# Position Paper on Registration Review of Silver Compounds
December 12, 2012

Abstract

The Silver Task Force North America maintains that the interests of the public, the Environmental Protection Agency, and registrants of silver-based antimicrobials would best be served by a common data call-in for all silver-based antimicrobials. The Task

Force bases its position on the rationale that all silver-based antimicrobials function by the release of silver cation as the biologically active moiety. Although there are several forms of silver-containing active ingredients under review, the active component of toxicological interest for risk assessment purposes for all EPA registered, silver based products is the silver ion.

Background

The Silver Task Force North America (STF NA or Task Force) 1 

# is composed of 32 companies that have taken an interest in silver-based antimicrobial products

. In addition to registrants of silver-based technical grade active ingredients and formulated products, the Silver Task Force North America is comprised of companies that have or are developing silver-based antimicrobial technologies as well as consulting firms with extensive experience in representing silver-based antimicrobials in the United States and around the world (See Attachment 1 for a list of STF NA members) . The common factor among this diverse group of companies is their expertise in the manufacture, use, and marketing of silver-based antimicrobials. Their common goal is to share this expertise with the U.S. Environmental Protection Agency (EPA) and work together with

the EPA to ensure that the current re-evaluation of silver-based antimicrobials addresses all relevant data gaps and concerns in a manner that best utilizes the finite

resources of both the Agency and industry.

In the fall of 2007, the EPA first met with silver registrants to discuss the registration review process for silver products

. There was recognition by industry at that time that pooling the collective knowledge of the silver registrants made eminent sense since it is the opinion of much of industry that all silver antimicrobials act via the silver ion

. An organizational meeting of the U.S. Silver Task Force was held in the summer of 2009 and the U.S. Silver Task Force held its inaugural meeting on October 14 th 

# of that year.

The first task of the group was to respond to the EPA Preliminary Work Plan for the review of silver-based antimicrobials published in June of 2009

. The Task Force identified a number of key issues

. Among these were:

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

#  Use of bridging data between the different silver actives

. Since all silver products rely on the release of silver ions to achieve their antimicrobial effect, this potentially allows for one representative test substance;

 The environmental fate of silver-based antimicrobials being governed by the chemistry of silver/silver ions; and

 Certain proposed exposure, toxicity, and environmental studies would not add to the body of knowledge but would tie up resources of both the Agency and industry that could be better directed to other issues.

Over the following thirty months the U.S. Silver Task Force, working in co-operation with the EPA, was able to show that the dermal exposure data requirements as outlined in the original draft of the Registration Review were not necessary

. The U.S. Silver Task Force also prepared a position paper on environmental fate and ecotoxicity and detailed comments on the draft Registration Review to help the EPA better understand and address key issues.

The U.S. Silver Task Force has continued to work with the Agency since the release of

the first set of Data Call- In notices (DCI) for silver-based actives issued February 29,

2012

. The U.S. Silver Task Force is already assisting the Agency in collecting data on the particle size and distribution of silver-based actives. Some of the members of the U.S. Silver Task Force that have silver zeolite products met with the Agency on April 18, 2012, to discuss the DCI. During the meeting EPA acknowledged that it is still evaluating how to finalize the categorization of silver-based products and whether to issue multiple DCIs for each of the types of silver (silver and silver salts, silver zeolites and nanosilver) or a single revised DCI that specifies which data is required for each category, which studies can be bridged between the categories, and which data are specific for each separate category.

EPA also acknowledged that from a historical perspective, the Agency has taken an inconsistent approach to the registration of the various silver products containing

various forms of silver

. However, it was agreed that the Registration Review process provides an opportunity for EPA to make consistent the approach and evaluation of all silver products

. At that meeting the U.S. Silver Task Force offered, and was pleased that the Agency welcomed, that the U.S. Silver Task Force provide recommendations in regards to this process

. The EPA and registrants will benefit from a common understanding of the various forms of silver contained in currently registered products and a categorization scheme for those silver forms that permits use of newly generated data to address hazard characterization and risk assessment needs broadly

.

In April of 2012,several members of the U.S. Silver Task Force realized the need for a more permanent organization under which corporations could generate data in response to the various silver Data Call-In Notices. In August of 2012, the Silver Task Force North America (STFNA), an unincorporated nonprofit association, was formed.

The STFNA carefully reviewed the wide variety of silver compounds covered by the Registration Review

. As a result the STF NA has prepared this position paper to demonstrate that, irrespective of the delivery method, be it silver salts, silver zeolites or

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

# silver metal, the common biologically active moiety for silver -containing antimicrobials is silver ion and that data requirements should be based on this knowledge

. Recognizing the commonality of the silver ion should motivate EPA to consolidate its DCI activities to take advantage of efficiencies and economies for both itself and registrants of silver compounds. The Task Force suggests issuing a new silver DC I for all silver-based actives based on identification of silver ion as the biologically active moiety

. This will conserve Agency and industry resources by reducing both the workload and the repetition of testing and complete the review of silver-based actives in a more timely

fashion.

Should issuing a new DCI for all silver compounds be administratively impractical or undesirable, the Task Force suggests adjusting the call-in deadlines for silver compounds to place all respondents on a common schedule

. While the Task Force recognizes that the Agency historically has distinguished silver compounds by active ingredient designation or other means of categorization, this proceeding will demonstrate that the focus should be on silver ions and that the historical categories are arbitrary (and in some cases erroneous) and no longer necessary as the Agency‟s focus

shifts to hazard and risk assessment for the silver ion.

A Rationale for Focus on Silver Ion for Risk Assessment

There are currently some 13 5 registered silver antimicrobial products

. Of these, 106 describe their active ingredient as “silver,” PC Code 072501 – that is, metallic silver,

CAS# 7440- 22 -4. These include all but one of those registered in the four decades before 1996 and the majority of those registered since. Although many of these products are identified as having metallic silver as the active ingredient, most may be more accurately described as various salts, glasses, and ion-exchange carriers of silver

in the form of silver ions

. Th ree years ago Ionic silver Ag(1+), CAS# 14701- 21 -4, received its own PC Code ,072500, and the first three products were registered under this code in late 2009. Creation of this new PC Code, apparently by the Agency on its own initiative, suggests EPA already recognizes the validity of adopting a new focus on

the silver ion.

Historically the Agency has taken the position that some silver antimicrobials require special scrutiny because their antimicrobial activity differs from “conventional” or “bulk”

silver

. However a careful examination of publicly available information for registered silver antimicrobials, including the label information in NPIRS data bases, patents, and manufacturers‟ descriptive/promotional materials , shows that all of the silver antimicrobials, including those comprised of metallic silver, derive their antimicrobial efficacy from the release of silver ions Ag(1+)

.

The STF NA is aware of the Agency‟s concerns about “nanosilver” and that some ultrafine particles may also exhibit si ze -related or morphological effects

. Such effects

occur in addition to , not instead of, the release of silver ions

. Further, a recent study 2



# demonstrates that silver nanoparticles lose their activity against E.coli when they are synthesized and maintained anaerobically, and are thus unable to generate silver cations by oxidation

. Under normal circumstances metallic silver surfaces are in

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

# equi lib rium with silver ions

. “C onventional” or “bulk” silver has no chemical or antimicrobial activity except via ions.

It seems fair to conclude, therefore, that registration of so many products as simply

“silver” is largely a regulatory artifact reflecting an earlier understanding of the antimicrobial activity of silver. Reconsideration focused on the role of the silver ion is appropriate “to ensure that each pesticide registration is based on current scientific knowledge regarding that pesticide, including its effects on human health

and the environment.” 3



# Among metal ions, the silver cation Ag+ has a high redox potential

. I t is a very “soft” Lewis acid that reacts strongly with Lewis bases, such as sulfur

. It is a potent antimicrobial even at very low concentrations, often at the level of micromoles per liter (μM /L ). This “oligodynamic” (inelegantly, “few -powerful ”) effect of silver was first noted by Nägeli, in 1893.

As part of its effort to prepare a thoughtful and comprehensive response to EPA‟s initial implementation of the Registration Review process, the Task Force has examined the full range of registered products covered by the Review

. Attachment 2 lists all currently registered products according to their chemical structure as related to ion release

. There are various mechanisms through which these materials release the silver ions responsible for their effectiveness, including oxidation, dissolution, and elution. Each of these is briefly described below:

(1) Oxidation: Metallic silver Ag(0) releases silver ions by oxidation ( Ag  Ag + 

# +

e - 

# )

. Metallic silver antimicrobials include silver-plated nylon filament for antimicrobial textiles; particulate silver for material-preservative applications; silver deposited by reduction in activated carbon or ceramic water filtration media; and colloidal silver, used widely in conjunction with chlorine in swimming pools but also in antimicrobial, disinfecting, and sterilizing sprays and solutions

. Ion c oncentrations are on the order of 2 μM for swimming pool maintenance up to 0.5 mM for disinfecting sprays.

The oxidation of silver must be balanced by a corresponding reduction of some other moiety which accepts the electron

– as, for instance, oxygen (O 2 

# + 2e - 

# 

2O - 

# ; and thus 4Ag + O 2 

#  2Ag 2 

# O). Therefore the rate of release of silver ions and the end product of oxidation depend not only on the metal itself and its configuration but also on what else is present on the metallic surface and in the

air or water in contact with it.

(2) Dissolution: Salts and other dissolving forms of silver release silver ions into water by dissolution (disassociation, deliquescence) and include materials with a very wide distribution of solubilities and configurations. The range of applications is also broad, including many material-preservative uses as well as antimicrobial sprays and solutions

. The rate and extent of dissolution depend not only on the solubility of the silver compound itself but also on what else is in the water

. T he

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

# presence of other dissolved substances reduces the rate and extent of

dissolution

.

Dissolving forms include silver glasses, materials preservatives used by incorporation into organic matrices

. These specialty glasses release silver ions by dissolving very slowly into moisture on the polymer surface

. In the most recently registered silver glass product (86101-2) the Agency has recognized silver ion Ag(1+), 072500, as the active ingredient rather than “silver,” 075201, as was the case for the older silver-glass products.

In further confirmation of the role of the ion, the active ingredient in the sixth (EPA Reg

. No .72977-6) in a series of silver dihydrogen citrate products is identified as silver ion Ag(1+), PC Code 072500; the preceding five products, all from the same manufacturer and incorporating the same ion-stabilization technology, identified “silver,” PC Code 072501, as the active ingredient.

(3) Elution: Ion-exchange carriers are used almost exclusively as material preservatives as means to incorporate silver ions into otherwise incompatible organic matrices (fibers, plastics)

. These materials carry silver ions Ag(1+) electrostatically adsorbed, not chemically bound, within their usually porous

molecular structure

. When exposed to moisture these substances elute silver ions in exchange for other positive ions in the water (H + 

# , Na + 

# , etc.) which replace

the electrosorbed silver within the carrier structure

. In contrast to the salts andother dissolving forms of silver, therefore, the rate and extent of elution from ionexchange carriers are enhanced by the presence of other cations in water, wit h more and faster elution into, for instance, physiological saline than into deionize d

water

. Elution is restricted and useful life extended by slow diffusion of ions

within the carrier.

In addition to materials preservative applications there is limited use of ionexchange carriers in water filters, humidifiers, dental water lines, and water softeners; in the latter case (EPA Reg

. No .59454-3), the active ingredient is again identified by the EPA as silver ion Ag(1+), PC Code 072500.

While these materials may differ in their mechanisms of action, the common and characteristic element, release of silver ion, should predominate for initial risk assessment purposes. To assist in EPA‟s Evaluation

, Attachment 3 lists use and usage information for each of the products in Attachment 2 to show the predominant areas of usage for each type

. Attachment 4 rearranges the same information to show that usage of silver antimicrobials falls into just five areas: (1) water treatment, mainly swimming pools and drinking water; (2) medical and dental applications; (3) liquid cleaners (for spray or mopping); (4) materials preservatives, the largest and broadest group; and (5) a very small group of agricultural uses for cleaning of equipment and premises.

In the following we examine “special cases” of silver compounds which the Agency has previously identified as being “not chemically similar

, ” or otherwise requiring separate

treatment f rom “silver and silver salts.” For these cases, too, the Task Force suggests

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

# that the initial and primary focus should be the silver ion as the moiety responsible for antimicrobial efficacy

. Only after completing that first-order assessment should the Agency consider the need for and value of extending its assessment for these types of products.

Zeolites

The letter accompanying the DCIs issued on February 29, 2012 4 

# stated that, “EPA believes that some of the products associated with the DCI(s) may contain “zeolite” active ingredients that are not correctly identified on the product labeling and/or Confidential Statements of Formula (CSF).” However, the registrants of all o f the zeolite-based products, all members of the STF NA

, met with the Agency in October 2010, to identify themselves and discuss the products, and have identified these materials correctly in their CSFs, as well as on virtually all of their labels, as shown not only in NPIRS, but also in Table 1 of the Preliminary Work Plan. 5 

# The Task Force is confident that no previously unknown zeolite products will have emerged in response to the February 29, DCI letter. If the Agency‟s intent is to include other ion -exchange carriers or other chemistries under the “zeolite” rubric, it needs to redefine its terminology.

