<PAGE>
                                                                  EXHIBIT 10.10

                           SECURITIES PLEDGE AGREEMENT


         THIS SECURITIES PLEDGE AGREEMENT is dated this 26 day of October, 2001,
by and between HUNT FAMILY INVESTMENTS, L.L.L.P. (the "Pledgor") and BANK OF
AMERICA, N.A. (the "Pledgee").

                              W I T N E S S E T H:
                               - - - - - - - - - -

         WHEREAS, Pledgor executed that certain Pledge Agreement dated June 6,
2000 between Pledgor, as pledgor and HORIZON MEDICAL PRODUCTS, INC. (the
"Borrower") as pledgee covering the Pledged Securities to secure a Promissory
Note dated June 6, 2000 in the amount of $900,000;

         WHEREAS, Borrower has previously assigned the Pledged Securities to
Pledgee pursuant to a Pledge and Assignment of Note and Collateral dated June 6,
2000;

         WHEREAS, accordingly, Pledgee is currently the holder of the Pledged
Securities pursuant to the Pledge and Assignment of Note and Collateral from
Borrower dated June 6, 2000 as acknowledged by Pledgor in that certain Consent
to Assignment of Note and Collateral dated June 6, 2000;

         WHEREAS, Borrower has entered into a certain loan evidenced by that
certain Promissory Note dated May 26, 1998, made by Borrower to the order of
Pledgee in the principal face amount of Fifty Million Dollars ($50,000,000)
(hereinafter referred to as the "Note"), and as further evidenced by that
certain Amended and Restated Credit Agreement, dated as of May 26, 1998, (the
"Credit Agreement") as amended by the First Amendment to Amended and Restated
Credit Agreement dated as of November 11, 1998, the Second Amendment to Amended
and Restated Credit Agreement and Waiver dated as of March 31, 1999 the Third
Amendment to the Amended and Restated Credit Agreement and Waiver dated March
29, 2000 the Fourth Amendment to the Amended and Restated Credit Agreement and
Waiver dated June 6, 2000 the Fifth Amendment to the Amended and Restated Credit
Agreement and Waiver dated August 14, 2000 and by that certain Forbearance
Agreement dated March 30, 2001, as amended by that certain First Amendment to
Forbearance Agreement dated March 31, 2001 and that certain Second Amendment to
Forbearance Agreement dated October 16, 2001 (the "Loan");

         WHEREAS, Pledgor has executed and delivered to Pledgee a Limited
Guaranty of even date herewith to guaranty payment of the Note and Loan (the
"Guaranty");

         WHEREAS, as additional security for Pledgor's obligations to perform
its obligations under the Guaranty, the Pledgor agreed to execute this Agreement
and, pursuant hereto, to pledge the Pledged Securities, as defined in this
Agreement, as security for the prompt satisfaction of all of Pledgor's
obligations pursuant to the Guaranty and this Agreement;


                                      -1-
<PAGE>

         WHEREAS, accordingly, Pledgee is the holder of the Pledge Securities
pursuant to this Securities Pledge Agreement and the Pledge and Assignment of
Note and Collateral dated June 6, 2000.

         NOW, THEREFORE, in consideration of the foregoing, the parties agree as
follows:

         1.       Definitions. The term "Pledged Securities" shall mean the
securities described in Schedule I hereto, together with all certificates,
options, rights, or other distributions issued as an addition to, in
substitution or in exchange for, or on account of, any such securities, and all
proceeds of all of the foregoing, now or hereafter owned or acquired by the
Pledgor.

         2.       Agreement to Pledge.

         (a)      As security for the prompt payment of (i) any and all
liabilities, obligations or indebtedness of Pledgor under the Guaranty of the
Note with respect to the Loan, and (ii) any and all costs, expenses or amounts
owed under or with respect to any of the foregoing, or under or with respect to
this Securities Pledge Agreement, (all of the foregoing herein collectively
referred to as the "Secured Indebtedness"), the Pledgor hereby pledges,
hypothecates, assigns, transfers and delivers unto Pledgee, its successors and
assigns the Pledged Securities in form transferable for delivery, together with
all right, title, interest, powers, privileges and preferences pertaining or
incidental thereto, and grants the Pledgee a lien on and security interest
therein.

