Index to Evidence Tables

Comparison indexa 	Secondaryb	Target arm	Comparator arm

M.04.04		16-epiestriol-3-allyl ether (oral)	Placebo (oral)

A.01.01		Acidic syndet bar (topical)	Soap (topical)

E.01.01		Adapalene (0.03%) (topical)	Adapalene (0.1%) (topical)

E.01.02		Adapalene (topical)	Tretinoin (topical)

K.01.01	K.02.04	Alitretinoin (oral)	Isotretinoin(oral)

B.07.02		Aluminum chlorhydroxide/sulphur (topical)	Vehicle (topical)

B.07.03	N.02.06	Aluminum chlorhydroxide/sulphur (topical)	Neomycin/methylprednisolone (topical)

B.07.01		Aluminum chloride (topical)	Vehicle (topical)

A.01.015 		Aluminum oxide (topical)	Other cleansers (topical)

N.01.01		Ayurvedic remedies (oral)	Placebo (oral)

B.01.01		Azelaic acid (topical)	Vehicle (topical)

B.01.02		Azelaic acid (topical)	Benzoyl peroxide (topical)

B.01.03	E.05.04	Azelaic acid (topical)	Tretinoin (topical)

B.01.04	H.08.07	Azelaic acid (topical)	Tetracycline (oral)

B.02.01	E.05.04	Azelaic acid/glycolic acid (topical)	Tretinoin (topical)

D.01.01		Benzoyl peroxide (topical)	Vehicle (topical)

D.01.02	B.01.02	Benzoyl peroxide (topical)	Azelaic acid (topical)

D.01.03		Benzoyl peroxide (topical)	Gluconolactone (topical)

D.01.04		Benzoyl peroxide (topical)	Salicylic acid (topical)

D.01.05		Benzoyl peroxide (topical)	Sulphur/resorcinol (topical)

D.01.06	C.01.06	Benzoyl peroxide (topical)	Clindamycin phosphate (topical)

D.01.07	C.05.01	Benzoyl peroxide (topical)	Meclocycline (topical)

D.01.08	C.08.03	Benzoyl peroxide (topical)	Tetracycline (topical)

D.01.09		Benzoyl peroxide (topical)	Benzoyl peroxide (topical)

D.01.10		Benzoyl peroxide (topical)	Benzoyl peroxide/urea (topical)

D.01.11	D.06.01	Benzoyl peroxide (topical)	Meclocycline/benzoyl peroxide (topical)

D.01.12	D.07.02	Benzoyl peroxide (topical)	Metronidazole/benzoyl peroxide (topical)

D.01.13	E.05.02	Benzoyl peroxide (topical)	Tretinoin (topical)

D.01.14	E.06.02	Benzoyl peroxide (topical)	Vitamin A (topical)

D.01.15	H.06.02	Benzoyl peroxide (topical)	Oxytetracycline (oral)

D.01.16	E.02.02	Benzoyl peroxide (topical)	Isotretinoin (oral)

D.01.17	D.08.01	Benzoyl peroxide (topical)	Miconazole/benoyl peroxide (topical)

D.01.18	N.04.05	Benzoyl peroxide (topical)	Chloramphenicol/hydrocortisone/sulfur (topical)

D.01.19	N.01.03	Benzoyl peroxide (topical)	Isolutrol (topical)

D.03.02		Benzoyl

peroxide/chlorhydroxyquinolone/hydrocortison

e

(topical)	Benzoyl peroxide/hydroxyquinolone (topical)

D.03.03		Benzoyl

peroxide/chlorhydroxyquinolone/hydrocortison

e

(topical)	Benzoyl peroxide/chlorhydroxyquinolone (topical)

D.03.01		Benzoyl peroxide/glycolic acid/zinc sulphur

(topical)	Placebo (topical)

D.03.04		Benzoyl peroxide/sulphur (topical)	Sulphur (topical)

D.02.01	N.04.03	Chloramphenical/sulpur (topical)	Chloramphenical/hydrocortisone/sulpur (topical)

N.04.01		Chloramphenicol/hydrocortisone	Vehicle (topical)

N.04.06	E.05.09	Chloramphenicol/hydrocortisone (topical)	Tretinoin (topical)

N.04.03		Chloramphenicol/hydrocortisone/sulphur

(topical)	Chloramphenicol/sulphur (topical)

N.04.04		Chloramphenicol/hydrocortisone/sulphur

(topical)	Hydrocortisone/sulphur (topical)

N.04.05		Chloramphenicol/hydrocortisone/sulphur

(topical)	Benzoyl peroxide (topical)

N.06.01		Cimetidine [men] (oral)	Cimetidine [women] (oral)