That said, the zeolite registrants are pleased to have had the opportunity to meet with the Agency to discuss and document the structure and toxicity of m an -made zeolite A. 6


# The Silver Task Force appreciates the Agency‟s consequent agreement to bridging of data among products based on man-made zeolite A, 7 

# and understands that this agreement was later extended to include two new products based on zeolite X. The following comments are to supplement the 2010 discussion, to introduce recent literature, and to re-emphasize that the antimicrobial activity of zeolite-based silver antimicrobials, as well as any health or environmental concerns, are to be attributed to silver ions and not to their adsorption on the inert carrier or to the carrier itself.

The term zeolite is a well-defined chemical/mineralogical term referring specifically to tecto-alumino-silicates. However it appears that the Agency may have been using the term to refer more broadly to ion-exchange compounds in general. The Final Work Plan for the silver Registration Review stated that, “At this time, the Agency has concluded that zeolite-based silver compounds are not chemically similar to silver or silver

salts ”

. 8 

# This conclusion, initially reached by the Agency in 2004 9 

# , appears to be based primarily on a 90-day toxicity study in beagles for Antimicrobial Alphasan® RC 2000 (EPA Reg

. No.11631- 3) . This product is a silver sodium hydrogen zirconium phosphate (Ag-SHZP) made by exchanging silver ions for some of the sodium in a precursor zirconium phosphate and is not a zeolite. 10 

# Among the findings of the study were decreased body weight gain, elevated alkaline phosphatase, and thymic atrophy

. An NOAEL of 400 mg/kg/day was set

. Since this particular product contains 10% silver by weight, this is equivalent to 40 mg/kg/day of silver ion, which for humans would be 8000 times the oral RfD for silver, which is 0.005 mg/kg/day. 11

, 12



# Although zirconium phosphate is an ion-exchange carrier, it is not zeolite. The structure of the AlphaSan zirconium phosphate antimicrobials is unclear 13



# , but zirconium

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

# phosphates are generally lamellar (not cage-like) structures of oxides of zirconium and phosphorus and are thus phyllo- rather than tecto-alumino-silicates. The precursors of both silver-zeolites A and X are EPA-recognized non-food inerts. 14 

# Zirconium phosphate is not, though zirconium oxide is listed in NPIRS as an active ingredient for pesticides (PC Code 79090

– no current registrants)

. Not only is there no solid basis for extrapolating findings from zirconium phosphate to zeolite, but the findings for the high dosage of Ag-SHZP cited in the EPA 2004 memorandum are strikingly similar to those reported more recently for a much smaller dosage (9 mg/kg/day) of silver acetate

– an ionic solution

–

in rats. 15 

# The beagle findings are more persuasively attributed to the silver ion itself than to the ion-exchange carrier.

Finally, although silver zeolite, silver-zinc zeolite, and silver-copper zeolite (as well as Ag -SHZP) each have PC Codes and CAS numbers, none of these terms or numbers sufficiently defines the respective material

. All are made by replacing some portion of the sodium in their precursors with silver ions

. In “silver zeolite,” for instance, silver content can vary from effectively none to 22% by weight

. At present the actual silver

content is shown on the labels

. The suggestion that such products should instead be registered as 100% silver zeolite, for example, would be to eliminate information required by users to evaluate both the relative effectiveness and the comparative economics of these products, not to mention the degree of any risk found to be

associated with silver

. As the active moiety is in fact the silver ion, this is the essential component to be mentioned in the label description 16



# .

Small Particle Silver

The Silver Task Force North America appreciates that EPA has ongoing concerns about the data required to assess the risks of small silver particles

. The view that a unique dataset is required to assess the risks of small particle, or nanoscale, silver is derived largely from the recommendations of the 2009 FIFRA SAP on nanosilver which questioned whether there was sufficient data to support bridging arguments across silver compounds

.

An enormous amount of new information has been generated in the intervening three

years

. Google Scholar currently shows 13,800 new journal articles publish ed from

2009 to the present day containing the key word “silver nanoparticles

. ” Dozens of these papers contain new findings that directly address „data gaps‟ that were perceived to exist in areas such as aquatic toxicity 17

, 18

, 19

, 20

, 21

, 22

, 23

, 24

, 25

, 26 

# , mammalian toxicity 15

, 27

, 28

, 29

, 30

, 31 

# , and environmental fate 32

, 33

, 34

, 35



# . Furthermore, new information about the existence of nanoscale and colloidal silver among long-registered silver products 36 

# , as well as the release to silver nanoparticles from macro silver objects 37



# , calls into question some of the core assumptions that underpinned the SAP review, including that idea that nanoscale silver i s new and that human exposure to „bulk‟ metallic silver throughout history only resulted in exposure to silver ions rather than to nanoscale particles.

As new data has been generated, the fundamental question of the silver ion‟s role in silver particle toxicity, the so-called 0-hypothesis 38 

# , has been examined in a number of

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

# systems 2

, 15

, 20

, 26

, 31

, 39 

# . The most recent results are unequivocal that the silver ion is the active moiety responsible for the antimicrobial action of silver particles. Many other new research findings, using soluble silver salts as a control, show that nanoscale particulate silver presents an equal or lesser hazard than ionic silver 17

, 19

, 20

, 21

, 22

, 23

, 25

, 39

, 40



# . Other articles contradict the assumption that smaller particles of silver present a greater hazard than larger particles 24 

# or that small silver particles are more likely to bioaccummulate than ionic or larger particles 28

, 30



# .

Even more compelling are the results of a recent Danish study 15 

# comparing silver nanoparticles and silver acetate at 9 mg silver/kg/day, far above EPA argyria-protective

levels

. To quote from the abstract, “For the Ag -NP groups, no toxicological effects were

recorded

. For Ag-acetate, lower body weight gain..., increased plasma alkaline phosphatase..., decreased plasma urea...and lower absolute...and relative...thymus weight were recorded. In conclusion, these findings indicate toxicity of 9 mg/kg bw/day ionic silver but not of an equimolar Ag- NP dose.” While the nanoparticle results are interesting enough, those for silver acetate are particularly striking for the similarity to the findings for the silver zirconium phosphate product in dogs as summarized previously

. This provides strong support for our view that the chemical, antimicrobial, and toxicological effects of silver antimicrobials, including small particle size silver, are

to be attributed to silver ions.

Furthermore, two new oral toxicity studies in rats, comparing silver ions and silver nanoparticles, ha ve found that silver ion is the bioavailable species, leading to very similar organ distribution. 31

, 41 

# Both studies found that silver ion is much more likely to bioaccumulate compared to silver nanoparticles

. These new data, taken as a whole, provide ample evidence that there is no substantial difference in the toxicity profile of small silver particles and other silver compounds as they all share a common active moiety

– the silver ion.

Conclusion

The STFNA and its members are committed to working with the Agency to facilitate efficient and effective collection of necessary new data to support the Registration Review process. To begin that process, the STFNA has carefully reviewed the wide variety of silver compounds covered by the Registration Review and have taken into account the “special cases” EPA has previously identified

. We believe that the most scientifically supportable and process-efficient path forward is to consolidate review of all silver pesticide products

. Accordingly, the Agency should issue a single DCI for all silver compounds using silver ion as the common test substance regardless of particle size, additional active, and presence of zeolite

. Although there are several forms of silver-containing active ingredients under review, realization that the silver ion is the biologically active moiety for all silver antimicrobial products should facilitate bridging where scientifically justified, increasing efficiency for both the Agency and industry.

Alternatively, the Agency must, at a minimum, take administrative steps to put all products on a common schedule. A staged schedule prevents the industry from collaboration for data generation. This will lead to repetitive data submissions that will

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

# not add information value to the Agency‟s knowledgebase about silver hazards an d

risks

. However, this would not preclude the EPA from adding product-specific data requirements for classes of products with unique use patterns or exposure profiles. Nor would the issuance of a single DCI prevent modifications to labeling or dose limits for specific products or use patterns if such changes are scientifically justified. We appreciate EPA ‟s consideration and welcome our continued collaborative efforts to

maximize the results and conserve our resources.

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 

# References

1 

# Originally formed as the “U.S. Silver Task Force,” an unincorporated association, and recently

re -constituted, with substantially the same membership, as the “Silver Task Force North

America.”

2 

# Xiu, Z., Zhang, Q., Puppala, H.L., Colvin, V.L. & Alvarez, P.J. Negligible Particle-Specific Antibacterial Activity of Silver Nanoparticles. Nano Letters 12 , 4271-5 (2012).

3 

# 40 CFR Subpart C 155.40 (1)

4 

# United States. U.S. Environmental Protection Agency. Office of Chemical Safety and Pollution

Prevention. Upcoming Registration Review Data

- Call

- In for Silver . By Mark Hartman. N.p.: n.p., Feb. 29, 2012. Print.

5 

# United States. U.S. Environmental Protection Agency. Office of Prevention, Pesticides, and

Toxic Substances. Silver and Compounds Summary Document (Case 4082 and Case 5015): Registration Review Preliminary Work Plan . N.p.: n.p., 2002. Regulations.gov . Web. 01 Oct. 2012. <http://www.regulations.gov/#!documentDetail;D=EPA

- HQ

- OPP

- 2009

- 0334

- 0005>.

6 

# Hayes, J.H., Jr., Burin, G.J., & Janus, E.R.: A Review of the Chemistry, Toxicology, and Exposure Potential of the Zeolite-Based Antimicrobials, 08/27/10. Not in the docket, but a summary of the Oct 10 meeting and the slide presentation are available on regulations.gov Meeting Summary, EPA/U.S. Silver Task Force/Zeolite Registrants Meeting . N.p.: n.p.,

n.d. Regulations.gov

. Web. 10 Oct. 2012. <http://www.regulations.gov/#!documentDetail;D=EPA- HQ -OPP- 2009 -0334-0024>.

7 

# Hartman, Mark. "EPA Response to Registrant Request to Bridge Available Data to Silver/Zinc Zeolites." Letter to Gary Burin, Ph.D. 07 Dec. 2010. N.p.: n.p., n.d. N. pag. Regulations.gov

. Web. 01 Oct. 2012. <http://www.regulations.gov/#!documentDetail;D=EPA

- HQ

- OPP

- 2009

- 0334

- 0025>.

8 

# United States. U.S. Environmental Protection Agency. Office of Prevention, Pesticides, and

Toxic Substances. Silver and Compounds Final Work Plan . p3., n.d. Regulations.gov . Web. 10 Oct. 2012. <http://www.regulations.gov/#!documentDetail;D=EPA

- HQ

- OPP

- 2009

- 0334

- 0023>. The statement originated in the 2004 Memorandum and is repeated frequently in the same or

similar form in the docket.

9 

# Silver

– Report of the Antimicrobials Division Toxicity Endpoint Committee (ADTC); Memorandum from T.F. McMahon to Tony Kish/Marshall Swindell, 10/20/04. Although entitled “Silver...” this memorandum is in the docket for Zinc; Meeting Summary, EPA/U.S. Silver Task Force/Zeolite Registrants Meeting . N.p.: n.p., n.d. Regulations.gov . Web. 10 Oct. 2012. <http://www.regulations.gov/#!documentDetail;D=EPA- HQ -OPP- 2009 -0334- 0024> . A follow- up memo from 2009 is also in the Zinc docket, at EPA- HQ -OPP- 2009

- 0011 -0011.

10 

# See various US Patents assigned to the manufacturer, Toagosei (Japan), including 8,066,810; 8,231,883; 8,110205; 8,066,810.

11 

# United States. U.S. Environmental Protection Agency. Office of Prevention, Pesticides, and

Toxic Substances. Ionic Silver: Toxici ty and Weight of the Evidence . P 11

- 12.: n.p.,

n.d. Regulations.gov

. Web. 10 Oct. 2012. <http://www.regulations.gov/#!documentDetail;D=EPA

- HQ

- OPP

- 2009

- 0334

- 0004>.

12 

# IRIS (CASRN 7440- 22 -4).

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 13 

# The silver Preliminary Work Plan (EPA- HQ -OPP- 2009

- 0034 -0006, p. 27) shows only a unit cell of two zirconium oxides and three phosphates; the purportedly more detailed depiction on p. 4 of the Full Public Report submitted in Australia (http://www.nicnas.gov.au/publications/car/new/std/stdfullr/sd1081fr.pdf accessed 07/28/12) is incoherent, confused, and cannot be correct.

