[Federal Register Volume 72, Number 41 (Friday, March 2, 2007)]
[Notices]
[Pages 9546-9547]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E7-3701]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Toxicology Program (NTP); Liaison and Scientific Review 
Office; Meeting of the NTP Board of Scientific Counselors Technical 
Reports Review Subcommittee

AGENCY: National Institute of Environmental Health Sciences (NIEHS), 
National Institutes of Health (NIH).

ACTION: Meeting announcement and request for comments.

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SUMMARY: Pursuant to Public Law 92-463, notice is hereby given of a 
meeting of the NTP Board of Scientific Counselors Technical Reports 
Review Subcommittee (TRR Subcommittee). The primary agenda topic is the 
peer review of the findings and conclusions presented in eight draft 
NTP Technical Reports of rodent toxicology and carcinogenicity studies 
in rats and mice conducted by the NTP (see Preliminary Agenda below). 
The TRR Subcommittee meeting is open to the public with time scheduled 
for oral public comment. The NTP also invites written comments on any 
draft technical report discussed at the meeting (see Request for 
Comments, below). The TRR Subcommittee deliberations on the draft 
technical reports will be reported to the NTP Board of Scientific 
Counselors (BSC) at a future date.

DATES: The TRR Subcommittee meeting will be held on May 16 and 17, 
2007. All individuals who plan to attend are encouraged to register 
online by May 9, 2007, at the NTP Web site (http://ntp.niehs.nih.gov/ 
select ``Calendar of Upcoming Events''). Written comments on the draft 
reports should be received by May 2, 2007. Persons needing special 
assistance, such as sign language interpretation or other reasonable 
accommodation in order to attend, should contact 919-541-2475 (voice), 
919-541-4644 TTY (text telephone), through the Federal TTY Relay System 
at 800-877-8339, or by e-mail to <a href="/cdn-cgi/l/email-protection#a7c9cec2cfd4c8c2c2c8e7c9cec2cfd489c9cecf89c0c8d1"><span class="__cf_email__" data-cfemail="d0beb9b5b8a3bfb5b5bf90beb9b5b8a3febeb9b8feb7bfa6">[email protected]</span></a>. Requests 
should be made at least 7 days in advance of the event.

ADDRESSES:  The TRR Subcommittee meeting will be held in the Rodbell 
Auditorium, Rall Building at the NIEHS, 111 T. W. Alexander Drive, 
Research Triangle Park, NC 27709. Public comments and any other 
correspondence should be submitted to Dr. Barbara Shane, Executive 
Secretary for the NTP Board (NTP Liaison and Scientific Review Office, 
NIEHS, P.O. Box 12233, MD A3-01, Research Triangle Park, NC 27709; 
telephone: 919-541-4253, fax: 919-541-0295; or e-mail: 
<a href="/cdn-cgi/l/email-protection#2d5e454c43486d434448455e03434445034a425b"><span class="__cf_email__" data-cfemail="4a39222b242f0a24232f223964242322642d253c">[email protected]</span></a>).

SUPPLEMENTARY INFORMATION:

Background

    The primary agenda topic is the peer review of the findings and 
conclusions of eight draft NTP Technical Reports of rodent toxicology 
and carcinogenicity studies conducted by the NTP (see Preliminary 
Agenda below) in rats and mice.

Attendance and Registration

    The meeting is scheduled for May 16-17, 2007, from 8:30 a.m. to 
adjournment and is open to the public with attendance limited only by 
the space available. Individuals who plan to

[[Page 9547]]

attend are encouraged to register online at the NTP Web site by May 9, 
2007, at http://ntp.niehs.nih.gov/ select ``Advisory Boards and 
Committees'' to facilitate access to the NIEHS campus. Please note that 
a photo ID is required to access the NIEHS campus. The NTP is making 
plans to videocast the meeting through the Internet at http://www.niehs.nih.gov/external/video.htm.

Availability of Meeting Materials

    A copy of the preliminary agenda, committee roster, and any 
additional information, when available, will be posted on the NTP Web 
site (http://ntp.niehs.nih.gov/ select ``Calendar of Upcoming Events'') 
or may be requested in hardcopy from the Executive Secretary (see 
ADDRESSES above). Draft NTP Technical Reports will be posted on the NTP 
Web site (http://ntp.niehs.nih.gov/ select ``Calendar of Upcoming 
Events'') after April 2, 2007. Following the meeting, summary minutes 
will be prepared and made available on the NTP Web site.

