Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate

PC Code: 034903, 076413, 176407

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

MEMORANDUM

SUBJECT: Product Chemistry Scoping Document for the Registration Review o

Monopotassium Phosphate, 

Registration Review Case #: 

PC Code:

CAS Numbers:

Chemical Class:

FROM: Angela L. Gonzales, Biologist

Biochemical Pesticides Branch

Biopesticides & Pollution Prevention Division (7511P)

TO: Leonard Cole, Senior Regulatory Specialist

Biochemical Pesticides Branch

Biopesticides & Pollution Prevention Division (7511P) 

ACTION REQUESTED

The following scoping document contains the product chemistry assessmen

phosphate, monopotassium phosphate and 

Registration Review Work Plan.

Executive Summary

The Agency has made the determination that 

product chemistry information available on

phosphate. While the information on file is adequate 

applications, more data and/or information for certain data requirements for these chemicals should be 

submitted. The data requirements that should be further addressed are discussed below for each 

chemical. 

Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case

Product Chemistry

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460

September 6, 2012

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION

Product Chemistry Scoping Document for the Registration Review of Ferric

Monopotassium Phosphate, and Dipotassium Phosphate. 

 6072

034903, 076413, 176407

100045-86-0, 7778-77-0, 7758

Biochemical

Biologist 

Biochemical Pesticides Branch

Biopesticides & Pollution Prevention Division (7511P)

Leonard Cole, Senior Regulatory Specialist

Biochemical Pesticides Branch

Biopesticides & Pollution Prevention Division (7511P) 

The following scoping document contains the product chemistry assessment for the biopestici

, monopotassium phosphate and dipotassium phosphate in support of the development of the 

has made the determination that for the purposes of registration review, there is adequate

information available on ferric phosphate, monopotassium phosphate and dipotassium 

While the information on file is adequate for registration review, for future pesticide 

applications, more data and/or information for certain data requirements for these chemicals should be 

. The data requirements that should be further addressed are discussed below for each 

Case #: 6072

Product Chemistry—Registration Review

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION

Ferric Phosphate, 

7758-11-4

t for the biopesticides ferric 

in support of the development of the 

there is adequate

ferric phosphate, monopotassium phosphate and dipotassium 

review, for future pesticide 

applications, more data and/or information for certain data requirements for these chemicals should be 

. The data requirements that should be further addressed are discussed below for each 
Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case #: 6072

PC Code: 034903, 076413, 176407 Product Chemistry—Registration Review

Introduction

Ferric Phosphate

As a pesticide, ferric phosphate is used as a molluscicide (specifically, slugs and snails) on and around a variety 

of ornamental and food crops. The active ingredient was first registered in 1997. There are currently two 

products registered containing the active ingredient, all of which are end-use products (EPs). One product 

contains ferric phosphate as the only active ingredient and the other product contains the biopesticide in 

conjunction with a conventional chemical (spinosad). The chemical is not approved for use as an inert 

ingredient in pesticide formulations at this time.

Monopotassium Phosphate

As a pesticide, monopotassium phosphate is used as a fungicide on a variety of ornamental and food crops. The 

active ingredient was first registered in 1994. There are currently four products registered containing the active 

ingredient, all of which are EPs. Two of the products contain the active ingredient in conjunction with a 

conventional chemical (sulfur), one product contains the active ingredient in conjunction with another 

biopesticide (mono- and di- potassium salts of phosphorous acid) and the last product contains monopotassium 

phosphate as the only active ingredient. The chemical is approved for use as an inert ingredient in pesticide 

formulations for both nonfood and food (40 CFR § 180.910 and 180.920) uses.

Dipotassium Phosphate

As a pesticide, dipotassium phosphate is used as a fungicide on a variety of ornamental and food crops. The 

active ingredient was first registered in 2002. There is currently one product registered containing the active 

ingredient; an EP which contains the chemical in conjunction with another biopesticide (mono- and dipotassium salts of phosphorous acid). The chemical is approved for use as an inert ingredient in pesticide 

formulations for both nonfood and food (40 CFR § 180.920) uses.

Product Chemistry Summary

Ferric Phosphate

Concerning the product chemistry of ferric phosphate, most biochemical pesticide data requirements for 

the technical grade active ingredient have been satisfied and are summarized in Table 1 and Table 2. 

While the information on file is adequate for the purposes of registration review, for future pesticide 

applications, data on the partition coefficient of the chemical must be submitted according to OCSPP 

Guidelines 830.7550-7570 and more specific data on the stability of the chemical should be submitted 

according to OCSPP Guideline 830.6313. 
Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case #: 6072

PC Code: 034903, 076413, 176407 Product Chemistry—Registration Review

3

Table 1. Product Identity and Composition for Ferric Phosphate

Common Name Iron (III) phosphate; ferric phosphate; ferric 

orthophosphate

Chemical Name, IUPAC Phosphoric acid, iron 3+

salt (1:1)

Molecular Weight 150.82

PC Code 034903

CAS Registry Number 10045-86-0

Molecular Formula FeO4P

Registration Review Case Number 6072

Chemical Structure

The Agency has conducted a review of the available product chemistry data and information. These data are 

summarized below.

