May 2014

1

Toxicity and Bioaccumulation Factors Used in the Draft 2014 

Updated Ambient Water Quality Criteria for the Protection of Human Health

Chemical Pollutant

CAS 

Number

*Reference 

Dose (RfD)

(mg/kg·d)

*Cancer 

Slope Factor 

(CSF)

(kg·d/mg)

*Bioaccumulation Factor (BAF) (L/kg)

Trophic 

Level 2

Trophic 

Level 3

Trophic 

Level 4

Acenaphthene 83-32-9 0.06 --- 123.1 116.4 94.95

Acrolein 107-02-8 0.0005 --- 0.992 0.9891 0.9705

Acrylonitrile 107-13-1 --- 0.54 1.034 1.036 1.033

Aldrin 309-00-2 --- 17 222,600 207,700 184,000

alpha-BHC 319-84-6 --- 6.3 934.9 1,118 1,935

alpha-Endosulfan 959-98-8 0.006 --- 375.6 409.7 544.4

Anthracene 120-12-7 0.3 --- 1,212 1,169 1,151

Benzene 71-43-2 --- 0.015-0.055 8.9 10.01 14.79

Benzidine 92-87-5 --- 230 2.195 2.354 2.992

Benzo(a) Anthracene 56-55-3 --- 0.29 1,577 748.7 405.5

Benzo(a) Pyrene 50-32-8 --- 2.9 2,736 983.7 395.6

Benzo(b) Fluoranthene 205-99-2 --- 0.29 5,325 2,643 1,165

Benzo(k) Fluoranthene 207-08-9 --- 0.29 1,883 675.5 300.5

beta-BHC 319-85-7 --- 1.8 934.9 1,118 1,935

beta-Endosulfan 33213-65-9 0.006 --- 178.9 199.2 281.1

Bis(Chloromethyl) Ether 542-88-1 --- 2.2E+02 1.149 1.166 1.225

Bis(2-Chloroethyl) Ether 111-44-4 --- 1.1 2.028 2.156 2.639

**Bis(2-Chloro-1-Methylethyl) 

Ether 108-60-1 0.04 --- 13.48 14.23 15.63

Bis(2-Ethylhexyl) Phthalate 117-81-7 --- 0.014 17,370 6,120 1,040

Bromoform 75-25-2 --- 0.0046 13.85 15.18 19.49

Butylbenzyl Phthalate 85-68-7 0.2 --- 62.46 54.54 40.08

Carbon Tetrachloride 56-23-5 --- 0.07 20.02 20.11 18.82

Chlordane 57-74-9 --- 0.35 688,200 1,318,000 3,205,000

Chlorobenzene 108-90-7 0.02 --- 24.41 25.05 25

Chlorodibromomethane 124-48-1 --- 0.043 8.723 9.616 12.78

Chloroform 67-66-3 0.01 --- 6.003 6.591 8.706

Chlorophenoxy Herbicide (2,4-

D) 94-75-7 0.05 --- 39.49 44.92 68.75

Chlorophenoxy Herbicide 

(2,4,5-TP) 93-72-1 0.008 --- 389.7 441.9 662.9

Chrysene 218-01-9 --- 0.029 8,997 4,739 1,993

Cyanide 57-12-5 0.0006 --- 0.9634 0.9561 0.9202

Dibenzo(a,h) Anthracene 53-70-3 --- 4.1 24,690 10,700 2,863

Dichlorobromomethane 75-27-4 --- 0.035 6.562 7.269 10.01

Dieldrin 60-57-1 --- 16 17,280 20,740 30,820

Diethyl Phthalate 84-66-2 0.8 --- 6.747 6.636 5.889

Dimethyl Phthalate 131-11-3 10 --- 2.066 2.065 1.953

Di-n-Butyl Phthalate 84-74-2 0.1 --- 236.2 209.4 159.4

Dinitrophenols 25550-58-7 0.002 --- 1.808 1.835 1.833

Endosulfan Sulfate 1031-07-8 0.006 --- 255 281 383

Endrin 72-20-8 0.0003 --- 17,280 20,740 30,820

Endrin Aldehyde 7421-93-4 0.0003 --- 5,409 6,428 10,070

Ethylbenzene 100-41-4 0.1 --- 61.51 65.33 73.56

Fluoranthene 206-44-0 0.04 --- 790.1 563.4 388.4

Fluorene 86-73-7 0.04 --- 763 789.7 909.2

gamma-BHC (Lindane) 58-89-9 0.0047 --- 934.9 1,118 1,935
2

Heptachlor 76-44-8 --- 4.5 31,680 33,940 39,160

Heptachlor Epoxide 1024-57-3 --- 9.1 11,850 19,230 55,830

