STATE OF CALIFORNIA

ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENT

SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986

CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITY

FEBRUARY 8, 2013

The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and 

republish at least once per year the list of chemicals known to the State to cause cancer or 

reproductive toxicity. The identification number indicated in the following list is the Chemical 

Abstracts Service (CAS) Registry Number. No CAS number is given when several substances are 

presented as a single listing. The date refers to the initial appearance of the chemical on the list. For 

easy reference, chemicals which are shown underlined are newly added. Chemicals or endpoints 

shown in strikeout were placed on the Proposition 65 list on the date noted, and have subsequently 

been removed. 

Chemical Type of Toxicity CAS No. Date Listed

A-alpha-C (2-Amino-9H-pyrido cancer 26148-68-5 January 1, 1990 [2,3-b]indole)

Acetaldehyde cancer 75-07-0 April 1, 1988

Acetamide cancer 60-35-5 January 1, 1990

Acetazolamide developmental 59-66-5 August 20, 1999

Acetochlor cancer 34256-82-1 January 1, 1989

Acetohydroxamic acid developmental 546-88-3 April 1, 1990

2-Acetylaminofluorene cancer 53-96-3 July 1, 1987

Acifluorfen sodium cancer 62476-59-9 January 1, 1990

Acrylamide cancer 79-06-1 January 1, 1990

Acrylamide developmental, male 79-06-1 February 25, 2011

Acrylonitrile cancer 107-13-1 July 1, 1987

Actinomycin D cancer 50-76-0 October 1, 1989

developmental October 1, 1992

AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)] cancer 3688-53-7 July 1, 1987 acrylamide

Aflatoxins cancer --- January 1, 1988

Alachlor cancer 15972-60-8 January 1, 1989

Alcoholic beverages, when cancer --- July 1, 1988 associated with alcohol abuse

Aldrin cancer 309-00-2 July 1, 1988

All-trans retinoic acid developmental 302-79-4 January 1, 1989

Allyl chloride cancer 107-05-1 January 1, 1990 Delisted October 29, 1999

Alprazolam developmental 28981-97-7 July 1, 1990

Altretamine developmental, male 645-05-6 August 20, 1999

Amantadine hydrochloride developmental 665-66-7 February 27, 2001

Amikacin sulfate developmental 39831-55-5 July 1, 1990

2-Aminoanthraquinone cancer 117-79-3 October 1, 1989

p-Aminoazobenzene cancer 60-09-3 January 1, 1990

o-Aminoazotoluene cancer 97-56-3 July 1, 1987
4-Aminobiphenyl (4-amino- cancer 92-67-1 February 27, 1987

 diphenyl)

1-Amino-2,4-dibromo- cancer 81-49-2 August 26, 1997

 anthraquinone

3-Amino-9-ethylcarbazole cancer 6109-97-3 July 1, 1989

 hydrochloride

2-Aminofluorene cancer 153-78-6 January 29, 1999

Aminoglutethimide developmental 125-84-8 July 1, 1990

Aminoglycosides developmental --- October 1, 1992

1-Amino-2-methylanthraquinone cancer 82-28-0 October 1, 1989

2-Amino-5-(5-nitro-2-furyl)-1,3,4- cancer 712-68-5 July 1, 1987

 thiadiazole

4-Amino-2-nitrophenol cancer 119-34-6 January 29, 1999

Aminopterin developmental, female 54-62-6 July 1, 1987

Amiodarone hydrochloride developmental, female, 19774-82-4 August 26, 1997

male

Amitraz developmental 33089-61-1 March 30, 1999

Amitrole cancer 61-82-5 July 1, 1987

Amoxapine developmental 14028-44-5 May 15, 1998

Amsacrine cancer 51264-14-3 August 7, 2009

tert-Amyl methyl ether developmental 994-05-8 December 18, 2009

Anabolic steroids female, male --- April 1, 1990

Analgesic mixtures containing cancer --- February 27, 1987

 phenacetin

Androstenedione cancer 27208-37-3 May 3, 2011

Angiotensin converting enzyme developmental --- October 1, 1992

 (ACE) inhibitors

Aniline cancer 62-53-3 January 1, 1990

Aniline hydrochloride cancer 142-04-1 May 15, 1998

o-Anisidine cancer 90-04-0 July 1, 1987

o-Anisidine hydrochloride cancer 134-29-2 July 1, 1987

Anisindione developmental 117-37-3 October 1, 1992

Anthraquinone cancer 84-65-1 September 28, 2007

Antimony oxide (Antimony trioxide) cancer 1309-64-4 October 1, 1990

Aramite cancer 140-57-8 July 1, 1987

Areca nut cancer --- February 3, 2006

Aristolochic acids cancer --- July 9, 2004

Arsenic (inorganic arsenic cancer -- February 27, 1987 compounds)

Arsenic (inorganic oxides) developmental --- May 1, 1997

Asbestos cancer 1332-21-4 February 27, 1987

Aspirin (NOTE: It is especially developmental, female 50-78-2 July 1, 1990 important not to use aspirin

 during the last three months of pregnancy, unless specifically directed to do so by a physician because it may cause problems in the unborn child or

 complications during delivery.)

Atenolol developmental 29122-68-7 August 26, 1997

Auramine cancer 492-80-8 July 1, 1987

Auranofin developmental 34031-32-8 January 29, 1999

-2- Proposition 65 List of Chemicals
Avermectin B1 (Abamectin) developmental 71751-41-2 December 3, 2010

Azacitidine cancer 320-67-2 January 1, 1992

Azaserine cancer 115-02-6 July 1, 1987

Azathioprine cancer 446-86-6 February 27, 1987

Azathioprine developmental 446-86-6 September 1, 1996

Azobenzene cancer 103-33-3 January 1, 1990

Barbiturates developmental --- October 1, 1992

Beclomethasone dipropionate developmental 5534-09-8 May 15, 1998

Benomyl developmental, male 17804-35-2 July 1, 1991

Benthiavalicarb-isopropyl cancer 177406-68-7 July 1, 2008

Benz[a]anthracene cancer 56-55-3 July 1, 1987

Benzene cancer 71-43-2 February 27, 1987

Benzene developmental, male 71-43-2 December 26, 1997

Benzidine [and its salts] cancer 92-87-5 February 27, 1987

Benzidine-based dyes cancer --- October 1, 1992

Benzodiazepines developmental --- October 1, 1992

Benzo[b]fluoranthene cancer 205-99-2 July 1, 1987

Benzo[j]fluoranthene cancer 205-82-3 July 1, 1987

Benzo[k]fluoranthene cancer 207-08-9 July 1, 1987

Benzofuran cancer 271-89-6 October 1, 1990

Benzophenone cancer 119-61-9 June 22, 2012

Benzo[a]pyrene cancer 50-32-8 July 1, 1987

Benzotrichloride cancer 98-07-7 July 1, 1987

Benzphetamine hydrochloride developmental 5411-22-3 April 1, 1990

Benzyl chloride cancer 100-44-7 January 1, 1990

Benzyl violet 4B cancer 1694-09-3 July 1, 1987

Beryllium and beryllium compounds cancer --- October 1, 1987

Betel quid with tobacco cancer --- January 1, 1990

Betel quid without tobacco cancer --- February 3, 2006

2,2-Bis(bromomethyl)-1,3- cancer 3296-90-0 May 1, 1996 propanediol

Bis(2-chloroethyl)ether cancer 111-44-4 April 1, 1988

N,N-Bis(2-chloroethyl)-2- cancer 494-03-1 February 27, 1987 naphthylamine (Chlornapazine)

Bischloroethyl nitrosourea (BCNU) cancer 154-93-8 July 1, 1987 (Carmustine)

Bischloroethyl nitrosourea (BCNU) developmental 154-93-8 July 1, 1990 (Carmustine)

Bis(chloromethyl)ether cancer 542-88-1 February 27, 1987

Bis(2-chloro-1-methylethyl)ether, cancer --- October 29, 1999

 technical grade

Bitumens, extracts of steam-refined cancer --- January 1, 1990

 and air refined

Bracken fern cancer --- January 1, 1990

Bromacil lithium salt developmental 53404-19-6 May 18, 1999

Bromacil lithium salt male 53404-19-6 January 17, 2003

Bromate cancer 15541-45-4 May 31, 2002

Bromochloroacetic acid cancer 5589-96-8 April 6, 2010

Bromodichloromethane cancer 75-27-4 January 1, 1990

Bromoethane cancer 74-96-4 December 22, 2000

Bromoform cancer 75-25-2 April 1, 1991

-3- Proposition 65 List of Chemicals
1-Bromopropane (1-BP) developmental, female, 106-94-5 December 7, 2004

male

2-Bromopropane (2-BP) female, male 75-26-3 May 31, 2005

Bromoxynil developmental 1689-84-5 October 1, 1990

Bromoxynil octanoate developmental 1689-99-2 May 18, 1999

Butabarbital sodium developmental 143-81-7 October 1, 1992

1,3-Butadiene cancer 106-99-0 April 1, 1988

1,3-Butadiene developmental, female, 106-99-0 April 16, 2004

male

1,4-Butanediol dimethanesulfonate cancer 55-98-1 February 27, 1987

 (Busulfan)