Table 2. Biochemical Pesticides Product Chemistry Data Requirements for Ferric Phosphate

Guideline 

No.

Physical and Chemical 

Properties

Status1 Value MRID

830.1100 Product Identity and 

Composition

A Refer to Table 1. 44073401

44732201

830.1200 Description of starting 

materials, production and 

formulation process

A Confidential Business 

Information (CBI)

44073401

44732201

830.1400 Discussion of formation of 

impurities

A CBI 44732201

830.1700 Preliminary analysis A CBI 44042701

44131901

46811902
Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case #: 6072

PC Code: 034903, 076413, 176407 Product Chemistry—Registration Review

4

830.1800 Enforcement analytical 

method

A CBI 44042701

44131901

44732202

46811902

48741601

830.6302 Color A White to buff 44042703

830.6303 Physical state A Dry powder 44042703

830.6304 Odor A Odorless 44042703

830.6313 Stability to normal and 

elevated temperatures, metals 

and metal ions

A Stable.

More specific data should 

be provided to support 

future registrations (refer 

to OCSPP Guideline 

830.6313).

44042703

830.7000 pH N/A Not applicable; chemical is 

not soluble in water.

44042703

830.7050 UV/Visible light absorption N/A Data are not necessary to 

inform the risk assessment.

830.7200 Melting point/melting range N/D Does not melt; degrades into 

ferric oxide at temperatures

near 500oC

44042703

830.7220 Boiling point/boiling range N/A Not applicable; chemical is 

not a liquid at room 

temperature

830.7300 Density A 1 g/ml or 60 lb/ft3

(bulk 

density)

44042703

830.7520 Particle size, fiber length, and 

diameter distribution

A 3 microns (per MSDS) 44070601

830.7550

830.7560

830.7570

Partition coefficient (nOctanol/Water)N/A Not applicable; chemical is 

an organic compound

830.7840 Water solubility A Insoluble in water 44042703

830.7950 Vapor pressure N/A Not applicable; chemical is a 

non-volatile solid

44042703

1 A=Acceptable. N/A=Not Applicable. N/D=Not Determined.

Monopotassium Phosphate
Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case #: 6072

PC Code: 034903, 076413, 176407 Product Chemistry—Registration Review

5

Concerning the product chemistry of monopotassium phosphate, most biochemical pesticide data 

requirements for the technical grade active ingredient have been satisfied and are summarized in Table 3 

and Table 4. While the information on file is adequate for the purposes of registration review, for future 

pesticide applications, more specific data on the stability of the chemical should be submitted according 

to OCSPP Guideline 830.6313. 

Table 3. Product Identity and Composition for Monopotassium Phosphate

Common Name Monopotassium phosphate; phosphoric acid, 

monopotassium salt; potassium phosphate, monobasic

Chemical Name, IUPAC Potassium dihydrogen phosphate

Molecular Weight 136.09

PC Code 076413

CAS Registry Number 7778-77-0

Molecular Formula H2KO4P

Registration Review Case Number 6072

Chemical Structure

The Agency has conducted a review of the available product chemistry data and information. These data are 

summarized below.

Table 4. Biochemical Pesticides Product Chemistry Data Requirements for Monopotassium Phosphate

Guideline Physical and Chemical Status1 Value MRID
Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case #: 6072

PC Code: 034903, 076413, 176407 Product Chemistry—Registration Review

6

No. Properties

830.1100 Product Identity and 

Composition

A Refer to Table 3. 44234201

830.1200 Description of starting 

materials, production and 

formulation process

A CBI 44234201

830.1400 Discussion of formation of 

impurities

A CBI 44234201

830.1700 Preliminary analysis A CBI 44234201

830.1800 Enforcement analytical 

method

A CBI

830.6302 Color A White 44234201

830.6303 Physical state A Crystalline solid 44234201

830.6304 Odor A No characteristic odor 44234201

830.6313 Stability to normal and 

elevated temperatures, metals 

and metal ions

A Stable 

More specific data should 

be provided to support 

future registrations (refer 

to OCSPP Guideline 

830.6313).

44234201

830.7000 pH A 4.5 (1% solution) 44234201

830.7050 UV/Visible light absorption N/A Data are not necessary to 

inform the risk assessment.

