CHEMICAL NAME CAS NO.HAPNO.IARCWOE mg/m3 SOURCEEPAWOE 1/(ug/m3) MOA SOURCE mg/kg/d SOURCEEPAWOE 1/(mg/kg/d) MOA SOURCEAcetaldehyde 75-07-0 1 2B 0.009IRISB2 0.0000022IRISAcetamide 60-35-5 2 2B 0.00002CALAcetonitrile 75-05-8 3 0.06IRISInIAcetophenone 98-86-2 4 DAcrolein 107-02-8 6 3 0.00002IRISInIAcrylamide 79-06-1 7 2A 0.006IRISLH 0.0001 M*IRISAcrylic acid 79-10-7 8 3 0.001IRISAcrylonitrile 107-13-1 9 2B 0.002IRISB1 0.000068IRISAllyl chloride 107-05-1 10 3 0.001IRISC 0.000006CALAniline 62-53-3 12 3 0.001IRISB2 0.0000016CALAntimony compounds 7440-36-0 173Antimony pentoxide 1314-60-9 173Antimony potassium tartrate 304-61-0 173Antimony tetroxide 1332-81-6 173Antimony trioxide 1309-64-4 173 2B 0.0002IRISArsenic compounds 7440-38-2 174 1 0.000015CALA 0.0043IRISArsenic pentoxide 1303-28-2 174Arsine 7784-42-1 174 0.00005IRISBenzene 71-43-2 15 1 0.03IRISCH 0.0000078IRISBenzidine 92-87-5 16 1 0.01P-CALA 0.067 M*IRISBenzotrichloride 98-07-7 17 2B B2Benzyl chloride 100-44-7 18 2B B2 0.000049CALBeryllium compounds 7440-41-7 175 1 0.00002IRISLH 0.0024IRISBeryllium oxide 1304-56-9 175Biphenyl 92-52-4 19 DBis(2-ethylhexyl)phthalate 117-81-7 20 2B 0.01P-CALB2 0.0000024CALBis(chloromethyl)ether 542-88-1 21 1 A 0.062IRISBromoform 75-25-2 22 3 B2 0.0000011IRIS1,3-Butadiene 106-99-0 23 1 0.002IRISCH 0.00003IRISCadmium compounds 7440-43-9 176 1 0.00001ATSDRB1 0.0018IRIS0.0005IRISB1Captan 133-06-2 26 3 B2Carbaryl 63-25-2 27Carbon disulfide 75-15-0 28 0.7IRISTable 1. Prioritized Chronic Dose-Response Values forScreening Risk Assessments (5/9/2014)CHRONIC INHALATION CHRONIC ORALTable 1. Prioritized Chronic Dose-Response Values (5/9/2014).Revisions since 05/07/2012 are shown in red.CAS NO.= Chemical Abstracts Services number for the compound.HAP NO.=Position of the compound on the HAP list in the Clean Air Act (112[b][2]). "999"denotes substances under consideration for listing.Sources:IRIS = Integrated Risk Information System; ATSDR = US Agency forToxic Substances and Disease Registry; D-ATSDR = draft ATSDR; CA =California EPA; P-CAL = Proposed CAL; HEAST = EPA Health EffectsAssessment TablesIARC WOE= weight-ofevidence forcarcinogenicity inhumans (1 -carcinogenic; 2A -probably carcinogenic;2B - possiblycarcinogenic; 3 - notclassifiable; 4 -probably notcarcinogenic).EPA WOE(2005 Guidelines) = weight of evidence forcarcinogenicity under 2005 EPA cancer guidelines: CH -carcinogenic to humans; LH - likely to be carcinogenic; SE -suggestive evidence of carcinogenic potential; InI -inadequate information to assess carcinogenic potential; NH -not likely to be carcinogenic).EPAMOA(2005 Guidelines) = mode of action for carcinogenicity:M* - mutagenic and early life data lacking; age-dependentadjustment factors should be applied when assessing risk forages younger than 16 years per 2005 SupplementalGuidance.[See Table1 notes.]EPA WOE(1986 Guidelines) = weightof-evidence for carcinogenicity underthe 1986 EPA cancer guidelines: A -human carcinogen; B1 - probablecarcinogen, limited human evidence;B2 - probable carcinogen, sufficientevidence in animals; C - possiblehuman carcinogen; D - not classifiableE - evidence of noncarcinogenicity.CANCERCANCERNONCANCERNONCANCERPage 1 of 8CHEMICAL NAME CAS NO.HAPNO.IARCWOE mg/m3 SOURCEEPAWOE 1/(ug/m3) MOA SOURCE mg/kg/d SOURCEEPAWOE 1/(mg/kg/d) MOA SOURCETable 1. Prioritized Chronic Dose-Response Values forScreening Risk Assessments (5/9/2014)CHRONIC INHALATION CHRONIC ORALTable 1. Prioritized Chronic Dose-Response Values (5/9/2014).Revisions since 05/07/2012 are shown in red.CAS NO.