Master Label

Page 1 of 10 Dec. 4 , 201 2 

# MADEX Twin

Insecticidal Virus **Sublabel A : A** **gricultural Use Sublabel B:**  **Residential Use**  **Ac tiv** **e Ingredient*:** Cydia pomonella granulovirus isolate V22 0. 06% **Other Ingredients:** 9 9.94% **Total:** 100.00% *Contains a minimum of 3x10 1 3 viral occlusion bodies per li ter. **KEEP OUT OF**  **RE AC**  **H OF CHILDREN** 

# CAUTION EPA Reg. No.: 69553 - EPA Est. No.: Manufactured by: Andermatt Biocontrol AG

Stahlermatten 6 CH -6146 Grossdietwil SwitzerlandMaster Label

Page 2 of 10 Dec. 4 , 201 2 

# SUBLABEL A: Agricultural Use 

# MADEX Twin Biological Insecticide for Control of the Codling Moth and Oriental Fruit Moth **Ac tiv** **e Ingredient*:** Cydia pomonella granulovirus isolate V22 0. 06% **Other Ingredients:** 9 9.94% **Total:** 100.00% * Contains a minimum of 3x10 1 3 viral occlusion bodies per l iter. **KEEP OUT OF REA**

**CH OF CHILDREN** 

# CAUTION **SEE SIDE /INSIDE**  **PA NEL FOR A** **DDITIONA L PRECA** **UTIONA RY STATEMENTS** 
Net Contents: Lot No.: EPA Reg. No. 69553 - EPA Est. No. Manufactured by: Andermatt Biocontrol AG

Stahlermatten 6 CH -6146 Grossdietwil SwitzerlandMaster Label

Page 3 of 10 Dec. 4 , 201 2 **PRECA UTIONA** **RY STA TEMENTS**  **H azards To Humans and**  **Domestic A nimals**  **CA UTION**  **.** Causes moderate eye and skin irritation. Avoid contact with skin, eyes or clothing. Wa sh thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco , or using the toilet

. Remove and wash contaminated clothing before reuse.

**PERSONA L PROTECTIVE EQUIPMENT (PPE)**  Applicators and other handle rs must wear:  long - sleeved shirt and long pants  waterproof gloves  shoes plus socks Follow manufacturers’ instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately fro m other laundry. Mixers/loaders and applicators must wear a dust/mist filtering respirator meeting NIOSH standards of at least N - 95, R- 95 or P - 95. Repeated exposures to high concentrations of microbial proteins can cause allergic sensitization. **Engineeri ng Controls**  Wh en handlers use closed systems or enclosed cabs in a manner that meet the requirements listed in the Wo rker Protection Standard (WP S) for agricultural pesticides [40 CFR 170.240(d)(4 - 6)], the handler PPE requirements may be reduced or modifie d as specified in the WP S. IMPORTANT: W hen reduced PPE is worn because a closed system is being used, handlers must provide all PPE specified above for “applicators and other handlers” and have such PPE immediately available for use in an emergency, such as a spill or equipment breakdown. **FIRST A ID**  **If in ey** **es :**   Hold eye open and rinse slowly and gently with water for 15 - 20

minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing.  Call a poison control center or doctor for treatment advice. **If on skin:**  Take off contaminated clothing.

 Rinse skin immediately with plenty of water for 15 - 20 minutes.  Call a poison control center or doctor for treatment advice.

**HOT LINE NUMBER** Have the product container or label with you wh en calling a poison control center or doctor, or going for treatment. You may also contact the National Poison Control Hotline at 1 - 800 - 222 - 1222 for emergency medical treatment information.Master Label

Page 4 of 10 Dec. 4 , 201 2 **Environmental Hazards** For terrestrial uses: Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not contaminate water when cleaning equip ment or disposing of equipment wash waters or rinsate. **DIRECTIONS FOR USE** It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Do not apply this product in a way that will contact workers or other persons eith er directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the State or Tribal agency responsible for pesticide regulation. **Ag ricultural Use Requirements**  Use t his product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR Part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries and greenhouses, and handlers of agricult ural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), and restricted entry intervals (REI). The requirements in this box only apply to uses of this product that are covered by the Wo rker Protection Standard. Do not enter or allow worker entry into treated areas during the restricted entry interval (REI) of 4 h ours unless wearing appropriate PPE. PPE required for early entry to treated areas that is permitted under the Wo rker Protection Standard and that involves contact with anything that has been treated, such as plants, soil or water, is: • Coveralls • W ater proof gloves • Shoes plus socks **USER SA FETY RECOMMENDA** **TIONS** Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. Remove PPE immediately after handling this product. W ash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing.Master Label

