## 1 OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION 

### UNITED ST **AT ES ENVIRONMENT** **AL PROTECTION A** **GENCY**

**WA SHINGTON D.C., 20460** 



## PC Code : 046679 DP Barcode: D409837

415146 Date: September 18 , 2013 MEMORANDUM SUBJECT: Fenamidone : Drinking Water Assessment for the Proposed New Use s on Potato

Seed , Ginseng, Bulb Onion (Crop Subgroup 3 - 07A), Green Onion (Crop Subgroup 3 - 07B) , and Succulent Beans for Reason ® 

## 500 SC (44.4% fenamidone) (EPA Reg. No. 264 - 695) and Fenamidone Technical EPA Reg. No. 264 - 693) CAS Name: ( 5 S

) - 3,5 - dihydro - 5 - methyl - 2 - (methyl thio) - 5 -phenyl - 3 - (phenyl amino) - 4H

- imidazol - 4 - one CAS Reg. No.: 161326 - 34 - 7 FROM: James K. Wolf, Ph.D . , Environmental S cientist

Environmental Risk Branch III Environmental Fate and Effects Division (7507P) THROUGH: James A Hetrick , Ph.D., Senior Scientist

Rosanna Louie - Juzwiak, RAPL Dana S. Spatz., Branch Chief Environmental Risk Branch III Environmental Fate and Effects Division (7507P) TO: Id eliz Encarnacion, Ph.D.

Michael Metzger , Ph.D., Branch Chief Risk Assessment Branch 7 Health Effects Division (7509P) Barbara Madden, RM 05 RIMUERB Registration Divison (7505P)

## 2

The registrant (Bayer Corporation) is seeking to amend the fenamidone label to allow for the potato seed treatment use to replace one of the registered foliar applications for potatoes and the IR- 4 is requesting the addition of ginseng, succulent b ean, and the expansion of bulb v egetables use s ( Crop Subgroups 3 - 07A and 3 - 07B , Table 1 ) to the fenamidone label. The maximum annual fenamidone application rate remains 0.8 0 lb a.i./A per season [ year] for potatoes. Fenamidone is registered for use as a broad spectrum foliar fungicide for control of certain pathogenic fungal diseases in a variety of crops including potatoes and other tuberous and corm vegetables, tomatoes, onions and other bulb vegetables, lettuce, le af y vegetables, Brassica vegetables, tobacco, fruiting vegetables, carrots, cucurbit crops, and treatment of cotton and sunflower seeds as well as in - furrow application before planting of the seeds. This memo summarizes the Tier II PRZM/EXAM S , PRZM - GW and Tier I SCI - GROW estimated drinking water concentrations (EDWCs) of fenamidone plus its degradation products ( i.e., total fenamidone residues of concern or total toxic residues ) in surface water and in groundwater for the proposed new us es and label amendm ents . The metabolites/degradation products , RPA - 412636, RPA - 412 7 08 , RPA - 411639, RPA - 413255, RPA - 409446, and RP 410995 , included in the drinking water total fenamidone residues of concern 1 

## are liste d in Appendix 1 Table 1. The degradation products tend to be more persistent and exhibit greater mobility than parent fenamidone , suggesting the increased potential for degradates leaching to groundwater . The drinking water EDWCs recommended for use in the human health dietary risk assessment are those estimated for groundwater. The highest daily total fenamidone residue concentration in shallow groundwater estimated by PRZM - GW is 207μg/L and the average concentration after breakthrough was 139 μg/L (Table 8 ) for the Central San ds Region of Wisconsin from 30 years of continuous use . These estimates represent potential exposure to private drinking water well in a highl y vulnerable pesticide use area where numerous pesticide residues have been detected in groundwater. The surface water EDWCs estimated by PRZM/EXAMS are 49.19 μg/L and 12.96 μg/L , for the 1 - in - 10 year daily

peak and annual mean total fenamidone residues concentration, respectivel y . The 30 - year annual mean is 8.21 μg/L (Table 7). Previously , total fenamidone residues 2 

## in surface source drinking water (PRZM/EXAM S ) for the 1 - in - 10 year daily

peak and annual mean concentration were 41.66 μg/L and 11.88 μg/L , respectivel y , and the 30 - ye ar annual mean concentration 5.99 μg/L . The estimated total fenamidone residue concentration in shallow groundwater was with SCI - GROW was 178 μg/L (Table 9 ) . **Use Characterization** Fenamidone (REASON 500 SC Fungicide) is the active ingredient (a . i . ), in the broad - spectrum foliar fungicide that is a

pplied by ground, chemigation, and/or aerial equipment, and seed

1 http://www.gpo.gov/fdsys/pkg/FR- 2009 - 07 - 15/pdf/E9 - 16817.pdf 2 USEPA, 2007. Drinking Water Assessment for New Uses. (D332878, D316085, D316083; May 14, 2007).

## 3

treatment (sunflower and tobacco) . Currentl y, the maximum application rate is 0.267 lb a . i . /A with a maximum seasonal [ annual ] rate of 0.80 lb a.i./A , with a minimum 5 - day reapplication interval . A p revious drinking water assessment wa s c onducted for this maximum use rate. IR- 4 has proposed that fenamidone be applied at rates up to 0.267 lb a.i./A , with a 5 day minimum reapplication interval , and a maximum seasonal rate not to exceed 0.80 lb a.i./A for ginseng and succulent beans (T able 1) . For bulb vegetables the maximum application rate for fenamidone is 0.178 lb a.i./A , seasonal maximum rate of 0.71 lb a.i./A per season with a minimum reapplication interval of 5 days. For these uses, the applicati on methods remain ground and aerial spray

and chemigation. The registrant (Bayer Corporation) is also seeking to amend the fenamidone label 3 

## to allow for the potato seed treatment (Table 1) use to replace one of the registered foliar applications for potatoes. The proposed maximum annual fenamidone application rate remains 0.8 0 lb a.i./A per season for potatoes. Application rates and frequency of application for the proposed amended uses are shown in Table 1 . This assessment assumes that 1 season is sy

nony mous with yearl y, which is one crop per ye ar. **T able 1. Fenam** **idone use and application inform ation**  **obtained from the proposed new uses label and the**  **current potato rate for Reason**  **®** 

### 500 SC (44.4% fenamidone) (EPA Reg **. No**  **. 264**  **- 695).** 

**Use Max. Single App.**  **Rate (lb a**  **. i**  **. /** **A )**  **# of App./**

**Season Seasonal Max.** 

**Rate (lb a.i./A** **) Minim** **um App.** 

**Interval (days) Proposed new uses and label am**  **endment by the IR4 REASON**  **®** 

### 500 SC Fungicide

**EPA Reg. No. 264 -**  **695 (44.4% ai; 4.13 lb ai/gallon)** Bean, Succulent

Bean, lima Bean, snap 0.267 NS (3) a 

### 0.80 7 Ginseng 0.267 NS (3) a 

### 0.80 14 Expansion to Full Crop Group s Onion bulb, Sub - group 3 - 07A b 

### 0.178 NS (4) a 

### 0.71 5 Onion, green, Sub - group 3 - 07B b 

### Proposed am **endment by Bayer CropScience REASON**  **®** 

### 500 SC Fungicide EPA Reg. No. 264 **- 695**  **(44.4% ai; 4.13 lbs ai/gallon)** Potato Seed Treatmentc 

### 0.237 d 

### (0.15 fl oz/100 lb seed potato) See f 

### 0.80 e 

### 5 f 

### Potato Foliar Application **Current ly**  **Approved Label (EPA Reg. No. 264**  **- 695:**  **as of 10/27/2011)**  Potatoes 0.267 NS (3) a 

### 0.80 e 

### 5 a NS - is not specified (number = maximum growing season rate/maxi mum rate ) b **Bulb vegetables** : Chive, fresh leaves; Chinese, fresh leaves; daylily, bulb; elegans hosta; fritillaria, bulb; fritillaria, leaves; garlic, bulb; garlic, great- headed, bulb; garlic, serpent, bulb; kurrat; lady’s leek; leek ; leek, wild; lily, bulb; onion, Beltsville bunching; onion, bulb; onion, Chinese, bulb; onion, fresh, green; onion, macrostem; onion, pearl; onion, potato, bulb; onion, tree, tops; onion, Welsh, tops; shallot, bulbs; shallot, fresh leaves; cultivars, varieties, and/or hybrids of these. c **Potato seed -**  **piec e treatment**  (Use rate = 0.15 fl oz per 100 lbs of seed pieces). d 4.13 lb ai/gallon *1gallon/128 fl oz = 0.03227 lb ai/fl oz 0.15 fl oz/100 lb psp (potato seed piece) *0.03227 lb ai/fl oz = 0.004842 lb ai/100 lb psp Planting rate 1000 to 4900 lb psp/ac; 0.004842 lb ai/100 lb psp * 4900 lb psp/ac = 0.237 lb a.i./A ; could be as high as 0.245 lb a.i./A (MRID 4897701) 3 EP A Reg # Fenamidone Technical 264 - 693 and Reason ® 500 SC 264 - 695) .

## 4 e Maximum amount of fenamidone per season (year) is 0.80 lb a.i./A . f Additional fenamidone may still applied foliarly, at maximum rate of 0.267 lb a.i./A , with a annual rate not to exceed 0.80 lb a.i./A .