= Chemical Abstracts Services number for the compound.HAP NO.=Position of the compound on the HAP list in the Clean Air Act (112[b][2]). "999"denotes substances under consideration for listing.Sources:IRIS = Integrated Risk Information System; ATSDR = US Agency forToxic Substances and Disease Registry; D-ATSDR = draft ATSDR; CA =California EPA; P-CAL = Proposed CAL; HEAST = EPA Health EffectsAssessment TablesIARC WOE= weight-ofevidence forcarcinogenicity inhumans (1 -carcinogenic; 2A -probably carcinogenic;2B - possiblycarcinogenic; 3 - notclassifiable; 4 -probably notcarcinogenic).EPA WOE(2005 Guidelines) = weight of evidence forcarcinogenicity under 2005 EPA cancer guidelines: CH -carcinogenic to humans; LH - likely to be carcinogenic; SE -suggestive evidence of carcinogenic potential; InI -inadequate information to assess carcinogenic potential; NH -not likely to be carcinogenic).EPAMOA(2005 Guidelines) = mode of action for carcinogenicity:M* - mutagenic and early life data lacking; age-dependentadjustment factors should be applied when assessing risk forages younger than 16 years per 2005 SupplementalGuidance.[See Table1 notes.]EPA WOE(1986 Guidelines) = weightof-evidence for carcinogenicity underthe 1986 EPA cancer guidelines: A -human carcinogen; B1 - probablecarcinogen, limited human evidence;B2 - probable carcinogen, sufficientevidence in animals; C - possiblehuman carcinogen; D - not classifiableE - evidence of noncarcinogenicity.CANCERCANCERNONCANCERNONCANCERCarbon tetrachloride 56-23-5 29 2B 0.1IRISLH 0.000006IRISChloramben 133-90-4 32Chlordane 57-74-9 33 2B 0.0007IRISLH 0.0001IRIS0.0005IRISLH 0.35IRISChlorine 7782-50-5 34 0.00015ATSDRChloroacetic acid 79-11-8 352-Chloroacetophenone 532-27-4 36 0.00003IRISChlorobenzene 108-90-7 37 1CALDChlorobenzilate 510-15-6 38 3 B2 0.000078HEASTChloroform 67-66-3 39 2B 0.098ATSDRLHChloroprene 126-99-8 41 2B 0.02IRISLH 0.0003 M*IRISChromium (III) compounds 16065-83-1 177 3 InIChromium (VI) compounds 18540-29-9 177 1 0.0001IRISCH 0.012IRISChromium (VI) trioxide, chromic acid mist 11115-74-5 177 1 0.000008IRISCobalt compounds 7440-48-4 178 2B 0.0001ATSDRCoke Oven Emissions 8007-45-2 179 A 0.00062M*IRISm-Cresol 108-39-4 44 Co-Cresol 95-48-7 43 Cp-Cresol 106-44-5 45 CCresols (mixed) 1319-77-3 42 0.6CALCCumene 98-82-8 46 2B 0.4IRISInICyanazine 21725-46-2 180 CCyanide compounds 57-12-5 180 DAcetone cyanohydrin 75-86-5 180 0.01HEASTCalcium cyanide 592-01-8 180Copper cyanide 544-92-3 180Cyanogen 460-19-5 180 0.0008IRISCyanogen bromide 506-68-3 180Cyanogen chloride 506-77-4 180Ethylene cyanohydrin 109-78-4 180Hydrogen cyanide 74-90-8 180 0.0008IRISPotassium cyanide 151-50-8 180 0.0008IRISPotassium silver cyanide 506-61-6 180 0.0008IRISSilver cyanide 506-64-9 180Page 2 of 8CHEMICAL NAME CAS NO.HAPNO.IARCWOE mg/m3 SOURCEEPAWOE 1/(ug/m3) MOA SOURCE mg/kg/d SOURCEEPAWOE 1/(mg/kg/d) MOA SOURCETable 1. Prioritized Chronic Dose-Response Values forScreening Risk Assessments (5/9/2014)CHRONIC INHALATION CHRONIC ORALTable 1. Prioritized Chronic Dose-Response Values (5/9/2014).Revisions since 05/07/2012 are shown in red.CAS NO.