LOAN MODIFICATION AGREEMENT NO. 2

     This Loan Modification Agreement No. 2 (this "Agreement"), dated as of July
18, 2002 (the  "Effective  Date"),  is made  between  IMMUCOR,  INC.,  a Georgia
corporation ("U.S.  Borrower"),  DOMINION  BIOLOGICALS LIMITED, the successor by
amalgamation   to  3000524  Nova  Scotia   Limited  and  itself  a   corporation
incorporated  under  the  laws of  Canada  ("Canadian  Borrower"),  and  IMMUCOR
MEDIZINISCHE  DIAGNOSTIK GMBH, a corporation  incorporated under the laws of the
Federal Republic of Germany ("German Borrower"; U.S. Borrower, Canadian Borrower
and German Borrower,  individually and collectively,  "Borrower"),  as borrower,
and WACHOVIA BANK,  NATIONAL  ASSOCIATION,  a national banking  association,  as
lender  ("Lender") for the purpose of amending or otherwise  modifying the terms
of that certain Loan Agreement,  dated as of February 23, 2001,  heretofore made
between  Lender  and  Borrower  (which,  as it has been,  or  hereafter  may be,
modified or amended, is called herein the "Loan Agreement"),  as amended by that
Loan  Modification  Agreement No. 1 amongst  Borrower and the Lender dated as of
September 11, 2001 ("Loan Modification Agreement No. 1").

                                   Background

     Borrower and Lender previously entered into Loan Modification Agreement No.
1 which waived certain prior defaults by Borrower under the Loan Agreement. Such
waivers were conditioned upon, among other things, the receipt prior to December
31, 2001 by the U.S.  Borrower of an investment of at least Five Million Dollars
($5,000,000)  subordinated to all Obligations of each Credit Party to Lender and
which  would be applied  to reduce  the  outstanding  Obligations  (the  "Junior
Capital Infusion").

     The U.S.  Borrower  has not  obtained  the Junior  Capital  Infusion.  As a
result, (i) U.S. Borrower became liable to Lender for a supplemental waiver fee;
(ii) U.S.  Borrower  became  obligated  to issue to Lender a warrant to purchase
from the U.S.  Borrower  750,000  shares of voting common stock (which,  in lieu
thereof,  Lender  subsequently  agreed to accept  certain  fees),  (iii) certain
interest rates under the Loan Documents  increased;  and (iv) the maturity dates
of all existing credit facilities advanced to February 28, 2003.

     Borrower and Lender make this Loan Modification Agreement No. 2 in order to
amend certain terms and conditions of the Loan Agreement, including the maturity
dates, the applicable interest rates, and the loan covenants.

     Now,  therefore,  in consideration of the mutual promises  contained herein
and in the Loan  Agreement,  the  receipt  and  sufficiency  of which are hereby
acknowledged,  Lender and Borrower, each intending to be legally bound, agree as
follows:

1.   Definitions.  Capitalized  terms used  herein,  but not  expressly  defined
     themselves herein,  shall have the meanings given to such terms in the Loan
     Agreement or in Loan Modification Agreement No. 1.
<PAGE>

2.   Loan Modifications.  Lender and Borrower agree to modify the Loan Agreement
     as follows:

2.1  Change in  Termination  Dates.  Notwithstanding  the failure by Borrower to
     obtain the Junior Capital  Infusion,  the  termination or maturity dates of
     the Obligations shall be amended as follows:

(a)  Revolvers.  Commencing on the Effective  Date, the Loan Agreement is hereby
amended to provided that each of the U.S.  Line of Credit,  the Canadian Line of
Credit,  and the German Line of Credit will  terminate no later than December 1,
2005.