         (b)      If the Pledgor shall become entitled to receive or shall
receive, in connection with any of the Pledged Securities, any:

                  (i)      Certificate representing such Pledged Securities,
         including, but without limitation, any certificate representing a
         dividend or in connection with any increase or reduction of capital,
         reclassification, merger, consolidation, sale of assets, combination of
         shares, stock split, spin-off or split-off;

                  (ii)     Option, warrant, or right, whether as an addition to
         or in substitution or in exchange for any of the Pledged Securities, or
         otherwise;

                  (iii)    Dividend or distribution payable in property,
         including securities issued by other than the issuer of any of the
         Pledged Securities; or

                  (iv)     Extraordinary or liquidating dividends or
         distributions, then:

the Pledgor shall accept the same as the Pledgee's agent, in trust for the
Pledgee, and shall deliver them forthwith to the Pledgee in the exact form
received with, as applicable, the Pledgor's endorsement when necessary, or
appropriate stock powers duly executed in blank, to be held by the Pledgee,
subject to the terms hereof, as part of the Pledged Securities.

         (c)      At any time from and after the occurrence of a default under
the Note (an "Event of Default"), the Pledgee, at its option, may have any or
all of the Pledged Securities


                                      -2-
<PAGE>

registered in its name or that of its nominee, and the Pledgor hereby covenants
that, upon the Pledgee's request, the Pledgor will cause the issuer of the
Pledged Securities to effect such registration. From and after an Event of
Default, whether or not the Pledged Securities shall have been registered in the
name of the Pledgee or its nominee, the Pledgee or its nominee shall have with
respect to the Pledged Securities the right to exercise all voting rights and
all other corporate rights and all conversion, exchange, subscription or other
rights, privileges or options pertaining thereto as if he were the absolute
owner thereof, including, without limitation, the right to exchange any or all
of the Pledged Securities upon the merger, consolidation, reorganization,
recapitalization or other readjustment of the issuer thereof, or upon the
exercise by such issuer of any right, privilege, or option pertaining to any of
the Pledged Securities, and, in connection therewith, to deliver any of the
Pledged Securities to any committee, depository, transfer agent, registrar or
other designated agency upon such terms and conditions as he may determine, all
without liability except to account for property actually received by it; but
the Pledgee shall have no duty to exercise any of the aforesaid rights,
privileges or options and shall not be responsible for any failure to do so or
delay in so doing.

         (d)      Upon the occurrence of an Event of Default, the Pledgee may,
without demand of performance or other demand, advertisement, or notice of any
kind (except the notice specified below of time and place of public or private
sale) to or upon the Pledgor or any other person (all of which are, to the
extent permitted by law, hereby expressly waived), forthwith realize upon the
Pledged Securities or any part thereof, and may forthwith, or agree to, retain
the Pledged Securities in satisfaction of the Secured Indebtedness, or sell or
otherwise dispose of and deliver the Pledged Securities or any part thereof or
interest therein, in one or more parcels at public or private sale or sales, at
any exchange, broker's board or at any of the Pledgee's offices or elsewhere, at
such prices and on such terms (including, but without limitation, a requirement
that any purchaser of all of any part of the Pledged Securities purchase the
shares constituting the Pledged Securities for investment and without any
intention to make a distribution thereof) as he may deem best, for cash or on
credit, or for future delivery without assumption of any credit risk, with the
right to the Pledgee or any purchaser to purchase upon any such sale the whole
or any part of the Pledged Securities free of any right or equity of redemption
in the Pledgor, which right or equity is hereby expressly waived and released.

         (e)      The proceeds of any such disposition or other action by the
Pledgee shall be applied as follows:

                  (i)      First, to the costs and expenses incurred in
         connection therewith or incidental thereto or to the care or
         safekeeping of any of the Pledged Securities or in any way relating to
         the rights of the Pledgee hereunder, including reasonable attorneys'
         fees and legal expenses;

                  (ii)     Second, to the repayment of the Secured Indebtedness;

                  (iii)    Third, to the payment of any other amounts required
         by applicable law; and

                  (iv)     Fourth, to the Pledgor to the extent of any surplus
         proceeds.


                                      -3-
<PAGE>

         (f)      The Pledgee need not give more than five (5) days' notice of
the time and place of any public sale or of the time after which a private sale
may take place, which notice the Pledgor hereby deems reasonable.

         (g)      The Pledgee shall have the right, for and in the name, place
and stead of the Pledgor, and the Pledgor hereby grants Pledgee power of
attorney, as set forth in Section 7, to execute endorsements, assignments or
other instruments of conveyance or transfer with respect to all or any of the
Pledged Securities.

         (h)      The Pledgor recognizes that the Pledgee may be unable to
effect a public sale of all or a part of the Pledged Securities and may be
compelled to resort to one or more private sales to a restricted group of
purchasers who will be obligated to agree, among other things, to acquire the
Pledged Securities for their own account, for investment and not with a view to
the distribution or resale thereof. The Pledgor acknowledges that any such
private sales may be at prices and on terms less favorable to the Pledgee than
those of public sales, and agrees that such private sales shall be deemed to
have been made in a commercially reasonable manner and that the Pledgee has no
obligation to delay sale of any Pledged Securities to permit the issuer thereof
to register it for public sale under the Securities Act of 1933.

