Registration Notice Conditional v.20150320

U.S. ENVIRONMENTAL PROTECTION AGENCY

Office of Pesticide Programs

Registration Division (7505P)

1200 Pennsylvania Ave., N.W.

Washington, D.C. 20460

EPA Reg. Number:

100-1476

Date of Issuance:

8/28/2015

NOTICE OF PESTICIDE: 

 X Registration

 Reregistration

Term of Issuance: 

Conditional

 

(under FIFRA, as amended)

Name of Pesticide Product:

Aprovia Top Fungicide

Name and Address of Registrant (include ZIP Code):

Adora Clark

Syngenta Crop Protection, LLC

P.O. Box 18300

410 Swing Road

Greensboro, NC 27419

Note: Changes in labeling differing in substance from that accepted in connection with this registration must be submitted to and accepted by the 

Registration Division prior to use of the label in commerce. In any correspondence on this product always refer to the above EPA registration number.

On the basis of information furnished by the registrant, the above named pesticide is hereby registered 

under the Federal Insecticide, Fungicide and Rodenticide Act.

Registration is in no way to be construed as an endorsement or recommendation of this product by the 

Agency. In order to protect health and the environment, the Administrator, on his motion, may at any 

time suspend or cancel the registration of a pesticide in accordance with the Act. The acceptance of any 

name in connection with the registration of a product under this Act is not to be construed as giving the 

registrant a right to exclusive use of the name or to its use if it has been covered by others.

This product is conditionally registered in accordance with FIFRA section 3(c)(7)(C). You must comply 

with the following conditions:

1. Submit and/or cite all data required for registration/reregistration/registration review of your 

product under FIFRA when the Agency requires all registrants of similar products to submit such 

data. 

Signature of Approving Official:

(for) Cynthia Giles-Parker, Chief

Fungicide Branch

Registration Division 7505P

Date:

 08/28/2015

EPA Form 8570-6
Page 2 of 4

EPA Reg. No. 100-1476 

Decision No. 473379

2. You are required to submit to the Agency the following studies by the dates indicated below.

a.Acute oral toxicity to larval honey bees.

b. Chronic oral toxicity to larval honey bees.

c. Chronic oral toxicity to adult honey bees.

Protocols for both of the chronic bee studies must be submitted within 60 days of the 

registration. The deadline for you to submit each of the bee studies is 09/01/18. 

Tier II studies are required if triggered by the Tier I studies listed above. In the event Tier III 

studies are triggered by the Tier II results, they will also be required. If any higher tier 

studies are necessary, you must submit them to EPA within 3 years of notification by the 

agency that such higher tier studies are required. 

d. A controlled water monitoring study to provide further data on the environmental fate of

benzovindiflupyr in the aquatic environment must be submitted to the Agency. A protocol 

must be submitted within 90 days of the registration. A preliminary report must be submitted 

by 12/31/16. An updated report must be submitted by 12/31/17. The completed study must 

be submitted by 09/01/18. If the EPA does not respond to the submitted protocol within 

sixty (60) days of receipt, EPA and the Registrant will discuss and agree to reasonable 

extensions of the dates for submission of the preliminary report and study. 

e. Field study to determine the effectiveness of vegetative filter strips (VFS). The study should

address effectiveness relative to run-off reduction, sediment transport rates and delivery

totals of benzovindiflupyr in water bodies. A protocol must be submitted within 90 days of

the registration. A preliminary report must be submitted by 12/31/16. The deadline for you to

submit the study is 09/01/18. If the EPA does not respond to the submitted protocol within

sixty (60) days of receipt, EPA and the Registrant will discuss and agree to reasonable

extensions of the dates for submission of the preliminary report and study.

f. Based on the EPA’s review of the results of the studies in pagragraphs d. and e., EPA may

determine either that the study described in paragraph d. must be extended or that other

studies or monitoring are needed in order to allow the Agency to continue to conclude that

benzovindiflupyr does not pose unreasonable adverse effects on the environment insofar as

aquatic risk are concerned as per the agreement letter of August 28, 2015.

g.In addition to the VFS study, the registrant within one hundred and twenty (120) days of

registration must submit plans for an educational program on VFS. The program will start in

2015. It will include educational resources on best practices for construction and

maintenance of filter strips and information on the effectiveness of vegetative filter strips as

related to their size. The educational resources will be focused on use by landowners and

those leasing land. The resources may be generic (not chemical or product-specific) and will

be developed in collaboration with partners in the Extension, University, State Lead Agency,

and other education communities to meet State and local needs. Copies of all educational

materials must be submitted to the Agency. Additionally, status reports on the materials’
Page 3 of 4

EPA Reg. No. 100-1476 

Decision No. 473379

creation, distribution efforts, and any public feedback resulting from trainings/dissemination 

of the materials are required. 

h. An additional chronic (42-d) sediment toxicity study with the freshwater amphipod, Hyalella

azteca. A protocol must be submitted within ninety (90) days of the issuance of the

registration. The deadline for the study is 09/01/17.

If the EPA determines, based on the data submitted pursuant to the conditions in the Notice or on any 

other data or other information received by the Agency, that one or more label revisions are required to 

prevent unreasonable adverse effects on the environment insofar as aquatic risks are concerned, EPA 

may notify the Registrant of the Agency’s determination that identified revisions to the label are 

necessary as per the agreement letter from the Registrant dated August 28, 2015. If labels revisions are 

necessary to mitigate adverse effects, you must incorporate all revisions identified by the Agency and 

submit for approval a revised label within sixty (60) days of the Agency’s notification to you of the need 

for such a revised label. In the event of such a revision, product may not be released for shipment under 

the terms of this registration more than twelve (12) months after the Agency approves such a revised 

label unless the product bears the appropriate revised label. 

3. Make the following label changes before you release the product for shipment:

 Revise the EPA Registration Number to read, “EPA Reg. No. 100-1476.”

4. Submit one copy of the final printed label for the record before you release the product for

shipment.

Should you wish to add/retain a reference to the company’s website on your label, then please be aware 

that with such a reference, the website becomes labeling under the Federal Insecticide Fungicide and 

Rodenticide Act and is subject to review by the Agency. If the website is false or misleading, the 

product would be misbranded and unlawful to sell or distribute under FIFRA section 12(a)(1)(E). 40 

CFR 156.10(a)(5) list examples of statements EPA may consider false or misleading. In addition, 

regardless of whether a website is referenced on your product’s label, claims made on the website may 

not substantially differ from those claims approved through the registration process. Therefore, should 

the Agency find or if it is brought to our attention that a website contains false or misleading statements 

or claims substantially differing from the EPA approved registration, the website will be referred to the 

EPA’s Office of Enforcement and Compliance.

If you fail to satisfy these data requirements, EPA will consider appropriate regulatory action including, 

among other things, cancellation under FIFRA section 6(e). Your release for shipment of the product 

constitutes acceptance of these conditions. 

A stamped copy of the label is enclosed for your records. Please also note that the record for this 

product currently contains the following CSFs: 
Page 4 of 4

EPA Reg. No. 100-1476

Decision No. 473379

 Basic CSF dated 11/09/2012

 Alternate CSF 1 dated 11/09/2012

If you have any questions, please contact Shaunta Hill by phone at 703-347-8961, or via email at 

hill.shaunta@epa.gov.
Aprovia Top Fungicide 

Page 1 

GROUP 11 3 FUNGICIDES

AproviaTM Top Fungicide 

Active Ingredients:

Difenoconazole* .................................................................................................... 11.25% 

Benzovindiflupyr** ..................................................................................................... 7.5% 

Other Ingredients: 81.25% 

Total: 100.0% 

 *CAS No. 119446-68-3 

**CAS No. 1072957-71-1 

Contains 0.97 lb ai of difenoconazole active ingredient and 0.65 lb ai of benzovindiflupyr 

active ingredient per gallon. 

KEEP OUT OF REACH OF CHILDREN. 

DANGER/PELIGRO 

Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en 

detalle. (If you do not understand the label, find someone to explain it to you in detail.) 

