### Evidence Report/Technology Assessment Number 17

# Management of AcneVolume 1: Evidence Report and AppendixesVolume 2: Evidence Tables and Bibliography

## File Inventory

Prepared by:

**File Name	Description			Software		Version		File	Size**__________________________________________________________________________________________________________01v1frnt.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		38KB	9 pagesContents: Volume 1. Evidence Report and Appendixes: Title Page, Preface, Abstract, Table of Contents__________________________________________________________________________________________________________02v1summ.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		23KB	4 pagesContents: Summary: Overview, Reporting the Evidence, Methodology, Findings, Future Research__________________________________________________________________________________________________________03v1chp1.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		34KB	8 pagesContents: Chapter 1. Introduction: Epidemiology, Disease Biology and Natural History, Burden of Illness: Morbidity and Mortality, Psychological Impact and Quality of Life,Medical Costs, Treatment of Acne, Uses of This Report__________________________________________________________________________________________________________04v1chp2.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		3.8MB	9 pagesContents: Chapter 2. Methodology: Recruitment of  Technical Experts, Patient Population, Questions, Causal Pathway, Literature Search Methods, Article Review, Peer Review__________________________________________________________________________________________________________05v1chp3.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		278KB	14 pagesContents: Chapter 3. Results: Summary of  Literature: Literature Search and Abstract Review, Article Review, Description of the Acne Literature__________________________________________________________________________________________________________06v1chp4.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		535KB	80 pagesContents: Chapter 4. Results: Evidence: Summary of Evidence; Summaries of Treatment Classes: A. Cleansers, B. Keratolytic (topical), C. Anti-bacterial (topical),  D. Anti-bacterial (topical)/Keratolytic (topical) Combinations, E. Retinoid (topical),  F. Retinoid (topical)/Keratolytic, G. Retinoid (topical)/Anti-bacterial (topical),   H. Anti-bacterial (oral), I. Anti-bacterial (oral)/Keratolytic (topical),   J. Anti-bacterial (oral)/Retinoid (topical), K. Retinoid (oral), L. Retinoid (oral)/Keratolytic,   M. Anti-androgen, N. Other;Psychological Outcomes; Compliance__________________________________________________________________________________________________________07v1chp5.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		63KB	8 pagesContents: Chapter 5. Conclusions: Characteristics of the Acne Clinical Research Literature, Overarching Conclusions, Answers to Specific Questions, Limitations__________________________________________________________________________________________________________08v1chp6.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		19KB	3 pagesContents: Future Research__________________________________________________________________________________________________________09v1refs.doc	Microsoft Word� Document	MS Word�			97 SR-1	90KB	15 pagesContents: References__________________________________________________________________________________________________________10v1appa.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		14KB	4 pagesContents: Appendix A. Technical Experts and Peer Reviewers__________________________________________________________________________________________________________11v1appb.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		34KB	4 pagesContents: Appendix B. Study Questions: Refinement by Experts__________________________________________________________________________________________________________12v1appc.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		10KB	2 pagesContents: Appendix C. Study Questions__________________________________________________________________________________________________________13v1appd.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		18KB	2 pagesContents: Appendix D. Study Questions: Expert Feedback__________________________________________________________________________________________________________14v1appe.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		7KB	2 pagesContents: Appendix E. Search Terms and Strategies__________________________________________________________________________________________________________15v1appf.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		11KB	2 pagesContents: Appendix F. Abstract Form__________________________________________________________________________________________________________16v1apg1.doc	Microsoft Word� Document	MS Word�		97 SR-1		78KB	8 pagesContents: Appendix G. Article Review Forms: Article Form__________________________________________________________________________________________________________17v1apg2.doc	Microsoft Word� Document	MS Word�		97 SR-1		53KB	6 pagesContents: Appendix G. Article Review Forms: Arm Form__________________________________________________________________________________________________________18v1apg3.doc	Microsoft Word� Document	MS Word�		97 SR-1		36KB	2 pagesContents: Appendix G. Article Review Forms: Outcome Form__________________________________________________________________________________________________________19v1apph.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		119KB	28 pagesContents: Appendix H. Included and Excluded Trials__________________________________________________________________________________________________________20v2frnt.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		18KB	5 pagesContents: Volume 2. Evidence Tables and Bibliography: Title Page, Table of Contents__________________________________________________________________________________________________________21v2desc.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		25KB	5 pagesContents: Description of the Evidence Tables: Summary Information, Presentation of Two- and Three-Arm vs. Multi-Arm Trials__________________________________________________________________________________________________________22v2indx.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		127KB	12 pagesContents: Index to Evidence Tables__________________________________________________________________________________________________________23etsumm.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		182KB	68 pagesContents: Summary Evidence Table. Trials included in the article review__________________________________________________________________________________________________________24eta1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		6KB	1 pageContents: Evidence Table A.1. Articles/arms for class Cleanser (topical)__________________________________________________________________________________________________________25eta2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		15KB	1 pageContents: Evidence Table A.2. Continuous outcomes for class Cleanser (topical)__________________________________________________________________________________________________________26eta3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		14KB	1 pageContents: Evidence Table A.3. Discrete outcomes for class Cleanser (topical)__________________________________________________________________________________________________________27etb1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		12KB	2 pagesContents: Evidence Table B.1. Articles/arms for class Keratolytic (topical)__________________________________________________________________________________________________________28etb2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		25KB	4 pagesContents: Evidence Table B.2. Continuous outcomes for class Keratolytic (topical)__________________________________________________________________________________________________________29etb3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		21KB	3 pagesContents: Evidence Table B.3. Discrete outcomes for class Keratolytic (topical)__________________________________________________________________________________________________________30etc1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		19KB	5 pagesContents: Evidence Table C.1. Articles/arms for class Anti-bacterial (topical)__________________________________________________________________________________________________________31etc2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		