1/11/2013 Page 1 of 19 

INITIAL REVIEW EXPOSURE REPORT (IRExR) 

 Chemical ID: P-13-0178 Reviewer: Bevington/BC 

 

 

Results Table: Dose, Concentration, and Days Exceeded Results Summary 

Exposure 

Scenario1 

 Water Landfill Stack Air Fugitive Air 

Drinking Water Fish Ingestion 

ADR LADD ADR LADD 7Q104 

CC = 5 

PDM 

Days 

Exceeded

LADD ADR LADD ADR LADD 

Release 

activity(ies)2; 

exposure 

calculation(s)

3 

mg/kg/day mg/kg/day mg/kg/day mg/kg/day μg/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day 

PROC 1: max 

acute eco 

--- --- --- --- 8.63E+00 --- --- --- --- --- --- 

PROC 1: 

PDM1 

--- --- --- --- 1.33E+00 0 --- --- --- --- --- 

PROC 2: max 

acute eco 

--- --- --- --- 6.38E+01 --- --- --- --- --- --- 

PROC 2: 

PDM1 

--- --- --- --- 1.42E+00 0 --- --- --- --- --- 

1 Exposure scenario titles consist of release activity followed by exposure calculation abbreviation. 

2 Release activities are from engineering report's Manufacturing (Mfg), Processing (Proc) and Use release activity 

labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location. 

3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and Probabilistic 

Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. 

 CC is the aquatic concentration of concern. 

4 This column displays concentration values for the 7Q10 streamflow, which is defined as the average daily 

streamflow of the seven consecutive days of lowest flow within a ten year period. 

Remarks: 
1/11/2013 Page 2 of 19 

Results Table: Consumer Exposure Results Summary 

 Water (DtD) Dermal Inhalation 

Drinking Water Fish Ingestion 

ADR LADD ADR LADD 7Q10 PDM 

Days 

Exceede

d 

ADR LADD ADR LADD 

Scenario mg/kg/da

y 

mg/kg/day mg/kg/day mg/kg/day μg/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day 

CEM2, 

Laundry 

detergent 

--- --- --- --- --- --- 3.46E-05 3.75E-06 1.23E-03 2.06E-04 

CEM2, 

Solid air 

freshener 

--- --- --- --- --- --- --- --- 7.22E-04 4.29E-06 

CEM2, 

Bar soap 

--- --- --- --- --- --- 5.85E-04 1.18E-05 --- --- 

CEM2, 

Perfume 

--- --- --- --- --- --- --- --- 8.24E-03 6.26E-03 

1 Down-the-Drain Module within NCEM2 model. 

2 Consumer Exposure Module within NCEM2 model.
1/11/2013 Page 3 of 19 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-13-0178 Assessor: Bevington/BC 

ENVIRONMENTAL RELEASES 

 Scenario#:1 Number of Release Sites: 1. 

 Release Activity: PROC 1: Max ADR 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 1.43 N/A N/A N/A 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 11.00 0.00/0.00 N/A N/A 

Per Site Release: 0.13 N/A/0.00 N/A N/A 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
1/11/2013 Page 4 of 19 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-13-0178 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 1 Number of Sites: 1 RELEASE ACTIVITY:PROC 1: 

Max ADR 

SIC-CODE DESCRIPTION: Soaps, Detergent, etc. Manufacture 

SIC-CODE (S): 2841-2844 EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

31.00 11. 0.13 8.97E-02 0.00 300.00 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 413.73 144.88 85.50 75.59 0.22 0.62 1.05 1.19 

ALL 10 47.35 23.64 10.39 11.73 1.89 3.79 8.63 7.65 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 5.10E-08 4.45E-07 mg/kg/day 6.55E-08 5.73E-07 mg/kg/day 

LADCpot 2.61E-06 2.28E-05 mg/L 7.84E-04 6.85E-03 mg/kg 

Acute 

ADRpot 5.17E-05 3.17E-04 mg/kg/day 1.17E-04 1.02E-03 mg/kg/day 

SIC Code Comments: 
1/11/2013 Page 5 of 19 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-13-0178 Assessor: Bevington/BC 

ENVIRONMENTAL RELEASES 

 Scenario#:2 Number of Release Sites: 1. 