See additional precautionary statements and directions for use inside booklet. 

EPA Reg. No. 

EPA Est. 

Product of 

SCP 

Net Contents ______________ 

08/28/2015

100-1476
Aprovia Top Fungicide 

Page 2 

FIRST AID 

If in eyes x Hold eye open and rinse slowly and gently with water for 15-20 

minutes. 

x Remove contact lenses, if present, after the first 5 minutes, then 

continue rinsing eye. 

x Call a poison control center or doctor for treatment advice. 

If inhaled x Move person to fresh air. 

x If person is not breathing, call 911 or an ambulance, then give 

artificial respiration, preferably by mouth-to-mouth, if possible. 

x Call a poison control center or doctor for further treatment 

advice. 

If swallowed x Call a poison control center or doctor immediately for treatment 

advice. 

x Have person sip a glass of water if able to swallow. 

x Do not induce vomiting unless told to by a poison control center 

or doctor. 

x Do not give anything by mouth to an unconscious person.

If on skin or 

clothing

x Take off contaminated clothing. 

x Rinse skin immediately with plenty of water for 15-20 minutes. 

x Call a poison control center or doctor for treatment advice.

Have the product container or label with you when calling a poison control center or 

doctor, or going for treatment.

NOTE TO PHYSICIAN 

Probable mucosal damage may contraindicate the use of gastric lavage. 

HOT LINE NUMBER 

For 24-Hour Medical Emergency Assistance (Human or Animal) 

Or Chemical Emergency Assistance (Spill, Leak, Fire or Accident) 

Call 

1-800-888-8372

PRECAUTIONARY STATEMENTS 

Hazards to Humans and Domestic Animals 

DANGER 

Corrosive to the eye. Causes irreversible eye damage. Harmful if swallowed or 

inhaled. Do not get in eyes or on clothing. Avoid breathing spray mist. Avoid contact 

with skin, eyes, or clothing. 
Aprovia Top Fungicide 

Page 3 

Personal Protective Equipment (PPE) 

Applicators and other handlers must wear: 

x Long-sleeved shirt and long pants

x Shoes plus socks

x Protective eyewear (goggles, face shield, or safety glasses)

x Chemical-resistant gloves such as barrier laminate, butyl rubber, nitrile rubber,

neoprene rubber, natural rubber, polyethylene, polyvinyl chloride (PVC) or Viton®.

User Safety Requirements 

Discard clothing and other absorbed materials that have been drenched or heavily 

contaminated with this product’s concentrate. Follow manufacturer’s instructions for 

cleaning/maintaining PPE. If no such instructions for washables exist, use detergent 

and hot water. Keep and wash PPE separately from other laundry. 

Engineering Control Statement 

When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets 

the requirements listed in the Worker Protection Standard (WPS) for agricultural 

pesticides [40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or 

modified as specified in the WPS. 

User Safety Recommendations 

Users should: 

x Wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet.

x Remove clothing/PPE immediately if pesticide gets inside. Then wash thoroughly

and put on clean clothing.

x Remove PPE immediately after handling this product. Wash the outside of gloves

before removing. As soon as possible, wash thoroughly and change into clean

clothing.

Environmental Hazards 

Benzovindiflupyr and difenoconazole are toxic to fish, aquatic invertebrates and 

mammals. Drift and runoff may be hazardous to aquatic organisms in water adjacent to 

treated area. For terrestrial uses: Do not apply directly to water, or to areas here 

surface water is present, or to intertidal areas below the mean high water mark. Do not 

contaminate water when disposing of equipment washwater or rinsate. 
Aprovia Top Fungicide 

Page 4 

Physical RUChemical HazardV

Do not mix or allow coming in contact with oxidizing agent. Hazardous chemical 

reactions may occur. 

Surface Water Advisory 

This product may impact surface water quality due to runoff of rain water. This is 

especially true for poorly draining soils and soils with shallow ground water. A 15-foot 

vegetative buffer strip between areas to which this product is applied and surface water 

features such as ponds, streams, and springs will reduce the potential loading of 

benzovindiflupyr from runoff water and sediment. Do not cultivate within 15 feet of the 

aquatic areas to allow growth of a vegetative filter strip. Runoff of this product will be 

reduced by avoiding applications when rainfall or irrigation is expected to occur within 

48 hours. Sound erosion control practices will reduce this product’s potential to reach 

aquatic sediment via runoff. 
Aprovia Top Fungicide 

Page 5 

CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 

NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 

Warranty and Liability before buying or using this product. If the terms are not 

acceptable, return the product at once, unopened, and the purchase price will be 

refunded. 

The Directions for Use of this product must be followed carefully. It is impossible to 

eliminate all risks inherently associated with the use of this product. Crop injury, 

ineffectiveness or other unintended consequences may result because of such factors 

as manner of use or application, weather or crop conditions, presence of other materials 

or other influencing factors in the use of the product, which are beyond the control of 

SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by 

applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any 

claims relating to such factors. 

SYNGENTA warrants that this product conforms to the chemical description on the label 

and is reasonably fit for the purposes stated in the Directions for Use, subject to the 

inherent risks referred to above, when used in accordance with directions under normal 

use conditions. To the extent permitted by applicable law: (1) this warranty does not 

extend to the use of this product contrary to label instructions or under conditions not 

reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and, (2) Buyer 

and User assume the risk of any such use. TO THE EXTENT PERMITTED BY 

APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY 

OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR 

IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. 

To the extent permitted by applicable law, in no event shall SYNGENTA be liable for 

any incidental, consequential or special damages resulting from the use or handling of 

this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE 

EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY 

OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES 

OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 

CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 

RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 

RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 

OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT.

SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 

foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 

modified except by written agreement signed by a duly authorized representative of 

SYNGENTA. 
Aprovia Top Fungicide 

Page 6 

DIRECTIONS FOR USE 

It is a violation of Federal Law to use this product in a manner inconsistent with its 

labeling. 

Do not apply this product in a way that will contact workers or other persons, either 

directly or through drift. Only protected handlers may be in the area during application. 

For any requirements specific to your State or Tribe, consult the agency responsible for 

pesticide regulation. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection 

Standard, 40 CFR Part 170. This Standard contains requirements for the protection of 

agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 

agricultural pesticides. It contains requirements for training, decontamination, 

notification, and emergency assistance. It also contains specific instructions and 

exceptions pertaining to the statements on this label about personal protective 

equipment (PPE) and restricted-entry interval. The requirements in this box only apply 

to uses of this product that are covered by the Worker Protection Standard. 

Do not enter or allow worker entry into treated areas during the restricted-entry 

interval (REI) of 12 hours. 

PPE required for early entry to treated areas that is permitted under the Worker 

Protection Standard and that involves contact with anything that has been treated, such 

as plants, soil, or water is: 

x Coveralls 

x Shoes plus socks 

x Protective eyewear (goggles, face shield, or safety glasses) 

x Chemical-resistant gloves such as barrier laminate, butyl rubber, nitrile rubber, 

neoprene rubber, natural rubber, polyethylene, polyvinyl chloride (PVC) or Viton®

FAILURE TO FOLLOW DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY 

RESULT IN CROP INJURY, POOR DISEASE CONTROL, AND/OR ILLEGAL 

RESIDUES.

PRODUCT INFORMATION 

Aprovia Top Fungicide is a broad-spectrum product containing two fungicides. It has 

preventive and curative properties and is recommended for the control of many 

important plant diseases. Aprovia Top Fungicide provides excellent disease control of 

many leaf spots and powdery mildews. Aprovia Top Fungicide is applied as a foliar 

spray and can be used in block, alternating spray or tank-mix programs with other crop 
Aprovia Top Fungicide 

Page 7 

protection products. All applications should be made according to the use directions 

that follow. 

USE INFORMATION 

Application: Thorough coverage is necessary to provide good disease control. Make 

no more spray solution than is needed for application. Avoid spray overlap, as crop 

injury may occur. 