H.01.01		Clindamycin (oral)	Placebo (oral)

H.01.02		Clindamycin (oral)	Tetracycline (oral)

C.01.01		Clindamycin (topical)	Vehicle (topical)

C.01.02		Clindamycin (topical)	Nicotinamide (topical)

C.01.03		Clindamycin (topical)	Clindamycin (topical)

C.01.04		Clindamycin (topical)	Erythromycin (topical)

C.01.05		Clindamycin (topical)	Tetracycline (topical)

C.01.07		Clindamycin (topical)	Clindamycin/benzoyl peroxide (topical)

C.01.08	D.05.02	Clindamycin (topical)	Erythromycin/benzoyl peroxide (topical)

C.01.09	N.08.03	Clindamycin (topical)	Erythromycin/zinc (topical)

C.01.06		Clindamycin phosphate (topical)	Benzoyl peroxide (topical)

C.02.01		Clindamycin/benzoyl peroxide (topical)	Vehicle (topical)

C.02.02	C.01.07	Clindamycin/benzoyl peroxide (topical)	Clindamycin (topical)

C.02.03		Clindamycin/benzoyl peroxide (topical)	Benzoyl peroxide (topical)

D.04.01		Clindamycin/benzoyl peroxide (topical)	Vehicle (topical)

D.04.02	C.01.07	Clindamycin/benzoyl peroxide (topical)	Clindamycin (topical)

D.04.03	C.02.03	Clindamycin/benzoyl peroxide (topical)	Benzoyl peroxide (topical)

N.02.01		Clobetasol (topical)	Vehicle (topical)

N.05.02		Comedone extraction  (cheeks/forehead)	Untreated

N.06.02		Contingent contract/benzoyl peroxide (topical)	Benzoyl peroxide (topical)

H.07.01		Cotrimoxazole (oral)	Placebo (oral)

I.01.01		Cotrimoxazole (oral)/sulphur/resorcinol

(topical)	Cotrimoxazole (oral)

I.01.02		Cotrimoxazole (oral)/sulphur/resorcinol

(topical)	Cotrimoxazole (oral)/tretinoin

J.01.01		Cotrimoxazole (oral)/Tretinoin (topical)	Cotrimoxazole (oral)

M.01.06		Cyproterone (2 mg)/ethinyl estradiol (oral)	Cyproterone (0.05 mg)/ethinyl estradiol (oral)

M.01.09		Cyproterone (50)/ethinyl estradiol (oral)	Norethisterone/placebo/ethinyl estradiol (oral)

M.01.01		Cyproterone (topical)	Vehicle (topical)

M.01.01		Cyproterone/ethinyl estradiol (0.035) (oral)	Vehicle (topical)

M.01.04		Cyproterone/ethinyl estradiol (0.035) (oral)	Cyproterone (topical)

M.01.07		Cyproterone/ethinyl estradiol (0.035) (oral)	Desogestrel/ethinyl estradiol (oral)

M.01.08		Cyproterone/ethinyl estradiol (0.035) (oral)	Levonorgestrel/ethinyl estradiol (0.030) (oral)

M.01.05		Cyproterone/ethinyl estradiol (0.05) (oral)	Cyproterone/ethinyl estradiol (0.035) (oral)

M.01.02		Cyproterone/ethinyl estradiol (oral)	Minocycline hydrochloride (oral)

M.01.03		Cyproterone/ethinyl estradiol (oral)	Tetracycline (oral)

H.09.01		Dapsone (oral)	Placebo (oral)

M.04.01		Delta-0.2%-chlormadione (oral)	Placebo (oral)

M.04.03		Delta-0.2%-chlormadione (oral)	Delta-5%-chlormadione (oral)

M.04.02		Delta-5%-chlormadione (oral)	Placebo (oral)

H.02.01		Demethylchlortetracycline (oral)	Placebo (oral)

H.02.02		Demethylchlortetracycline (oral)	Phenethicillin (oral)

H.02.03		Demethylchlortetracycline (oral)	Tetracycline (oral)

M.02.01		Desogestrel/ethinyl estradiol (oral)	Gestodene/ethinyl estradiol (oral)

M.02.02		Desogestrel/ethinyl estradiol (oral)	Levonorgestrel/ethinyl estradiol (oral)

H.03.01		Doxycycline (oral)	Placebo (oral)

H.03.02		Doxycycline (oral)	Fusidic acid cream (topical)

H.03.03		Doxycycline (oral)	Erythromycin stearate (oral)

H.03.04		Doxycycline (oral)	Minocycline (oral)

M.04.05		Epiestriol (oral)	Placebo (oral)