 Release Activity: PROC 1: PDM1 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 0.40 N/A N/A N/A 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 20.00 0.00/0.00 N/A N/A 

Per Site Release: 2.00E-02 N/A/0.00 N/A N/A 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
1/11/2013 Page 6 of 19 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-13-0178 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 2 Number of Sites: 1 RELEASE ACTIVITY:PROC 1: 

PDM1 

SIC-CODE DESCRIPTION: Soaps, Detergent, etc. Manufacture 

SIC-CODE (S): 2841-2844 EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

31.00 20. 0.02 1.38E-02 0.00 300.00 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 413.73 144.88 85.50 75.59 3.34E-02 9.53E-02 0.16 0.18 

ALL 10 47.35 23.64 10.39 11.73 0.29 0.58 1.33 1.18 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 1.43E-08 1.25E-07 mg/kg/day 1.83E-08 1.60E-07 mg/kg/day 

LADCpot 7.31E-07 6.39E-06 mg/L 2.19E-04 1.92E-03 mg/kg 

Acute 

ADRpot 7.96E-06 4.88E-05 mg/kg/day 1.80E-05 1.57E-04 mg/kg/day 

SIC Code Comments: 
1/11/2013 Page 7 of 19 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-13-0178 

SIC CODE EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 2 RELEASE ACTIVITY: PROC 1: PDM1 

SIC CODE DESCRIPTION: Soaps, Detergent, etc. Manufacture 

ASSOCIATED SIC CODES: 2841-2844 

SIC CODE RESULTS 

COC (μg/L) 

Percent of 

Year COC 

Exceeded 

Number of 

Days COC 

Exceeded 

Release 

days/year 

Loading 

(kg/site/day) 

Waste Water 

Treatment (%) 

High/Avg 

Analysis 

5.00 0 0 20.00 2.00E-02 31.00 High 
1/11/2013 Page 8 of 19 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-13-0178 Assessor: Bevington/BC 

ENVIRONMENTAL RELEASES 

 Scenario#:3 Number of Release Sites: 1. 

 Release Activity: PROC 2: Max ADR 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 5.77 N/A N/A N/A 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 6.00 0.00/0.00 N/A N/A 

Per Site Release: 0.96 N/A/0.00 N/A N/A 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
1/11/2013 Page 9 of 19 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-13-0178 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 3 Number of Sites: 1 RELEASE ACTIVITY:PROC 2: 

Max ADR 

SIC-CODE DESCRIPTION: Soaps, Detergent, etc. Manufacture 

SIC-CODE (S): 2841-2844 EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

31.00 6. 0.961 0.66 0.00 300.00 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 413.73 144.88 85.50 75.59 1.60 4.58 7.76 8.77 

ALL 10 47.35 23.64 10.39 11.73 14.00 28.05 63.82 56.53 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 2.05E-07 1.80E-06 mg/kg/day 2.64E-07 2.31E-06 mg/kg/day 

LADCpot 1.05E-05 9.21E-05 mg/L 3.16E-03 2.76E-02 mg/kg 

Acute 

ADRpot 3.82E-04 2.34E-03 mg/kg/day 8.64E-04 7.55E-03 mg/kg/day 

SIC Code Comments: 
1/11/2013 Page 10 of 19 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-13-0178 Assessor: Bevington/BC 

ENVIRONMENTAL RELEASES 

 Scenario#:4 Number of Release Sites: 1. 

 Release Activity: PROC 2: PDM1 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 5.35 N/A N/A N/A 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 250.00 0.00/0.00 N/A N/A 

Per Site Release: 2.14E-02 N/A/0.00 N/A N/A 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
1/11/2013 Page 11 of 19 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-13-0178 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 4 Number of Sites: 1 RELEASE ACTIVITY:PROC 2: 

PDM1 

SIC-CODE DESCRIPTION: Soaps, Detergent, etc. Manufacture 

SIC-CODE (S): 2841-2844 EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

31.00 250. 0.0214 1.48E-02 0.00 300.00 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 413.73 144.88 85.50 75.59 3.57E-02 0.10 0.17 0.20 

ALL 10 47.35 23.64 10.39 11.73 0.31 0.62 1.42 1.26 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 1.91E-07 1.67E-06 mg/kg/day 2.45E-07 2.14E-06 mg/kg/day 

LADCpot 9.78E-06 8.54E-05 mg/L 2.93E-03 2.56E-02 mg/kg 

Acute 

ADRpot 8.52E-06 5.22E-05 mg/kg/day 1.92E-05 1.68E-04 mg/kg/day 

SIC Code Comments: 
1/11/2013 Page 12 of 19 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-13-0178 

SIC CODE EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 4 RELEASE ACTIVITY: PROC 2: PDM1 

SIC CODE DESCRIPTION: Soaps, Detergent, etc. Manufacture 

ASSOCIATED SIC CODES: 2841-2844 

SIC CODE RESULTS 

COC (μg/L) 

