## Cover Letter

[The PMN substance is an intermediate used to manufacture another intermediate that will ulimately be used to manufacture a FIFRA registered pesticide. Manufacture of the PMN substance occurs at one site and use to make the penultimate intermediate occurs at another site both controlled by the submitter. The PMN substance is consumed in the manufacture of the penultimate intermediate which will be the subject of a subsequent PMN. We conducted the environmental portion of the Sustainable Futures Assessment concluding that the substance is moderately toxic but there is no risk from the activities described in the PMN. QSAR and Read-Across data are provided as attachments.]

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### 25I0327L 456_141016476901699 DO497W

X X X

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## X

2-Pyridinecarboxylic acid, 4,5,6-trichloro496849-77-5 

## X 383351 IES Public.pdf 

### C6 H2 Cl3 N O2 See Attachment 002 (Structure Public.pdf)

Structure Public.pdf Page 5 SANITIZED SUBMISSIONXXX

The manufacturing process to produce the PMN substance consists of a hydrolysis reaction followed by precipitation, filtration and drying. The hydrolysis reaction and precipitation steps are done in the same vessel.

85-95% 

## X

Reaction Public.pdf

Page 6 SANITIZED SUBMISSIONPage 7 SANITIZED SUBMISSIONPage 8 SANITIZED SUBMISSION4,5,6-Trichloropyridine-2-carboxylic Acid, 4,5,6-Acid

4,5,6-Trichloropyridine-2-carboxylic acid Water 7732-18-5 12 XXX XXX XXX 

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X Chemical intermediate XXX 

### X 100 90 0 0 100 0

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XXX XXX XXX 

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X 1

XXX 

## X XXX XXX XXX XXX XXX 

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Page 11 SANITIZED SUBMISSIONSee Attachment 004 (Manufacture Public.pdf)

Manufacture Public.pdf Page 12 SANITIZED SUBMISSIONFilling product in Super

Sacks ( 2 sacks per batch) See continuation page. id: <P9SA2(3)C1R1> Solid wet powder ~90% 2 XXX XXX 

### X X Sampling dryer during filling super sacks. (2 samples per batch) See continuation page. id: <P9SA2(3)C1R2> Solid wet powder ~90% 1 0.05 39 

### X Mother liqour sampling tank after neutralization See continuation page. id: <P9SA2(3)C1R3> 0.006% in water 1 0.25 39 

### X Sample Reactor See continuation page. id: <P9SA2(3)C1R4> 76% in water 1 0.25 39 

### X

Page 13 SANITIZED SUBMISSIONP9SA2(3)C1R1 Part II, Section A, 2.(3) Prot. Equipment, etc., Row 1

PPE: Full-face APR with organic vapor/acid gas and HEPA filter cartridges, neoprene gloves, and impervious suit such as saranex or PVC suit Local ventilation system

Page 14 SANITIZED SUBMISSIONP9SA2(3)C1R2 Part II, Section A, 2.(3) Prot. Equipment, etc., Row 2

PPE: Full-face APR with organic vapor/acid gas and HEPA filter cartridges, neoprene gloves, and impervious suit such as saranex or PVC suit

Page 15 SANITIZED SUBMISSIONP9SA2(3)C1R3 Part II, Section A, 2.(3) Prot. Equipment, etc., Row 3

PPE: Full-face APR with organic vapor/acid gas and HEPA filter cartridges, neoprene gloves, and impervious suit such as saranex or PVC suit

Page 16 SANITIZED SUBMISSIONP9SA2(3)C1R4 Part II, Section A, 2.(3) Prot. Equipment, etc., Row 4

PPE: Full-face APR with organic vapor/acid gas and HEPA filter cartridges, neoprene gloves, and impervious suit such as saranex or PVC suit

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XXX 

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Page 19 SANITIZED SUBMISSIONSee Attachment 005 (Use Public.pdf)

Use Public.pdf Page 20 SANITIZED SUBMISSIONOff-loading Super sack See continuation page. id: <P9SA2(3)C2R1> Solid wet powder – ~90% (10% water) 1 XXX XXX 

### X X

Page 21 SANITIZED SUBMISSIONP9SA2(3)C2R1 Part II, Section A, 2.(3) Prot. Equipment, etc., Row 1

PPE: Full-face APR with organic vapor/acid gas and HEPA filter cartridges, neoprene gloves, and impervious suit such as saranex or PVC suit

Page 22 SANITIZED SUBMISSION1 0 On-site Incineration Incineration 0

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Page 24 SANITIZED SUBMISSIONPage 25 SANITIZED SUBMISSIONPage 26 SANITIZED SUBMISSION001 IES Report IES Public.pdf Pt.I, Sec.B, 1c. 2 002 Structure Structure Public.pdf Pt.I, Sec.B, 1e. 1 003 MSDS Public MSDS Public.pdf 4 004 Manufacture Public Manufacture Public.pdf Pt.2, Sec.A, 1d. 1 005 Use Public Use Public.pdf Pt.2, Sec.A, 1d. (#2) 1 006 NMR Sprctrum NMR Spectrum Public.pdf 1 007 Reaction Scheme Reaction Public.pdf Pt.I, Sec.B, 1e(2). 1 008 Density Public Density Public.pdf 1 009 Water Solubility Public Water Solubility Public.pdf 1 010 EpiSuite Public EPISuite_Results Public.pdf 18 011 SF Assessment Public 456Acid_SF_EnvironmentalAsse ssment Public.pdf 10 012 Read Across Public Read Across Public.pdf 2

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## X 9.82E-06 Estimate 25 1.74 Measured
150 Measured 45 acetonitrile/water 0.3 Measured 22 125 Measured 357 Estimate 760 Measured 2.96 Estimate

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## ATTACHMENT HEADER SHEET Attachment Number 001 Attachment Name IES Report 

## Associated PMN Section Number

Pt.I, Sec.B, 1c. Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 002 Attachment Name Structure 

## Associated PMN Section Number

Pt.I, Sec.B, 1e. Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 003 Attachment Name MSDS Public 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 004 Attachment Name Manufacture Public 

## Associated PMN Section Number

Pt.2, Sec.A, 1d. Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 005 Attachment Name Use Public 

## Associated PMN Section Number

Pt.2, Sec.A, 1d. (#2) Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 006 Attachment Name NMR Sprctrum 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 007 Attachment Name Reaction Scheme 

## Associated PMN Section Number

Pt.I, Sec.B, 1e(2). Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 008 Attachment Name Density Public 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 009 Attachment Name Water Solubility Public 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 010 Attachment Name EpiSuite Public 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 011 Attachment Name SF Assessment Public 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number 456_141016476901699

## ATTACHMENT HEADER SHEET Attachment Number 012 Attachment Name Read Across Public 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number 456_141016476901699