= Chemical Abstracts Services number for the compound.HAP NO.=Position of the compound on the HAP list in the Clean Air Act (112[b][2]). "999"denotes substances under consideration for listing.Sources:IRIS = Integrated Risk Information System; ATSDR = US Agency forToxic Substances and Disease Registry; D-ATSDR = draft ATSDR; CA =California EPA; P-CAL = Proposed CAL; HEAST = EPA Health EffectsAssessment TablesIARC WOE= weight-ofevidence forcarcinogenicity inhumans (1 -carcinogenic; 2A -probably carcinogenic;2B - possiblycarcinogenic; 3 - notclassifiable; 4 -probably notcarcinogenic).EPA WOE(2005 Guidelines) = weight of evidence forcarcinogenicity under 2005 EPA cancer guidelines: CH -carcinogenic to humans; LH - likely to be carcinogenic; SE -suggestive evidence of carcinogenic potential; InI -inadequate information to assess carcinogenic potential; NH -not likely to be carcinogenic).EPAMOA(2005 Guidelines) = mode of action for carcinogenicity:M* - mutagenic and early life data lacking; age-dependentadjustment factors should be applied when assessing risk forages younger than 16 years per 2005 SupplementalGuidance.[See Table1 notes.]EPA WOE(1986 Guidelines) = weightof-evidence for carcinogenicity underthe 1986 EPA cancer guidelines: A -human carcinogen; B1 - probablecarcinogen, limited human evidence;B2 - probable carcinogen, sufficientevidence in animals; C - possiblehuman carcinogen; D - not classifiableE - evidence of noncarcinogenicity.CANCERCANCERNONCANCERNONCANCERSodium cyanide 143-33-9 180 0.0008IRISThiocyanic acid, 2-(benzothiazolylthio) methyl est 21564-17-0 180Zinc cyanide 557-21-1 1802,4-D, salts and esters 94-75-7 47DDE 72-55-9 48 B2 B2 0.34IRIS1,2-Dibromo-3-chloropropane 96-12-8 51 2B 0.0002IRISB2 0.002CALDibutylphthalate 84-74-2 52 Dp-Dichlorobenzene 106-46-7 53 2B 0.8IRISC 0.000011CAL3,3'-Dichlorobenzidine 91-94-1 54 2B B2 0.00034CALDichloroethyl ether 111-44-4 55 3 B2 0.00033IRIS1,3-Dichloropropene 542-75-6 56 2B 0.02IRISLH 0.000004IRISDichlorvos 62-73-7 57 2B 0.0005IRISB2Diesel engine emissions DIESEL EMIS. 999 0.005IRISLHDiethanolamine 111-42-2 58 0.003CAL3,3'-Dimethoxybenzidine 119-90-4 61 2B B2p-Dimethylaminoazobenzene 60-11-7 62 2B 0.0013CAL3,3'-Dimethylbenzidine 119-93-7 63 B2Dimethyl formamide 68-12-2 65 3 0.03IRISN,N-dimethylaniline 121-69-7 59 31,1-Dimethylhydrazine 57-14-7 66 2B B22,4-dinitrophenol 51-28-5 702,4-Dinitrotoluene 121-14-2 71 2B 0.007P-CALB2 0.000089CAL2,4/2,6-Dinitrotoluene (mixture) 25321-14-6 71 2B B21,4-Dioxane 123-91-1 72 2B0.03IRISLH0.000005IRIS1,2-Diphenylhydrazine 122-66-7 73 B2 0.00022IRISEpichlorohydrin 106-89-8 74 2A 0.001IRISB2 0.0000012IRIS1,2-Epoxybutane 106-88-7 75 0.02IRISEthyl acrylate 140-88-5 76 2B B2Ethyl benzene 100-41-4 77 2B 1IRISD 0.0000025CALEthyl carbamate 51-79-6 78 2A 0.00029 M*CALEthyl chloride 75-00-3 79 3 10IRISEthylene dibromide 106-93-4 80 2A 0.009IRISLH 0.0006IRISEthylene dichloride 107-06-2 81 2B 2.4ATSDRB2 0.000026IRISPage 3 of 8CHEMICAL NAME CAS NO.HAPNO.IARCWOE mg/m3 SOURCEEPAWOE 1/(ug/m3) MOA SOURCE mg/kg/d SOURCEEPAWOE 1/(mg/kg/d) MOA SOURCETable 1. Prioritized Chronic Dose-Response Values forScreening Risk Assessments (5/9/2014)CHRONIC INHALATION CHRONIC ORALTable 1. Prioritized Chronic Dose-Response Values (5/9/2014).Revisions since 05/07/2012 are shown in red.CAS NO.