69KB	21 pagesContents: Evidence Table C.2. Continuous outcomes for class Anti-bacterial (topical)__________________________________________________________________________________________________________32etc3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		30KB	7 pagesContents: Evidence Table C.3. Discrete outcomes for class Anti-bacterial (topical)__________________________________________________________________________________________________________33etd1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		16KB	4 pagesContents: Evidence Table D.1. Articles/arms for class Anti-bacterial (topical)/Keratolytic (topical)__________________________________________________________________________________________________________34etd2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		34KB	7 pagesContents: Evidence Table D.2. Continuous outcomes for class Anti-bacterial (topical)/Keratolytic (topical)__________________________________________________________________________________________________________35etd3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		24KB	4 pagesContents: Evidence Table D.3. Discrete outcomes for class Anti-bacterial (topical)/Keratolytic (topical)__________________________________________________________________________________________________________36ete1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		20KB	5 pagesContents: Evidence Table E.1. Articles/arms for class Retinoid (topical)__________________________________________________________________________________________________________37ete2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		63KB	18 pagesContents: Evidence Table E.2. Continuous outcomes for class Retinoid (topical)__________________________________________________________________________________________________________38ete3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		49KB	15 pagesContents: Evidence Table E.3. Discrete outcomes for class Retinoid (topical)__________________________________________________________________________________________________________39etg1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		9KB	1 pageContents: Evidence Table G.1. Articles/arms for class Anti-bacterial/Retinoid (topical)G.2. Continuous outcomes for class Anti-bacterial/Retinoid (topical)__________________________________________________________________________________________________________40etg2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		19KB	2 pagesContents: Evidence Table G.2. Continuous outcomes for class Anti-bacterial/Retinoid (topical)__________________________________________________________________________________________________________41eth1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		27KB	7 pagesContents: Evidence Table Evidence Table H.1. Articles/arms for class Anti-bacterial (oral)__________________________________________________________________________________________________________42eth2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		56KB	15 pagesContents: Evidence Table H.2. Continuous outcomes for class Anti-bacterial (oral)__________________________________________________________________________________________________________43eth3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		50KB	14 pagesContents: Evidence Table H.3. Discrete outcomes for class Anti-bacterial (oral)__________________________________________________________________________________________________________44eti1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		6KB	1 pageContents: Evidence Table I.1. Articles/arms for class Anti-bacterial (oral)/Keratolytic (topical)__________________________________________________________________________________________________________45eti2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		17KB	2 pagesContents: Evidence Table I.2. Continuous outcomes for class Anti-bacterial (oral)/Keratolytic (topical)__________________________________________________________________________________________________________46etj1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		6KB	1 pageContents: Evidence Table J.1. Articles/arms for class Anti-bacterial (oral)/Retinoid (topical)__________________________________________________________________________________________________________47etj2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		16KB	2 pagesContents: Evidence Table J.2. Continuous outcomes for class Anti-bacterial (oral)/Retinoid (topical)__________________________________________________________________________________________________________48etj3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		14KB	1 pageContents: Evidence Table J.3. Discrete outcomes for class Anti-bacterial (oral)/Retinoid (topical)__________________________________________________________________________________________________________49etk1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		11KB	2 pagesContents: Evidence Table K.1. Articles/arms for class Retinoid (oral)__________________________________________________________________________________________________________50etk2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		33KB	7 pagesContents: Evidence Table K.2. Continuous outcomes for class Retinoid (oral)__________________________________________________________________________________________________________51etk3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		17KB	2 pagesContents: Evidence Table K.3. Discrete outcomes for class Retinoid (oral)__________________________________________________________________________________________________________52etm1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		17KB	4 pagesContents: Evidence Table M.1. Articles/arms for class Anti-androgen__________________________________________________________________________________________________________53etm2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		35KB	7 pagesContents: Evidence Table M.2. Continuous outcomes for class Anti-androgen__________________________________________________________________________________________________________54etm3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		29KB	7 pagesContents: Evidence Table M.3. Discrete outcomes for class Anti-androgen__________________________________________________________________________________________________________55etn1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		24KB	6 pagesContents: Evidence Table N.1. Articles/arms for class Other__________________________________________________________________________________________________________56etn2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		41KB	10 pagesContents: Evidence Table N.2. Continuous outcomes for class Other__________________________________________________________________________________________________________57etn3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		38KB	10 pagesContents: Evidence Table N.3. Discrete outcomes for class Other__________________________________________________________________________________________________________58etmul1.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		22KB	2 pagesContents: Evidence Table Multi.1. Trials with multi-arm outcomes__________________________________________________________________________________________________________59etmul2.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		146KB	10 pagesContents: Evidence Table Multi.2. Continuous outcomes of multi-arm trials__________________________________________________________________________________________________________60etmul3.pdf	Adobe Acrobat� Document		Adobe Acrobat�		3.02		117KB	11 pagesContents: Evidence Table Multi.3. Discrete outcomes of multi-arm trials__________________________________________________________________________________________________________61etabbr.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		8KB	1 pageContents: Selected Clinical Abbreviations Used in the Evidence Tables__________________________________________________________________________________________________________62biblio.wpd	Corel WordPerfect� Document	Corel WordPerfect�	6/7/8		121KB	32 pagesContents: Bibliography__________________________________________________________________________________________________________
*AHRQ Publication No. 01-E019 Current as of September 2001*
**Internet Citation:**

*Management of Acne*. File Inventory, Evidence Report/Technology Assessment Number 17. AHRQ Publication No. 01-E019, September 2001.  Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/acneinv.htm

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