8392 Federal Register / Vol. 72, No. 37 / Monday, February 26, 2007 / Notices 

patent license to practice the inventions 

embodied in U.S. Patent 6,756,038 and 

PCT Application Serial No. PCT/US98/ 

19794 and foreign equivalents thereof, 

entitled ‘‘Agonist and Antagonist 

Peptides of Carcinoembryonic Antigen 

(CEA)’’ (E–099–1996/0) and U.S. Patent 

6,969,582 and PCT Application Serial 

No. PCT/US99/26866 and foreign 

equivalents thereof, entitled ‘‘A 

Recombinant Vector Expressing 

Multiple Costimulatory Molecules and 

Uses Thereof’’ (E–256–1998/0), to 

GlobeImmune Inc., which is located in 

Louisville, Colorado. The patent rights 

in these inventions have been assigned 

to the United States of America. The 

prospective exclusive license territory 

may be worldwide and the field of use 

may be limited to the use recombinant 

Saccharomyces cerevisiae expressing 

CEA for the prevention and treatment of 

cancer. 

DATES: Only written comments and/or 

applications for a license which are 

received by the NIH Office of 

Technology Transfer on or before April 

27, 2007 will be considered. 

ADDRESSES: Requests for copies of the 

patent application, inquiries, comments, 

and other materials relating to the 

contemplated exclusive license should 

be directed to: Michelle A. Booden, 

PhD., Technology Licensing Specialist, 

Office of Technology Transfer, National 

Institutes of Health, 6011 Executive 

Boulevard, Suite 325, Rockville, MD 

20852–3804; Telephone: (301) 451–

7337; Facsimile: (301) 402–0220; E-mail: 

boodenm@mail.nih.gov. 

SUPPLEMENTARY INFORMATION: The 

technology describes the composition 

and use of nucleic acid sequences that 

encode agonist and one antagonist 

peptide variants of the human 

carcinoembryonic antigen (CEA) 

peptide, including but not limited to 

CAP–1. CEA is an antigen, which is 

expressed on the surface of various 

types of cancer cells. It is capable of 

stimulating a specific cytolytic T cell 

response, as is CAP–1, which is a highly 

immunogenic epitope of CEA. 

Therefore, CAP–1 agonists which are 

capable of eliciting a CEA-specific 

cytolytic T cell response, such as those 

identified by the inventors, may 

represent potential immunogens for use 

as therapeutic agents or vaccines against 

various cancers, and possibly also for 

use against autoimmune diseases. In 

fact, at least one of the agonist peptides 

appears to be more immunogenic than 

the native CAP–1 peptide. CAP–1 

antagonists which are capable of 

reducing or eliminating this T cell 

response, such as the antagonist peptide 

variant identified by the inventors, may 

represent potential agents for use 

against autoimmune responses to CEA 

or to agonist peptide variants thereof. 

The prospective exclusive license will 

be royalty bearing and will comply with 

the terms and conditions of 35 U.S.C. 

209 and 37 CFR Part 404.7. The 

prospective exclusive license may be 

granted unless within sixty (60) days 

from the date of this published notice, 

the NIH receives written evidence and 

argument that establishes that the grant 

of the license would not be consistent 

with the requirements of 35 U.S.C. 209 

and 37 CFR Part 404.7. 

Applications for a license in the field 

of use filed in response to this notice 

will be treated as objections to the grant 

of the contemplated exclusive license. 

Comments and objections submitted to 

this notice will not be made available 

for public inspection and, to the extent 

permitted by law, will not be released 

under the Freedom of Information Act, 

5 U.S.C. 552. 

Dated: February 16, 2007. 

Steven M. Ferguson, 

Director, Division of Technology Development 

and Transfer, Office of Technology Transfer, 

National Institutes of Health. 

[FR Doc. E7–3153 Filed 2–23–07; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

National Institute of General Medical 

Sciences 2008–2012 Strategic Plan 

ACTION: Notice with request for 

comments. 

SUMMARY: NIGMS is initiating a strategic 

planning process that will culminate in 

the NIGMS Strategic Plan for 2008–

2012. To assist with this process, 

NIGMS requests input from scientists, 

scientific organizations, and other 

interested parties. The goal of this 

strategic planning process is to identify 

Institute priorities and guide decisionmaking over the next five years. 

Information about NIGMS can be found 

at http://www.nigms.nih.gov/. 

DATES: In order to ensure full 

consideration, responses must be 

submitted by 12 midnight EDT on 

March 20, 2007. 