= Chemical Abstracts Services number for the compound.HAP NO.=Position of the compound on the HAP list in the Clean Air Act (112[b][2]). "999"denotes substances under consideration for listing.Sources:IRIS = Integrated Risk Information System; ATSDR = US Agency forToxic Substances and Disease Registry; D-ATSDR = draft ATSDR; CA =California EPA; P-CAL = Proposed CAL; HEAST = EPA Health EffectsAssessment TablesIARC WOE= weight-ofevidence forcarcinogenicity inhumans (1 -carcinogenic; 2A -probably carcinogenic;2B - possiblycarcinogenic; 3 - notclassifiable; 4 -probably notcarcinogenic).EPA WOE(2005 Guidelines) = weight of evidence forcarcinogenicity under 2005 EPA cancer guidelines: CH -carcinogenic to humans; LH - likely to be carcinogenic; SE -suggestive evidence of carcinogenic potential; InI -inadequate information to assess carcinogenic potential; NH -not likely to be carcinogenic).EPAMOA(2005 Guidelines) = mode of action for carcinogenicity:M* - mutagenic and early life data lacking; age-dependentadjustment factors should be applied when assessing risk forages younger than 16 years per 2005 SupplementalGuidance.[See Table1 notes.]EPA WOE(1986 Guidelines) = weightof-evidence for carcinogenicity underthe 1986 EPA cancer guidelines: A -human carcinogen; B1 - probablecarcinogen, limited human evidence;B2 - probable carcinogen, sufficientevidence in animals; C - possiblehuman carcinogen; D - not classifiableE - evidence of noncarcinogenicity.CANCERCANCERNONCANCERNONCANCEREthylene glycol 107-21-1 82 0.4CALEthylene oxide 75-21-8 84 1 0.03CALB1 0.000088CALEthylene thiourea 96-45-7 85 3 0.003P-CALB2 0.000013CALEthylidene dichloride (1,1-Dichloroethane) 75-34-3 86 0.5HEASTC 0.0000016CALFormaldehyde 50-00-0 87 1 0.0098ATSDRB1 0.000013IRISDiethylene glycol monobutyl ether 112-34-5 181 0.02HEASTDiethylene glycol monoethyl ether 111-90-0 181Ethylene glycol ethyl ether 110-80-5 181 0.2IRISEthylene glycol ethyl ether acetate 111-15-9 181 0.3CALEthylene glycol methyl ether 109-86-4 181 0.02IRISEthylene glycol methyl ether acetate 110-49-6 181 0.09CALHeptachlor 76-44-8 88 2B B2 0.0013IRIS0.0005IRISB2 4.5IRISHexachlorobenzene 118-74-1 89 2B 0.003P-CALB2 0.00046IRIS0.0008IRISB2 1.6IRISHexachlorobutadiene 87-68-3 90 3 0.09P-CALC 0.000022IRISHexachlorocyclopentadiene 77-47-4 91 0.0002IRISNHHexachlorodibenzo-p-dioxin, mixture 19408-74-3 187 B2 1.3IRISB2 6200IRISHexachloroethane 67-72-1 92 2B 0.03IRISLHHexamethylene-1,6-diisocyanate 822-06-0 93 0.00001IRISn-Hexane 110-54-3 95 0.7IRISInIHydrazine 302-01-2 96 2B 0.0002CALB2 0.0049IRISHydrochloric acid 7647-01-0 97 3 0.02IRISHydrofluoric acid 7664-39-3 98 0.014CALHydrogen sulfide 7783-06-4 999 0.002IRISInIHydroquinone 123-31-9 99Isophorone 78-59-1 100 2CALCLead compounds 7439-92-1 182 2B 0.00015OAQPSB2 B2Tetraethyl lead 78-00-2 182 0.0000001IRISLindane (gamma-HCH) 58-89-9 101 2B 0.0003P-CALB2-C 0.00031CAL0.0003IRISB2-C 1.1CALalpha-Hexachlorocyclohexane (a-HCH) 319-84-6 101 2B 0.02P-CALB2 0.0018IRIS0.008ATSDRB2 6.3IRISbeta-Hexachlorocyclohexane (b-HCH) 319-85-7 101 2B 0.002P-CALC 0.00053IRISC 1.8IRIStechnical