14 

# EPA Inertfinder; CAS Nos.68989- 22 -1 and 68989- 23

- 1.

15 

# Hadrup, N., Loeschner, K. & Bergström, A. Subacute oral toxicity investigation of nanoparticulate and ionic silver in rats. Archives of Toxicolo gy 86 , 543-551 (2011).

16 

# The same consideration applies for Ag-SHZP. There are registered products with 3.8% (EPA Reg. No. 11631-1), 10.0% (EPA Reg. No. 11631-2), and 3.1% (EPA Reg. No. 11631-13) by weight silver (that is, ionic silver). Ionic silver is th e real “active” ingredient, and this is what

should continue to be shown on the label.

17 

# Bilberg, K., Hovgaard, M.B., Besenbacher, F. &Baatrup, E. In Vivo Toxicity of Silver Nanoparticles and Silver Ions in Zebrafish (Daniorerio). Journal of Toxicology 293 784 (2012).

18 

# Bradford, A., Handy, R.D., Readman, J.W., Atfield, A.&Mühling, M. Impact of silver nanoparticle contamination on the genetic diversity of natural bacterial assemblages in

estuarine sediments. Environmental science & technology 43 , 4530-6 (2009 ).

19 

# Hoheisel, S.M. Effects of nanosilver on Daphnia magna and Pimephalespromelas. (2010).

20 

# Zhao, C.-M.& Wang, W.-X. Comparison of acute and chronic toxicity of silver nanoparticles and silver nitrate to Daphnia magna. Environmental toxicology and chemistry / SETAC 30 , 885- 92 (2011).

21 

# Allen, H.J. et al. Effects from filtration, capping agents, and presence/absence of food on the toxicity of silver nanoparticles to Daphnia magna. Environmental toxicology and chemistry /

SETAC 29 , 2742-50 (2010).

22 

# As ghari, S. et al. Toxicity of various silver nanoparticles compared to silver ions in Daphnia

magna. Journal of nanobiotechnology 10 , 14 (2012).

23 

# Laban, G., Nies, L.F., Turco, R.F., Bickham, J.W. &Sepúlveda, M.S. The effects of silver nanoparticles on fathead minnow (Pimephalespromelas) embryos. Ecotoxicology 19 , 185- 95 (2010).

24 

# Gorth, D.J., Rand, D.M. & Webster, T.J. Silver nanoparticle toxicity in Drosophila: size does

matter. International journal of nanomedicine 6, 343-50 (2011).

25 

# Chae, Y.J. et al. Evaluation of the toxic impact of silver nanoparticles on Japanese medaka (Oryziaslatipes). Aquatic Toxicology 94 , 320-7 (2009).

26 

# Miao, A.- J. et al. The algal toxicity of silver engineered nanoparticles and detoxification by exopolymeric substances. Environmental Pollution 157 , 3034-41 (2009).

27 

# Fondevila, M., Herrer, R., Casallas, M.C., Abecia, L.&Ducha, J.J. Silver nanoparticles as a potential antimicrobial additive for weaned pigs. Animal Feed Science and Technology 150 , 259- 269 (2009).

28 

# Lankveld, D.P.K. et al. The kinetics of the tissue distribution of silver nanoparticles of different

sizes. Biomaterials 31 , 8350-61 (2010).

29 

# Lansdown, A.B.G. A pharmacological and toxicological profile of silver as an antimicrobial agent in medical devices. Advances in pharmacological sciences 2010 , 910686 (2010).

# Silver Task Force North America
Position Paper on Registration Review of Silver Compounds

December 12, 2012 30 

# Boudreau, M.D. An Evaluation Of The Toxicological Effects Of Discrete Sizes Of Silver Nanoscale Particles (AGNP) In The Sprague Dawley Rat National Center For Toxicological.

31 

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# Attachments 1 through 4

Table of Contents

Attachment 1: Members of the Silv er Task Force Nort h Americ a ........................ 2
Attachment 2: Registered Silv er Antimicrobials, by Type ..................................... 3
Attachment 3: Usage of S ilver Antimicr obials ...................................................... 4
Attachment 4: Usage Categories for Silver Anti microbial s .................................... 5

List of Abbreviations .............................................................................................. 6

NOTE: These tables and lists are to be regarded as proposals, compiled primarily by one person, who is responsible for the content and arrangement. Although the comments of all member s have been requested and incorporated, the content does not necessarily represent the views of all of the members or of the STF NA as a group.

# Attachment 1

Members of the Silver Task Force Nort h America as of October 17, 2012

1. Apyron Technologies 2. BASF Corporation

3. Bio-Gate AG
4. BioLab, Inc. 5. Calgon Carbon Corporation

6. Chemviron Carbon Limited 7. Clariant Corporation 8. Corning Incorporated 9. The Dow Chemical Company 10. Eastman Kodak Company
11. Enrich Products, Inc. 12. Fairey Industrial Ceramics, Ltd. 13. Fuji Chemical Industries, Ltd. 14. Ishizuka Glass Co., Ltd. 15. King Technology, Inc. 16. KX Technologies LLC 17. LiquiTech, Inc. 18. Mason Chemical Company 19. Microban Products Company

20. NanoBioMatters Industries S.L.

21. NanoHorizons Inc. 22. Noble Biomaterials, Inc. 23. Pool Products Packaging Corporation 24. ProEdge Dental Products, Inc.

25. RUDOLF GmbH 26. Sanosil International, LLC 27. sBioMed, LLC

28. Sciessent LLC 29. Sinanen Zeomic Co., Ltd.

30. Taiki USA Inc. 31. Sterisil, Inc.

32. Thomson Research Asso ciates International Ltd 33. Thor Specialties, Inc. 34. Zodiac Pool Systems, Inc.

# Metallic silve r Colloidal silve r Silver-glas s
Reg # Chemistry Year Ag PCC % Reg # Chemistry Year Ag PCC % Reg # Chemistry Year Ag PCC %

70927-1 Ag on nyl 1998 72501 17 7124-101 Col Ag 1993 72501 0.8 11631-5 Ag-glass 2008 72501 1.8

70927-2 Ag on nyl 2008 72501 15 10324-18 Col Ag 1971 72501 0.8 40810-23 Ag-glass 2003 72501 0.41

70927-3 Ag on nyl 2008 72501 9 57787-21 Col Ag 1997 72501 0.8 40810-24 Ag-glass 2003 72501 0.37

70927-4 Ag on nyl 2008 72501 13 68161-1 Col Ag 1954 72501 0.8 40810-26 Ag-glass 2003 72501 1.57

70927-5 Ag on nyl 2009 72501 20 73499-1 Col Ag 2002 72501 0.001 40810-27 Ag-glass 2003 72501 1.18

70927-6 Ag on nyl 2011 72501 5 73499-2 Col Ag 2003 72501 0.0032 73148-1 Ag-glass 2000 72501 1.6

84214-1 Ag on nyl 2007 72501 17 75829-1 Col Ag 2004 72501 0.0015 73148-2 Ag-glass 2001 72501 0.42

84214-2 Ag on nyl 2009 72501 9 84526-1 Col Ag/AgNO3 2008 72501 0.01 73148-3 Ag-glass 2001 72501 1.8

84214-3 Ag on nyl 2009 72501 13 84526-2 Col Ag/AgNO3 2009 72501 0.1 73148-4 Ag-glass 2006 72501 2.5

85375-1 Ag on nyl 2010 72501 0.77 84526-3 Col Ag/AgNO3 2010 72501 0.05 73148-5 Ag-glass 2005 72501 2.6

84526-4 Col Ag/AgNO3 2011 72501 0.034 73148-6 Ag-glass 2006 72501 1.8 

# Metallic silver particle s 84526-5 Col Ag/AgNO3 2012 72501 0.01 73148-7 Ag-glass 2008 72501 0.9

Reg # Chemistry Year Ag PCC % 84545-4 Col Ag 2009 72501 0.03 82415-8 Ag-glass 1998 72501 1.8

69096-3 AgForFilt 1997 72501 99.51 84545-8 Col Ag 2008 72501 0.03 86106-1 Ag-glass 2009 72500 1.4

82691-2 Ag partcl 2006 72501 100 84545-11 Col Ag 2011 72501 0.015

83587-3 Ag partcl 2007 72501 99.9 

# Silver zeolites

84146-1 Ag partcl 2008 72501 100 

# Silver salts, in order of increasing solubilit y Reg # Chemistry Year Ag PCC %

85249-1 Ag partcl 2011 72599 19.3 Reg # Chemistry Year Ag PCC % 82415-3 AgZeolite 1994 221700 3.5

85249-2 Ag partcl 2011 72599 19.3 71661-1 AgI 2002 72501 0.0095 88165-1 AgZeolite 2007 72501 22

3432-64 AgO 1996 129097 2 88165-2 AgZeolite 2008 72501 10 

# Silver-impregnated activated carbo n 3432-71 AgO 1998 129097 1 88165-3 AgZeolite 2009 72501 0.15

Reg # Chemistry Year Ag PCC % 53735-11 AgCl 2005 72506 0.5 71227-1 AgZeolite 1999 72501 2.5

35900-2 Ag on A/C 1975 72501 1.05 87396-1 AgCl 2011 72506 4 71227-4 AgZeolite 2001 72501 4.93

35900-3 Ag on A/C 1984 72501 0.07 88088-1 AgCl 2005 72506 4 71227-5 AgZeolite 2001 72501 0.59

37589-2 Ag on A/C 1985 72501 0.2 88088-2 AgCl 2006 72506 99.6 71227-6 AgZeolite 2001 72501 0.3

37589-4 Ag on A/C 1985 72501 1.05 88088-3 AgCl 2008 72506 4 82415-2 AgZn zeol 1994 72501 6.5

37589-5 Ag on A/C 1985 72501 0.75 39444-9 AgCl (?) 1995 72501 1 40810-18 AgZn zeol 2002 72501 0.44

37589-8 Ag on A/C 1996 72501 0.1 3090-225 AgCl/TiO2 2009 72506 2 40810-19 AgZn zeol 2002 72501 2.2

54625-2 Ag on A/C 1986 72501 0.016 49403-34 AgCl/TiO2 2007 72506 20 82415-1 AgCu zeol 1993 72501 3.5

58295-1 Ag on A/C 1988 72501 0.026 49403-36 AgCl/TiO2 2008 72506 2 71227-7 AgCu zeol 2004 72501 3.5

58295-2 Ag on A/C 1989 72501 1.05 49403-38 AgCl/TiO2 2009 72506 2 87731-2 Ag zeol X 2011 72501 2.2

58295-3 Ag on A/C 1990 72501 0.5 84189-## AgCl/TiO2 ---- 72506 87731-1 Ag zeol X 2011 72503 0.5

62275-1 Ag on A/C 1990 72501 0.07 83315-1 AgCitrate 2009 72501 0.78

68934-1 Ag on A/C 1998 72501 0.001166 59441-8 AgSO4 2007 72511 98.5 

# Silver cla y
70852-6 Ag on A/C 2009 72501 0.06 5185-498 AgNO3 2004 72503 63.5 Reg # Chemistry Year Ag PCC %

74802-2 Ag on A/C 2004 72501 1.05 69625-2 AgNO3 2004 72503 1.72 87722-1 Ag-clay 2011 72501 0.5

75456-1 Ag on A/C 2003 72501 0.05 72992-1 AgNO3 2001 72503 2.83 87722-2 Ag-clay 2011 72501 0.5

75456-3 Ag on A/C 2012 72501 1.05 79662-1 AgNO3 2008 72503 0.14 87722-3 Ag-clay 2011 72501 0.5

85531-1 Ag on A/C 2009 72501 0.27 84630-2 AgNO3 2010 72503 0.53 87722-4 Ag-clay 2011 72501 3

87256-1 Ag on A/C 2011 72501 0.5 85531-2 AgNO3 2012 72503 20 

# Silver sodium hydrogen zirconium phosph a Silver-impregnated ceramic s Silver dihydrogen citrat e Reg # Chemistry Year Ag PCC %

Reg # Chemistry Year Ag PCC % Reg # Chemistry Year Ag PCC % 11631-2 AgNaHZrPO 2000 72560 99.9

67712-1 Ag on cer 2002 72501 3.51 67619-18 SDC 2006 72501 0.003 11631-3 AgNaHZrPO 2001 72560 99.9

67712-5 Ag on cer 2002 72501 2.33 70404-9 SDC 2005 72501 0.24 11631-4 AgNaHZrPO 2001 72560 31

67712-15 Ag on cer 2006 72501 0.92 72977-1 SDC 2001 72501 0.24 74079-1 AgNaHZrPO 2001 72560 99.9

71332-5 Ag on cer 2007 72501 0.25 72977-2 SDC 2001 72501 0.0012 74079-2 AgNaHZrPO 2008 72560 31