(b) Term Loan A and Term Loan B.  Borrower  shall make payments of principal and
interest  under  Term Loan A and Term  Loan B in  accordance  with the  original
payment  schedule as provided in the Loan  Agreement  dated  February  23, 2001.
Specifically,  the  principal  amount of Term Loan A shall be repaid by the U.S.
Borrower in twenty (20) quarterly  installments on each Payment Date, commencing
on March 1, 2001, the first four (4) of which shall be in the amount of $375,000
each, the next four (4) of which shall be in the amount of $875,000 each and the
next twelve (12) of which shall be in the amount of $1,250,000  each;  provided,
however,  that the final such installment,  due and payable on December 1, 2005,
shall be in such  amount  as is  required  to pay in full the  unpaid  principal
balance of Term Loan A, together with all accrued and unpaid  interest  thereon;
and the  principal  amount of Term Loan B,  together with all accrued and unpaid
interest thereon, shall be due and payable in full on December 1, 2005.

(c) Canadian Term Loan. The outstanding  principal  balance of the CAD Term Loan
shall continue to be repaid by the U.S.  Borrower in quarterly  installments  in
accordance  with the  amortization  schedule  set  forth  in the CAD Term  Note;
provided,  however,  that the final  such  installment,  which  shall be due and
payable on September  1, 2002,  shall be in such amount as is required to pay in
full the  unpaid  principal  balance  of the CAD Term  Loan,  together  with all
accrued and unpaid interest thereon.

2.2  Change in Interest  Rate.  Commencing  on the Effective  Date,  Subsections
     2.1(a) and 2.1(b) of the Loan Agreement shall be


     (a) Applicable Rate.

          (i) The  outstanding  principal  balance of each Loan (other than Term
     Loan B), or each outstanding portion thereof, shall bear interest initially
     at a rate per annum equal to either: (i) the Prime Rate in the case of that
     portion of such Loan at any time  constituting  a Prime  Borrowing  or (ii)
     subject to the  conditions  and  limitations  set forth in  subsection  (c)
     below,  the  LIBOR  Rate  plus the  Applicable  Margin  in the case of that
     portion of such Loan at any time  constituting a LIBOR Borrowing;  subject,
     however, in each case, to adjustment as provided in subsection (b) below.
<PAGE>

          (ii) The  outstanding  principal  balance  of Term  Loan B shall  bear
     interest  initially at a rate per annum equal to either: (i) the Prime Rate
     plus  one-half of one percent  (0.5%),  in the case of that portion of such
     Loan at any time  constituting  a Prime  Borrowing,  or (ii) subject to the
     conditions and  limitations  set forth in subsection  (c) below,  the LIBOR
     Rate plus the Applicable  Margin,  in the case of that portion of such Loan
     at any time constituting a LIBOR Borrowing; subject, however, in each case,
     to adjustment as provided in subsection (b) below.

          (b) Applicable  Margin.  The "Applicable  Margin" shall mean as of the
     Effective  Date a rate per annum equal to, with  respect to Advances  under
     the Lines of Credit,  the Term Loan A 200 basis points  (2.00%)  and,  with
     respect to the Term Loan B, 250 basis points  (2.50%),  and the  Applicable
     Margin shall be subject to subsequent adjustment,  up or down, based on the
     U.S.  Borrower's  financial  performance,  determined  by  reference to the
     Funded  Debt/EBITDA  Ratio,  measured  quarterly;  that is,  if the  Funded
     Debt/EBITDA  Ratio,  measured for each Fiscal Quarter of the U.S. Borrower,
     commencing  with the first Fiscal Quarter ending after the Effective  Date,
     is as described below, the Applicable  Margin shall be the margin appearing
     opposite said Funded Debt/EBITDA Ratio:


                                Applicable Margin
         ----------------------------------------------------------------------
                    Funded Debt/         Lines of Credit,
         Level      EBITDA Ratio         and Term Loan A       Term Loan B
         ------  -------------------    ------------------  -----------------

         I          <1.75:1.00                2.00%               2.50%

         II         >1.75:1.00, but           2.50%               3.00%
                    < 2.25:1.00

