EXHIBIT 10.21

# EMPLOYMENT AGREEMENT

|THIS
AGREEMENT, made and entered into as of this 1st day of December, 2003, by and between
Immucor, Inc., a Georgia corporation with its executive offices at 3130 Gateway Drive,
Norcross, Georgia 30071 (herein referred to as Employer or the Company),
and Gioacchino De Chirico, residing at 1992 Winchelsea Court, Dunwoody, Georgia 30338
(herein referred to as Employee).
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WITNESSETH

|WHEREAS,
the parties hereto desire to enter into an agreement for Employers employment of
Employee on the terms and conditions hereinafter states.
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|NOW,
THEREFORE, in consideration of the premises and the mutual covenants and agreements
herein contained, the parties hereby agree as follows:
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1.      Relationship
Established

| | Employer
hereby employs Employee as President and COO of Employer to perform the services and
duties normally and customarily associated with Employees position, such duties as
specified in the Employers bylaws, and such other duties as may from time to time
be specified by the Employers Board of Directors. Employee will be retained in this
position during the term of his employment under this Employment Agreement, and hereby
agrees to perform such services and duties in this capacity.
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2.      Extent
of Services

| | Employee
shall devote substantially all his business time, attention skill and efforts to the
performance of his duties hereunder, and shall use his best efforts to promote the
success of the Employers business.
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3.     Term of
Employment

| | Employees
employment hereunder shall commence on December 1, 2003 (hereinafter called the Effective
Date, and shall continue for a period of five (5) years, unless sooner terminated
by the first to occur of the following:
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| | (a) | The
death or complete disability of Employee. Complete disability,
                    as used herein, shall mean the inability of Employee, due to illness,
accident                     or any other physical or mental incapacity, to perform the
services provided for                     hereunder for an aggregate of 12 months during
the term hereof.
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---

| | (b) | The
discharge of Employee by Employer for Cause. Employees discharge shall
                    be for Cause if due to any of the following:
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| | (i) | Employees
dishonesty,
| | --- | ----------------------

| | (ii) | An
act of defalcation committed by Employee,
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| | (iii) | Employees
continuing inability or refusal to perform reasonable duties assigned to
him hereunder (unless such refusal occurs following the occurrence of a
Change of Control, as defined herein) or
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| | (iv) | Employees
moral turpitude.
| | ---- | ---------------------------

| | Disability
because of illness or accident or any other physical or mental disability shall not
constitute a basis for discharge for Cause.
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| | (c) | The
discharge of Employee by Employer without Cause (which shall be deemed to
                    have occurred if Employees employment hereunder terminates
under Section 7                     hereof).
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| | (d) | At
Employees request and with the express prior written consent of
                    Employer.
| | --- | -------------------------------------------------------------------------------------------------

| | (e) | At
Employees election upon 120 days notice (or such lesser notice as
                    Employer may accept), without the express prior written consent of
Employer.
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| | (f) | At
the end of the term of the Agreement, or any extension thereof, if  either
                    the Employer or Employee gives 60 days notice to the other of
non-renewal of the                     Agreement.
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| | If
not sooner terminated under the provisions of Sections 3(a) through 3(f) above, the term
of Employees employment hereunder shall automatically renew for an additional
period of five (5) years.
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4.     Compensation

| | (a) | Subject
to the provisions of Section 4(d), Employer will pay to Employee as base
                    compensation for the services to be performed by him hereunder the
base                     compensation specified on Schedule A attached hereto. Schedule A
may be amended                     from time to time upon the parties revision and
re-execution thereof,                     whereupon the amended Schedule A shall be
attached hereto; provided, however,                     the amended Schedule A shall be
effective upon such re-execution, whether or not                     it is attached
hereto.
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| | (b) | The
Employee may be entitled to additional bonus compensation as may be
                    determined by the Board of Directors of Employer from time to time,
any such                     determination to be final, binding, conclusive on Employee
and all other                     persons.
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| | (c) | In
the event Employees employment shall terminate under Section 3(c)
                    hereof, the Employee shall be paid an amount equal to the Average
Annual                     Compensation payable to Employee under Schedule A for the
remainder of the term                     of this Agreement in accordance with the
payment schedule set forth on Schedule                     A, to be paid over the
remainder of the term of this Agreement following                     termination. For
purposes of this Section, Average Annual                     Compensation shall
mean the Employees annual base compensation                     payable to Employee
under Schedule A in accordance with the payment schedule set                     forth on
Schedule A together with his Average Bonus. Average Bonus                    shall
mean the average bonus paid to employee over the last two years in which
                    the Employee was eligible to receive a bonus or such lesser number of
years in                     which Employee was eligible to receive a bonus.
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---