1,4-Butanediol dimethanesulfonate developmental 55-98-1 January 1, 1989

 (Busulfan)

Butylated hydroxyanisole cancer 25013-16-5 January 1, 1990

Butyl benzyl phthalate (BBP) developmental 85-68-7 December 2, 2005

n-Butyl glycidyl ether male 2426-08-6 August 7, 2009

beta-Butyrolactone cancer 3068-88-0 July 1, 1987

Cacodylic acid cancer 75-60-5 May 1, 1996

Cadmium developmental, male --- May 1, 1997

Cadmium and cadmium cancer --- October 1, 1987

 compounds

Caffeic acid cancer 331-39-5 October 1, 1994

Captafol cancer 2425-06-1 October 1, 1988

Captan cancer 133-06-2 January 1, 1990

Carbamazepine developmental 298-46-4 January 29, 1999

Carbaryl cancer 63-25-2 February 5, 2010

Carbaryl developmental, male 63-25-2 August 7, 2009

Carbazole cancer 86-74-8 May 1, 1996

Carbon black (airborne, unbound cancer 1333-86-4 February 21, 2003 particles of respirable size)

Carbon disulfide developmental, female, 75-15-0 July 1, 1989

male

Carbon monoxide developmental 630-08-0 July 1, 1989

Carbon tetrachloride cancer 56-23-5 October 1, 1987

Carbon-black extracts cancer --- January 1, 1990

Carboplatin developmental 41575-94-4 July 1, 1990

N-Carboxymethyl-N-nitrosourea cancer 60391-92-6 January 25, 2002

Catechol cancer 120-80-9 July 15, 2003

Ceramic fibers (airborne particles cancer --- July 1, 1990 of respirable size)

Certain combined chemotherapy cancer --- February 27, 1987 for lymphomas

Chenodiol developmental 474-25-9 April 1, 1990

Chlorambucil cancer 305-03-3 February 27, 1987

Chlorambucil developmental 305-03-3 January 1, 1989

Chloramphenicol

 Delisted January 4, 2013

cancer 56-75-7 October 1, 1989

Chlorcyclizine hydrochloride developmental 1620-21-9 July 1, 1987

Chlordane cancer 57-74-9 July 1, 1988

-4- Proposition 65 List of Chemicals
Chlordecone (Kepone) cancer 143-50-0 January 1, 1988

Chlordecone (Kepone) developmental 143-50-0 January 1, 1989

Chlordiazepoxide developmental 58-25-3 January 1, 1992

Chlordiazepoxide hydrochloride developmental 438-41-5 January 1, 1992

Chlordimeform cancer 6164-98-3 January 1, 1989

Chlorendic acid cancer 115-28-6 July 1, 1989

Chlorinated paraffins (Average cancer 108171-26-2 July 1, 1989 chain length, C12; approximately 60 percent chlorine by weight)

p-Chloroaniline cancer 106-47-8 October 1, 1994

p-Chloroaniline hydrochloride cancer 20265-96-7 May 15, 1998

Chlorodibromomethane cancer 124-48-1 January 1, 1990 Delisted October 29, 1999

Chloroethane (Ethyl chloride) cancer 75-00-3 July 1, 1990

1-(2-Chloroethyl)-3-cyclohexyl- cancer 13010-47-4 January 1, 1988 1-nitrosourea (CCNU) (Lomustine)

1-(2-Chloroethyl)-3-cyclohexyl- developmental 13010-47-4 July 1, 1990

 1-nitrosourea (CCNU) Lomustine)

1-(2-Chloroethyl)-3-(4-methyl- cancer 13909-09-6 October 1, 1988 cyclohexyl) -1-nitrosourea (Methyl-CCNU)

Chloroform cancer 67-66-3 October 1, 1987

Chloroform developmental 67-66-3 August 7, 2009

Chloromethyl methyl ether cancer 107-30-2 February 27, 1987 (technical grade)

3-Chloro-2-methylpropene cancer 563-47-3 July 1, 1989

1-Chloro-4-nitrobenzene cancer 100-00-5 October 29, 1999

4-Chloro-o-phenylenediamine cancer 95-83-0 January 1, 1988

Chloroprene cancer 126-99-8 June 2, 2000

2-Chloropropionic acid male 598-78-7 August 7, 2009

Chlorothalonil cancer 1897-45-6 January 1, 1989

p-Chloro-o-toluidine cancer 95-69-2 January 1, 1990

p-Chloro-o-toluidine, strong acid cancer --- May 15, 1998 salts of

5-Chloro-o-toluidine and cancer --- October 24, 1997 its strong acid salts

Chlorotrianisene cancer 569-57-3 September 1, 1996

Chlorozotocin cancer 54749-90-5 January 1, 1992

Chlorsulfuron developmental, female, 64902-72-3 May 14, 1999

male

Chromium (hexavalent compounds) cancer --- February 27, 1987

Chromium (hexavalent compounds) developmental, female, 

male

--- December 19, 2008

Chrysene cancer 218-01-9 January 1, 1990

C.I. Acid Red 114 cancer 6459-94-5 July 1, 1992

C.I. Basic Red 9 cancer 569-61-9 July 1, 1989

 monohydrochloride

C.I. Direct Blue 15 cancer 2429-74-5 August 26, 1997

C.I. Direct Blue 218 cancer 28407-37-6 August 26, 1997

C.I. Disperse Yellow 3 cancer 2832-40-8 February 8, 2013

C.I. Solvent Yellow 14 cancer 842-07-9 May 15, 1998

Ciclosporin (Cyclosporin A; cancer 59865-13-3 January 1, 1992

 Cyclosporine) 79217-60-0

-5- Proposition 65 List of Chemicals
Cidofovir cancer, developmental, 113852-37-2 January 29, 1999

female, male

Cinnamyl anthranilate cancer 87-29-6 July 1, 1989

Cisplatin cancer 15663-27-1 October 1, 1988

Citrus Red No. 2 cancer 6358-53-8 October 1, 1989

Cladribine developmental 4291-63-8 September 1, 1996

Clarithromycin developmental 81103-11-9 May 1, 1997

Clobetasol propionate developmental, female 25122-46-7 May 15, 1998

Clofibrate cancer 637-07-0 September 1, 1996

Clomiphene citrate developmental 50-41-9 April 1, 1990

Clorazepate dipotassium developmental 57109-90-7 October 1, 1992

Cobalt metal powder cancer 7440-48-4 July 1, 1992

Cobalt [II] oxide cancer 1307-96-6 July 1, 1992

Cobalt sulfate cancer 10124-43-3 May 20, 2005

Cobalt sulfate heptahydrate cancer 10026-24-1 June 2, 2000

Cocaine developmental, female 50-36-2 July 1, 1989

Coconut oil diethanolamine cancer --- June 22, 2012

 condensate (cocamide

 diethanolamine)