         III        >2.25:1.00                2.75%               3.25%



Lender shall determine  whether any adjustment to the Applicable Margin is to be
made  quarterly,  based on the U.S.  Borrower's  financial  statements  for each
Fiscal  Quarter  delivered to Lender  pursuant to Section 4.2;  provided that if
such financial statements are not timely delivered to Lender, then an adjustment
to the  Applicable  Margin  shall be made based on an assumed  delivery  of said
financial  statements  reflecting  a Funded  Debt/EBITDA  Ratio of greater  than
2.25:1.0;  i.e., Level III above.  Each such adjustment to the Applicable Margin
shall become  effective as of the first day of the calendar month  following the
date on which such financial  statements are delivered (or deemed  delivered) to
Lender,  and shall remain effective  unless and until any subsequent  adjustment

<PAGE>

becomes  effective in accordance with the terms of this Section  2.2.1(b).  Each
such adjustment shall apply only to LIBOR Borrowings made (including conversions
and  continuations)  within such period (but not to any then  existing).  In the
event that the annual audited financial  statements of the U.S. Borrower for any
Fiscal  Year shall  require  restatement  of  financial  statements  of the U.S.
Borrower  and such  restatement  shall affect the Funded  Debt/EBITDA  Ratio and
would have  required  a  different  Applicable  Margin to be in effect for prior
period(s),  then Lender, at its option,  may require Borrower to make additional
payments of interest for such prior period(s).

2.3  Change in Non-Usage Fee. Subsection 2.2.2(b) of the Loan Agreement shall be
     amended and restated to read as set forth below:

               (v) For purposes hereof,  the term "Applicable  Percentage" shall
          mean as of the Effective Date,  one-quarter of one percent (.25%), and
          the Applicable  Percentage shall be subject to subsequent  adjustment,
          up or down, based on the U.S. Borrower's financial  performance,  on a
          quarterly basis, commencing with the first Fiscal Quarter ending after
          the Effective  Date, as set forth in the table below (with  references
          to  Levels I  through  III below  corresponding  to the same  Levels I
          through III in Section 2.2.1):

                          LEVEL                    APPLICABLE PERCENTAGE

                          I                               .250%
                          II                              .375%
                          III                             .500%

               Lender shall  determine  whether any adjustment to the Applicable
          Percentage  is to be made  quarterly,  based  on the  U.S.  Borrower's
          financial  statements  for each  Fiscal  Quarter  delivered  to Lender
          pursuant to Section 4.2;  provided that if such  financial  statements
          are  not  timely  delivered  to  Lender,  then  an  adjustment  to the
          Applicable  Percentage  shall be made based on an assumed  delivery of
          such financial  statements  reflecting a Funded  Debt/EBITDA  Ratio of
          greater than 2.25:1.00; i.e., Level III above; provided further if any
          Default Condition shall exist no adjustment downward shall occur. Each
          such adjustment to the Applicable Percentage shall become effective as
          of the first day of the  calendar  month  following  the date on which
          such  financial  statements  are  delivered  (or deemed  delivered) to
          Lender,  and shall remain  effective  unless and until any  subsequent
          adjustment  becomes  effective  in  accordance  with the terms of this
          Section  2.2.2(b).  In the event  that the  annual  audited  financial
          statements  of the U.S.  Borrower  for any Fiscal  Year shall  require
          restatement  of  financial  statements  of the U.S.  Borrower and such
          restatements  shall affect the Funded Debt/EBITDA Ratio and would have
          required a different  Applicable  Percentage to be in effect for prior
          period(s),  then Lender,  at its option,  may require Borrower to make
          additional payments of interest for such prior period(s).

