequent notices or
communications. 
 Any notice or communication mailed to a registered Holder shall be mailed to the Holder at the Holder’s address as
it appears on the registration books of the Registrar and shall be sufficiently given if so mailed within the time prescribed. 
 Failure to
mail a notice or communication to a Holder or any defect in it shall not affect its sufficiency with respect to other Holders. If a notice or communication is mailed in the manner provided above, it is duly given, whether or not the addressee
receives it, except that notices to the Trustee shall be effective only upon receipt. 
 The Trustee agrees to accept and act upon facsimile
transmission of written instructions and/or directions pursuant to this Indenture given by the Issuer; provided, however, that (i) the Issuer, subsequent to such facsimile transmission of written instructions and/or directions,
shall provide the originally executed instructions and/or directions to the Trustee in a timely manner and (ii) such originally executed instructions and/or directions shall be signed by an authorized officer of the Issuer. 

Section 16.03  Rules by Trustee, Paying Agent and Registrar. The Trustee may make reasonable rules for action by, or a
meeting of, Holders. The Registrar and the Paying Agent may make reasonable rules for their functions. 

Section 16.04  Governing Law. THIS INDENTURE AND THE NOTES, AND ANY CLAIM, CONTROVERSY OR DISPUTE ARISING UNDER OR
RELATED TO THIS INDENTURE OR THE NOTES, SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK. 

  
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 Section 16.05  No Recourse against Others. Except to the extent provided
otherwise herein, an incorporator, director, officer, employee, Affiliate or shareholder of the Issuer or the Guarantor, solely by reason of this status, shall not have any liability for any obligations of the Issuer or the Guarantor under the
Notes, this Indenture or for any claim based on, in respect of or by reason of such obligations or their creation. By accepting a Note, each Holder shall waive and release all such liability. The waiver and release shall be part of the consideration
for the issue of the Notes. 
 Section 16.06  Successors. All the covenants, stipulations, promises and agreements by
the Issuer or Guarantor contained in this Indenture shall bind their respective successors and assigns whether so expressed or not. 

Section 16.07  Multiple Originals. The parties may sign any number of copies of this Indenture. Each signed copy shall
be an original, but all of them together represent the same agreement. One signed copy is enough to prove this Indenture. Delivery of an executed counterpart by facsimile shall be effective as delivery of a manually executed counterpart thereof.

 Section 16.08  Benefits of Indenture. Nothing in this Indenture or in the Notes, express or implied, shall give to
any Person, other than the parties hereto and their respective successors hereunder and the Holders of Notes, any benefit or any legal or equitable right, remedy or claim under this Indenture. 

Section 16.09  Table of Contents; Headings. The table of contents, cross-reference sheet and headings of the Articles
and Sections of this Indenture have been inserted for convenience of reference only, are not intended to be considered a part hereof and shall not modify or restrict any of the terms or provisions hereof. 

Section 16.10  Severability Clause. In case any provision in this Indenture shall be invalid, illegal or unenforceable,
the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby and such provision shall be ineffective only to the extent of such invalidity, illegality or unenforceability. 

Section 16.11  Calculations. Except as otherwise provided herein, the Issuer will be responsible for making all
calculations called for under this Indenture or the Notes (including, without limitation, determinations of the Last Reported Sale Prices of the Ordinary Shares, accrued interest payable on the Notes, the Trading Price of the Notes and the Exchange
Rate of the Notes). The Issuer will make all such calculations in good faith and, absent manifest error, its calculations will be final and binding on Holders. The Issuer will provide a schedule of its calculations to each of the Trustee and the
Exchange Agent, and each of the Trustee and Exchange Agent is entitled to rely conclusively upon the accuracy of such calculations without independent verification. The Trustee will deliver a copy of such schedule to any Holder upon the written
request of such Holder. 
 Section 16.12  Waiver of Jury Trial. EACH OF THE ISSUER, THE GUARANTOR AND THE TRUSTEE
HEREBY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY AND ALL RIGHT TO TRIAL BY JURY IN ANY LEGAL PROCEEDING ARISING OUT OF OR RELATING TO THIS AGREEMENT, THE SECURITIES OR THE TRANSACTION CONTEMPLATED THEREBY. 

  
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 Section 16.13   Consent to Jurisdiction. 