Codeine phosphate developmental 52-28-8 May 15, 1998

Coke oven emissions cancer --- February 27, 1987

Colchicine developmental, male 64-86-8 October 1, 1992

Conjugated estrogens cancer --- February 27, 1987

Conjugated estrogens developmental --- April 1, 1990

Creosotes cancer --- October 1, 1988

p-Cresidine cancer 120-71-8 January 1, 1988

Cumene cancer 98-82-8 April 6, 2010

Cupferron cancer 135-20-6 January 1, 1988

Cyanazine developmental 21725-46-2 April 1, 1990

Cycasin cancer 14901-08-7 January 1, 1988

Cycloate developmental 1134-23-2 March 19, 1999

Cyclohexanol Delisted male 108-93-0 November 6, 1998 January 25, 2002

Cycloheximide developmental 66-81-9 January 1, 1989

Cyclopenta[cd]pyrene cancer 27208-37-3 April 29, 2011

Cyclophosphamide (anhydrous) cancer 50-18-0 February 27, 1987

Cyclophosphamide (anhydrous) developmental, female, 50-18-0 January 1, 1989

male

Cyclophosphamide (hydrated) cancer 6055-19-2 February 27, 1987

Cyclophosphamide (hydrated) developmental, female, 6055-19-2 January 1, 1989

male

Cyhexatin developmental 13121-70-5 January 1, 1989

Cytarabine developmental 147-94-4 January 1, 1989

Cytembena cancer 21739-91-3 May 15, 1998

D&C Orange No. 17 cancer 3468-63-1 July 1, 1990

D&C Red No. 8 cancer 2092-56-0 October 1, 1990

D&C Red No. 9 cancer 5160-02-1 July 1, 1990

D&C Red No. 19 cancer 81-88-9 July 1, 1990

Dacarbazine cancer 4342-03-4 January 1, 1988

Dacarbazine developmental 4342-03-4 January 29, 1999

Daminozide cancer 1596-84-5 January 1, 1990

-6- Proposition 65 List of Chemicals
Danazol developmental 17230-88-5 April 1, 1990

Dantron (Chrysazin; 1,8- cancer 117-10-2 January 1, 1992

 Dihydroxyanthraquinone)

Daunomycin cancer 20830-81-3 January 1, 1988

Daunorubicin hydrochloride developmental 23541-50-6 July 1, 1990

2,4-D butyric acid developmental, male 94-82-6 June 18, 1999

DDD (Dichlorodiphenyl- cancer 72-54-8 January 1, 1989 dichloroethane)

DDE (Dichlorodi- cancer 72-55-9 January 1, 1989 phenyldichloroethylene)

DDT (Dichlorodi- cancer 50-29-3 October 1 , 1987 phenyltrichloroethane)

o,p’-DDT developmental, female, 789-02-6 May 15, 1998

male

p,p’-DDT developmental, female, 50-29-3 May 15, 1998

male

DDVP (Dichlorvos) cancer 62-73-7 January 1, 1989

Demeclocycline hydrochloride developmental 64-73-3 January 1, 1992 (internal use)

2,4-DP (dichloroprop) developmental 120-36-5 April 27, 1999 Delisted January 25, 2002

N,N’-Diacetylbenzidine cancer 613-35-4 October 1, 1989

2,4-Diaminoanisole cancer 615-05-4 October 1, 1990

2,4-Diaminoanisole sulfate cancer 39156-41-7 January 1, 1988

4,4’-Diaminodiphenyl ether cancer 101-80-4 January 1, 1988 (4,4’-Oxydianiline)

2,4-Diaminotoluene cancer 95-80-7 January 1, 1988

Diaminotoluene (mixed) cancer --- January 1, 1990

Diazepam developmental 439-14-5 January 1, 1992

Diazoaminobenzene cancer 136-35-6 May 20, 2005

Diazoxide developmental 364-98-7 February 27, 2001

Dibenz[a,h]acridine cancer 226-36-8 January 1, 1988

Dibenz[a,j]acridine cancer 224-42-0 January 1, 1988

Dibenz[a,h]anthracene cancer 53-70-3 January 1, 1988

7H-Dibenzo[c,g]carbazole cancer 194-59-2 January 1, 1988

Dibenzo[a,e]pyrene cancer 192-65-4 January 1, 1988

Dibenzo[a,h]pyrene cancer 189-64-0 January 1, 1988

Dibenzo[a,i]pyrene cancer 189-55-9 January 1, 1988

Dibenzo[a,l]pyrene cancer 191-30-0 January 1, 1988

Dibromoacetic acid cancer 631-64-1 June 17, 2008

Dibromoacetonitrile cancer 3252-43-5 May 3, 2011

1,2-Dibromo-3-chloropropane cancer 96-12-8 July 1, 1987 (DBCP)

1,2-Dibromo-3-chloropropane male 96-12-8 February 27, 1987 (DBCP)

2,3-Dibromo-1-propanol cancer 96-13-9 October 1, 1994

Dichloroacetic acid cancer 79-43-6 May 1, 1996

Dichloroacetic acid male 79-43-6 August 7, 2009

p-Dichlorobenzene cancer 106-46-7 January 1, 1989

3,3’-Dichlorobenzidine cancer 91-94-1 October 1, 1987

3,3’-Dichlorobenzidine cancer 612-83-9 May 15, 1998

dihydrochloride

-7- Proposition 65 List of Chemicals
1,1-Dichloro-2,2-bis(p- developmental, male 72-55-9 March 30, 2010

 chlorophenyl)ethylene (DDE)

1,4-Dichloro-2-butene cancer 764-41-0 January 1, 1990

3,3’-Dichloro-4,4’-diaminodiphenyl cancer 28434-86-8 January 1, 1988

 ether

1,1-Dichloroethane cancer 75-34-3 January 1, 1990

Dichloromethane (Methylene cancer 75-09-2 April 1, 1988

 chloride)

Dichlorophene developmental 97-23-4 April 27, 1999

1,2-Dichloropropane cancer 78-87-5 January 1, 1990

1,3-Dichloro-2-propanol (1,3-DCP) cancer 96-23-1 October 8, 2010

1,3-Dichloropropene cancer 542-75-6 January 1, 1989

Dichlorphenamide developmental 120-97-8 February 27, 2001

Diclofop-methyl cancer 51338-27-3 April 6, 2010

Diclofop methyl developmental 51338-27-3 March 5, 1999

Dicumarol developmental 66-76-2 October 1, 1992

Dieldrin cancer 60-57-1 July 1, 1988

Dienestrol Delisted January 4, 2013 cancer 84-17-3 January 1, 1990

Diepoxybutane cancer 1464-53-5 January 1, 1988

Diesel engine exhaust cancer --- October 1, 1990

Diethanolamine cancer 111-42-2 June 22, 2012

Di(2-ethylhexyl)phthalate (DEHP) cancer 117-81-7 January 1, 1988

Di(2-ethylhexyl)phthalate (DEHP) developmental, male 117-81-7 October 24, 2003

1,2-Diethylhydrazine cancer 1615-80-1 January 1, 1988

Diethylstilbestrol (DES) cancer 56-53-1 February 27, 1987

Diethylstilbestrol (DES) developmental 56-53-1 July 1, 1987

Diethyl sulfate cancer 64-67-5 January 1, 1988

Diflunisal developmental, female 22494-42-4 January 29, 1999

Diglycidyl ether male 2238-07-5 August 7, 2009

Diglycidyl resorcinol ether (DGRE) cancer 101-90-6 July 1, 1989

Dihydroergotamine mesylate developmental 6190-39-2 May 1, 1997

Dihydrosafrole cancer 94-58-6 January 1, 1988

Di-isodecyl phthalate (DIDP) developmental 68515-49-1/ April 20, 2007

26761-40-0

Diisopropyl sulfate cancer 2973-10-6 April 1, 1993

Diltiazem hydrochloride developmental 33286-22-5 February 27, 2001

3,3’-Dimethoxybenzidine cancer 119-90-4 January 1, 1988

 (o-Dianisidine)

3,3’-Dimethoxybenzidine cancer 20325-40-0 October 1, 1990 dihydrochloride

 (o-Dianisidine dihydrochloride)

3,3’-Dimethoxybenzidine-based cancer --- June 11, 2004 dyes metabolized to 3,3’- dimethoxybenzidine

N, N-Dimethylacetamide developmental 127-19-5 May 21, 2010

4-Dimethylaminoazobenzene cancer 60-11-7 January 1, 1988

trans-2-[(Dimethylamino)methyl- cancer 55738-54-0 January 1, 1988 imino]-5-[2-(5-nitro-2-furyl)vinyl]- 1,3,4-oxadiazole

7,12-Dimethylbenz(a)anthracene cancer 57-97-6 January 1, 1990

3,3’-Dimethylbenzidine cancer 119-93-7 January 1, 1988 (ortho-Tolidine)

