Evidence Report/Technology Assessment

Number 17

Management of Acne

Volume 2:  Evidence Tables and Bibliography

Prepared  for:

Agency for Healthcare Research and Quality

Department of Health and Human Services

U.S. Public Health Service

2101 East Jefferson Street

Rockville, MD 20852

www.ahrq.gov

Contract No. 290-97-006

Prepared  by:

Johns Hopkins Evidence-based Practice Center

Harold P. Lehmann, M.D., Ph.D.

Principal Investigator

John S. Andrews, M.D.

Co-Principal Investigator

Karen A. Robinson, M.Sc.

Victoria L. Holloway, M.D., M.P.H.

Steven N. Goodman, M.D., Ph.D.

Investigators

AHRQ Publication No. 01-E019

September 2001

ISBN 1-58763-059-1

ISSN 1530-4396

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Contents: Volume 2

												    Page

Description of the Evidence Tables	1

	Summary Information	1

	Presentation of Two- and Three-Arm vs. Multi-Arm Trials	2

		Two- and Three-Arm Trials	3

		Trials With More Than Three Arms	5

Index to Evidence Tables	6

Evidence Tables

Summary Table.  Trials included in the article review	18

A.1.  Articles/arms for class Cleanser (topical)	86

A.2.  Continuous outcomes for class Cleanser (topical)	87

A.3.  Discrete outcomes for class Cleanser (topical)	88

B.1.  Articles/arms for class Keratolytic (topical)	89

B.2.  Continuous outcomes for class Keratolytic (topical)	91

B.3.  Discrete outcomes for class Keratolytic (topical)	95

C.1.  Articles/arms for class Anti-bacterial (topical)	98

C.2.  Continuous outcomes for class Anti-bacterial  (topical)	103

C.3.  Discrete outcomes for class Anti-bacterial (topical)	124

D.1.  Articles/arms for class Anti-bacterial (topical)/Keratolytic (topical)	131

D.2.  Continuous outcomes for class Anti-bacterial (topical)/Keratolytic (topical)	135

D.3.  Discrete outcomes for class Anti-bacterial (topical)/Keratolytic (topical)	142

E.1.  Articles/arms for class Retinoid (topical)	146

E.2.  Continuous outcomes for class Retinoid (topical)	151

E.3.  Discrete outcomes for class Retinoid (topical)	169

G.1.  Articles/arms for class Anti-bacterial/Retinoid (topical)	184

G.2.  Continuous outcomes for class Anti-bacterial/Retinoid (topical)	185

H.1.  Articles/arms for class Anti-bacterial (oral)	187

H.2.  Continuous outcomes for class Anti-bacterial (oral)	194

H.3.  Discrete outcomes for class Anti-bacterial (oral)	209

I.1.   Articles/arms for class Anti-bacterial (oral)/Keratolytic (topical)	223

I.2.   Continuous outcomes for class Anti-bacterial (oral)/Keratolytic (topical)	224

J.1.   Articles/arms for class Anti-bacterial (oral)/Retinoid (topical)	226

J.2.   Continuous outcomes for class Anti-bacterial (oral)/Retinoid (topical)		227

J.3.   Discrete outcomes for class Anti-bacterial (oral)/Retinoid (topical)	229

K.1.  Articles/arms for class Retinoid (oral)	230

K.2.  Continuous outcomes for class Retinoid (oral)	232

K.3.  Discrete outcomes for class Retinoid (oral)	239	

M.1. Articles/arms for class Anti-androgen	241

M.2. Continuous outcomes for class Anti-androgen	245

M.3. Discrete outcomes for class Anti-androgen	252

N.1.  Articles/arms for class Other	259

N.2.  Continuous outcomes for class Other	265

N.3.  Discrete outcomes for class Other	275

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Multi.1. Trials with multi-arm outcomes	285

Multi.2. Continuous outcomes of  multi-arm trials	 287

Multi.3. Discrete outcomes of  multi-arm trials	297

Bibliography	

Selected Clinical Abbreviations Used in the Evidence Tables	308

Bibliography	309

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