Exhibit
      31.1




**Certification
        Pursuant to Section 13a-14 of the Securities Exchange Act of 1934
        of**
 **Thomas
        L. Wegman**
 **(President,
        Principal Executive Officer and Principal Financial
        Officer)**
  
 I,
          Thomas
          L. Wegman, certify that:
  1.
                I
                    have reviewed this Form 10-QSB for the quarterly period ended
                    June 30,
                    2006(the
                    “report”) of BioSpecifics Technologies Corp.
                    (“registrant”);
 
 2.
                Based
                    on my knowledge, the report does not contain any untrue statement
                    of a
                    material fact or omit to state a material fact necessary to make
                    the
                    statements made, in light of the circumstances under which such
                    statements
                    were made, not misleading with respect to the period covered
                    by this
                    report;
 
 3.
                Based
                    on my knowledge, the financial statements, and other financial
                    information
                    included in this report, fairly present in all material respects
                    the
                    financial condition, results of operations and cash flows of
                    the
                    registrant as of, and for, the periods presented in this
                    report;
 
 4.
                The
                    small business issuer’s other certifying officers and I are responsible
                    for establishing and maintaining disclosure controls and procedures
                    (as
                    defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal
                    control over financial reporting (as defined in Exchange Act
                    Rules
                    13a-15(f) and 15d-15(f)) for the small business issuer and
                    have:
  (a)         Designed
            such disclosure controls and procedures, or caused such disclosure controls
            and
            procedures to be designed under our supervision, to ensure that material
            information relating to the registrant, including its consolidated subsidiaries,
            is made known to us by others within those entities, particularly during
            the
            period in which this report is being prepared;
 
 (b)         Designed
            such internal control over financial reporting, or caused such internal
            control
            over financial reporting to be designed under our supervision, to provide
            reasonable assurance regarding the reliability of financial reporting
            and the
            preparation of financial statements for external purposes in accordance
            with
            generally accepted accounting principles;
 (c)         Evaluated
          the effectiveness of the registrant’s disclosure controls and procedures and
          presented in this report our conclusions about the effectiveness of the
          disclosure controls and procedures, as of the end of the period covered
          by this
          report based on such evaluation; and
  (d)         Disclosed
          in this report any change in the registrant’s internal control over financial
          reporting that occurred during the registrant’s most recent fiscal quarter (the
          registrant’s fourth fiscal quarter in the case of an annual report) that has
          materially affected, or is reasonably likely to materially affect, the
          registrant’s internal control over financial reporting; and
  5.
                The
                    small business issuer’s other certifying officers and I have disclosed,
                    based on our most recent evaluation of internal control over
                    financial reporting, to the registrant’s auditors and to the audit
                    committee of the registrant’s board of directors (or persons performing
                    the equivalent functions):
  (a)         All
          significant deficiencies and material weaknesses in the design or operation
          of
          internal controls over financial reporting which are reasonably likely
          to
          adversely affect the registrant’s ability to record, process, summarize and
          report financial information; and
 
 (b)         Any
          fraud, whether or not material, that involves management or other employees
          who
          have a significant role in the registrant’s internal controls over financial
          reporting.
  
 Date:  
          June 1, 2007
   /s/
          Thomas L. Wegman
 Thomas
          L.
          Wegman
 President
 (Principal
          Executive Officer and Principal Financial Officer)