Exhibit
      31.1








**Certification
      Pursuant to Section 13a-14 of the Securities Exchange Act of 1934 of**


**Thomas
      L. Wegman**


**(President,
      Principal Executive Officer and Principal Financial
      Officer)**







I,
      Thomas
      L. Wegman, certify that:




|1. | I
              have reviewed this Form 10-QSB for the quarterly period ended March
              31,
              2006(the
              “report”) of BioSpecifics Technologies Corp.
              (“registrant”);
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|2. | Based
              on my knowledge, the report does not contain any untrue statement of
              a
              material fact or omit to state a material fact necessary to make the
              statements made, in light of the circumstances under which such statements
              were made, not misleading with respect to the period covered by this
              report;
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|3. | Based
              on my knowledge, the financial statements, and other financial information
              included in this report, fairly present in all material respects the
              financial condition, results of operations and cash flows of the
              registrant as of, and for, the periods presented in this
              report;
|-- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------




|4. | The
              small business issuer’s other certifying officers and I are responsible
              for establishing and maintaining disclosure controls and procedures
              (as
              defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal
              control over financial reporting (as defined in Exchange Act Rules
              13a-15(f) and 15d-15(f)) for the small business issuer and
              have:
|-- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------




(a) Designed
      such disclosure controls and procedures, or caused such disclosure controls
      and
      procedures to be designed under our supervision, to ensure that material
      information relating to the registrant, including its consolidated subsidiaries,
      is made known to us by others within those entities, particularly during the
      period in which this report is being prepared;





(b) Designed
      such internal control over financial reporting, or caused such internal control
      over financial reporting to be designed under our supervision, to provide
      reasonable assurance regarding the reliability of financial reporting and the
      preparation of financial statements for external purposes in accordance with
      generally accepted accounting principles;




(c) Evaluated
      the effectiveness of the registrant’s disclosure controls and procedures and
      presented in this report our conclusions about the effectiveness of the
      disclosure controls and procedures, as of the end of the period covered by
      this
      report based on such evaluation; and




(d) Disclosed
      in this report any change in the registrant’s internal control over financial
      reporting that occurred during the registrant’s most recent fiscal quarter (the
      registrant’s fourth fiscal quarter in the case of an annual report) that has
      materially affected, or is reasonably likely to materially affect, the
      registrant’s internal control over financial reporting; and




5.
            The
                small business issuer’s other certifying officers and I have disclosed,
                based on our most recent evaluation of internal control over
                financial reporting, to the registrant’s auditors and to the audit
                committee of the registrant’s board of directors (or persons performing
                the equivalent functions):




(a) All
      significant deficiencies and material weaknesses in the design or operation
      of
      internal controls over financial reporting which are reasonably likely to
      adversely affect the registrant’s ability to record, process, summarize and
      report financial information; and









(b) Any
      fraud, whether or not material, that involves management or other employees
      who
      have a significant role in the registrant’s internal controls over financial
      reporting.






Date: May
      25,
      2007







/s/Thomas
      L. Wegman


Thomas
      L.
      Wegman


President


(Principal
      Executive Officer and Principal Financial Officer)





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