73667-5 Ag on cer 2002 72501 1.4 72977-3 SDC 2003 72501 0.003 74079-3 AgNaHZrPO 2009 72560 99.9

73667-6 Ag on cer 2002 72501 0.7 72977-4 SDC 2009 72501 0.005

73667-7 Ag on cer 2002 72501 0.63 72977-5 SDC 2008 72501 0.003 

# Silver in ion-exchange resin s
79630-1 Ag on cer 2004 72501 1.4 72977-6 SDC 2009 72500 0.24 Reg # Chemistry Year Ag PCC %

79630-2 Ag on cer 2005 72501 1.4 75277-1 SDC 2009 72501 0.003 59454-3 Ag+/i-x 2009 72500 0.9

84020-1 SDC (?) 2007 72501 0.447 83315-2 Ag+/i-x 2009 72501 17.5 

# Silver apatit e
Reg # Chemistry Year Ag PCC % 

# Ion-polymer complexe s
68317-1 AgApatite 1995 72501 1.5 Reg # Chemistry Year Ag PCC %

68317-2 AgApatite 1995 72501 2.03 707-313 Ion/pol cplx 2007 72501 2.95

68317-4 AgApatite 1997 72501 1.5 464-783 Ion/pol cplx 2012 72501 2.2 

# Attachment 2: Registered Silver Antimicrobials, by Type

# +: New since Preliminary Work Plan ! : Corrected 

# M e t a lli c s il ver Sil ver sa lt s, i n or d er o f i ncreas i ng so l u bilit y Sil ver zeo lit es

Are a Secto r Form Metho d Reg # Chemistr y Are a Secto r Form Metho d Reg # Chemistr y A re a Secto r Form Metho d Reg # Chemistr y Mpres Fiber PltFibr ! Incorp 70927-1 Ag on nyl AgrP&E Farm RTUSol Spray 71661-1 AgI Mpres Adh/Se Pw/Dst ! Incorp 82415-3 AgZeolite
Mpres Fiber PltFibr ! Incorp 70927-2 Ag on nyl AgrP&E Egg RTUSol Spray 71661-1 AgI Mpres Fiber Pw/Dst ! Incorp 82415-3 AgZeolite
Mpres Fiber PltFibr ! Incorp 70927-3 Ag on nyl AgrP&E Mshrm RTUSol Spray 71661-1 AgI Mpres Apparel Pw/Dst ! Incorp 82415-3 AgZeolite
Mpres Fiber PltFibr ! Incorp 70927-4 Ag on nyl ResPA HdSfc RTUSol Spr/Mop 71661-1 AgI Mpres PlFiMoP Pw/Dst ! Incorp 82415-3 AgZeolite
Mpres Fiber PltFibr ! Incorp 70927-5 Ag on nyl ResPA Transp RTUSol Spr/Mop 71661-1 AgI Mpres PapCo Pw/Dst ! Incorp 82415-3 AgZeolite
Mpres+ Fiber+ PltFibr+ Incorp+ 70927-6 Ag on nyl MdP&E Vet RTUSol Spr/Mop 71661-1 AgI Mpres Paint Pw/Dst ! Incorp 82415-3 AgZeolite
Mpres Fiber PltFibr!! Incorp 84214-1 Ag on nyl Spool SPool SolConc OPour 3432-64 AgO Mpres Adhe Pw/Dst ! Incorp 82415-3 AgZeolite
Mpres+ Fiber+ PltFib+! Incorp+ 84214-2 Ag on nyl Spool Spa SolConc OPour 3432-71 AgO Mpres PlVPvc Pw/Dst ! Incorp 71227-1 AgZeolite
Mpres+ Fiber+ PltFib+! Incorp+ 84214-3 Ag on nyl Mpres+ FibText RTUSol+ Incorp+ 3090-225 AgCl/TiO2 Mpres Adh/Se Pw/Dst ! Incorp 71227-1 AgZeolite
Mpres+ Textls+ PltFib+! Blend+ 85375-1 Ag on nyl Mpres+ Adh/Se+ RTUSol+ Incorp+ 3090-225 AgCl/TiO2 Mpres Fiber Pw/Dst ! Incorp 71227-1 AgZeolite
Mpres+ Misc+ RTUSol+ Incorp+ 3090-225 AgCl/TiO2 Mpres Coa/Fi Pw/Dst ! Incorp 71227-1 AgZeolite 

# Metallic silver particles Mpres+ PlFiMoP RTUSol+ Incorp+ 3090-225 AgCl/TiO2 Mpres UpgCo Pw/Dst ! Incorp 71227-1 AgZeolite



# Area Sector Form Method Reg # Chemistry HumDW IndWPU SolConc OPour 39444-9 AgCl (?) Mpres HVAC Pw/Dst ! Incorp 71227-1 AgZeolite
HumDW+ WPurU+ Pw/Dst+ MUP+ 69096-3 AgForFilt Mpres FibText RTUSol Incorp 49403-34 AgCl/TiO2 Mpres PlVPvc Pw/Dst ! Incorp 71227-4 AgZeolite
Mpres PlVPvc Pw/Dst ! Incorp 82691-2 Ag partcl Mpres Adh/Se RTUSol Incorp 49403-36 AgCl/TiO2 Mpres Adh/Se Pw/Dst Incorp 71227-4 AgZeolite

Mpres Adh/Se Pw/Dst ! Incorp 82691-2 Ag partcl Mpres Misc RTUSol Incorp 49403-36 AgCl/TiO2 Mpres Coa/Fi Pw/Dst Incorp 71227-4 AgZeolite
Mpres Fiber Pw/Dst ! Incorp 82691-2 Ag partcl Mpres PlFiMoP RTUSol Incorp 49403-36 AgCl/TiO2 Mpres PlVPvc Pw/Dst ! Incorp 71227-5 AgZeolite
Mpres+ Cer/Gla Pw/Dst+ Incorp+ 83587-3 Ag partcl Mpres FibText RTUSol Incorp 49403-36 AgCl/TiO2 Mpres Adh/Se Pw/Dst ! Incorp 71227-5 AgZeolite
Mpres+ Pla/Cmp Pw/Dst+ Incorp+ 83587-3 Ag partcl Mpres+ FibText RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres Fiber Pw/Dst ! Incorp 71227-5 AgZeolite
Mpres+ Coatng+ Pw/Dst+ Incorp+ 83587-3 Ag partcl Mpres+ Adh/Se+ RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres Coa/Fi Pw/Dst ! Incorp 71227-5 AgZeolite
Mpres+ Fiber+ Pw/Dst+ Incorp+ 83587-3 Ag partcl Mpres+ Misc+ RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres PlVPvc Pw/Dst ! Incorp 71227-6 AgZeolite
Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 83587-3 Ag partcl Mpres+ PiFiMoP RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres Adh/Se Pw/Dst ! Incorp 71227-6 AgZeolite
Mpres+ Cer/Gla Pw/Dst+ Incorp+ 84146-1 Ag partcl Mpres+ Coa/Fi+ RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres Fiber Pw/Dst ! Incorp 71227-6 AgZeolite
Mpres+ Pla/Cmp Pw/Dst+ Incorp+ 84146-1 Ag partcl SPoSpa SPool ImprMat ESCart 53735-11 AgCl Mpres Coa/Fi Pw/Dst ! Incorp 71227-6 AgZeolite
Mpres+ Fiber+ Pw/Dst+ Incorp+ 84146-1 Ag partcl SPoSpa Spa ImprMat ESCart 53735-11 AgCl MedDES Coa/Fi+ Pw/Dst+ Incorp+ 88165-1 AgZeolite
Mpres+ Coatng+ Pw/Dst+ Incorp+ 84146-1 Ag partcl Mpres+ FibText RTUSol+ Incorp+ 84189-## AgCl/TiO2 MedDES Adh/Se+ Pw/Dst+ Incorp+ 88165-1 AgZeolite
Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 84146-1 Ag partcl Mpres+ FibText RTUSol+ Incorp+ 87396-1 AgCl Mpres+ Paint+ Pw/Dst+ Incorp+ 88165-1 AgZeolite
Mpres+ FibText Pw/Dst+ Incorp+ 85249-1 Ag partcl Mpres FibText SolConc Incorp 88088-1 AgCl MedDES Fiber+ Pw/Dst+ Incorp+ 88165-2 AgZeolite
Mpres+ FibText Pw/Dst+ MUP+ 85249-2 Ag partcl Mpres+ Textls+ Pw/Dst+ MUP+ 88088-2 AgCl MedDES Coa/Fi+ Pw/Dst+ Incorp+ 88165-2 AgZeolite
Mpres FibText RTUSol Incorp 88088-3 AgCl MedDES Adh/Se+ Pw/Dst+ Incorp+ 88165-2 AgZeolite 

# Silver-impregnated activated carbon MdP&E+ DenWL+ Tablet Dissol+ 83315-1 AgCitrate Mpres+ Paint+ Pw/Dst+ Incorp+ 88165-2 AgZeolite



# Area Sector Form Method Reg # Chemistry Mpres PlVPvc Pw/Dst Incorp 59441-8 AgSO4 HumDW+ WPurU+ ImprMat+ ESCart+ 88165-3 AgZeolite
HumDW WPurU ImprMat ESCart 35900-2 Ag on A/C Mpres Adh/Se Pw/Dst Incorp 59441-8 AgSO4 Mpres PlVPvc SolConc Incorp 40810-18 AgZn zeol
HumDW WPurU ImprMat ESCart 35900-3 Ag on A/C Mpres Fiber Pw/Dst Incorp 59441-8 AgSO4 Mpres Adh/Se Pw/Dst Incorp 40810-18 AgZn zeol
HumDW WPurU ImprMat ESCart 37589-2 Ag on A/C Mpres Fiber Powder Incorp 59441-8 AgSO4 Mpres Fiber Pw/Dst Incorp 40810-18 AgZn zeol
HumDW WPurU ImprMat MUInc 37589-4 Ag on A/C Mpres PlaCoFi Powder Incorp 59441-8 AgSO4 Mpres Coa/Fi Pw/Dst Incorp 40810-18 AgZn zeol

HumDW WPurU ImprMat ESCart 37589-5 Ag on A/C Mpres Adh/Se Powder Incorp 59441-8 AgSO4 Mpres HVAC Pw/Dst Incorp 40810-18 AgZn zeol
HumDW WPurU ImprMat ESCart 37589-8 Ag on A/C Spool SPool ImprMat ESCart 5185-498 AgNO3 Mpres DenWL Pw/Dst Incorp 40810-18 AgZn zeol
HumDW WPurU ImprMat ESCart 54625-2 Ag on A/C HumDW WPurU ImprMat MUInc 69625-2 AgNO3 Mpres+ PlFiMoP Pw/Dst+ MUP+ 40810-19 AgZn zeol
HumDW WPurU ImprMat ESCart 58295-1 Ag on A/C Agr+ CutFlwr SolConc+ Soak+ 72992-1 AgNO3 Mpres+ Fiber+ Pw/Dst+ MUP+ 40810-19 AgZn zeol
HumDW WPurU ImprMat ESCart 58295-2 Ag on A/C MdP&E DenWL Tablet Dissol 79662-1 AgNO3 Mpres+ Coa/Fi+ Pw/Dst+ MUP+ 40810-19 AgZn zeol
HumDW WPurU ImprMat ESCart 58295-3 Ag on A/C Mpres+ Textls+ SolConc+ Dp/Spry 84630-2 AgNO3 Mpres+ Adh/Se+ Pw/Dst+ MUP+ 40810-19 AgZn zeol
HumDW WPurU ImprMat MUInc 62275-1 Ag on A/C HumDW+ ImprFl+ SolConc+ MUInc+ 85531-2 AgNO3 Mpres+ Misc+ Pw/Dst+ MUP+ 40810-19 AgZn zeol
HumDW WPurU ImprMat ESCart 68934-1 Ag on A/C Mpres Adh/Se Pw/Dst ! Incorp 82415-2 AgZn zeol

HumDW+ WPurU+ ImprMat+ ESCart+ 70852-6 Ag on A/C 

# Silver dihydrogen citrate Mpres PapCo Pw/Dst Incorp 82415-2 AgZn zeol
HumDW WPurU ImprMat ESCart 74802-2 Ag on A/C 

# Area Sector Form Method Reg # Chemistry Mpres PntDyP Pw/Dst Incorp 82415-2 AgZn zeol
HumDW WPurU ImprMat MUInc 75456-1 Ag on A/C ResPA HdSfc RTUSol Spr/Mop 67619-18 SDC Mpres Adh/Se Pw/Dst ! Incorp 71227-7 AgCu zeol
HumDW+ WPurU+ ImprMat+ MUInc+ 75456-3 Ag on A/C ResPA Transp RTUSol Spr/Mop 67619-18 SDC Mpres Fiber Pw/Dst Incorp 71227-7 AgCu zeol
HumDW+ WPurU+ ImprMat+ ESCart+ 85531-1 Ag on A/C MdP&E HdSfc RTUSol Spr/Mop 67619-18 SDC Mpres PlVPvc Pw/Dst Incorp 82415-1 AgCu zeol
HumDW+ WPurU+ ImprMat+ MUP+ 87256-1 Ag on A/C MUP+ MUP+ SolConc+ MUP+ 70404-9 SDC Mpres Adh/Se Pw/Dst ! Incorp 82415-1 AgCu zeol
MUP+ MUP+ SolConc+ MUP+ 72977-1 SDC Mpres Fiber Pw/Dst Incorp 82415-1 AgCu zeol 