## 5

**Potato Seed Pieces –**  **Seed Treatment** The proposed potato seed treatment rate is 0.15 fluid ounces per 100 pounds (cwt) of seed pieces. Potato seed planting rates vary from 1 , 800 to 4 , 900 lb potato seed pieces per acre according to information submitted by the registrant (Petition to Establish a Seed Piece Treatment Use with Fenamidone on Potatoes , MRID 48977101). BEAD 4 

## reports seed potato rates ranging from 2,100 to 2,700 lb potato seed per acre. Depending upon the seeding rate for the potato pieces, the fenamidone application rate could range from about 0.10 to 0.245 lb a.i./A (Table 2 ). This assessment uses the maximum rate of 0.245 lb a.i./A as proposed b y Baye r CropScience as a conservative maximum application rate for this assessment (MRID 48977101) . **Table 2**  **. Conversion of Fenamidone Rate to**  **Potato Seed Piece per 100 lbs to Application Rate on a Pounds ai per acre b**  **asis.** fl oz/100 lb psp a 

### lb ai/fl ozb 

### lb ai/100 lb psp lb psp/ac c 

### lb a.i./A 0.15 0.03227 0.00484 2000 0. 09 7 0.15 0.03227 0.00484 3000 0.145 0.15 0.03227 0.00484 4000 0.194 0.15 0.03227 0.00484 4900 0.237 d a psp = potato seed piece. b Reason ® 500 SC 264 - 695 density = 4.13 lb ai/gallon ; 1 gallon = 128 fl oz; 0.03227 = 4.13/128. c MRID 48977101 d Difference between 0.237 and 0.245 lb a.i./A is due rounding during unit conversion calculations . 

## Fenamidone Chemistry, **Environmental Fate and Transport**  **Characterization** Fenamidone is member of the chemical family of fungicides, the imidazolinones (Figure 1) . Fenamidone is the S

- enantiomer of the racemic mixture A5 - Methyl - 2 - methylthio - 5 -phenyl - 3 - phenylamino - 3,5 - dihydroamino - 4 - one (IUPAC). The S - enantiomer is claimed to be the fungicide active enantiomer. The amount of S - enantiomer in the active ingredient is greater than 98%. Reason ® 

## 500 SC is a soluble concentrate formulation containing 44.4% fenamidone as the active ingredient , contain ing 4.13 lbs of fenamidone per gallon of product.

4 

### Becker, J. and S. Ratnayake. 2011. Acres Planted per Day and Seeding Rates of Crops Grown in the United States. Biologic al and Economic Analysis Division (BEAD), USEPA. March 11, 2011.

## 6 Fenamidone Structure Chemical Abstracts Registry Number (CAS) : 161326 - 34 - 7 Em pirical Formula: C 17 

### H 17

### N 3 

### OS Chemical Abstract Registry Name s : ( S) - 3,5 - dihydro - 5 - methyl - 2 - methylthio - 5 -phenyl - 3 - phenylamino - 4H - imidazole - 4 - one; (+) - (4 S ) - 4 - Methyl - 2 - methylthio - 4 -phenyl - (1H) - 1 -phenylamino - 2 - imidazolin - 5 - one (5 S ) - 3,5 - dihydro - 5 - methyl - 2 - (methylthio) - 5 -phenyl - 3 - (phenylamino) - 4H - imidazol - 4 - one IUPAC Name

s : (+) - 4 - me thyl - 2 - methylthio - 4 - phenyl - 1 -phenylaminoimidazol - 1H - 5 - one; (S ) - 5 - Methyl - 2 - methylthio - 5 - phenyl - 3 -phenylamino - 3,5 - dihy roimidazol - 4 - one (S ) - 1 - anilino - 4 - methyl - 2 - me thylthio - 4 -phenylimidazolin- 5 - one USEPA/OPP Chemical Database: Imidazol - 4 - one,3,5 - dihydro - 5 - methyl - 2 - (methylthio) - 5 -phenyl - 3 - (phenylamino) - , (5S) - ) Other Names: 4H - Imidazol - 4 - one, 3,5 - dihydro - 5 - me thyl - 2 - (methylthio) - 5 - phenyl - 3 - (phenylamino) - , (5S) - 4H - Imidazol - 4 - one, 3,5 - dihydro - 5 - me thyl - 2 - (methylthio) - 5 - phenyl - 3 - (phenylamino) - , (S) - S - 5 - Methyl - 2 - methylthio - 5 -phenyl - 3 -phenylamino - 3,5 - dihydro - 4H - imidazol - 4 - one **Figure 1 Chemical Structure, CAS No., Empirical Formula, and Chemicals for Fenamidone.**  

## Environmental Fate S **ummary** The environmental fate for fenamidone is discussed in detailed in the new chemical assessment USEPA (2002 5 

## ) and is summarized below . The major route of degradation for fenamidone in the environment is biotransformation under aerobic conditions. Fenamidone is moderately mobile and appears to degrade faster in aerobic soils (half - lives 5 to 8 days) than in aerobic water - sediment systems (half - lives 67 to 128 days). Fenamidone is very

stable in anaerobic sediments (half - lives > 1,000 days). In the e nvironmental pH range of 5 to 9, fenamidone is stable towards abiotic hy drolysis. Although direct photolysis occurred rapidly

in laboratory

studies (half

- liv e s 5 to 6 days) direct photol ysis in natural water would be only

significant in clear, shallo w water. The role of ind irect photolysis is not known.

5 USEPA , 2002. New Chemical, Environmental and Ecological Risk Assessment for Fenamidone and its end -use product Reason 500 SC. (D282668, October 2, 2002)

## 7

Fenamidone poses low concern for volatilization from soil or water and is unlikely to bioaccumulate in fish. The major, terminal metabolite is the cleavage product (S ) - Methyl - 5 -phenylimidazolidine - 2,4 - dione (RPA - 412636). It can form in aerobic water, aerobic soils , and water - sediment systems , and is a persistent chemical species (aerobic soil half - lives as long as 462 days). In addition, RPA - 412636 and its immediate precursor RPA - 417208 (cleavage product) are very mobile in soil and can leach to groundwater or be transported to surface water b y runoff or spray drift , where they p redominantly partition into the water column. The degradates of concern [and studies where they

are formed] are RPA - 412636 , RPA - 411639, RPA - 413255 [ aerobic soil metabolism, aerobic water- sediment s ys tems, and terrestrial field dissipation] , RPA - 412708 6 

## [ hydrolysis @ pH 4; 9 and photolysis ], and RPA - 409446 and RP - 410995 [aerobic soil metabolism]. The summary of degradation p rocesses are found in Appendix 1, Table 1, and the structures are shown in Appendix 1, Table 2. Hydrolysis wa s determined not a major degradation pathway , but it is faster at pHs below 5 and above 9 (New Chemical Review, D282668, October 2, 2002) . Assuming pseudo first order kinetics the half

- lives of 41.8 days , 223 days, 407 days , and 27.2 days at pH 4, 5, 7, and 9, respectivel y, were estimated (MRID 453858 - 29). EFED has observed that PRZM - GW is more sensitive to pH, even with long half - lives , compared to surface water (PRZM/EXAMS) . The f enamidone degradation products exhibit properties in common with other pesticide residue s that are known to dissolve in runoff water to reach surface water bo dies and leach to groundwater. Furthermore, fenamidone residues may also reach surface water bodies via erosion or through spray

drift. **Residues of Concern** Throughout this document, fenamidone and its metabolites/ degradates (Appendix 1 Table 1) are named b y the company code assigne d onl y to the S - enantiomer . The company code for fenamidone is RPA 407213. On May 25, 2004 7 

## , the Metabolism Assessment Review Committee (MARC) recommended that, besides parent fenamidone, the additional metabolites/degradation products RPA - 412636, RPA - 412 7 08 , RPA - 411639, RPA - 413255, RPA - 409446, and RP 410995 [ i.e., total fenamidone residues] should be included in the drinking water assessment (Appendix 1 Table s 1 and 2 ). **Drinking Water Modeling** EFED exposure models were used to estimate the drinking water exposure concentrations for use in the dietary

risk assessment of fenamidone. The estimated drinking water concentrations ( EDWC ) for fenamidone and its residues (total fenamidone residues , TTR) of concern in surface water (Table 7) were estimated using Tier II models ( linked PRZM and EXAMS by PE5 ).

6 

### Some documents have listed this degradate as RPA - 412108. 7 

### TXR No. 0052287

## 8

Tier I and II groundwater EDWCs for fenamidone residues for the proposed new uses were derived with PRZM - GW (Pesticide Root Zone Model for Groundwater, version 1.0, August 31, 2012 ), using the GW - GUI(Graphical User Interface, version 1.0, August 31, 2012 ). PRZM - GW is a one - dimensional, finite - difference model that estimates the concentrations of pesticides in groundwater. It accounts for pesticide fate in the crop root zone by simul ating pesticide transport and degradation through the soil profile after a pesticide is applied to an agricultural field. PRZM - GW permits the assessment of multiple years of pesticide application (up to 30 years) on a single site. Six standard scenarios, e ach representing a different region known to be vulnerable to groundwater contaminations, are available for use with PRZM - GW for risk assessment purposes. In the PRZM - GW simulations, each of these standard scenarios was used. PRZM - GW output values represent pesticide concentrations in a vulnerable groundwater supply that is located directly

beneath a rural agricultural field. Note that, unlike in surface water modeling, PCAs are not used with PRZM - GW per EFED guidance. Estimates from PRZM - GW are presented in Table 8. For comparison purposes, EDWCs were also calculated (Table 9) using the Screening Concentration in Ground Water model (SCI - GROW v2.3, compiled 08/08/03). SCI - GROW was developed b y fitting a linear model to ground water concentrations with the Relative Index of Leaching Potential (RILP) as the independent variable. Ground water concentrations were taken from 90 - day

average high concentrations from Prospective Ground Water studies. The RILP is a function of aerobic soil metabolism and the soi l - water partition coefficient. There is no PCA adjustment for SCI - GROW. The output of SCI - GROW represents the concentrations of fenamidone total residues that might be expected in shallow unconfined aquifers under sandy soils. The input parameters were selected from the physical/chemical properties and environmental fate data submitted b y the registrant to support registration of fenamidone. Input parameters were selected in accordance with US EPA - OPP EFED water model parameter selection guidelines, Gui dance for Selecting Input Parameters in Modeling the Environmental Fate and Transport of Pesticides 8 

## and PRZM - GW Input Parameter Guidance 9



## . Detailed information about the models, selection of input parameters and scenarios can be obtained from http://www.epa.gov/oppefed1/models/water/index.htm The drinking water exposure assessment for total fenamidone residues is based on modeling. Modeling for individual residues was not conducted due to lack of environmental fate data. Monitoring data were not available to assess total fenamidone residue concentrations in surface and ground source waters. Because the modeling approach requires use of the cumulative residue degradation half

- lives as well a s the lowest soil:water partitioning coefficient for fenamidone, the estimated concentration in drinking water are expected to be conservative.