2.4  Annual  Commitment  Fee.  There  shall be added to the Loan  Agreement  the
     following Subsection 2.2(c):
<PAGE>

               (c) Annual  Commitment  Fee.  Commencing on July 1, 2003,  and on
          each anniversary  thereof while Lender has an obligation to lend under
          any of the  Lines of  Credit,  Borrower  shall  pay to  Lender a fully
          earned, non-refundable annual commitment fee in an amount equal to the
          product of (i)  one-eighth  of one  percent  (.125%) of the sum of the
          U.S.  Line of Credit Limit plus the Dollar  Equivalent of the Canadian
          Line of Credit Limit plus the Dollar  Equivalent of the German Line of
          Credit Limit outstanding on May 31 of such year, (ii) times the lesser
          of (x) 1.00 or (y) a fraction, the numerator of which is the number of
          days  from  July 1 of  such  year  until  December  1,  2005,  and the
          denominator of which is 365 days.

2.5  Roll Forward of Other Fees.  There shall be added to the Loan Agreement the
     following Subsection 2.2(d):

               (d) Other Fees. To  memorialize  those fees now owing pursuant to
          Loan  Modification   Agreement  No.  1  and  certain  agreements  made
          subsequent  thereto in exchange for Lender's waiver of the requirement
          for delivery of the Warrants described therein, Borrower acknowledges,
          confirms  and agrees that Lender has earned,  and Borrower is bound to
          pay Lender the following fees on the dates prescribed below,  provided
          that  upon any  acceleration  of all  Obligations,  all such fees then
          shall become due and payable in full:


                     Restructuring  Fee for Missing    In Lieu of
         Date (EOM)       Fee        12/31 Deadline    Warrant Fee       Total

         2002
         July           $62,500         $37,500                        $100,000
         August         $62,500         $37,500                        $100,000
         September                      $37,500        $  75,000       $112,500
         October                        $37,500        $  75,000       $112,500
         November                       $37,500        $  75,000       $112,500
         December                       $37,500        $  75,000       $112,500

         2003
         January                                       $ 100,000       $100,000
         February                                      $ 100,000       $100,000


2.6  Changes in Financial Covenants.

(a)  Definitions.  The definitions of "Fixed Charge Coverage Ratio and "Leverage
Ratio" shall be amended and restated to read as follows:  "Fixed Charge Coverage
Ratio"  shall mean,  with respect to any Person and for any fiscal  period,  the
ratio of (i) such Person's  EBITDA for the  consecutive  12-month  period ending
with such period,  minus such Person's Taxes for the consecutive 12-month period
ending with such period, to (ii) such Person's Fixed Charges for the consecutive
12-month  period ending with such period,  all as  determined on a  consolidated
basis;  and "Leverage  Ratio" shall mean, with respect to any Person and for any
fiscal  period,  the  ratio of (i) the sum of such  Person's  total  liabilities
(including  accrued  and  deferred  income  taxes) as at the end of such  fiscal
period to (ii) such Person's Net Worth as at the end of such fiscal period,  all
as determined on a consolidated basis.
<PAGE>

(b) Fixed Charge  Coverage  Ratio.  Section 6.1 of the Loan  Agreement  shall be
amended and restated to read as set forth below:

     6.1 Fixed Charge Coverage  Ratio.  The U.S.  Borrower and its  Consolidated
     Subsidiaries shall have for each Fiscal Quarter ending closest to each date
     set forth below,  a Fixed Charge  Coverage  Ratio of not less than that set
     forth below for such period:

                                                              Minimum Fixed
     Fiscal Quarter Ending:                               Charge Coverage Ratio:
     ---------------------                                ---------------------

     Quarters ending August 31, 2002 through May 31, 2003       1.20:1.00

     Quarters ending August 31, 2003 through May 31, 2004       1.35:1.00

     Thereafter                                                 1.45:1.00

(c)  Funded Debt to EBITDA.  Section 6.2 of the Loan Agreement  shall be amended
     and restated to read as set forth below:

     6.2  Funded  Debt/EBITDA  Ratio.  The U.S.  Borrower  and its  Consolidated
     Subsidiaries shall have for each Fiscal Quarter ending closest to each date
     set forth below a Funded  Debt/EBITDA Ratio of not more than that set forth
     below for such period:


