BIOSKETCHES FOR DCM

- NMP PEER REVIEW PANELISTS

Dr. Gary Ginsberg (Chair) is a toxicologist at the Connecticut Department of Public Health
within the Division of Environmental and O ccupational Health Assessment. He has responsibility for human health risk assessments conducted within the state government. Dr. Ginsberg serves as adjunct faculty at the Yale School of Public Health and is an Assistant
Clinical Professor at the University of Connecticut School of Community Medicine. He is currently a member of the National Academy of Sciences committee reviewing inorganic arsenic and served on two previous NAS committees (Human Biomonitoring, 2007; USEPA Risk Methods which produce d Science and Decisions, 2009). He was first author of a manuscript that
won best paper of the year award from the Society of Toxicology Risk Asse ssment Specialty Section, 2009. Dr. Ginsberg was a member of USEPA’s Children’s Health Protection Advisory Committee until 2009 and is currently a member of USEPA’s Science Advisory Bo ard. He has participated on expert review panels for state governments in Minnesota, New Jersey , California
and Massachusetts. He was an Oak Ridge Institute for Science and Education (ORISE) fellow with USEPA’s National Center for Environmental Assessmen t from 201 0 to 2012. He has published in the areas of early life stage vulnerability, pharmacokinetic modeling, genetic polymorphisms, metabolism in aging populations, fish consumption advisories and environmental risk assessment. Dr. Ginsberg's toxicology experienc e has involved a variety of settings: basic research, teaching, working within the pesticide and consulting industries, and now working in public health. Dr. Ginsberg is also co

- author of a book on toxics for the lay public, “What’s Toxic, What’s Not:” Ber kley Books, December 2006.

Dr. Thomas W. Armstrong is the Principal Investigator since 2008 at his sole proprietor consulting company, TWA8HR Occupational Hy giene Consulting, LLC . Dr. Armstrong
received his B .A. in Chemistry, M .S. in Environmental Health , and Ph

. D

. in Environmental Engineer ing, all from Drexel University in Philadelphia, Pennsylvania

. He currently has an Adjunct Professor appointment at the Drexel Unive rsity School of Public Health. Before he
retired from ExxonMobil Biomedical Sciences in 2008, his last position there was as Senior
Scientific A ssociate in Exposure Sciences. While at ExxonMobil, he developed exposure assessment strategies for and provided support to multiple epidemiology studies, including work
under contract to the Univers ity of Colorado to support multiple general population epidemiology inve stigations in Shanghai, China. Also, w hile at ExxonMobil, Dr. Armstrong served on the company’s internal occupational exposure limit committee and published a method for adjusting expo sure limits to extended work schedules. His ongoing research activities include exposure assessment for epidemiology studies, mathematical methods to estimate exposures to
chemicals and quantitative risk assessments for Legione lla and Legionnaires’ disease

. He has 30 peer reviewed publications, has contributed multiple chapters to three books and has provided

p eer reviews to eight journals. Dr. Armstrong has presented on diverse topics at symposia in the
United States and abroad. He was the lead instructor for American Industrial Hygiene Association (AIHA) professional development courses on mathematical modeling to assess chemical exposures, and Monte Carlo Simulation techniques in exposure assessment, and has taught in other courses, including a review of toxicology for industrial hygienists. He remains active in AIHA risk assessment, epidemiology and exposure assessment committee activities. Dr. Armstrong was a member of two National Academy of Sciences committees that conducted reviews of and completed r eports on risk assessments for two national biocontainmentlaboratories. In addition, he provided support to a N ational I nstitute for O ccupational S afety and

H ealth (NIOSH) review of the institute’s occupational exposure assessment strategy, and served

on a NIOSH National Occupatio nal Research Agenda committee. He also participated in several panels on EPA children’s health issues.

