# EPA Registration 264
‐380 Vol.2

# Material to be added to an e-Jacket/Jacket Reg. No. Description: 

# DH'-1"1I.-.?''i
1. 0 

# Placementwithin the e-Jacket/jacket: p-Default: (chronological, top

# =newest)

o 

# File Location: (PDF page number, i.e., "before page 

# 45")

2. 0 

# Sendto Data Extraction contractors this material: o Newlystamped accepted label 

# y Notification o NewCSF o Other:

____________ _ 3. Attach this coversheetto the topofthe material orjacket. It mustbe well organized and clipped together, NOT STAPLED. Then givethe material with this coversheetto staffinthe Information Services Center (Room S-4900). 

# Reviewer's Narne:

# _--,D,-,,-

__**Q.L!.,,-,",,~,-,,:0>.L~.L~=-:"** _____ _ 

# Phone: _-=3_",-'.-':;'-_-=oC"-dJl-=-,-O

__

# Division: F BJP,

# D
Date:

__**~&==~~~~**

# __________________ __

CreatedAugust 19,2008

## PPIS DeficiencyNotice



## PMNUMBER: 

# 22-- REGISTRATIONNUMBER: 

# U'-/
Transferred from: SeneduAlemu (Macfadden) DateProcessed:

# _-,,25,-/f--I2-+1,-'1,-_
Thisjackethas been found to bedeficientaccording to established EPA data processing guidelines for the following reasons:
I.



## 3. 

## CUrrent accepted label 

## dated

__ I

__ I·

__ _

__is missing from thejacket.

__is missing acceptance stamp.

__Acceptance stamp is missing date and/or registration number.

_ Is missingthe followinginfonnation:

______________ _ 

## Acceptance letterdated

# l.JJlJ '\ and associated label are inconsistent concerning:

__Acceptance date. ')l-Productname.
_ Registration number.
Comments letter associated with label 

## dated

__ I

__ I

___is missing from thejacket.


## 4. Accepted (Basic 1

## Alternate) CSFdated

__1

__ 1

__ _

_ Is missing from thejacket.

__Is misfiled'orhas wrong registration number.

_ Sole active ingredient sourceproduct has been cancelled.


## 5.

_ Active and inert chemical percentages do not equal 100%. 

# o _ Other infonnationmissing

# /~within'thejacket. Seebelow for details. 

# Ple«,<..

# ~"'7 EPA .!llk'h"Q{"'" c{"Je,,L 

# S/II('"**R-~,t** Nme 0(\

# UNITED STATES ENVIRONMENTAL PROTECIION AGENCY WASHINGTON, DC 

# 20460

BayerCropScience Laura Phelps 2 T.W. AlexanderDrive 

### RTP, NC 27709 Subject: ETHRELbrand Ethephon Plant Growth Regulator Registration No,:**264~257** 

### Date Submitted: 3/14/11 DecisionNo.: 447178
PREP brand Ethcphon Plant Regulatorfor Cotton RegistrationNo.: 264-380 Date Submitted: 

## 3/14111 DecisionNo.: 447179
PREP brand EthephonforCotton and Tobacco Registration No.: 264-418 

### Date Submitted: 

## 3114/11 DecisionNo.: 447180
CERONEbrand Ethephon Plant Regulator Registration No.: 264-377 Date Submitted: 3/14/11 DecisionNo.: 447181
Dear Ms. Phelps: OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION



# MAY 1 12011

The

## Agencyis inreceiptofyourApplications for 

## Pestictde Notification underPesticide Registration Notice (PRN) 98-10. The**R~gistration** 

### Division (RD) ,has conducted a reviewofthisrequestfor 

## its applicabilityunder PRN 98-10 and finds thatthe actionsrequested fall within the scope ofPRN 98- 

## 10.
TheAgencyacknowledges the removal ofthe patentnumberfrom the label.
The label submittedwiththe applicationhas been stamped "Notification" and will beplaced in our records. Ifyou have questions concerningthis letter, please contactDominic Schuler at 703-347-0260 or viaemail atschuler.dominic@epa.gov. Sincerely,

# ~"VVVA Tony Kish ProductMana er22 FungicideBranch RegistrationDivision (7504P)**Pf.'~"** 

### "'edb 

### t ot':titJ". 

### on'" • b fo,. 

### m ; 

# S}?'il'133 PdntForm

### Jl.gJ"'~~i!!!o.________

### ....!Fo:2!l~lW'~P~'~"~v~.~'~. 

# (**JN~o",.jg 2027110-00;!l!~'~0t.,.':::=;;;;;;;;;;=;;;;;:!......,**  

# &EPA

1. 

### Company/Product NUmber 

### 264-380 United Stateo 

## Environmental Protection Agency Washington, DC 20460

# ~ Registration Amendment x Other OPP Identifier Number



## Application for Pesticide**~** 

## Section I 2. 

### EPA Product Menager Mr. TonyKish 3. 

### Propoeed Cle

.. ification 

# o Non. 

# 0 Re.tricted 4. 

### CompenylProduct (Name)

PREP brand Ethephon PlantRegulatorforCotton 

### PM' 22 5. 

### Name and Addre•• of Appficent (Include ZIP C1dll/



### BayerCropScience LP P. 

### O. Box 

### 12014; 2T. 

### W. AlexanderDr. Research Trianqle Park, NC 

### 27709 

### 6. Expedited Review. In accordance with 

### FIFRA Section 3(cH3! (blli!, my product is similar or Identical in composition and labeling to: 

## o EPA 

## Reg. No.

______________ _ 

# o Chllck ifthis is II nllw "ddf(J$$ 

### Product 

### Name 

# o o o Section**~** 

## II
Amendment

- Explain below. Resubmlsaion In r88pon" to 

### Agency lettardeted

______ _ Notification

- Explain below. 

# o 

# o o
Explanation: 

### u
.. eddltlonal pogal.llf naceSlary. IFor section I 

### and Section II.) Anal 

### printed labela in raspon.e to 

### Agency lener dated**~Me Too~**  

### Appllcetion. Othar

- EXplain below.

BayerCropScience is submitting a notificationfor PREP brand Ethephon plantRegulatorfor Cotton to remove the patentnumberfrom thelabel.


## Section

- III 1. 

### Meterial Thill 

### Product Will Be 

### Packaged In: 

### Child·Rosistent packoging Unit Packaging Wetar Solubla Packaging 

# B V

..- 

### No 

# B V

.. No 

# E3 V" 

### No

e 

### CsrtifTclltion must btl submifttHJ If**~Y**..**~** 

### No. per If**·Yos~** 

### , Package wgt Unit Packeging wgt. container

3. 

### Locotion of Net Content. Infonnstion 

# o Labal 

# o Containar 6. 

### Mannar in Which Labal ie Affixed 

### to Product 4. 

### Sito/s) Retoll Containar

Uthograph Paper aluad Steneifed I



## Section

- IV No. per containor 

### 2. Type of Conainer

# ~::=o Gle

.. Paper Othor

### (Spslif:~'~,:. :'

_____ _ 5. 

### Locotlon of Label Diractlan. ' '"



# E3 On Lobel " 'c 

### On**Labtlr.III~~2ompenVing'product**

1. 

### Contact Point (Complete items directly bfllow for identificstion ofindividual 

### ro ba contacted, if

### naC6ssary, ro

### p':o'C~ thi$ .pp.licariop./**,,~~~~~** 

### Title Reg. Affairs Specialist Telaphona Na'. /lncluda Arso Cade) N_ 

### Laura Phelps 

### Certification I 

### certify thet the statements I have made on this form and all attachments th8lato are true, accurate and complete. I 

### ecknowledge that enyknowingly 101

.. 

### or misleeding lltetement mey bapuniehable by fine or imprisonmant or both under applicable lew. 8. 

### Oate Applicotion Receivad 

### (Stamped)

4. TYPed 

### Name Laura Phelps

EPA 

### Form 8570-1 

### /R.v. 8-941 

### PreVIous editions are obsolata. 3. Title RegulatoryAffairs Specialist

March 

### 14,2011

Whtte • EPA FUll 

### Copy /origlnal) Vellow •Appllc.nt Copy

# BayerCropScience

March 10,2011

Document Processing Desk (NOTIF) Registration Division (7505P) Office ofPesticide Programs U.S. Environmental ProtectionAgency OnePotomac Yard (South Building) 2777 S. Crystal Drive Arlington, VA 22202

Mr. Tony Kish, RD Team 22 (



## Subject: PREPbrand EthephonPlantRegulatorfor Cotton,No. 264- 380; Removal ofPatentNumber
DearMr. Kish:

BayerCropScience is submitting a notification for PREP brand Ethephon Plant Regulatorfor Cottonto remove the patent number from the label.
This notification is consistent with the provisions of"PRNotice 98 w 

## IO. No other"changeshavebeenmadeto-the labeling or theConfidential Statement of Formulaforthis product. I understandthat it is a violationof 18 U.S.c. 

# 8

...**~** 

# A

..

.. E



# c-R

Bayer CropScience P. O. Box 12014 2. T. W. Alexander Drive Research Tr'langle Park, NC 27709



### ,,-, 

## , • 

# . 

# . _ C ,< 

## Section 1001 to willfully make any false statement to 

## EPA. I further : (' '" understandthat ifthe amended label is notconsistent with the requirements of ( 40 CFR §§ 156.10, 156.140, 156.144, 156.146 and 156.156,this product may" • ::. beinviolation ofFIFRA and I maybe subjected to enforcement action and eeL <- '- 

# • 

# . , 

# . penalties underSection 12 and 14 ofFIFRA". "**~** 

## "
Enclosed are an EPAForm 8570-1 and one copy ofthe revised PREPbrand Ethephon Plant Regulator for Cottonlabel for review.