Request for Comments

    Public input at this meeting is invited and time is set aside for 
the presentation of public comments on any draft technical report. Each 
organization is allowed one time slot per agenda topic. At least 7 
minutes will be allotted to each speaker, and if time permits, may be 
extended to 10 minutes at the discretion of the chair. Persons wishing 
to make an oral presentation are asked to notify Dr. Barbara Shane via 
online registration, phone, or e-mail (see ADDRESSES above) by May 2, 
2007, and if possible, to send a copy of the statement or talking 
points at that time. Written comments on the draft reports are also 
welcome and should also be received by May 2, 2007, to enable review by 
the TRR Subcommittee and NTP staff prior to the meeting. Written 
statements can supplement and may expand the oral presentation. If 
registering on-site and reading from written text, please bring 40 
copies of the statement for distribution to the TRR Subcommittee and 
NTP staff and to supplement the record. Written comments received in 
response to this notice will be posted on the NTP Web site. Persons 
submitting written comments should include their name, affiliation, 
mailing address, phone, fax, e-mail, and sponsoring organization (if 
any) with the document. Registration for oral comments will also be 
available on-site, although time allowed for presentation by on-site 
registrants may be less than that for pre-registered speakers and will 
be determined by the number of persons who register at the meeting.

Background Information on the NTP Board of Scientific Counselors

    The NTP Board of Scientific Counselors (BSC) is a technical 
advisory body comprised of scientists from the public and private 
sectors who provide primary scientific oversight to the overall program 
and its centers. Specifically, the BSC advises the NTP on matters of 
scientific program content, both present and future, and conducts 
periodic review of the program for the purposes of determining and 
advising on the scientific merit of its activities and their overall 
scientific quality. The TRR Subcommittee is a standing subcommittee of 
the BSC. BSC members are selected from recognized authorities 
knowledgeable in fields such as toxicology, pharmacology, pathology, 
biochemistry, epidemiology, risk assessment, carcinogenesis, 
mutagenesis, molecular biology, behavioral toxicology and 
neurotoxicology, immunotoxicology, reproductive toxicology or 
teratology, and biostatistics. Its members are invited to serve 
overlapping terms of up to four years. BSC and TRR Subcommittee 
meetings are held annually or biannually.

    Dated: February 22, 2007.
Samuel H. Wilson,
Deputy Director, National Institute of Environmental Health Sciences 
and National, Toxicology Program.

Preliminary Agenda--National Toxicology Program (NTP) Board of 
Scientific Counselors Technical Reports Review

Subcommittee Meeting--May 16-17, 2007

Rodbell Auditorium, Rall Building, National Institute of Environmental 
Health Sciences--111 TW Alexander Drive, Research Triangle Park, NC 
27709

NTP Technical Reports (TR) Scheduled for Review
<bullet> TR 550: Cresols (CASNR 1319-77-3)
    [cir] Used as solvents, disinfectants, preservatives, and in the 
production of fragrances, antioxidants, dyes, pesticides, and resins
<bullet> TR 542: Cumene (CASNR 98-82-8)
    [cir] Used as a solvent and in the production of phenol, acetone 
and [alpha]-methylstyrene
<bullet> TR 547: Ethinyl Estradiol (CASNR 57-63-6)--Multigenerational 
Study
    [cir] Synthetic steroidal estrogen; used as a component of oral 
contraceptives
<bullet> TR 548: Ethinyl Estradiol (CASNR 57-63-6)--2-year bioassay
    [cir] Synthetic steroidal estrogen; used as a component of oral 
contraceptives
<bullet> TR 541: Formamide (CASNR 75-12-7)
    [cir] Used as a solvent, water softener, in water soluble inks and 
as an intermediate in organic syntheses
<bullet> TR 551 Isoeugenol (CASNR 97-54-1)
    [cir] Used as a food flavoring agent, fragrance, in the manufacture 
of vanillin, and to sedate fish; found naturally in cloves, tobacco and 
many other plants; prepared synthetically by heating eugenol
<bullet> TR 552: Propargyl Alcohol CASNR 107-19-7)
    [cir] Used as a chemical intermediate, corrosion inhibitor, solvent 
stabilizer, and polymer modifier
<bullet> TR 546: Sodium Dichromate Dihydrate (CASNR 7789-12-0)
    [cir] Inorganic compound containing hexavalent chromium. Used as a 
corrosion inhibitor, in the production of pigments, in electroplating, 
leather tanning, wood preservation, and textile manufacturing. Found as 
a contaminant in drinking water supplies

 [FR Doc. E7-3701 Filed 3-1-07; 8:45 am]
BILLING CODE 4140-01-P


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