UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20460 

## FEB Jl201Z

MEMORANDUM OFFICE OF CHEMICAL SAFETY AND POU.UTION PREVENTION

SUBJECT: BEAD Chemical Profile for Registration Review: DEET (080301) 

### FROM:



### THRU: David Brassard, Senior Entomologist Biological Analysis Branch / CynthiaDoucoure, Environmental Protection Specialist**.** 'l...fol:..wo.c:o-- Science Information and Analysis Branch Andrew Lee, Economist

# ~~- Economic Analysis Branch Biological and Economic Analysis Divisi (7503P) AmetJones, Chief

# ~**~ \l»ff~~**  Biological Analysis Branch

## ~/Aj Diann Sims, Chief

## J/Jtu,"'#"'---t::...a-~"Y"-- Science

### lnformation~Analysis Br ch Timothy Kiely, Chief 

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....**~** EconomicAnalysis Branch \.:\.)
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# lM.. Biological and EconomicAnalyslS Division 03P) 

### TO: Susan Bartow, Chemical Review Manager4 Risk Management and ImplementationBranch PesticideRe-evaluation Division (7508P)


### ProductReview Panel

### date: February22, 2012 INTRODUCTION Thepurpose ofthis document is to conveyusage information and a broad overview ofthe pest managementroles ofpesticides that arebeginning to undergo registration review. The anticipated audience consists ofthe team ofEPA staffcurrently evaluatingthe registration status ofDEET, and eventually the general public. This documentbuilds uponthe data already provided inthe "Usage andLabel Use DataPackages" that are also providedto RegistrationReview teams by BEAD. The document is based on information and data available to BEAD as of February 16, 2012. DEET (N,N-diethyl-meta-toluamide) is a broad spectrum insect and tick repellent used onthe human body and clothing and horses. DEET is used to repel biting flies, biting midges, black flies, chiggers, deer flies, fleas, gnats, horse flies, mosquitoes, no-see-urns, sand flies, stable flies, and ticks. DEET was registered in the United States in 1957 for use by the general public after first being developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas (EPA, 1998).
USE SITES Agricultural Use Sites DEET is notregistered for any agricultural uses. Non-Agricultural Use Sites DEET is registered for use onthe following sites: horses (animal treatment); and human skin, hair, clothing, footwear, shoes, and headgear (caps).
COMMON FORMULATIONS AND APPLICATION METHODS DEET is formulated as microencapsulated, pressurized spray (aerosol), impregnated materials (e.g. towelettes, roll-on), and ready-to-use solution (non aerosol pump sprays, liquids, creams, lotions. orfoams). DEET product concentrations range from 4% a.i. to 100% a.i. DEET is typically applied directly to clothing, hair, or human skin using aerosol sprays, non-aerosol sprays, creams, lotions, roll-ons, foams, and towelettes. Several DEET Products are also formulated with sunscreen. USAGE Non-Agricultural Available data on DEET show that it accounted for the overwhelming majority ofinsect repellents used in the U.S. in 2005, 2009, and 2012 according to private market research surveys (Table 1.) About 30% ofthe U.S. population uses DEET annually as an insect repellent (EPA, 1998). T bl 1 DEETU

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### 2009 2011 Million lb Million lb Million lb DEET 7.7 6.8 9.2 Source: Kline & Company, 2006,2010, and 2012 Page 2 of3BIOLOGICAL ASPECTS RELEVANT TO DEET The use ofeffective insect repellents such as DEETprovides certain public health benefits. Application ofDEET insect repellents to the skin and clothing can help prevent bites from mosquitoes, ticks and other biting insects that may vector diseases such as Lyme disease, West Nile virus, malaria, yellow fever, dengue fever, and encephalitis. HISTORY OF BEAD ASSESSMENTS FORDEET No BEAD assessments on DEET have been conducted. INFORMATION THAT MAY BE USEFUL FORBEAD'S FUTURE WORK ON DEET Obtaining additional information on current usage data for DEET in terms ofpounds a.i. applied and use rates would improve future BEAD assessments ofthe importance ofDEET and may be required as part ofthe registration review ofthis pesticide.
REFERENCES U.S. EPA. 1998. EPA Reregistration Eligibility Decision (RED). United States Environmental Protection Agency, Washington DC 20460. http://www.epa.gov/oppsrrdl/REDs/0002red.pdf Kline & Co., 2006, 2010, 2012

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