Please contact me ifyou shouldhave further questions. Sincerely, 

## •

, 

## " " 

# ,

# ( 

# BayerCropScience

Laura Phelps Regulatory Affairs, Herbicides & 

### PGRs Bayer CropScience 

### 2 T. W. Alexander Drive 

### RTP, NC 27709 office: 919-549-2302 

### mobil:919-352-8075 email: laura.phelps@bayer.com 

## (



## , " '" 

## , , , , ,c 'c

( 

### , ( 

## ,

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## " , , 

## "

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### , 

## ,

## PREPTM 

# brandEthephon PLANTREGULATORFORCOTTON FORCOMMERCIALUSE ORAGRICULTURAL USE ONLY. NOTFORRESIDENTIAL USE. ACTIVE INGREDIENT: 

# NOTIFICATION MAY i 

# 1iOl1

Ethephon (2-chloroethyl) phosphonic acid*

....·····........................······.·.. n •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

### 39.9% 

### INERTINGREDIENTS:

........................................................................................................................................................ 60.1 % 

### *This productcontains 4 pounds ethephon per galion. 

## EPAReg. No. 264-380 EPAEst. No. 264-PA-Ol 

# KEEP OUT OF REACHOF CHILDREN 

# DANGER PELIGRO

Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. (If you 

### do not understand the label, find someone to explain it toyou in detail.) For MEDICAL And TRANSPORTATION Emergencies ONLY Call24 Hours A Day IM800M 334-7S77 For PRODUcr USE Information Call IM866M99BAYER (l-866M992-2937) 

# FIRSTAID IF IN EYES: 

# • Hold eye open and rinse slowly and gently with water tor 15-20 minutes. 

## • Remove contact lenses, if present, afterthe first 5 minutes, then continue rinsing eye. 

## • Call a poison control center or doctorfor treatment advice. IF ON SKlNOR 

## • Take olf contaminated clothing. CLOTHING: 

## • Rinse skin immediately with plenty of water for 15-20 minutes. 

## • Call a poison control center or doctorfor treatment advice. IFSWALLOWED: 

## • Immediately call a poison control center or doctor for treatment advice. 

## • Do not induce vomiting unless told to do so 

### by a poison control center or doctor. 

# • Have person·sip a glass ofwater if able to·swallow. 

# • Do not Qive anythina by mouth to an unconscious person. For MEDICAL Emergencies Call24-Jlours A Day IM800-334-7S77. Have the nroduct container ortabet withvou when callin a Doison control center ordoctoror .:::oin6 f"rtreat'!!!!!!:. NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the possibility thrJ**cv~~cxposu~e** to materials otherthan this product may have occurred. No specific antidote is available. Probable mucosal damage**m"l~'** contraindb::tts the use of gastric lavage. 

# PRECAUTIONARYSTATEMENTS DANGER HAZARDSTO HUMANSAND DOMESTICANIMALS Corrosive. Causes irreversible 

### eye damage and skin irritation. Harmful ifswallowed or absorbed through skin. Do not get in eyes, on skin, or on clothing. Harmful orfatal if swallowed. Avoid contamination offood.

## PERSONALPROTECTIVE EQUIPMENT (PPE) Applicators and other handlers must wear long-sleeved shirt and long pants, chemical resistant gloves made of anywaterproof material (such as Nitrile, Butyl, Neoprene and/or Barrier 

### laminate), shoes plus socks and protective eyewear. When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFA 170.240 (d) (4-6)]. the handler PPE requirements may be reduced or mooified as specified in the WPS. 

### Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this producfs concentrate. Do not reuse them. Follow manufacturer's instructions for cleaningfmaintaining PPE. If no such instructions for washables, use detergent and hotwater. Keep and wash PPE separately from other laundry.
User

## SafetyRecommendations Usersshould wash hands before eating, drinking, chewing gum, using tobacco or using the toilet Users should remove clothing immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. Users should remove PPE immediately after handling this product As soon as possible, wash thoroughly and change into clean clothing. Wash the outside ai-doves before removina. 

## ENVIRONMENTAL HAZARD Avoid spray driftto nearby crops as this product may cause temporary modifications in plant growth. Do notcontaminate water used for irrigation or domestic purposes. Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not contaminate water when disposing of equIpment washwaters. Do not exceed the rate of PREpTM brand Ethephon Plant Regulator for Cotton per acre peryear recommended on this label. 

## SPRAYDRIFT Avoid spray drift. Do notapply when weather conditions maycause drift. Do notallow this productto drift on to**non~target** areas. Drift may result in illegal residues or injury to adjacent crops and vegetation, in the form of leaf yellowing and defoliation. To avoid spray drift, DO NOTapply aerially when wind speed is greaterthan 

### to mph or during periods oftemperature inversions. Use of larger droplet size will also reduce spray drift. AVOIDING SPRAY DRIFT ATTHE APPLICATION SITE IS THE RESPONSIBILITY OFTHE APPLICATOR. The interaction of many**equipment~and~weather"related** factors determine the potential for spray drift. The applicator is responsible for considering all these factors when making decisions. The following drift management reqUirements must be followed to avoid**off~target** movementfrom aerial applications to agricultural field crops. These requirements do notapplyto forestry applications, public health uses orto applications using dry formulations. 1. The dlstance ofthe outer most nozzles on the boom must not exceed 3{4 the length ofthe wingspan or rotor. 2. Nozzles must always point backward parallel with the air stream andnever be pointed downwards more than 45**O(>~TAPS.** Where states have more stringent regulations" theyshould be observed. The applicator should befamiliar with and take into accountthe information covered in the Aerial Drift Reduction Advisory below: 

## AERIAL DRIFTREDUCTION ADVISORY [This section is adviSOry In nature and does notsupersede the mandatory label requirements]. 

### INFORMATION ON DROPLET SIZE The most effective way to reduce drift potential is to apply large droplets. The best drift management**~*"'t-<;!gy** is to aprly the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but wlll (lot pn'!vent drift 

### if applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature a!,ti humidity, and Temperature Inversions). 

### CONTROLLING DROPLETSIZE Volume

- Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure**~** Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger droplets. When higherflow rates are needed, use higherflow rate nozzles instead of increasing pressure. Number of nozzles**~** Use the minimum numberof nozzles that provide uniform coverage. Nozzle Orientation**~** Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other orientations and is the recommended practice. SIgnificant deflection from horizontal will reduce droplet size and increase drift potential.

2

### Nozzle Type**~** 

### Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce larger droplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight 'back produce the largest droplets and the lowest drift. 

### BOOMLENGTH For some use patterns, reducing the effective boom length to less than 3/4 of the wingspan or rotor length may further reduce drift without reducing swath width. 

### APPLICATION HEIGHT Applications should not be made at a height greater than 10feet above the top of the target plants unless a greater height is required for aircraft safety. Making applications atthe lowest height that is safe reduces exposure of droplets to evaporation and wind. 

### SWATHADJUSTMENT When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adiustment distance should increase, with increasing drift potential (higher wind, smaller drops, etc.). 

### WIND Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type determine drift potential at any given speed.**App~cation** 

### should be avo'lded below 2 mph due to variable wind direction and high inversion potential. NOTE: local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and how they affect spray drift. 

### TEMPERATUREAND HUMIDITY When making applications in low relative humidity, set up equipment to produce larger droplets to compensatefor evaporation. Droplet evaporation is most severe when conditions are both hot and dry. 

### TEMPERATURE INVERSIONS Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the movement of 

### smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly diSSipates indicates good vertical air mixing. 

### SENSITIVEAREAS The pesticide should only be applied when the potential for drift to adjaCent sensitive areas (e.g. residential areas, bodies of water, known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive areas). 

# DIRECTIONS,FORUSE It is a violation of Federal lawto usethis product in a manner inconsistentwith 

### its labeling. Do notappfy thIs product in a waythatwill contactworkers orother persons, either directlyorthrough drift. OnlY;lrotected

handlers may be in thearea during application. Forany requirements specificto your State orTribe, consult**tn~** 

### agency responsiblefor pesticide regulations. Read entire label before usIngthis product. 

## ,---------cc----c:=c-----,c--------- -- ------, 

## AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR p::.r; ;70. This s(anda(d contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouso:;, cr,d handlers 

### vf agricultural pesticides. It contains requirements for training, decontaminal'lon, notification, and emergency assistance. It alsc cont.lins specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE),**noti~ication** 

### to workers and restricted-entry interval. The reqUirements in this box only apply to uses of 

### this product that are covered by the 'Norkor Protection Standard. Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches per year. PPE required for early entry to treated areas that 1s permitted under the Worker Protection Standard and that involves contact with anything that has been treated such as plants, soil or water is coveralls over**long~sleeved** 

### shirt and long pants, chemical resistant gloves made of any waterproof material, such as nitrile, butyl, neoprene, or barrier laminate, chemical resistant footwear plus socks, and protective eyewear. For overhead exposure,**chemical~resistant** 

### headgear is also required. Notify workers of the application by waming them orally and posting warning Signs at entrances to treated areas.

3

## STORAGEAND DISPOSAL Do not contaminate water, food, orfeed by storage or disposal. 

### PESTICIDE STORAGE Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, follow all precautions indicated above and clean up immediately. Before cleaning up, pul on full length trousers, long sleeved shirt, protective gloves, and goggles or face shield. &:Iak up spill with absorbent media such as sand, earth or other suitable material and 

### dispose ofwaste a1 

### an approved waste disposal facUity. PESTICIDEDISPOSAL Pesticide wastes are acutely hazardous. Improper disposal of exceSs pesticide, spray mixture, or rinsate is a violatIon of Federal law. 

