**Certification      Pursuant to Section 13a-14 of the Securities Exchange Act of 1934      of**

**Thomas      L. Wegman**

**(President,      Principal Executive Officer and Principal Financial      Officer)**

|   | 1. | I                have reviewed this Form 10-QSB for the quarterly period ended March                31,                2007 (the                “report”) of BioSpecifics Technologies Corp.                (“registrant”); |
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|   | 2. | Based                on my knowledge, the report does not contain any untrue statement                of a                material fact or omit to state a material fact necessary to make                the                statements made, in light of the circumstances under which such statements                were made, not misleading with respect to the period covered by this                report; |
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|   | 3. | Based                on my knowledge, the financial statements, and other financial information                included in this report, fairly present in all material respects                the                financial condition, results of operations and cash flows of the                registrant as of, and for, the periods presented in this                report; |
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|   | 4. | The                small business issuer’s other certifying officers and I are responsible                for establishing and maintaining disclosure controls and procedures                (as                defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal                control over financial reporting (as defined in Exchange Act Rules                13a-15(f) and 15d-15(f)) for the small business issuer and                have: |
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|   | (a) | Designed                such disclosure controls and procedures, or caused such disclosure                controls and procedures to be designed under our supervision, to                ensure                that material information relating to the registrant, including its                consolidated subsidiaries, is made known to us by others within those                entities, particularly during the period in which this report is                being                prepared; |
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|   | (b) | Evaluated                the effectiveness of the registrant’s disclosure controls and procedures                and presented in this report our conclusions about the effectiveness                of                the disclosure controls and procedures, as of the end of the period                covered by this report based on such evaluation;                and |
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|   | (c) | Disclosed                in this report any change in the registrant’s internal control over                financial reporting that occurred during the registrant’s most recent                fiscal quarter (the registrant’s fourth fiscal quarter in the case of an                annual report) that has materially affected, or is reasonably likely                to                materially affect, the registrant’s internal control over financial                reporting; and |
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|   | 5. | The                small business issuer’s other certifying officers and I have disclosed,                based on our most recent evaluation of internal control over                financial reporting, to the registrant’s auditors and to the audit                committee of the registrant’s board of directors (or persons performing                the equivalent functions): |
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