Adjuvants: For best performance, the addition of a spreading/penetrating type 

adjuvant such as organo-silicon blends with either non-ionic surfactants (NIS) or 

vegetable based crop oil concentrate (COC); or vegetable based COC (not mineral); or 

NIS with at least 90% concentration is recommended. When an adjuvant is to be used 

with this product, Syngenta recommends the use of a Chemical Producers and 

Distributors Association certified adjuvant. When an adjuvant is to be used with this 

product, Syngenta recommends the use of a Chemical Producers and Distributors 

Association certified adjuvant. 

Efficacy: Under certain conditions conducive to extended infection periods, use 

another registered fungicide for additional applications if the maximum amount of 

Aprovia Top Fungicide has been used. If resistant isolates to Group 7 or Group 3 

fungicides are present, efficacy can be reduced for certain diseases. The higher rates 

in the rate range and/or shorter spray intervals may be required under conditions of 

heavy infection pressure, with highly susceptible varieties, or when environmental 

conditions are conducive to disease. 

Integrated Pest Management (IPM): Aprovia Top Fungicide should be integrated into 

an overall disease and pest management strategy whenever the use of a fungicide is 

required. Cultural practices known to reduce disease development should be followed. 

Consult your local agricultural authorities for additional IPM strategies established for 

your area. Aprovia Top Fungicide may be used in State Agricultural Extension advisory 

(disease forecasting) programs which recommend application timing based on 

environmental factors favorable for disease development. 

Resistance Management 

GROUP 11 3 FUNGICIDES

Aprovia Top Fungicide contains two fungicides - difenoconazole, a triazole fungicide in 

Group 3 and benzovindiflupyr, a succinate dehydrogenase inhibitor (SDHI) in Group 7. 

Fungal pathogens can develop resistance to products with the same mode of action 

when used repeatedly. Because resistance development cannot be predicted, use of 

this product should conform to resistance management strategies established for the 

crop and use area. Consult your local or state agricultural authorities for resistance 

management strategies that are complementary to those in this label. Resistance 

management strategies may include rotating and/or tank mixing with products having 
Aprovia Top Fungicide 

Page 8 

different modes of action or limiting the total number of applications per season. 

Syngenta encourages responsible resistance management to ensure effective longterm control of the fungal diseases on this label. Aprovia Top Fungicide should not be 

alternated or tank mixed with any fungicide to which resistance has already developed. 

As part of a resistance management strategy: 

x Apply no more than 2 sequential applications unless otherwise stated in the crop 

section. 

x When tank mixing or alternating, use an effective partner – one that provides 

satisfactory disease control when used alone at the mixture rate. 

x Apply early to keep fungal populations low. 

x Incorporate integrated pest management (IPM) practices into your program which 

can help reduce disease development and spread. 

Rotational Crops: Please see the following table for the crop rotational restrictions: 

Rotational Crops 

Planting Time From Last Aprovia Top 

Fungicide Application 

Canola 

Cucurbits vegetables 

Legumes, subgroup 6C 

Fruiting vegetables 

Potatoes 

Soybean 

Tomatoes 

Tuberous & Corm vegetable subgroup 0 days 

Cereals (wheat, barley, triticale, oat ,rye) 30 days 

Corn 

Corn, Sweet 

Cotton 

Peanuts 

60 days 

All other crops Intended for Food and Feed 180 days 

Crop Tolerance: Plant tolerance has been found to be acceptable for all crops on the 

label, however, not all possible tank-mix combinations have been tested under all 

conditions. When possible, it is recommended to test the combinations on a small 

portion of the crop to ensure that a phytotoxic response will not occur as a result of 

application. 

Greenhouse Use: To help manage fungicide resistance, do not use Aprovia Top 

Fungicide use for commercial transplant production. Do not apply to greenhouse 

tomatoes. 

Spray Drift Management: To avoid spray drift, do not apply when conditions favor drift 

beyond the target area. The interaction of many equipment and weather related factors 
Aprovia Top Fungicide 

Page 9 

determine the potential for spray drift. AVOIDING SPRAY DRIFT AT THE 

APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR AND THE 

GROWER. 

MIXING AND APPLICATION METHODS 

Spray Equipment 

Nozzles

x Equip sprayers with nozzles that provide accurate and uniform application. 

x Nozzles should be the same size and uniformly spaced across the boom. 

x Calibrate sprayer before use. 

x It is suggested that screens be used to protect the pump and to prevent nozzles 

from clogging. 

x Screens placed on suction side of pump should be 16-mesh or coarser. 

x Do not place a screen in the recirculation line. 

x Use 50-mesh or coarser screens between the pump and boom, and where required, 

at the nozzles. 

x Check nozzle manufacturer’s recommendations. 

Pump 

x Use a pump with capacity to: 

(1) Maintain 35-40 psi at nozzles. 

(2) Provide sufficient agitation in tank to keep mixture in suspension - this 

requires recirculation of 10% of tank volume per minute. 

x Use a jet agitator or liquid sparge tube for agitation. 

x Do not air sparge. 

For more information on spray equipment and calibration, consult sprayer 

manufacturer’s and state recommendations. For specific local directions and spray 

schedules, consult the current state agricultural recommendations. 

Mixing Instructions 

x Aprovia Top Fungicide is an emulsifiable concentrate (EC). 

x Prepare no more spray mixture than is required for the immediate operation. 

x Thoroughly clean spray equipment before using this product. 

x Agitate the spray solution before and during application. 

x Rinse spray tank thoroughly with clean water after each day’s use and dispose of 

pesticide rinsate by application to an already treated area. 
Aprovia Top Fungicide 

Page 10 

Aprovia Top Fungicide Alone (No Tank Mix)

x Add 1⁄2-Ҁ of the required amount of water to the spray or mixing tank. 

x With the agitator running, add Aprovia Top Fungicide to the tank. 

x Continue agitation while adding the remainder of the water. 

x Begin application of the spray solution after Aprovia Top Fungicide has completely 

dispersed into the mix water. 

x Maintain agitation until all of the mixture has been sprayed. 

Aprovia Top Fungicide + Tank Mixtures: Aprovia Top Fungicide is usually 

compatible with all tank-mix partners listed on this label. To determine the physical 

compatibility of Aprovia Top Fungicide with other products, use a jar test. Using a quart 

jar, add the proportionate amounts of the products to 1 qt of water. Add wettable 

powders and water dispersible granular products first, then liquid flowables, and 

emulsifiable concentrates last. After thoroughly mixing, let stand for at least 5 minutes. 

If the combination remains mixed or can be remixed readily, it is physically compatible. 

Once compatibility has been proven, use the same procedure for adding required 

ingredients to the spray tank. 

Tank Mixtures: All directions for use, crops/sites, use rates, dilution rates, precautions, 

and limitations which appear on the tank-mix product label must be observed. The label 

dosage for the tank-mix partner is not to be exceeded, and the most restrictive label 

precautions and limitations are to be followed. 

Mixing in the Spray Tank 

x Add 1⁄2-Ҁ of the required amount of water to the spray or mixing tank. 

x With the agitator running, add the tank-mix partner(s) into the tank in the same order 

as described above. 

x Allow the material to completely dissolve and disperse into the mix water. Continue 

agitation while adding the remainder of the water and Aprovia Top Fungicide to the 

spray tank. 

x Allow Aprovia Top Fungicide to completely disperse. 

x Spray the mixture with the agitator running. 

Application Instructions 

Aprovia Top Fungicide may be applied with all types of spray equipment commonly 

used for making ground and aerial applications. Proper adjustments and calibration of 

spraying equipment to give good canopy penetration and coverage is essential for good 

disease control. 

RECOMMENDATION: When using greater than 40 gallons per acre, it is advised to 

add a tank-mix adjuvant unless prohibited by the Specific use Restrictions for the listed 

crop, of either NIS (minimum of 1% of total spray volume in tank) or oil such as crop oil 

or horticultural spray oil (minimum of 1% total spray volume in tank). 
Aprovia Top Fungicide 

Page 11 

Ground Application 

x Apply in a minimum of 10 gallons of water per acre, unless specified otherwise. 

x Do not apply through any ultra-low volume (ULV) spray system. 

x Thorough coverage is necessary to provide good disease control. 