### If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency orthe HazardousWaste representative at the nearest EPA Regional Office for guidance. CONTAINER DISPOSAL Triple rinse (or equivalent) the empty containers. Then offer for recycling or reconditioning, or puncture and dispose of in a sanitary landfill, or

### by incineration or ifallowed by state and local authorities, by burning. If container is burned, stay out 

### of smoke. RETURNABLE

- REFILLABLE CQNTAINERS After use, return the container to the point of purchase or designated locations. This container must only be refilled with PREpTM brand Ethephon for Cotton and Tobacco. DO NOT REUSE THE CONTAINER FOR ANY OTHER PURPOSE. Prior to refilling, inspect thoroughly for damage such as cracks, punctures, abrasions and damaged or worn out threads on closure devices. Do not refill or transport damaged or leaking containers. Checkfor leaks after refilling and before transportation. If the container is not being retifled, return it to the paint of purchase. 

### GENERAL INFORMATION A toliar spray of PREpTM brand Ethephon Plant Regulator for Cotton will accelerate opening of mature unopened cotton bolls and enhance defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon Plant Regulator for,Colton treatment allows increased efficiency from a once-over harvest. Some premature drop at small, immature bolls may be associated with treatment. Do not apply before sufficient, mature, unopened bolls have developed to produce the desired yield of colton. A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to be sliced with a sharp knife, and when the seed coat becomes light brown in color. For best results, thorough and uniform spray coverage is required. 

### It is essential that the bolls are contacted by the spray to obtain optimum boll opening. Observe treated fields closely. Harvest at**o~imum** boll opening and defoliation, generally 14to 2t days after treatment. Sustained cold weather with average day and night temperatures of 65"F or lower after treatment with PREpTM brand Ethephon Plant Regulator for Cotton will delaythe boll opening response. DO NOT APPLY PREpTM BRAND ETHEPHON PLANT REGULATOR FOR COTTON IF RAIN IS EXPECTED WITHIN 6 HOURS. Rainfall wiJhin·6 hours of application may reduce product performance. ';' Certified cotton seed growers should observe boll and seed maturity beJore treatment with PREpTM brand Ethephon Plant Regulator for Cotton. Bolls not completely mature might open with treatment of PREpTM brand Ethephon Plant Regulator for C.?1t0,1 £,iving lower quality seed. IMPORTANT: Do not apply PREpTM brand Ethephon Plant Regulatorfor Coltonthrough anytype of irr;gatiun .;;ystem. SPRAY PREPARATION Add 

### 1/2 to 

### 3/4 ofthe required amount ofwaterto the spray tank. Start agitation. Add the required amount of PREpn brdntl Ethephon Plant Regulator for Colton, and the remaining amount of water. Prepare only as much spray solution a3 

### co.;, be used on the day of mixing. Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment, or any airplane parts. ANY SPILLS SHOULD BE RINSEG ,r.IIJlcDIATEl Y WITH PLENTY OFWATER. Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipmem or any airplane 

### parts. EQUlPJ\.1ENT**CLEAl~ING** Spray deposits of PREprM brand Ethephon Plant Regulator for Cotton, when left on aircraft acrylic plastic type windshields for longer than 1 hour, may react with this material, forming an opaque film or spots on the surface which cannot be removed by washing with water orany other cleaner. Rinse windshields with water immediately after each tankload of PREpTM brand Ethephon Plant Regulator for Cotton has been appned. Thoroughly rinse the aircraft with clean water aftereach day PREpTM brand Ethephon Plant Regulator for Colton is applied.

4PREpTM brand Ethephon Plant Regulator for Cotton may also affect certain paints, and 

### if accidental deposits on painted objects such as cars, trucks, agricultural equipment, etc. occurs, these objects should be rinsed with water as soon as possible (within 1 hour) to prevent permanent staining of the painted suriace. Because of the acidic nature of this product, prolonged exposure to spray deposit wirr damage acrylic plastics, certain paints, and metals. Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted suriaces wjthjn an hour after exposure to spray deposits. At the end of each day, rinse thoroughly with a detergent and water all the metal parts ofthe aircraft and the associated spray equipment exposed to the spray deposits.


### BOLL OPENING

CONDITIONS EXPECTED 5-7 DAYS AFTER

TREATMENT
Hot and dry 80'For higher Dry with temperature 7S"Fto 80'F Cool but higher than 65'F Rank collon 

### Rates ForBoll Opening

PREPTM brand Ethephon ONE GALLON OF Plant Regulator for Collon PREpTM brand Ethephon Plant Regulator for Cotton QUARTS/ACRE TREATS

1.0 (1.0 Ib a.i.) 4 Acres t.S (1.5 Ib a.i.) 2.5 Acres
2.0 (2.0 Ib a.i.) 2 Acres 2.0 (2.0 Ib a.i.) 2 Acres SPRAY VOLUME GALJACRE GROUND AIR

t5 to 50 15toSO
1St050 25toSO 2to 5" 2 to**5~** 2 to 5* 

### 5 "NOTE: For California andArizona use a volume of no less than 5 gallons per acre for aerial applications


### Time ofApplication (Boll Opening) Apply when there are sufficient mature unopened bons to produce the desired yield, but no later than when 60% of the bolls are opened (see General Information section on how to test for boll maturity). 00 not tank mix PREpTM brand Ethephon Plant Regulator for Cotton with a desiccant if the cotlon isto be spindle harvested.

5

## PRECONDITIONINGFORDEFOLIATION

Rates ForPreconditioningForDefoliation

CONDITIONS EXPECTED 5-7 DAYS AFTER

TREATMENT
Hoi and dry 80'F or higher Cool but higherlhan 65'and also for rank colton PREpTM brand Elhephon Plant Regulator for Cotton QUARTS/ACRE
0.5 (0.5 Ib a.i.) 

### 1.0 (I.O Ib a.i.) ONE GALLON OF PREpTM brand Elhephon Plant Regulator for Cotton 

## TREATS
8 Acres 4 Acres SPRAYVOLUME**~AI** 

### [ACRE 

### GROUND AIR

151050 2 

### to 5* 151050 2105*
*NOTE: For California andArizona use a volume of no less than 5 gallons per acre for aerial applications.


### TimeofApplieation**(pr~onditioning)** Apply PREpTM brand Elhephon Plant Regulator for Cotton 4 to 7 days priorto application of defoliant or lank mixed with the defoliant (see section on Compatibility). Do nollank mix PREpTM brand Ethephon Plant Regulatorfor Cotton with desiccants unless plant desiccation is required.**Pr~treatment** 

### With Defoliants Prior to PREpTM brand Ethephon Plant Regulator for CoHon Treatment lithe cotton is overly rank or laying down in the middles and good spray coverage 

### 01 the bolls with PREpTM brand Ethephon Plant Regulator lor Cotton is difficult, a pretreatment with defoliants will be useful to improve boll coverage with PREpTM brand Ethephon Plant Regulator for Cotton. Use dosage rates of PREpTM brand Ethephon Plant Regulator for Collon recommended for boll opening. Read and observe all appropriate label usedirecnons and precautions for the defoliant used. Do not use a defoliant before there are sufficient mature unopened bolls to produce the desired yield (see General Information section on howto test for Boll Maturity). COMPATIBILITY PREpTM brand Ethephon Plant Regulator for Cotton is compatible with DEF, FOLEX, DROPP, HARVADE, METHYL PARATHION, GUTHION AND MALATHION, and may be applied in sequence or as a tank mixture (DO NOT TANK MIX WITH DEFOLIANTS OR DESICCANTS IN CALIFORNIA AND ARIZONA). In some cases slight reduction in boll opening response has been observed when tank mixes with deloliants were used. Good agitation in the spray tank is essential and a tank mixture should- not be allowed to stand without agitation for more than 

### 5 

### to 10 minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. PRECAUTION: NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpiM BRAND ETHEPHON PLANT REGULATOn FOR CanON WITH DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLDRC·JS ACIDS WHICH ON HEATING WILL EMITTOXIC CHLORIDE FUMES. DO NOT MIX PREpTM BRAND ETHEPHON PLANT REGULATOR FOR COnON WITH AMMONIUlIr; Tn'O.:;ULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OFTOXIC FUMES.


### WHENTO HARVEST: Do not harvest cotton sooner than 

### 7 days after a treatment with PREpTM brand Ethephon Plant Regu!<"tor 'or Callan. Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might retJuce the full advantage of the treatment and too late a harvest may result in reduced quality and loss of lint which will dropfrom the plant. USE LIMITATIONS Do not exceed a maximum at 2.0 lb. ethephon active ingredient per acre per year through combined or repe3.ted uses of any ethephon products. Boll Opening: Do not tank mix PREpTM brand Ethephon Plant Regulator for Cotton with a desiccant if the cotton is to be spindle harvested. Pre-Condition for Defoliation: Do not tank mix PREpTM brand Ethephon Plant Regulator for Cotton with desiccants unleSS plant desiccation is required. Do not use a defoliant before there is suflicient mature unopened bolls to produce the desired yield {see General Information section on howto test forboll maturity. Do not plant another crop within 30 daysaftertreatment.

6

### USEPRECAUTIONS Avoid spray drift to nearby crops as this product wj)) cause modifications in plant growth. Plant injury or reduced yields wiD result Mix only the amount of spray you expect to use each day. Do not allow mixed solution to stand overnight.



## IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If tenns are not acceptable, return the unopened product container at once. By using this product, useror buyer accepts the following Conditions, Disclaimerof Warranties and Limitations of Liability. COND1TIONS: The directions for use of this product are believed to be adequate and should be followed carefully. However, it is impossible to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness orother unintended consequences may result because of such factors as weather conditions, presence of other materials, or the manner of use orapplication, all of

### which are beyond the control of Bayer CropScience. All such risks shall be assumed bythe user or buyer. DfSCLAIMER OF WARRANTfES: BAYER CROPSCIENCE MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to make anywarranties beyond those contained herein or to modify the warranties contained herein. BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OFTHIS PRODUCT. lIMITATfONS OF UABILlTY: THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE'S ELECTION, THE REPLACEMENT OF PRODUCT.



# (.ty Bayer CropScience
BayerCropScience LP P.O. Box 12014,2T.W. Alexander Drive Research Triangle Park,North Carolina 27709 1-866-99BAYER (1-866-992-2937) PREpTM brand Ethephon Plant Regulatorfor Cotton (MASTER) Approved 11/27/02, 

### Notification 03/14/2011

7

# MATERIAL TO BE ADDED TO JACKET

REG 

# # Description:

check all that apply



# 0 new stamped accepted label**~** ::ii, Q" 

# 0 new CSF 

# .... 0 

# Wnotification**~.** C")



# Instructions: Attach this sheet to the top ofALL material sent to the file room (both loose paper and new material in jackets). This sheet will be imaged; a clear description will aid in finding material in the e-jacket Remove staples from all material. Ifreturning loose paper then hold togetherwith a binder or paper clip. CSFs should be placed in the CSF folder (if returning jacket) or covered with a red CBI sheet (if returning loose paper). Material to be returned to file room should be place in the appropriate bin. 

# R'''=fllplZlt

# ~ D", 

# :?

# = -/6

Phone: 

# .3(2.S-- 

# U49' s a Division:

....

# J.tJt

.....___......

### UNITED STATES ENVIRONMENTAL PROTECTIONAGENCY WASHINGTON, D.C. 20460

OFFICE Of PREVEC'iTION, PESTICIDES Al'iD TOXICSUBSTANCES 

# AUG 1 9 2010

Ms Laura Phelps Bayer CropScience LP Po Box 12014,2 T.W. Alexander Drive, Research Triangle Park, NC 27709
SUBJECT: LabelNotification(s) for Pesticide Registration Notice PRN 2007-4 Request Storage and disposal changes EPA Reg. No. 264-380 Application Dated July 30, 2010
Dear Registrant:
The Agency is in receipt ofyourApplication for PesticideNotificationunder Pesticide RegistrationNotice (PRN) 2007-4 dated 

## 7/30/2010 for theproduct PREP"{ 

## Brand Ethephon PlantRegulator

## for Cotton. The RegistrationDivision (RD) has conducted a review oftrusrequest for its applicability under PRN 2007-4 and finds thatthe action(s) requested does not clearly fall withint,he scope ofPRN2007-4 and will require additional administrative review ofthe related files. A summary ofourfindings include:
The languageused in the storage and disposal section goes beyond the scope ofPRN .2007-4 and this mustbe reviewed as an amendinent.

. Therefore, the RD has determined thatthis actionis denied and will be further processed 

# as an amendment and our records have beenupdated accordingly. The label submitted withthe application is considered proposed drafts and has been forwarded to Tony Kish (PM 22) for further processing.
Ifyou have any questions, please contactme directly at 703-305-5335 or Banza Djapao ofmy staffat703-305-7269. Sincerely,

# rldJ{~~ Paul Mastradone, Acting Leader**~** 

## Notifications & 

## Minor FOlTImlations'feam Leader Registration Division (7505P) Office ofPesticide Programs

# ayer CropScience

July30, 2010
DocumentProcessingDesk (AMEND) Office o[PesticideProgram (H7504P) 

# u.s. EPA, Room S4900 One Potomac Yard Arlington, VA 22202 -4525

ATTN: 

## Mr. Tony Kish (PM 22) RegistrationDivision (7505P) (



# 8 .**~\** 

# \, 

# 8AYER

SubjectPREpTM brand Ethephon PLANT REGULATORFORCOTTON (Reg. No.: 

## 264- 380): Submission ofthe Application ofPesticideNotificationunderPRNotice 2007-4 (Ref.: the Pesticide Container and Containment Final Rule, August 16, 2006)
DearMr. Kish: Bayer CropScience herein submits this amendmentfor the PREPTM brand Ethephon PLANT REGULATORFORCOTTON (Reg. Nil.: 264- 380), a solution containing ethephon as the active ingredient. The amendmen-tis tocomplywiththe label language required bythe regulation in40 CFRpart 156 established bythe Final Rule "Pesticide Management and Disposal; Standards for Pesticide Containerand Containment" (August 16,2006).Based on the Gnidance issued underthePRNotice 2007-4 andthe productspecific infonnation, we propose the following "ContainerDisposal" labeling (see Secpoqq for "Storage and Disposal"): '

__ , , ,
CONTAINER DISPOSAL Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal 

### to or lessthan 5 gallons) Non-refillable container. Do not reuse or refill this container. Offerfor recycling, if available. Triple rinse or pressure rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds afterthe flow begins to drip. Fill the container 1f4full with water an'f-'**~** , _ recap. Shakefor 10 seconds. Pour rinsate into application equipment or a mix tank orstore rinsate for later use or**disjS6~al.** ' Drain for to seconds afterthe flow beginsto drip. Repeatthis procedure two more times. Once container is rinsed, offerfor recycling ifavailable or puncture and dispose of in a sanitary landfill. '" 'PIe••• ,... 

### ".."r.wne "'ore**~"**

### ..to F rm**~twrov.d._** JB 

### No. 2070-0080 

# ( Print Form
UnitltCl Stllto. 

# §Registration OPP Idontifier Number 

# &EPA Environmental Protection Agency x Amendment W

.. 

### hington, DC 20460 

## Other

Application for Pesticide

- Section I
1. 

### ComponylProduct Number 2. EPA 

### Product Managor 3. 

### Propo•• d Cla.sificetion 264-380 

### Mr. Tony Kish 

# o None 

# o Restrict6d 4. 

### CompanylPtoduct (Nama) PM'



### PREP"'"' brand Ethephon PLANT REGULATOR FOR COTTON 

### 22 5. 

### Name and Addra

..of Appllc.nt (Include ZiP CodflJ 

### 6. Expedited Review. In accordance 

### with FIFRA Section 

### 31cH31

BayerCropScience LP Ibllil. my product Is similar or identical in compositionand labeling P. 

### O. Box 12014; 2

### T. W. AlexanderDr. 

### to, ResearchTrianqle Park, NC 27709 

### II EPA Reg. No. 

# D Chtlck ifthi$ i$. ntlw .ddfe&S 

### Product 

### Name 

## Section

- II 

# 0 Am.ndm.nt· EXplain below. 

# D Final 

### printed label. in r.'Pone.to Ag'ncyI.tter d.t.d 

# D Re,ubml.eiion In r•• pon•• to Aglncy lenerd.ted 

# D -Mo

### Too· AppflC.tion.

## NOTIFICATlo!~ 

# D Notification· Elq:Jloin b.low. 

# D Oth.r· Elq:Jlain b.low. 

## A!lr. 1 9 ?P'" Explanation: 

### u•• additional page(s) if n.c••••

### ry. (For .Ictlon I .nd Section II.)
8ayerCropScience would like to add the required containerdisposal languagetothe PREP""' brand Ethephon PLANTREGULATOR 

### FDR conaN (Reg. No.: 264- 380) label perPR notice 2007-4.


## Section

- III
1. Moterial

## nu. Product WiD Be 

### Pockaged In: 

### Child-R.aistant Packaging Unit Packaging Wat.r Soluble Peckaging 2. Typ. 

### ofContainer

# ~r'- 

# @V" @ 

# V

..**§~t.** X N. X N. N. 

### X Plastic Gla

.. a 

### CertJlication mU3t If -V.s- No. per If -V.,· :- No. por P.p.r Unit 

### P.ck'ging wgt. container Package w_gt conteiner Other (Specify) 

### btl $ubmitttH:I I 3. 

### Locetion of Net Contents Information 4. 

### Size(s} Rotall Contain.r 5. 

### Locetion of label 

### Oir.ction.



# I8J 

# o Com-iner 2.5g or larger

### ~ OnLllboi lab_ 

### On UbelinG eccomp.nyingproduct 6. 

### Manner in Which Labol i, 

### Affix.d to 

### Produot 

# K: Uthogreph 

# U Other Paper**~Uitd** 

### Stenci Od 

## --.="' Section

- IV , , <C c 1. 

### Contact Point (CtJmpl". itlHTl$ dirtICt/y btJ/owfOfidflntificstion 

### ofindividIJs/

### to ba contsct.d, ifn.ceu.'Y, 

### to ptOCNS this**.,,~diwf,fiot1.J** 

### " 

### , N_ 

### Title TlJlephona No. (I[IOIOOe**Ar~., ct~.,**  

### Laura Phelps Reg. Affairs Specialist 919-549-2302 c 

### Certification '. c , { , 8. 

### Ost. Applic.tJon, Ic.rtifythat the ,tatements Iheve mad. on thic form and all 

### attet:hmonts thO/ato 8ro tl\l•• accurate and complsto. e**ke~~l;'ed** 

### " 

## , ," 

### , Iecknowl.dg. that any knowingly fal

.. er misleading .tatement mev b. punishable by fin. or imprisonment or ,(Stampe,d,l: , both under applicablalaw.
c

# 2d~~

# 1P NJjJS 3. 

### Title co "- 

## " c 

### RegulatoryAffairs Specialist -" 

### ,
c 

### " '. 4. Typitd 

### Nama 

### 5. Oat. Laura Phelps July30,2010**~ ~** EPA 

### Form 8570-1 (Rov. 8-S41 

### Prelllous odltlon, .ro obsolete. Whtta • 

### EPA FlIto 

### Copy (orIglnall VeVow •AppllcSllt copy

## (

Rigid Non-refillable containers that are too large to shake (i.e., with capacities greaterthan 5 gallons or 50 Ibs) Non-refillable Containers Non-refillable containers

- Do not reuse or refill this container. Referto Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs infonTIation as follows.
Bottom Discharge IBC (e.g.