         (i)      The Pledgor and Pledgee recognize and agree that the Pledged
Securities have been previously pledged to Pledgee pursuant to a Pledge and
Assignment of Note and Collateral Agreement dated June 6, 2000 by and between
Borrower and Pledgee. Pledgee is currently holding the Pledged Securities and
Pledgee shall continue to hold the Pledged Securities as collateral and security
unless and until the Indebtedness as defined in the Pledge and Assignment of
Note and Collateral Agreement dated June 6, 2000 by and between Borrower and
Pledgee is fully paid and satisfied and the Secured Indebtedness is fully paid
and satisfied.

         3.       Pledgor's Warranties and Representations. The Pledgor
represents and warrants that:

         (a)      It has, and has duly exercised, all requisite power and
authority to enter into this Agreement, to pledge the Pledged Securities for the
purposes described in Section 2(a), and to carry out the transactions
contemplated by this Agreement;

         (b)      It is the legal and beneficial owner of all of the Pledged
Securities;

         (c)      All of the Pledged Securities are owned by the Pledgor free of
any pledge, mortgage, hypothecation, lien, charge, encumbrance or security
interest in such securities or the proceeds thereof, except for that granted
hereunder and the prior pledge to Borrower which has been assigned to Pledgee;
and

         (d)      Upon delivery of the Pledged Securities to the Pledgee or its
agent, this Agreement shall create a valid first lien upon and perfected
security interest in the Pledged Securities and the proceeds thereof, subject to
no prior security interest, lien, charge or


                                      -4-
<PAGE>

encumbrance, or agreement purporting to grant to any third party a security
interest in the property or assets of the Pledgor which would include the
Pledged Securities.

         4.       Pledgor's Covenants.

         (a)      The Pledgor hereby covenants that, until the Secured
Indebtedness has been repaid in full and the Note cancelled, he will not sell,
convey, or otherwise dispose of any of the Pledged Securities or any interest
therein or create, incur, or permit to exist any pledge, mortgage, lien, charge,
encumbrance or any security interest whatsoever in or with respect to any
Pledged Securities or the proceeds thereof, other than created hereby.

         (b)      The Pledgor warrants and will, at his own expense, defend the
Pledgee's right, title, special property and security interest in and to the
Pledged Securities against the claims of any person, firm, corporation or other
entity.

         5.       Notices in Regard of Pledged Securities. The Pledgor will
promptly deliver to the Pledgee all written notices, and will promptly give the
Pledgee written notice of any other notices, received by him with respect to
Pledged Securities, and the Pledgee will promptly give like notice to the
Pledgor of any such notices received by him or his nominee.

         6.       Agreement to Execute Further Documents. The Pledgor shall at
any time, and from time to time, upon the written request of the Pledgee,
execute and deliver such further documents and do such further acts and things
as the Pledgee may reasonably request to effect the purposes of this Agreement,
including, without limitation, delivering to the Pledgee upon the occurrence of
an Event of Default irrevocable proxies with respect to the Pledged Securities
in form satisfactory to the Pledgee. Until receipt thereof, this Agreement shall
constitute the Pledgor's proxy to the Pledgee or his nominee to vote all of the
Pledged Securities then registered in the Pledgor's name.

         7.       Power of Attorney. From and after an Event of Default, the
Pledgor hereby appoints the Pledgee as the Pledgor's attorney-in-fact for the
purpose of carrying out the provisions of this Agreement and taking any action
and executing any instrument which either may deem necessary or advisable to
accomplish the purposes hereof. Without limiting the generality of the
foregoing, the Pledgee shall have the right and power to receive, endorse and
collect all checks and other orders for the payment of money made payable to the
Pledgor representing any interest or dividend or other distribution payable in
respect of the Pledged Securities or any part thereof and to give full discharge
for the same.

         8.       Return of Pledged Securities. Pledgor acknowledges and agrees
that the Pledged Securities have been previously assigned to Pledgee pursuant to
a Pledge and Assignment of Note and Collateral between Borrower and Pledgee
dated June 6, 2000. Accordingly, Pledgee is currently holding the Pledged
Securities and Pledgee shall continue to hold the Pledged Securities as
collateral and security unless and until the Indebtedness as defined in the
Pledge and Assignment of Note and Collateral Agreement dated June 6, 2000 by and
between Borrower and Pledgee is fully paid and satisfied and the Secured
Indebtedness is fully paid and satisfied. Upon the repayment in full of all of
the Indebtedness as defined in the Pledge


                                      -5-
<PAGE>

and Assignment of Note and Collateral Agreement dated June 6, 2000 by and
between Borrower and Pledgee, the Secured Indebtedness and the satisfaction of
all additional costs and expenses of the Pledgee as provided herein, this
Agreement shall terminate and the Pledgee shall deliver to the Pledgor, at the
Pledgor's expense, such of the Pledged Securities as shall not have been sold or
otherwise applied pursuant to this Agreement.