Ground Application Precautions 

OBSERVE THE FOLLOWING PRECAUTIONS WHEN SPRAYING IN THE VICINITY 

OF AQUATIC AREAS SUCH AS LAKES, RESERVOIRS, RIVERS, PERMANENT 

STREAMS, MARSHES OR NATURAL PONDS, ESTUARIES, AND COMMERCIAL 

FISH PONDS. 

x Do not apply within 15 ft of bodies of water such as lakes, reservoirs, rivers, 

permanent streams, natural ponds, marshes or estuaries. 

x Shut off the sprayer when row ends. 

x Do not cultivate within 15 ft of aquatic areas in order to allow growth of a vegetative 

filter strip. 

x Do not apply when weather conditions favor drift to aquatic areas. Do not apply 

when gusts or sustained winds exceed 10 mph. 

x Do not apply during a temperature inversion. Mist or fog may indicate the presence 

of an inversion in humid areas. 

x For perennial crops such as tree crops and grapes: Spray last three rows windward 

of aquatic areas using nozzles on one side only, with spray directed away from 

aquatic areas. Adjust or turn off top nozzles to prevent spray going over the tops of 

trees. Shut off nozzles on the side away from the grove/orchard when spraying the 

outside row. Shut off nozzles when turning at ends of row or passing tree gaps in 

the rows. 

Aerial Application 

x Use only on crops where aerial applications are indicated. 

x Thorough coverage is necessary to provide good disease control. 

x Apply in a minimum of 2 gallons of water per acre unless specified otherwise. 

x Avoid application under conditions when uniform coverage cannot be obtained or 

when excessive spray drift may occur. 

x Do not apply directly to humans or animals. 

x Do not apply through any ultra-low volume (ULV) spray system. 

Aerial Spray Precautions 

Observe the following precautions when spraying in the vicinity of aquatic areas such as 

lakes, reservoirs, rivers, permanent streams, marshes or natural ponds, estuaries and 

commercial fish ponds. 
Aprovia Top Fungicide 

Page 12 

x Do not apply by air within 150 ft of lakes, reservoirs, rivers, permanent streams, 

marshes or natural ponds, estuaries and commercial fish ponds. 

x For aerial applications, mount the spray boom on the aircraft so as to minimize the 

drift caused by wing tip vortices. Use the minimum practical boom length, which 

must not exceed 75% of wing span or rotor diameter. 

x Use the largest droplet size consistent with good pest control. Formation of very 

small droplets may be minimized by appropriate nozzle selection, by orientating 

nozzles away from the air stream as much as possible, and by avoiding excessive 

spray boom pressure. 

x Release spray at the lowest height consistent with pest control and flight safety. Do 

not make applications more than 10 feet above the crop canopy. 

x Risk of exposure to aquatic areas can be reduced by avoiding applications when 

wind direction is toward the aquatic area. 

x Do not apply when weather conditions favor drift to aquatic areas. Do not apply 

when gusts or sustained winds exceed 10 mph. 

x Low humidity and high temperatures increase the evaporation rate of spray droplets 

and therefore the likelihood of increased spray drift to aquatic area. Avoid spraying 

during conditions of low humidity and/or high temperatures. 

x Do not apply during a temperature inversion. Mist or fog may indicate the presence 

of an inversion in humid areas. 

Application Through Irrigation Systems (Chemigation) 

x Use only on crops where chemigation is specified on this label. 

x Apply this product only through center pivot, solid set, hand move, or moving wheel 

irrigation systems. Do not apply this product through any other type of irrigation 

system. 

x Crop injury, lack of effectiveness, or illegal pesticide residues in the crop can result 

from non-uniform distribution of the product in the water. 

x Apply in 0.1-0.25 inches/acre. Excessive water may reduce efficacy. 

x If you have questions about calibration, you should contact State Extension Service 

specialists, equipment manufacturers, or other experts. 

x Do not connect an irrigation system (including greenhouse systems) used for 

pesticide application to a public water system, unless the pesticide label-prescribed 

safety devices for public water systems are in place. 

x A person knowledgeable of the chemigation system and responsible for its 

operation, or under the supervision of the responsible person, shall shut the system 

down and make necessary adjustments should the need arise. 

Operating Instructions 

1. The system must contain a functional check-valve, vacuum relief valve, and low 

pressure drain appropriately located on the irrigation pipeline to prevent watersource contamination from backflow. 
Aprovia Top Fungicide 

Page 13 

2. The pesticide injection pipeline must contain a functional, automatic, quickclosing check-valve to prevent the flow of fluid back toward the injection pump. 

3. The pesticide injection pipeline must also contain a functional, normally closed, 

solenoid-operated valve located on the intake side of the injection pump and 

connected to the system interlock to prevent fluid from being withdrawn from the 

supply tank when the irrigation system is either automatically or manually shut 

down. 

4. The system must contain functional interlocking controls to automatically shut off 

the pesticide injection pump when the water pump motor stops. 

5. The irrigation line or water pump must include a functional pressure switch which 

will stop the water pump motor when the water pressure decreases to the point 

where pesticide distribution is adversely affected. 

6. Systems must use a metering pump, such as a positive displacement injection 

pump (e.g., diaphragm pump), effectively designed and constructed of materials 

that are compatible with pesticides and capable of being fitted with a system 

interlock. 

7. Do not apply when wind speed favors drift beyond the area intended for 

treatment. 

Center Pivot Irrigation Equipment 

Notes: (1) Use only with drive systems which provide uniform water distribution. (2) Do 

not use end guns when chemigating Aprovia Top Fungicide through center pivot 

systems because of non-uniform application. 

x Determine the size of the area to be treated. 

x Determine the time required to apply ǩ-1⁄2 inch of water over the area to be treated 

when the system and injection equipment are operated at normal pressures as 

recommended by the equipment manufacturer. When applying Aprovia Top 

Fungicide through irrigation equipment use the lowest obtainable water volume while 

maintaining uniform distribution. Run the system at 80-95% of the manufacturer’s 

rated capacity. 

x Using water, determine the injection pump output when operated at normal line 

pressure. 

x Determine the amount of Aprovia Top Fungicide required to treat the area covered 

by the irrigation system. 

x Add the required amount of Aprovia Top Fungicide and sufficient water to meet the 

injection time requirements to the solution tank. 

x Make sure the system is fully charged with water before starting injection of the 

Aprovia Top Fungicide solution. Time the injection to last at least as long as it takes 

to bring the system to full pressure. 
Aprovia Top Fungicide 

Page 14 

x Maintain constant solution tank agitation during the injection period. 

x Continue to operate the system until the Aprovia Top Fungicide solution has cleared 

the sprinkler head. 

Solid Set, Hand Move, and Moving Wheel Irrigation Equipment 

x Determine the acreage covered by the sprinklers. 

x Fill injector solution tank with water and adjust flow rate to use the contents over a 

20- to 30-minute interval. When applying Aprovia Top Fungicide through irrigation 

equipment use the lowest obtainable water volume while maintaining uniform 

distribution. 

x Determine the amount of Aprovia Top Fungicide required to treat the area covered 

by the irrigation system. 

x Add the required amount of Aprovia Top Fungicide into the same quantity of water 

used to calibrate the injection period. 

x Operate the system at the same pressure and time interval established during the 

calibration. 

x Stop injection equipment after treatment is completed. Continue to operate the 

system until the Aprovia Top Fungicide solution has cleared the last sprinkler head. 

SPECIFIC INSTRUCTIONS FOR PUBLIC WATER SYSTEMS 

1. Public water system means a system for the provision to the public of piped 

water for human consumption if such system has at least 15 service connections 

or regularly serves an average of at least 25 individuals daily at least 60 days out 

of the year. 

2. Chemigation systems connected to public water systems must contain a 

functional, reduced-pressure zone, back-flow preventer (RPZ) or the functional 

equivalent in the water supply line upstream from the point of pesticide 

introduction. As an option to the RPZ, the water from the public water system 

should be discharged into a reservoir tank prior to pesticide introduction. There 

shall be a complete physical break (air gap) between the outlet end of the fill pipe 

and the top or overflow rim of the reservoir tank of at least twice the inside 

diameter of the fill pipe. 