| | (d) | In
the event Employees employment shall terminate under Section 3(a),
                    3(b), 3(d), 3(e) or 3(f) hereof, all of Employers obligations
to Employee                     hereunder will cease automatically and Employee shall
only be entitled to                     compensation accrued through the date of
termination.
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5.     Expenses

| | Employee
shall be entitled to receive reimbursement for, or payment directly by the Employer of,
all reasonable expenses incurred by Employee at the request of the Employer in the
performance of his duties under this Agreement, provided that Employee accounts therefor
in writing and that such expenses are ordinary and necessary business expenses of the
Employer within the meaning of Section 162 of the Internal Revenue Code of 1986 as
amended.
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6.     Insurance and Other
Fringe Benefits

| | Employer
will provide Employee with (a) health insurance, dental insurance, long-term disability
insurance, paid vacations and other fringe benefits in the form and in dollar amounts
substantially equivalent to the benefits provided to the Employers other employees
in a similar position and with similar responsibilities, and (b) life insurance for the
benefit of the Employee and/or the Employer, as provided on Schedule B attached hereto.
Schedule B may be amended from time to time upon the parties revision and
re-execution thereof, whereupon the amended Schedule B shall be attached hereto;
provided, however, the amended Schedule B shall be effective upon such re-execution,
whether or not it is attached hereto.
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7.     
          Termination of Employment Upon Sale or Change of Control of Employers
          Business; Severance

|(a) |  | Notwithstanding anything to the contrary contained in this Agreement, either
                    Employer or Employee may terminate Employees employment hereunder if any
                    of the following events occur:
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| | (i) | Sale
of Employers Assets. The sale of all or substantially all of           Employers
assets to a single purchaser or group of associated purchasers,           whether in a
single transaction or a series of related transactions.
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| | (ii) | Sale
of Employers Shares. The sale, exchange, or other disposition,           in one
transaction, or in a series of related transactions, of twenty percent           (20%) or
more of Employers outstanding shares of capital stock.
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| | (iii) | Merger
or Consolidation. The merger or consolidation of Employer in a           transaction
or series of transactions in which Employers shareholders           receive or
retain less than fifty percent (50%) of the outstanding voting shares           of the
new or surviving corporation.
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| | (iv) | Other
Changes in Control. The occurrence of any change in control of the           Employer
within the meaning of federal securities law.
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---