8 

### Parameters are selected as per Guidance for Selecting Input Parameters in Modeling the Environmental Fate and Transport of Pesticides; Version 2.1, October 22, 2009. 9 Baris, R.; Barrett, M.; Bohaty, R.; Echeverria, M.; Kennedy, I.; Malis, G.; Wolf, J.; Young, D. PRZM - GW Input Parameter Guidance ; Health Canada, U.S. Environmental Protection Agency, October 12, 2012

## 9

**Fenamidone Total Residues Modeling Input Parameters** The modeling of total fenamidone residues , or total toxic residues (TTR) , requires recalculation of cumulative fenamidone residue half - lives from laboratory

degradation studies. Recalculation of aerobic soil metabolism half - lives was conducted ( see USEPA, 2007 10 

## ) using the summed concentration (expressed as % of applied parent) for parent fenamidone and its degradation products **(**RPA - 412636, RPA - 412 7 08 , RPA - 411639, RPA - 413255, RPA - 409446, RP A 410995) 6, 11



## . The mobility

of total fenamidone residues (TTR) is based on the compound with the lowest soil:water partitioning coefficient. This approach was used to provide a conservative assessment of mobility

for the fenamidone residues. Batch equilibrium partition coefficients of fenamidone and its degradation products are shown in Table 3 . The batch equilibrium p artition coefficient for RPA - 412636 was used to represent mobility of total fenamidone residues. **Table 3**  **: Batch Equilibrium Coefficients for Fenam idone and Its Degradation Products**  **Company Code Average K** **oc** 

### (m**L/g oc** 

### ) **Data Source** Fenamidone 368 MRID 453858 23 **RPA -** **412636 26**  **MRID 45385824** RPA - 412 7 08 a 

### 31 MRID 45385825 RPA - 411639 611 MRID 45385826 RPA - 413255 458 MRID 45385827 RPA - 409446 No Data RP A - 410995 No Data a 

## May be referred to RPA - 412108 in some EFED documents. The environmental fate data used for model inputs (Table 4 ) are the same as used in the previous drinking water assessment (USEPA, 2007) and follow ed EFED input guidance . **Table 4**  **. PRZ M/EXAMS**  **and PRZ M**  **- GW**  **Input Param eters for Total**  **Toxic Fenam** **idone Residues** 

**Model Param eter**  **Value Reference**  Molecular Weight (g/moles) 311.4 Calculated (MRID 45385704) Henry’s Law Constant (atm - m3/mol) 1.37E - 10 Estimated used value for parent Vapor Pressure (torr) 2.6E - 9 Product Chemistry Data used value for parent Solubility (mg/L) 7.8 Product Chemistry Data used value for parent Koc 

### (L/mg - OC) a 

### 26 a 

### MRID 45385824 Photolysis Half

- life (days) 5.4 MRID 45385830, 45385831 Hydrolysis @ pH 7 (days) a 

### 407 a 

### MRID 45385829 Aerobic Soil Half

- life (days) ( for TTR) a 

### Stable a 

### MRID 45385819

10 USEPA, 2007. Drinking Water Assessment for New Uses. (D332878, D316085, D316083; May 14, 2007). 11 http://www.gpo.gov/fdsys/pkg/FR- 2009 - 07 - 15/pdf/E9 - 16817.pdf

## 10 **Model Param eter**  **Value Reference**  Aerobic Aquatic Half

- life (days) 137.78 MRID 45385821 , 45385822 Anaerobic Aquatic Half

- life (days) 1386.29 MRID 4540003 a Inputs considered in PRZM - GW . . 

## Previous Drinking Water Assessments A drinking w ater a ssessment [ January 28, 2004 (DP D 294195, D 292900)] was previously conducte d for uses on l ettuce, p otato, s weet p otato , tomato, bulb v egetables, and cucurbits . This assessment considered fenamidone and its major metabolite RPA - 412636. On May 25, 2004 12 

## the Metabolism Assessment Review Committee (MARC) recommended that, bes ides parent fenamidone, additional metabolites should be included in the drinking water assessment (Appendix 1 Table 1). A follow - up drinking water assessment for total fenamidone residues was conducted in 2007 [ USEPA, May 14, 2007 ] to include the additional metabolites/degradates using the total toxic residues (TTR) . Total fenamidone residues ( or TTR) in surface source drinking water for were 41.66 μg/L and 11.88 μg/L , the 1 - in - 10 year dail y peak and annual mean concentration , respectively , and 5.9 9 μg/L the 30 - ye ar annual mean concentration s . The total fenamidone residue concentration in shallow groundwater was estimated with SCI - GROW to be 178 μg/L . The environmental fate values and the maximum fenamidone application rates used for modeling were the same for this assessment and the previous assessment. Since the application rates are the same, the increase in EDWCs for surface water is for the proposed succulent bean use and is likely due to differences in the scenarios, pesticide application dat es, and the occurrence of rainfall events rather than being related to a specific crop. Additionall y, the maximum default PCA increased slightly

from 0.87 to 0.91 in the recent update (USEPA, 2012 13 

## ) . For groundwater the PRZM - GW model considers 30 years of use whereas SCI - GROW only considers one ye ar of pesticide use and did not allow for spatial or temporal differences. **Surface Water** The PRZM scenarios used are summarized in Table 5 . The application rates, reapplication intervals, and date first application are also given . The proposed modification to the potato label w ould allow for the application of fenamidone as a potato seed treatment in addition to the foliar applications. A non - standard modeling approach was used to assess this seed treatment use on potato pieces followed with two foliar applications . The modeling of potato seed use would be expected to be similar to that of an in - furrow application of a granular pesticide (no spray drift) so it is assumed that application efficiency is 100 percent and spray

drift loss is zero and the model setting to account for placement at a specified depth using PRZM chemical application method (CAM) is 8 . Depth of potato seed plant varie d in literature from about 2 inches to 4 inches (5 to 10 cm). For an incorporation depth of 3 - cm or more when PRZM CAM = 8 the

12 TXR No. 0052287 13 http://www.epa.gov/oppefed1/models/water/pca_adjustment_dwa.html

## 11

surface water EDWCs were 0. The fol i ar applications would assume standard assumptions (spray drift and incorporation depth) for ground or aerial spray applications. To evaluate the difference between application method, a single application of fenamidone assuming treated potato seed (CAM=8 and incorporation depth was 2 cm) was compared to a single foliar application (Table 7 ). It can be seen that the concentrations from the seed treatment application ( e.g. , 0.84 μg/L) are less than the foliarly applied applications ( e.g. , 11.78) (Table 7 ). Theref ore, qualitatively

it would be expected that a the yearly application of fenamidone to potatoes with one application as a seed treatment and two by aerial spray applications would result in lower EDWCs then with three aerial or ground applications. **T able**  **5 . Crop management PRZM/EXAMS inputs used in aquatic exposure modeling for**  **Fenamidone. PRZ** **M/EXAMS Input Parameter Input**  **Value and Unit** Labeled Crop Crop Scenarios Application Rate Yearly Rate (Num

ber of Applications ) Retreatment Time Interval Application Date (month - day) **Potato Foliar** FL Potato, ME Potato  Application Rate: 0.267 lb a.i./A (0.2 9 9 kg ai/ha  0.80 lb a.i./A per year (3 applications @ max rate)  5 days between applications  First Application Date (month - day) :  FL: 03 - 04 ME : 07 - 15 **Potato Seed Treatm ent**  **and Foliar Potato** FL Potato, ME Potato  Potato Seed: 0.245 lb ai./ac (0.274 kg ai/ha) a 

###  Foliar Application Rate: 0.267 lb a.i./A (0.2 9 9 kg ai/ha)  ( 1 seed treatment + 2 foliar applications per season)  0.80 lb a.i./A per year  5 days between applications  Planting Date:  1 st 

### Application and 2 nd 

### Application Date: FL: 01 - 01 FL: 0 3 - 0 4 FL: 01 - 01 FL: 03 - 09 FL: 01 - 01 FL: 03 - 14 ME: 07 - 15 ME : 07 - 20 **Potato Seed Treatm ent**  **vs Single**  **Foliar Application b**  

### FL Potato, ME Potato  Potato Seed: 0.2 67 lb ai./ac (0. 299 kg ai/ha) a 

###  Foliar Rate: 0.267 lb a.i./A (0.2 9 9 kg ai/ha)  ( 1 applications per season)  Planting Date:  1 st 

### Application Date: FL: 01 - 01 ME: 04 - 25 **Onions, Bulb Vegetables** GA Onion, CA Onion, WA Onion  Application Rate: 0.178 lb a.i./A (0.199 kg ai/ha)  0.71 lb a.i./A per year (4 applications @ max rate)  5 days between applications  First Application Date: GA: 04 - 15