3. The pesticide injection pipeline must contain a functional, automatic, quickclosing check valve to prevent the flow of fluid back toward the injection pump. 

4. The pesticide injection pipeline must contain a functional, normally closed, 

solenoid-operated valve located on the intake side of the injection pump and 

connected to the system interlock to prevent fluid from being withdrawn from the 

supply tank when the irrigation system is either automatically or manually shut 

down. 
Aprovia Top Fungicide 

Page 15 

5. The system must contain functional interlocking controls to automatically shut off 

the pesticide injection pump when the water pump motor stops, or in cases 

where there is no water pump, when the water pressure decreases to the point 

where pesticide distribution is adversely affected. 

6. Systems must use a metering pump, such as a positive displacement injection 

pump (e.g., diaphragm pump) effectively designed and constructed of materials 

that are compatible with pesticides and capable of being fitted with a system 

interlock. 

7. Do not apply when wind speed favors drift beyond the area intended for 

treatment. 

Overview of Key Information 

Crop*

Maximum Product 

Rate/A/application

(fl oz/A) 

Maximum total 

fl oz/A/season 

Pre-Harvest 

Interval (PHI) 

(days) 

Minimum ReTreatment

Interval (days)

Blueberries 

(lowbush only) 

13.5 13.5 365 na 

Rapeseed 

Subgroup 20A 

(Canola) 

13.5 13.5 30 na 

Cucurbit 

Vegetables Crop 

Group 9 

13.5 53.6 0 7 

Fruiting Vegetable 

Crop Group 8-10 

(tomatoes/peppers) 

13.5 53.6 0 7 

Grape and Small 

Fruit Vine Climbing 

(Subgroup 13-07F) 

13.5 40.5 21 14 

Pea and Bean, 

Dried Shelled, 

Except Soybean, 

Subgroup (6C) 

11 22 14 14 

Pome Fruit Group 

11-10 

9 35.2 30 7 

Soybean (forage, 

hay, hulls, and 

seed) 

9 18 14 14 

Vegetables, 

Tuberous & Corm 

Subgroup 1C 

(except potatoes) 

13.5 27 14 14 

*For specific crops in a group and use directions, refer to the Specific Directions for Use 
Aprovia Top Fungicide 

Page 16 

For best performance, the addition of a spreading/penetrating type adjuvant such as 

organo-silicon blends with either non-ionic surfactants (NIS) or vegetable based crop oil 

concentrate (COC); or vegetable based COC (not mineral); or NIS with at least 90% 

concentration is recommended. 

For resistance management, make no more than two sequential applications of a Group 

7 fungicide unless otherwise specified in the Directions for Use. 
Aprovia Top Fungicide 

Page 17 

SPECIFIC DIRECTIONS FOR USE 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks 

Blueberries 

(lowbush 

only) 

Septoria leaf spot 

(Septoria spp.)

Leaf rust 

(Thekopsora minima) 

13.5 Apply only in the non-cropping year of 

production (i.e. vegetative or sprout 

phase of production). Apply at first sign 

of diseases. 

Make no more than one Aprovia Top 

application per season. 

The addition of a spreading/penetrating 

type adjuvant such as organo-silicon 

blends with either non-ionic surfactants 

(NIS) or vegetable based crop oils 

(COC); or vegetable based COC (not 

mineral); or NIS with at least 90% 

concentration is recommended. 

Optional language if label has a rate 

range: If disease pressure is high, use 

the highest rate.

Application: For best results, sufficient water volume must be used to provide thorough coverage. 

Aprovia Top Fungicide can be applied by ground or air.

Specific Use Restrictions: 

1) Do not apply more than 13.5 fl. oz/A/year of Aprovia Top Fungicide. 

2) Do not apply more than 0.068 lb ai/A/year of benzovindiflupyr-containing products. 

3) Do not apply within 1 year of harvest (365 day PHI). 
Aprovia Top Fungicide 

Page 18 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks 

Rapeseed 

Subgroup

20A

(Canola) 

For listing of 

crops in this 

group, see 

below 

 

Alternaria black spot 

(Alternaria brassicae) 

Black leg/Phoma 

(Leptosphaeria 

maculans) 

Cercospora leafspot 

(C. brassicicola) 

Head rot 

(Rhizoctonia solani) 

Leaf spot and pod rot 

(Alternaria alternata) 

Powdery mildew 

(Erysiphe polygoni) 

Suppression of: 

Southern blight 

(Sclerotium rolfsii) 

13.5 For Phoma control, apply during the 

rosette stage between 2nd true leaf and 

bolting. 

For Alternaria, make an application at 

the end of flowering/early pod set. For 

other foliar diseases, apply at first sign 

of disease. 

For head rot, apply at 50% flowering. 

Make no more than one Aprovia Top 

Fungicide application per season. 

The addition of a spreading/penetrating 

type adjuvant such as organo-silicon 

blends with either non-ionic surfactants 

(NIS) or vegetable based crop oils 

(COC); or vegetable based COC (not 

mineral); or NIS with at least 90% 

concentration is recommended. 

Application: For best results, sufficient water volume must be used to provide thorough coverage. 

Aprovia Top Fungicide can be applied by ground, air, or chemigation. For chemigation, apply in 0.1-0.25 

inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy.

Complete list of Oilseed subgroup 20A: Borage, crambe, cuphea, echium, flax seed, gold of pleasure, 

hare’s ear mustard, lesquerella, lunaria, meadowfoam, milkweed, mustard seed, oil radish, poppy seed, 

rapeseed, sesame, sweet rocket and cultivars and/or hybrids of theses

Specific Use Restrictions: 

1) Do not apply more than 13.5 fl oz/A/year of Aprovia Top Fungicide. 

2) Do not apply more than 0.068 lb ai/A/year of benzovindiflupyr-containing products. 

3) Do not apply more than 0.113 lb ai/A/year of difenoconazole-containing products. 

4) Do not apply within 30 days of harvest (30 day PHI). 
Aprovia Top Fungicide 

Page 19 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks

Cucurbit 

Vegetables 

Crop Group 

9

For listing of 

crops in this 

group, see 

below 

Alternaria Leaf Blight 

(A. cucumerina) 

Alternaria Leaf Spot 

(A. alternata) 

Anthracnose 

(Colletotrichum 

orbiculare) 

Belly Rot 

(Rhizoctonia solani) 

Cercospora Leaf Spot 

(C. citrullina) 

Gummy Stem Blight 

(Didymella bryoniae) 

Myrothecium Canker 

(M. roridum) 

Phoma Blight 

(P. exigua) 

Phyllosticta Leaf Spot 

(P. cucurbitacearum) 

Plectosporium Blight 

(P. tabacinum) 

Powdery Mildew 

(Sphaerotheca 

fuliginea, Erysiphe 

cichoracearum) 

Septoria Leaf Blight 

(S. cucurbitacearum) 

Scab 

(Cladosporium 

cucumerinum) 

Target Spot 

(Corynespora 

cassiicola) 

8.5 – 13.5 Begin applications prior to disease onset 

when conditions are conducive for disease. 

Apply Aprovia Top Fungicide on a 7- to 14-

day schedule. 

No more than two applications of Aprovia 

Top may be applied on a 7-day interval. All 

other applications must be applied no closer 

than a 14-day interval. For resistance 

management, do not apply more than 2 

consecutive applications before switching to 

a non-Group 7 fungicide. 

For belly rot control, the first application 

should be made at the 1- to 3-leaf crop stage 

with a second application just prior to vine tip 

or 10-14 days later, whichever occurs first. 

The addition of a spreading/penetrating type 

adjuvant such as organo-silicon blends with 

either non-ionic surfactants (NIS) or 

vegetable based crop oils (COC); or 

vegetable based COC (not mineral); or NIS 

with at least 90% concentration is 

recommended. 

Optional language if label has a rate range: 

If disease pressure is high, use the highest 

rate. 