# Silver-impregnated ceramics ResPA HdSfc RTUSol Spr/Mop 72977-2 SDC Mpres PapCo Pw/Dst Incorp 82415-1 AgCu zeol



# Area Sector Form Method Reg # Chemistry ResPA Transp RTUSol Spr/Mop 72977-2 SDC Mpres+ PlFiMoP Pw/Dst+ Incorp+ 87731-1 Ag zeol X
Spool SPool ImprMat ESCart 67712-1 Ag on cer MdP&E HdSfc RTUSol Spr/Mop 72977-2 SDC Mpres+ Fiber+ Pw/Dst+ Incorp+ 87731-1 Ag zeol X
Spool Spa ImprMat OPour 67712-15 Ag on cer MdP&E Vet RTUSol Spr/Mop 72977-2 SDC Mpres+ Coa/Fi+ Pw/Dst+ Incorp+ 87731-1 Ag zeol X
Spool SPool ImprMat ESCart 67712-5 Ag on cer ResPA HdSfc RTUSol Spr/Mop 72977-3 SDC Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 87731-1 Ag zeol X
HumDW+ WPurU+ Pw/Dst+ MUP+ 73667-5 Ag on cer ResPA Transp RTUSol Spr/Mop 72977-3 SDC Mpres+ Misc+ Pw/Dst+ Incorp+ 87731-1 Ag zeol X
HumDW+ WPurU+ Pw/Dst+ MUP+ 73667-6 Ag on cer MdP&E HdSfc RTUSol Spr/Mop 72977-3 SDC Mpres+ PlFiMoP Pw/Dst+ Incorp+ 87731-2 Ag zeol X
HumDW+ WPurU+ Pw/Dst+ MUP+ 73667-7 Ag on cer MdP&E Vet RTUSol Spr/Mop 72977-3 SDC Mpres+ Fiber+ Pw/Dst+ Incorp+ 87731-2 Ag zeol X
ResPA Humdfr ImprMat Place 79630-1 Ag on cer ResPA+ HdSfc+ RTUSol+ Spr/Mop 72977-4 SDC Mpres+ Coa/Fi+ Pw/Dst+ Incorp+ 87731-2 Ag zeol X
HumDW WPurU ImprMat MUInc 79630-2 Ag on cer ResPA HdSfc RTUSol Spr/Mop 72977-5 SDC Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 87731-2 Ag zeol X
HumDW WPurU ImprMat MUInc 71332-5 Ag on cer ResPA Transp RTUSol Spr/Mop 72977-5 SDC Mpres+ Misc+ Pw/Dst+ Incorp+ 87731-2 Ag zeol X
MdP&E HdSfc RTUSol Spr/Mop 72977-5 SDC 

# Silver apatite MdP&E Vet RTUSol Spr/Mop 72977-5 SDC 

# Silver clay

Area Sector Form Method Reg # Chemistry ResPA+ Humdfr+ SolConc+ Dilute+ 72977-6 SDC 

# Area Sector Form Method Reg # Chemistry
Mpres PlVPvc Pw/Dst Incorp 68317-1 AgApatite ResPA+ HdSfc+ RTUSol+ Spray+ 75277-1 SDC Mpres+ PlFiMoP Pw/Dst+ Incorp+ 87722-1 Ag-clay
Mpres Adh/Se Pw/Dst Incorp 68317-1 AgApatite MdP&E DenWL Tablet Dissol 84020-1 SDC (?) Mpres+ Fiber+ Pw/Dst+ Incorp+ 87722-1 Ag-clay
Mpres PapCo Pw/Dst Incorp 68317-1 AgApatite Mpres+ Coa/Fi+ Pw/Dst+ Incorp+ 87722-1 Ag-clay

Mpres PntDyP Pw/Dst Incorp 68317-1 AgApatite 

# Ion-polymer complexes Mpres+ UpgCo+ Pw/Dst+ Incorp+ 87722-1 Ag-clay
Mpres PlVPvc Pw/Dst Incorp 68317-2 AgApatite 

# Area Sector Form Method Reg # Chemistry Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 87722-1 Ag-clay
Mpres Adh/Se Pw/Dst Incorp 68317-2 AgApatite Mpres Fiber SolConc Incorp 707-313 Ion/pol cplx Mpres+ PlFiMoP Pw/Dst+ Incorp+ 87722-2 Ag-clay
Mpres PapCo Pw/Dst Incorp 68317-2 AgApatite Mpres Coa/Fi SolConc Incorp 707-313 Ion/pol cplx Mpres+ PlFiMoP Pw/Dst+ Incorp+ 87722-3 Ag-clay
Mpres PntDyP Pw/Dst Incorp 68317-2 AgApatite Mpres Fiber SolConc Incorp 464-783 Ion/pol cplx Mpres+ Fiber+ Pw/Dst+ Incorp+ 87722-3 Ag-clay
HumDW WPurU ImprMat MUInc 68317-4 AgApatite Mpres Coa/Fi SolConc Incorp 464-783 Ion/pol cplx Mpres+ Coa/Fi+ Pw/Dst+ Incorp+ 87722-3 Ag-clay
Mpres+ UpgCo+ Pw/Dst+ Incorp+ 87722-3 Ag-clay


# "Colloidal silver" Silver-glass Mpres+ Paint+ Pw/Dst+ Incorp+ 87722-3 Ag-clay



# Area Sector Form Method Reg # Chemistry Area Sector Form Method Reg # Chemistry Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 87722-3 Ag-clay
Spool SPool SolConc OPour 10324-18 Col Ag Mpres PlFi Pw/Dst Incorp 11631-5 Ag-glass Mpres+ PlFiMoP Pw/Dst+ Incorp+ 87722-4 Ag-clay
Spool SPool SolConc OPour 57787-21 Col Ag Mpres Adh/Se Pw/Dst Incorp 11631-5 Ag-glass Mpres+ Fiber+ Pw/Dst+ Incorp+ 87722-4 Ag-clay
Spool SPool SolConc OPour 68161-1 Col Ag Mpres Fiber Pw/Dst Incorp 11631-5 Ag-glass Mpres+ Coa/Fi+ Pw/Dst+ Incorp+ 87722-4 Ag-clay
Spool SPool SolConc OPour 7124-101 Col Ag Mpres PapCo Pw/Dst Incorp 11631-5 Ag-glass Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 87722-4 Ag-clay

ResPA HdSfc RTUSol Spr/Mop 73499-1 Col Ag Mpres Paint Pw/Dst Incorp 11631-5 Ag-glass Mpres+ Paint+ Pw/Dst+ Incorp+ 87722-4 Ag-clay
ResPA Transp RTUSol Spr/Mop 73499-1 Col Ag Mpres+ Adh/Se+ Pw/Dst+ MUP+ 40810-23 Ag-glass Mpres+ Misc+ Pw/Dst+ Incorp+ 87722-4 Ag-clay
ResPA HdSfc RTUSol Spr/Mop 73499-2 Col Ag Mpres+ Coa/Fi+ Pw/Dst+ MUP+ 40810-23 Ag-glass

MdP&E HdSfc RTUSol Spr/Mop 73499-2 Col Ag Mpres+ PlFiMoP Pw/Dst+ MUP+ 40810-23 Ag-glass 

# Silver sodium hydrogen zirconium phosphate

MdP&E DenWL RTUSol Circ 73499-2 Col Ag Mpres+ Fiber+ Pw/Dst+ MUP+ 40810-23 Ag-glass 

# Area Sector Form Method Reg # Chemistry
MdP&E DenWL SolConc Circ 75829-1 Col Ag Mpres+ Misc+ Pw/Dst+ MUP+ 40810-23 Ag-glass Mpres PlVPvc Pw/Dst Incorp 11631-2 AgNaHZrPO
ResPA HdSfc RTUSol Spr/Mop 84526-1 Col Ag Mpres PlVPvc Pw/Dst ! Incorp 40810-24 Ag-glass Mpres Adh/Se Pw/Dst Incorp 11631-2 AgNaHZrPO
MdP&E HdSfc RTUSol Spr/Mop 84526-1 Col Ag Mpres Adh/Se Pw/Dst Incorp 40810-24 Ag-glass Mpres Fiber Pw/Dst Incorp 11631-2 AgNaHZrPO
MdP&E Vet RTUSol Spr/Mop 84526-1 Col Ag Mpres Fiber Pw/Dst Incorp 40810-24 Ag-glass Mpres Coa/Fi Pw/Dst Incorp 11631-2 AgNaHZrPO
ResPA+ HdSfc+ SolConc+ Spr/Mop 84526-2 Col Ag Mpres HVAC Pw/Dst Incorp 40810-24 Ag-glass Mpres CoSpPip Pw/Dst Incorp 11631-2 AgNaHZrPO
MdP&E+ HdSfc+ SolConc+ Spr/Mop 84526-2 Col Ag Mpres DenWL Pw/Dst Incorp 40810-24 Ag-glass Mpres UpgCo Pw/Dst Incorp 11631-2 AgNaHZrPO

MdP&E+ Vet+ SolConc+ Spr/Mop 84526-2 Col Ag Mpres+ Adh/Se+ Pw/Dst+ MUP+ 40810-26 Ag-glass Mpres HVAC Pw/Dst Incorp 11631-2 AgNaHZrPO