-8- Proposition 65 List of Chemicals
3,3’-Dimethylbenzidine-based cancer --- June 11, 2004

 dyes metabolized to 3,3’-

 dimethylbenzidine

3,3’-Dimethylbenzidine cancer 612-82-8 April 1, 1992

 dihydrochloride

Dimethylcarbamoyl chloride cancer 79-44-7 January 1, 1988

1,1-Dimethylhydrazine (UDMH) cancer 57-14-7 October 1, 1989

1,2-Dimethylhydrazine cancer 540-73-8 January 1, 1988

2,6-Dimethyl-N-nitrosomorpholine cancer 1456-28-6 February 8, 2013

Dimethyl sulfate cancer 77-78-1 January 1, 1988

Dimethylvinylchloride cancer 513-37-1 July 1, 1989

Di-n-butyl phthalate (DBP) developmental, female, 84-74-2 December 2, 2005

male

Di-n-hexyl phthalate (DnHP) female, male 84-75-3 December 2, 2005

m-Dinitrobenzene male 99-65-0 July 1, 1990

o-Dinitrobenzene male 528-29-0 July 1, 1990

p-Dinitrobenzene male 100-25-4 July 1, 1990

3,7-Dinitrofluoranthene cancer 105735-71-5 August 26, 1997

3,9-Dinitrofluoranthene cancer 22506-53-2 August 26, 1997

1,3-Dinitropyrene cancer 75321-20-9 November 2, 2012

1,6-Dinitropyrene cancer 42397-64-8 October 1, 1990

1,8-Dinitropyrene cancer 42397-65-9 October 1, 1990

Dinitrotoluene (technical grade) female, male --- August 20, 1999

Dinitrotoluene mixture, 2,4-/2,6- cancer --- May 1, 1996

2,4-Dinitrotoluene cancer 121-14-2 July 1, 1988

2,4-Dinitrotoluene male 121-14-2 August 20, 1999

2,6-Dinitrotoluene cancer 606-20-2 July 1, 1995

2,6-Dinitrotoluene male 606-20-2 August 20, 1999

Dinocap developmental 39300-45-3 April 1, 1990

Dinoseb developmental, male 88-85-7 January 1, 1989

Di-n-propyl isocinchomeronate cancer 136-45-8 May 1, 1996

 (MGK Repellent 326)

1,4-Dioxane cancer 123-91-1 January 1, 1988

Diphenylhydantoin (Phenytoin) cancer 57-41-0 January 1, 1988

Diphenylhydantoin (Phenytoin) developmental 57-41-0 July 1, 1987

Diphenylhydantoin (Phenytoin), cancer 630-93-3 January 1, 1988

 sodium salt

Direct Black 38 (technical grade) cancer 1937-37-7 January 1, 1988

Direct Blue 6 (technical grade) cancer 2602-46-2 January 1, 1988

Direct Brown 95 (technical grade) cancer 16071-86-6 October 1, 1988

Disodium cyanodithioimido- developmental 138-93-2 March 30, 1999 carbonate

Disperse Blue 1 cancer 2475-45-8 October 1, 1990

Diuron cancer 330-54-1 May 31, 2002

Doxorubicin hydrochloride cancer 25316-40-9 July 1, 1987 (Adriamycin)

Doxorubicin hydrochloride developmental, male 25316-40-9 January 29, 1999 (Adriamycin)

Doxycycline (internal use) developmental 564-25-0 July 1, 1990

Doxycycline calcium (internal use) developmental 94088-85-4 January 1, 1992

Doxycycline hyclate (internal use) developmental 24390-14-5 October 1, 1991

Doxycycline monohydrate developmental 17086-28-1 October 1, 1991

-9- Proposition 65 List of Chemicals
 (internal use)

Endrin developmental 72-20-8 May 15, 1998

Environmental tobacco smoke developmental --- June 9, 2006 (ETS)

Epichlorohydrin cancer 106-89-8 October 1, 1987

Epichlorohydrin male 106-89-8 September 1, 1996

Epoxiconazole cancer 135319-73-2 April 15, 2011

Ergotamine tartrate developmental 379-79-3 April 1, 1990

Erionite cancer 12510-42-8/ October 1, 1988

66733-21-9

Estradiol 17B cancer 50-28-2 January 1, 1988

Estragole cancer 140-67-0 October 29, 1999

Estrogens, steroidal cancer --- August 19, 2005

Estrogen-progestogen (combined) cancer --- November 4, 2011 as menopausal therapy

Estrone cancer 53-16-7 January 1, 1988

Estropipate cancer, developmental 7280-37-7 August 26, 1997

Ethanol in alcoholic beverages cancer --- April 29, 2011

Ethinylestradiol cancer 57-63-6 January 1, 1988

Ethionamide developmental 536-33-4 August 26, 1997

Ethoprop cancer 13194-48-4 February 27, 2001

Ethyl acrylate cancer 140-88-5 July 1, 1989

Ethyl alcohol in alcoholic beverages developmental --- October 1, 1987

Ethylbenzene cancer 100-41-4 June 11, 2004

Ethyl-tert-butyl ether male 637-92-3 December 18, 2009

Ethyl dipropylthiocarbamate developmental 759-94-4 April 27, 1999

Ethyl-4,4’-dichlorobenzilate cancer 510-15-6 January 1, 1990

Ethylene dibromide cancer 106-93-4 July 1, 1987

Ethylene dibromide developmental, male 106-93-4 May 15, 1998

Ethylene dichloride (1,2- cancer 107-06-2 October 1, 1987 Dichloroethane)

Ethylene glycol monoethyl ether developmental, male 110-80-5 January 1, 1989

Ethylene glycol monoethyl developmental, male 111-15-9 January 1, 1993 ether acetate

Ethylene glycol monomethyl ether developmental, male 109-86-4 January 1, 1989

Ethylene glycol monomethyl developmental, male 110-49-6 January 1, 1993 ether acetate

Ethyleneimine (Aziridine) cancer 151-56-4 January 1, 1988

Ethylene oxide cancer 75-21-8 July 1, 1987

Ethylene oxide female 75-21-8 February 27, 1987

Ethylene oxide developmental, male 75-21-8 August 7, 2009

Ethylene thiourea cancer 96-45-7 January 1, 1988

Ethylene thiourea developmental 96-45-7 January 1, 1993

2-Ethylhexanoic acid developmental 149-57-5 August 7, 2009

Ethyl methanesulfonate cancer 62-50-0 January 1, 1988

Etodolac developmental, female 41340-25-4 August 20, 1999

Etoposide cancer 33419-42-0 November 4, 2011

Etoposide developmental 33419-42-0 July 1, 1990

Etoposide in combination with cancer --- November 4, 2011

 cisplatin and bleomycin

Etretinate developmental 54350-48-0 July 1, 1987

-10- Proposition 65 List of Chemicals
Fenoxaprop ethyl developmental 66441-23-4 March 26, 1999

Fenoxycarb cancer 72490-01-8 June 2, 2000

Filgrastim developmental 121181-53-1 February 27, 2001

Fluazifop butyl developmental 69806-50-4 November 6, 1998

Flunisolide developmental, female 3385-03-3 May 15, 1998

Fluorouracil developmental 51-21-8 January 1, 1989

Fluoxymesterone developmental 76-43-7 April 1, 1990

Flurazepam hydrochloride developmental 1172-18-5 October 1, 1992

Flurbiprofen developmental, female 5104-49-4 August 20, 1999

Flutamide developmental 13311-84-7 July 1, 1990

Fluticasone propionate developmental 80474-14-2 May 15, 1998

Fluvalinate developmental 69409-94-5 November 6, 1998

Folpet cancer 133-07-3 January 1, 1989

Formaldehyde (gas) cancer 50-00-0 January 1, 1988

2-(2-Formylhydrazino)-4- cancer 3570-75-0 January 1, 1988

 (5-nitro-2-furyl)thiazole

Fumonisin B1 cancer 116355-83-0 November 14, 2003

Furan cancer 110-00-9 October 1, 1993

Furazolidone cancer 67-45-8 January 1, 1990

Furmecyclox cancer 60568-05-0 January 1, 1990

Fusarin C cancer 79748-81-5 July 1, 1995

Gallium arsenide cancer 1303-00-0 August 1, 2008

Ganciclovir cancer, developmental, 82410-32-0 August 26, 1997

male

Ganciclovir sodium developmental, male 107910-75-8 August 26, 1997

Gasoline engine exhaust cancer --- October 1, 1990 (condensates/extracts)

Gemfibrozil cancer 25812-30-0 December 22, 2000

Gemfibrozil female, male 25812-30-0 August 20, 1999

Glass wool fibers cancer --- July 1, 1990 (inhalable and biopersistent)

Glu-P-1 (2-Amino-6-methyldipyrido cancer 67730-11-4 January 1, 1990 [1,2- a:3’,2’-d]imidazole)

Glu-P-2 (2-Aminodipyrido cancer 67730-10-3 January 1, 1990 [1,2-a:3’,2’-d]imidazole)