## 12

**PRZ M/EXAMS Input Parameter**  **Input Value and Unit**  CA: 02 - 01 WA: 07 - 30 **Beans, Succulent** MI Bean, OR Snapbean  Application Rate: 0.267 lb a.i./A (0.2 9 9 kg ai/ha)  0.80 lb a.i./A per year (3 applications per season)  5 days between applications  First Application Dates: MI: 08 - 01 OR: 07 - 01 **Ginseng MN Sugarbeet**   Application Rate: 0.267 lb a.i./A (0.299 kg ai/ha)  0.80 lb a.i./A per year (3 applications @ max rate)  3 applications per season at maximum rate  14 days between applications  First Application Date: 08 - 15 **MI Asparagus**  Application Rate: 0.267 lb a.i./A ( 0.299 kg ai/ha)  0.80 lb a.i./A per year (3 applications @ max rate)  3 applications per season at maximum rate  14 days between applications  First Application Date: 08 - 15 Chemical Application Method (CAM) c 

### Aerial and Ground Applications CAM = 2, linear foliar based on crop canopy CAM = 8 d 

### for potato seed treatment ; Incorporation depth set as 2 cm Application Efficiency Aerial Applications = 0.95 Ground Applications = 0.99 Potato Seed Piece Treatment = 1.0 (same as granular) Spray Drift Fraction Aerial Applications = 0.16 Ground Applications = 0.064 Potato Seed Piece Treatment = 0.00 (same as granular) a Potato seed treatment rate (0.274 kg ai/ha) based upon estimate provide by Registrant (MRID 48977101, pages 6 and 7) EFED estimated a potato seed treatment rate of 0.266 kg ai/ha). b Single application potato seed treatment and aerial foliar application means to evaluate significance of spray drift. c CAM also required for PRZM - GW d Potatoe seed are planted at a depth of 5 to 10 cm, w hen CAM = 8 was used , any incorporation (planting depth) of > 3 cm, EDWCs were 0. 

## GROUNDWATER Total fenamidone residues were also estimated in groundwater. Tier I and II groundwater EDWCs for fenamidone residues use were derived with PRZM - GW (Pesticide Root Zone Model for Groundwater, version 1.0, August 31, 2012 ), using the GW - GUI(Graphical User Interface, version 1.0, August 31, 2012 ). Currently , the environmental fate input parameters are limited to aerobic soil metabolism halflife, hydrolysis, and sorption (Koc 

## ) in PRZM - GW (Table 4). Pestic ide usage information is limited to rate and number of applications, date of application, and chemical application method (CAM), foliar or soil applied applications. Spray drift and efficiency

are not considered. However, wash - off is considered for a foliar application in the same manner as surface water.

## 13

The six scenarios (Table 8), currently available with PRZM - GW, developed to represent conditions known to be vulnerable to groundwater contamination were also used in this assessment. Previously , c oncentration s of total residues in groundwater were estimated using the S creening C oncentration In Ground W ater model (SCI - GROW) (Version 2.3). For comparison purposes, EDWCs were also calculated using the Screening Concentration in Ground Water model (SCI GROW v2.3, compiled 08/08/03). Input parameters for SCI - GROW modeling are shown in Table 6. SCI - GROW does not differentiate between method of application, but only considers numbers and rate of application. **Table 6**  **. SCI -**  **GROW Input Parameters for Total Fenamidone** 

**Model Param eter**  **Value Reference**  Koc 

### (L/mg - OC) 26 MRID 45385824 Aerobic Soil Half

- life (days) 1000 days a 

### MRID 45385819 a Because the SCI - GROW model requires an input value, a half - life of 1000 days was used as a surrogate half - life for total fenamidone residues 

### . 

## Modeling Results The EDWCs for total fenamidone residues in surface water for the proposed new uses are predic ted to be no greater than 49.19 μg/L and 12.96 μg/L , the 1 - in - 10 year daily peak and annual mean concentration , respectivel y , or 8.21 μg/L the 30 - ye ar annual mean concentration s (Table 7 ). The total fenamidone concentrations vary depending upon the application dates and the method of application (e.g., seed treatment or aerial spray) and scenario . The 1 - in - 10 year peak EDWCs ranged from 6.85 to 49.19 μg/L , the 1 - in - 10 year average concentrations ranged from 2.71 to 12.96 μg/L, and the 30 year average concentration ranged from 1.80 to 8.21 μg/L . Representative model outputs are included in Appendix 3. **Table 7**  **. PRZ M/EXAMS**  **Surface Water E DW**  **Cs (** **with PCA**  **= 0.91 )**  **Modeled Use Scenario**  **#apps/rate (lb a.i./A** **) 1**  **- in**  **- 10 year**  **30 -** **year ave**  **rage P**  **eak 10 yr**  **average Comparison of**  **S eed**  **Potato T**  **reatment vs .**  **a S**  **ingle F**  **oliar A** **pplication** 

### [μg/L] Potato (seed treatment) a FL Potato 1 @ 0.267 0.76 0.11 0.03 Potato (foliar) b FL Potato 1 @ 0.267 10.72 1.63 0.86 Potato (seed treatment) a1 ME Potato 1 @ 0.267 0.56 0.15 0.05 Potato (seed treatment) a2 ME Potato 1 @ 0.267 9.92 2.68 1.26 Potato (foliar) b1 ME Potato 1 @ 0.267 10.53 2.90 1.48 Potato (foliar) b2 ME Potato 1 @ 0.267 9.92 2.68 1.26 **Proposed New Uses and Potato Seed Treatment** Potato (foliar) c FL Potato 3 @ 0.267 30.98 5.26 2.78 Potato (foliar) d FL Potato 3 @ 0.267 27.69 5.14 2.79

## 14 **Modeled Use Scenario**  **#apps/rate (lb a.i./A** **) 1**  **- in**  **- 10 year**  **30 -** **year ave**  **rage** Potato (foliar) e FL Potato 3 @ 0.267 36.31 5.36 2.72 Potato (foliar no drift) f FL Potato 3 @ 0.267 35.38 4.97 2.19 Potato ( foliar no drift) g ME Potato 3 @ 0.267 16.53 5.80 2.32 Potato (foliar) h ME Potato 3 @ 0.267 19.85 6.93 1.80 Potato (foliar) i FL Potato 3 @ 0.267 42.82 5.93 2.28 Potato (foliar no drift) j FL Potato 3 @ 0.267 44.10 6.27 2.80 Onions (Bulb Vegetables) CA Onion 4 @ 0.178 6.85 2.71 1.99

“ GA Onion 4 @ 0.178 26.20 4.08 1.98 “ WA Onion 4 @ 0.178 9.62 4.55 2.93 Beans (Succulent) MI Bean 3 @ 0.267 **49.19 12.96**  **8.21** “ OR Snap bean 3 @ 0.267 23.40 5.23 2.45 Ginseng MN Sugarbeet 3 @ 0.267 31.23 10.70 7.23 “ MI Asparagus 3 @ 0.267 9.80 4.94 3.48 a Treated potato seed applied via CAM = 8, 2 cm depth of incorporation ; no drift and application efficiency = 1.0. b Applied via CAM = 2; drift =0.16 and application efficiency = 0.95 a1 Application Date: 07 - 15; Treated potato seed applied via CAM = 8, 2 cm depth of incorporation; no drift and application efficiency = 1.0. a2 Application Date: 04 - 25; Treated potato seed applied via CAM = 8, 2 cm depth of incorporation; no drift and application efficiency = 1.0. b1 Application Date: 07 - 15; Treated potato s eed applied via CAM = 2, 2 cm depth of incorporation; drift=0.16 and application efficiency = 0.95. b2 Application Date: 04 - 25; Treated potato seed applied via CAM = 2, 2 cm depth of incorporation; drift=0.16 and application efficiency = 0.95. c A pplicatio n dates 01 - 01; 01 - 06; 01 - 11 ; CAM = 2; drift = 0.16 and application efficiency 0.95. d A pplication date s 01 - 01; 03 - 04; 03 - 09 ; CAM = 2; drift = 0.16 and application efficiency 0.95. e A pplication dates 01 - 01; 03 - 09; 03 - 14 ; CAM = 2; drift = 0.16 and application efficiency 0.95. f A pplication date s 01 - 01; 0 3 - 14; 0 3 - 19 ; CAM = 2; drift = 0.00 and application efficiency 1.00. g A pplication date s 0 7 - 15 ; 07 - 20 ; 07 - 25; CAM = 2; drift = 0. 00 and application efficiency 1.00 . h A pplication date s 0 7 - 15 ; 07 - 20 ; 0 7 - 25; CAM = 2; drift = 0. 16 and application efficiency 0.95 . i A pplication date s 0 3 - 04 ; 03 - 09 ; 03 - 14; CAM = 2; drift = 0.16 and application efficiency 0.95. j A pplication date s 0 3 - 04 ; 03 - 09 ; 03 - 14; CAM = 2; drift = 0.00 and application efficiency 1.00. 