H.04.01	H.03.03	Erythromycin (oral)	Doxycycline (oral)

H.04.03		Erythromycin (oral)	Tetracycline (oral)

H.04.04		Erythromycin (oral)	Triacetyl-oleandomycin (oral)

C.03.01		Erythromycin (topical)	Vehicle (topical)

C.03.02	C.01.04	Erythromycin (topical)	Clindamycin (topical)

C.03.025		Erythromycin (topical)	Benzoyl peroxide (topical)

C.03.03	N.08.02	Erythromycin (topical)	Erythromycin/zinc (topical)

H.04.02		Erythromycin base (oral)	Erythromycin stearate (oral)

D.05.01		Erythromycin/benzoyl peroxide (topical)	Placebo (topical)

D.05.015 		Erythromycin/benzoyl peroxide (topical)	Benzoyl peroxide (topical)

D.05.02		Erythromycin/benzoyl peroxide (topical)	Clindamycin phosphate (topical)

D.05.03		Erythromycin/benzoyl peroxide (topical)	Benzoyl peroxide/glycolic acid/zinc sulphur

(topical)

D.05.04		Erythromycin/benzoyl peroxide (topical)	Erythromycin/zinc (topical)

D.05.05	N.06.03	Erythromycin/benzoyl peroxide (topical)	Group therapy

D.05.06	N.06.03	Erythromycin/benzoyl peroxide (topical)	Relaxation training/erythromycin/benzoyl peroxide

(topical)

N.05.03		Fulguration	Tretinoin (topical)

N.05.04		Fulguration	Electrocautery

C.04.01		Fusiden (topical)	Vehicle (topical)

C.04.02	H.03.02	Fusidic acid (topical)	Doxycycline (oral)

C.04.03	H.09.05	Fusidic acid (topical)	Sodium fusidate (oral)

N.03.01		Gamma-globulin (parenteral)	Placebo (parenteral)

B.07.04		Gluconolactone (topical)	Vehicle (topical)

B.07.05	D.01.03	Gluconolactone (topical)	Benzoyl peroxide (topical)

B.07.06		Glycolic acid/soybean liposome (topical)	Soybean liposome (topical)

N.05.01		Grenz rays	Sham rays

N.01.02		Gugulipid (oral)	Tetracycline (oral)

A.01.02	C.09.02	Hexachlorophene (topical)	Triclosan (topical)

N.06.04		Hydrochlorthiazide (oral)	Placebo (oral)

N.02.03		Hydrocortisone (topical)	Hydrocortisone/sulfur (topical)

N.04.02		Hydrocortisone/buttoxethyl

nicotinate/chloramphenicol	Vehicle (topical)

N.02.02		Hydrocortisone/neomycin/sulfur/resorcinol

(topical)	Components (topical)

N.06.045 		Ibuprofen/tetracycline (oral)	Placebo (oral)

M.04.06		Inocoterone acetate (oral)	Placebo (oral)

N.01.03		Isolutrol (topical)	Benzoyl peroxide (topical)

E.02.03		Isotretinoin (0.05% topical)	Isotretinoin (0.1% topical)

K.02.01		Isotretinoin (oral)	Placebo (oral)

K.02.02		Isotretinoin (oral)	Dapsone (oral)

K.02.03		Isotretinoin (oral)	Tetracycline HCl (oral)

K.02.04		Isotretinoin (oral)	Altretinoin (oral)

K.02.05		Isotretinoin (oral)	Etretinate (oral)

K.02.06		Isotretinoin (oral)	Isotretinoin (oral)

E.02.01		Isotretinoin (topical)	Vehicle (topical)

E.02.02		Isotretinoin (topical)	Benzoyl peroxide (topical)

E.02.04		Isotretinoin (topical)	Tretinoin (topical)

B.06.01		Komed (sulphur/salicylic acid/resorcinol)

(topical)	Placebo (topical)

B.06.02		Komed (sulphur/salicylic acid/resorcinol)

(topical)	Proprietary formula (sulphur/salicylic

acid/resorcinol)

M.04.07	M.01.08	Levonorgestrel/ethinyl estradiol (oral)	Cyproterone/ethinyl estradiol (oral)

C.05.01		Meclocycline (topical)	Benzoyl peroxide (topical)

C.05.02	H.08.06	Meclocycline (topical)	Tetracycline (oral)

C.05.005 		Meclocycline (topical)	Inert (topical)

D.06.01		Meclocycline/benzoyl peroxide (topical)	Benzoyl peroxide (topical)

N.02.04		Methylprednisolone/neomycin (topical)	Vehicle (topical)