Optional language if label has a single rate 

and interval range: If disease pressure is 

high, use the shortest interval. 

Optional language if label has a rate range 

and interval range: If disease pressure is 

high, use the shortest interval and highest 

rate. 

Application: For best results, sufficient water volume must be used to provide thorough coverage. 

Aprovia Top Fungicide can be applied by ground or chemigation. A minimum of 15 gal./A for ground 

application is recommended (20 for gummy stem blight). For chemigation, apply in 0.1-0.25 inches/A of 

water. Chemigation with excessive water may lead to a decrease in efficacy.

Complete list of Cucurbit Vegetables Crop Group 9: Chayote (fruit); Chinese waxgourd (Chinese 

preserving melon); citron melon; cucumber; gherkin; gourd, edible (includes hyotan, cucuzza, hechima, 

Chinese okra); Momordica spp. (includes balsam apple, balsam pear, bittermelon, Chinese cucumber); 

muskmelon (includes cantaloupe); pumpkin; squash, summer; squash, winter (includes butternut squash, 

calabaza, hubbard squash, acorn squash, spaghetti squash); watermelon 

Specific Use Restrictions: 

1) Do not apply more than 53.6 fl oz/A/year of Aprovia Top Fungicide.

2) Do not apply more than 0.272 lb ai/A/year of benzovindiflupyr-containing products.

3) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products.

4) May be applied the day of harvest (0-day PHI).
Aprovia Top Fungicide 

Page 20 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks

Fruiting

Vegetable 

Crop Group 

8-10 (except 

tomatoes), 

see

TOMATO

section

For listing of 

crops in this 

group, see 

below 

See the 

Tomato

section for 

specific

directions.

Anthracnose 

(Colletotrichum spp.)

Cercospora Leaf Spot 

(C. capsici) 

Gray Leaf Spot 

(Stemphyllium solani) 

Powdery Mildew 

(Oidiopsis sicula) 

Rhizoctonia stem rot 

(R. solani) 

Suppression only: 

Southern blight 

(Sclerotium rolfsii) 

8.5 – 13.5 Begin applications prior to disease 

development and continue throughout the 

season on a 7- to 10-day interval. 

No more than two applications of Aprovia 

Top may be applied on a 7-day interval. All 

other applications must be applied no closer 

than a 14-day interval. For resistance 

management, do not apply more than 2 

consecutive applications before switching to 

a non-Group 7 fungicide. 

The addition of a spreading/penetrating type 

adjuvant such as organo-silicon blends with 

either non-ionic surfactants (NIS) or 

vegetable based crop oils (COC); or 

vegetable based COC (not mineral); or NIS 

with at least 90% concentration is 

recommended. 

Optional language if label has a rate range: 

If disease pressure is high, use the highest 

rate. 

Optional language if label has a single rate 

and interval range: If disease pressure is 

high, use the shortest interval. 

Optional language if label has a rate range 

and interval range: If disease pressure is 

high, use the shortest interval and highest 

rate. 

Application: For best results, sufficient water volume must be used to provide thorough coverage. 

Aprovia Top Fungicide can be applied by ground or chemigation application. A minimum of 15 gal./A for 

ground applications is recommended.

Complete list of Fruiting vegetables (except for types of tomatoes) Crop Group 8-10: African 

eggplant, bell pepper; cocna; eggplant, garden huckleberry; goji berry; groundcherry; martynia; naranjilla; 

okra; pea eggplant; pepino; nonbell pepper; roselle; scarlet eggplant; sunberry

Specific Use Restrictions: 

1) Do not apply to greenhouse peppers.

2) Do not apply more than 53.6 oz/A/year of Aprovia Top Fungicide.

3) Do not apply more than 0.272 lb ai/A/year of benzovindiflupyr-containing products.

4) Do not apply more than 0.46 lb ai/A/year of a difenoconazole-containing product.

5) May be applied the day of harvest (0-day PHI).
Aprovia Top Fungicide 

Page 21 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks

Grape and 

Small Fruit 

Vine

Climbing

(Subgroup 

13-07F) 

For listing of 

crops in this 

group, see 

below 

Alternaria Rot 

(A. alternata) 

Angular Leaf Spot 

(Mycosphearella 

angulata) 

Anthracnose 

(Elsinoe ampelina) 

Black Rot 

(Guignarda bidwellii) 

Leaf Blight 

(Pseudocercospora 

vitis) 

Phomopsis Cane and 

Leaf Spot 

(P. viticola) 

Powdery Mildew 

(Erysiphe necator) 

Rotbrenner 

(Pseudopezicula 

tracheiphila) 

Septoria Leaf Spot 

(S. ampelina) 

8.5 – 13.5 For powdery mildew, begin at bud break and 

apply on a 14 - to 21-day interval. 

For Phomopsis diseases, apply at bud break 

before shoots are 0.5 inches in length, and 

then again when shoots are 5-6 inches in 

length. 

For black rot, begin when shoot length is 1-3 

inches and continue on a 14-day interval. 

For all other diseases, begin applications prior 

to disease onset when conditions are 

conducive for disease. Apply Aprovia Top 

Fungicide on a 14-day schedule. 

For resistance management, make no more 

than 2 applications before alternating to 

another fungicide with a non-Group 7 mode of 

action. 

Optional language for adjuvant 

recommendation: The addition of a 

spreading/penetrating type adjuvant such as 

organo-silicon blends with either non-ionic 

surfactants (NIS) or vegetable based crop oils 

(COC); or vegetable based COC (not mineral); 

or NIS with at least 90% concentration is 

recommended. 

Optional language if label has a rate range: If 

disease pressure is high, use the highest rate. 

PRECAUTION: On V. labrusca, V. labrusca

hybrids, and other non-viniferea hybrids 

where sensitivity is not known - the use of 

Aprovia Top Fungicide by itself or in tank 

mixtures with materials that may increase 

uptake (adjuvants, foliar fertilizers) may 

result in leaf burning or other phytotoxic 

effects.

Application: For best results, sufficient water volume must be used to provide thorough coverage. 

Aprovia Top Fungicide can be applied by ground application. A minimum of 15 gal./A for ground 

applications is recommended. For aerial applications, a minimum of 10 gal./A of water is recommended.

Complete list of Small fruit vine climbing subgroup (except fuzzy kiwifruit) subgroup 13-07F: Amur 

river grape, gooseberry, grape; kiwifruit (hardy); maypop; schisandra berry

Specific Use Restrictions: 

1) Do not apply more than 40.5 fl oz./A/year of Aprovia Top Fungicide.

2) Do not apply more than 0.204 lb ai/A per year of benzovindiflupyr-containing products.

3) Do not apply more than 0.46 lb ai/A per year of difenoconazole-containing products.

4) Do not apply within 21 days of harvest (21-day PHI).
Aprovia Top Fungicide 

Page 22 

Crop Target Diseases

Use Rate 

Fl Oz 

Product/A Remarks

Pea and 

Bean, Dried 

Shelled,

Except

Soybean, 

Subgroup 6C 

For listing of 

crops in this 

group, see 

below 

Alternaria Blight 

(A. alternata) 

Ascochyta Blight 

(A. rabiei) 

Powdery Mildew 

(Leveillula taurica) 

Rust 

(Uromyces cicerisarietini) 

Asian Soybean Rust 

(Phakopsora pachyrhizi)

Anthracnose 

(Colletotrichum spp.)

Mycosphaerella blight 

(Mycosphaerella spp.)

Cercospora leaf spot 

(Cercospora spp.)

8.5 – 11 Begin applications prior to disease onset 

when conditions are conducive for disease. 

Apply Aprovia Top Fungicide on a 14-day 

schedule. 

For resistance management, make no more 

than 2 applications before alternating to 

another fungicide with a non-Group 7 mode 

of action. 

The addition of a spreading/penetrating type 

adjuvant such as organo-silicon blends with 

either non-ionic surfactants (NIS) or 

vegetable based crop oils (COC); or 

vegetable based COC (not mineral); or NIS 

with at least 90% concentration is 

recommended. 