Page 5 of 10 Dec. 4 , 201 2 **G ENERA**  **L INFORMATION** MADEX Twin acts very specifically against larvae of the apple codling moth, Cydia pomonella , and the Oriental fruit moth, Grapholita molesta , as a pre - harvest biological insecticide on pome and stone fruit trees including apple, quince, pear, peach, nectarine, apricot, plum, cherry, walnut, almond , plu o t, and aprium . After in g e s tion by the larva, the virus multiplies within the cells of the host insect causing a fatal infection. Rapid virus multiplicatio n within the host cells results in cell destruction and death of the organism , typically within 3 - 7 days

. Start spraying shortly before larvae hatch from the eggs and before the larvae feed their way into the fruit. In general, one to two sprays per generation are generally sufficient. Due to unfavorable weather conditions, flight, egg laying , and hatching may extend over a longer period of time and up to 6 applications may be needed. Frequent applications at low rates may be more effective than one or two applications at high rates. **Use Restriction**

Do not apply this product through any type of irrigation system

. **MIXING AN**  **D A PPLICA** **TION INSTRUCTIONS**  Mix MADEX Twin with water and apply as a spray to fruit and foliage of trees in orchard s and nurseries

. U se water at or near neutral pH (7). **CROP RA** **TE C**  **OMMENTS** Pome and Stone fruit trees including a pple, quince, pear, peach, nectarine, apricot, plum, prunes cherry, walnut, almond , plu o t, and aprium 0.5 - 3.0 fluid

ounces per acre , depending on pest pressure a nd application fr equency . Select a spr ay volume appropriate to tree size and density of foliage. For small trees use 50 - 100 gallons of water per acre. Larger trees with denser canopies require 100 -200 gallons per acre. Consult your local Cooperative Extens ion Service if you need advice about how to attain good spray coverage in your orchard. Make at least two (2) applications of MADEX Twin per codling moth or Oriental fruit moth larval gener ation. Target small larvae early in their life cycle. Repeat as ne cessary to maintain control. MADEX Twin breaks down under direct exposure to sunlight. If moths are still flying and laying eggs, reapply after 6 - 8 sunny days (counting 2 partially sunny days as 1 sunny day).

MADEX Twin can be applied up to and includin g the day of harvest.Master Label

Page 6 of 10 Dec. 4 , 201 2 **STORA GE A**  **ND DISPOSA L**  **Do not contaminate water, food or feed by storage and disposal. PESTICIDE STORA** **GE:** Store this product in original sealed container in a cool, dry place inaccessible to children and pets. Store at temperatures bel ow 41 °F (5 ° C) . Bioactivity may be impaired by storage above 86°F (30 ° C) . Storing the product under co ld or fr eezing temperature s will extend its shelf life. **PESTICIDE DISPOSAL:** To avoid wastes, use all material in this container by application according to label directions. If wastes cannot be avoided, offer remaining product to a waste disposal facility or pesticide disposal program (often such programs are run by state or local governments or by industry). **CONTA INER HA** **NDLING:** Nonrefillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain 10 seconds after the flow begins to drip. Fill the container 1 /4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling if available or puncture and dispose of in a sanitary landfill, or by incineration. Do not burn, unless allowed by State and local ordinances. **WA RRA**  **NTY** Andermatt Biocontrol AG warrants that the material contained herein conforms to th e description on the label and is reasonably fit for the purposes referred to in the directions for use. Timing and method of application, weather, watering practices, nature of soil, the insect problem, condition of the crop, incompatibility with other ch emicals not specifically recommended and other influencing factors in the use of this product are beyond the control of the seller. To the extent consistent with applicable law, b uyer assumes all risks of use, storage or handling of this material not in st rict accordance with directions given herein. To the extent consistent with applicable law, NO OTHER EXPRESS OR IMPLIED WA RRANTY OF THE FITNESS OR MERCHANTABILITY IS MADE.Master Label

Page 7 of 10 Dec. 4 , 201 2 

## Sublabel B: **Residential Use**  

# MADEX Twin Biological Insecticide for Control of the Codling Moth and Oriental Fruit Moth **Ac tiv** **e Ingredient*:** Cydia pomonella granulovirus isolate V22 0. 06% **Other Ingredients:** 9 9.94% **Total:** 100.00% *Contains a minimum of 3x10 13 viral occlusion bodies per liter. **KEEP OUT OF REA**

**CH OF CHILDREN** 

# CAUTION **SEE SIDE /I**  **NSIDE PA** **NEL FOR A DDITIONA** **L PRECA UTIONA** **RY STATEMENTS**
Net Contents: Lot No.: EPA Reg. No. 69553 - EPA Est. No. Manufactured by: Andermatt Biocontrol AG

Stahlermatten 6 CH -6146 Grossdietwil SwitzerlandMaster Label

Page 8 of 10 Dec. 4 , 201 2 **PRECA UTIONA** **RY STA TEMENTS**  **Hazards To Humans and Dom estic A**  **nimals CA**  **UTION.** Causes moderate eye and skin irritation. Avoid contact with skin, eyes or clothing. Wa sh thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet. Remove and wash contaminated clothing before reuse. Wh en mixing and applying this product, wear a dust mask . Repeated exposures to high concentrations of microbial proteins can cause allergic sensitization.