- Schuetz Caged IBC orSnyderSquare Stackable) Pressure rinsing the container before final disposal is the responsibility ofthe person disposing ofthe container. To pressure rinse the containerbefore final disposal, emptythe remaining contents from the IBC into application equipment or mixtank. Raise the bottom ofthe IBC by 1.5 inches on the side which is opposite ofthe bottom discharge valve to promote more complete product removal. Completely remove the top lid ofthe IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. Top Discharge IBC, Drums, Kegs (e.g.- Snyder t20 Next Gen, Bonar Bt20, Drums, Kegs). Triple rinsing the container beforefinal disposal is the responsibility ofthe person disposing ofthe container. To triple rinse the container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously or recirculate waterwith the pump for2 minutes. Rinse all interiorsurfaces. Pour orpump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times. Once container is rinsed, offerfor recycling ifavailable or puncture and dispose ofin a sanitary landfill.

Refillable Containers Refillable container

- Referto Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs infonTIation as follows. Refill this containerwith pesticide only. Do not reuse this containerfor any other purpose. After emptying product from container,either retum containerto Bayer CropScience per instructions from Bayer CropScience CustomerService Center (t-800-527-4781) or rinse and either recycle ordispose ofthe container as follows:
Bottom Discharge IBC (e.g. -Schuetz Caged IBC or SnyderSquare Stackable) Pressure rinsing the container before final disposal is the responsibility ofthe person disposing ofthe container. Cleaning before refilling is the responsibility ofthe refiller. To pressure rinse the container before final disposal, empty the remaining contents from the IBC into application equipment ormix tank. Raise the bottom ofthe IBC by t.5 inches on the side which is opposite ofthe bottom discharge valve to promote more complete product removal. Completely remove the top lid ofthe IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure rinSing. Continue pressure rinsing for2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar Bt20, Drums, Kegs). Triple rinsing the container before final disposal is the responsibility ofthe person disposing ofthe container. Cleaning before refilling is the responsibility ofthe refiller. To triple rinse the containers before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the container at least to percent full with water. Agitate vigorously or recirculate water with the pump for2 minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeatthis proCedure 

### two more times. Once container is rinsed, offerfor recycling ifavailable or puncture and dispose ofin a sanitary landfill.

Refillable Containers End users are authorized to remove tamperevident cables as required 

### to remove the product from the container unless the container is equipped with one way valves and refilling or retuming is planned. Ifthis is the case, end users are not authorized to remove tamper evident cables, one way valves orclean container. See Container Disposal instructions under Storage and Disposal. ( ( • C 

### '" 

## , Enclosed is an EPAForm 8570-1, one copy ofthe revised

## PREPTM brand Ethephon

## PLANi'( , ' REGULATOR FOR COTTON (Reg. No.: 264- 380) label forreview. and an extra page (with theContainerDisposal Section) where the revised/new textis highlighted.
This amendment is consistentwith the guidance inPRNotice 2007-4 and EPA's alternative language acceptance letterto BayerCropScience datedNovember 10, 2009. No other changeshave beenmadetothelabeling orthe Confidential Statement ofFormula for this prQG.uct: ' I understand thatit is a violation of 18 U.S.C. Section 1001 to willfully make any false statement to EPA. I furtherunderstand thatifthe amended label is not consistent with therequirements of4::!

2 

### , 

## , , , 

## • "( ,

" ,

### CFR §§156.1O, 156.140, 156.144, 156.146 and 156.156, this productmaybe in violation ofFIFRA and I may be subjected

### to enforcement action and penalties WIder Section 12 and 14 ofFIFRA".
Please contact me 

## ifyou shouldhave further questions. Sincerely,

Laura Phelps Regulatory Affairs, Herbicides & 

### PGRs Bayer CropScience 2 T. W. Alexander Drive RTP, NC 27709 office: 919-549-2302 mobil:919-352-8075 email: 1aura.phelps@bayercropscience.com

-, , C ,_



## -,. ,

3 ,:' , 

### '" '

### ( 

# PREpTM brand Ethephon PLANT REGULATOR FOR COTTON FOR COMMERCIAL USE OR AGRICULTURAL USE ONLY. NOT FOR RESIDENTIAL USE. ACTIVE INGREDIENT: Ethephon (2-chloroethyJ) phosphonicacid"

..........................................................................................................................................39.9% 

### INERTINGREDIENTS:

....................................................................................................................................................................................60.1% "This Product contains 4 pounds ethephon pergallon. 

## EPA Reg. No. 264·380 EPA Est. No. 264·PA·01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO NOTifiCATION 

# 1 920m Si 

### usted no entiende la etiqueta, busque a alguien para quese la explique a usted en

# det~y'6 (If

### you do not understandthe label, find someone to explain 

### it

### to you in detaiL) 

### ForMEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours ADay 1-800-334-7577 For PRODUCTUSE Information Call1-866·99BAVER (1-866-992-2937) 

# FIRST AID IFIN EYES: 

# • Hold eye open and rinse slowly and gently with waterfor 15-20 minutes. 

# • Remove contact lenses, ifpresent, afterthe 

### first 5 minutes, then continue rinsing eye. 

## • Call a poison control center or doctorfortreatment advice. IFON SKIN OR 

# • Take off contaminated clothing. CLOTHING: Rinse skin immediately with plenty ofwaterfor 15-20 minutes. 

# • • Call a poison control center ordoctorfor treatmentadvice. IF SWALLOWED: 

## • Immediately call a p:lison control center ordoctorfortreatment advice. 

# • Do not inducevomiting unless told to doso bya poison control center ordoctor. 

## • Have person sipa glass ofwater ifable

### to swallow. 

## • Do notgive anythina by mouthto an unconscious person. For MEDICAL Emergencies Call 24 Hours A Day1-800-334·7577. Havethe Droduct containerorlabel with you when ca/5na a DOison control center ordoctororaoina fortreatment. 

### NOTE TO PHYSICIAN: Treatsymptomatically. Consideration should be given to the possibility that overexposure to materials other than this product may have occurred. No specific antidote is available. Probable mucosal damage may contraindicate the use of oastric lavaoe.

,. e 0 c 

# PRECAUTIONARY STATEMENTS ," 

## , 

## DANGER HA2ARDS TO HUMANS AND DOMESTIC ANIMALS Corrosive. Causes irreversible eye damage and skin irritation. skin, oron clothing. Harmful orfatal jfswallowed. Avoid contamination offood. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) ., i

Harmful Ifswallowed orabsorbed through skin. Do not get in eyes, D

.. '1< <

Applicators and other handlers mustYVear long-sleeved shirt and long pants, chemical resistant gloves made ofany Waterproof material (such as Nitrile, Butyl, Neoprene and/or Barrier Laminate), shoes plus socks and protective eyewear. '.' , . When handlers use closed systems, enclosed cabs, oraircraft in a mannerthat meets the requirements listed in the

### W~rk~ Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d) (4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS.

## ( 

## (

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this product's concentrate. Do not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. Ifno such instructions for washables, use detergent and hotwater. Keep and wash PPE separately from other laundry. 

## User Safety Recommendations Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. Usersshould remove clothing immediately ifpesticide gets inside. Then wash thoroughly and puton clean clothing. Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean clothimt Washthe outside ofoloves before removino. 

## ENVIRONMENTAL HAZARD Avoid spray driftto nearby crops as this product may cause temporary modifications in plant growth. Do not contaminatewater used for irrigation or domestic purposes. 

### 00 not apply directly

### to water, orto areas where surface water is present or

### to intertidal areas below the mean high water mark. Do not contaminate waterwhen disposing ofequipmentwashwaters. 

### 00 notexceed the rate of PREpm brand Ethephon Plant Regulator for Cotton per acre per year recommended on this label. 