Hexachlorobenzene 118-74-1 --- 1.6 157,300 294,000 791,100

Hexachlorobutadiene 87-68-3 --- 0.04 6,044 8,953 23,410

HexachlorocyclohexaneTechnical 608-73-1 --- 1.8 1,270 1,534 2,705

Hexachlorocyclopentadiene 77-47-4 0.006 --- 7,310 6,930 6,502

Hexachloroethane 67-72-1 --- 0.04 727.1 762.8 912.6

Ideno(1,2,3-cd) Pyrene 193-39-5 --- 0.29 5,370 1,465 316.6

Isophorone 78-59-1 --- 9.5E-04 3.301 3.493 3.992

Methoxychlor 72-43-5 0.005 --- 8,963 8,860 9,001

Methyl Bromide 74-83-9 0.02 --- 1.795 1.891 2.243

Methylene Chloride 75-09-2 --- 0.0033 1.968 2.098 2.63

Nitrobenzene 98-95-3 0.002 --- 4.669 5.072 6.433

Pentachlorobenzene 608-93-5 0.0008 --- 19,630 28,470 61,860

Pentachlorophenol 87-86-5 --- 0.4 486.1 360.9 254.7

Phenol 108-95-2 0.3 --- 2.193 2.27 2.419

Pyrene 129-00-0 0.03 --- 1,322 1,058 784.9

Tetrachloroethylene 127-18-4 --- 0.002 54.22 52.97 46.04

Toluene 108-88-3 0.08 --- 27.6 30.14 37.79

Toxaphene 8001-35-2 --- 1.1 117,800 163,300 278,100

Trichloroethylene 79-01-6 --- 0.05 15.43 17.18 23.7

Vinyl Chloride 75-01-4 --- 1.4 3.343 3.652 4.892

1,1,1-Trichloroethane 71-55-6 2 --- 10.55 10.7 10.32

1,1,2,2-Tetrachloroethane 79-34-5 --- 0.2 13.72 15.08 19.6

1,1,2-Trichloroethane 79-00-5 --- 0.057 4.91 5.312 6.585

1,1-Dichloroethylene 75-35-4 0.05 --- 8.186 9.012 11.93

1,2,4-Trichlorobenzene 120-82-1 0.01 --- 642.8 714.7 1,010

1,2,4,5-Tetrachlorobenzene 95-94-3 0.0003 --- 3,696 4,798 9,639

1,2-Dichlorobenzene 95-50-1 0.3 --- 151.5 168.6 235.6

1,2-Dichloroethane 107-06-2 --- 0.091 2.67 2.89 3.777

1,2-Dichloropropane 78-87-5 --- 0.036 5.664 6.106 7.414

1,2-Diphenylhydrazine 122-66-7 --- 0.8 41.47 44.73 53.3

1,2-Trans-Dichloroethylene 156-60-5 0.02 --- 6.731 7.507 10.71

1,3-Dichlorobenzene 541-73-1 0.002 --- 134.3 140.1 149.5

1,3-Dichloropropene 542-75-6 --- 0.1 7.137 7.965 11.38

1,4-Dichlorobenzene 106-46-7 0.07 --- 165.7 187.5 281.3

2,4,5-Trichlorophenol 95-95-4 0.1 --- 190.4 195 198.5

2,4,6-Trichlorophenol 88-06-2 --- 0.011 109.6 106.9 93.59

2,4-Dichlorophenol 120-83-2 0.003 --- 35.28 35.65 33.95

2,4-Dimethylphenol 105-67-9 0.02 --- 9.984 10.67 12.33

2,4-Dinitrophenol 51-28-5 0.002 --- 2.697 2.765 2.814

2,4-Dinitrotoluene 121-14-2 --- 0.667 6.485 7.232 10.33

2-Chloronaphthalene 91-58-7 0.08 --- 440.4 477.8 626.2

2-Chlorophenol 95-57-8 0.005 --- 8.957 9.989 14.07

2-Methyl-4,6-Dinitrophenol 534-52-1 0.0004 --- 4.757 4.771 4.485

3,3'-Dichlorobenzidine 91-94-1 --- 0.45 138.1 145.6 162.1

3-Methyl-4-Chlorophenol 59-50-7 0.1 --- 23.02 22.24 18.76

4,4'-DDD 72-54-8 --- 0.24 370,200 678,800 1,636,000

4,4'-DDE 72-55-9 --- 0.167 463,100 573,300 775,200

4,4'-DDT 50-29-3 --- 0.34 1,022,000 1,446,000 2,315,000

*See chemical pollutant specific human health ambient water quality criteria documents for references for these inputs.

**Bis(2-Chloro-1-Methylethyl) Ether was previously listed as Bis(2-Chloroisopropyl) Ether.