Exhibit 10.7

 

WORK ORDER NO. 8

 

THIS WORK ORDER NO. 8 is by and between RADIUS HEALTH, INC. (“RADIUS”) and LONZA Sales Ltd, a Swiss company having an address at Muenchensteinerstrasse 38, CH-4002 Basel, Switzerland (together with its Affiliates, “Manufacturer”), and upon execution will be incorporated into the Development and Manufacturing Services Agreement between RADIUS and Manufacturer dated October 16, 2007 (the “Agreement”). Capitalized terms in this Work Order will have the same meanings as set forth in the Agreement.

 

RADIUS hereby engages Manufacturer to provide Services, as follows:

 

1.                                      API/Drug Substance and Product.

 

BA058

 

Peptide Sequence:  H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2

 

2.                                      Services.  Manufacturer will render to RADIUS the following Services:

 

·                  Manufacturing of an RS solution and supply of 60 RS vials to Vetter: Price 5025€

·                  Supply of other powder samples to Vetter: Price 2015€

 

· 1 x 60task0 mg of RDS-001 / 3 AL1 (powder)

· 1x 100 mg de SF278 (powder)

· 2 x 100 mg de RDS-001-RS/8AK1R (powder)

· Transport of samples and vials to Vetter

 

·                  Stability on RS solution: Price 16200€

·                  VDS hold time study (analysis of 12 samples in duplicate): Price 3625€

 

Additional Services:

 

In addition the price for scanning batch records will be invoiced at 0.35€/page, it is estimated that there a few thousand pages to be scanned.

 

Timelines

 

Radius shall place purchase orders with Manufacturer in accordance with Work Order 8, and the work will be initiated upon receipt of the PO.

 

The deliverables will include regular updates (status reports, conference calls), as requested by RADIUS.

 

3.                                      Facilities.  The Services described above will be rendered at the Facility unless another facility of Manufacturer is indicated below:

 

N/A

 

4.                                      RADIUS Materials.  RADIUS will provide to Manufacturer the following materials to be used by Manufacturer to perform the Services:

 

None

 

5.                                      RADIUS Equipment.

 

None

 











 

6.                                      Manufacturer Representative.

 

Debra Sponholtz, Director, Sales and Business Development, Lonza

 

7.                                      RADIUS Representative.

 

David Hanley, Executive Director, Technical Operations

 

8.                          Compensation.  Radius will be invoiced 50% upon signature of this WO (€13,432.50) and 50% upon Completion of each Activity. The total compensation due Manufacturer for Services under this Work Order is not expected to exceed €26,865 excluding scanning of Batch records.

 

9.                          General: RADIUS and Manufacturer must agree in advance of either party making any change in the compensation due hereunder. Manufacturer will invoice RADIUS to the attention of David Hanley, for Services rendered under this Agreement.  Manufacturer will invoice RADIUS for all amounts due under this Work Order.  All undisputed payments will be made by RADIUS within thirty (30) days of receipt of invoice.

 

All other terms and conditions of the Agreement will apply to this Work Order.    Reviewed by AH

 

	
WORK ORDER AGREED TO AND   ACCEPTED BY:
    	
 
    	
 
    	
Legal Department
    
	
 
    	
 
    	
 
    	
 
    
	
RADIUS HEALTH, INC.
    	
 
    	
LONZA SALES LTD
    	
 
    
	
 
    	
 
    	
 
    	
 
    
	
By
    	
/s/ David C. Hanley
    	
 
    	
By
    	
 /s/ Marie Leblanc
    	
 
    	
/s/ Nadia Zieger
    
	
 
    	
 
    	
 
    	
 
    	
 
    
	
 
    	
 
    	
 
    	
Associate Director
    
	
 
    	
 
    	
 
    	
 
    
	
 
    	
 
    	
 
    	
Key Account Management
    
	
 
    	
 
    	
 
    	
 
    
	
Print Name
    	
David C. Hanley
    	
 
    	
Print Name
    	
Nadia Zieger
    
	
Title
    	
Executive Director
    	
 
    	
Title
    	
Senior Legal Counsel
    
	
Date
    	
25 Mar 2015
    	
 
    	
Date
    	
27 Mar 2015