## SPRAY DRIFT Avoid spray drift. 

### 00 not apply when weather conditions may cause drift. 

### 00notallowthis product to drift on to non-target areas. Drift may result in illegal residues or injury 

### to adjacent crops and vegetation, in the form of leaf yellowing and defoliation. To avoid spray drift, DO NOT apply aerially when wind speed is greater than 

### 10 mph orduring periods oftemperature inversions. Use oflargerdroplet size 

### 'Mil also reduce spray drift. AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipment-and-weather-related factors determinethe potential for spray drift The applicator is responsible for considering all these factors when making decisions. The following drift management reqUirements must be followed toavoid off-target movement from aerial applications to agricultural field crops. These requirements do not apply to forestry applications, public health uses or to app6cations using dryformulations. 1. The distance ofthe outer most nozzles on the boom mustnotexceed 

### 314the length ofthe wingspan or rotor. 2. Nozzles mustalways point backward parallel with the airstream and never be pOinted downwards more than 45 degrees. Where states have more stringent regulations, they should be observed. The applicator should be familiar with and take into accolB1t the information covered in the Aerial Drift ReductionAdvisory below: 

## AERIAL DRIFT REDUCTION ADVISORY [ThiS section isadvisory in nature and does not supersede the mandatory label requirements'. INFORMAnON ON DROPLETSIZE The most effective way to reduce drift potential is to apply large dropiets. The best drift management strategy is to apply the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but 'NIll not prevent drift if applications are made improperly, or under lB1favorable environmental conditions (See VVlnd, Temperature and Humidity, and Temperature Inversions). CONTROllING DROPLETSIZE Volume

- Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure

- 

### 00 not exceed the nozzle manufacturer's recommended pressures. For many nozzletypes lower pressure produces larger droplets. When higher flow rates are needed, use higherflow rate nozzles instead ofincreasing pressure. Number of nozzles

- Usethe minimum number ofnozzles that provide uniform coverage. Nozzle Orientation

- Orienting nozzles so that the spray is released parallel 

### to the airstream produces larger droplets than other orientations and isthe recommended practice. Significant deflection from horizontal will reduce droplet size and increase drift potential. Nozzle Type

- Use a nozzle type that is designed for the intended application. With most nOZZle types, narrower spray angles produce larger droplets. Consider using low-dr'ift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the lowest drift. BOOM LENGTH For some use pattems, reducing the effective boom length to less than 

### 3f4 of the wingspan or rotor length may further reduce drift without reducing swath width.

2

## (

APPUCATION HEIGHT Applications should not be made at a height greaterthan 10 feet above thetop ofthe target plants unless a greater height is required for aircraft safety. Making applications atthe lowest heightthat issafe reduces exposure ofdroplets to evaporation and wind. 

### SWATHADJUSTMENT When**app~cations** are madewith a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges ofthe field, the appficator should compensate for this displacement by adjusting the path ofthe aircraft upwind. Swath adjustment distance should increase, with increasing drift potential (higherwind, smaller drops, etc.). 

### WIND Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type determine drift p:Jtentia at any given speed. Appfication should be avoided below 2 mph due to variable wind direction and high inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and howthey affect spray drift 

### TEMPERATUREAND HUMIDITY When making applications in low relalive humidity, set up equipment to produce larger droplets to compensate for evap:Jration. Droplet evap:Jration is mostsevere when conditions are both hotand dry. 

### TEMPERATURE INVERSIONS Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air mixing, which causes small suspended droplets

### to remain in a concentrated cloud. This cloud can move in unpredictable directions due to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with altitude and are common on nights 

### with limited cloud cover and light

### to no wind. They begin to form asthe sun sets and often continue intothe morning. Their presence can be indicated by ground fog; however, iffog is not present, inversions can also be identified by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under lowwind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. 

### SENSmVEAREAS The pestic'lde should only be applled when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive areas). 

# DIRECTIONS FOR USE It isa violation of Federal Jaw

### to usethis product in a manner inconsistentwith 

### its labeling. Do notapply this product ina waythatwill contactworkers orother persons, eitherdirectly orthrough drift. Only protected

handlers may be in the area during application. Forany requirements specifictoyourState orTribe, consult

### the agency responsible for pesticide regulations. Read entire label before using this product 

## AGRICULTURAL USE REQUIREMENTS Usethis product only in accordance

### with its labeling and

### with theWorker Protection Standard, 40 CFR part 170. This standard contains requirements for the protection of agrirultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. 

### It contains requirements for training, decontamination, notification, and emergency assistance. 

### It also contains specific instructions and exceptiOns pertaining tothe statements on this label about personal protective equipment (PPE). notification

### to workers and restricted-entry interval. The reqUirements in this box only apply to uses ofthis productthat are covered by the Worker Protection Standard. Do not enter orallowworker entry into treated areas duringthe restrided-entry interval (REI) of48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches peryear. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical resistant gloves made ofany waterproofmaterial, such as nitrile. butyl, neoprene, orbarrier laminate, chemical resistant footwear plus socks, and protective eyewear. Foroverhead exposure, chemical-resistant headgear isalso required. Notifyworkers ofthe application bywarning them orally and postin9.., warning signs at entrances

### to treated areas.



### 3

## STORAGE AND DISPOSAL Do not contaminate water, food, orfeed by storage ordisposal. PESTICIDE STORAGE 

## (

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED; Ifcontainer is broken orcontents have spilled, follow all precautions indicated above and clean up immediately. Before cleaning up, put on fun length trousers, long sleeved shirt, protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth orother suitable material and dispose ofwaste atan approved waste disposal facility. PESTICIDE DISPOSAl Pesticide wastes are acutely hazardous. Improperdisposal ofexcess pesticide, spray mixture, or rinsate is a violation of Federal law. If these wastes cannot 

### be disposed 

### of by use according to label instructions, contact your State Pesticide or Environmental Control Agency orthe HazardousWaste representative atthe nearest EPA Regional Office forguidance. CONTAINER DfSPOSAL Rigid, Nonwrefilfable containers smalf enough toshake (i.e., with capaCities equal 10 or less1han 5 galfons) Non-refillable container. Do not reuse or refill thiscontainer. Triple 

### rinse or pressure 

### rinse container (orequivalent) promptly after emptying. Triple rinse asfollows: Emptythe remaining contents intoappfication equipment ora mixtank and drain for 10seconds after theflowbegins

### to drip. Fill the container 1/4fulf with waterand recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank orstore rinsatefor later use or disposal. Drain for 10 seconds aftertheflow begins to drip. Repeatthis procedure

### two more times. Once container is 

### rinsed, offerfor recycling ifavailable or puncture and dispose ofina sanitary landfill. RIgId Nonwreftllable containers

### tha1 are too large toshake (i.e., with capaCities greaterthan 5 gallons or50 Ibs) Non-refillableContaIners Non-refillable containers

- Do not reuse or refill this container. Referto Bottom Discharge IBC orTop Discharge IBC, Drums, Kegs information as follows. Bottom Discharge IBC (e.g.

- Schuetzcaged lBe orSnyder SquareStackable) Pressure rinsing the container before final disposal is the responsibility 

### ofthe person disposing ofthe container. To pressure rinse the container before final disposal, empty the remaining contents from the IBC intoapplication equipment or mix tank. Raise the bottom of the IBC by 1.5 inches onthe sidewhich is opposite ofthe bottom dischargevalve to promote more complete product removal. Completely remove the top lid ofthe IBC. Usewater pressurized to 

## at least 4D PSIto rinse all interior portions. Continuously pump or drain rinsate into application equipment orrinsate collection system whHe pressure rinsing. Continue pressure rinsing for2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 NextGen, Bonar B120, Drums, Kegs). Triple rinsing the container before final disposal isthe responsibmty of.the person disposing ofthe container. To triple rinse the container before final disposal, empty the remaining contents from this containerintoapplication equipment or mix tank. Fill the container at feast 10percentfulf

### -....ith water. Agitate vigorously or recirculate waterwith the pump for 2 minutes. Rinse alf interior surfaces. Pouror pump 

### rinsate into application equipment or rinsate COllection system. Repeat this procedure

### two moretimes. Once container is rinsed, offerfor recycling ifavailable or puncture and dispose ofin a sanitary landfill. Refillable Containers Refillable container

- Referto Bottom Discharge IBC orTop Discharge .fBC, Drums, Kegs information as follows. Refill this container with pesticide only. 

### Do not reuse this containerforany other purpose. After emptying product from container, either retum containerto Bayer CropScience 

### per instructions from Bayer CropScience Customer Service Center (1-800-527-4781) or rinse and either recycle or disp::lse ofthe containeras follows: Bottom Discharge IBC (e.g.

- SchuetzCaged IBC or Snyder Square Stackable) Pressure rinsing the container before final disposal isthe responsibility ofthe person disposing ofthe container. Cleaning before refilling is the responsibility ofthe refiller. To pressure rinse the container before final disposal, emptythe remaining contents from 

### the IBC into application equipment or mix tank. Raise the bottom ofthe IBC by 1.5 inches on the side which is opposite 

### ofthe bottom discharge valve to promote more complete product removal. Completely remove the top lid ofthe IBC. Usewater pressurized to at least 40 PSI to rinse all interior portiOns. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. Top DIscharge ISC, Drums, Kegs {e.g.- Snyder 120 NextGen, Bonar B120, Drums, Kegs}. Triple rinsing the container before final disposal isthe responsibifity ofthe person disposing ofthe container. Cleaning before refilling is the resp::lnsibility ofthe refiller. To triple rinse the containers before final disposal, empty the remaining contents from this container into application equipment or mix tank. Flff the container at least 10 percent full with water. Agitate vigoroUSly or recirculate water wilh the pump for2 minutes. Rinse all interior surfaces. Pouror pump rinsate into application equipment orrinsate collection system. Repeat this procedure 

### two moretimes. Once container is rinsed, offerfor recycling ifavailable or puncture and dispose ofin a sanitary landfill.