## The highest daily total fenamidone residue concentration in shallow groundwater estimated b y PRZM - GW is 207 μg/L (Table 8 ). PRZM - GW estimates for peak concentration ranged from 41.5 to 207.0 μg/L . The post -breakthrough averages (after equilibrium is establ ished) ranged from 25.1 to 139 μg/L. Average time to breakthrough ranged from 430 days to 1415 days. Date of application had little influence on predicted groundwater EDWCs. **Table 8**  **. PRZ** **M -**  **GW Estimates of Groundwa ter EECs [μg/L**  **] Groundw**  **ater Scenario**  **Application Rate**

**#apps/rate Highest daily value**  **Post Breakthrough Average**  **Average Breakthrough Tim**  **e (days)**  Delmarva 3 @ 0.267 185 120 429 FL Central Ridge 3 @ 0.267 143 95.5 450 FL Potato 3 @ 0.267 111 71.5 792 GA Coastal Plain 3 @ 0.267 41.5 25.1 1415 NC Coastal Plain 3 @ 0.267 84.2 59.7 1263 WI Central Sands 3 @ 0.267 **207 139**  859

## 15

The estimated groundwater concentrations from SCI - GROW, which are being presented as a comparison to the PRZM - GW estimates during the first year of PRZM - GW implementation, are the same as the previous drinking water assessment , i.e., total residue concentration of 178 μg/L , as no additional environmental fate data are available and the ye arl y maximum applications rates have remained the same. The probable reason that the SCI - GROW estimate and the PRZM - GW results are similar is that PRZM - GW includes hydrolysis which is not considered in SCI - GROW. **Table 9**  **. SCI -**  **GROW Estimated Exposure Concentrations of Total Residues in D rinking Water Drawn from**  **Groundw ater**  **(previous DWA 1**  

### ) **and Current Assessment**

**Use Scenario Total Application Rate**  **(lbs ai/A) Total Residues Concentration**  **(μg/L)** Potato (3 foliar) 1 

### 0.80 1 

### 178 Potato ( 3 apps ) current assessment 0.80 178 1 USEPA, 2007; D332878, D316085, D316083, D339503

## 16

**Appendix 1. Metabolite Company Code (ID), Chemical Name**  **s ,**  **Degradation Process and Study where Degradate was observed and Structures.**  **Appendix 1 .**  **Table 1. Recommended**  **metabolites for inclusion in the DWA for proposed new uses .**  **Company Code**  **(ID) Che**  **mi cal Name**  **Degradation Process and Study where observed** RPA- 412636 (S

) - Methyl - 5 - phenylimidazolidine - 2,4 - dione CAS Reg. No. 27539 - 12 - 4 Cleavage of the -N -N - bond of fenamidone and elimination of the methylthio group Aerobic soil and aerobic water- sediment systems; Field RPA- 412 7 08 (5 S

) - 3,5 - dihydro - 5 - methyl - 2 - (methylthio) - 5 - phenyl - 4H

- imidazole - 4 - one CAS Reg. No. 332855 - 82 - 0 Cleavage of the -N -N - bond of fenamidone. This metabolite may be considered as the immediate precursor to RPA- 412636 Aerobic soil and aerobic water- sediment systems; Hydrolysis (pH 4; 9); Photolysis RPA- 411639 (5 S

) - 3,5 - 5 - methyl - 2 - (methylthio) - 3 - [(4 - nitrophenyl)amino] - 5 -phenyl - 4H - imidazole 4 - one Nitration of the -N - phenyl (anilo) group at the C - 4 position .Bridge - intact product Can form RPA - 412708 by cleavage of the

-N -N - bond Aerobic soil and aerobic water- sediment systems; RPA- 413255 (5 S

) - 3,5 - 5 - methyl - 2 - (methylthio) - 3 - [(2 - nitrophenyl)amino] - 5 -phenyl - 4H - imidazole 4 - one Nitration of the -N - phenyl (anilo) group at the C - 2 position . Bridge - intact product. Can form RPA- 412708 by cleavage of the -N -N - bond Aerobic soil and aerobic water- sediment systems; RPA- 409446 5 - Methyl - 3 - [(4 - nitrophenyl)amino - 5

— 2,4 - imidazolidinedione (The code for the S- enantiomer is RPA221607) Nitration of the -N - phenyl (anilo) group at C - 2 position Bridge intact product; Elimination of the methylthio group. Can form RPA- 412636 by cleavage of the

-N -N - bond Aerobic soil metabolism RP - 410995 5 - Methyl - 3 - [(2 - nitrophenyl)amino - 5

— 2,4 - imidazolidin edione (The code for the S- enantiomer is RPA221701) Nitration of the -N - phenyl (anilo) group at C - 2 position Bridge intact product; Elimination of the methylthio group. Can form RPA- 412636 by cleavage of the -N -N - bond Aerobic soil metabolism 

### Appendix 1. Table 2. **Chemical Structures** Name Structure

fenamidone; RPA 407213 (5 S ) - 3,5 - dihydro - 5 - methyl - 2 - (methylthio) - 5 -phenyl - 3 - (phenylamino) - 4H

- imidazol - 4 - one C H 3 N N O S C H 3 N H * 14 C -N - phenyl - fenamidone C H 3N N O S C H 3 N H *

1 4 C - C - phenyl - fenamidone N N CH 3 O S CH 3 N H

## 17

Name Structure 

### RPA 408056 (racemic mixture) RPA 412708 (S - enantiomer) {note some documents have ID this as RPA 412108} 5 - methyl - 2 - methylthio - 5 -phenyl - 3,5 - dihydroimidazol - 4 - one 

### RPA 405862 (racemic mixture) RPA 410193 (S enantiomer) 5 - methyl - 5 - phenyl - 3 - phenylamino - imidazolidin - 2,4 - dione



### RPA 717879 (racemic mixture) RPA 412636 (S - enantiomer) 5 - methyl - 5 - phenylimidazolidine - 2,4 - dione RPA 413255 (5 S ) - 5 - methyl - 2 - (methylthi o ) - 3 - [(2 - nitrophenyl)amino] - 5 - phenyl - 3,5 - dihydro - 4H

- imidazol - 4 - one RPA 410914 (racemic mixture) RPA 411639 (5 S ) - 5 - methyl - 2 - (methylthio) - 3 - [(4 - nitrophenyl)amino] - 5 - phenyl - 3 ,5 - dihydro - 4H

- imidazol - 4 - one RPA 406012 (racemic mixture) RPA 410995 (5 S ) - 5 - methyl - 3 - [(2 -nitrophenyl)amino] - 5 - phenylimidazolidine - 2,4 - dione RPA 409446 (5 S ) - 5 - methyl - 3 - [(4 -nitrophenyl)amino] - 5 - phenylimidazolidine - 2,4 - dione RPA 407213 - dimer (5 S,5' S ) - 3,3' - (1,2 - diphenylhydrazine - 1 ,2 - diyl)bis[5 - methyl - 2 - (methylthi o ) - 5 - phenyl - 3,5 - dihydro - 4Himidazol - 4 - one] N N C H 3 O S C H 3 H

N H N C H 3 O O N H

N

H N C H 3 O O H

## 18

Name Structure aniline

## 19

**Appendix 2. Modeling Assumptions and**  **Concentrations not adjusted by PCA.** PE5 does not easily

allow for mixed application methods (seed treatment with foliar applications) although PRZM does). To qualitatively evaluate the difference, one application of fenamidone as a potato seed (chemical a pplication method (CAM) = 8 , incorporation depth = 2 cm, drift = 0.0, efficiency = 100%) and one foliar application as an aerial spray (CAM = 2, drift = 0.16 an application efficiency = 95%) were run for each potato scenario ( Appendix 2 Table 1 ). CAM = 8 allows for the placement (incorporation) of the pesticide ( i.e. , seed potato) at a specified depth. When CAM =8, incorporation depths greater than 4 cm results in EDWCs of 0.0 concentration. As expected the concentrations from the seed treatments (0.84 and 0.77 μg/L) are less than the singular foliar application (11.78 and 11.57 μg/L). To considered the different application dates associated with the different methods of application (seed treatment vs foliar) combinations of different application dates were also considered (Appendix 2 Table 1). PRZM/EXAMs total fenamidone concentrations not adjusted by the PCA are given in Appendix 2 Table 1. **Appendix 2 Table**  **1 .**  **PRZ M/EXAMS Surface Water EECs [μg/L](without PCA)** 

**Crop Scenario**  **#apps/rate (lb a.i./A** **) 1**  **- in**  **- 10 year**  **Long -**  **term**

**Peak Average**  **30 -** **year Average**  Comparison of Potato Seed Treatment vs Single Foliar Application Potato (seed treatment) a FL Potato 1 @ 0.267 0.84 0.12 0.03 Potato (foliar) b FL Potato 1 @ 0.267 11.78 1.79 0.94 Potato (seed treatment) a1 ME Potato 1 @ 0.267 0.77 0.19 0.08 Potato (seed treatment) a2 ME Potato 1 @ 0.267 0.62 0.16 0.05 Potato (foliar) b 1 ME Potato 1 @ 0.267 11.57 3.19 1.63 Potato (foliar) b2 ME Potato 1 @ 0.267 10.90 2.95 1.38 Potato (foliar) c FL Potato 3 @ 0.267 34.04 5.78 3.06 Potato (foliar) d FL Potato 3 @ 0.267 30.43 5.65 3.07 Potato (foliar) e FL Potato 3 @ 0.267 39.90 5.89 2.99 Potato ( foliar no drift) f FL Potato 3 @ 0.267 38.88 5.46 2.41 Potato ( foliar no drift) g ME Potato 3 @ 0.267 18.16 6.37 2.55 Potato (foliar) h ME Potato 3 @ 0.267 21.81 7.62 1.98 Potato (foliar) i FL Potato 3 @ 0.267 47.06 6.52 2.51 Potato (foliar no drift) j FL Potato 3 @ 0.267 48.46 6.89 3.08

Three Aerial Foliar Applications Onions (Bulb Vegetables) CA Onion 4 @ 0.178 7.53 2.98 2.19

“ GA Onion 4 @ 0.178 28.79 4.48 2.18 “ WA Onion 4 @ 0.178 10.57 5.00 3.22 **Beans (Succulent) MI Bean**  **3 @ 0.267**  **54.05 14.24**  **9.02** “ OR Snap bean 3 @ 0.267 25.71 5.75 2.69 Ginseng MN Sugarbeet 3 @ 0.267 34.32 11.76 7.94 “ MI Asparagus 3 @ 0.267 10.77 5.43 3.82