Hexachlorocyclohexane (HCH) 608-73-1 101 2B B2 0.00051IRISB2 1.8IRISMaleic anhydride 108-31-6 102 0.0007CALManganese compounds 7439-96-5 1830.0003ATSDRDPage 4 of 8CHEMICAL NAME CAS NO.HAPNO.IARCWOE mg/m3 SOURCEEPAWOE 1/(ug/m3) MOA SOURCE mg/kg/d SOURCEEPAWOE 1/(mg/kg/d) MOA SOURCETable 1. Prioritized Chronic Dose-Response Values forScreening Risk Assessments (5/9/2014)CHRONIC INHALATION CHRONIC ORALTable 1. Prioritized Chronic Dose-Response Values (5/9/2014).Revisions since 05/07/2012 are shown in red.CAS NO.= Chemical Abstracts Services number for the compound.HAP NO.=Position of the compound on the HAP list in the Clean Air Act (112[b][2]). "999"denotes substances under consideration for listing.Sources:IRIS = Integrated Risk Information System; ATSDR = US Agency forToxic Substances and Disease Registry; D-ATSDR = draft ATSDR; CA =California EPA; P-CAL = Proposed CAL; HEAST = EPA Health EffectsAssessment TablesIARC WOE= weight-ofevidence forcarcinogenicity inhumans (1 -carcinogenic; 2A -probably carcinogenic;2B - possiblycarcinogenic; 3 - notclassifiable; 4 -probably notcarcinogenic).EPA WOE(2005 Guidelines) = weight of evidence forcarcinogenicity under 2005 EPA cancer guidelines: CH -carcinogenic to humans; LH - likely to be carcinogenic; SE -suggestive evidence of carcinogenic potential; InI -inadequate information to assess carcinogenic potential; NH -not likely to be carcinogenic).EPAMOA(2005 Guidelines) = mode of action for carcinogenicity:M* - mutagenic and early life data lacking; age-dependentadjustment factors should be applied when assessing risk forages younger than 16 years per 2005 SupplementalGuidance.[See Table1 notes.]EPA WOE(1986 Guidelines) = weightof-evidence for carcinogenicity underthe 1986 EPA cancer guidelines: A -human carcinogen; B1 - probablecarcinogen, limited human evidence;B2 - probable carcinogen, sufficientevidence in animals; C - possiblehuman carcinogen; D - not classifiableE - evidence of noncarcinogenicity.CANCERCANCERNONCANCERNONCANCERMercuric chloride 7487-94-7 184 C 0.0003IRISCMercury (elemental) 7439-97-6 184 3 0.0003IRISD DMethyl mercury 22967-92-6 184 C 0.0001IRISCPhenylmercuric acetate 62-38-4 1840.00008IRISMethanol 67-56-1 10320IRISMethoxychlor 72-43-5 104 3 D 0.005IRISDMethyl bromide 74-83-9 105 0.005IRISDMethyl chloride 74-87-3 106 3 0.09IRISInIMethyl chloroform (1,1,1-Trichloroethane) 71-55-6 107 5IRISInIMethyl isobutyl ketone 108-10-1 111 2B 3IRISInIMethyl isocyanate 624-83-9 112 0.001CALMethyl methacrylate 80-62-6 113 0.7IRISEMethyl tert-butyl ether 1634-04-4 114 3 3IRIS2.6E-07CAL4,4'-Methylene bis(2-chloroaniline) 101-14-4 115 1 B2 0.00043CALMethylene chloride 75-09-2 116 2B 0.6IRISLH 1E-08 M*IRISMethylene diphenyl diisocyanate 101-68-8 117 0.0006IRISInI4,4'-Methylenedianiline 101-77-9 118 2B 0.02CAL0.00046CALNaphthalene 91-20-3 119 0.003IRISC 0.000034CALNickel compounds 7440-02-0 186 1 0.00009ATSDRANickel oxide 1313-99-1 186Nickel refinery dust NI_DUST 186 A 0.00024IRISNickel subsulfide 12035-72-2 186 A 0.00048IRISNitrobenzene 98-95-3 120 2B 0.009IRISLH 0.00004IRIS2-Nitropropane 79-46-9 123 2B 0.02IRISB2 0.0000056OAQPSNitrosodimethylamine 62-75-9 125 2A B2 0.014 M*IRISN-Nitrosomorpholine 59-89-2 126 2B 0.0019CALParathion 56-38-2 127 3 CPolychlorinated