                                                       Maximum Funded
         Fiscal Quarter Ending:                        Debt/EBITDA Ratio:
         ---------------------                         -----------------
         Quarters ending August 31, 2002                   2.50:1.00
                 through May 31, 2003

         Thereafter                                        2.00:1.00

          Solely for  purposes of this  Section  6.2, so long as any Debt of the
          U.S.  Borrower  or any of its  Consolidated  Subsidiaries  is,  by its
          terms,  expressly subordinated to the obligations of such Credit Party
          to Lender, including,  without limitation,  all Obligations,  on terms
          and conditions  satisfactory to Lender in its sole discretion,  and so
          long  as  Lender  determines,  in  its  sole  discretion,   that  such
          subordination  is  and  continues  to be in  all  respects  valid  and
          enforceable against the holders of such obligations, such subordinated
          Debt shall not be included as Funded Debt; provided, however, that the
          foregoing  shall  not be  deemed  to be a  consent  by  Lender  to the
          incurrence by any Credit Party of any Debt not otherwise  permitted to
          be incurred pursuant to Section 5.2.
<PAGE>

(d)  Leverage  Ratio.  Section  6.3 of the Loan  Agreement  shall be amended and
     restated to read as set forth below:

          6.3  Leverage   Ratio.   The  U.S.   Borrower  and  its   Consolidated
          Subsidiaries shall have for each Fiscal Quarter ending closest to each
          date set forth below, a Leverage Ratio of not less than that set forth
          below for such period:

         Fiscal Quarter Ending:                                 Leverage Ratio:
         ---------------------                                  --------------

         Quarters ending August 31, 2002 through May 31, 2003      1.75:1.00

         Quarters ending August 31, 2003 through May 31, 2004      1.50:1.00

         Thereafter                                                1.25:1.00

(e)  CAPEX.  Section 5.14 of the Loan Agreement shall be amended and restated to
     read as set forth below:

     5.14 Certain Capital  Expenditures.  The U.S. Borrower and its Subsidiaries
          shall not make Capital  Expenditures to acquire equipment for lease to
          their customers in an aggregate amount in excess of $3,500,000  during
          any Fiscal Year.

2.7 Change in Borrowing Base and Borrowing Base Reporting.

(a) Definition of "Eligible  Accounts."  The  definition of "Eligible  Accounts"
shall be amended  and  restated to mean,  collectively,  the  Eligible  Domestic
Entity Accounts and the Eligible Foreign Entity Accounts, other than any account
receivable generated as a result of selling instruments.

(b) Definition of "Borrowing  Base." The definition of "Borrowing Base" shall be
amended and restated to mean the  aggregate  of the  following  amounts:  (i) an
amount  equal to eighty (80%) of the Dollar  value of Eligible  Domestic  Entity
Accounts  plus (ii) an amount equal to  forty-five  percent  (45%) of the Dollar
value of Eligible  Foreign  Entity  Accounts  plus (iii) an amount  equal to the
lesser of (A) fifty percent  (50%) of the Dollar value of Eligible  Inventory or
(B) fifty  percent (50%) of the amount of Advances  outstanding  pursuant to the
preceding clauses (i) and (ii) minus (iii) Borrowing Base Reserves.

(c) Weekly  Delivery of Borrowing  Base  Certificate.  Provided that no Event of
Default occurs, and  notwithstanding any provision of Section 4.2.10 of the Loan
Agreement  to the  contrary,  until May 31,  2003,  Borrower  shall  deliver the
Borrowing Base  Certificate on a weekly basis, as soon as practicable  after the
end of each  calendar  week,  but not later than the second  Business Day of the
succeeding calendar week, reflecting weekly updates of the information specified
in said Section 4.2.10 for the U.S. Borrower and its Subsidiaries, and

<PAGE>

monthly  updates of such  information  for the German  Borrower and the Canadian
Borrower.  Subsequent to May 31, 2003, provided that no Event of Default occurs,
delivery of the Borrowing  Base  Certificate  shall resume on a monthly basis in
accordance  with  said  Section  2.4.10.  In  addition  to  the  foregoing,  the
requirement for delivery of weekly Cash Flow projections,  prescribed in Section
5 of Loan  Modification  Agreement No. 1 shall continue  without  abatement both
before and after May 31, 2003.

