SECTION 302 CEO CERTIFICATION
                                                                    Exhibit 31.1

                                  CERTIFICATION

I, Louis Greco, certify that:

1.   I have reviewed this annual report on Form 10 - KSB of GLOBAL BIOTECH CORP.

2.   Based on my knowledge, this report does not contain any untrue statement of
     a material fact or omit to state a material fact necessary to make the
     statements made, in light of the circumstances under which such statements
     were made, not misleading with respect to the period covered by this
     report;

3.   Based on my knowledge, the financial statements, and other financial
     information included in this report, fairly present in all material
     respects the financial condition, results of operations and cash flows of
     the small business issuer as of, and for, the periods presented in this
     report;

4.   The small business issuer's other certifying officer(s) and I are
     responsible for establishing and maintaining disclosure controls and
     procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for
     the small business issuer and have:

a)   Designed such disclosure controls and procedures, or caused such disclosure
     controls and procedures to be designed under our supervision, to ensure
     that material information relating to the small business issuer, including
     its consolidated subsidiaries, is made known to us by others within those
     entities, particularly during the period in which this report is being
     prepared;

b)   Evaluated the effectiveness of the small business issuer's disclosure
     controls and procedures and presented in this report our conclusions about
     the effectiveness of the disclosure controls and procedures, as of the end
     of the period covered by this report based on such evaluation; and

c)   Disclosed in this report any change in the small business issuer's internal
     control over financial reporting that occurred during the small business
     issuer's most recent quarter (the small business issuer's fourth quarter in
     the case of an annual report) that has materially affected, or is
     reasonably likely to materially effect the small business issuer's internal
     control over financial reporting; and

5.   The small business issuer's other certifying officer(s) and I have
     disclosed, based on our most recent evaluation of internal control over
     financial reporting, to the small business issuer's auditors and the audit
     committee of the small business issuer's board of directors (or persons
     performing the equivalent function):

     A) All significant deficiencies and material weaknesses in the design or
     operation of internal controls over financial reporting which are
     reasonably likely to adversely affect the small business issuer's ability
     to record, process, summarize and report financial information; and

     B) Any fraud, whether or not material, that involves management of other
     employees who have a significant role in the small business issuer's
     internal controls over financial reporting.


Dated: June 15, 2007
                                                              BY;/S/ Louis Greco
                                                              ------------------
                                                                     Louis Greco
                                                                       President
                                     (Principal Executive and Financial Officer)