## 20 a Treated potato seed applied via CAM = 8, 2 cm depth of incorporation ; no drift and application efficiency = 1.0. b Applied via CAM = 2; drift =0.16 and application efficiency = 0.95 a1 Application Date: 07 - 1 5 ; Treated potato seed applied via CAM = 8, 2 cm depth of incorporation; no drift and application efficiency = 1.0. a2 Application Date: 04 - 25; Treated potato seed applied via CAM = 8, 2 cm depth of incorporation; no drift and application efficiency = 1.0. b1 Application Date: 07 - 15; Treated potato seed applied via CAM = 2, 2 cm depth of incorporation; drift=0.16 and application efficiency = 0.95. b2 Application Date: 04 - 25; Treated potato seed applied via CAM = 2, 2 cm depth of incorporation; drift=0.16 and application efficiency = 0.95. c A pplication date s 01 - 01; 01 - 06; 01 - 11 ; CAM = 2; drift = 0.16 and application efficiency 0.95 . d A pplication date s 01 - 01; 03 - 04; 03 - 09 ; CAM = 2; drift = 0.16 and application efficiency 0.95 . e A pplication dates 01 - 01; 03 - 09; 03 - 14 ; CAM = 2; drift = 0.16 and application efficiency 0.95 . f A pplication date s 01 - 01; 0 3 - 14; 0 3 - 19 ; CAM = 2; drift = 0.0 0 and application efficiency 1.00 . g A pplication date s 0 7 - 15 ; 07 - 20 ; 07 - 25; CAM = 2; drift = 0. 00 and application efficiency 1.00 h A pplication date s 0 7 - 15 ; 0 7 - 20 ; 0 7 - 25 ; CAM = 2; drift = 0. 16 and application efficiency 0.95 . i A pplication date s 0 3 - 04 ; 03 - 09 ; 03 - 14; CAM = 2; drift = 0.16 and application efficiency 0.95 . j A pplication date s 0 3 - 04 ; 03 - 0 9 ; 03 - 14; CAM = 2; drift = 0.00 and application efficiency 1.00 .

## 21

**Appendix 3. Representative Model Outputs for PRZM/EXAMS (PE5), PRZM -**  **GW, and SCI**  **- GROW.** 

stored as MIbean.out Chemical: fenamidone PRZM environment: MIbeansSTD.txt modified Tueday, 29 May 2007 at 13:56:44 EXAMS environment: ir298.exv modified Tueday, 26 August 2008 at 06:14:08 Metfile: w14826.dvf modified Tueday, 26 August 2008 at 06:15:04 Water segment concentrations (ppb) Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 54.22 53.04 50.01 41.98 37.01 11.78 1962 16.68 16.43 15.42 13.41 12.11 6.878 1963 18.74 18.34 17.34 15.05 13.41 5.319 1964 14.26 13.97 13 11.67 10.66 5.283 1965 52.47 51.33 46.88 39.07 34.47 12.55 1966 15.19 14.96 14.05 12.22 11.01 8.032 1967 22.03 21.56 19.79 17.25 1 5.57 6.682 1968 134 131 120 99.04 87.18 29.88 1969 38.12 37.55 35.25 30.67 27.7 14.32 1970 30.33 29.66 27.31 23.98 21.51 8.795 1971 10.21 10.05 9.437 8.211 7.623 5.639 1972 17.98 17.59 16.15 13.79 12.27 5.358 1973 30.43 29.8 27.68 23.41 20.82 8.36 1974 12. 28 12.09 11.35 9.862 9.273 6.706 1975 101 98.76 91.66 76.89 67.83 22.59 1976 30.78 30.31 28.46 24.75 22.3 13.52 1977 11.39 11.17 10.34 8.799 8.476 5.319 1978 12.57 12.37 11.55 10.55 9.857 4.762 1979 10.5 10.27 9.388 8.108 7.376 3.942 1980 12.52 12.24 11.42 10.21 9.256 4.038 1981 16.48 16.16 15.02 13.05 11.74 5.243 1982 20.57 20.12 18.45 16.14 14.41 6.403 1983 16.11 15.74 14.49 13.36 12.25 6.084 1984 15.94 15.58 14.67 13.08 12.04 5.719 1985 47.53 46.5 43.44 36.54 32.31 11.79 1986 38.69 37.86 35.49 30.73 27.3 5 13.24 1987 21.76 21.28 20.16 17.44 15.69 9.06 1988 28.1 27.45 25.46 21.48 19.1 8.353 1989 20.4 19.96 19.1 16.59 14.92 7.405 1990 24.77 24.22 22.26 19.24 17.09 7.406 Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.032258064516129 134 131 120 99.04 87.18 29.88 0.0645161290322581 101 98.76 91.66 76.89 67.83 22.59 0.0967741935483871 54.22 53.04 50.01 41.98 37.01 14.32 0.129032258064516 52.47 51.33 46.88 39.07 34.47 13.52 0.161290322580645 47.53 46.5 43.44 36.54 32.31 13.24 0.193548387096774 3 8.69 37.86 35.49 30.73 27.7 12.55 0.225806451612903 38.12 37.55 35.25 30.67 27.35 11.79 0.258064516129032 30.78 30.31 28.46 24.75 22.3 11.78 0.290322580645161 30.43 29.8 27.68 23.98 21.51 9.06 0.32258064516129 30.33 29.66 27.31 23.41 20.82 8.795 0.35483870 9677419 28.1 27.45 25.46 21.48 19.1 8.36 0.387096774193548 24.77 24.22 22.26 19.24 17.09 8.353 0.419354838709677 22.03 21.56 20.16 17.44 15.69 8.032 0.451612903225806 21.76 21.28 19.79 17.25 15.57 7.406 0.483870967741936 20.57 20.12 19.1 16.59 14.92 7.405

## 22

0.516129032258065 20.4 19.96 18.45 16.14 14.41 6.878 0.548387096774194 18.74 18.34 17.34 15.05 13.41 6.706 0.580645161290323 17.98 17.59 16.15 13.79 12.27 6.682 0.612903225806452 16.68 16.43 15.42 13.41 12.25 6.403 0.645161290322581 16.48 16.16 15.02 13.36 12.11 6.084 0.67741935483871 16.11 15.74 14.67 13.08 12.04 5.719 0.709677419354839 15.94 15.58 14.49 13.05 11.74 5.639 0.741935483870968 15.19 14.96 14.05 12.22 11.01 5.358 0.774193548387097 14.26 13.97 13 11.67 10.66 5.319 0.806451612903226 12.57 12.37 11.55 10.55 9.857 5.319 0.838709677419355 12.52 12.24 11.42 10.21 9.273 5.283 0.870967741935484 12.28 12.09 11.35 9.862 9.256 5.243 0.903225806451613 11.39 11.17 10.34 8.799 8.476 4.762 0.935483870967742 10.5 10.27 9.437 8.211 7.623 4.038 0.967741935483871 10.21 10.05 9.388 8.108 7.376 3.942 0.1 54.045 52.869 49.697 41.689 36.756 14.24 Average of yearly averages: 9.0152 Inputs generated by pe5.pl - Novemeber 2006 Data used for this run: Output File: MIbean Metfile: w14826.dvf PRZM scenario: MIbeansS TD.txt EXAMS environment file: ir298.exv Chemical Name: fenamidone Description Variable Name Value Units Comments Molecular weight mwt 311.4 g/mol Henry's Law Const. henry 1.37e - 10 atm- m^3/mol Vapor Pressure vapr 2.6e - 9 torr Solubility sol 7.8 mg/L Kd Kd mg/L Koc Koc 26 mg/L Photolysis half

- life kdp 5.4 days Half - life Aerobic Aquatic Metabolism kbacw 137.78 days Halfife Anaerobic Aquatic Metabolism kbacs 1386.29 days Halfife Aerobic Soil Metabolism asm 0 days Halfife Hydrolysis: pH 7 407 days Half - life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.299 kg/ha Application Efficiency: AP PEFF 0.95 fraction Spray Drift DRFT 0.16 fraction of application rate applied to pond Application Date Date 1 - 8 dd/mm or dd/mmm or dd - mm or dd - mmm Interval 1 interval 5 days Set to 0 or delete line for single app. app. rate 1 apprate 0.299 kg/ha Interval 2 interval 5 days Set to 0 or delete line for single app. app. rate 2 apprate 0.299 kg/ha Record 17: FILTRA

IPSCND 1 UPTKF Record 18: PLVKRT PLDKRT FEXTRC 0.5 Flag for Index Res. Run IR Reservoir Flag for runoff calc. RUNOFF total none, monthly or total(average of entire run)

## 23

**SEED TREATMENT CAM = 8, depth placement 3 cm** stored as FLpotatoST3.out Chemical: fenamidone PRZM environment: FLpotatoNMC.txt modified Thuday, 14 June 2007 at 11:15:58 EXAMS environment: ir298.exv modified Tueday, 26 August 2008 at 06:14:08 Metfile: w13889.dvf modified Tueday, 26 August 2008 at 06:14:40 Water segment concentrations (ppb) Year Pe ak 96 hr 21 Day 60 Day 90 Day Yearly 1961 0 0 0 0 0 0 1962 0 0 0 0 0 0 1963 0 0 0 0 0 0 1964 0 0 0 0 0 0 1965 0 0 0 0 0 0 1966 0 0 0 0 0 0 1967 0 0 0 0 0 0 1968 0 0 0 0 0 0 1969 0 0 0 0 0 0 1970 0 0 0 0 0 0 1971 0 0 0 0 0 0 1972 0 0 0 0 0 0 1973 0 0 0 0 0 0 1974 0 0 0 0 0 0 1975 0 0 0 0 0 0 1976 0 0 0 0 0 0 1977 0 0 0 0 0 0 1978 0 0 0 0 0 0 1979 0 0 0 0 0 0 1980 0 0 0 0 0 0 1981 0 0 0 0 0 0 1982 0 0 0 0 0 0 1983 0 0 0 0 0 0 1984 0 0 0 0 0 0 1985 0 0 0 0 0 0 1986 0 0 0 0 0 0 1987 0 0 0 0 0 0 1988 0 0 0 0 0 0 1989 0 0 0 0 0 0 1990 0 0 0 0 0 0 Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.032258064516129 0 0 0 0 0 0 0.0645161290322581 0 0 0 0 0 0 0.0967741935483871 0 0 0 0 0 0 0.129032258064516 0 0 0 0 0 0 0.161290322580645 0 0 0 0 0 0 0.193548 387096774 0 0 0 0 0 0 0.225806451612903 0 0 0 0 0 0 0.258064516129032 0 0 0 0 0 0 0.290322580645161 0 0 0 0 0 0 0.32258064516129 0 0 0 0 0 0 0.354838709677419 0 0 0 0 0 0 0.387096774193548 0 0 0 0 0 0 0.419354838709677 0 0 0 0 0 0 0.451612903225806 0 0 0 0 0 0 0.483870967741936 0 0 0 0 0 0 0.516129032258065 0 0 0 0 0 0 0.548387096774194 0 0 0 0 0 0 0.580645161290323 0 0 0 0 0 0 0.612903225806452 0 0 0 0 0 0 0.645161290322581 0 0 0 0 0 0