biphenyls 1336-36-3 136 2A B2 0.0001IRISB2 2IRISAroclor 1016 12674-11-2 1360.00007IRISAroclor 1254 11097-69-1 1360.00002IRISPentachloronitrobenzene 82-68-8 128 3 CPentachlorophenol 87-86-5 129 2B 0.1P-CALB2 0.0000051CALPhenol 108-95-2 130 3 0.2CALInIPage 5 of 8CHEMICAL NAME CAS NO.HAPNO.IARCWOE mg/m3 SOURCEEPAWOE 1/(ug/m3) MOA SOURCE mg/kg/d SOURCEEPAWOE 1/(mg/kg/d) MOA SOURCETable 1. Prioritized Chronic Dose-Response Values forScreening Risk Assessments (5/9/2014)CHRONIC INHALATION CHRONIC ORALTable 1. Prioritized Chronic Dose-Response Values (5/9/2014).Revisions since 05/07/2012 are shown in red.CAS NO.= Chemical Abstracts Services number for the compound.HAP NO.=Position of the compound on the HAP list in the Clean Air Act (112[b][2]). "999"denotes substances under consideration for listing.Sources:IRIS = Integrated Risk Information System; ATSDR = US Agency forToxic Substances and Disease Registry; D-ATSDR = draft ATSDR; CA =California EPA; P-CAL = Proposed CAL; HEAST = EPA Health EffectsAssessment TablesIARC WOE= weight-ofevidence forcarcinogenicity inhumans (1 -carcinogenic; 2A -probably carcinogenic;2B - possiblycarcinogenic; 3 - notclassifiable; 4 -probably notcarcinogenic).EPA WOE(2005 Guidelines) = weight of evidence forcarcinogenicity under 2005 EPA cancer guidelines: CH -carcinogenic to humans; LH - likely to be carcinogenic; SE -suggestive evidence of carcinogenic potential; InI -inadequate information to assess carcinogenic potential; NH -not likely to be carcinogenic).EPAMOA(2005 Guidelines) = mode of action for carcinogenicity:M* - mutagenic and early life data lacking; age-dependentadjustment factors should be applied when assessing risk forages younger than 16 years per 2005 SupplementalGuidance.[See Table1 notes.]EPA WOE(1986 Guidelines) = weightof-evidence for carcinogenicity underthe 1986 EPA cancer guidelines: A -human carcinogen; B1 - probablecarcinogen, limited human evidence;B2 - probable carcinogen, sufficientevidence in animals; C - possiblehuman carcinogen; D - not classifiableE - evidence of noncarcinogenicity.CANCERCANCERNONCANCERNONCANCERp-Phenylenediamine 106-50-3 131Phosgene 75-44-5 132 0.0003IRISInIPhosphine 7803-51-2 133 0.0003IRISInIPhosphorus, white 7723-14-0 134 0.00007P-CALDPhthalic anhydride 85-44-9 135 0.02CALPolybrominated biphenyls 59536-65-1 187 2B B2 0.000007HEASTB2 8.9HEASTAcenaphthene 83-32-9 187 3 D 0.06IRISDAcenaphthylene 206-96-8 187 D D2-Aminoanthraquinone 117-79-3 187 3 0.0000094CAL0.033CALAnthracene 120-12-7 187 3 D 0.3IRISDBenz(a)anthracene 56-55-3 187 2B B2 0.00011CALB2 1.2CALBenzo(b)fluoranthene 205-99-2 187 2B B2 0.00011CALB2 1.2CALBenzo[j]fluoranthene 205-82-3 187 2B 0.00011CAL1.2CALBenzo(k)fluoranthene 207-08-9 187 2B B2 0.00011CALB2 1.2CALBenzo(g,h,i)perylene 191-24-2 187 3 D DBenzo(a)pyrene 50-32-8 187 1 B2 0.0011 M*CALB2 7.3 M*IRISBenzo(e)pyrene 192-97-2 187 3Carbazole 86-74-8 187 2B B2 B2 0.02HEASTbeta-Chloronaphthalene 91-58-7 1870.08IRISChrysene 218-01-9 187 2B B2 0.000011CALB2 0.12CALDibenz[a,h]acridine 226-36-8 187 2B 0.00011CAL1.2CALDibenz[a,j]acridine 224-42-0 187 2A 0.00011CAL1.2CALDibenz(a,h)anthracene 53-70-3 187 2A B2 0.0012 M*CALB2 4.1 M*CAL7H-Dibenzo[c,g]carbazole 194-59-2 187 2B 0.0011CAL12CALDibenzo[a,e]pyrene 192-65-4 