(a)         Each of the Issuer and the Guarantor hereby irrevocably and
unconditionally submits, for itself and its property, to the nonexclusive jurisdiction of any New York State court or federal court of the United States sitting in the State and City of New York, County and Borough of Manhattan, and any appellate
court from any thereof, in any action or proceeding arising out of or relating to this Indenture or the Notes, or for recognition or enforcement of any judgment, and each of the parties hereto hereby irrevocably and unconditionally agrees that all
claims in respect of any such action or proceeding may be heard and determined in such state court sitting in the State and City of New York, County and Borough of Manhattan or, to the extent permitted by law, in such federal court sitting in the
State and City of New York, County and Borough of Manhattan. 
 (b)         Each of
the Issuer and the Guarantor hereby irrevocably and unconditionally waives, to the fullest extent it may legally and effectively do so, any objection which it may now or hereafter have to the laying of venue of any suit, action proceeding arising
out of or relating to this Indenture or the Notes in any New York State or federal court. Each of the parties hereto hereby irrevocably waives, to the fullest extent permitted by law, the defense of an inconvenient forum to the maintenance of such
action or proceeding in any such court. 
 Section 16.14   Judgment Currency. If for the purposes of obtaining
judgment in any court it is necessary to convert a sum due hereunder into any currency other than United States dollars, the parties hereto agree, to the fullest extent permitted by law, that the rate of exchange used shall be the rate at which in
accordance with normal banking procedures the Trustee could purchase United States dollars with such other currency in The City of New York on the Business Day preceding that on which final judgment is given. The obligation of the Issuer and the
Guarantor with respect to any sum due from it to the Trustee and the Holders shall, notwithstanding any judgment in a currency other than United States dollars, not be discharged until the first Business Day following receipt by the Trustee or the
Holders of any sum in such other currency, and only to the extent that the Trustee may in accordance with normal banking procedures purchase United States dollars with such other currency. If the United States dollars so purchased are less than the
sum originally due to the Trustee or the Holders, the Issuer and the Guarantor, jointly and severally, to the extent permitted by law, agree as a separate obligation and notwithstanding any such judgment, to indemnify the Trustee and such Holders
against such loss. If the United States dollars so purchased are greater than the sum originally due to the Trustee or the Holders, the Trustee and the Holders hereby agrees to pay to the Issuer and/or the Guarantor, as applicable, an amount equal
to the excess of the dollars so purchased over the sum originally due to such person. 
 Section 16.15   Force
Majeure. In no event shall the Trustee be responsible or liable for any failure or delay in the performance of its obligations hereunder arising out of or caused by, directly or indirectly, forces beyond its control, including, without
limitation, strikes, work 

  
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stoppages, accidents, acts of war or terrorism, civil or military disturbances, nuclear or natural catastrophes or acts of God, and interruptions, loss or malfunctions of utilities,
communications or computer (software or hardware) services; it being understood that the Trustee shall use reasonable efforts which are consistent with accepted practices in the banking industry to resume performance as soon as practicable under the
circumstances. 
 Section 16.16   U.S.A. Patriot Act. The parties hereto acknowledge that in accordance with
Section 326 of the U.S.A. Patriot Act, the Trustee, like all financial institutions and in order to help fight the funding of terrorism and money laundering, is required to obtain, verify, and record information that identifies each person or
legal entity that establishes a relationship or opens an account with the Trustee. The parties to this Indenture agree that they will provide the Trustee with such information as it may request in order for the Trustee to satisfy the requirements of
the U.S.A. Patriot Act. 
 [Remainder of the page intentionally left blank] 

  
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 IN WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed and
delivered as of the date first written above. 
  

			
	 HORIZON PHARMA INVESTMENT LIMITED, as Issuer

		
	By:		 /s/ David G. Kelly

			Name: David G. Kelly
			Title: Director


  

									
	GIVEN under the		)						
	common seal of		)		    				
	HORIZON PHARMA		)						
	PUBLIC LIMITED		)				(Common Seal)
	COMPANY		)						
			)						
			)				By:		 /s/ David G. Kelly

							Name: David G. Kelly
							Secretary

 [Signature Page to the Indenture – Issuer and Guarantor] 







 
			
	 U.S. BANK NATIONAL ASSOCIATION, as Trustee

		
	By:		 /s/ Richard Prokosch

			Name: Richard Prokosch
			Title: Vice President


 [Signature Page to the Indenture – Trustee] 







 EXHIBIT A 

[FORM OF RESTRICTED STOCK LEGEND] 

THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE
OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE FOLLOWING SENTENCE. BY ITS ACQUISITION HEREOF OR OF A BENEFICIAL INTEREST HEREIN, THE ACQUIRER: 

(1)         REPRESENTS THAT IT AND ANY ACCOUNT FOR WHICH IT IS ACTING IS A
“QUALIFIED INSTITUTIONAL BUYER” (WITHIN THE MEANING OF RULE 144A UNDER THE SECURITIES ACT) AND THAT IT EXERCISES SOLE INVESTMENT DISCRETION WITH RESPECT TO EACH SUCH ACCOUNT; AND 