Glycidaldehyde cancer 765-34-4 January 1, 1988

Glycidol cancer 556-52-5 July 1, 1990

Goserelin acetate developmental, female, 65807-02-5 August 26, 1997

male

Griseofulvin cancer 126-07-8 January 1, 1990

Gyromitrin (Acetaldehyde cancer 16568-02-8 January 1, 1988 methylformylhydrazone)

Halazepam developmental 23092-17-3 July 1, 1990

Halobetasol propionate developmental 66852-54-8 August 20, 1999

Haloperidol developmental, female 52-86-8 January 29, 1999

Halothane developmental 151-67-7 September 1, 1996

HC Blue 1 cancer 2784-94-3 July 1, 1989

-11- Proposition 65 List of Chemicals
Heptachlor cancer 76-44-8 July 1, 1988

Heptachlor developmental 76-44-8 August 20, 1999

Heptachlor epoxide cancer 1024-57-3 July 1, 1988

Herbal remedies containing cancer --- July 9, 2004 plant species of the genus Aristolochia

Hexachlorobenzene cancer 118-74-1 October 1, 1987

Hexachlorobenzene developmental 118-74-1 January 1, 1989

Hexachlorobutadiene cancer 87-68-3 May 3, 2011

Hexachlorocyclohexane cancer --- October 1, 1987 (technical grade)

Hexachlorodibenzodioxin cancer 34465-46-8 April 1, 1988

Hexachloroethane cancer 67-72-1 July 1, 1990

2,4-Hexadienal (89% trans, trans cancer --- March 4, 2005

isomer; 11% cis, trans isomer)

Hexafluoroacetone male 684-16-2 August 1, 2008

Hexamethylphosphoramide cancer 680-31-9 January 1, 1988

Hexamethylphosphoramide male 680-31-9 October 1, 1994

Histrelin acetate developmental --- May 15, 1998

Hydramethylnon developmental, male 67485-29-4 March 5, 1999

Hydrazine cancer 302-01-2 January 1, 1988

Hydrazine sulfate cancer 10034-93-2 January 1, 1988

Hydrazobenzene cancer 122-66-7 January 1, 1988 (1,2-Diphenylhydrazine)

1-Hydroxyanthraquinone cancer 129-43-1 May 27, 2005

Hydroxyurea developmental 127-07-1 May 1, 1997

Idarubicin hydrochloride developmental, male 57852-57-0 August 20, 1999

Ifosfamide developmental 3778-73-2 July 1, 1990

Iodine-131 developmental 10043-66-0 January 1, 1989

Imazalil cancer 35554-44-0 May 20, 2011

Indeno[1,2,3-cd]pyrene cancer 193-39-5 January 1, 1988

Indium phosphide cancer 22398-80-7 February 27, 2001

IQ (2-Amino-3-methylimidazo cancer 76180-96-6 April 1, 1990 [4,5-f] quinoline)

Iprodione cancer 36734-19-7 May 1, 1996

Iprovalicarb cancer 140923-17-7 June 1, 2007

140923-25-7

Iron dextran complex cancer 9004-66-4 January 1, 1988

Isobutyl nitrite cancer 542-56-3 May 1, 1996

Isoprene cancer 78-79-5 May 1, 1996

Isopyrazam cancer 881685-58-1 July 24, 2012

Isosafrole Delisted cancer 120-58-1 October 1, 1989 December 8, 2006

Isotretinoin developmental 4759-48-2 July 1, 1987

Isoxaflutole cancer 141112-29-0 December 22, 2000

Kresoxim-methyl cancer 143390-89-0 February 3, 2012

Lactofen cancer 77501-63-4 January 1, 1989

Lasiocarpine cancer 303-34-4 April 1, 1988

Lead developmental, female, --- February 27, 1987

-12- Proposition 65 List of Chemicals
male

Lead and lead compounds cancer --- October 1, 1992

Lead acetate cancer 301-04-2 January 1, 1988

Lead phosphate cancer 7446-27-7 April 1, 1988

Lead subacetate cancer 1335-32-6 October 1, 1989

Leather dust cancer --- April 29, 2011

Leuprolide acetate developmental, female, 74381-53-6 August 26, 1997

male

Levodopa developmental 59-92-7 January 29, 1999

Levonorgestrel implants female 797-63-7 May 15, 1998

Lindane and other hexachloro- cancer --- October 1, 1989 cyclohexane isomers

Linuron developmental 330-55-2 March 19, 1999

Lithium carbonate developmental 554-13-2 January 1, 1991

Lithium citrate developmental 919-16-4 January 1, 1991

Lorazepam developmental 846-49-1 July 1, 1990

Lovastatin developmental 75330-75-5 October 1, 1992

Lynestrenol cancer 52-76-6 February 27, 2001

Malonaldehyde, sodium salt cancer 24382-04-5 May 3, 2011

Mancozeb cancer 8018-01-7 January 1, 1990

Maneb cancer 12427-38-2 January 1, 1990

Marijuana smoke cancer --- June 19, 2009

Me-A-alpha-C (2-Amino-3-methyl- cancer 68006-83-7 January 1, 1990 9H-pyrido[2,3-b]indole)

Mebendazole developmental 31431-39-7 August 20, 1999

Medroxyprogesterone acetate cancer 71-58-9 January 1, 1990

Medroxyprogesterone acetate developmental 71-58-9 April 1, 1990

Megestrol acetate developmental 595-33-5 January 1, 1991

MeIQ (2-Amino-3,4-dimethyl- cancer 77094-11-2 October 1, 1994 imidazo[4,5-f]quinoline)

MeIQx (2-Amino-3,8-dimethyl- cancer 77500-04-0 October 1, 1994 imidazo[4,5-f]quinoxaline)

Melphalan cancer 148-82-3 February 27, 1987

Melphalan developmental 148-82-3 July 1, 1990

Menotropins developmental 9002-68-0 April 1, 1990

Mepanipyrim cancer 110235-47-7 July 1, 2008

Meprobamate developmental 57-53-4 January 1, 1992

Mercaptopurine developmental 6112-76-1 July 1, 1990

Mercury and mercury compounds developmental --- July 1, 1990

Merphalan cancer 531-76-0 April 1, 1988

Mestranol cancer 72-33-3 April 1, 1988

Metam potassium cancer 137-41-7 December 31, 2010

Methacycline hydrochloride developmental 3963-95-9 January 1, 1991

Metham sodium cancer 137-42-8 November 6, 1998

Metham sodium developmental 137-42-8 May 15, 1998

Methanol developmental 67-56-1 March 16, 2012

Methazole developmental 20354-26-1 December 1, 1999

Methimazole developmental 60-56-0 July 1, 1990

Methotrexate developmental 59-05-2 January 1, 1989

Methotrexate sodium developmental 15475-56-6 April 1, 1990

-13- Proposition 65 List of Chemicals
5-Methoxypsoralen with cancer 484-20-8 October 1, 1988

 ultraviolet A therapy

8-Methoxypsoralen with cancer 298-81-7 February 27, 1987

 ultraviolet A therapy

2-Methylaziridine (Propyleneimine) cancer 75-55-8 January 1, 1988

Methylazoxymethanol cancer 590-96-5 April 1, 1988

Methylazoxymethanol acetate cancer 592-62-1 April 1, 1988

Methyl bromide, as a structural developmental 74-83-9 January 1, 1993

fumigant

Methyl carbamate cancer 598-55-0 May 15, 1998

Methyl chloride developmental 74-87-3 March 10, 2000

Methyl chloride male 74-87-3 August 7, 2009

3-Methylcholanthrene cancer 56-49-5 January 1, 1990

5-Methylchrysene cancer 3697-24-3 April 1, 1988

4,4'-Methylene bis(2-chloroaniline) cancer 101-14-4 July 1, 1987

4,4'-Methylene bis(N,N-dimethyl) cancer 101-61-1 October 1, 1989 benzenamine

4,4'-Methylene bis(2-methylaniline) cancer 838-88-0 April 1, 1988

4,4'-Methylenedianiline cancer 101-77-9 January 1, 1988

4,4'-Methylenedianiline cancer 13552-44-8 January 1, 1988

 dihydrochloride

Methyleugenol cancer 93-15-2 November 16, 2001

Methylhydrazine and its salts cancer --- July 1, 1992

2-Methylimidazole cancer 693-98-1 June 22, 2012

4-Methylimidazole cancer 822-36-6 January 7, 2011

Methyl iodide cancer 74-88-4 April 1, 1988

Methyl isobutyl ketone cancer 108-10-1 November 4, 2011

Methyl isocyanate (MIC) developmental, female 624-83-9 November 12, 2010

Methyl isopropyl ketone developmental 563-80-4 February 17, 2012

Methyl mercury developmental --- July 1, 1987

Methylmercury compounds cancer --- May 1, 1996

Methyl methanesulfonate cancer 66-27-3 April 1, 1988

Methyl n-butyl ketone male 591-78-6 August 7, 2009

2-Methyl-1-nitroanthraquinone cancer 129-15-7 April 1, 1988

 (of uncertain purity)

