58590 Federal Register / Vol. 88, No. 165 / Monday, August 28, 2023 / Notices 

must provide for an annual External 

Quality Review (EQR). The annual EQR 

is conducted by an independent 

external quality review organization 

(EQRO). States must provide the EQRO 

with information obtained through 

methods consistent with the protocols 

specified by CMS. The information is 

used by the EQRO to determine the 

quality of care furnished by the 

managed care plans in the state. The 

publicly posted EQR results allows 

Medicaid/CHIP enrollees and potential 

enrollees to make informed choices 

regarding the selection of their 

providers. It also provides advocacy 

organizations, researchers, and other 

interested parties access to information 

on the quality of care provided to 

Medicaid beneficiaries enrolled in 

Medicaid/CHIP managed care. States 

use the information during their 

oversight of these organizations. Form 

Number: CMS–R–305 (OMB control 

number: 0938–0786); Frequency: 

Annually and one-time; Affected Public: 

Private sector (business or other forprofits) and State, local or Tribal 

governments; Number of Respondents: 

698; Number of Responses: 10,249; 

Total Annual Hours: 483,784. (For 

policy questions regarding this 

collection contact Carlye Burd at 720– 

853–2780.) 

Dated: August 23, 2023. 

William N. Parham, III, 

Director, Paperwork Reduction Staff, Office 

of Strategic Operations and Regulatory 

Affairs. 

[FR Doc. 2023–18520 Filed 8–25–23; 8:45 am] 

BILLING CODE 4120–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

National Center for Advancing 

Translational Sciences; Notice of 

Closed Meeting 

Pursuant to section 1009 of the 

Federal Advisory Committee Act, as 

amended, notice is hereby given of the 

following meeting. 

The meeting will be closed to the 

public in accordance with the 

provisions set forth in sections 

552b(c)(4) and 552b(c)(6), title 5 U.S.C., 

as amended. The grant applications and 

the discussions could disclose 

confidential trade secrets or commercial 

property such as patentable material, 

and personal information concerning 

individuals associated with the grant 

applications, the disclosure of which 

would constitute a clearly unwarranted 

invasion of personal privacy. 

Name of Committee: National Center for 

Advancing Translational Sciences Special 

Emphasis Panel; NCATS SBIR Basket 

Clinical Trials. 

Date: September 21, 2023. 

Time: 11:30 a.m. to 3:00 p.m. 

Agenda: To review and evaluate grant 

applications. 

Place: National Institutes of Health, 

National Center for Advancing Translational 

Sciences, 6701 Democracy Boulevard, 

Bethesda, MD 20892 (Virtual Meeting). 

Contact Person: Nakia C Brown, Ph.D., 

Scientific Review Officer, Office of Grants 

Management and Scientific Review, National 

Center for Advancing Translational Sciences, 

National Institutes of Health, 6701 

Democracy Boulevard, Room 1037, Bethesda, 

MD 20892, (301) 827–3484, brownnac@

mail.nih.gov. 

(Catalogue of Federal Domestic Assistance 

Program Nos. 93.859, Pharmacology, 

Physiology, and Biological Chemistry 

Research; 93.350, B—Cooperative 

Agreements; 93.859, Biomedical Research 

and Research Training, National Institutes of 

Health, HHS) 

Dated: August 23, 2023. 

Melanie J. Pantoja, 

Program Analyst, Office of Federal Advisory 

Committee Policy. 

[FR Doc. 2023–18490 Filed 8–25–23; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

Government-Owned Inventions; 

Availability for Licensing 

AGENCY: National Institutes of Health, 

HHS. 

ACTION: Notice. 

SUMMARY: The invention listed below is 

owned by an agency of the U.S. 

Government and is available for 

licensing to achieve expeditious 

commercialization of results of 

federally-funded research and 

development. 

FOR FURTHER INFORMATION CONTACT: 

Licensing information may be obtained 

by communicating with Vidita 

Choudhry, Ph.D., Office of Technology 

Transfer and Development, National 

Heart, Lung, and Blood Institute, 31 

Center Drive Room 4A29, MSC2479, 

Bethesda, MD 20892–2479; telephone: 

301–594–4095; email: vidita.choudhry@

nih.gov. A signed Confidential 

Disclosure Agreement may be required 

to receive any unpublished information. 