ADDRESSES: Interested individuals and 

organizations should submit their 

responses to http://www.nigms.nih.gov/ 

About/StrategicPlan/Input.htm. 

SUPPLEMENTARY INFORMATION: 

Background 

The mission of the National Institute 

of General Medical Sciences (NIGMS) is 

to support basic research whose results 

lay the foundation for the diagnosis, 

treatment, and prevention of disease. 

NIGMS-funded researchers seek to 

answer important questions in fields 

such as cell biology, biophysics, 

genetics, developmental biology, 

pharmacology, physiology, 

biochemistry, chemistry, bioinformatics, 

and computational biology, and in 

selected cross-cutting clinical areas that 

affect multiple organ systems. NIGMS 

also provides leadership in promoting 

the diversity of the scientific workforce 

and in training the next generation of 

scientists to assure the vitality and 

continued productivity of basic 

research. 

NIGMS has embarked on a strategic 

planning process to identify Institute 

priorities to guide decision-making over 

the next five years. To assure the 

broadest possible input, NIGMS is 

inviting the scientists, scientific 

organizations, and other interested 

parties to respond electronically to a 

series of questions, listed below. 

• What factors should NIGMS 

consider in deciding how to set its 

priorities with respect to new and 

existing areas of support? 

• What factors should NIGMS 

consider in deciding how to set its 

priorities with respect to research 

training? 

• What new or emerging areas, 

approaches, or technologies in basic 

biomedical research should NIGMS 

pursue? 

• As part of its efforts to maintain a 

balanced research portfolio, how can 

NIGMS best encourage and support 

research that is highly innovative and/ 

or risky? 

• Are there areas of current NIGMS 

research activity that should receive less 

emphasis? 

• How can NIGMS enhance its 

communication with the scientific 

community and the public? 

• How can NIGMS more effectively 

promote and encourage greater diversity 

in the biomedical research workforce? 

You may also submit other comments 

relevant to NIGMS that are not 

specifically addressed in these 

questions. 

Responses will be limited to 

approximately 500 words per question. 

All information provided will be 

processed and analyzed with strict 

anonymity. 

Contact Person: Judith H. Greenberg, 

PhD., National Institute of General 

Medical Sciences, National Institutes of 


ycherry on PROD1PC64 with NOTICES
Federal Register / Vol. 72, No. 37 / Monday, February 26, 2007 / Notices 8393 

Health, Building 45, Room 2AS25, 45 

Center Drive, MSC 6200, Bethesda, 

Maryland 20892–6200; 301–594–0943; 

greenbej@nigms.nih.gov. 

Dated: February 16, 2007. 

Jeremy M. Berg, 

Director, National Institute of General 

Medical Sciences, National Institutes of 

Health. 

[FR Doc. E7–3152 Filed 2–23–07; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF THE INTERIOR 

Fish and Wildlife Service 

Notice of Availability of an 

Environmental Assessment and 

Receipt of an Application for 

Amendment to an Incidental Take 

Permit for the Green Diamond 

Resource Company Habitat 

Conservation Plan for the Northern 

Spotted Owl, Del Norte and Humboldt 

Counties, CA 

AGENCY: Fish and Wildlife Service, 

Interior. 

ACTION: Notice of availability and 

receipt of application. 

SUMMARY: Green Diamond Resource 

Company (Green Diamond) (previously 

Simpson Timber Company) has applied 

to the Fish and Wildlife Service 

(Service) to amend its existing 

incidental take permit (ITP) for the 

federally threatened northern spotted 

owl (Strix occidentalis caurina; ‘‘NSO’’). 

The existing ITP was issued in 1992, in 

association with a Habitat Conservation 

Plan (Plan) and Implementation 

Agreement (IA), pursuant to section 

10(a)(1)(B) of the Endangered Species 

Act (Act) of 1973, as amended. 

The proposed ITP amendment would 

authorize the take of eight additional 

owl pairs on Green Diamond’s 

ownership in Humboldt and Del Norte 

counties, California. These additional 

takes would be authorized during the 

existing permit term expiring in 2022, 

and would provide Green Diamond 

operational flexibility while they and 

the Service further consider and 

evaluate the findings of a 10-year, 

comprehensive Plan review. 

The application for permit 

amendment includes proposed 

amendments to the existing IA and Plan, 

which describe the proposed action and 

the measures that Green Diamond will 

undertake to minimize and mitigate take 

of the NSO. 

DATES: Written comments must be 

received on or before April 27, 2007. 

ADDRESSES: Send written comments to 

Ms. Amedee Brickey, ES Program 

Manager, U.S. Fish and Wildlife 

Service, 1655 Heindon Road, Arcata, 

California 95521. You also may send 

comments by facsimile to 707–822–

8411. 

