Environment Fate and Aquatic Toxicity TS01TX

Environmental Fate and Toxicity

9-Octadecen-1-amine, hydrochloride (1:1), (9Z)- (EINECS)

41130-29-4

(aka Oleylamine HCL)

Regulatory Info:

CA Index nomenclature not TSCA publicly listed but listed on EINECS, (Apparently no 

chloride data was submitted for the Primary Amine salt registrations in Europe.)

The justification for this using data on the Oleylamine is that the substance will always bind a 

counter ion at environmental pH. Existing data on the amine is being submitted to support 

the complementary amine hydrochloride.

The test substance for these studies is Armeen OD which is a purified preparation of the 

primary amine precursor of the new chemical 9-Octadecen-1-amine, hydrochloride CASRN 

112-90-3. It contains less than 1% of the as 9-Octadecen-1-amine, N-(9Z)-9-octadecen-1-yl-, 

(9Z) (CASRN 40165-86-2).which is an unintended byproduct of its production.

Aquatic for Oleylamine:

Study Type: Acute Toxicity to Fathead Minnow

Date: 09/05/95

Laboratory: Akzo Nobel Central Research Arnhem

Results: The test article was described as a yellow liquid with ammonia 

odor. Oleylamine was tested in the absence and presence of humic acid. Stock 

“dispersions” of test article were prepared in water using ultrasonic treatment. Only 

nominal concentrations of test article were reported.

LC50 (96-hour) Value Humic Acid Concentration

LC50 = 0.11 mg/l 0 mg/l

LC50 = 1.50 mg/l 10 mg/l

LC50 = 2.13 mg/l 20 mg/l

The test article was highly toxic to fathead minnow under the conditions of this test, 

in the absence of humic acid. The addition of humic acid (to simulate water sources 

in the actual environment) at a level of 10 mg/l resulted in a substantial (approximate 

10 fold) reduction in toxicity.

This study was submitted to the U.S. EPA under a TSCA Section 4 Test Rule/SIDS 

program.

Study Type: Acute Toxicity to Daphnia magna

Date: 10/24/95

Laboratory: Akzo Nobel Central Research Arnhem

Results: The test article was described as a yellow liquid with ammonia odor. Stock 

“dispersions” of test article were prepared in water using ultrasonic 

treatment. Oleylamine was tested in the absence and presence of humic 

acid. Only nominal concentrations of test article were reported.
Environment Fate and Aquatic Toxicity TS01TX

EC50 (48-hour) Value Humic Acid Concentration

EC50 = 0.011 mg/l 0 mg/l

EC50 = 0.43 mg/l 10 mg/l

EC50 = 0.56 mg/l 20 mg/l

The test article was highly toxic to Daphnia magna (water fleas) under the 

conditions of this test, in the absence and presence of humic acid. The 

addition of humic acid (to simulate water sources in the actual environment) at 

a level of 10 mg/l resulted in an approximate 40 fold reduction in toxicity.

This study was submitted to the U.S. EPA under a TSCA Section 4 Test 

Rule/SIDS program.

Study Type: Acute Algal Toxicity

Date: 10/24/95

Laboratory: Akzo Nobel Central Research Arnhem

Results: The test article was described as a yellow liquid. Oleylamine was tested in the 

absence and presence of humic acid. Stock “dispersions” of test article were 

prepared in water using ultrasonic treatment. Only nominal concentrations of 

test article were reported.

EC50 Value Humic Acid Concentration

EC50 (growth) = 0.03 mg/l 0 mg/l

EC50 (growth rate) = 0.04 mg/l 0 mg/l

EC50 (growth) = 0.23 mg/l 5 mg/l

EC50 (growth rate) = 0.37 mg/l 5 mg/l

EC50 (growth) = 0.49 mg/l 10 mg/l

EC50 (growth rate) = 0.76 mg/l 10 mg/l

The test article was highly toxic to green algae under the conditions of this 

test, with respect to both growth and growth rate. The addition of humic acid 

(to simulate water sources in the actual environment) resulted in an 

approximate 10 fold reduction in toxicity, however, even with this reduction in 

toxicity, the test article was still highly toxic to the test species.

This study was submitted to the U.S. EPA under a TSCA Section 4 Test 

Rule/SIDS program.
Environment Fate and Aquatic Toxicity TS01TX

Study Type: Biodegradation

Date: 02/28/92

Laboratory: Akzo Research Laboratories Arnhem

Results: The test article was described as a liquid. The test article was biodegraded 

44% at day 28, and 72% at day 42. Total mineralization was reported at day

42. Although the test article was not readily biodegradable by the OECD 

definition, it can be classified as inherently biodegradable. Because the test 

article was biodegraded (mineralized) up to 72%, the test article can also be 

described as ultimately biodegradable.

Conclusions: Armeen OD was ultimately biodegradable in the Closed Bottle Test.