N-Methyl-N'-nitro-N- cancer 70-25-7 April 1, 1988

 nitrosoguanidine

N-Methylolacrylamide cancer 924-42-5 July 1, 1990

N-Methylpyrrolidone developmental 872-50-4 June 15, 2001

α-Methyl styrene (alpha- Methylstyrene)cancer 98-83-9 November 2, 2012

α-Methyl styrene female 98-83-9 July 29, 2011

Methyltestosterone developmental 58-18-4 April 1, 1990

Methylthiouracil cancer 56-04-2 October 1, 1989

Metiram cancer 9006-42-2 January 1, 1990

Metiram developmental 9006-42-2 March 30, 1999

Metronidazole cancer 443-48-1 January 1, 1988

Michler's ketone cancer 90-94-8 January 1, 1988

Midazolam hydrochloride developmental 59467-96-8 July 1, 1990

Minocycline hydrochloride developmental 13614-98-7 January 1, 1992 (internal use)

Mirex cancer 2385-85-5 January 1, 1988

-14- Proposition 65 List of Chemicals
Misoprostol developmental 59122-46-2 April 1, 1990

Mitomycin C cancer 50-07-7 April 1, 1988

Mitoxantrone hydrochloride developmental 70476-82-3 July 1, 1990

Molinate developmental, female, 2212-67-1 December 11, 2009

male

MON 4660 (dichloroacetyl-1- cancer 71526-07-3 March 22, 2011 oxa-4-azaspiro(4,5)-decane)

MON 13900 (furilazole) cancer 121776-33-8 March 22, 2011

3-Monochloropropane-1,2- cancer 96-24-2 October 8, 2010 diol (3-MCPD)

Monocrotaline cancer 315-22-0 April 1, 1988

5-(Morpholinomethyl)-3- cancer 139-91-3 April 1, 1988 [(5-nitrofurfuryl-idene)- amino]-2-oxazolidinone

MOPP (vincristine-prednisone- cancer 113803-47-7 November 4, 2011 nitrogen mustard-procarbazine mixture)

Mustard Gas cancer 505-60-2 February 27, 1987

MX (3-chloro-4-(dichloromethyl) cancer 77439-76-0 December 22, 2000 5-hydroxy-2(5H)-furanone)

Myclobutanil developmental, male 88671-89-0 April 16, 1999

Nabam developmental 142-59-6 March 30, 1999

Nafarelin acetate developmental 86220-42-0 April 1, 1990

Nafenopin cancer 3771-19-5 April 1, 1988

Nalidixic acid cancer 389-08-2 May 15, 1998

Naphthalene cancer 91-20-3 April 19, 2002

1-Naphthylamine cancer 134-32-7 October 1, 1989

2-Naphthylamine cancer 91-59-8 February 27, 1987

Neomycin sulfate (internal use) developmental 1405-10-3 October 1, 1992

Netilmicin sulfate developmental 56391-57-2 July 1, 1990

Nickel (Metallic) cancer 7440-02-0 October 1, 1989

Nickel acetate cancer 373-02-4 October 1, 1989

Nickel carbonate cancer 3333-67-3 October 1, 1989

Nickel carbonyl cancer 13463-39-3 October 1, 1987

Nickel carbonyl developmental 13463-39-3 September 1, 1996

Nickel compounds cancer --- May 7, 2004

Nickel hydroxide cancer 12054-48-7; 

12125-56-3

October 1, 1989

Nickelocene cancer 1271-28-9 October 1, 1989

Nickel oxide cancer 1313-99-1 October 1, 1989

Nickel refinery dust from the cancer --- October 1, 1987 pyrometallurgical process

Nickel subsulfide cancer 12035-72-2 October 1, 1987

Nicotine developmental 54-11-5 April 1, 1990

Nifedipine developmental, female, 21829-25-4 January 29, 1999

male

Nimodipine developmental 66085-59-4 April 24, 2001

Niridazole cancer 61-57-4 April 1, 1988

Nitrapyrin cancer 1929-82-4 October 5, 2005

Nitrapyrin developmental 1929-82-4 March 30, 1999

Nitrilotriacetic acid cancer 139-13-9 January 1, 1988

-15- Proposition 65 List of Chemicals
Nitrilotriacetic acid, trisodium cancer 18662-53-8 April 1, 1989

salt monohydrate

5-Nitroacenaphthene cancer 602-87-9 April 1, 1988

5-Nitro-o-anisidine Delisted December 8, 2006cancer 99-59-2 October 1, 1989

o-Nitroanisole cancer 91-23-6 October 1, 1992

Nitrobenzene cancer 98-95-3 August 26, 1997

Nitrobenzene male 98-95-3 March 30, 2010

4-Nitrobiphenyl cancer 92-93-3 April 1, 1988

6-Nitrochrysene cancer 7496-02-8 October 1, 1990

Nitrofen (technical grade) cancer 1836-75-5 January 1, 1988

2-Nitrofluorene cancer 607-57-8 October 1, 1990

Nitrofurantoin male 67-20-9 April 1, 1991

Nitrofurazone cancer 59-87-0 January 1, 1990

1-[(5-Nitrofurfurylidene)-amino]- cancer 555-84-0 April 1, 1988 2-imidazolidinone

N-[4-(5-Nitro-2-furyl)-2-thiazolyl] cancer 531-82-8 April 1, 1988

acetamide

Nitrogen mustard 

(Mechlorethamine)

cancer 51-75-2 January 1, 1988

Nitrogen mustard 

(Mechlorethamine)

developmental 51-75-2 January 1, 1989

Nitrogen mustard hydrochloride cancer 55-86-7 April 1, 1988 (Mechlorethamine hydrochloride)

Nitrogen mustard hydrochloride developmental 55-86-7 July 1, 1990 (Mechlorethamine hydrochloride)

Nitrogen mustard N-oxide cancer 126-85-2 April 1, 1988

Nitrogen mustard N-oxide cancer 302-70-5 April 1, 1988

hydrochloride

Nitromethane cancer 75-52-5 May 1, 1997

2-Nitropropane cancer 79-46-9 January 1, 1988

1-Nitropyrene cancer 5522-43-0 October 1, 1990

4-Nitropyrene cancer 57835-92-4 October 1, 1990

N-Nitrosodi-n-butylamine cancer 924-16-3 October 1, 1987

N-Nitrosodiethanolamine cancer 1116-54-7 January 1, 1988

N-Nitrosodiethylamine cancer 55-18-5 October 1, 1987

N-Nitrosodimethylamine cancer 62-75-9 October 1, 1987

p-Nitrosodiphenylamine cancer 156-10-5 January 1, 1988

N-Nitrosodiphenylamine cancer 86-30-6 April 1, 1988

N-Nitrosodi-n-propylamine cancer 621-64-7 January 1, 1988

N-Nitroso-N-ethylurea cancer 759-73-9 October 1, 1987

3-(N-Nitrosomethylamino)- cancer 60153-49-3 April 1, 1990 propionitrile

4-(N-Nitrosomethylamino)-1- cancer 64091-91-4 April 1, 1990 (3-pyridyl)1-butanone

N-Nitrosomethylethylamine cancer 10595-95-6 October 1, 1989

N-Nitroso-N-methylurea cancer 684-93-5 October 1, 1987

N-Nitroso-N-methylurethane cancer 615-53-2 April 1, 1988

N-Nitrosomethylvinylamine cancer 4549-40-0 January 1, 1988

N-Nitrosomorpholine cancer 59-89-2 January 1, 1988

N-Nitrosonornicotine cancer 16543-55-8 January 1, 1988

N-Nitrosopiperidine cancer 100-75-4 January 1, 1988

N-Nitrosopyrrolidine cancer 930-55-2 October 1, 1987

-16- Proposition 65 List of Chemicals
N-Nitrososarcosine cancer 13256-22-9 January 1, 1988

o-Nitrotoluene cancer 88-72-2 May 15, 1998

Nitrous oxide developmental 10024-97-2 August 1, 2008

Norethisterone (Norethindrone) cancer 68-22-4 October 1, 1989

Norethisterone (Norethindrone) developmental 68-22-4 April 1, 1990

Norethisterone acetate developmental 51-98-9 October 1, 1991 (Norethindrone acetate)