| | (b) | If,
within 60 days after an event described in Sections 7(a)(i), (a)(ii),
                    (a)(iii) or (a)(iv) (a Change of Control), the Employee
voluntarily                     terminates his employment with the Employer, or if within
two years after a                     Change of Control Employer terminates Employees
employment (whether for                     Cause or without Cause) the Employer
terminates Employees employment, then                     Employer shall pay
Employee (instead of the amount specified in Section 4(c), if                     any,
but together with the amount specified in Section 7(d), if any) an amount
                    equal to two times the Employees Average Annual Compensation
(as defined                     below), to be paid in a single payment at the time of
termination. In                     consideration of such payment and his employment
hereunder through the date of                     such termination, Employee agrees to
remain bound by the provisions of this                     agreement which specifically
relate to periods, activities or obligations upon                     or subsequent to
the termination of Employees employment.
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| | (c) | Upon
a Change of Control, Employees existing options under any Immucor
                    Inc. (the Company) option plan, including the Companys
1990                     Stock Option Plan, the Companys 1995 Stock Option Plan,
the Companys                     1998 Stock Option Plan, and the Companys
2003 Stock Option Plan, if any,                     shall immediately vest and become
exercisable in full and shall remain                     exercisable for the full term
stated in such option plan or in any stock option                     agreement between
the Company and the Employee.
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| | (d) | If,
within 60 days after a Change of Control, either the Employee voluntarily
                    terminates his employment with the Employer or the Employer
terminates                     Employees employment other than for Cause, then
Employer shall pay to                     Employee an outplacement assistance benefit for
the purpose of assisting                     Employee with counseling, travel and other
expenses related to finding new                     employment. Such amount shall be paid
in cash in the amount specified on                     Schedule A attached hereto.
Schedule A may be amended from time to time upon the                     parties revision
and re-execution thereof, whereupon the amended Schedule                     A shall be
attached hereto; provided, however, the amended Schedule A shall be
                    effective upon such re-execution, whether or not it is attached
hereto.
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| | (e) | For
purposes of this Section, Average Annual Compensation shall mean
                    the Employees annual base compensation payable to Employee
under Schedule                     A in accordance with the payment schedule set forth on
Schedule A together with                     his Average Bonus. Average Bonus shall
mean the average of the                     bonuses paid to Employee over the last two
years (or such lesser number of years                     in which Employee was eligible
to receive a bonus) in which the Employee was                     eligible to receive a
bonus.
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| | (f) | Certain
Additional Payments by Employer. In the event that                     Employee
becomes entitled to severance benefits or any other benefits or
                    payments in connection with this Agreement, whether pursuant to the
terms of                     this Agreement or otherwise (collectively, the Total
Benefits) and                     (ii) any of the Total Benefits will be subject to
the excise tax imposes                     pursuant to Section 4999 of the Internal
Revenue Code (Excise Tax),                     which tax may be imposed if
the payments made to Employee are deemed to be                     excess parachute
payments within the meaning of Section 280G of the                     Code, then
Employer shall pay to employee an additional amount (the                     Gross-Up
Payment) such that the net amount retained by Employee,                     after
deduction of any Excise Tax on the Total Benefits and any federal, state
                    and local income taxes, Excise Tax, and FICA and Medicare withholding
taxes upon                     the payment provided for by this Section, will be equal to
the Total Benefits so                     that Employee shall be, after payment of all
taxes, in the same financial                     position as if no taxes under Section
4999 had been imposed upon him. For                     purposes of this Section,
Employee will be deemed to pay federal income taxes at                     the highest
marginal rate of federal income taxation in the calendar year in
                    which the Excise tax is (or would be) payable and state and local
income taxes                     at the highest marginal rate of taxation in the state
and locality of                     Employees residence on the Date of Termination,
net of the reduction in                     federal income taxes that could be obtained
from the deduction of such state and                     local taxes (calculated by
assuming that any reduction under Section 68 of the                     Internal revenue
Code in the amount of itemized deductions allowable to Employee
                    applies first to reduce the amount of such state and local income
taxes that                     would otherwise be deductible by Employee).
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|8. | Employer
shall promptly reimburse Employee for any and all legal fees and                expenses
incurred by him as a result of a termination of employment described in
               Section 7(b), including without limitation all fees and expenses incurred
to                enforce the provisions of this Agreement.
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9.     
          Prohibited Practices.

| | During
the term of Employees employment hereunder, for a period of two years after such
employment is terminated for any reason, in consideration of the compensation being paid
to Employee hereunder, Employee shall:
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| | (a) | not
solicit business from anyone who is or becomes an active or prospective
                    customer of Employer or its affiliates and with whom the Employee had
dealt with                     or had material contact during his term of employment
under this Agreement.
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| | (b) | not
solicit for employment or hire any employee of Employer or its affiliates
                    that the Employee had contact with during his term of employment
under this                     Agreement.
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10.     
          Non-Disclosure.