Dr. Frank A. Barile is Professor of Applied and Clinical Toxicology in the Department of Pharmaceutical Sciences, St. John's University College of Pharmacy and Health Sciences, New York. He received his Ph.D. in Toxicology (1982) at St. John's University. He completed post

doctoral fellowships at the Albert Einstein College of Medicine, Bronx, NY, and Columbia University, NY. In 1984, he was appointed Assistant Professor in the Department of Health Sciences at City University of NY. Sixteen years later he rejoined St. John's University in the Department of Pharmaceutical Sciences. Dr. Barile holds memberships in the U.S. Society of Toxicology, the American Association for the Advancement of Science, and the New York Academy of Sciences. He was elected President of the In Vitro & Alternative Methods Specialty Section of the U.S. Society of Toxicology (2005

- 2008) and was recently el ected VP

- elect for the Dermal Toxicology Specialty Section (2013

- 2014), followed by President. He is the recipient of
the U.S. Public Health Service Medallion from the Director of the NIEHS, Dr. Linda Birnbaum (June, 2009). Dr. Barile is the recipient of PHS research grants from the National Institutes of Health (NIGMS) for the last 20 years, as well as from the Alternative Research & Development Foundation (Jenkinton, PA) and the International Foundation for Ethical Research (Chicago, IL). Dr. Barile has authored approximately 75 papers and abstracts in peer

- reviewed biomedical and toxicology journals, as well as five books and three chapters, including Clinical Toxicology: Principles and Mechanisms, 2nd edition, 2010 (Inform a HealthCare, UK) and Principles of Toxicology Testing, 2nd edition, 2013 (CRC Press, FL). Recently published articles describe the development of in vitro ocular toxicity testing methods for detecting irritant and corrosive properties of chemicals ( J. Pha rmacological Toxicological Methods , 2010) and highlight epigenetic mechanisms using trace metals in embryonic stem cells ( Toxicology Letters

, 2012).
Dr. Barile serves on the editorial boards of Toxicology In Vitro (2007

- present) and J. Pharmacological & T

oxicological Methods (2008

- present). He is currently Editor

- in

- Chief of Toxicology In Vitro (2012

- present). He continues fundamental research on the cytotoxic effects of environmental chemicals on cultured human and mammalian embryonic stem cells.

Dr. Jam es V. Bruckner is currently Professor of Pharmacology and Toxicology in the Department of Pharmaceutical and Biomedical Sciences, Colleg e of Pharmacy of the University of Georgia (UGA). He organized and directed the UGA Interdisciplinary Toxicology Graduat e Program in Toxicology for 15 years. Prior to that time he held a tenured faculty position at the University of Texas Medical School at Houston. He received his B.S. degree in pharmacy and M.S. degree in toxicology from the University of Texas in Austin. His Ph.D. in toxicology was awarded by the University of Michigan. Dr. Bruckner's primary areas of expertise are general toxicology, toxicokinetics (TK) and human health risk assessment. His primary research focus is on the toxicology and TK of volatile organic chemical contaminants of drinking water, drug

chemical interactions at environmental exposure levels, metabolic and toxicokinetic bases for susceptibility of children to chemicals, and physiological modeling of solvents and pyrethroid
insecticides. The relevance of experimental designs to health risks of "real life" chemical exposures is of particular interest. Research funding for the past 35 years has consistently come from federal agencies for toxicology studies of problems of national concern. The primaryfunding sources have been the U.S. EPA, DOE, CDC and Air Force. Dr. Bruckner has published

more than 200 journal articles, book chapters and abstracts. Many of these papers focus on the toxicology, TK and PBPK modeling. He has served on a v ariety of expert panels and committees for the U.S. EPA, NIEHS, NASA, Air Force, ATSDR/CDC,FDA and National Academy of Sciences (NAS). The NAS appointments have included, among others, the Committees on Safe Drinking Water, Pesticides in Diets and Infant s and Children; Acute Exposure Guideline Levels; Health and Safety Consequences of Child Labor; Use of Third Party Pesticide Toxicity Research with Human Participants; and Contaminated Drinking Water at Camp Lejeune. Such work has frequently involved asses sment of health risks to pop ulations living in the proximity of military chemical and nuclear disposal sites (e.g., Camp Lejeune, NC; Fort Detrick, MD; Savannah River site, SC) . Dr. Bruckner is currently a member of the ACGIH TLV chemical substances panel and the NAS Committee on Toxicology.

