Exhbit 10.22

AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT

| | THIS
AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT is made and entered into as of May 1, 2004, by
and between Immucor, Inc., a Georgia corporation with its executive offices at 3130
Gateway Drive, Norcross, Georgia 30071 (herein referred to as Employer or the
Company), and Gioacchino De Chirico, residing at 1992 Winchelsea Court,
Dunwoody, Georgia 30338 (herein referred to as Employee), and amends the
Employment Agreement between the Company and Employee dated December 1, 2003 (the Original
Agreement).
| | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | The
purpose of this Amendment is to reflect that as of April 30, 2004, Employee was promoted
to Chief Executive Officer of the Company while continuing to serve as the President of
the Company, and Employees base compensation was increased in connection with that
promotion. The parties therefore agree as follows.
| | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | 1. | Section
1 of the Original Agreement is hereby amended in its entirety to read as
          follows:
| | -- | ---------------------------------------------------------------------------------------------------

| | Employer
hereby employs Employee as Chief Executive Officer and President of Employer to perform
the services and duties normally and customarily associated with Employees
position, such duties as specified in the Employers bylaws, and such other duties
as may from time to time be specified by the Employers Board of Directors. Employee
will be retained in this position during the term of his employment under this Employment
Agreement, and hereby agrees to perform such services and duties in this capacity.
| | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | 2. | Schedule
A is hereby amended to read as attached hereto, to reflect  Employees
increased base compensation.
| | -- | ------------------------------------------------------------------------------------------------------------

| | The
parties have executed and delivered this Amendment as of the date first mentioned above.
| | --------------------------------------------------------------------------------------------

| |                                                
| | -----------------------------------------------
| | IMMUCOR, INC.                                  
| |                                                
| |                                                
| | By:     _______________________________________
| | Edward L. Gallup, Chairman                     

---

# SCHEDULE A

EMPLOYMENT  AGREEMENT  DATED
DECEMDER 1, 2003 BY AND BETWEEN  IMMUCOR,  INC. AND GIOACCHINO DE CHIRICO,  AS AMENDED
EFFECTIVE MAY 1, 2004.

The following compensation and
benefits are effective as of May 1, 2004:

| | Base
compensation: $375,000.00 a year payable in 26 installments every two weeks.
| | ---------------------------------------------------------------------------------

| | Outplacement
Assistance Benefit: $30,000.00.
| | --------------------------------------------

| | Automobile
Allowance: $9,600.00 a year payable in 12 monthly installments.
| | --------------------------------------------------------------------------

| |                                                
| | -----------------------------------------------
| | IMMUCOR, INC.                                  
| |                                                
| |                                                
| | By:     _______________________________________
| | Edward L. Gallup, Chairman                     

(This Schedule A supersedes and
replaces any Schedule A previously executed by the parties hereto.)