(d) Field Exams.  Unless and except to the extent that any Event of Default then
exists,  the  obligation  of  Borrower  to  reimburse  Lender  for field  audits
conducted by it pursuant to Section 9.6 of the Loan  Agreement  shall be limited
to not more than:  (i) one (1) field audit during the remainder of calendar year
2002;  (ii) two (2) field audits during  calendar  year 2003;  and (iii) one (1)
field audit per calendar  year  thereafter;  it being  understood  that Lender's
standard  audit fee has changed from a flat $2,500 per audit plus  out-of-pocket
expenses to $750 per auditor per diem plus out-of-pocket expenses.

3.  Inducing  Representations.  To induce  Lender to enter into this  Agreement,
Borrower hereby represents and warrants that: (i) Borrower is duly authorized to
enter into this Agreement,  and this  Agreement,  upon its execution by Borrower
and Lender,  will constitute  Borrower's  legal,  valid and binding  obligations
enforceable  in accordance  with its terms against  Borrower;  (ii) after giving
effect to this Agreement,  no Event of Default exists; (iii) no present right of
setoff, counterclaim, recoupment claim, claim, cause or action or defense exists
in Borrower's  favor in respect of its payment or performance of any Obligations
or arising from any action (or inaction) of Lender;  and (iv) except as modified
by this Agreement, all terms of the Loan Agreement and each Loan Document are in
full force and effect as originally stated.

4.   Miscellaneous.   Except  as  otherwise   expressly   provided  herein,  all
modifications  to the Loan  Agreement  set forth herein shall take effect on the
Effective Date. Each existing Loan Document (including,  particularly, any Note)
shall be deemed  modified  hereby as necessary to conform its terms to the terms
of the Loan Agreement,  as modified  hereby.  This Agreement  constitutes a Loan
Document,  and shall be  governed  and  construed  accordingly.  This  Agreement
constitutes  the entire  agreement  between Lender and Borrower  relative to the
subject matter hereof, and supersedes and replaces any prior  understandings and
agreements,  written or oral, in regard thereto. This Amendment shall be binding
on, and inure to the benefit  of, the  successors  and  assigns of Borrower  and
Lender.  Borrower  shall  reimburse  Lender for all costs which  Lender  incurs,
including reasonable attorneys fees, in the preparation,  negotiation, execution
and  performance of this  Agreement,  and the recording of any Loan Documents in
connection herewith.

     IN WITNESS  WHEREOF,  the parties  hereto have caused this  Agreement to be
executed as of the day and year first above written.


<PAGE>



                                   WACHOVIA BANK,
                                   NATIONAL ASSOCIATION


                                   By:
                                      --------------------------------
                                   Name:
                                        ------------------------------
                                   Title:
                                         -----------------------------


                    (SIGNATURES CONTINUED ON FOLLOWING PAGE)


<PAGE>


                                    IMMUCOR, INC.


                                    By:
                                       --------------------------------
                                    Name: Steven C. Ramsey
                                    Title: Chief Financial Officer



                    (SIGNATURES CONTINUED ON FOLLOWING PAGE)


<PAGE>


                                    DOMINION BIOLOGICALS LIMITED


                                    By:
                                       --------------------------------
                                       Name: Steven C. Ramsey
                                       Title: Vice President

                    (SIGNATURES CONTINUED ON FOLLOWING PAGE)



<PAGE>


                                        IMMUCOR MEDIZINISCHE DIAGNOSTIK GMBH


                                        By:
                                           --------------------------------
                                           Name: Edward L. Gallup
                                           Title: Managing Director