N.02.06		Methylprednisolone/neomycin (topical)	Aluminum chlorhydroxide/sulphur (topical)

N.02.07	E.05.08	Methylprednisolone/neomycin (topical)	Tretinoin (topical)

N.02.05		Methylprednisolone/neomycin/sulphur

(topical)	Vehicle (topical)

C.06.01		Metronidazole (topical)	Placebo (topical)

D.07.01		Metronidazole/benzoyl peroxide (topical)	Vehicle (topical)

D.07.02		Metronidazole/benzoyl peroxide (topical)	Benzoyl peroxide (topical)

D.07.03	H.06.03	Metronidazole/benzoyl peroxide (topical)	Oxytetracycline (oral)

D.08.01		Miconazole/benzoyl peroxide (topical)	Benzoyl peroxide (topical)

D.0802		Miconazole/benzoyl peroxide (topical)	Isoconazole/benzoyl peroxide (topical)

H.05.01		Minocycline (oral)	Placebo (oral)

H.05.02		Minocycline (oral)	Clindamycin phosphate (topical)

H.05.03	H.03.04	Minocycline (oral)	Doxycycline (oral)

H.05.04		Minocycline (oral)	Tetracycline (oral)

E.03.02		Motretinide (bid) (topical)	Motretinide (qd) (topical)

E.03.01		Motretinide (topical)	Vehicle (topical)

E.03.03		Motretinide (topical)	Tretinoin (topical)

C.07.01		Neomycin (topical)	Keratolytics/anti-inflammatory (topical)

B.07.07	C.01.02	Nicotinamide (topical)	Clindamycin (topical)

M.04.08	M.01.09	Norethisterone/placebo/ethinyl estradiol (oral)	Cyproterone cyproterone/ethinyl estradiol (oral)

M.04.09		Norgestimate/ethinyl estradiol (oral)	Placebo (oral)

N.01.04		Ocimum basilicum  (topical)	Tetracycline (oral)

H.04.06		Oleandomycin (oral)	Triacetyl-oleandomycin (oral)

H.06.01		Oxytetracycline (oral)	Placebo (oral)

H.06.02		Oxytetracycline (oral)	Benzoyl peroxide (topical)

H.06.03		Oxytetracycline (oral)	Benzoyl peroxide/metronidazole (topical)

H.06.04	E.06.03	Oxytetracycline (oral)	Vitamin A (topical)

H.06.05		Oxytetracycline (oral)	Tetracycline (topical)

H.06.05		Oxytetracycline (oral)	Cotrimoxazole (oral)

H.06.06		Oxytetracycline (oral)	Cotrimoxazole (oral)

H.06.07		Oxytetracycline (oral)	Trimethoprim (oral)

J.01.02		Oxytetracycline (oral)/vitamin A (topical)	Oxytetracycline (oral)

H.09.02		Phenethicillin (oral)	Placebo (oral)

H.09.03	H.02.02	Phenethicillin (oral)	Demethylchlortetracycline (oral)

A.01.03	E.05.01	Polyprepolymer-2 (topical)	Tretinoin (topical)

B.05.01		Polythionate/quaternary ammonia complex of

polythionate (topical)	Polythionate (topical)

A.01.04		Povidone-iodine (topical)	Vehicle (topical)

M.04.10		Quinestradol (oral)	Placebo (oral)

N.06.03		Relaxation training/erythromycin/benzoyl

peroxide (topical)	Erythromycin/benzoyl peroxide (topical)

E.04.01		Retinyl beta-glucuronide (topical)	Vehicle (topical)

E.04.02		Retinyl beta-glucuronide (topical)	Tretinoin (topical)

H.04.05		Roxithromycin (150 mg) (oral)	Roxithromycin (300 mg) (oral)

B.03.01		Salicylic acid (topical)	Placebo (topical)

B.03.02	D.01.04	Salicylic acid (topical)	Benzoyl peroxide (topical)

M.04.11		Serum gonadotrophin (oral)	Placebo (oral)

A.01.05		Silicic acid (topical)	Vehicle (topical)

H.09.04		Sodium fusidate (oral)	Sodium fusidate (topical)

M.03.01		Spironolactone (oral)	Placebo (oral)

N.03.03		Staphylococcal toxoid (topical)	Vehicle (topical)

H.07.02		Sulfadimethoxine (oral)	Placebo (oral)

B.04.01	D.01.05	Sulphur/resorcinol (topical)	Benzoyl peroxide (topical)

B.04.02	E.06.02	Sulphur/resorcinol (topical)	Vitamin A (topical)

B.05.02		Sulphurated lime (topical)	Vehicle (topical)

N.01.05		Tea tree oil (topical)	Benzoyl peroxide (topical)