Optional language if label has a rate range: 

If disease pressure is high, use the highest 

rate. 

Application: For best results, sufficient water volume must be used to provide thorough coverage. 

Aprovia Top Fungicide can be applied by ground, air, or chemigation. A minimum of 15 gal./A for ground 

applications is recommended. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with 

excessive water may lead to a decrease in efficacy.

Dried Shelled pea and bean (except soybean) subgroup 6C: Dried cultivars of bean (Lupinus); bean 

(Phaseolus) (includes field bean, kidney bean, lima bean (dry), navy bean, pinto bean, tepary bean); 

bean (Vigna) (includes adzuki bean, black-eyed pea, catjang, cowpea, crowder pea, moth bean, mung 

bean, rice bean, southern pea, urd bean); broad bean (dry); chickpea; guar; lablab bean; lentil; pea 

(Pisum) (includes field pea); pigeon pea

Specific Use Restrictions: 

1) Do not apply more than 22 fl oz/A/year of Aprovia Top Fungicide. 

2) Do not apply more than 0.112 lb ai/A/year of a benzovindiflupyr-containing product. 

3) Do not apply more than 0.46 lb ai/A/year of a difenoconazole-containing product. 

4) Do not apply within 14 days of harvest (14-day PHI). 
Aprovia Top Fungicide 

Page 23 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks 

Pome Fruit 

Group 11-10 

For listing of 

crops in this 

group, see 

below. 

Apple Scab 

(Venturia inaequalis) 

Pear Scab 

(V. piris) 

Alternaria blotch 

Alternaria rot 

(Alternaria spp.)

Cedar apple rust 

(Gymnosporangium 

juniper-virginianae) 

Quince rust 

(Gymnosporangium 

spp.)

Flyspeck and Sooty 

blotch 

Suppression: 

Powdery mildew 

(Podosphaera 

leucotricha) 

Bitter rot 

(Glomerella cingulata) 

Black rot 

(Botryosphaeria 

obtusa)

Brooks fruit spot 

(Mycosphaerella 

pomi) 

White rot 

(Botryosphaeria 

dothidea) 

5.5 – 9 Scab – Protective Spray Schedule: 

Apply every 7-10 days starting at 1⁄4 to 1⁄2 inch 

green tip or when environmental conditions 

become conducive for scab. Continue through 

petal fall until the threat of primary scab is 

complete. For resistance management, 

combine Aprovia Top Fungicide with a 

protectant fungicide registered to control scab 

beginning at bloom. 

Scab – Curative Spray Schedule: 

Use a forecasting system beginning at green 

tip. Apply within 48 hours of the onset of an 

infection period. Apply a follow up spray within 

7 days. For resistance management, combine 

Aprovia Top Fungicide with a protectant 

fungicides registered to control scab beginning 

at bloom. 

Scab – Calendar spray 

Apply the high rate of Aprovia Top Fungicide 

on a 14 day interval beginning at pink. Make 

no more than 2 consecutive applications before 

alternating to a non-Group 7 registered 

fungicide. Be sure use according to that label. 

Rusts, leafspots, summer diseases – Begin 

applications preventively. Apply Aprovia Top 

Fungicide alone or in combination with other 

non-Group 7 fungicides. 

No more than two applications of Aprovia Top 

may be applied on a 7-day interval. All other 

applications must be applied no closer than a 

14-day interval. For resistance management, 

do not apply more than 2 consecutive 

applications before switching to a non-Group 7 

fungicide. 

Optional language for adjuvant 

recommendation: The addition of a 

spreading/penetrating type adjuvant such as 

organo-silicon blends with either non-ionic 

surfactants (NIS) or vegetable based crop oils 

(COC); or vegetable based COC (not mineral); 

or NIS with at least 90% concentration is 

recommended. 

Optional language if label has a rate range: If 

disease pressure is high, use the highest rate. 

Optional language if label has a single rate and 

interval range: If disease pressure is high, use 

the shortest interval. 

Optional language if label has a rate range and 

interval range: If disease pressure is high, use 
Aprovia Top Fungicide 

Page 24 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks 

the shortest interval and highest rate. 

The addition of a spreading/penetrating type 

adjuvant may enhance efficacy. 

Application: For best results, use sufficient water volume to provide thorough coverage. Aprovia Top 

Fungicide may be applied by ground or air application. 

RECOMMENDATION: When using greater than 40 gallons per acre, it is advised to add a tank-mix 

adjuvant unless prohibited by the Specific use Restrictions for the listed crop, of either NIS (minimum of 

1% of total spray volume in tank) or oil such as crop oil or horticultural spray oil (minimum of 1% total 

spray volume in tank). 

Pome Fruit Crop Group 11-10: Apple; azarole; crabapple; loquat; mayhaw; medlar; pear; pear, Asian; 

quince; quince, Chinese; quince, Japanese; tejocote; cultivars, varieties, and/or hybrids or these

Specific Use Restrictions: 

1) Do not apply more than 36 fl oz./A/year of Aprovia Top Fungicide. 

2) Do not apply more than 0.184 lb ai/A/year of benzovindiflupyr-containing products. 

3) Do not apply more than 0.33 lb ai/A/year of a difenoconazole-containing product. 

4) Do not apply within 30 days of harvest (30-day PHI). 
Aprovia Top Fungicide 

Page 25 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks 

Soybean 

(forage, hay, 

hulls, and 

seed) 

Aerial blight 

(R. solani) 

Alternaria Leaf Spot 

(Alternaria spp.)

Anthracnose 

(Colletotrichum 

truncatum) 

Asian Soybean Rust 

(Phakopsora 

pachyrhizi) 

Brown Spot 

(Septoria glycines) 

Cercospora Blight and 

Leaf Spot 

(C. kikuchii) 

Frogeye Leaf Spot 

(Cercospora sojina) 

Pod and Stem Blight 

(Diaporthe 

phaseolorum) 

Powdery Mildew 

(Microsphaera 

diffusa) 

Target Spot 

(Corynespora 

cassiicola) 

Suppression: 

Southern blight 

(Sclerotium rolfsii) 

9 Begin applications prior to disease onset when 

conditions are conducive for disease. Apply 

Aprovia Top Fungicide no closer than a 14 day 

interval. 

For resistance management, make no more 

than 2 applications before alternating to 

another fungicide with a non-Group 7 mode of 

action. 

The addition of a spreading/penetrating type 

adjuvant such as organo-silicon blends with 

either non-ionic surfactants (NIS) or vegetable 

based crop oils (COC); or vegetable based 

COC (not mineral); or NIS with at least 90% 

concentration is recommended. 

Application: For best results, sufficient water volume must be used to provide thorough coverage. 

Aprovia Top Fungicide can be applied by ground, air, or chemigation. For chemigation, apply in 0.1-0.25 

inches/A of water. Chemigation with excessive water may lead to a decrease in efficacy. 

Specific Use Restrictions: 

1) Do not apply more than 18 oz/A/year of Aprovia Top Fungicide. 

2) Do not apply more than 0.092 lb ai/A/year of a benzovindiflupyr-containing product. 

3) Do not apply more than 0.22 lb ai/A/year of a difenoconazole-containing product. 

4) Do not feed soybean hay, forage and silage. 

5) Do not apply within 14 days of harvest (14-day PHI). 
Aprovia Top Fungicide 

Page 26 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks 

Tomato 

Includes: 

Tomato, bush; 

Tomato, 

currant; 

Tomatillo; 

Tomato, tree 

including 

cultivars, 

varieties, 

and/or hybrids 

of these 

Anthracnose 

(Colletotrichum spp.)

Black Mold 

(A. alternata) 

Early Blight 

(Alternaria solani) 

Gray Leaf Spot 

(Stemphylium 

botryosum) 

Leaf Mold 

(Fulvia fulva) 

Powdery Mildew 

(Leveillula taurica) 

Septoria Leaf Spot 

(S. lycopersici) 

Rhizoctonia fruit rot 

(R. solani) 

Target Spot 

(Corynespora 

cassiicola) 

Suppression of: 

Southern blight 

(Sclerotium rolfsii) 

8.5 – 13.5 Begin applications prior to disease 

development and continue throughout the 

season on a 7- to 14-day interval. 