(2)         AGREES FOR THE BENEFIT OF THE ISSUER THAT IT WILL NOT OFFER, SELL, PLEDGE
OR OTHERWISE TRANSFER THIS SECURITY OR ANY BENEFICIAL INTEREST HEREIN PRIOR TO RESALE RESTRICTION TERMINATION DATE, EXCEPT: 

(B)         TO HORIZON PHARMA INVESTMENT LIMITED (THE “ISSUER”), HORIZON
PHARMA PUBLIC LIMITED COMPANY (THE “GUARANTOR”) OR ANY OF THEIR RESPECTIVE SUBSIDIARIES, OR 
 (C)
        PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE SECURITIES ACT, OR 

(D)         TO A QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE
SECURITIES ACT, OR 
 (E)         PURSUANT TO AN EXEMPTION FROM REGISTRATION
PROVIDED BY RULE 144 UNDER THE SECURITIES ACT OR ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

PRIOR TO THE REGISTRATION OF ANY TRANSFER IN ACCORDANCE WITH CLAUSE (2)(D) ABOVE, THE GUARANTOR, THE ISSUER OF THE NOTES AND THE
DEPOSITARY FOR THE ISSUER’S ORDINARY SHARES RESERVE THE RIGHT TO REQUIRE THE DELIVERY OF SUCH LEGAL OPINIONS, CERTIFICATIONS OR OTHER EVIDENCE AS MAY REASONABLY BE REQUIRED IN ORDER TO DETERMINE THAT THE PROPOSED TRANSFER IS BEING MADE


  
 A-1 








 
IN COMPLIANCE WITH THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS. NO REPRESENTATION IS MADE AS TO THE AVAILABILITY OF ANY EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES
ACT. 
 THE “RESALE RESTRICTION TERMINATION DATE” MEANS THE DATE THAT IS THE LATER OF: (X) ONE YEAR AFTER THE LAST
ORIGINAL ISSUE DATE OF THE GUARANTOR’S SUBSIDIARY’S 2.50% EXCHANGEABLE SENIOR NOTES DUE 2022 (THE “NOTES”) (INCLUDING THE LAST DATE OF ISSUANCE OF ADDITIONAL NOTES PURSUANT TO THE EXERCISE OF THE INITIAL PURCHASERS’ OPTION
TO PURCHASE ADDITIONAL NOTES) OR SUCH SHORTER PERIOD OF TIME AS PERMITTED BY RULE 144 UNDER THE SECURITIES ACT OR ANY SUCCESSOR PROVISION THERETO AND (Y) SUCH LATER DATE, IF ANY, AS MAY BE REQUIRED BY APPLICABLE LAW. 

  
 A-2 








 EXHIBIT B 

[FORM OF NOTICE OF TAX REDEMPTION ELECTION] 
 To:
     [            ] 
 The undersigned registered owner
of this Note hereby elects to not have this Note, or the portion hereof (that is $200,000 principal amount or an integral multiple of $1,000 in excess thereof) below designated, be subject to a Tax Redemption, and any Notes representing any
principal amount hereof not subject to such Tax Redemption, be issued and delivered to the registered holder hereof unless a different name has been indicated below. If any portion of this Note not subject to such Tax Redemption is to be issued in
the name of a Person other than the undersigned, the undersigned will pay all transfer taxes payable with respect thereto. 
 The
undersigned hereby certifies that it (or if it is acting for the account of one or more persons, that each such person) is not, and has not been, during the ninety days immediately preceding the date hereof, an “affiliate” of the Issuer or
of the Guarantor (within the meaning of Rule 144 under the Securities Act of 1933, as amended). 
  

							
	Dated:		  
				  

				
							  

							  
 Signature(s)

			
	  
				
	  
 Signature Guarantee
				
			
	Signature(s) must be guaranteed by an eligible Guarantor Institution (banks, stock brokers, savings and loan associations and credit unions) with membership in an approved signature guarantee medallion program pursuant
to Securities and Exchange Commission Rule 17Ad-15 if Ordinary Shares are to be issued, or Notes to be delivered, other than to and in the name of the registered holder.				


  
 B-1 









					
	Fill in for registration of Notes to be delivered, other than to and in the name of the registered holder:				
			
	  
				
	  
 (Name)
				
			
	  
				
	  
 (Street Address)
				
			
	  
				
	  
 (City, State and Zip Code)
				
	  
 Please print name and address
				
					Principal amount not subject to Tax Redemption (if less than all):
			
					$                     ,000
			
					NOTICE: The above signature(s) of the holder(s) hereof must correspond with the name as written upon the face of the Note in every particular without alteration or enlargement or any change whatever.
			
					  

					  
 Social Security or Other Taxpayer Identification Number



  
 B-2