IndCW+ CoolW+ SolConc+ Circ+ 84526-3 Col Ag Mpres+ Coa/Fi+ Pw/Dst+ MUP+ 40810-26 Ag-glass Mpres DrkWtr Pw/Dst Incorp 11631-2 AgNaHZrPO
IndPap PuPap+ SolConc+ Circ+ 84526-3 Col Ag Mpres+ PlFiMoP Pw/Dst+ MUP+ 40810-26 Ag-glass Mpres Other Pw/Dst Incorp 11631-2 AgNaHZrPO
IndCW+ CoolW+ SolConc+ Circ+ 84526-4 Col Ag Mpres+ Fiber+ Pw/Dst+ MUP+ 40810-26 Ag-glass Mpres PlVPvc Pw/Dst Incorp 11631-3 AgNaHZrPO
IndPap PuPap+ SolConc+ Circ+ 84526-4 Col Ag Mpres+ Misc+ Pw/Dst+ MUP+ 40810-26 Ag-glass Mpres Adh/Se Pw/Dst Incorp 11631-3 AgNaHZrPO
IndCW+ CoolW+ SolConc+ Circ+ 84526-5 Col Ag Mpres PlVPvc Pw/Dst ! Incorp 40810-27 Ag-glass Mpres Fiber Pw/Dst Incorp 11631-3 AgNaHZrPO
IndPap PuPap+ SolConc+ Circ+ 84526-5 Col Ag Mpres Adh/Se Pw/Dst ! Incorp 40810-27 Ag-glass Mpres Coa/Fi Pw/Dst Incorp 11631-3 AgNaHZrPO
MdP&E+ HdSfc+ SolConc+ Spr/Mop 84545-11 Col Ag Mpres Fiber Pw/Dst ! Incorp 40810-27 Ag-glass Mpres UpgCo Pw/Dst Incorp 11631-3 AgNaHZrPO
PbbAcc HdSfc+ SolConc+ Spr/Mop 84545-11 Col Ag Mpres PlVPvc Pw/Dst Incorp 73148-1 Ag-glass Mpres HVAC Pw/Dst Incorp 11631-3 AgNaHZrPO
AgrP&E HdSfc+ SolConc+ Spr/Mop 84545-11 Col Ag Mpres Fiber Pw/Dst Incorp 73148-1 Ag-glass Mpres DrkWtr Pw/Dst Incorp 11631-3 AgNaHZrPO
ResPA+ HdSfc+ SolConc+ Spr/Mop 84545-4 Col Ag Mpres PapCo Pw/Dst Incorp 73148-1 Ag-glass Mpres Other Pw/Dst Incorp 11631-3 AgNaHZrPO
MdP&E+ HdSfc+ SolConc+ Spr/Mop 84545-4 Col Ag Mpres HVAC Pw/Dst Incorp 73148-1 Ag-glass Mpres PlVPvc Pw/Dst Incorp 11631-4 AgNaHZrPO
Mpres+ PlFiMoP RTUSol+ Incorp+ 3090-225 AgCl/TiO2 Mpres PntDyP Pw/Dst Incorp 73148-1 Ag-glass Mpres Adh/Se Pw/Dst Incorp 11631-4 AgNaHZrPO
HumDW IndWPU SolConc OPour 39444-9 AgCl (?) Mpres Adh/Se Pw/Dst ! Incorp 73148-2 Ag-glass Mpres Fiber Pw/Dst Incorp 11631-4 AgNaHZrPO
Mpres FibText RTUSol Incorp 49403-34 AgCl/TiO2 Mpres Fiber Pw/Dst ! Incorp 73148-2 Ag-glass Mpres Coa/Fi Pw/Dst Incorp 11631-4 AgNaHZrPO
Mpres Adh/Se RTUSol Incorp 49403-36 AgCl/TiO2 Mpres PapCo Pw/Dst Incorp 73148-2 Ag-glass Mpres UpgCo Pw/Dst Incorp 11631-4 AgNaHZrPO
Mpres Misc RTUSol Incorp 49403-36 AgCl/TiO2 Mpres PntDyP Pw/Dst Incorp 73148-2 Ag-glass Mpres HVAC Pw/Dst Incorp 11631-4 AgNaHZrPO
Mpres PlFiMoP RTUSol Incorp 49403-36 AgCl/TiO2 Mpres PapCo Pw/Dst Incorp 73148-3 Ag-glass Mpres DrkWtr Pw/Dst Incorp 11631-4 AgNaHZrPO
Mpres FibText RTUSol Incorp 49403-36 AgCl/TiO2 Mpres PntDyP Pw/Dst Incorp 73148-3 Ag-glass Mpres Other Pw/Dst Incorp 11631-4 AgNaHZrPO
Mpres+ FibText RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres PlVPvc Pw/Dst Incorp 73148-4 Ag-glass Mpres PlVPvc Pw/Dst Incorp 74079-1 AgNaHZrPO
Mpres+ Adh/Se+ RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres Fiber Pw/Dst Incorp 73148-4 Ag-glass Mpres Adh/Se Pw/Dst Incorp 74079-1 AgNaHZrPO
Mpres+ Misc+ RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres PapCo Pw/Dst Incorp 73148-4 Ag-glass Mpres Fiber Pw/Dst Incorp 74079-1 AgNaHZrPO
Mpres+ PiFiMoP RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres PntDyP Pw/Dst Incorp 73148-4 Ag-glass Mpres Coa/Fi Pw/Dst Incorp 74079-1 AgNaHZrPO
Mpres+ Coa/Fi+ RTUSol+ Incorp+ 49403-38 AgCl/TiO2 Mpres PlVPvc Pw/Dst Incorp 73148-5 Ag-glass Mpres UpgCo Pw/Dst Incorp 74079-1 AgNaHZrPO
SPoSpa SPool ImprMat ESCart 53735-11 AgCl Mpres Fiber Pw/Dst Incorp 73148-5 Ag-glass Mpres HVAC Pw/Dst Incorp 74079-1 AgNaHZrPO
SPoSpa Spa ImprMat ESCart 53735-11 AgCl Mpres PapCo Pw/Dst Incorp 73148-5 Ag-glass Mpres DrkWtr Pw/Dst Incorp 74079-1 AgNaHZrPO
Mpres+ FibText RTUSol+ Incorp+ 84189-## AgCl/TiO2 Mpres PntDyP Pw/Dst Incorp 73148-5 Ag-glass Mpres Other Pw/Dst Incorp 74079-1 AgNaHZrPO
Mpres+ FibText RTUSol+ Incorp+ 87396-1 AgCl Mpres PlVPvc Pw/Dst Incorp 73148-6 Ag-glass Mpres PlVPvc Pw/Dst Incorp 74079-2 AgNaHZrPO

Mpres FibText SolConc Incorp 88088-1 AgCl Mpres Fiber Pw/Dst Incorp 73148-6 Ag-glass Mpres Adh/Se Pw/Dst Incorp 74079-2 AgNaHZrPO
Mpres+ Textls+ Pw/Dst+ MUP+ 88088-2 AgCl Mpres PapCo Pw/Dst Incorp 73148-6 Ag-glass Mpres Fiber Pw/Dst Incorp 74079-2 AgNaHZrPO
Mpres FibText RTUSol Incorp 88088-3 AgCl Mpres PntDyP Pw/Dst Incorp 73148-6 Ag-glass Mpres Coa/Fi Pw/Dst Incorp 74079-2 AgNaHZrPO
MdP&E+ DenWL+ Tablet Dissol+ 83315-1 AgCitrate Mpres PapCo Pw/Dst Incorp 73148-7 Ag-glass Mpres UpgCo Pw/Dst Incorp 74079-2 AgNaHZrPO
Mpres PlVPvc Pw/Dst Incorp 59441-8 AgSO4 Mpres PntDyP Pw/Dst Incorp 73148-7 Ag-glass Mpres HVAC Pw/Dst Incorp 74079-2 AgNaHZrPO
Mpres Adh/Se Pw/Dst Incorp 59441-8 AgSO4 Mpres PapCo Pw/Dst Incorp 82415-8 Ag-glass Mpres DrkWtr Pw/Dst Incorp 74079-2 AgNaHZrPO
Mpres Fiber Pw/Dst Incorp 59441-8 AgSO4 Mpres PntDyP Pw/Dst Incorp 82415-8 Ag-glass Mpres Other Pw/Dst Incorp 74079-2 AgNaHZrPO
Mpres Fiber Powder Incorp 59441-8 AgSO4 Mpres+ PlVPvc+ Pw/Dst+ Incorp+ 86106-1 Ag-glass Mpres+ NoLabl+ Pw/Dst+ Incorp+ 74079-3 AgNaHZrPO
Mpres PlaCoFi Powder Incorp 59441-8 AgSO4 Mpres+ Fiber Pw/Dst+ Incorp+ 86106-1 Ag-glass

Mpres Adh/Se Powder Incorp 59441-8 AgSO4 Mpres+ Coa/Fi+ Pw/Dst+ Incorp+ 86106-1 Ag-glass 

# Silver in ion-exchange resins

Spool SPool ImprMat ESCart 5185-498 AgNO3 Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 86106-1 Ag-glass 

# Area Sector Form Method Reg # Chemistry
HumDW WPurU ImprMat MUInc 69625-2 AgNO3 Mpres+ Misc+ Pw/Dst+ Incorp+ 86106-1 Ag-glass HumDW WPurU+ ImprMat+ MUInc+ 59454-3 Ag+/i-x
Agr+ CutFlwr SolConc+ Soak+ 72992-1 AgNO3 MdP&E+ DenWL+ ImprMat+ ESCart+ 83315-2 Ag+/i-x

MdP&E DenWL Tablet Dissol 79662-1 AgNO3

Mpres+ Textls+ SolConc+ Dp/Spry 84630-2 AgNO3
HumDW+ ImprFl+ SolConc+ MUInc+ 85531-2 AgNO3 