| | a. | Protection
of Trade Secrets. Employee acknowledges that during the           course of his or
her employment, Employee will have significant access to, and           involvement with,
the Companys Trade Secrets and Confidential Information.           Employee agrees
to maintain in strict confidence and, except as necessary to           perform his or her
duties for the Company, Employee agrees not to use or           disclose any Trade
Secrets of the Company during or after his or her employment.           Employee agrees
that the provisions of this subsection shall be deemed           sufficient to protect
Trade Secrets of third parties provided to the Company           under an obligation of
secrecy. As provided by Georgia statutes, Trade           Secret shall mean
any information (including, but not limited to,           technical or non-technical
data, a formula, a pattern, a compilation, a program,           a device, a method, a
technique, a drawing, a process, financial data, financial           plans, product
plans, or a list of actual or potential customers) that: (i)           derives economic
value, actual or potential, from not being generally known to,           and not being
readily ascertainable by proper means by, other persons who can           obtain economic
value from its disclosure or use; and (ii) is the subject of           efforts that are
reasonable under the circumstances to maintain its secrecy.
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| | b. | Protection
of Other Confidential Information. In addition, Employee           agrees to maintain
in strict confidence and, except as necessary to perform his           or her duties for
the Company, not to use or disclose any Confidential           Information of the Company
during his or her employment and for a period of 12           months following
termination of Employees employment. Confidential           Information shall
mean any internal, non-public information (other than           Trade Secrets already
addressed above) concerning (without limitation) the           Companys financial
position and results of operations (including revenues,           assets, net income,
etc.); annual and long-range business plans; product or           service plans;
marketing plans and methods; training, educational and           administrative manuals;
supplier information and purchase histories; customers           or clients; personnel
and salary information; and employee lists. Employee           agrees that the provisions
of this subsection shall be deemed sufficient to           protect Confidential
Information of third parties provided to the Company under           an obligation of
secrecy.
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| | c. | Rights
to Work Product. Except as expressly provided in this Agreement,           the
Company alone shall be entitled to all benefits, profits and results arising
          from or incidental to Employees performance of his or her job duties to
          the Company. To the greatest extent possible, any work product, property, data,
          invention, know-how, documentation or information or materials
          prepared, conceived, discovered, developed or created by Employee in connection
          with performing his or her employment responsibilities during Employees
          employment with the Company shall be deemed to be work made for hire          as
defined in the Copyright Act, 17 U.S.C.A. § 101 et seq., as amended, and
          owned exclusively and perpetually by the Company. Employee hereby
          unconditionally and irrevocably transfers and assigns to the Company all
          intellectual property or other rights, title and interest Employee may
currently           have (or in the future may have) by operation of law or otherwise in
or to any           work product. Employee agrees to execute and deliver to the Company
any           transfers, assignments, documents or other instruments which the Company
may           deem necessary or appropriate to vest complete and perpetual title and
ownership           of any work product and all associated rights exclusively in the
Company. The           Company shall have the right to adapt, change, revise, delete
from, add to           and/or rearrange the work product or any part thereof written or
created by           Employee, and to combine the same with other works to any extent,
and to change           or substitute the title thereof, and in this connection Employee
hereby waives           the moral rights of authors as that term is commonly
understood           throughout the world including, without limitation, any similar
rights or           principles of law which Employee may now or later have by virtue of
the law of           any locality, state, nation, treaty, convention or other source.
Unless           otherwise specifically agreed, Employee shall not be entitled to any
additional           compensation, beyond his or her salary, for any exercise by the
Company of its           rights set forth in the preceding sentence.
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| | d. | Return
of Materials. Employee shall surrender to the Company,           promptly upon its
request and in any event upon termination of Employees           employment, all
media, documents, notebooks, computer programs, handbooks, data           files, models,
samples, price lists, drawings, customer lists, prospect data, or           other
material of any nature whatsoever (in tangible or electronic form) in the
          Employees possession or control, including all copies thereof, relating
to           the Company, its business, or its customers. Upon the request of the
Company,           employee shall certify in writing compliance with the foregoing
requirement.
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11.     
          Severability.

| | It
is the intention of the parties that if any of the restrictions or covenants contained
herein is held to cover a geographic area or to be for a length of time or to apply to
business activities which is not permitted by applicable law, or in any way construed to
be too broad or to any extent invalid, such provision shall not be construed to be null,
void and of no effect, but to the extent such provision would be valid or enforceable
under applicable law, a court of competent jurisdiction shall construe and interpret or
reform this Section to provide for a covenant having the maximum enforceable geographic
area, time period and any other provisions (not greater than those contained herein) as
shall be valid and as shall be valid and enforceable under such applicable law.
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| | If
any provision contained in this Section shall for any reason be held invalid, illegal or
unenforceable in any respect, such invalidity, illegality or unenforceability shall not
affect any other provisions of this Section, but this Section shall be construed as if
such invalid, illegal or unenforceable provision had never been contained herein.
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| | This
agreement supercedes any prior agreement between Employer and Employee.
| | ----------------------------------------------------------------------------

