Federal Register / Vol. 88, No. 170 / Tuesday, September 5, 2023 / Notices 60695 

FOR FURTHER INFORMATION CONTACT: 

Sheila Garrity, JD, MPH, MBA, Director, 

Office of Research Integrity, 1101 

Wootton Parkway, Suite 240, Rockville, 

MD 20852, (240) 453–8200. 

SUPPLEMENTARY INFORMATION: Notice is 

hereby given that the Office of Research 

Integrity (ORI) has taken final action in 

the following case: 

Ivana Frech, Ph.D. (formerly Ivana De 

Domenico), University of Utah: Based 

on the evidence and findings of an 

investigation conducted by UU, ORI’s 

oversight review of UU’s investigation, 

and additional analysis conducted by 

ORI during its oversight review, ORI 

found that Ivana Frech, Ph.D. (formerly 

Ivana De Domenico), former Assistant 

Professor, Department of Internal 

Medicine, UU School of Medicine, 

engaged in research misconduct under 

42 CFR part 93 in research supported by 

PHS funds, specifically NIDDK, NIH, 

grants R01 DK070947, R01 DK090257, 

and R01 DK030534, NIGMS, NIH, grant 

P50 GM082545, NIAID, NIH, grant R01 

AI051174, and NHLBI, NIH, grant R01 

HL026922. 

ORI found by a preponderance of the 

evidence that Respondent intentionally, 

knowingly, or recklessly falsified and/or 

fabricated western blot and 

autoradiogram images related to 

mechanisms of cellular iron regulation 

by reusing, relabeling, and manipulating 

images to falsely report data in eight (8) 

figures included in the following three 

(3) PHS-supported published papers: 

• Two Distinct Modes of ESCRT–III 

Recognition are Required for VPS4 

Functions in Lysosomal Protein 

Targeting and HIV–1 Budding. Dev Cell. 

2008 Jul;15(1):62–73. doi: 10.1016/ 

j.devcel.2008.05.014 (hereafter referred 

to as ‘‘Dev. Cell 2008’’). 

• The Role of Ubiquitination in 

Hepcidin-independent and Hepcidindependent Degradation of Ferroportin. 

Cell Metab. 2011 Nov 2;14(5):635–46. 

doi: 10.1016/j.cmet.2011.09.008 

(hereafter referred to as ‘‘Cell Met. Nov. 

2011’’) Retracted: Cell Met. 2012 Jun 

6;15(6):927. doi: 10.1016/ 

j.cmet.2012.04.107. 

• Decoupling Ferritin Synthesis from 

Free Cytosolic Iron Results in Ferritin 

Secretion. Cell Metab. 2011 Jan 

5;13(1):57–67. doi: 10.1016/ 

j.cmet.2010.12.003 (hereafter referred to 

as ‘‘Cell Met. Jan. 2011’’). Retracted: Cell 

Met. 2012 Jun 6;15(6):927. doi: 10.1016/ 

j.cmet.2012.04.012. 

ORI found that these acts constitute a 

significant departure from accepted 

practices of the relevant research 

community. Specifically, ORI found by 

a preponderance of the evidence that 

Respondent engaged in research 

misconduct by intentionally, 

knowingly, or recklessly falsifying and/ 

or fabricating: 

• a western blot image in Figure 5B 

(right bottom panel) of Dev. Cell 2008 

by reusing and relabeling an image of 

three western blot bands to represent 

the results of different experiments 

• western blot images in Figure 1C (top 

and bottom panels) of Cell Met. Nov. 

2011 by reusing and relabeling an 

image of western blot bands to 

represent the results of two different 

experiments 

• western blot images in Figures 1D and 

3 of Cell Met. Nov. 2011 by reusing 

and relabeling one image to represent 

the results of two different 

experiments 

• western blot images in Figures 2Aii 

and 2B of Cell Met. Nov. 2011 by 

reusing and relabeling one image as 

representing the results of two 

different experiments 

• western blot images in Figures 2Aii 

and 5 of Cell Met. Nov. 2011 by 

reusing and relabeling one image as 

representing the results of two 

different experiments 

• images in Figure 4B (top and bottom 

left panels) of Cell Met. Jan. 2011 by 

reusing and relabeling an image of an 

autoradiogram to misrepresent the 

reported experimental conditions and 

results 

The following administrative actions 

have been implemented: 

(1) For a period of three (3) years, 

beginning on August 21, 2023, 

Respondent is debarred from 

participating in ‘‘covered transactions’’ 

as defined in 42 CFR 180.200 and 

procurement transactions covered under 

the Federal Acquisition Regulation (48 

CFR chapter 1). 

(2) Respondent is prohibited from 

serving in any advisory capacity to PHS 

including, but not limited to, service on 

any PHS advisory committee, board, 

and/or peer review committee, or as a 

consultant for a period of three (3) years, 

beginning on August 21, 2023. 

(3) In accordance with 42 CFR 

93.407(a)(1) and 93.411(b), HHS will 

send to the journal Developmental Cell 

a notice of ORI’s findings and the need 

for retraction or correction of Dev Cell. 

2008 Jul;15(1):62–73. doi: 10.1016/ 

j.devcel.2008.05.014. 

Dated: August 30, 2023. 

Sheila Garrity, 

Director, Office of Research Integrity, Office 

of the Assistant Secretary for Health. 

[FR Doc. 2023–19086 Filed 9–1–23; 8:45 am] 

BILLING CODE 4150–31–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

National Institute of Dental and 

Craniofacial Research; Amended 

Notice of Meeting 

Notice is hereby given of a change in 

the meeting of the National Advisory 

Dental and Craniofacial Research 

Council, September 12, 2023, 4:45 p.m. 

to September 13, 2023, 3:30 p.m., 

National Institutes of Health, Natcher 

Building, 45 Center Drive, Bethesda, MD 

20892, which was published in the 

Federal Register on August 17, 2023, FR 

Document 2023–17712, 88 FR 56028. 

The National Advisory Dental and 

Craniofacial Research Council Open and 

Closed Sessions meeting room has 

changed from the Natcher Building, 45 

Center Drive, Bethesda, MD 20892, and 

will now be held at the John Edward 

Porter Neuroscience Research Center 

Building, 35 Convent Drive Room 620/ 

630, Bethesda, MD 20892. Meeting 

times remain the same. The meeting is 

partially closed to the public. 

Dated: August 29, 2023. 

Melanie J. Pantoja, 

Program Analyst, Office of Federal Advisory 

Committee Policy. 

[FR Doc. 2023–19017 Filed 9–1–23; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

[Docket Number DHS–2023–0020] 

Agency Information Collection 

Activities: Generic Clearance for 

Improving Customer Experience (OMB 

Circular A–11, Section 280 

Implementation), 1601–0029 

AGENCY: Department of Homeland 

Security (DHS). 

ACTION: 30-Day notice and request for 

comments. 

SUMMARY: The Department of Homeland 

Security, DHS will submit the following 

information collection request (ICR) to 

the Office of Management and Budget 

(OMB) for review and clearance in 

accordance with the Paperwork 

Reduction Act. DHS previously 

published this information collection 

request (ICR) in the Federal Register on 

June 23, 2023, for a 60-day public 

comment period. No comments were 

received by DHS. The purpose of this 

notice is to allow additional 30-days for 

public comments. 

DATES: Comments are encouraged and 

will be accepted until October 5, 2023. 


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