Norethisterone (Norethindrone) developmental 68-22-4/ April 1, 1990 /Ethinyl estradiol 57-63-6

Norethisterone developmental 68-22-4/ April 1, 1990 (Norethindrone)/Mestranol 72-33-3

Norethynodrel cancer 68-23-5 February 27, 2001

Norgestrel developmental 6533-00-2 April 1, 1990

Ochratoxin A cancer 303-47-9 July 1, 1990

Oil Orange SS cancer 2646-17-5 April 1, 1988

Oral contraceptives, combined cancer --- October 1, 1989

Oral contraceptives, sequential cancer --- October 1, 1989

Oryzalin cancer 19044-88-3 September 12, 2008

Oxadiazon cancer 19666-30-9 July 1, 1991

Oxadiazon developmental 19666-30-9 May 15, 1998

Oxazepam cancer 604-75-1 October 1, 1994

Oxazepam developmental 604-75-1 October 1, 1992

p,p’-Oxybis(benzenesulfonyl developmental 80-51-3 August 7, 2009 hydrazide)

Oxydemeton methyl female, male 301-12-2 November 6, 1998

Oxymetholone cancer 434-07-1 January 1, 1988

Oxymetholone developmental 434-07-1 May 1, 1997

Oxytetracycline (internal use) developmental 79-57-2 January 1, 1991

Oxytetracycline hydrochloride developmental 2058-46-0 October 1, 1991 (internal use)

Oxythioquinox (Chinomethionat) cancer 2439-01-2 August 20, 1999

Oxythioquinox (Chinomethionat) developmental 2439-01-2 November 6, 1998

Paclitaxel developmental, female, 33069-62-4 August 26, 1997

male

Palygorskite fibers (> 5μm in length) cancer 12174-11-7 December 28, 1999

Panfuran S cancer 794-93-4 January 1, 1988

Paramethadione developmental 115-67-3 July 1, 1990

Penicillamine developmental 52-67-5 January 1, 1991

Pentachlorophenol cancer 87-86-5 January 1, 1990

Pentobarbital sodium developmental 57-33-0 July 1, 1990

Pentostatin developmental 53910-25-1 September 1, 1996

Phenacemide developmental 63-98-9 July 1, 1990

Phenacetin cancer 62-44-2 October 1, 1989

Phenazopyridine cancer 94-78-0 January 1, 1988

Phenazopyridine hydrochloride cancer 136-40-3 January 1, 1988

Phenesterin cancer 3546-10-9 July 1, 1989

Phenobarbital cancer 50-06-6 January 1, 1990

Phenolphthalein cancer 77-09-8 May 15, 1998

Phenoxybenzamine cancer 59-96-1 April 1, 1988

-17- Proposition 65 List of Chemicals
Phenoxybenzamine hydrochloride cancer 63-92-3 April 1, 1988

Phenprocoumon developmental 435-97-2 October 1, 1992

o-Phenylenediamine and its salts cancer 95-54-5 May 15, 1998

Phenyl glycidyl ether cancer 122-60-1 October 1, 1990

Phenyl glycidyl ether male 122-60-1 August 7, 2009

Phenylhydrazine and its salts cancer --- July 1, 1992

o-Phenylphenate, sodium cancer 132-27-4 January 1, 1990

o-Phenylphenol cancer 90-43-7 August 4, 2000

Phenylphosphine developmental 638-21-1 August 7, 2009

PhiP(2-Amino-1-methyl-6- cancer 105650-23-5 October 1, 1994 phenylimidazol[4,5-b]pyridine)

Pimozide developmental, female 2062-78-4 August 20, 1999

Pipobroman developmental 54-91-1 July 1, 1990

Pirimicarb cancer 23103-98-2 July 1, 2008

Plicamycin developmental 18378-89-7 April 1, 1990

Polybrominated biphenyls cancer --- January 1, 1988

Polybrominated biphenyls developmental --- October 1, 1994

Polychlorinated biphenyls cancer --- October 1, 1989

Polychlorinated biphenyls developmental --- January 1, 1991

Polychlorinated biphenyls cancer --- January 1, 1988 (containing 60 or more percent

 chlorine by molecular weight)

Polychlorinated dibenzo-p-dioxins cancer --- October 1, 1992

Polychlorinated dibenzofurans cancer --- October 1, 1992

Polygeenan cancer 53973-98-1 January 1, 1988

Ponceau MX cancer 3761-53-3 April 1, 1988

Ponceau 3R cancer 3564-09-8 April 1, 1988

Potassium bromate cancer 7758-01-2 January 1, 1990

Potassium dimethyldithiocarbamate developmental 128-03-0 March 30 1999

Pravastatin sodium developmental 81131-70-6 March 3, 2000

Prednisolone sodium phosphate developmental 125-02-0 August 20, 1999

Primidone cancer 125-33-7 August 20, 1999

Procarbazine cancer 671-16-9 January 1, 1988

Procarbazine hydrochloride cancer 366-70-1 January 1, 1988

developmental July 1, 1990

Procymidone cancer 32809-16-8 October 1, 1994

Progesterone cancer 57-83-0 January 1, 1988

Pronamide cancer 23950-58-5 May 1, 1996

Propachlor cancer 1918-16-7 February 27, 2001

1,3-Propane sultone cancer 1120-71-4 January 1, 1988

Propargite cancer 2312-35-8 October 1, 1994

Propargite developmental 2312-35-8 June 15, 1999

beta-Propiolactone cancer 57-57-8 January 1, 1988

Propoxur cancer 114-26-1 August 11, 2006

Propylene glycol mono-t-butyl ether cancer 57018-52-7 June 11, 2004

Propylene oxide cancer 75-56-9 October 1, 1988

Propylthiouracil cancer 51-52-5 January 1, 1988

Propylthiouracil developmental 51-52-5 July 1, 1990

Pymetrozine cancer 1233112-89-0 March 22, 2011

Pyridine cancer 110-86-1 May 17, 2002

Pyrimethamine developmental 58-14-0 January 29, 1999

-18- Proposition 65 List of Chemicals
Quazepam developmental 36735-22-5 August 26, 1997

Quinoline and its strong acid salts cancer --- October 24, 1997

Quizalofop-ethyl male 76578-14-8 December 24, 1999

Radionuclides cancer --- July 1, 1989

Reserpine cancer 50-55-5 October 1, 1989

Residual (heavy) fuel oils cancer --- October 1, 1990

Resmethrin cancer 10453-86-8 July 1, 2008

Resmethrin developmental 10453-86-8 November 6, 1998

Retinol/retinyl esters, when in developmental --- July 1, 1989 daily dosages in excess of 10,000

 IU, or 3,000 retinol equivalents.

 (NOTE: Retinol/retinyl esters are

 required and essential for

 maintenance of normal reproductive function. 

 The recommended daily level

 during pregnancy is 8,000 IU.)

Ribavirin developmental 36791-04-5 April 1, 1990

Ribavirin male 36791-04-5 February 27, 2001

Riddelliine cancer 23246-96-0 December 3, 2004

Rifampin developmental, female 13292-46-1 February 27, 2001

Saccharin Delisted April 6, 2001 cancer 81-07-2 October 1, 1989

Saccharin, sodium cancer 128-44-9 January 1, 1988 Delisted January 17, 2003

Safrole cancer 94-59-7 January 1, 1988

Salted fish, Chinese-style cancer --- April 29, 2011

Secobarbital sodium developmental 309-43-3 October 1, 1992

Selenium sulfide cancer 7446-34-6 October 1, 1989

Sermorelin acetate developmental --- August 20, 1999

Shale-oils cancer 68308-34-9 April 1, 1990

Silica, crystalline (airborne particles cancer --- October 1, 1988

 of respirable size)

Sodium dimethyldithiocarbamate developmental 128-04-1 March 30 1999

Sodium fluoroacetate male 62-74-8 November 6, 1998

Soots, tars, and mineral oils cancer --- February 27, 1987

 (untreated and mildly treated oils

 and used engine oils)