Percent of 

Year COC 

Exceeded 

Number of 

Days COC 

Exceeded 

Release 

days/year 

Loading 

(kg/site/day) 

Waste Water 

Treatment (%) 

High/Avg 

Analysis 

5.00 0 0 250.00 2.14E-02 31.00 High 
1/11/2013 Page 13 of 19 

CEM Inputs ID Number: P-13-0178,5 

Product: unknown Chemical Name: P-13-0178 

Scenario: Laundry Detergent Population: Adult 

Molecular Weight (g/mole): 198 Vapor Pressure (torr) 0.096 

Consumer Product Weight Fraction - 

Central Tendency (unitless): 

0.0002 Consumer Product Weight Fraction - HighEnd (unitless): 0.0002 

Inhalation Inputs 

Frequency of Use (chronic) (events/yr): 312 Exposure Duration (chronic) (years): 57 

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1 

Mass of Product Used per Event - Central 

Tendency (g): 

200 Mass of Product Used per Event - High-End 

(g): 

400 

Inhalation Rate During Use (m3/hr): 1.1 Duration of Event - Central Tendency 

(hours/event): 

0.333 

Inhalation Rate After Use (m3/hr): 0.55 Duration of Event - High-End 

(hours/event): 

0.667 

Zone 1 Volume (m3): 20 Whole House Volume (m3): 369 

Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 71.8 

 

Activity Patterns (Note: 1=Bedroom 2= Kitchen 3=Bathroom 4=Living Room 

 5=Utility Room 6=Car 7=Out) 

User: 1 1 1 1 1 1 1 2 3 5 5 4 2 4 6 7 4 2 2 7 4 4 4 1 

Non-User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1 

Hour: 0 6 12 18 

Start Time: 9 Room of Use: 5. Utility Room 

Dermal Inputs 

Frequency of Use (chronic) (events/yr): 52 SA/BW (cm2/kg): 15.6 

Frequency of Use (acute) (events/day): 1 

 Exposure Duration (chronic) (years): 57 

Amount Retained / Absorbed to Skin 

(g/cm2-event): 

1.11e-05 Exposure Duration (acute) (days): 1 

 

Averaging Time (chronic) (days): 2.74e+04 Averaging Time (acute) (days) : 1 

 

 
1/11/2013 Page 14 of 19 

CEM Inhalation Exposure Estimates 

 ID Number: P-13-0178,5 

 Scenario: Laundry Detergent (Machine Washing) Population: Adult 

 Exposure Duration (years) chronic: 57 Exposure Duration (days) acute: 1 

 

Exposure Units Result AT (days) 

 Chronic Cancer 

 LADDpot (mg/kg-day) 2.06e-04 2.74e+04 

 LADCpot (mg/m3) 6.40e-04 2.74e+04 

 Acute 

 ADRpot (mg/kg-day) 1.23e-03 1 

 Cppot (mg/m3) 1.01e-01 NA 

 LADD - Lifetime Average Daily Dose (mg/kg-day) LADC - Lifetime Average Daily Concentration (mg/m3) 

 ADR - Acute Dose Rate (mg/kg-day) Cp - Peak Concentration (mg/m3) 

 

Note: 75 years = 2.738e+04 days pot - potential dose 

Note: The general Agency guidance for assessing short-term, infrequent events (for most chemicals, an exposure of less than 24 

hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than 

as chronic exposure. (Methods for Exposure-Response Analysis for Acute Inhalation Exposure to Chemicals (External 

Review Draft). EPA/600/R-98/051. April 1998)
1/11/2013 Page 15 of 19 

CEM Dermal Exposure Estimates 

 ID Number: P-13-0178,5 

 Scenario: Laundry Detergent (Hand 

Washing) 

 Population: Adult 

 Exposure Duration (chronic) (years): 57 Exposure Duration (acute) (days): 1 

 

Exposure Units Result AT (days) 

Chronic Cancer 

 LADDpot (mg/kg-day) 3.75e-06 2.74e+04 

Acute 

 ADRpot (mg/kg-day) 3.46e-05 1 

 LADD - Lifetime Average Daily Dose (mg/kg-day) 

 ADR - Acute Dose Rate (mg/kg-day) 

 
1/11/2013 Page 16 of 19 

CEM Inputs ID Number: P-13-0178,6 

Product: unknown Chemical Name: P-13-0178 

Scenario: Solid Air Freshener Population: Adult 

Molecular Weight (g/mole): 198 Vapor Pressure (torr): 0.096 

Consumer Product Weight Fraction - 

Central Tendency (unitless): 

0.0002 Consumer Product Weight Fraction - 

High-End (unitless): 