H.08.01		Tetracycline (oral)	Placebo (oral)

H.08.02		Tetracycline (oral)	Clindamycin (topical)

H.08.03		Tetracycline (oral)	Erythromycin (topical)

H.08.04		Tetracycline (oral)	Tetracycline (topical)

H.08.05		Tetracycline (oral)	Azelaic acid  (topical)

H.08.06		Tetracycline (oral)	Meclocycline sulfosalicylate  (topical)

H.08.07	H.01.02	Tetracycline (oral)	Clindamycin (oral)

H.08.08		Tetracycline (oral)	Tetracycline (oral)

H.08.09	K.02.03	Tetracycline (oral)	Isotretinoin (oral)

H.08.10		Tetracycline (oral)	Cyproterone/ethinyl estradiol (oral)

H.08.11	N.01.02	Tetracycline (oral)	Guglipid (oral)

H.08.12	N.01.04	Tetracycline (oral)	Ocimum basilicum (oral)

H.08.13	N.07.03	Tetracycline (oral)	Zinc (oral)

H.08.14		Tetracycline (oral)/povidone-iodine	Tetracycline (oral)

I.02.01		Tetracycline (oral)/sulphur/salicylic

acid/polyethylene scrub	Tretinoin/benzoyl peroxide/water avoidance

(topical)

J.01.03		Tetracycline (oral)/tretinoin/emollient  (topical)	Tetracycline (oral)/sulphur/salicylic

acid/polyethylene scrub (topical)

C.08.01		Tetracycline (topical)	Vehicle (topical)

C.08.02	C.01.05	Tetracycline (topical)	Clindamycin (topical)

C.08.03		Tetracycline (topical)	Benzoyl peroxide (topical)

C.08.04	H.08.14	Tetracycline (topical)	Povidone-iodine/tetracycline (topical)

C.08.05	H.06.05	Tetracycline (topical)	Oxytetracycline (oral)

C.08.06	H.08.05	Tetracycline (topical)	Tetracycline (oral)

H.09.05		Tetracycline/novobiocin (oral)	Placebo (oral)

H.08.085 		Tetracycline/sodium novobiocin (oral)	Placebo (oral)

N.06.05		Tolbutamide (oral)	Placebo (oral)

E.05.01		Tretinoin (topical)	Vehicle (topical)

E.05.015 		Tretinoin (topical)	Salicylic acid/resorcinol/sulphur (topical)

E.05.02		Tretinoin (topical)	Benzoyl peroxide (topical)

E.05.03	E.03.03	Tretinoin (topical)	Motretinide (topical)

E.05.04		Tretinoin (topical)	Azelaic acid (topical)

E.05.05	E.02.04	Tretinoin (topical)	Isotretinoin (topical)

E.05.06	E.04.02	Tretinoin (topical)	Retinyl beta-glucuronide (topical)

E.05.07		Tretinoin (topical)	Tretinoin (topical)

E.05.08		Tretinoin (topical)	Methylprednisolone/neomycin (topical)

E.05.09		Tretinoin (topical)	Chloramphenical/hydrocortisone (topical)

G.02.01		Tretinoin/clindamycin (topical)	Clindamycin (topical)

G.02.02 		Tretinoin/clindamycin (topical)	Tretinoin (topical)

G.02.03 		Tretinoin/clindamycin (topical)	Tetracycline (topical)

G.01.01		Tretinoin/erythromycin (topical)	Vehicle (topical)

C.09.01		Triclosan (topical)	Vehicle (topical)

C.09.02		Triclosan (topical)	Hexachlorophene  (topical)

C.09.03		Triclosan/propylene phenoxetol (topical)	Vehicle (topical)

N.03.02		Unfractionated dialyzable transfer factor

(topical)	Fractionated dialyzable transfer factor (topical)

K.03.01		Vitamin A (oral)	Placebo (oral)

K.03.02		Vitamin A (oral)	Zinc Sulfate (oral)

E.06.01		Vitamin A (topical)	Vehicle (topical)

E.06.02		Vitamin A (topical)	Keratolytics (topical)

E.06.03		Vitamin A (topical)	Oxytetracycline (oral)

N.07.01		Zinc (topical)	Vehicle (topical)

N.07.02		Zinc sulphate (oral)	Placebo (oral)

N.07.03		Zinc sulphate/citrate complex (oral)	Tetracycline (oral)

N.08.01		Zinc/erythromycin (topical)	Vehicle (topical)

N.08.02		Zinc/erythromycin (topical)	Erythromycin (topical)

N.08.03		Zinc/erythromycin (topical)	Clindamycin phosphate (topical)

Evidence Tables