### Cover Letter

{XXX} Thank you for your assistance. We trust that you will find this information useful. If you have any questions, please don't hesitate to contact me. Sinecerely, Yvon Durant, PhD Chief Technology Officer Itaconix Corporation Direct: 1-603-686-7548 Fax: 1-603-617-4581 yvon.durant@itaconix.com

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Page 3 SANITIZED SUBMISSIONYvon Durant Chief Technology Officer ITACONIX CORP 2 Marin Way Stratham NH 03885 yvon.durant@itaconix.com Yvon Durant Chief Technology Officer Itaconix 2 Marin Way Stratham NH 03885 yvon.durant@itaconix.com 603-686-7548

Yvon Durant Chief Technology Officer Itaconix 2 Marin Way Stratham NH 03885 yvon.durant@itaconix.com 603-686-7548 

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Polyitaconic acid 

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Polyitaconic acid, potassium salt 

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Polyitaconic acid, ammonium salt 

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Polyitaconic acid, sodium zinc salt 

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Polyitaconic acid, partially decarboxylated 

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Page 57 SANITIZED SUBMISSION001 Sanitized Cover Letter Cover letter Sanitized 5 Consolidated PMNs Jan 2 002 Sanitized Structure DSP Acid Sanitized-poly(itaconic acid).docx Pt.I, Sec.B, 2e. 1 003 Sanitized CAS Report DSP Acid PMN Sanitized file of CAS Inventory Expert Report DSP Pt.I, Sec.B, 2c. 1 004 Sanitized MSDS DSP Acid PMN Sanitized file MSDS DSP Acid.pdf 2 005 Sanitized Process Diagram DSP Acid PMN Sanitized file Process Diagram DSP Acid.pdf Pt.2, Sec.A, 1d. 1 006 Sanitized GPC Chromatograph PMN Sanitized file of GPC Chromatograph.pdf 1 007 Sanitized GPC Slice Data PMN Sanitized file of GPC Slice Tbl.doc 15 008 Sanitized Oral and Dermal Toxicity PMN Sanitized file of Oral and Dermal Toxicity.pdf 11 009 Sanitized Ocular Tissue Study PMN Sanitized file of Ocular tissue study.pdf 7 010 Sanitized Sel cap without Calcium PMN Sanitized file Selenastrum capricornutum 96-hour growth 10 011 Sanitized Sel cap with Calcium PMN Sanitized file Selenastrum capricornutum 96-hour growth 12 012 Sanitized Daphnia magna 48-hour Acute Toxicity PMN Sanitized file Daphnia 15 013 Sanitized Inherant Biodegradability Study PMN Sanitized file OECD301A Inherent Biodegradability 7 014 Sanitized Structure DSP Potassium Sanitized-poly(potassium itaconate).docx Pt.I, Sec.B, 2e. (Chem 2) 1 015 Sanitized Structure DSP Ammonium Sanitized-poly(ammonium Pt.I, Sec.B, 2e. (Chem 3) 1 016 Sanitized Structure Itaconix Zinador Sanitized-poly(sodium zinc itaconate).docx Pt.I, Sec.B, 2e. (Chem 4) 1 017 Sanitized Structure Itaconix XDP Sanitized-poly(sodium itaconate co butenoate).docx Pt.I, Sec.B, 2e. (Chem 5) 1 018 Sanitized Process Diagram DSP Potassium PMN Sanitized file Process Diagram DSP Potassium.pdf Pt.2, Sec.A, 1d. (#2) 1 019 Sanitized Process Diagram DSP Ammonium PMN Sanitized file Process Pt.2, Sec.A, 1d. (#3) 1 020 Sanitized Process Diagram Itaconix Zinador PMN Sanitized file Process Diagram Itaconix Zinador.pdf Pt.2, Sec.A, 1d. (#4) 1 021 Sanitized Process Diagram Itaconix XDP PMN Sanitized file Process Pt.2, Sec.A, 1d. (#5) 1 

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022 Sanitized CAS Report DSP Potassium PMN Sanitized file of CAS Inventory Expert Report DSP Pt.I, Sec.B, 2c. (Chem 2) 1 023 Sanitized CAS Report DSP Ammonium PMN Sanitized file of CAS Inventory Expert Report DSP Pt.I, Sec.B, 2c. (Chem 3) 1 024 Sanitized CAS Report Itaconix Zinador PMN Sanitized file of CAS Inventory Expert Report Itaconix Pt.I, Sec.B, 2c. (Chem 4) 1 025 Sanitized CAS Report Itaconix XDP PMN Sanitized file of CAS Inventory Expert Report Itaconix Pt.I, Sec.B, 2c. (Chem 5) 1 026 Sanitized MSDS DSP Potassium PMN Sanitized file MSDS DSP Potassium.pdf 2 027 Sanitized MSDS DSP Ammonium PMN Sanitized file MSDS DSP Ammonium.pdf 2 028 Sanitized MSDS Itaconix Zinador PMN Sanitized file MSDS Itaconix Zinador.pdf 2 029 Sanitized MSDS Itaconix XDP PMN Sanitized file MSDS Itaconix XDP.pdf 2

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### ATTACHMENT HEADER SHEET Attachment Number 001 Attachment Name Sanitized Cover Letter 

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035

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### Report Number 2015150403092392035