Dr. Anneclaire J. De Roos is Associate Professor of Environmental and Occupational Health in the Drexel University School of Public Heal th in Philadelphia, PA. She ear ned a B.A. (Geography/E cosystems) from the Univers ity of California at Los Ange les, MPH (Epidemiology/B iostatistics) from the University of California at Berkeley, and a Ph

. D

. (E pidemiology) in the year 2000 from the University of North Carolina at Chapel Hill

. Her research interests and experience are pr imarily in the study of occupational and environmental exposures to chemicals and radiation as risk factors for cancer, autoimmune diseases and intermediate biologic effects

. Dr. De Roos’ dissertation research focused on parental occupational exposures as risk factors for childhood cancer in their offspring . From 2000

– 2002, Dr. De Roos trained as a postdoctoral fellow in the Division of Cancer Epidemiology and
Genetics of the National Cancer Institute (NCI) , where she gained experience in studies of genetic determinants of disease and intermediate biologic effects (immune function, inflammation) of environmental exposures

. She was a member of the faculty at the University of Washington (UW) and Fred Hutchinson Cancer Research Center in Seattle, WA from 2003

– 2012, where her research focused on environmental risk factors for non

- Hodgkin lymphoma,
leukemias and other cancers, including : workplace e xposures (pesticides, solvents); persistent

org anic pollutants (PCBs, dioxins); and point sources of pollution (indu strial facilities, traffic)

. Dr. De Roos has been a member of the International Lymphoma Epidemiology (InterLymph ) Consortium since 2005, and currently is funded by the National Institute of Environmental Health Sciences (NIEHS) to conduct a consortium

- bas ed evaluation of occupational solvent exposure as a potential cause of multiple myeloma

. At the UW, Dr. De Roos taught courses in cancer epidemiology, environmental and occupational epidemiology, public health in the media, and advanced epidemiologic metho ds

. In her current position at Drexel, Dr. De Roos is developing a new masters’ level course in environmental risk assessment

. She serves as a frequent reviewer for occupational and environmental health journals, most notably as an
editorial review board m ember for Environmental Health Perspectives

. She has published more than 90 refereed research articles, authored 7 book chapters, and made numerous invited presentations at national and international conferences . Dr. De Roos also has served on several expert committees in recent years, including those reviewing formaldehyde for NIEHS’s Report on Carcinogens and the trichloroethylene (TCE) health assessment document for the USEPA

.Dr. Annette Guiseppi

- Elie is a Principal Consultant on Exposure and Risk Assessment issues

for the DuPont Company. Also, she is an Adjunct Associate Professor in Environmental Engineering and Earth Sciences at Clemson University. She is a Fellow of the American Institute of Medical and Biological Engineers. She has served on a number of scientific entities in her role as technical expert and advocate for the use of sound scientific principles and data in conducting environmental health risk assessments. These organizations include the USEPA Science Advisory B oard, the Mickey Leland Center National Urban Air Toxics Research Center, the International Programme on Chemical Safety’s Planning Committee on Harmonization of Exposure Assessment, and the American Chemistry Council’s Strategic Science Team, where
she cu rrently leads the Exposure Subcommittee. She is past Chair of the American Industrial Heath Council’s Environmental Health Risk Assessment Committee. Her expertise is in the areas of site and risk assessment, specifically, exposure assessments and includes environmental fate and transport processes. Dr. Guiseppi

- Elie has conducted environmental site assessments and risk assessments both in the US and internationally. Her doctoral research focused on the fate and transport of dioxins in the environment. Her current research interests are in the areas of integrated/cumulative exposure (including exposomics) and risk assessment and the relationship between indoor, outdoor and personal air exposures. Her work experience includes service on the faculty at Drexel University, service to Mobil Oil and the Exxon Corporation. Dr. Guiseppi

- Elie received the B.Sc. degree in Chemistry and Zoology and the M.Sc. in Crop Production Entomology from the University of the West Indies (UWI), Trinidad in 1977 and 1979, respective ly. She received a M.Sc. degree in Pollution and Environmental Control from the University of Manchester Institute of Science and Technology (UMIST), England in 1980 and her Ph.D. in Civil Engineering from the University of Maryland College Park (UMCP), US A in
1987.

