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                                                                    Exhibit 10.2

                            GENOME THERAPEUTICS CORP.

                        RESTRICTED STOCK AWARD AGREEMENT


     Pursuant to this Restricted Stock Award Agreement between the undersigned
and Genome Therapeutics Corp. (the "Company"), the undersigned is advised that
the Board of Directors of the Company (the "Board") has voted to award the
undersigned 20,000 shares of common stock of the Company, $.10 par value
("Stock"), subject to the restrictions and conditions set forth below. The date
of this Award, set forth above, is hereinafter referred to as the "date of
grant". Please note that in order for this Agreement to be valid, the
undersigned must execute two copies and forward one copy to Joseph A. Pane, Vice
President, Human Resources, at Genome Therapeutics Corp., 100 Beaver Street,
Waltham, Massachusetts 02154, not later than [30 DAYS AFTER DATE OF THE AWARD].

     In consideration of the Company's transferring to the undersigned the
shares of Stock provided for herein, the undersigned hereby agrees with the
Company as follows:

1.   The shares of Stock issued by the undersigned hereunder pursuant to this
     Restricted Stock Award Agreement shall not be sold, transferred, pledged,
     assigned or otherwise encumbered or disposed of except as provided below.

2.   In the event the undersigned ceases to be employed by the Company for any
     reason other than death or disability (as hereinafter defined), the Stock
     issued hereunder, less any shares that have previously vested, shall be
     immediately forfeited to the Company. In the event the undersigned
     involuntarily ceases to be employed by the Company for any reason other
     than for cause, the Company, at its discretion, may distribute all of the
     unvested Stock issued hereunder. The undersigned shall deliver to the
     Company one or more stock powers, endorsed in blank, with respect to shares
     of Stock under this award that have not yet vested. For purposes of this
     Agreement, "disability" shall mean the inability of the undersigned to
     perform the services normally rendered due to any physical or mental
     impairment that can be expected to be of either permanent or indefinite
     duration, as determined by the Board or one of its committees on the basis
     of appropriate medical evidence and that results in the termination of
     employment of the undersigned; PROVIDED, that if the undersigned has
     entered into an employment agreement with the Company, the term of which
     has not expired at the time a determination concerning disability hereunder
     is to be made, disability for purposes of this Agreement shall have the
     meaning, if any, attributed to "permanent disability" in such employment
     agreement.

3.   The shares of Stock issued hereunder shall vest in accordance with the
     provisions of this Paragraph 3, as follows:


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     as to 50% of the shares on December 16, 2000, and as to the remaining 50%
     of the shares on December 16, 2001.

provided in each case that the undersigned is then, and since the date of grant
has continuously been, employed by the Company. In the event of a Change of
Control of the Company, all shares of Stock issued hereunder that have not
previously been forfeited shall immediately vest, provided that the undersigned
remains employed by the Company at least 120 days following such Change of
Control. For purposes of the Agreement, "Change of Control" shall mean (i) the
acquisition of 35% or more of the outstanding common stock of the Company by a
person, group, or entity; (ii) a merger or other business combination in which
the Company is not the surviving corporation; or (iii) diminution of employment
status in either responsibility or compensation as a direct result of a Change
in Control.

4.   Unvested shares shall be represented by certificates, which shall be held
     by the Company, containing the following legend:

     THE TRANSFERABILITY OF THIS CERTIFICATE AND THE SHARES OF STOCK REPRESENTED
     HEREBY ARE SUBJECT TO THE TERMS AND CONDITIONS (INCLUDING FORFEITURE) OF A
     RESTRICTED STOCK AWARD AGREEMENT ENTERED INTO BETWEEN THE REGISTERED OWNER
     AND GENOME THERAPEUTICS CORP. COPIES OF SUCH AGREEMENT ARE ON FILE IN THE
     OFFICES OF GENOME THERAPEUTICS CORP.

As soon as practicable following the vesting of any such shares the Company
shall cause a new certificate or certificates covering such shares, without the
aforesaid legend, to be issued and delivered to the undersigned, subject to the
payment by the undersigned by cash or other means acceptable to the Company of
any withholding taxes due in connection with such vesting.

5.   The undersigned shall be entitled to any and all dividends or other
     distributions paid with respect to all shares of Stock issued hereunder
     which have not been forfeited or otherwise disposed of and shall be
     entitled to vote any such shares; PROVIDED, HOWEVER, that any property
     (other than cash) distributed with respect to a share of Stock (the
     "associated share") issued hereunder, including without limitation a
     distribution of Stock by reason of a stock dividend, stock split or
     otherwise, or a distribution of other securities with respect to an
     associated share, shall be subject to the restrictions of this Restricted
     Stock Award Agreement in the same manner and for so long as the associated
     share remains subject to such restrictions, and shall be promptly forfeited
     to the Company if and when the associated share is so forfeited.

6.   The undersigned understands that once a certificate has been delivered to
     the undersigned in respect of shares of Stock issued hereunder which have
     vested, the


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     undersigned will be free to sell the shares of Stock evidenced by such
     certificate, subject to applicable requirements of federal and state
     securities laws.

7.   The undersigned expressly acknowledges that the award or vesting of the
     shares of Stock issued hereunder will give rise to "wages" subject to
     withholding. The undersigned expressly acknowledges and agrees that his
     rights hereunder are subject to his paying to the Company in cash (or by
     such other means as may be acceptable to the Company in its discretion,
     including, if the Board or one of its committees so determines, by the
     delivery of previously issued Stock or shares of Stock issued hereunder)
     all taxes required to be withheld in connection with such award or vesting.

     IN WITNESS WHEREOF, each of the Company and the undersigned hereby executes
this agreement as of the date first written above.

GENOME THERAPEUTICS CORP.



By:    ___________________________                 ____________________________
Title:                                             Name: Richard D. Gill