FOR FURTHER INFORMATION CONTACT: Mr. 

Gary Falxa, [see ADDRESSES] or call 707–

822–7201. 

SUPPLEMENTARY INFORMATION: 

Availability of Documents 

You may obtain copies of these 

documents for review by contacting the 

above office. Documents also will be 

available for public inspection, by 

appointment, during normal business 

hours at the Arcata Fish and Wildlife 

Office [see ADDRESSES] and at each of 

the following libraries: 

(1) Eureka Main Library, 1313 3rd 

Street, Eureka, CA; telephone: 707–269–

1900. 

(2) Fortuna Branch, Humboldt County 

Library, 775 14th Street, Fortuna, CA; 

telephone: 707–725–3460. 

(3) Arcata Branch, Humboldt County 

Library, 500 7th Street, Arcata, CA; 

telephone: 707–822–5924. 

(4) Del Norte County Library, 190 

Price Mall, Crescent City, CA; 

telephone: 707–464–9793. 

Background 

Section 9 of the Act and Federal 

regulations prohibit the ‘‘take’’ of fish 

and wildlife species listed as 

endangered or threatened. Take of 

federally listed fish and wildlife is 

defined under the Act to include 

‘‘harass, harm, pursue, hunt, shoot, 

wound, kill, trap, capture, or collect, or 

to attempt to engage in any such 

conduct.’’ The Service may, under 

limited circumstances, issue permits to 

authorize incidental take (i.e., take that 

is incidental to, and not the purpose of, 

the carrying out of an otherwise lawful 

activity). Regulations governing 

incidental take permits for threatened 

and endangered species are found in 50 

CFR 17.32 and 17.22. 

On September 17, 1992, the Service 

issued an ITP to the Applicant 

authorizing take of up to 50 NSO pairs 

in accordance with conditions set forth 

in the Plan and an IA. The ITP was 

issued in response to a permit 

application with an associated Habitat 

Conservation Plan for timber harvesting 

on the firm’s properties in Del Norte, 

Humboldt, Mendocino, and Trinity 

counties, California. The effects of the 

proposed ITP were analyzed and 

described in an Environmental 

Assessment (EA) prepared and issued 

by the Service (Notice of Availability, 

Federal Register, May 27, 1992). 

Green Diamond is proposing to 

amend its ITP to authorize take of up to 

eight additional NSO pairs on that part 

of its ownership, currently about 

416,533 acres, on the west slopes of the 

Klamath Mountains and the Coast Range 

in Humboldt and Del Norte counties, 

California. The Applicant anticipates 

that these takes would be in the form of 

displacement of NSO pairs, incidental 

to timber harvest activities in or near 

NSO nest sites or activity centers. 

To mitigate take of eight additional 

owl pairs, Green Diamond proposes, in 

addition to measures in the existing 

Plan, to conduct new research on the 

habitat overlap and interaction between 

the NSO and barred owl (Strix varia), 

and to re-establish, through year 2012, 

a special management area of about 

20,310 acres on its ownership, within 

which Green Diamond would not take 

owls. 

The Service’s EA considers the 

environmental consequences of three 

alternatives, including: (1) The 

Proposed Project Alternative, which 

consists of issuance of an amended ITP 

and implementation of the additional 

Plan measures; (2) an alternative that 

provides for the take of eight additional 

owl pairs (similar to the Proposed 

Action), plus release for harvest entry of 

three set-aside areas that are otherwise 

not available for timber harvest during 

the term of the ITP; and (3) the No 

Action Alternative, which provides for 

continued implementation of measures 

contained in the existing Plan and 

associated IA, and the level of 

incidental take authorized in the 

existing 1992 ITP. 

National Environmental Policy Act 

Proposed permit issuance triggers the 

need for compliance with the National 

Environmental Policy Act (NEPA). 

Accordingly, as the NEPA lead agency, 

the Service is providing this notice of 

the availability and is making the EA 

available for public review. 

Public Review 

The Service invites the public to 

review the EA and amendments to the 

Plan and IA during a 60-day public 

comment period [see DATES]. Written 

comments from interested parties are 

welcome to ensure that the issues of 

public concern related to the proposed 

action are identified. Comments and 

materials received will be available for 

public inspection, by appointment, 

during normal business hours at the 

office listed in the ADDRESSES section of 

this notice. All materials received will 

become part of the administrative 

record. Our practice is to make 

comments, including names, home 

addresses, home phone numbers, and 

email addresses of respondents, 


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