Dr. Ronald D. Hood is Principal of Ronald D. Hood and Associates, Toxicology Consultants. He also is Professor Emeritus of Biological Sciences, having retired from the faculty of the Cell, Molecular, and Developmental Biology Section of the Department of Biological Sciences of the University of Alabama after 32 years of service, and he has been an Adjunct Professor of Public Health, School of Public Health, University of Alabama at Birmingham. Dr. Hood received his
Ph.D. from Purdue University in 1969 in Reproductive Physiol ogy and joined the faculty of the University of Alabama as an Assistant Professor. He was promoted to the rank of Professor by 1978, and he also served as Interim Department Chair from July 1996 to August, 1997. In addition, Dr. Hood was Consultant in Envi ronmental Medicine for the U.S. Veterans Administration, Office of Medicine and Surgery, Agent Orange Special Projects Office (off site), during 1983, and a Special Consul tant, Science Advisory Board, EPA, from 1983 through 1993.
He has served as a consult ant to pharmaceutical, chemical, and biotech companies, trade associations, federal and state regulatory agencies, and law firms since 1978. Dr. Hood presented toxicology training courses to regulatory personnel of H ealth Canada annually from 2006 to
2011. Dr. Hood has served as a member of the editorial boards of Fundamental and Applied Toxicology and Toxicological Sciences , and he was an ad hoc member of EPA’s Food Quality Protection Act Science Review Board. Dr. Hood has participated in workshops and exp ert panels to provide expertise on developmental toxicity and risk assessment, and he was inducted as a Fellow of the Academy of Toxicological Sciences. Dr . Hood has authored, coauthored or edited more than 100 publications (research articles, book chapter s and books) in the areas of developmental and reproductive toxicology. Dr. Hood ’ s most recent edited book isDevelopmental and Reproductive Toxicology, a Practical Approach

, Third Edition , published in

2012, by the Informa Healthcare division of CRC Press . Dr. Hood has been active in the Teratology Society, chairing the Membership, Education , Constitution/Bylaws, and Webs ite
committees. He also has been active in the Reproductive and Developmental Toxicology Specialty Section of the Society of Toxicology, and he has served as their newsletter editor.

Dr. John C. Kissel is currently Professor of Environmental and Occupational Health Sciences at
the University of Washington in Seattle, where he has been a member of the faculty since 1990. He held a prior position in the School of Public and Environmental Affairs at Indiana University. Dr. Kissel holds a Ph.D. in Civil/Environmental Engineering from Stanford University and is a registered professional engineer. Dr. Kissel's research interests generally involve human exposure assessment, with emphasis on exposures related to waste management, agricultural and residential use of pesticides, and consume r products. He is particularly interested in probabilistic prediction of aggregate exposure and reconciliation of model predictions with observed biomarker data. Dr. Kissel and his students have produced multiple papers describing human exposure to soil that are listed as “key studies” in US EPA’s Exposure Factors Handbook . Dr. Kissel is a former President and Councilor of the International Society of Exposure Science and also served one term as chair of the Exposure Assessment Specialty Group within the Society for Risk Analysis. He was a member of a National Academy of Sciences Committee that evaluated Superfund

- related remediation of mining and smelting related contamination in the Coeur d’Alene Basin in Idaho and a reviewer of the WHO environmental h ealth criteria document on Dermal Exposure, which will be published soon. Dr. Kissel has served as an ad hoc member of US EPA's FIFRA Science Advisory Panel on multiple occasions and is currently a member of EPA’s Human Studies Review Board. His recent r esearch activities have been funded by US EPA, US DOE, NIOSH and the Washington State Departments of Ecology and Health.