# Attachment 3: Usage of Silver Antimicrobials+: New since Preliminary Work Plan! : Corrected1.WaterTreatmentVeterinary FacilitiesMaterial Preservatives -- Fibers, Textiles, ApparelMaterial Preservatives -- Coatings and FilmsMaterial Preservatives -- Medical Devices/Algaecides for Swimming Pools and SpasAreaSectorFormMethodReg#ChemistryAreaSectorFormMethodReg#ChemistryAreaSectorFormMethodReg#ChemistryEquipment/Supplies (often FDA-regulated)AreaSectorFormMethodReg#ChemistryMdP&E VetRTUSol Spr/Mop84526-1 Col Ag/AgNO3Mpres+Fiber+Pw/Dst+ Incorp+87722-4Ag-clayMpresUpgCoPw/DstIncorp74079-2AgNaHZrPOAreaSectorFormMethodReg#ChemistrySpoolSPoolImprMatESCart67712-1Ag on cerMdP&E+ Vet+ SolConc+Spr/Mop84526-2Col Ag/AgNO3MpresFiberPw/DstIncorp11631-2AgNaHZrPO MpresCoSpPipPw/DstIncorp11631-2AgNaHZrPO MedDESAdh/Se+Pw/Dst+ Incorp+88165-1AgZeoliteSpoolSPoolImprMatESCart67712-5Ag on cerMdP&E+ Vet+ SolConc+Spr/Mop84545-4Col AgMpresFiberPw/DstIncorp11631-3AgNaHZrPO Mpres+Coa/Fi+Pw/Dst+ MUP+ 40810-23Ag-glassMedDESAdh/Se+Pw/Dst+ Incorp+88165-2AgZeoliteSpoolSpaImprMatESCart! 67712-15Ag on cerMdP&E VetRTUSol Spr/Mop71661-1AgIMpresFiberPw/DstIncorp11631-4AgNaHZrPO Mpres+Coa/Fi+Pw/Dst+ MUP+ 40810-26Ag-glassMedDESCoa/Fi+Pw/Dst+ Incorp+88165-1AgZeoliteSpoolSPoolSolConcOPour10324-18Col AgMdP&E VetRTUSol Spr/Mop72977-2SDCMpresFiberPw/DstIncorp74079-1AgNaHZrPO Mpres+Coa/Fi+Pw/Dst+ MUP+ 40810-19AgZn zeolMedDESCoa/Fi+Pw/Dst+ Incorp+88165-2AgZeoliteSpoolSPoolSolConcOPour57787-21 Col AgMdP&E VetRTUSol Spr/Mop72977-3SDCMpresFiberPw/DstIncorp74079-2AgNaHZrPOMedDESFiber+Pw/Dst+ Incorp+88165-2AgZeoliteSpool SPool SolConc OPour 68161-1 Col AgMdP&E Vet RTUSol Spr/Mop 72977-5 SDCMpres+ FibText Pw/Dst+ MUP+ 85249-2 Ag partclMaterial Preservatives -- Paper CoatingSpool SPool SolConc OPour 7124-101 Col AgMpres+ Textls+ Pw/Dst+ MUP+ 88088-2 AgClAreaSectorFormMethodReg #ChemistryMaterial Preservatives -- Drinking Water ContactSpool SPool SolConc OPour 3432-64 AgO3. Liquid Cleaners, Etc.Mpres+ Fiber+ Pw/Dst+ MUP+ 40810-23 Ag-glassMpres PapCo Pw/Dst Incorp 11631-5 Ag-glassAreaSectorFormMethodReg #ChemistrySpool Spa SolConc OPour 3432-71 AgOLiquid Antimicrobials, Disinfectants, SterilizersMpres+ Fiber+ Pw/Dst+ MUP+ 40810-26 Ag-glassMpres PapCo Pw/Dst Incorp 73148-1 Ag-glassMpres DrkWtrC Pw/Dst Incorp 11631-2 AgNaHZrPOSPoSpaSPoolImprMatESCart53735-11AgClAreaSectorFormMethodReg#ChemistryMpres+Fiber+Pw/Dst+ MUP+ 40810-19AgZn zeolMpresPapCoPw/DstIncorp73148-2Ag-glassMpresDrkWtrC Pw/DstIncorp11631-3AgNaHZrPOSPoSpaSpaImprMatESCart53735-11AgClPbbAcc HdSfc+ SolConc+Spr/Mop84545-11 Col AgMpresPapCoPw/DstIncorp73148-3Ag-glassMpresDrkWtrC Pw/DstIncorp11631-4AgNaHZrPOSpool SPool ImprMat ESCart 5185-498 AgNO3 ProUse EDecon+ SolConc+ Spr/Mop 84545-8 Col AgMaterial Preservatives, Plastics, Films, Etc.Mpres PapCo Pw/Dst Incorp 73148-4 Ag-glassMpres DrkWtrC Pw/Dst Incorp 74079-1 AgNaHZrPOProUse HdSfc+ SolConc+ Spr/Mop 84545-8 Col AgAreaSectorFormMethodReg #ChemistryMpres PapCo Pw/Dst Incorp 73148-5 Ag-glassMpres DrkWtrC Pw/Dst Incorp 74079-2 AgNaHZrPOHuman Drinking Water FiltersResPA+ HdSfc+ SolConc+ Spr/Mop 84526-2 Col AgMpres Pla/Cmp Pw/Dst ! Incorp 82691-2 Ag partclMpres PapCo Pw/Dst Incorp 73148-6 Ag-glassAreaSectorFormMethodReg #ChemistryResPA+ HdSfc+ SolConc+ Spr/Mop 84545-4 Col AgMpres+ Pla/Cmp Pw/Dst+ Incorp+ 83587-3 Ag partclMpres PapCo Pw/Dst Incorp 73148-7 Ag-glassMaterial Preservatives -- Dental Water LinesHumDW WPurU ImprMat ESCart 35900-2 Ag on A/CResPA Transp RTUSol Spr/Mop 73499-1 Col AgMpres+ Pla/Cmp Pw/Dst+ Incorp+ 84146-1 Ag partclMpres PapCo Pw/Dst Incorp 82415-8 Ag-glassAreaSectorFormMethodReg #ChemistryHumDW WPurU ImprMat ESCart 35900-3 Ag on A/CResPA HdSfc RTUSol Spr/Mop 73499-1 Col AgMpres+ PlFiMoP RTUSol+ Incorp+ 3090-225 AgCl/TiO2Mpres PapCo Pw/Dst ! Incorp 82415-3 AgZeoliteMpres DenWL Pw/Dst Incorp 40810-24 Ag-glassHumDW WPurU ImprMat ESCart 37589-2 Ag on A/CResPA HdSfc RTUSol Spr/Mop 73499-2 Col AgMpres PlFiMoP RTUSol Incorp 49403-36 AgCl/TiO2Mpres PapCo Pw/Dst Incorp 82415-2 AgZn zeolMpres DenWL Pw/Dst Incorp 40810-18 AgZn zeolHumDW WPurU ImprMatMUInc37589-4Ag on A/CResPAHdSfc RTUSol Spr/Mop84526-1 Col AgMpres+PlFiMoPRTUSol+ Incorp+49403-38AgCl/TiO2MpresPapCoPw/DstIncorp82415-1AgCu zeolHumDW WPurU ImprMat ESCart 37589-5 Ag on A/CResPA HdSfc RTUSol Spr/Mop 71661-1 AgIMpres PlaCoFi Powder Incorp 59441-8 AgSO4Mpres PapCo Pw/Dst Incorp 68317-1 AgApatiteMaterials Preservatives -- HVAC ComponentsHumDW WPurU ImprMatESCart37589-8Ag on A/CResPATransp RTUSol Spr/Mop71661-1AgIMpresPlVPvcPw/DstIncorp59441-8AgSO4MpresPapCoPw/DstIncorp68317-2AgApatiteAreaSectorFormMethodReg#ChemistryHumDW WPurU ImprMatESCart54625-2Ag on A/CResPAHdSfc RTUSol Spr/Mop67619-18SDCMpresPlFi Pw/DstIncorp11631-5Ag-glassMpresHVAC Pw/DstIncorp40810-24Ag-glassHumDW WPurU ImprMat ESCart 58295-1 Ag on A/CResPA HdSfc RTUSol Spr/Mop 72977-2 SDCMpres PlVPvc Pw/Dst ! Incorp 40810-24 Ag-glassMaterial Preservative -- Adhesives, SealantsMpres HVAC Pw/Dst Incorp 73148-1 Ag-glassHumDW WPurU ImprMat ESCart 58295-2 Ag on A/C ResPA HdSfc RTUSol Spr/Mop 72977-3 SDC Mpres PlVPvc Pw/Dst ! Incorp 40810-27 Ag-glassAreaSectorFormMethodReg #ChemistryMpres HVAC Pw/Dst ! Incorp 71227-1 AgZeoliteHumDW WPurU ImprMatESCart58295-3Ag on A/CResPA+ HdSfc+ RTUSol+ Spr/Mop72977-4SDCMpresPlVPvcPw/DstIncorp73148-1Ag-glassMPresAdh/SePw/DstIncorp82691-2Ag partclMpresHVAC Pw/DstIncorp40810-18AgZn zeolHumDW WPurU ImprMatMUInc62275-1Ag on A/CResPAHdSfc RTUSol Spr/Mop72977-5SDCMpresPlVPvcPw/DstIncorp73148-4Ag-glassMPresAdh/SePw/DstIncorp83587-3Ag partclMpresHVAC Pw/DstIncorp11631-2AgNaHZrPOHumDW WPurU ImprMatESCart68934-1Ag on A/CResPA+ HdSfc+ RTUSol+ Spray+75277-1 SDCMpresPlVPvcPw/DstIncorp73148-5Ag-glassMpres+Adh/Se+RTUSol+Incorp+3090-225AgCl/TiO2MpresHVAC Pw/DstIncorp11631-3AgNaHZrPOHumDW+ WPurU+ ImprMat+ESCart+ 70852-6Ag on A/CResPATransp RTUSol Spr/Mop67619-18SDCMpresPlVPvcPw/DstIncorp73148-6Ag-glassMpresAdh/SeRTUSol Incorp49403-36AgCl/TiO2MpresHVAC Pw/DstIncorp11631-4AgNaHZrPOHumDW WPurU ImprMatESCart74802-2Ag on A/CResPATransp RTUSol Spr/Mop72977-2SDCMpres+PlVPvc+ Pw/Dst+ Incorp+86106-1Ag-glassMpres+Adh/Se+RTUSol+Incorp+49403-38AgCl/TiO2MpresHVAC Pw/DstIncorp74079-1AgNaHZrPOHumDW WPurU ImprMatMUInc75456-1Ag on A/CResPATransp RTUSol Spr/Mop72977-3SDCMpresPlFiMoPPw/Dst ! Incorp82415-3AgZeoliteMpresAdh/SePowderIncorp59441-8AgSO4MpresHVAC Pw/DstIncorp74079-2AgNaHZrPOHumDW+ WPurU+ ImprMat+MUInc+ 75456-3Ag on A/CResPATransp RTUSol Spr/Mop72977-5SDCMpres+PlFiMoPPw/Dst+ Incorp+87731-1Ag zeolXMpresAdh/SePw/DstIncorp59441-8AgSO4HumDW+ WPurU+ ImprMat+ ESCart+ 85531-1 Ag on A/C MUP+ MUP+ SolConc+ MUP+ 70404-9 SDC Mpres+ PlFiMoP Pw/Dst+ Incorp+ 87731-2 Ag zeol X Mpres Adh/Se Pw/Dst Incorp 11631-5 Ag-glassMaterial Preservative -- Ceramics, GlassHumDW IndWPU SolConcOPour39444-9AgCl (?)MUP+ MUP+ SolConc+MUP+ 72977-1 SDCMpres+PlFiMoPPw/Dst+ Incorp+87722-1Ag-clayMpresAdh/SePw/DstIncorp40810-24Ag-glassAreaSectorFormMethodReg#ChemistryHumDW+ WPurU+ ImprMat+ESCart+ 88165-3AgZeoliteMpres+PlFiMoPPw/Dst+ Incorp+87722-2Ag-clayMpresAdh/SePw/Dst ! Incorp40810-27Ag-glassMpresCer/GlaPw/Dst ! Incorp82691-2Ag partclHumDW WPurU ImprMat MUInc 79630-2 Ag on cer4. Material PreservativesMpres+ PlFiMoP Pw/Dst+ Incorp+ 87722-3 Ag-clayMpres Adh/Se Pw/Dst ! Incorp 73148-2 Ag-glassMpres+ Cer/Gla Pw/Dst+ Incorp+ 83587-3 Ag partclHumDW WPurU ImprMat MUInc 71332-5 Ag on cerMaterial Preservatives -- Fibers, Textiles, ApparelMpres+ PlFiMoP Pw/Dst+ Incorp+ 87722-4 Ag-clayMpres+ Adh/Se+ Pw/Dst+ Incorp+ 86106-1 Ag-glassMpres+ Cer/Gla Pw/Dst+ Incorp+ 84146-1 Ag partclHumDW WPurU ImprMatMUInc69625-2AgNO3AreaSectorFormMethodReg#ChemistryMpresPlVPvcPw/Dst ! Incorp71227-1AgZeoliteMpresAdh/SePw/Dst ! Incorp82415-3AgZeoliteHumDW+ ImprFl+ SolConc+ MUInc+ 85531-2 AgNO3Mpres+ Fiber+ PltFib+! Incorp+ 84214-2 Ag on nylMpres PlVPvc Pw/Dst ! Incorp 71227-4 AgZeoliteMpres Adh/Se Pw/Dst ! Incorp 71227-1 AgZeoliteMaterial Preservatives -- MiscellaneousHumDW WPurU+ ImprMat+MUInc+ 59454-3Ag+/i-xMpres+Fiber+PltFib+! Incorp+84214-3Ag on nylMpresPlVPvcPw/Dst ! Incorp71227-5AgZeoliteMpresAdh/SePw/DstIncorp71227-4AgZeoliteAreaSectorFormMethodReg#ChemistryHumDW WPurU ImprMatMUInc68317-4AgApatiteMpresFiberPltFibr ! Incorp70927-1Ag on nylMpresPlVPvcPw/Dst ! Incorp71227-6AgZeoliteMpresAdh/SePw/Dst ! Incorp71227-5AgZeoliteMpres+Misc+ RTUSol+ Incorp+3090-225AgCl/TiO2HumDW+ WPurU+ Pw/Dst+ MUP+ 69096-3AgForFiltMpresFiberPltFibr ! Incorp70927-2Ag on nylMpresPlVPvcPw/Dst ! Incorp40810-18AgZn zeolMpresAdh/SePw/Dst ! Incorp71227-6AgZeoliteMpresMisc RTUSol Incorp49403-36AgCl/TiO2HumDW+ WPurU+ ImprMat+MUP+ 87256-1Ag on A/CMpresFiberPltFibr ! Incorp70927-3Ag on nylMpresPlVPvcPw/DstIncorp82415-1AgCu zeolMpresAdh/SePw/DstIncorp40810-18AgZn zeolMpres+Misc+ RTUSol+ Incorp+49403-38AgCl/TiO2HumDW+ WPurU+ Pw/Dst+ MUP+ 73667-5Ag on cerMpresFiberPltFibr ! Incorp70927-4Ag on nylMpresPlVPvcPw/DstIncorp11631-2AgNaHZrPO MpresAdh/SePw/Dst ! Incorp82415-2AgZn zeolMpres+Misc+ Pw/Dst+ Incorp+86106-1Ag-glassHumDW+ WPurU+ Pw/Dst+ MUP+ 73667-6Ag on cerMpresFiberPltFibr ! Incorp70927-5Ag on nylMpresPlVPvcPw/DstIncorp11631-3AgNaHZrPO MpresAdh/SePw/Dst ! Incorp71227-7AgCu zeolMpres+Misc+ Pw/Dst+ Incorp+87731-1Ag zeolXHumDW+ WPurU+ Pw/Dst+ MUP+ 73667-7Ag on cerMpres+Fiber+PltFibr+ Incorp+70927-6Ag on nylMpresPlVPvcPw/DstIncorp11631-4AgNaHZrPO MpresAdh/SePw/Dst ! Incorp82415-1AgCu zeolMpres+Misc+ Pw/Dst+ Incorp+87731-2Ag zeolXMpres Fiber PltFibr!! Incorp 84214-1 Ag on nylMpres PlVPvc Pw/Dst Incorp 74079-1 AgNaHZrPO Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 87731-1 Ag zeol XMpres+ Misc+ Pw/Dst+ Incorp+ 87722-4 Ag-clayHumidifiersMpres+ Textls+ PltFib+! Blend+ 85375-1 Ag on nylMpres PlVPvc Pw/Dst Incorp 74079-2 AgNaHZrPO Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 87731-2 Ag zeol XMpres+ NoLabl+ Pw/Dst+ Incorp+ 74079-3 AgNaHZrPOAreaSectorFormMethodReg#ChemistryMpresAdh/SePw/Dst ! Incorp82691-2Ag partclMpresPlVPvcPw/DstIncorp68317-1AgApatiteMpres+Adh/Se+Pw/Dst+ Incorp+87722-1Ag-clayMpresOtherPw/DstIncorp11631-2AgNaHZrPOResPA Humdfr ImprMat Place 79630-1 Ag on cer Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 83587-3 Ag partcl Mpres PlVPvc Pw/Dst Incorp 68317-2 AgApatite Mpres+ Adh/Se+ Pw/Dst+ Incorp+ 87722-3 Ag-clayMpres Other Pw/Dst Incorp 11631-3 AgNaHZrPOResPA+ Humdfr+ SolConc+Dilute+72977-6SDCMpres+Adh/Se+Pw/Dst+ Incorp+84146-1Ag partclMpres+PlFiMoPPw/Dst+ MUP+ 40810-23Ag-glassMpres+Adh/Se+Pw/Dst+ Incorp+87722-4Ag-clayMpresOtherPw/DstIncorp11631-4AgNaHZrPOMpres+ FibText Pw/Dst+ Incorp+ 85249-1 Ag partcl Mpres+ PlFiMoP Pw/Dst+ MUP+ 40810-26 Ag-glass Mpres Adh/Se Pw/Dst Incorp 11631-2 AgNaHZrPO Mpres Other Pw/Dst Incorp 74079-1 AgNaHZrPOIndustrial Cooling WaterMpres+ FibText RTUSol+ Incorp+ 3090-225 AgCl/TiO2Mpres+ PlFiMoP Pw/Dst+ MUP+ 40810-19 AgZn zeolMpres Adh/Se Pw/Dst Incorp 11631-3 AgNaHZrPO Mpres Other Pw/Dst Incorp 74079-2 AgNaHZrPOAreaSectorFormMethodReg#ChemistryMpresFibTextRTUSol Incorp49403-34AgCl/TiO2MpresAdh/SePw/DstIncorp11631-4AgNaHZrPO Mpres+Misc+ Pw/Dst+ MUP+ 40810-23Ag-glassIndCW+ CoolW+ SolConc+ Circ+ 84526-3 Col Ag/AgNO3 Mpres FibText RTUSol Incorp 49403-36 AgCl/TiO2Material Preservatives -- Coatings and FilmsMpres Adh/Se Pw/Dst Incorp 74079-1 AgNaHZrPO Mpres+ Misc+ Pw/Dst+ MUP+ 40810-26 Ag-glassIndCW+ CoolW+ SolConc+Circ+ 84526-4Col Ag/AgNO3Mpres+FibTextRTUSol+ Incorp+49403-38AgCl/TiO2AreaSectorFormMethodReg#ChemistryMpresAdh/SePw/DstIncorp74079-2AgNaHZrPO Mpres+Misc+ Pw/Dst+ MUP+ 40810-19AgZn zeolIndCW+ CoolW+ SolConc+ Circ+ 84526-5 Col Ag/AgNO3 Mpres+ FibText RTUSol+ Incorp+ 84189-## AgCl/TiO2Mpres Coatng Pw/Dst ! Incorp 82691-2 Ag partclMpres Adh/Se Pw/Dst Incorp 68317-1 AgApatiteMpres+ FibText RTUSol+ Incorp+ 87396-1 AgClMpres+ Coatng+ Pw/Dst+ Incorp+ 83587-3 Ag partclMpres Adh/Se Pw/Dst Incorp 68317-2 AgApatite5. AgriculturePaper/Pulp ManufactureMpres FibText RTUSol Incorp 88088-3 AgClMpres+ Coatng+ Pw/Dst+ Incorp+ 84146-1 Ag partclMpres+ Adh/Se+ Pw/Dst+ MUP+ 40810-23 Ag-glassAgricultural ApplicationsAreaSectorFormMethodReg#ChemistryMpresFibTextSolConcIncorp88088-1AgClMpres+Coa/Fi+RTUSol+ Incorp+49403-38AgCl/TiO2Mpres+Adh/Se+Pw/Dst+ MUP+ 40810-26Ag-glassAreaSectorFormMethodReg#ChemistryIndPap PuPap+ SolConc+ Circ+ 84526-3 Col Ag/AgNO3 Mpres Fiber Pw/Dst Incorp 59441-8 AgSO4Mpres Coa/Fi SolConc Incorp 707-313 Ion/pol cplx Mpres+ Adh/Se+ Pw/Dst+ MUP+ 40810-19 AgZn zeolAgrP&E HdSfc+ SolConc+ Spr/Mop 84545-11 Col AgIndPapPuPap+SolConc+Circ+ 84526-4Col Ag/AgNO3Mpres+Textls+SolConc+Dp/Spry84630-2AgNO3MpresCoa/FiSolConcIncorp464-783Ion/pol cplxAgrP&E Egg RTUSol Spray71661-1AgIIndPap PuPap+ SolConc+ Circ+ 84526-5 Col Ag/AgNO3 Mpres Fiber SolConc Incorp 707-313 Ion/pol cplx Mpres+ Coa/Fi+ Pw/Dst+ Incorp+ 86106-1 Ag-glassMaterials Preservatives -- Paints, Dyes, PigmentsAgrP&E Farm RTUSol Spray 71661-1 AgIMpres Fiber SolConc Incorp 464-783 Ion/pol cplxMpres Coa/Fi Pw/Dst ! Incorp 71227-1 AgZeoliteAreaSectorFormMethodReg #ChemistryAgrP&E Mshrm RTUSol Spray 71661-1 AgI2. MedicalMpres Fiber Pw/Dst Incorp 11631-5 Ag-glassMpres Coa/Fi Pw/Dst Incorp 71227-4 AgZeoliteMpres Paint Pw/Dst Incorp 11631-5 Ag-glassMedical Premises / Equipment -- Hard SurfacesMpres Fiber Pw/Dst Incorp 40810-24 Ag-glassMpres Coa/Fi Pw/Dst ! Incorp 71227-5 AgZeoliteMpres PntDyP Pw/Dst Incorp 73148-1 Ag-glassCut Flowers (suppress wilting from ethylene)AreaSectorFormMethodReg#ChemistryMpresFiberPw/Dst ! Incorp40810-27Ag-glassMpresCoa/FiPw/Dst ! Incorp71227-6AgZeoliteMpresPntDyPPw/DstIncorp73148-2Ag-glass[What "pest" is mitigated?]MdP&E HdSfc RTUSol Spr/Mop 73499-2 Col AgMpres Fiber Pw/Dst Incorp 73148-1 Ag-glassMpres UpgCo Pw/Dst ! Incorp 71227-1 AgZeoliteMpres PntDyP Pw/Dst Incorp 73148-3 Ag-glassAreaSectorFormMethodReg #ChemistryMdP&E HdSfc RTUSol Spr/Mop 84526-1 Col Ag/AgNO3 Mpres Fiber Pw/Dst ! Incorp 73148-2 Ag-glassMPres Coa/Fi Pw/Dst Incorp 40810-18 AgZn zeolMpres PntDyP Pw/Dst Incorp 73148-4 Ag-glassAgr+ CutFlwr SolConc+ Soak+ 72992-1 AgNO3MdP&E+ HdSfc+ SolConc+ Spr/Mop 84526-2 Col Ag/AgNO3 Mpres Fiber Pw/Dst Incorp 73148-4 Ag-glassMpres+ Coa/Fi+ Pw/Dst+ Incorp+ 87731-1 Ag zeol XMpres PntDyP Pw/Dst Incorp 73148-5 Ag-glassMdP&E+ HdSfc+ SolConc+ Spr/Mop 84545-11 Col AgMpres Fiber Pw/Dst Incorp 73148-5 Ag-glassMpres+ Coa/Fi+ Pw/Dst+ Incorp+ 87731-2 Ag zeol XMpres PntDyP Pw/Dst Incorp 73148-6 Ag-glassMdP&E+ HdSfc+ SolConc+Spr/Mop84545-4Col AgMpresFiberPw/DstIncorp73148-6Ag-glassMpres+Coa/Fi+Pw/Dst+ Incorp+87722-1Ag-clayMpresPntDyPPw/DstIncorp73148-7Ag-glassMdP&E HdSfc RTUSol Spr/Mop67619-18SDCMpres+FiberPw/Dst+ Incorp+86106-1Ag-glassMpres+Coa/Fi+Pw/Dst+ Incorp+87722-3Ag-clayMpresPntDyPPw/DstIncorp82415-8Ag-glassMdP&E HdSfc RTUSol Spr/Mop72977-2SDCMpresFiberPw/Dst ! Incorp82415-3AgZeoliteMpres+Coa/Fi+Pw/Dst+ Incorp+87722-4Ag-clayMpresPaintPw/Dst ! Incorp82415-3AgZeoliteMdP&E HdSfc RTUSol Spr/Mop 72977-3 SDCMpres Apparel Pw/Dst ! Incorp 82415-3 AgZeoliteMpres+ UpgCo+ Pw/Dst+ Incorp+ 87722-1 Ag-clayMpres+ Paint+ Pw/Dst+ Incorp+ 88165-1 AgZeoliteMdP&E HdSfc RTUSol Spr/Mop72977-5SDCMpresFiberPw/Dst ! Incorp71227-1AgZeoliteMpres+UpgCo+Pw/Dst+ Incorp+87722-3Ag-clayMpres+Paint+Pw/Dst+ Incorp+88165-2AgZeoliteMpres Fiber Pw/Dst ! Incorp 71227-5 AgZeoliteMpres Coa/Fi Pw/Dst Incorp 11631-2 AgNaHZrPO Mpres PntDyP Pw/Dst Incorp 82415-2 AgZn zeolDental Water LinesMpres Fiber Pw/Dst ! Incorp 71227-6 AgZeoliteMpres Coa/Fi Pw/Dst Incorp 11631-3 AgNaHZrPO Mpres+ Paint+ Pw/Dst+ Incorp+ 87722-3 Ag-clayAreaSectorFormMethodReg#ChemistryMpresFiberPw/DstIncorp40810-18AgZn zeolMpresCoa/FiPw/DstIncorp11631-4AgNaHZrPO Mpres+Paint+Pw/Dst+ Incorp+87722-4Ag-clayMdP&E DenWL RTUSol Circ 73499-2Col AgMpresFiberPw/DstIncorp71227-7AgCu zeolMpresCoa/FiPw/DstIncorp74079-1AgNaHZrPO MpresPntDyPPw/DstIncorp68317-1AgApatiteMdP&E DenWL SolConc Circ 75829-1 Col AgMpres Fiber Pw/Dst Incorp 82415-1 AgCu zeolMpres Coa/Fi Pw/Dst Incorp 74079-2 AgNaHZrPO Mpres PntDyP Pw/Dst Incorp 68317-2 AgApatiteMdP&E+ DenWL+ TabletDissol+ 83315-1AgCitrateMpres+Fiber+Pw/Dst+ Incorp+87731-1Ag zeolXMpresUpgCoPw/DstIncorp11631-2AgNaHZrPOMdP&E DenWL Tablet Dissol 79662-1 AgNO3Mpres+ Fiber+ Pw/Dst+ Incorp+ 87731-2 Ag zeol XMpres UpgCo Pw/Dst Incorp 11631-3 AgNaHZrPOMdP&E DenWL TabletDissol 84020-1 SDC (?)Mpres+Fiber+Pw/Dst+ Incorp+87722-1Ag-clayMpresUpgCoPw/DstIncorp11631-4AgNaHZrPOMdP&E+ DenWL+ ImprMat+ESCart+ 83315-2Ag+/i-xMpres+Fiber+Pw/Dst+ Incorp+87722-3Ag-clayMpresUpgCoPw/DstIncorp74079-1AgNaHZrPOAttachment 4: Categories for Silver Antimicrobials