4

### (

Refillable Containers 

### End users are authorized

### to remove tamperevident cables as required to remove the product from the container unless the container is equipped with one way valves and refilling or returning is planned. Ifthis is the case, end users are not authorized

### to remove tamper evident cables, one

### way valves orclean container. See Container Disposal instructions under Storage and Disposal. 

### GENERALINFORMATION A foliar spray of PREpTM brand Ethephon Plant Regulator for Cotton will accelerate opening of mature unopened cotton bolls and enhance defoliation which can result in earlier harvest 

### with an increased recoverable yield. PREpTM brand Ethephon Plant Regulator 

### forCotton treatment allows increased efficiency from a once-over harvest. Some premature drop of small, immature bolls may be associated with treatment. Do not apply before sufficient, mature, unopened bolls have developedto produce the desired yield ofcotton. A boll is mature when it is too hard to be dented when squeezed betweenthumb and fingers, too hard to be sliced with a sharp knife, andwhenthe seed coat becomes light brown incolor. For 

### best results, thorough and uniform spray coverage is required. 

## tt is essentia! that the bolls are contacted by the spray to obtain optimum boll opening. Observe treated fields closely. Harvest 

### at optimum boll opening and defoliation, generally 

### 14 to 

### 21 days after treatment. Sustained cold weather with average day and night temperatures 

### ci 65°F or lower after treatment 

### with PREpTM brand Ethephon Plant RegUlatorforCotton will de!ay the boll opening response. DO NOT APPLY PREpTM BRAND ETHEPHON PLANT REGULATOR FOR COTTON !F RAIN IS EXPECTED W!THIN 6 HOURS. Rainfall within 6 hours ofapplication may reduce product performance. Certified cotton seed growers shou!d observe boll and seed maturity before treatment VYith PREPTM brand Ethephon Plant Regulatorfor Cotton. Bolls not completely mature might open with treatment 

### of PREpTM brand Ethephon Plant Regulator for Cotton giving 10\oVer quality seed. IMPORTANT: Do notapply PREPTM brand Ethephon Plant Regulatorfor Cotton through any type of irrigation system. 

### SPRAY PREPARATION Add 

### 1/2 to 

### 3/4 ofthe required amount ofwater to the spray tank. Start agitation. Addthe required amount of PREpTM brand Ethephon Plant Regulator for Cotton, and the remaining amount ofwater. Prepare only as much spay solution as can be used on the day 

### of mixing. Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment, or any airplane parts. ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OFWATER. Use ofa nurse tank is highly recommended for avoiding possible spills ofconcentrated formulation on spray equipment or any airplane 

### parts. EQUIPMENTClEANING Spray depOSits 

### of PREpTM brand Ethephon Plant RegulatorforCotton, when left on aircraft acrylic plastic type windshields for longer than 

### 1 hour, may react with this material, forming an opaque film orspots on the surfacewhich cannot be removed by washing with waterorany other cleaner. Rinsewindshields

### with waterimmediately· after each tankload of PREpTM brand Ethephon Plant Regulator forCotton has been applied. Thoroughly rinse the aircraftwith clean water after each day PREpTM brand Ethephon Plant Regulatorfor Cotton is appfled. PREpTM brand Ethephon Plant Regulatorfor Cotton may also affect certaIn paints, and ifaccidental depoSits on painted objects such as cars, trucks, agriCUltural equipment, etc. occurs, these objects should be rinsed with waterassoon as possible (within 

### 1 hcur) to prevent permanent staining 

### ofthe painted surface. Because of the acidic nature of this product, prolonged exposure to spray deposit 

### wi!! damage acrylic plastiCS, certain paints, and metals. Rinse thoroughly 

### with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted surfaces within an hourafter exposureto spray deposits. 

### At 

### the end ofeach day, rinse thoroughly with a detergent and water all 

### the metal parts 

### ofthe aircraft andthe associated spray equipment exposed tothe spray depOSits.

5BOllOPENING

CONDITIONS EXPECTED 

### 5-7 DAYS AFTER

TREATMENT
Hotand dry 80"F or higher Dry with temperature 75"Fto 80"F Cool but higher than 65"F Rank cotton Rates FOf Boll Opening

PREpTh! brand Ethephon ONE GALLON OF Plant Regulatorfor Cotton PREpTh! brand Ethephon Plant Regulator for Cotton QUARTS/ACRE TREATS

1.0 (1.0 Ib aJ.) 

### 4 Acres 1.5(1.5IbaJ.) 2.5 Acres
2.0 (2.0 Ib aJ.) 2 Acres 2.0 (2.0 Ib aJ.) 2 Acres SPRAY VOLUME GAl.IACRE GROUND AIR

15to 50 2 to 5* 15to 50 2 to 5*

15to 50 2 to 5* 25 to 50 

### 5 *NOTE: For California and Arizona use a volume ofno less than 5 gallons per acre for aerial applications
TIme 

### ofApplication (8011 Opening) Apply when there are sufficient mature unopened bolls to produce the desired yield, but no later than when 60% ofthe bolls are opened (see General Information section on howto test for boll maturity). Do nottank mix PREpTM brand Ethephon Plant Regulator for Cotton with a desiccant ifthe cotton is to be spindle harvested. 

## PRECONDITIONING FOR DEFOLIATION
Rates For Preconditioning For Defoliation

CONDITIONS EXPECTED 

### 5-7 DAYS AFTER

TREATMENT Hotand dry BO"F or higher Cool but higherthan 65"and alsofor rank cotton PREpTM brand Ethephon Plant Regulator for Cotton QUARTS/ACRE

0.5 (0.5 IbaJ.) 1.0 (1.0 Ib a.i.) ONE GALLON OF PREpTM brand Ethephon Plant Regulator for Cotton TREATS 

### 8 Acres 4 Acres SPRAY VOLUME GAL.1ACRE GROUND AIR

15 to 

### 50 15to50 2t05* 

### 2 to 5*
*NOTE: For California and Arizona use a volume of no less than 5 gallons per acre for aerial applications.
Time 

### ofApplication (Preconditioning) Apply PREpTh! brand Ethephon Plant Regulatorfor Cotton4 to 7 days prior toapplication ofdefoliant ortank mixed

### with the defoliant (see section on Compatibility). Do nottank mix PREpTM brand Ethephon Plant Regulator for Cotton with desiccants unless plant desiccation is required.
Pre-treatment

### With Defoliants Priorto PREpTM brand Ethephon Plant Regulatorfor Cotton Treatment If the cotton is overly rank or laying down in the middles and good spray coverage of the bolls with PREpTM brand Ethephon Plant Regulator for Cotton is difficult, a pretreatment with defoliants will be useful to improve boll coverage with PREpTM brand Ethephon Plant Regulator for Cotton. Use dosage rates of PREpTM brand Ethephon Plant Regulator for Cotton recommended for boll opening. Read and observe all appropriate label use directions and precautions for the defoliant used. Do not use a defoliant before there are sufficient mature unopened bolls to produce the desired yield (see General Information section on howto test for Boll Maturity). COMPATIBIUTY PREpTM brand Ethephon Plant Regulator for Cotton is compatible with DEF, FOLEX, DROPP, HARVADE, METHYL PARATHION, GUTHION AND MALATHION, and may be applied in sequence or as a tank mixture (DO NOT TANK MIX WITH DEFOLIANTS OR DESICCANTS IN CALIFORNIA AND ARIZONA). In some cases slight reduction in boll opening response has 

### been observed when tank mixes 

### with defoliants were used. Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to 10 minutes. Read and observe all appropriate label use directions and precautions forthe defoliants and insecticides used.



### 6

### (

PRECAUTION: 

### NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpThl BRAND ETHEPHON PLANT REGULATOR FOR COTTON WITH DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS 

### WHICH ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. DO NOT MIX PREpTM BRAND ETHEPHON PLANT REGULATOR FOR conON WITH AMMONIUM THIOSULFATE SUCH TANK MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES.
WHEN TO HARVEST: 

### Do not harvest cotton sooner than 7 days after a treatment 

### with PREPTM brand Ethephon Plant Regulator for Cotton. Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the full advantage 

### of the 

### treatment and too late a harvest may result in reduced quality and foss oflintwhich will drop from the plant. USE UMITATIONS 

### Do not 

### exceed a maximum of 2.0 lb. ethephon active ingredient per acre per year through combined or repeated uses of any ethephon products. Boll Opening: Do not tank mix PREpTM brand Ethephon Plant Regulator for Cotton with a desiccant ifthe cotton is to be 

### spindle harvested. Pre-Condition for Defoliation: Do 

### not tank mix PREpTM brand Ethephon Plant Regulator for Cotton with desiccants unless plant desiccation is required. 

### Do not use a defoliant before there is sufficient mature unopened bolls to produce the desired yield (see General Information section on howto testfor boll maturity. Do not plant another crop within 30 days aftertreatment. USE PRECAUTIONS 

### Avoid spray drift to nearby crops as this productwill cause modifications in plant growth. Plant injury or reduced yields will result. Mix only the amountofspray you expectto use each day. Do not allow mixed solutionto stand overnight.