Dr. Philip J. Lupo is an epidemiologist and Assistant Professor of Pediatrics in the Section of Hematology

- Oncology at Baylor College of Medicine. He earned his BS degree from Houston Baptist University, Houston, Texas (Biology and Political Science); his MPH from University of Texas School of Public Health (Disease Control); and his PhD degree from University of Texas
School of Public Health (Epidemiology). His doctoral research was focused on the association between hazardous air pollutants and birth defects, as well as epidemiologic methods related to these studies (e.g., exposure misclassification due to residential mobility and etio logic heterogeneity among composite phenotypes). This research has led to several published manuscripts and ongoing collaborations with investigators at the Texas Birth Defects Registry and other birth defects surveillance systems. For his post

- doctoral tr aining, Dr. Lupo served as a Faculty Associate in the Human Genetics Center at University of Texas School of Public Health in order to gain additional training in the design and analysis of family

- based association studies (case

- parent triads) to assess no t only inherited genetic effects, but also novel genetic mechanisms such as maternally

- mediated genetic effects, genomic imprinting, and gene

environment interactions. Dr. Lupo has developed an expertise in genetic and environmental
determinants of birth d efects and childhood cancer. Dr. Lupo also serves as an Associate Member of the Texas Center for Birth Defects Research and Prevention. Aside from being a
funded collaborator with the Centers for Disease Control

- funded National Birth Defects
Prevention Stu dy, Dr. Lupo is the recipient of the American Heart Association’s Beginning
Grant

- in

- Aid to evaluate prenatal exposure to environmental toxicants and the risk of congenitalheart defects. Dr. Lupo has also recently received a grant from the National Instit utes of Health

to explore the role of air toxics and neighborhood environment on the risk of oral clefts. Additionally, Dr. Lupo is currently collaborating with other researchers and clinicians to develop studies examining the role of genes and prenatal ex posures on the development of childhood cancer, as well as the identification of novel risk factors for long

- term complications of childhood cancer therapies. As a member of the Children’s Oncology Group (COG) Epidemiology Committee, Dr. Lupo is working wi th investigators to build a research program in the epidemiology of rhabdomyosarcoma. He serves as a member of the American Heart Association’s Genomics & Translational Epidemiology & Observational Epidemiology Population Science 2 Peer Review Committee an d has been a reviewer for 21 journals. He has published 45 refereed publications, authored 3 book chapters, and made several invited speeches and presentations at national and international conferences.

Dr. Ernest E. McConnell D.V.M., M.S. (Path), DACVP, DABT is the president of ToxPath, Inc., a private consulting firm in Raleigh, N orth C arolina . He received his D

. V

. M

. from T he Ohio State University, a n M

. S

. in P athology from Michigan State University, and completed a residency in comparative pathology at the Armed Forces Institute of Pathology, Walter

- R eed Army Medical Center. He spent 13 years in the U .S. Air Force and 14 in the US Public Health Service. Gene's positions in the government included an assignment at the Veterina ry Research Institute, Onderstepoort, South Africa, Aerospace Medical Research Lab., Wright

- Patterson Air Force Base, Ohio and National Institute of Environmental Health Sciences (NIEHS), where he was Chief of the Chemical Pathology Branch and Director of the National Toxicology Program’s (NTP) Division of Toxicology Research and Testing. At NTP, he was instrumental in the design of the classic NTP bioassays; acute, subchronic and chronic, which are today c onsidered the “Gold Standard.” After leaving the NT P, Dr. McConnell continued to be involved in NTP

- type bioassays, and over his career he has been directly involved in more than 300 chronic bioassays and is still active in this regard today. He is a diplomate of the American College of Veterinary Patholog ists and the American Board of Toxicology, of which he is a past p resident. He has been a member of numerous national and international forums dealing with toxicology and pathology, including the National Academy of Sciences, Chair of the EPA Science Advis ory Panel, panel
member on the International Agency for Research on Cancer monographs and various panels of the World Health Organization. He is the author of more than 3 00 peer

- reviewed publications. His research has focused on the design and interpretati on of rodent bioassays of various toxicants, especially the pathology caused by various types of natural and man

- made fibers.