No more than two applications of Aprovia Top 

may be applied on a 7-day interval. All other 

applications must be applied no closer than a 

14-day interval. For resistance management, 

do not apply more than 2 consecutive 

applications before switching to a non-Group 7 

fungicide. 

Optional language for adjuvant 

recommendation: The addition of a 

spreading/penetrating type adjuvant such as 

organo-silicon blends with either non-ionic 

surfactants (NIS) or vegetable based crop oils 

(COC); or vegetable based COC (not mineral); 

or NIS with at least 90% concentration is 

recommended. 

Optional language if label has a rate range: If 

disease pressure is high, use the highest rate. 

Optional language if label has a single rate and 

interval range: If disease pressure is high, use 

the shortest interval. 

Optional language if label has a rate range and 

interval range: If disease pressure is high, use 

the shortest interval and highest rate. 

Application: For best results, use sufficient water volume to provide thorough coverage. Aprovia Top 

Fungicide may be applied by ground or chemigation. For chemigation, apply in 0.1-0.25 inches/A of 

water. Chemigation with excessive water may lead to a decrease in efficacy.

Specific Use Restrictions:

1) Do not apply to greenhouse tomatoes. 

2) Do not apply more than 53.6 fl oz/A/year of Aprovia Top Fungicide. 

3) Do not apply more than 0.272 lb ai/A/year of benzovindiflupyr-containing products. 

4) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products. 

5) May be applied the day of harvest (0-day PHI). 
Aprovia Top Fungicide 

Page 27 

Crop Target Diseases 

Use Rate 

Fl Oz 

Product/A Remarks 

Vegetables, 

Tuberous and 

Corm, 

Subgroup 1C 

For listing of 

crops in this 

group, see 

below. 

See Potatoes

for specific 

use directions.

Ascochyta Leaf Spot 

(A. cynarae) 

Black Dot 

(Colletotrichum 

coccodes) 

Brown Spot 

(Alternaria alternata) 

Early Blight 

(Alternaria spp.) 

Powdery Mildew 

(Erysiphe 

cichoracearum) 

Rust 

(Uromyces betae, 

Puccinia helianthi) 

Septoria Leaf Spot 

(Septoria spp.)

Suppression of: 

Stem rot 

(Sclerotium rolfsii) 

8.5 – 13.5 Begin applications prior to disease 

development and continue throughout the 

season on a 14-day interval. 

No more than two applications of Aprovia Top 

may be applied on a 7-day interval. All other 

applications must be applied no closer than a 

14-day interval. For resistance management, 

do not apply more than 2 consecutive 

applications before switching to a non-Group 7 

fungicide. 

The addition of a spreading/penetrating type 

adjuvant such as organo-silicon blends with 

either non-ionic surfactants (NIS) or vegetable 

based crop oils (COC); or vegetable based 

COC (not mineral); or NIS with at least 90% 

concentration is recommended. 

Optional language if label has a rate range: If 

disease pressure is high, use the highest rate. 

Optional language if label has a single rate and 

interval range: If disease pressure is high, use 

the shortest interval. 

Optional language if label has a rate range and 

interval range: If disease pressure is high, use 

the shortest interval and highest rate. 

Application: For best results, sufficient water volume must be used to provide thorough coverage. 

Aprovia Top Fungicide can be applied by ground or chemigation. A minimum of 15 gal./A for ground 

applications is recommended. For chemigation, apply in 0.1-0.25 inches/A of water. Chemigation with 

excessive water may lead to a decrease in efficacy. 

Complete list of Tuberous and corm vegetables subgroup 1C: Arracacha, Arrowroot, Artichoke 

(Chinese and Jerusalem), Canna (edible), Cassava (bitter and sweet), Chayote (root), Chufa, Dasheen 

(Taro), Ginger, Leren, Potato, Sweet Potato, Tanier, Tumeric, Yam (bean and true).

Specific Use Restrictions: 

1) Do not apply more than 27 fl oz/A/year of Aprovia Top Fungicide. 

2) Do not apply more than 0.136 lb ai/A/year of benzovindiflupyr-containing products. 

3) Do not apply more than 0.46 lb ai/A/year of difenoconazole-containing products. 

4) Do not apply within 14 days of harvest (14-day PHI). 
Aprovia Top Fungicide 

Page 28 

Aprovia Top Fungicide Rate Conversion Table 

Fl Oz Product/Acre Lb ai Difenoconazole Lb ai Benzovindiflupyr 

5.5 0.042 0.028 

6.0 0.045 0.030 

7.0 0.053 0.036 

8.5 0.064 0.043 

9.0 0.068 0.046 

10.0 0.076 0.051 

11.0 0.083 0.056 

12.0 0.091 0.061 

12.8 0.097 0.065 

13.5 0.103 0.068 

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

Pesticide Storage 

Store in original container only. Store in a cool, dry and well-ventilated place. Protect 

from excessive heat. Keep container closed when not in use. Do not store near food or 

feed. 

Pesticide Disposal 

Pesticide wastes may be toxic. Improper disposal of unused pesticide, spray mixture, 

or rinse water is a violation of Federal Law. If these wastes cannot be used according 

to label instructions, contact your State Pesticide or Environmental Control Agency, or 

the Hazardous Waste representative at the nearest EPA Regional Office for guidance in 

proper disposal methods. 

Container Handling [less than or equal to 5 gallons]

Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 

equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 

contents into application equipment or a mix tank. Fill the container 1⁄4 full with water 

and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix 

tank or store rinsate for later use and disposal. Drain for 10 seconds after the flow 

begins to drip. Repeat this procedure two more times. Then offer for recycling if 

available or puncture and dispose of in a sanitary landfill, or by incineration, or by other 

procedures approved by state and local authorities. 

Container Handling [greater than 5 gallons] 

Refillable container. Refill this container with pesticide only. Do not reuse this container 

for any other purpose. Cleaning the container before final disposal is the responsibility of 

the person disposing of the container. Cleaning before refilling is the responsibility of the 
Aprovia Top Fungicide 

Page 29 

person refilling. To clean container before final disposal, empty the remaining contents 

from this container into application equipment or a mix tank. Fill the container about 10 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Pour or pump rinsate into application equipment or rinsate collection system. 

Repeat this rinsing procedure two more times. Then offer for recycling if available or 

puncture and dispose of in a sanitary landfill, or by incineration, or by other procedures 

allowed by state and local authorities. 

Container Handling [greater than 5 gallons] 

Non-refillable container. Do not reuse or refill this container. Triple rinse container (or 

equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining 

contents into application equipment or a mix tank. Fill the container 1⁄4 full with water. 

Replace and tighten closures. Tip container on its side and roll it back and forth, 

ensuring at least one complete revolution, for 30 seconds. Stand the container on its 

end and tip it back and forth several ties. Turn the container over onto its other end and 

tip it back and forth several times. Empty the rinsate into application equipment or a mix 

tank or store rinsate for later use or disposal. Repeat this procedure two more times. 

Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by 

incineration, or by other procedures approved by state and local authorities. 

CONTAINER IS NOT SAFE FOR FOOD, FEED, OR DRINKING WATER. 

AproviaTM Top is a trademark of a Syngenta Group Company 

Viton® is a trademark of E.I. DuPont de Nemours and Company. 

©201X Syngenta 

For non-emergency (e.g., current product information), call 

Syngenta Crop Protection at 1-800-334-9481. 

Manufactured for: 

Syngenta Crop Protection, LLC 

P.O. Box 18300 

Greensboro, North Carolina 27419-8300 

Aprovia Top Fungicide NEW-Version D – bb – 8-26-15 

000100-XRUTA.20121126D.APROVIA.TOP.FUNGICIDE.NEW.pdf 

Aprovia Top Fungicide NEW-Version E – bb – 8-27-15 

000100-XRUTA.20121126E.APROVIA.TOP.FUNGICIDE.NEW.pdf