7

### { 

# !

IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer ofWarranties and Limitations of liability before usingthis product. Ifterms are not acceptable, retum the unopened product container at once. By using this product. useror buyer accepts the following Conditions, Disclaimer of warranties and Limitations ofliability. CONDITIONS: The directions for use 

### of this product are believed 

### to be adequate and must be followed carefully. However, it is impossible to eliminate all risks associated 

### with the use ofthis product Crop injury, ineffectiveness orother unintended consequences may result because ofsuch factors as weather conditions, presence ofother materials, or the manner of use orapplication, all ofwhich are beyond the control of Bayer CropScience. All such risks shall be assumed bythe user orbuyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEl. No agent of Bayer CropScience is authorized to make any warranties beyond 

### those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT WITH APPLICABLE 

### LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAl, INCIDENTAl OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. LIMITATIONS OF LIABILITY; TO THE EXTENT CONSISTENT WITH APPLICABLE 

### LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND AlL LOSSES, INJURIES OR DAMAGES RESUL TlNG FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN 

### CONlR.OCT,**~,** TORT, 

### NEGUGEJ-.K;E, STRICT 

### lJOBIUTY OR OTI-ER'MSE, 

### SI-W.L l'K)T 

### EXCEED THE 

### Pl..JROV\SE

### PRICEPAID, ORAT

### BAYERCROPSClENCE'SEl...ECTlCNTHE REPlACEMENTOFPRODUCT.

BayerCropScience lP P.O. Box 12014, 2T.W. Alexander Drive Research Triangle Park, NorthCarolina 27709 

### 1-866-99BAVER (1-866-992-2937) PREpm brand Ethephon Plant Regulator for Cotton (PENDING) 

### 08/05/10

8

### (



## STORAGE AND DISPOSAL Do not contaminate water, food, orfeed by storage or disposal. PESTlC[DE STORAGE 

## I

Store in a cool, dry place and away from food, feed and other pesticides. [F SP[LLED: [fcontainer is broken or contents have spilled, follow all precautions indicated above and clean up immediately. Before cleaning up, put on full length trousers, long sleeved shirt, protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and dispose ofwaste at an approved waste disposal facility. PEST[CIDE D[SPOSAL Pesticide wastes are acu[ely hazardous. Improper disposal ofexcess pesticide, spray mixture, or rinsate is aviolation ofFederal law. [f these wastes cannot be disposed of by use according to label instructions, contact your State Pestic'lde or Environmenta[ Control Agency or the Hazardous Waste representative 

### atthe nearest EPA Regional Office for guidance. CONTAINER DISPOSAL Rigid, Non-refillab[e containers small enough

### to shake (I.e., with 

### capacities equal to or less than 5 gallons) Non-refillab[e container. 

### Do not reuse or refillthis container. Trip[e rinse or pressure rinse container (or equivalent) promptly after emptying. Triple rinse asfollows: Emptythe remainlng contents into**app~cation** 

### equipment ora m'lx tank and drain for to seconds after the

### flow begins

### to drip. Fill the container t/4

### full with water and recap. Shake for toseconds. Pour rinsate into application equipmentor a mix tank or store rinsate for later use or disposal. Drain for 10 seconds aftertheflow beginsto drip. Repeatthis procedure 

### two more times. Once container is rinsed, offerfor recycling 

### ifavailab[e or puncture and dispose of in a sanitary landfill. Rigid Non-refillablecontaIners thatare too large toshake {I.e., with capacities greaterthan 5 gallons or50 [bs} Non-refillableContainers Non-refillab[e containers

- Do not reuse or refill this container. Refer to Bottom Discharge IBC orTop Discharge [BC, Drums, Kegs information as fol[ows. Bottom Discharge IBC (e.g.

- Schuetz Caged IBC orSnyder Square Stackab[e) Pressure rinsing the containerbefore final disposal is the responsibility ofthe person disposing of

### the container. To pressure rinse the container before final disposal, emptythe remaining contents from the [BC into application equ'rpmert or mix tank. Raisethe bottom of the [BC by 1.5 inches on the sidev.ttich is opposite ofthe bottom discharge valve to promote more complete product removal. Comp[etely remove the 

### top lid ofthe [BC. Use waterpressurized to at [east 40 PS[ to rinse aU interior portions. Continuously pump or drain rinsate intoapplication equipment or rinsate collection system 'Nhile pressure rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the 

### lid and close bottom valve. Top Discharge IBC, Drums, Kegs {e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs}. Trip[e rinsing the container beforefina[ disposal isthe 

### responsibility of

### the person disposing of

### the container. Totriple rinse the container before final disposal, empty the remainillJ contents 

### from this container into application eqUipment or mix tank. Fillthe container

## at [east topercentfull with 

### water. Agitate vigorously or recirculate waterwith

### the pump for

### 2 minutes. Rinse all interior surfaces. Pouror pump**ri~te** 

### into application equipment or**rin~e** 

### C9!tection system. Repeatthis procedure 

### two more times. Once containeris rinsed, offerfor· recycling if

### availab[e or puncture and dispOse of

### In asanitary landfill. Refillable Containers Refillable container- Referto BottQm Discharge IBC or Top DischargeJaC, Drums, Kegs infonnation as follows. Refill this container with 

### pesticide only. Do not reuse this containerforany otherpurpose. After emptying product from container, either return container to Bayer CropScience perinstructionsfrom 

### Bayer CropScience Customer Service Center (1-800-527-4781) or rinse and either recycle or dispose of

### the containerasfollows: Bottom Discharge IBC (e.g.

- Schuetz Caged IBC orSnyder Square Stackable) Pressure 

### rinsing the containerbefore fina[ disposal Is 

### the responsibility ofthe person disposing of

### the container. Cleaning before refilling is the responsibility ofthe refiller. To pressure rinse the containerbefore final dlsposa[, emptythe remaining contents from the [BC into application equipment ormix tank. Raise the bottom ofthe [BC by 1.5 inches on the side

### 'Nhich is opposite of

### the bottom discharge valve 

### to promote more complete product removal. Comp[etely remove the 

### top lid of

### the [BC. Usewater pressurized 

### to at least40 PSI to rinse all interior portions. ContinuousfY pump or drain rinsate into application equipment or rinsate collection system 'Nhile pressure rinsing. Continue pressure rinsing for

### 2 minutes or until rinsate becomes dear. Reptace the [jcf 

### and close bottom valve. Top Discharge IBC, Drums, Kegs (e.g._Snyder 120 Next Gen, Bonar B120, Drums, Kegs). Triple rinsing the container before final disposal is 

### the responsibility of

### the person disposing of

### the container. Oeaning before refiDing is the responsibility of

### the 

### refiller. Totriple rinse the containers before final disposal, emptythe remaining contents 

### from this containerinto application equipment or mix tank. An the container at [east 10 percent full with 

### water. Agitate vigorousfy or recirculate water viilh the pump for

### 2 minutes. Rinse all interiorsurfaces. pouror pump rinsate into application equipment or rinsate coUection system. Repeatthis procedure 

### two moretimes. Once container is rinsed, offerfor recycling if

### availab[e or puncture and dispose of

### in asanitary landfill.

4Refillable Containers End users are authorized to remove tamperevident cables as required to remove the product from the container unless the containeris equipped

### with one way valves and refilling or returning is planned. Ifthis isthe case, end users are not authorized to removetamper evident cables, oneway valves orclean container. 

### SeeContainer Disposal instructions under Storage and Disposal. 

### GENERAL INFORMATION A foliar spray of PREpTM brand Ethephon Plant Regulator for Cotton will accelerate opening of mature unopened cotton bolls and enhance defoliation which can result in earlier harvest with an increased recoverable yield. PREPThl brand Ethephon Plant Regulator for Cotton treatment allows increased efficiency

### from a once-over harvest. Some premature drop of small, immature bolls may be associated with treatment. Do not apply before sufficient, mature, unopened bolls have developed 

### to produce the desired yield 

### ofcotton. 

### A boll is mature when it is too hard 

### to be dented when squeezed between thumb and fingers, too hard to 

### be sliced with a sharp knife, andwhen the seed coat becomes light brown in color. For best results, thorough and uniform spray coverage is required. It is essential that the bolls are contacted by the spray 

### to obtain optimum boll opening. Observe treated fields closely. Harvest at optimum boll opening and defoliation, generally 

### 14 to 

### 21 days after treatment. Sustained cold weather with average day and night temperatures of 65°F or lower after treatment with PREpTM brand Ethephon Plant Regulatorfor Cotton will delay the boll opening response. DO NOT APPLY PREpTM BRAND ETHEPHON PLANT REGULATOR FOR COTTON IF RAIN IS EXPECTED WITHIN 

### 6 HOURS. Rainfall within 

### 6 hours ofapplication may reduce product performance. Certified cotton 

### seed growers should observe boll and seed maturity before treatment with PREpTM brand Ethephon Plant Regulatorfor Cotton. Bolls not completely mature might open 

### with treatment 

### of PREpTM brand Ethephon Plant Regulator for Cotton giving lower quality seed. IMPORTANT: Do notapply PREpTM brand Ethephon Plant Regulatorfor Cotton through anytype of irrigation system. SPRAY PREPARATION 

### Add 112 to 

### 314 ofthe required amount 

### ofwaterto the spray tank. Start agitation. Add the required amount of PREpm brand Ethephon Plant Regulator for Cotton, and the remaining amount of water. Prepare only as much s]:X"8y solution as can be used on the day of mixing. Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment, or any airplane parts. ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OFWATER. Use ofa nurse tank is highly recommended for avoiding possible spills ofconcentrated formulation on spray equipment orany airplane parts. EQUIPMENTCLEANING Spray deposits 

### of PREpTM brand Ethephon Plant RegulatorforCotton, when lefton aircraftacrylic plastiC type windshields for longer than 1 hour, may react

### with this material, forming an opaque film orspots on the surface which cannot 

### be removed by washing with waterorany other cleaner. Rinse windshields with water immediately after each tankload 

### of PREpTM brand Ethephon Plant Regulator forCotton has 

### been applied. Thoroughly rinse the aircraftwith clean**~~er** aftereadl day PREp1"M brand Ethephon Plant Regulatorfor Cotton is applied. PREpTM brand Ethephon Plant RegulatorforCotton may also 

### affect certain paints, and 

### ifaccidental deposits on painted objects such as cars, trucks, agricultural eqUipment, etc. occurs, these objects should be rinsed 

### with wateras soon as possible (within 1 hour)

### to prevent permanent staining ofthe painted surface. Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastics, certain paints, and metals. Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted surfaces within an hourafter exposure 

### to spray deposits. Atthe end ofeach day, rinse thoroughly with a detergent and waterall the metal parts ofthe aircraft and the associated spray equipment exposed to the spray deposits.



### 5