# List of Abbreviations

AREA

Agr Agriculture AgrP&E Agricultural Premises & Equipment

HumDW Human Drinking Water

IndCW Industrial Cooling Water
IndPap Industrial Paper

MUP Manufacturing Use Product

MdP&E Medical Premises & Equipment

MedDES Medical Devices/Equipment/ Supplies

MPres Materials Preservative

PubAcc Public Access Sites

ProUse Professional Use

ResPA Residential and Public Access

Premises SPoSpa Swimming Pools & Spas Spool Swimming Pools



# SECTOR

Adh/Se Adhesives & Sealants

Adhe Adhesives
Apprl Apparel

Cer/Gla Ceramics & Glasses CoSpPip Coatings for Fire Sprinkler Piping

Coa/Fi Coatings & Films Coatng Coatings

CoolW Cooling Water

CutFlwr Cut Flowers

DenWL Dental Water Lines

DrkWtr Drinking Water Contact
Egg Egg Grading & Products

Establlishments

Edecon Decontamination of Equipment

Farm Farm Premises

FibText Fibers & Textiles

Fiber Fibers

HVAC HVAC articles

HdSfc Hard Surfaces

Humdfr Humidifiers ImprAC Impregnation of Filter Media

IndvWPU Individual Water Purification

Units

MUP Manufacturing Use Product

Misc Miscellaneous

Mshrm Mushroom Farm Premises Other Other

Paint Paint PapCo Paper Coating

PlFi Plastics & Films

PlFiMoP Plastics, Films, Molded Plastics

PlVPvc Plastics, Vinyl, PVC Products Pla/Cmp Plastics & Plastic Composites

PlaCoFi Plastics, Coatings, Films,

Laminates PntDyP Paints, Dyes & Pigments
PuPap Pulp & Paper

SPool Swimming Pools Spa Spas

Textl Textiles
Transp Transportation UpgCo Upgraded Coatings

Vet Veterinary

WPurU Water Purification Units



# FORM

ImprMat Impregnated Material

PltFibr+ Plated Fiber

Powder Powder

Pw/Dst Powder/Dust

RTUSol Ready-to-Use Solution

SolConc Soluble Concentrate

Tablet Tablet



# METHOD

Blend Blending

Circ Circulation

Dilute Dilution

Dissol Dissolution Dp/Spry Dip/Spray

ESCart Enclosed System Cartridge
Incorp Incorporation

MUInc Manufacturing Use Incorporation

MUP Manufacturing Use Product

OPour Open Pour

Place Place

Soak Soak Spr/Mop Spray/Mop Spray Spray