830.7200 Melting point/melting range A 253oC HSDB2

830.7220 Boiling point/boiling range N/A Not applicable; chemical is 

not a solid at room 

temperature

830.7300 Density A 1.3 g/cm3

2.3 g/cm3

44234201

HSDB2

830.7520 Particle size, fiber length, and 

diameter distribution

N/A Not applicable; chemical is 

not water insoluble and 

fibrous with a diameter ≥ 

0.1μm

830.7550

830.7560

830.7570

Partition coefficient (nOctanol/Water)N/A Not applicable; data are not 

required for chemicals that 

are soluble in water.

830.7840 Water solubility A Soluble

25g/100ml water

44234201

HSDB2
Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case #: 6072

PC Code: 034903, 076413, 176407 Product Chemistry—Registration Review

7

830.7950 Vapor pressure N/A Not applicable; chemical is a 

non-volatile solid

1A=Acceptable. N/A=Not Applicable. N/D=Not Determined.

2Hazardous Substances Data Bank, 2012.

Dipotassium Phosphate

Concerning the product chemistry of dipotassium phosphate, most biochemical pesticide data 

requirements for the technical grade active ingredient have been satisfied and are summarized in Table 5 

and Table 6. While the information on file is adequate for the purposes of registration review, for future 

pesticide applications, more specific data on the stability of the chemical should be submitted according 

to OCSPP Guideline 830.6313 and more specific data on the solubility of the chemical should be 

submitted according to OCSPP Guideline 830.7840. 

Table 5. Product Identity and Composition for Dipotassium Phosphate

Common Name Dipotassium phosphate; phosphonic acid, dipotassium 

salt; potassium phosphate, dibasic

Chemical Name, IUPAC dipotassium monohydrogen phosphate

Molecular Weight 174.18

PC Code 176407

CAS Registry Number 7758-11-4

Molecular Formula HK2O4P

Registration Review Case Number 6072

Chemical Structure
Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case #: 6072

PC Code: 034903, 076413, 176407 Product Chemistry—Registration Review

8

The Agency has conducted a review of the available product chemistry data and information. These data are 

summarized below.

Table 6. Biochemical Pesticides Product Chemistry Data Requirements for Dipotassium Phosphate

Guideline 

No.

Physical and Chemical 

Properties

Status1 Value MRID

830.1100 Product Identity and 

Composition

A Refer to Table 1. 44815001

830.1200 Description of starting 

materials, production and 

formulation process

A CBI 44815001

830.1400 Discussion of formation of 

impurities

A CBI 44815001

830.1700 Preliminary analysis A CBI 44815001

830.1800 Enforcement analytical 

method

A CBI 44815004

830.6302 Color A White Merck 

Index2

830.6303 Physical state A Granules/crystals Merck 

Index2

830.6304 Odor N/D No characteristic odor MSDS4

830.6313 Stability to normal and 

elevated temperatures, metals 

and metal ions

A Stable

More specific data should 

be provided to support 

future registrations (refer 

to OCSPP Guideline 

830.6313).

MSDS4

830.7000 pH A 8.8 (1% solution) HSDB3

830.7050 UV/Visible light absorption N/A Data are not necessary to 

inform the risk assessment

830.7200 Melting point/melting range A 340oC MSDS4

830.7220 Boiling point/boiling range A Not applicable; chemical is 

not a liquid at room 

temperature

830.7300 Density A 2.30 g/cm3 MSDS4

830.7520 Particle size, fiber length, and 

diameter distribution

N/A Not applicable; chemical is 

not water insoluble and 

fibrous with a diameter ≥ 

0.1μm
Ferric Phosphate, Monopotassium Phosphate, Dipotassium Phosphate Case #: 6072

PC Code: 034903, 076413, 176407 Product Chemistry—Registration Review

9

830.7550

830.7560

830.7570

Partition coefficient (nOctanol/Water)N/A Not applicable; data are not 

required for chemicals that 

are soluble in water.

830.7840 Water solubility A Soluble

More specific data should 

be provided to support 

future registrations (refer 

to OCSPP Guideline 

830.7840).

MSDS4

830.7950 Vapor pressure N/A Not applicable; chemical is a 

non-volatile solid.

1A=Acceptable. N/A=Not Applicable. N/D=Not Determined.

2

The Merck Index, 2012

3HSDB, 2012

4MSDS, 2012

References

Hazardous Substances Data Bank (HSDB). United States National Library of Medicine, Online. 09/04/12.

< http://www.toxnet.nlm.nih.gov/cgi-bin/sis/search>

Material Safety Data Sheet (MSDS) for Potassium Phosphate, Dibasic. Sigma-Aldrich. Online. 09/06/12.

< http://www.sigmaaldrich.com>

The Merck Index Online. 14th Edition. EPA Library Search. 09/05/12.

< http://library.dialog.com/bluesheets/html/bl0304.html>