187 3 0.0011CAL12CALDibenzo[a,h]pyrene 189-64-0 187 2B 0.011CAL120CALDibenzo[a,i]pyrene 189-55-9 187 2B 0.011CAL120CALDibenzo[a,l]pyrene 191-30-0 187 2A 0.011CAL120CAL7,12-Dimethylbenz(a)anthracene 57-97-6 187 0.071 M*CAL250 M*CAL1,6-Dinitropyrene 42397-64-8 187 2B 0.011CAL120CAL1,8-Dinitropyrene 42397-65-9 187 2B 0.0011CAL12CALFluoranthene 206-44-0 187 3 D 0.04IRISDFluorene 86-73-7 187 3 D 0.04IRISDPage 6 of 8CHEMICAL NAME CAS NO.HAPNO.IARCWOE mg/m3 SOURCEEPAWOE 1/(ug/m3) MOA SOURCE mg/kg/d SOURCEEPAWOE 1/(mg/kg/d) MOA SOURCETable 1. Prioritized Chronic Dose-Response Values forScreening Risk Assessments (5/9/2014)CHRONIC INHALATION CHRONIC ORALTable 1. Prioritized Chronic Dose-Response Values (5/9/2014).Revisions since 05/07/2012 are shown in red.CAS NO.= Chemical Abstracts Services number for the compound.HAP NO.=Position of the compound on the HAP list in the Clean Air Act (112[b][2]). "999"denotes substances under consideration for listing.Sources:IRIS = Integrated Risk Information System; ATSDR = US Agency forToxic Substances and Disease Registry; D-ATSDR = draft ATSDR; CA =California EPA; P-CAL = Proposed CAL; HEAST = EPA Health EffectsAssessment TablesIARC WOE= weight-ofevidence forcarcinogenicity inhumans (1 -carcinogenic; 2A -probably carcinogenic;2B - possiblycarcinogenic; 3 - notclassifiable; 4 -probably notcarcinogenic).EPA WOE(2005 Guidelines) = weight of evidence forcarcinogenicity under 2005 EPA cancer guidelines: CH -carcinogenic to humans; LH - likely to be carcinogenic; SE -suggestive evidence of carcinogenic potential; InI -inadequate information to assess carcinogenic potential; NH -not likely to be carcinogenic).EPAMOA(2005 Guidelines) = mode of action for carcinogenicity:M* - mutagenic and early life data lacking; age-dependentadjustment factors should be applied when assessing risk forages younger than 16 years per 2005 SupplementalGuidance.[See Table1 notes.]EPA WOE(1986 Guidelines) = weightof-evidence for carcinogenicity underthe 1986 EPA cancer guidelines: A -human carcinogen; B1 - probablecarcinogen, limited human evidence;B2 - probable carcinogen, sufficientevidence in animals; C - possiblehuman carcinogen; D - not classifiableE - evidence of noncarcinogenicity.CANCERCANCERNONCANCERNONCANCERIndeno(1,2,3-cd)pyrene 193-39-5 187 2B B2 0.00011CALB2 1.2CAL3-Methylcholanthrene 56-49-5 187 0.0063 M*CAL22 M*CAL5-Methylchrysene 3697-24-3 187 2B 0.0011CAL12CAL1-Methylnaphthalene 90-12-0 1870.07ATSDR2-Methylnaphthalene 91-57-6 187 InI 0.04ATSDRInI5-Nitroacenaphthene 602-87-9 187 2B 0.000037CAL0.13CAL6-Nitrochrysene 7496-02-8 187 2B 0.011CAL120CAL2-Nitrofluorene 607-57-8 187 2B 0.000011CAL0.12CAL1-Nitropyrene 5522-43-0 187 2B 0.00011CAL1.2CAL4-Nitropyrene 57835-92-4 187 2B 0.00011CAL1.2CALOctabromodiphenyl ether 32536-52-0 187 D 0.003IRISDPhenanthrene 85-01-8 187 3 D DPyrene 129-00-0 187 3 D 0.03IRISD1,3-Propane sultone 1120-71-4 137 2B 0.00069CALPropionaldehyde 123-38-6 139 0.008IRISInIPropoxur 114-26-1 140 B2Propylene dichloride 78-87-5 141 0.004IRISB2Propylene oxide 75-56-9 142 2B 0.03IRISB2 0.0000037IRISQuinoline 91-22-5 144 LHSelenium compounds 7782-49-2 189 3 0.02CALDHydrogen selenide 7783-07-5 189 0.00008P-CALSelenious acid 7783-00-8 189 DSelenium dioxide 7446-08-4 189 0.02CALSelenium