UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20460 

### APR 30 

### 2014

MEMORANDUM OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION

SUBJECT: BEAD Chemical Profile (BCP) for Registration Review: 4-CPA ( 4- cholorophenoxy-acetic acid) and Salts (019401 ) FROM:

THRU: Sunil Ratnayake, Biologist /\
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# h**~** Biological Analysis Branch \__ V 'fl '\h \ 

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# .**~** Sepehr Haddad, Environmental Protection Specialist 

# lj ___.;**/~** Science Information and Analysis Branch Derek Berwald, Economist

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# llj**~f0Q** Economic Analysis Branch Biological and Economic Analysis Divisio' 7503P) '

Diann Sims, Chief

### ~**vL.L.IInN~** Science Information and Analysis Branch Timothy Kiely, Chief 

# 0:**~** Economic Analysis Branch

## ~ Biological and Economic An is Division ( ) TO: Molly Clayton, Chemical Review Manager Risk Management and Implementation Branch I Pesticide Re-evaluation Division (7508P)
Peer Review Panel date: April3, 2014

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### SUMMARY 4-CPA (4-cholorophenoxy-acetic acid and salts) was first registered as a pesticide inthe U.S. in 1969 for use as a plant growth regulator for mung beans. 4-CP A is used inthe food industry to inhibit root growth during the seed germination ofmung beans. 

### INTRODUCTION The Biological and Economic Analysis Division (BEAD) Chemical Profile (BCP) provides an overview ofthe pest managementroles and quantitative usage information for 4-CPA and salts. The BCP includes summaries ofprevious BEAD products and available public and/or private use and usage data for 4-CP A and salts. Additional information on use is available inthe 4-CPA and salts LUIS Label Data Report. Information provided in this BCP may be used by stakeholders (e.g., users and registrants), OPP risk assessors, OPP risk managers, and the general public during the Registration Review process ofthis pesticide. 

### USE SITES Use Sites 4-CP A is used inthe food industry as a plant growth regulator to restrict root growth during seed germination ofmung beans. 

### FORMULATIONS AND APPLICATION METHODS 4-CPA is formulated in end-use products as a dry amorphous powder that is mixed with water. Itis applied by direct pour or by closed delivery systems. Use practice limitations prohibit the feeding ofbeanparts or hulls treated with 4-CPA to livestock. Contamination ofwater, food, or feed bythe storage or disposal of4-CPA also is prohibited. 

### HISTORY OF 4-CPA AND BEAD PRODUCTS There are no records ofrelevant BEAD assessments for 4-CPA and salts. A Reregistration Eligibility Decision (RED) was issued inMarch 1997 (USEPA, 1997) for this chemical. 

### USAGE Agricultural Usage There is no available usage data onmung bean use from any ofour public or proprietary databases. The Pesticide Re-evaluation Division (PRD) contacted the registrant inFebruary 2014 to inquire about formulation and usage ofthis chemical and they responded that the material is a dry amorphous powder that is mixed (12grams) into 1 liter ofwater to dissolve and then added to a mixture of3500 lbs. ofmung beans and approximately 1150 gallons ofwater. According Page2to the registrant ofthis chemical, I0 to 20 lbs. of4-CPA are used in a year depending on the demand ofmung bean sprouts needed in that year (Allomong, R., ConAgra Foods. Personal Communication. Feb. 04, 2014). The use of4-CPA was described in the 1997 Reregistration Eligibility Decision (R.E.D.): 4-CPA is used in the food industry as a plant growth regulator to restrict root growth during seed germination ofmung beans. 4-CPA is applied to the water bath to soak the beans. Once the beans have soaked for several hours, they are washed to remove the surface residues, and are then germinated indoors for several days. After sprouting, the hulls and roots are discarded, and the remaining portion is packaged and sold for human consumption (USEPA, 1997). Non-Agricultural Usage There are no non-agricultural uses for 4-CPA. BIOLOGICAL ASPECTS RELEVANT TO 4-CPA AND SALTS One ofthe auxin type plant growth hormone regulating the cell division is 4-CPA. Currently 4- CPA is used as a plant growth regulator for restricting root growth ofmung beans in food industry (USEPA, 1997). It is not used as a pesticide to control any pest in crop production fields in the United States. ROLE OF 4-CPA AND SALTS IN FOOD PROCESSING 4-CPA plays a role in food industry and it is used as a plant growth regulator to restrict the root growth ofmung bean sprouts during the germination ofseeds. DATA NEEDS BEAD has the necessary usage data on 4-CPA and salts.
REFERENCES USEPA. 1997. Reregistration EligibilityDecision (RED): 4-Chlorophenoxy-acetic Acid (4-CPA). Available online: http://www.epa.gov/oppsrrd1 /REDs/2115red.pdf
. Retrieved on March 11, 2014.

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