         9.       General.

         (a)      Beyond the exercise of reasonable care to assure the safe
custody of the Pledged Securities while held hereunder, the Pledgee shall have
no duty or liability to preserve rights pertaining thereto and shall be relieved
of all responsibility for the Pledged Securities upon surrendering it or them or
tendering surrender of it or them to the Pledgor.

         (b)      No course of dealing between the Pledgor and the Pledgee, nor
any failure to exercise, nor any delay in exercising, any right, power or
privilege of the Pledgee hereunder shall operate as a waiver thereof; nor shall
any single or partial exercise of any right, power or privilege hereunder or
thereunder preclude any other or further exercise thereof or the exercise of any
other right, power or privilege.

         (c)      The rights and remedies provided herein are cumulative and are
in addition to and not exclusive of any rights or remedies provided by law,
including, but without limitation, the rights and remedies of a secured party
under the Uniform Commercial Code.

         (d)      The provisions of this Agreement are severable, and if any
clause or provision shall be held invalid or unenforceable in whole or in part
in any jurisdiction, then such invalidity or unenforceability shall affect only
such clause or provision or part thereof in such jurisdiction and shall not in
any manner affect such clause or provision in any other jurisdiction or any
other clause or provision in this Agreement in any jurisdiction.

         (e)      Any notice required or permitted by this Securities Pledge
Agreement shall be effective if mailed, postage prepaid, by registered or
certified mail, return receipt requested, or if delivered to the Pledgor or
Pledgee at their addresses specified below, or at such other addresses as the
Pledgor or the Pledgee may theretofore have designated in writing and given in
like manner to the other.

         (f)      This Agreement shall inure to the benefit of and shall be
binding upon the successors and assigns of the parties hereto.

         (g)      This Agreement shall be construed in accordance with the
substantive law of the State of Georgia without regard to principles of
conflicts of law and is intended to take effect as an instrument under seal.

         IN WITNESS WHEREOF, the parties hereto have duly executed this
Agreement as of the date and year first above written.


                                      -6-
<PAGE>

Signed, sealed, sworn to and delivered
in the presence of:                        PLEDGOR:

                                           HUNT FAMILY INVESTMENTS,
------------------------------------       L.L.L.P.
Witness

                                            By:
                                               --------------------------------
------------------------------------           Name:  Marshall B. Hunt
Notary Public                                  Title:  Managing General Partner

Notarized this 26th day of October, 2001.      Address:

My commission expires:                         3935 Paces Manor
                                               Atlanta, Georgia 30339
         (NOTARIAL SEAL)


Signed, sealed, sworn to and delivered
in the presence of:                        PLEDGEE:
                                           BANK OF AMERICA, N.A.
-------------------------------------
Witness
                                              By:
                                                 ------------------------------
                                                 Name:
                                                      -------------------------
-------------------------------------            Title:
Notary Public                                          ------------------------


Notarized this ______ day of October, 2001.
                                                Address:
My commission expires:
                                                101 North Tryon Street
         (NOTARIAL SEAL)                        NC1-001-13-26
                                                Charlotte, North Carolina 28255


                                      -7-
<PAGE>
                                                                   EXHIBIT 10.11
                                   SCHEDULE I

<TABLE>
<CAPTION>

                                                     Number and Description
                                                               of
Issuer                                                  Pledged Securities                                Name of Holder
<S>                                                  <C>                                      <C>

Horizon Medical Products, Inc.                       924,210 Shares of Class A                Hunt Family Investments, L.L.L.P.
                                                           Common Stock

</TABLE>


                                      -8-
<PAGE>

                    POWER OF ATTORNEY TO TRANSFER SECURITIES

         FOR VALUE RECEIVED, the undersigned, Hunt Family Investments, L.L.L.P.
hereby sells, assigns and transfers to _________________________________,
924,210 shares of capital stock, Certificate No. 72, standing in his name on the
books of Horizon Medical Products, Inc. and does hereby irrevocably constitute
and appoint any officer or transfer agent of the corporation the power of
attorney to transfer all said shares on the books of the within named
corporation with full power of substitution.


Signed, sealed, sworn to and
delivered in the presence of:                  HUNT FAMILY INVESTMENTS,
                                               L.L.L.P.
---------------------------------
Witness                                        By:
                                                   ----------------------------
                                               Name:  Marshall B. Hunt
---------------------------------              Title:  Managing General Partner
Notary Public

Notarized this 26th day of
October, 2001.

My commission expires:


         (NOTARIAL SEAL)


              [Signature Guaranty]


                                      -9-