disulfide 7488-56-4 189 0.02CALSelenium sulfide 7446-34-6 189 0.02CALB2Selenourea 630-10-4 189Styrene 100-42-5 146 2B 1IRISStyrene oxide 96-09-3 147 2A 0.006P-CAL2,3,7,8-Tetrachlorodibenzo-p-dioxin 1746-01-6 148 1 4E-08CALB2 33EPA ORD7E-10IRISB2 150000EPA ORD1,1,2,2-Tetrachloroethane 79-34-5 149 3LHTetrachloroethene 127-18-4 150 2A 0.04IRISLH 2.6E-07IRISTitanium tetrachloride 7550-45-0 151 0.0001ATSDRToluene 108-88-3 152 3 5IRISInIPage 7 of 8CHEMICAL NAME CAS NO.HAPNO.IARCWOE mg/m3 SOURCEEPAWOE 1/(ug/m3) MOA SOURCE mg/kg/d SOURCEEPAWOE 1/(mg/kg/d) MOA SOURCETable 1. Prioritized Chronic Dose-Response Values forScreening Risk Assessments (5/9/2014)CHRONIC INHALATION CHRONIC ORALTable 1. Prioritized Chronic Dose-Response Values (5/9/2014).Revisions since 05/07/2012 are shown in red.CAS NO.= Chemical Abstracts Services number for the compound.HAP NO.=Position of the compound on the HAP list in the Clean Air Act (112[b][2]). "999"denotes substances under consideration for listing.Sources:IRIS = Integrated Risk Information System; ATSDR = US Agency forToxic Substances and Disease Registry; D-ATSDR = draft ATSDR; CA =California EPA; P-CAL = Proposed CAL; HEAST = EPA Health EffectsAssessment TablesIARC WOE= weight-ofevidence forcarcinogenicity inhumans (1 -carcinogenic; 2A -probably carcinogenic;2B - possiblycarcinogenic; 3 - notclassifiable; 4 -probably notcarcinogenic).EPA WOE(2005 Guidelines) = weight of evidence forcarcinogenicity under 2005 EPA cancer guidelines: CH -carcinogenic to humans; LH - likely to be carcinogenic; SE -suggestive evidence of carcinogenic potential; InI -inadequate information to assess carcinogenic potential; NH -not likely to be carcinogenic).EPAMOA(2005 Guidelines) = mode of action for carcinogenicity:M* - mutagenic and early life data lacking; age-dependentadjustment factors should be applied when assessing risk forages younger than 16 years per 2005 SupplementalGuidance.[See Table1 notes.]EPA WOE(1986 Guidelines) = weightof-evidence for carcinogenicity underthe 1986 EPA cancer guidelines: A -human carcinogen; B1 - probablecarcinogen, limited human evidence;B2 - probable carcinogen, sufficientevidence in animals; C - possiblehuman carcinogen; D - not classifiableE - evidence of noncarcinogenicity.CANCERCANCERNONCANCERNONCANCER2,4-Toluene diamine 95-80-7 153 2B B2 0.0011CAL2,4/2,6-Toluene diisocyanate mixture (TDI) 26471-62-5 154 2B 0.00007IRIS0.000011CALo-Toluidine 95-53-4 155 1 B2 0.000051CALToxaphene 8001-35-2 156 2B B2 0.00032IRISB2 1.1IRIS1,2,4-Trichlorobenzene 120-82-1 157 0.2HEASTD1,1,2-Trichloroethane 79-00-5 158 3 0.4P-CALC 0.000016IRISTrichloroethylene 79-01-6 159 2A 0.002IRISCH 0.0000041 M*IRIS2,4,5-Trichlorophenol 95-95-4 1602,4,6-Trichlorophenol 88-06-2 161 B2 0.0000031IRISTriethylamine 121-44-8 162 0.007IRISTrifluralin 1582-09-8 163 3 C 0.0075IRISC 0.0077IRISUranium compounds 7440-61-1 188Uranium, insoluble salts URANINSOLS 188 0.0008ATSDRUranium, soluble salts URANSOLS 188 0.00004ATSDRVinyl acetate 108-05-4 165 2B 0.2IRISVinyl bromide 593-60-2 166 2A 0.003IRISB2 0.000032HEASTVinyl chloride 75-01-4 167 1 0.1IRISCH 0.0000088IRISVinylidene chloride 75-35-4 168 3 0.2IRISSEm-Xylene 108-38-3 171o-Xylene 95-47-6 170Xylenes (mixed) 1330-20-7 169 3 0.1IRISInIPage 8 of 8