**ENVIRONMENTA L**  **HAZ AR**  **DS** To protect the environment, do not allow pesticide to enter or run off into storm drains, drainage ditches, gutters or surface waters. Applying th is product in calm weather when rain is not predicted for the next 24 hours will help to ensure that wind or rain does not blow or wash pesticide off the treatment area. Rinsing application equipment over the treated area will help avoid run off to water b odies or drainage systems. **DIRECTIONS FOR USE** It is a violation of Federal law to use this product in a manner inconsistent with its labeling. **GENERA L INFORMA** **TION** MADEX Twin acts very specifically against larvae of the apple codling moth, Cydia pomonella , and the Oriental fruit moth, Grapholita molesta , as a pre - harvest biological insecticide on pome and stone fruit trees including apple, quince, pear, peach, nectarine, apricot, plum, cherry, walnut, almond , plu o t, and aprium . After ingestion by the larva , the virus multiplies within the cells of the host insect causing a fatal infection. Rapid virus multiplication within the host cells results in cell destruction and death of the organism , typically within 3 - 7 days

. Start spraying shortly before larvae hatch from the eggs and before the larvae feed their way into the fruit. In general, one to two sprays per generation are generally sufficient. Due to unfavorable weather conditions, flight, egg laying , and hatching may extend over a longer period of time and up to 6 applications may be needed. **FIRST A ID**  **If in ey es:**   Hold eye open and rinse slowly and gently wi th water for 15 - 20

minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing.  Call a poison control center or doctor for treatment advice. **If on skin:**  Take off contaminated clothing.

 Rinse skin immediately with plenty of water for 15 - 20 minutes.  Call a poison control center or doctor for treatment advice.

**HOT LINE NUMBER** Have the product container or label with you when calling a poison control center or doctor, or going for treatment. You may also contact the National Poison Control Hotline at 1 - 800 - 222 - 1222 for emergency medical treatment information.Master Label

Page 9 of 10 Dec. 4 , 201 2 **Use Restrictions** For use only on pome and stone fruit trees in residential settings. Not for use on trees or fruit grown for sale or other commercial use. **MIXING AN**  **D AP**  **PLICATION INSTRUCTIONS**  MADEX Twin must be mixe d with water and applied as a spray to the fruit and foliage of pome and stone fruit trees ( a pple, quince, pear, peach, nectarine, apricot, plum, cherry, walnut, and almond )

. Mix 1/2 teaspoon of MADEX Twin per 5 gallons of water and apply directly to eac h tree using a hand pump sprayer or other suitable spray equipment. Spray a sufficient volume to thoroughly wet all leaves and fruit with minimal run -off or dripping. Apply MADEX Twin first in late spring or early summer, when eggs of the first generatio n of codling moth or Oriental fruit moth begin to hatch. Apply MADEX Twin at least twice during each larval generation. Wh en pest pressure persists, make additional applications of MADEX Twin in mid - to late summer. Consult your local Cooperative Extension Service for more information about the best timing of codling moth and Oriental fruit moth sprays. MADEX Twin breaks down under direct exposure to - sunlight. If moths are still flying and laying eggs, reapply after 6 - 8 sunny days (counting 2 partially sun ny days as 1 sunny day). **STORA GE A** **ND DISPOSA L** 

Do not contaminate water, food, or feed by storage and disposal. **PESTICIDE STORA**

**GE:** Keep in original container. Store away from direct sunlight, feed, or foodstuffs. Keep container tightly sealed when not in u se. Store at temperatures below 41 ° F (5 ° C) . Bioactivity may be impaired by storage above 86°F (30 ° C) . Storing the product under cold or freezing temperature s will extend its shelf life. **PESTICIDE DISPOSA L A** **ND CONTA INER HA** **NDLING:** Non - refillable container. D o not reuse or refill container. **If empty :**  Place in trash or offer for recycling, if available. **If partly filled:**  Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.Master Label

Page 10 of 10 Dec. 4 , 201 2 **WA RRA** **NTY** Anderm att Biocontrol AG warrants that the material contained herein conforms to the description on the label and is reasonably fit for the purposes referred to in the directions for use. Timing and method of application, weather, watering practices, nature of so il, the insect problem, condition of the crop, incompatibility with other chemicals not specifically recommended and other influencing factors in the use of this product are beyond the control of the seller. To the extent consistent with applicable law, b u yer assumes all risks of use, storage or handling of this material not in strict accordance with directions given herein. To the extent consistent with applicable law, NO OTHER EXPRESS OR IMPLIED WARRANTY OF THE FITNESS OR MERCHANTABILITY IS MADE.