0.0002 

Inhalation Inputs 

Frequency of Use (chronic) (events/yr): 6.14 Exposure Duration (chronic) (years): 57 

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1 

Mass of Product Used per Event - Central 

Tendency (g): 

52.7 Mass of Product Used per Event - 

High-End (g): 

113.4 

Inhalation Rate During Use (m3/hr): 1.1 Duration of Event - Central Tendency 

(hours/event): 

720 

Inhalation Rate After Use (m3/hr): 0.55 Duration of Event - High-End 

(hours/event): 

2160 

Zone 1 Volume (m3): 9 Whole House Volume (m3): 369 

Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 71.8 

 

Activity Patterns 

User: 1 1 1 1 1 1 1 2 3 1 5 4 2 4 6 7 4 2 2 7 4 4 4 1 

Non-User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1 

Hour:0 6 12 18 

Start Time: 12 Room of Use: 3. Bathroom 

Dermal Inputs 

There are no Dermal inputs for this scenario. 

Averaging Time (chronic) (days): 2.74e+04 Averaging time (acute) (days) : 1 

 
1/11/2013 Page 17 of 19 

CEM Inhalation Exposure Estimates 

 ID Number: P-13-0178,6 

 Scenario: Solid Air Freshener Population: Adult 

 Exposure Duration (years) chronic: 57 Exposure Duration (days) acute: 1 

 

Exposure Units Result AT (days) 

 Chronic Cancer 

 LADDpot (mg/kg-day) 4.29e-06 2.74e+04 

 LADCpot (mg/m3) 2.33e-05 2.74e+04 

 Acute 

 ADRpot (mg/kg-day) 7.22e-04 1 

 Cppot (mg/m3) 1.46e-02 NA 

 LADD - Lifetime Average Daily Dose(mg/kg-day) LADC - Lifetime Average Daily Concentration (mg/m3) 

 ADR - Acute Dose Rate (mg/kg-day) Cp - Peak Concentration (mg/m3) 

 

Note: 75 years = 2.738e+04 days pot - potential dose 

Note: The general Agency guidance for assessing short-term, infrequent events (for most chemicals, an exposure of less than 24 

hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than 

as chronic exposure. (Methods for Exposure-Response Analysis for Acute Inhalation Exposure to Chemicals (External 

Review Draft). EPA/600/R-98/051. April 1998 
1/11/2013 Page 18 of 19 

CEM Inputs ID Number: P-13-0178,7 

Product: unknown Chemical Name: P-13-0178 

Scenario: Bar Soap Population: Adult 

Molecular Weight (g/mole): 198 

Consumer Product Weight Fraction - 

Central Tendency (unitless): 

0.0002 Consumer Product Weight Fraction - 

High-End (unitless): 

0.0002 

Inhalation Inputs 

There are no Inhalation inputs for this scenario. 

Activity Patterns 

There are no Activity Patterns for this scenario. 

Dermal Inputs 

Frequency of Use - body (chronic) 

(events/yr): 

1 SA/BW - body (cm2/kg): 286 

Frequency of Use - body (acute) 

(events/day): 

1 SA/BW - Hands (cm2/kg): 15.6 

Frequency of Use - Hands (chronic) 

(events/yr): 

133 Exposure Duration (years) chronic: 74 

Frequency of Use - Hands (acute) 

(events/day): 

2 Exposure Duration (days) acute: 1 

Amount Retained/Absorbed to Skin 

(g/cm2-event): 

9.22e-06 

 

 

 

Averaging Time (chronic) (days): 2.74e+04 Averaging Time (acute) (days) : 1 

 

 
1/11/2013 Page 19 of 19 

CEM Dermal Exposure Estimates 

 ID Number: P-13-0178,7 

 Scenario: Bar Soap Population: Adult 

 Exposure Duration (years) chronic: 74 Exposure Duration (days) acute: 1 

 

Exposure Units Result AT (days) 

 Chronic Cancer 

 LADDpot (mg/kg-day) 1.18e-05 2.74e+04 

Acute 

 ADRpot (mg/kg-day) 5.85e-04 1 

 LADD - Lifetime Average Daily Dose (mg/kg-day) 

 ADR - Acute Dose Rate (mg/kg-day) 

 

Note: 75 years = 2.738e+04 days pot - potential dose 

Note: The general Agency guidance for assessing short-term, infrequent events (for most chemicals, an exposure of 

less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute 

exposures rather than as chronic exposure. (Methods for Exposure-Response Analysis for Acute Inhalation 

Exposure to Chemicals (External Review Draft). EPA/600/R-98/051. April 1998)