Dr. Stephen B

. Pruett is Professor of Immunotoxicology and Head of the Department of Basic Sciences at the College of Veterinary Medicine, Mississippi State University. He earned his B.S. degree from Northwestern State University of Louisiana (Microbiology) and his Ph.D. degre e from Louisiana State University School of Medicine in Shreveport (Immunology). He had post

doctoral training at the University of Alabama of Birmingham School of Medicine (Immunology) with Dr. J. Claude Bennett, and received training in toxicology and ph armacology during a Sabbatical with Dr. Albert E. Munson at the Medical College of Virginia. Dr. Pruett began his academic research career as an assistant professor in the Department of Biological Sciences at Mississippi State University and left at the ra nk of professor after 13 years to take a similar position at the LSU Health Sciences Center in Shreveport. He returned to Mississippi State University in his current position after 10 years at LSU. His research interests include theeffects of drugs, chem icals, and stress on the immune system. He has a long interest in

pesticides, drugs of abuse, and psychological stressors and has been funded by the National Institutes of Health (NIH) for work in each of these areas. He is currently a member of the Innat e Immunity and Inflammation Study Section for NIH and has served as a frequent ad hoc grant reviewer for several other NIH study sections beginning in 1990. He serves on the editorial boards of two leading toxicology journals, Toxicological Sciences and To xicology and Applied Pharmacology , and recently served several years as an Associate Editor for the Journal of Immunology . He has served in several leadership positions in the Society of Toxicology, including President of the South Central Chapter and Pres ident of the Immunotoxicology Specialty Section. He is a Fellow of the Academy of Toxicological Sciences and a member of the American College of Toxicologists. He has published more than 115 peer

- reviewed manuscripts and 10 book chapters, and has been an i nvited speaker at numerous meetings in the U.S., Australia, Europe, and Japan.

Dr. Pamela Williams is co

- founder of E Risk Sciences, LLP , a small, women

- owned business whose mission is to provide sound scientific analyses and tools to support risk

- based d ecision

making related to human health and the environment. She is also a Clinical Assistant Professor in the Department of Environmental and Occupational Health at the Colorado School of Public Health, and a Fellow with the non

- profit organization Toxico logy Excellence for Risk Assessment (TERA). Dr. Williams earned her B.A. from San Diego State University, San Diego, California (Sociology, Program in Applied Social Research); her M.S. from Harvard University, Boston, Massachusetts (Health and Social Beh avior); and her ScD from Harvard University, Boston, Massachusetts (Environmental Health and Health Policy & Management). From 2007 to 2009 she worked as a Senior Science and Science Policy Advisor in the Office of Research and Development at the U.S. Env ironmental Protection Agency. Prior that time, she worked as a Principal Health Scientist at ChemRisk (2003

– 2007), Senior Scientist at Exponent (1999

– 2003), Research Analyst at the Harvard Center for Risk Analysis (1996

– 1999), Scientist
at Environmental H ealth and Engineering (1997), Intern at the Agency for Toxic Substances and Disease Registry (1995), and Research Associate at Social Impact Assessment (1993

– 1994). Dr. Williams specializes in assessing human exposures and health risks in environmental,

c ommunity, and occupational settings. She has published over 100 papers, book chapters, and presentation abstracts on such topics. She has served as a technical peer reviewer for a number of journals and has peer

- reviewed screening

- level chemical assessme nts prepared by Health
Canada. She also served on the n

- Alkanes peer consultation panel under EPA’s Voluntary Children’s Chemical Evaluation Program. Dr. Williams currently serves as the Chair of the Risk
Assessment Committee at the American Industrial H ygiene Association, and formerly served on the Board of Directors at the Society for Risk Analysis (2003

- 2007). She was the 2007 recipient of the Joan M. Daisey Outstanding Young Scientist Award, granted by the International Society of Exposure Science in recognition of outstanding contribution to the science of human exposure analysis by a young scientist, and the 2009 recipient of the Chauncey Starr Distinguished Award, granted by the Society for Risk Analysis in recognition of excellent contributions to the field of Risk Analysis. She was named a Fellow of the Society for Risk Analysis in 2012.