Spirodiclofen cancer 148477-71-8 October 8, 2010

Spironolactone cancer 52-01-7 May 1, 1997

Stanozolol cancer 10418-03-8 May 1, 1997

Sterigmatocystin cancer 10048-13-2 April 1, 1988

Streptomycin sulfate developmental 3810-74-0 January 1, 1991

Streptozocin (streptozotocin) developmental, female, 18883-66-4 August 20, 1999

male

Streptozotocin (streptozocin) cancer 18883-66-4 January 1, 1988

Strong inorganic acid mists cancer --- March 14, 2003

 containing sulfuric acid

Styrene oxide cancer 96-09-3 October 1, 1988

Sulfallate cancer 95-06-7 January 1, 1988

-19- Proposition 65 List of Chemicals
Sulfasalazine cancer 599-79-1 May 15, 1998

 (salicylazosulfapyridine)

Sulfasalazine male 599-79-1 January 29, 1999

 (salicylazosulfapyridine)

Sulfur dioxide developmental 7446-09-5 July 29, 2011

Sulindac developmental, female 38194-50-2 January 29, 1999

Talc containing asbestiform fibers cancer --- April 1, 1990

Tamoxifen and its salts cancer 10540-29-1 September 1, 1996

Tamoxifen citrate developmental 54965-24-1 July 1, 1990

Temazepam developmental 846-50-4 April 1, 1990

Teniposide developmental 29767-20-2 September 1, 1996

Terbacil developmental 5902-51-2 May 18, 1999

Terrazole cancer 2593-15-9 October 1, 1994

Testosterone and its esters cancer 58-22-0 April 1, 1988

Testosterone cypionate developmental 58-20-8 October 1, 1991

Testosterone enanthate developmental 315-37-7 April 1, 1990

3,3′,4,4′-Tetrachloroazobenzene cancer 14047-09-7 July 24, 2012

2,3,7,8-Tetrachlorodibenzo-p- cancer 1746-01-6 January 1, 1988 dioxin (TCDD)

2,3,7,8-Tetrachlorodibenzo-p- developmental 1746-01-6 April 1, 1991 dioxin (TCDD)

1,1,2,2-Tetrachloroethane cancer 79-34-5 July 1, 1990

Tetrachloroethylene cancer 127-18-4 April 1, 1988 (Perchloroethylene)

p-a,a,a-Tetrachlorotoluene cancer 5216-25-1 January 1, 1990

Tetracycline (internal use) developmental 60-54-8 October 1, 1991

Tetracyclines (internal use) developmental --- October 1, 1992

Tetracycline hydrochloride developmental 64-75-5 January 1, 1991 (internal use)

Tetrafluoroethylene cancer 116-14-3 May 1, 1997

Tetranitromethane cancer 509-14-8 July 1, 1990

Thalidomide developmental 50-35-1 July 1, 1987

Thioacetamide cancer 62-55-5 January 1, 1988

4,4'-Thiodianiline cancer 139-65-1 April 1, 1988

Thiodicarb cancer 59669-26-0 August 20, 1999

Thioguanine developmental 154-42-7 July 1, 1990

Thiophanate methyl female, male 23564-05-8 May 18, 1999

Thiouracil cancer 141-90-2 June 11, 2004

Thiourea cancer 62-56-6 January 1, 1988

Thorium dioxide cancer 1314-20-1 February 27, 1987

Titanium dioxide (airborne, cancer --- September 2, 2011 unbound particles of

 respirable size)

Tobacco, oral use of cancer --- April 1, 1988

 smokeless products

Tobacco smoke cancer --- April 1, 1988

Tobacco smoke (primary) developmental, female, --- April 1, 1988

male

Tobramycin sulfate developmental 49842-07-1 July 1, 1990

Toluene developmental 108-88-3 January 1, 1991

Toluene female 108-88-3 August 7, 2009

-20- Proposition 65 List of Chemicals
Toluene diisocyanate cancer 26471-62-5 October 1, 1989

o-Toluidine cancer 95-53-4 January 1, 1988

o-Toluidine hydrochloride cancer 636-21-5 January 1, 1988

para-Toluidine cancer 106-49-0 January 1, 1990 Delisted October 29, 1999

Toxaphene (Polychlorinated cancer 8001-35-2 January 1, 1988 camphenes)

Toxins derived from Fusarium cancer --- August 7, 2009 Moniliforme (Fusarium verticillioides)

Treosulfan cancer 299-75-2 February 27, 1987

Triadimefon developmental, female, 43121-43-3 March 30, 1999

male

Triazolam developmental 28911-01-5 April 1, 1990

S,S,S-Tributyl phosphorotrithioate cancer 78-48-8 February 25, 2011 (Tribufos, DEF)

Tributyltin methacrylate developmental 2155-70-6 December 1, 1999

Trichlormethine (Trimustine cancer 817-09-4 January 1, 1992 hydrochloride)

Trichloroethylene cancer 79-01-6 April 1, 1988

2,4,6-Trichlorophenol cancer 88-06-2 January 1, 1988

1,2,3-Trichloropropane cancer 96-18-4 October 1,1992

Trientine hydrochloride developmental 38260-01-4 February 27, 2001

Triforine developmental 26644-46-2 June 18, 1999

1,3,5-Triglycidyl-s-triazinetrione male 2451-62-9 August 7, 2009

Trilostane developmental 13647-35-3 April 1, 1990

Trimethadione developmental 127-48-0 January 1, 1991

2,4,5-Trimethylaniline and cancer --- October 24, 1997

 its strong acid salts

Trimethyl phosphate cancer 512-56-1 May 1, 1996

Trimetrexate glucuronate developmental 82952-64-5 August 26, 1997

2,4,6-Trinitrotoluene cancer 118-96-7 December 19, 2008

Triphenyltin hydroxide cancer 76-87-9 July 1, 1992

Triphenyltin hydroxide developmental 76-87-9 March 18, 2002

Tris(aziridinyl)-p-benzoquinone cancer 68-76-8 October 1, 1989 (Triaziquone)

 Delisted December 8, 2006

Tris(1-aziridinyl)phosphine cancer 52-24-4 January 1, 1988

 sulfide (Thiotepa)

Tris(2-chloroethyl) phosphate cancer 115-96-8 April 1, 1992

Tris(2,3-dibromopropyl)phosphate cancer 126-72-7 January 1, 1988

Tris(1,3-dichloro-2-propyl) cancer 13674-87-8 October 28, 2011 phosphate (TDCPP)

Trp-P-1 (Tryptophan-P-1) cancer 62450-06-0 April 1, 1988

Trp-P-2 (Tryptophan-P-2) cancer 62450-07-1 April 1, 1988

Trypan blue (commercial grade) cancer 72-57-1 October 1, 1989

Unleaded gasoline (wholly cancer --- April 1, 1988 vaporized)

Uracil mustard cancer 66-75-1 April 1, 1988

developmental, female, January 1, 1992

male

-21- Proposition 65 List of Chemicals
Urethane (Ethyl carbamate) cancer 51-79-6 January 1, 1988

developmental October 1, 1994

Urofollitropin developmental 97048-13-0 April 1, 1990

Valproate (Valproic acid) developmental 99-66-1 July 1, 1987

Vanadium pentoxide (orthorhombic cancer 1314-62-1 February 11, 2005 crystalline form)

Vinblastine sulfate developmental 143-67-9 July 1, 1990

Vinclozolin cancer 50471-44-8 August 20, 1999

developmental May 15, 1998

Vincristine sulfate developmental 2068-78-2 July 1, 1990

Vinyl bromide cancer 593-60-2 October 1, 1988

Vinyl chloride cancer 75-01-4 February 27, 1987

4-Vinylcyclohexene cancer 100-40-3 May 1, 1996

4-Vinyl-cyclohexene female, male 100-40-3 August 7, 2009

4-Vinyl-1-cyclohexene diepoxide cancer 106-87-6 July 1, 1990

 (Vinyl cyclohexene dioxide)

Vinyl cyclohexene dioxide female, male 106-87-6 August 1, 2008 (4-Vinyl-1-cyclohexene diepoxide)

Vinyl fluoride cancer 75-02-5 May 1, 1997

Vinyl trichloride (1,1,2- cancer 79-00-5 October 1, 1990 Trichloroethane)

Warfarin developmental 81-81-2 July 1, 1987

Wood dust cancer --- December 18, 2009

2,6-Xylidine (2,6-Dimethylaniline) cancer 87-62-7 January 1, 1991

Zalcitabine cancer 7481-89-2 August 7, 2009

Zidovudine (AZT) cancer 30516-87-1 December 18, 2009

Zileuton cancer, developmental, 111406-87-2 December 22, 2000

female

Zineb Delisted October 29, 1999 cancer 12122-67-7 January 1, 1990

Date: February 8, 2013

-22- Proposition 65 List of Chemicals