## 24

0.67741935483871 0 0 0 0 0 0 0.709677419354839 0 0 0 0 0 0 0.741935483870968 0 0 0 0 0 0 0.774193548387097 0 0 0 0 0 0 0.806451612903226 0 0 0 0 0 0 0.838709677419355 0 0 0 0 0 0 0.870967741935484 0 0 0 0 0 0 0.903225806451613 0 0 0 0 0 0 0.935483870967742 0 0 0 0 0 0 0.967741935483871 0 0 0 0 0 0 0.1 0 0 0 0 0 0 Average of yearly averages: 0 Inputs generated by pe5.pl - Novemeber 2006 Data used for this run: Output File: FLpotatoST3 Metfile: w13889.dvf PRZM scenario: FLpotatoNMC.txt EXAMS environment file: ir298.exv Chemical Name: fenamidone Description Variable Name Value Units Comments Molecular weight mwt 311.4 g/mol Henry's Law Const. henry 1.37e - 10 atm- m^3/mol Vapor Pressure vapr 2.6e - 9 torr Solubility sol 7.8 mg/L Kd Kd mg/L Koc Koc 26 mg/L Photolysis half

- life kdp 5.4 days Half - life Aerobic Aquatic Metabolism kbacw 137.78 days Halfife Anaerobic Aquatic Metabolism kbacs 1386.29 days Halfife Aerobic Soil Metabolism asm 0 days Halfife Hydrolysis: pH 7 407 days Half - life Method: CAM 8 integer See PRZM manual Incorporation Depth: DEPI 3 cm Application Rat e: TAPP 0.299 kg/ha Application Efficiency: AP PEFF 1.0 fraction Spray Drift DRFT 0 fraction of application rate applied to pond Application Date Date 1 - 1 dd/mm or dd/mmm or dd - mm or dd - mmm Record 17: FILTRA

IPSCND 1 UPTKF Record 18: PLVKRT PLDKRT F EXTRC 0.5 Flag for Index Res. Run IR Reservoir Flag for runoff calc. RUNOFF total none, monthly or total(average of entire run)

## 25

**SEED TREATMENT, CAM = 8, Incorporation depth = 2 cm** stored as FLpotatoST.out Chemical: fenamidone PRZM environment: FLpotatoNMC.txt modified Thuday, 14 June 2007 at 11:15:58 EXAMS environment: ir298.exv modified Tueday, 26 August 2008 at 06:14:08 Metfile: w13889.dvf modified Tueday, 26 August 2008 at 06:14:40 Water segment concentrations (ppb) Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 0.0192 0.01858 0.01592 0.01141 0.00908 0.002663 1962 0.1225 0.1179 0.1047 0.07567 0.06046 0.01779 1963 0.253 0.2446 0.2094 0.1552 0.126 0.03748 1964 0.1479 0.1433 0.1238 0.08952 0.07167 0.02113 1965 0.0192 0.01847 0.016 22 0.0117 0.009315 0.00273 1966 0.003978 0.003871 0.003437 0.002708 0.002261 0.0006923 1967 0.1476 0.1434 0.1232 0.08876 0.07092 0.02084 1968 0.03033 0.0292 0.02496 0.01916 0.01574 0.004725 1969 0.1542 0.1484 0.1267 0.09189 0.07395 0.02191 1970 0.06951 0.0 6694 0.05741 0.04354 0.03516 0.01044 1971 0.2233 0.2153 0.1847 0.1329 0.1066 0.0316 1972 0.1867 0.1794 0.1567 0.1145 0.09169 0.02701 1973 0.1319 0.1269 0.1085 0.07828 0.06253 0.01851 1974 0.007785 0.007488 0.006387 0.004702 0.003836 0.001158 1975 0.04413 0.04243 0.03755 0.02717 0.02171 0.006398 1976 0.5496 0.5292 0.4535 0.3286 0.2624 0.07726 1977 0.3145 0.3031 0.2606 0.1893 0.1517 0.04495 1978 0.2102 0.2025 0.1845 0.1377 0.1109 0.03291 1979 1.021 0.9836 0.8691 0.6409 0.515 0.1527 1980 0.002787 0.002696 0.0 02483 0.001919 0.001631 0.0005435 1981 0.02415 0.02325 0.01992 0.01599 0.01331 0.004039 1982 0.1021 0.09822 0.08463 0.06093 0.05005 0.0151 1983 1.044 1.006 0.8832 0.6452 0.5181 0.1542 1984 0.008113 0.007853 0.006936 0.005131 0.004142 0.001315 1985 0.08296 0.07992 0.07129 0.05249 0.04194 0.01228 1986 0.1387 0.1343 0.1178 0.08517 0.06811 0.02011 1987 0.1826 0.1779 0.1529 0.1105 0.08855 0.02645 1988 0.8708 0.8402 0.7212 0.5219 0.418 0.1233 1989 0.02258 0.02172 0.01852 0.01544 0.01271 0.003869 1990 0.003979 0.0 03826 0.003259 0.002336 0.001862 0.0005491 Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.032258064516129 1.044 1.006 0.8832 0.6452 0.5181 0.1542 0.0645161290322581 1.021 0.9836 0.8691 0.6409 0.515 0.1527 0.0967741935483871 0.8708 0.8402 0. 7212 0.5219 0.418 0.1233 0.129032258064516 0.5496 0.5292 0.4535 0.3286 0.2624 0.07726 0.161290322580645 0.3145 0.3031 0.2606 0.1893 0.1517 0.04495 0.193548387096774 0.253 0.2446 0.2094 0.1552 0.126 0.03748 0.225806451612903 0.2233 0.2153 0.1847 0.1377 0.11 09 0.03291 0.258064516129032 0.2102 0.2025 0.1845 0.1329 0.1066 0.0316 0.290322580645161 0.1867 0.1794 0.1567 0.1145 0.09169 0.02701 0.32258064516129 0.1826 0.1779 0.1529 0.1105 0.08855 0.02645 0.354838709677419 0.1542 0.1484 0.1267 0.09189 0.07395 0.02191 0.387096774193548 0.1479 0.1434 0.1238 0.08952 0.07167 0.02113 0.419354838709677 0.1476 0.1433 0.1232 0.08876 0.07092 0.02084 0.451612903225806 0.1387 0.1343 0.1178 0.08517 0.06811 0.02011 0.483870967741936 0.1319 0.1269 0.1085 0.07828 0.06253 0.01851 0.5 16129032258065 0.1225 0.1179 0.1047 0.07567 0.06046 0.01779 0.548387096774194 0.1021 0.09822 0.08463 0.06093 0.05005 0.0151 0.580645161290323 0.08296 0.07992 0.07129 0.05249 0.04194 0.01228 0.612903225806452 0.06951 0.06694 0.05741 0.04354 0.03516 0.01044 0.645161290322581 0.04413 0.04243 0.03755 0.02717 0.02171 0.006398

## 26

0.67741935483871 0.03033 0.0292 0.02496 0.01916 0.01574 0.004725 0.709677419354839 0.02415 0.02325 0.01992 0.01599 0.01331 0.004039 0.741935483870968 0.02258 0.02172 0.01852 0.01544 0.01271 0.003869 0.774193548387097 0.0192 0.01858 0.01622 0.0117 0.009315 0.00273 0.806451612903226 0.0192 0.01847 0.01592 0.01141 0.00908 0.002663 0.838709677419355 0.008113 0.007853 0.006936 0.005131 0.004142 0.001315 0.870967741935484 0.007785 0.007488 0.00638 7 0.004702 0.003836 0.001158 0.903225806451613 0.003979 0.003871 0.003437 0.002708 0.002261 0.0006923 0.935483870967742 0.003978 0.003826 0.003259 0.002336 0.001862 0.0005491 0.967741935483871 0.002787 0.002696 0.002483 0.001919 0.001631 0.0005435 0.1 0.8 3868 0.8091 0.69443 0.50257 0.40244 0.118696 Average of yearly averages: 0.02982173 Inputs generated by pe5.pl - Novemeber 2006 Data used for this run: Output File: FLpotatoST Metfile: w13889.dvf PRZM scenario: FLpotatoNMC.txt EXAMS environment file: ir298.exv Chemical Name: fenamidone Description Variable Name Value Units Comments Molecular weight mwt 311.4 g/mol Henry's Law Const. henry 1.37e - 10 atm- m^3/mol Vapor Pressure vapr 2.6e - 9 torr Solubility sol 7.8 mg/L Kd Kd mg/L Koc Koc 26 mg/L Photolysis half