12.     Waiver of Provisions

| | Failure
of either party to insist, in one or more instances, on performance by the other in
strict accordance with the terms and conditions of this Agreement shall not be deemed a
waiver or relinquishment of any right granted hereunder or of the future performance of
any such term or condition or of any other term of condition of this Agreement, unless
such waivers contained in a writing signed by the party against whom the waiver or
relinquishment is sought to be enforced.
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13.     Notices

| | Any
notice or other communication to a party required or permitted hereunder shall be in a
writing and shall be deemed sufficiently given when received by the party (regardless of
the method of delivery), or if sent by registered or certified mail, postage and fees
prepaid, addressed to the party as follows, on the third business day after mailing:
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|(a) | If to Employer:          3130 Gateway Drive
|--- | -------------------------------------------
|    | Norcross, GA 30071                         

|(b) | If to Employee:          1992 Winchelsea Court
|--- | ----------------------------------------------
|    | Dunwoody, Georgia 30338                       

|or
in each case to such other address as the party may time to time designate in writing to
the other party.
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14.     Governing Law

| | This
Agreement shall be governed by and construed and enforced in accordance with the laws of
the State of Georgia.
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15.     
          Enforcement.

| | In
the event of any breach or threatened breach by Employee of any covenant contained in
Sections 9 or 10 hereof, the resulting injuries to the Company would be difficult or
impossible to estimate accurately, even though irreparable injury or damages would
certainly result. Accordingly, an award of legal damages, if without other relief, would
be inadequate to protect the Company. Employee, therefore, agrees that in the event of
any such breach, the Company shall be entitled to obtain from a court of competent
jurisdiction an injunction to restrain the breach or anticipated breach of any such
covenant, and to obtain any other available legal, equitable, statutory, or contractual
relief. Should the Company have cause to seek such relief, no bond shall be required from
the Company, and Employee shall pay all attorneys fees and court costs which the
Company may incur to the extent the Company prevails in its enforcement action.
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16.     Entire Agreement;
Modification and Amendment

| | This
Agreement contains the sole and entire agreement between the parties and supersedes all
prior discussions and agreements between the parties with respect to the matters
addressed herein, and any such prior agreement shall, from and after the date hereof, be
null and void. This Agreement and the attached Schedules shall not be modified or amended
except by an instrument in writing signed by the parties hereto.
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17.     
          Parties Benefited

| | This
Agreement shall insure to the benefit of, and be binding upon, Employee, his heirs,
executors and administrators, and Employer, its subsidiaries, affiliates, and successors.
| | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

IN
WITNESS WHEREOF, the parties hereto have executed and delivered this Agreement as of
the date first mentioned above.

| |                                                
| | -----------------------------------------------
| | IMMUCOR, INC.                                  
| |                                                
| |                                                
| | By:     _______________________________________
| | Edward L. Gallup, CEO                          

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# SCHEDULE A

EMPLOYMENT AGREEMENT DATED DECEMBER 1, 2003 BY AND BETWEEN IMMUCOR, INC. AND GIOACCHINO DE CHIRICO

Base compensation:  $315,000.00 a year payable in 26 installments every  two weeks.

Outplacement Assistance Benefit: $30,000.00.

Automobile Allowance: $9,600.00 a year payable in 12 monthly installments.

| |                                                  
| | -------------------------------------------------
| | IMMUCOR, INC.                                    
| |                                                  
| |                                                  
| | By:     _______________________________________  
| | Edward L. Gallup, CEO                            
| |                                                  
| | Date:     _______________________________________

(This Schedule A supersedes and
replaces any Schedule A previously executed by the parties hereto.)

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# SCHEDULE B

EMPLOYMENT AGREEMENT DATED DECEMDER 1, 2003 BY AND BETWEEN IMMUCOR, INC. AND GIOACCHINO DE CHIRICO

Life Insurance for the
Benefit of Employer: N/A

Insured:

Face Amount: $

Owner of Policy: Employer

Policy Number:

Insurance Company:

Life Insurance for the Benefit
of Employee:

Insured: Gioacchino De
Chirico.

Face Amount: $1,000,000.00

Owner of Policy: Employee

Policy Number:

Insurance Company:

| |                                                  
| | -------------------------------------------------
| | IMMUCOR, INC.                                    
| |                                                  
| |                                                  
| | By:     _______________________________________  
| | Edward L. Gallup, CEO                            
| |                                                  
| | Date:     _______________________________________

(This Schedule B supersedes and
replaces any Schedule B previously executed by the parties hereto.)