UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

FEB 1:9 2013 

MEMORANDUM 

OFFICE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION 

SUBJECT: BEAD Chemical Profile for Registration Review: Methyl Isothiocyanate (MITC) 

(068103) 

FROM: 

THRU: 

Tara Chandgoyal, Plant Pathologist 

Biological Analysis Branch 

Jihad Alsadek, Economist 

Science Information and Analysis Branch 

Diann Sims, Chief 

Science Information and Analysis Branch 

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Timothy Kiely, Chief 

Economic Analysis Branch ~ v:1 \}'J\! 

Biological and Economic Analysis Division (7503P) 

TO: Jose Gayoso, Chemical Review Manager 

Risk Management and Implementation Branch 2 

Pesticide Re-evaluation Division (7508P) 

Product Review Panel date: January 30, 2012 

INTRODUCTION 

The purpose of this document is to convey usage information and a broad overview of the pest 

management roles of pesticides that are beginning to undergo registration review. The 

anticipated audience consists of the team of EPA staff currently evaluating the registration status 

of methyl isothiocyanate (MITC) and eventually the general public. This document builds upon 

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the data already provided in the "usage and label use data packages" that are also provided to 

Registration Review teams by BEAD. The document is based on information and data available 

to BEAD as of January 22,2013. 

COMMON FORMULATIONS AND APPLICATION METHODS 

Methyl isothiocyanate (MITC) is formulated as ready -to-use solution only and applied as a 

fungicide treatment for wood. 

USE SITES 

Agricultural Use Sites 

Methyl isothiocyanate (MITC) is not registered for agricultural use sites. 

Non-Agricultural Use Sites 

MITC is registered for use in large structural timbers (such as utility poles, pilling, and bridge 

timber). It is also applied to areas of timber where decay is suspected. 

USAGE 

Usage data are not available for MITC. 

BIOLOGICAL ASPECTS RELEVANT TO METHYL ISOTHIOCYANATE (MITC) 

MITC (ready-to-use solution) is only registered as a fungicide for wood treatment. MITC is 

generated when two soil fumigants (metam sodium and metam potassium) are applied to the 

soils. MITC is also the breakdown active ingredient of Dazomet when applied as soil fumigant. 

MITC produced by these fumigants has general biocide properties against fungi, nematodes and 

weeds. (http:/ /www.cdpr.ca.gov/docs/risk/rcd/mitc sb950.pd!). 

IDSTORY OF BEAD ASSESSMENT 

No BEAD assessments were found in BEAD's Official Records. 

SECTION 18 EMERGENCY REQUEST HISTORIES 

There have been no requests for emergency uses of this chemical on any crop or use site to 

contrel a pest under FIFRA Section 18 (http://cfpubl.epa.gov/oppref/section18/search.cfm). 

INFORMATION THAT MAY BE USEFUL FOR BEAD'S FUTURE WORK ON 

METHYL ISSOTHIOCY AN ATE (MITC) 

MITC is registered for non-agricultural use for wood treatment. No usage data are available. It 

would be helpful if data are available on the use rates of MITC for different types of wood, 

methods of applications, and efficacy in controlling wood decay fungi. 

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REFERENCES 

http://www .epa.gov /oppsrrd 1/reregistration/REDs/factsheets/ metamsodium~ fs.pdf 

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