- life kdp 5.4 days Half - life Aerobic Aquatic Metabolism kbacw 137.78 days Halfife Anaerobic Aquatic Metabolism kbacs 1386.29 days Halfife Aerobic Soil Metabolism asm 0 days Halfife Hydrolysis: pH 7 407 days Half - life Method: CAM 8 integer See PRZM manual Incorporation Depth: DEPI 2 cm Application Rate: TAPP 0.299 kg/ha Application Efficiency: AP PEFF 1.0 fraction Spray Drift DRFT 0 fraction of application rate applied to pond Application Date Date 1 - 1 dd/mm or dd/mmm or dd - mm or dd - mmm Record 17: FILTRA

IPSCND 1 UPTKF Record 18: PLVKRT PLDKRT FEXTRC 0.5 Flag for Index Res. Run IR Reservoir Flag for runoff calc. RUNOFF total none, monthly or total(average of entire run)

## 27

**PRZM -**  **GW OUTPUT Wisconsin Central Sands** 

Fenamidone (Total Toxic Residues) **Outputs** Highest Dailey

Value (μg/L) = 207 Simulation Average (μg/L) = 125 Post - Breakthrough Average (μg/L) = 139 Average Breakthrough Time = 958.93 days Throughputs 12.76 **Inputs** Hydrolysis = 407 days Koc = 26 mL/goc Aerobic Soil M etabolism = 0 (stable) 3 applications @ 0.267 lb a.i./A (0.299 kg a.i./ha)

PRZM - GW INPUT 7/10/2013 12:16:57 PM; Enter chemical name or descriptive information.; Wisconsin Corn

- WI Central Sands User Interface Version: PRZM - GW (Version 1.01) ***Record 3 0.76 0.36 0 18 1 1 ***Record 6

0 ***Record 8

1 ***Record 9

1 0.25 90 100 1 10 10 10 0 100 ***Record 10 30 ***Record 11 010561 210761 201061 1 010562 210762 201062 1

## 28

010563 210763 201063 1 010564 210764 201064 1 010565 210765 201065 1 010566 210766 201066 1 010567 210767 201067 1 010568 210768 201068 1 010569 210769 201069 1 010570 210770 201070 1 010571 210771 201071 1 010572 210772 201072 1 010573 210773 201073 1 010574 210774 201074 1 010575 210775 201075 1 010576 210776 201076 1 010577 210777 201077 1 010578 210778 201078 1 010579 210779 201079 1 010580 210780 201080 1 010581 210781 201081 1 010582 210782 201082 1 010583 210783 201083 1 010584 210784 201084 1 010585 210785 201085 1 010586 210786 201086 1 010587 210787 201087 1 010588 210788 201088 1 010589 210789 201089 1 010590 210790 201090 1 ***Record 12 Place Holder ***Record 13 90 1 0 0 ***Record 15 Place Holder ***Record 16 1 561 0 1 4 0.299 1 0 31 561 0 2 4 0.299 1 0 5 661 0 2 4 0.299 1 0 1 562 0 1 4 0.299 1 0 31 562 0 2 4 0.299 1 0 5 662 0 2 4 0.299 1 0 1 563 0 1 4 0.299 1 0 31 563 0 2 4 0.299 1 0 5 663 0 2 4 0.299 1 0 1 564 0 1 4 0.299 1 0 31 564 0 2 4 0.299 1 0 5 664 0 2 4 0.299 1 0 1 565 0 1 4 0.299 1 0 31 565 0 2 4 0.299 1 0 5 665 0 2 4 0.299 1 0 1 566 0 1 4 0.299 1 0 31 566 0 2 4 0.299 1 0 5 666 0 2 4 0.299 1 0 1 567 0 1 4 0.299 1 0 31 567 0 2 4 0.299 1 0 5 667 0 2 4 0.299 1 0 1 568 0 1 4 0.299 1 0 31 568 0 2 4 0.299 1 0 5 668 0 2 4 0.299 1 0 1 569 0 1 4 0.299 1 0 31 569 0 2 4 0.299 1 0 5 669 0 2 4 0.299 1 0 1 570 0 1 4 0.2 99 1 0

## 29

31 570 0 2 4 0.299 1 0 5 670 0 2 4 0.299 1 0 1 571 0 1 4 0.299 1 0 31 571 0 2 4 0.299 1 0 5 671 0 2 4 0.299 1 0 1 572 0 1 4 0.299 1 0 31 572 0 2 4 0.299 1 0 5 672 0 2 4 0.299 1 0 1 573 0 1 4 0.299 1 0 31 573 0 2 4 0.299 1 0 5 673 0 2 4 0.299 1 0 1 574 0 1 4 0.299 1 0 31 574 0 2 4 0.299 1 0 5 674 0 2 4 0.299 1 0 1 575 0 1 4 0.299 1 0 31 575 0 2 4 0.299 1 0 5 675 0 2 4 0.299 1 0 1 576 0 1 4 0.299 1 0 31 576 0 2 4 0.299 1 0 5 676 0 2 4 0.299 1 0 1 577 0 1 4 0.299 1 0 31 577 0 2 4 0.299 1 0 5 677 0 2 4 0.299 1 0 1 578 0 1 4 0.299 1 0 31 578 0 2 4 0.299 1 0 5 678 0 2 4 0.299 1 0 1 579 0 1 4 0.299 1 0 31 579 0 2 4 0.299 1 0 5 679 0 2 4 0.2 99 1 0 1 580 0 1 4 0.299 1 0 31 580 0 2 4 0.299 1 0 5 680 0 2 4 0.299 1 0 1 581 0 1 4 0.299 1 0 31 581 0 2 4 0.299 1 0 5 681 0 2 4 0.299 1 0 1 582 0 1 4 0.299 1 0 31 582 0 2 4 0.299 1 0 5 682 0 2 4 0.299 1 0 1 583 0 1 4 0.299 1 0 31 583 0 2 4 0.299 1 0 5 683 0 2 4 0.299 1 0 1 584 0 1 4 0.299 1 0 31 584 0 2 4 0.299 1 0 5 684 0 2 4 0.299 1 0 1 585 0 1 4 0.299 1 0 31 585 0 2 4 0.299 1 0 5 685 0 2 4 0.299 1 0 1 586 0 1 4 0.299 1 0 31 586 0 2 4 0.299 1 0 5 686 0 2 4 0.299 1 0 1 587 0 1 4 0.299 1 0 31 587 0 2 4 0.299 1 0 5 687 0 2 4 0.299 1 0 1 588 0 1 4 0.299 1 0 31 588 0 2 4 0.299 1 0 5 688 0 2 4 0.299 1 0 1 589 0 1 4 0.299 1 0 31 589 0 2 4 0.2 99 1 0 5 689 0 2 4 0.299 1 0 1 590 0 1 4 0.299 1 0 31 590 0 2 4 0.299 1 0 5 690 0 2 4 0.299 1 0 ***Record 17

## 30 0 1 0 ***Record 18

0 0 0.5 ***Record 19 Place Holder * **Record 20 1000 0 0 0 0 0 2 1 1 0 ***Record 26

0 0 0 ***Record 27

3 0.1 0.7 4.0 ***Record 31 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.97 10.0 ***Record 32 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 5.6 ***Record 32A 2.00 25.0 ***Record 33

8 *** Record 34,36,37 Horizon 1

1 10 1.63 0.088 0 0 0 0.0017 0 0 1 0.0 88 0.034 0.46 0.1196 5.6 95 2.3 0 0 *** Record 34,36,37 Horizon 2

2 10 1.63 0.088 0 0 0 0.0017 0 0 5 0.088 0.034 0.46 0.1196 5.6 95 2.3 0 0 *** Record 34,36,37 Horizon 3

3 20 1.68 0.079 0 0 0 0.0017 0 0 20 0.079 0.025 0.14 0.0364 5.6 96 2.5 0 0 *** Record 34,36,37 Horizon 4

4 20 1.68 0.079 0 0 0 0.0017 0 0 20 0.079 0.025 0.09 0.0234 5.6 96 2.5 0 0 *** Record 34,36,37 Horizon 5

5 20 1.59 0.068 0 0 0 0.0017 0 0 20 0.068 0.016 0.09 0.0234 5.6 97 1.7 0 0 *** Record 34,36,37 Horizon 6

6 20 1.59 0.068 0 0 0 0.0017 0 0 20 0.068 0.016 0.08 0.0208 5.6 97 1.7 0 0 *** Record 34,36,37 Horizon 7

7 800 1.59 0.068 0 0 0 0.0017 0 0 50 0.068 0.016 0.07 0.0182 5.6 97 1.7 0 0 *** Record 34,36,37 Horizon 8

8 100 1.59 0.396 0 0 0 0.0017 0 0 50 0.396 0.001 0.07 0.0182 5.6 97 1.7 0 0 *** Record 40

0 *** Record 42

YEAR 10 YEAR 10 YEAR 10 0

## 31

*** Record 45

3 YEAR *** Record 46 DCON1 TAVE 33 34 1.0E3 INFL TCUM 33 33 0.0109 IRRG TSER

SCIGROW VERSION 2.3 ENVIRONMENTAL FATE AND EFFECTS DIVISION OFFICE OF PESTICIDE PROGRAMS U.S. ENVIRONMENTAL PROTECTION AGENCY

SCREENING MODEL FOR AQUATIC PESTICIDE EXPOSURE SciGrow version 2.3 chemical:fenamidone time is 4/ 2/2013 15:13:37

------------------------------------------------------------- ----------- Application Number of Total Use Koc Soil Aerobic rate (lb/acre) applications (lb/acre/yr) (ml/g) metabolism (days)

------------------------------------------------------------------------ 0.801 1.0 0.801 2.60E+01 1000.0

------------------------------------------------------------------------ groundwater screening cond (ppb) = 1.78E+02 ************************************************************************