SUPPLEMENTARY INFORMATION: 

Technology description follows. 

Apparatus for Cryogenic-Electron 

Microscopy Sample Preparation 

Cryo-Electron Microscopy (cryo-EM) 

is used to obtain high-resolution 

structural images of macromolecular 

structures. Samples must be purified 

and loaded onto cryo-EM grids before 

imaging. The ideal cryo-EM grid 

consists of particles that are evenly and 

richly distributed in a broad distribution 

of orientations throughout the holes of 

the support film. Current techniques to 

prepare cryo-EM grids are performed 

manually and require trial and error, 

resulting in a bottleneck in cryo-EM 

workflows. 

Researchers have developed a device 

and method for time-resolved 

preparation of liquid samples for cryoEM experiments. In particular, the 

mixing and dispensation of liquid 

samples is achieved by electrical signals 

that are transduced into specific 

acoustic frequencies to mix the liquid 

samples (low frequency) and then 

dispense the mixture (high frequency) 

in small, nanoliter volumes onto a cryoEM grid. This novel apparatus and 

method provides more precise control 

over liquid sample mixing and 

dispensing, and improved dispensation 

of the mixture onto the EM grid. Also, 

the improved quality of captured images 

of homogeneous macromolecular 

structures is achieved due to a 

uniformly mixed and dispensed sample 

on the EM grid. This allows electrons to 

be transmitted through the very thin 

liquid film in the holes of the cryo-EM 

grid to form an image. 

Potential Commercial Applications 

• Automation of cryo-EM 

experiments aimed at Structure-based 

Drug Design by examining 

macromolecular structure and its 

interactions with ligands. 

• Kits with hardware and software 

components to setup robotic automation 

of cryo-EM sample preparation, 

dispensation, plunging and storage. 

Competitive Advantages 

• Automated workflow eliminates the 

guesswork out of cryo-EM sample 

preparation. 

• Increases sample prep success rate 

and decreases the need to screen 

repeated trials. 

• Using acoustic-based, multiplesample mixing enables homogeneous 

mixing and facilitates the observation of 

transient molecular interactions with 

high time resolution. 

• Python code is available for 

command and control of a robot that 

manipulates the cryo-EM grid. 


lotter on DSK11XQN23PROD with NOTICES1
Federal Register / Vol. 88, No. 165 / Monday, August 28, 2023 / Notices 58591 

Development Stage 

• Prototype. 

Inventors 

Venkata M. Dandey (NIEHS), Mario J. 

Borgnia (NIEHS), Wyatt Peele (NIEHS), 

Tony J. Huang (Duke), and Kaichun 

Yang (Duke). 

Intellectual Property 

HHS Reference No. E–184–2023–0; 

U.S Provisional Patent Application 63/ 

472,113 filed June 09, 2023. 

Licensing Contact 

Vidita Choudhry, Ph.D.; 301–594– 

4095; vidita.choudhry@nih.gov. This 

notice is made in accordance with 35 

U.S.C. 209 and 37 CFR part 404. 

Dated: August 22, 2023. 

Vidita Choudhry, 

Senior Technology Transfer Manager, 

National Heart, Lung, and Blood Institute, 

Office of Technology Transfer and 

Development. 

[FR Doc. 2023–18438 Filed 8–25–23; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

Center for Scientific Review; Notice of 

Closed Meetings 

Pursuant to section 1009 of the 

Federal Advisory Committee Act, as 

amended, notice is hereby given of the 

following meetings. 

The meetings will be closed to the 

public in accordance with the 

provisions set forth in sections 

552b(c)(4) and 552b(c)(6), title 5 U.S.C., 

as amended. The grant applications and 

the discussions could disclose 

confidential trade secrets or commercial 

property such as patentable material, 

and personal information concerning 

individuals associated with the grant 

applications, the disclosure of which 

would constitute a clearly unwarranted 

invasion of personal privacy. 

Name of Committee: Center for Scientific 

Review Special Emphasis Panel; NIH 

Research Enhancement Award (R15) in 

Oncological Sciences. 

Date: September 20, 2023. 

Time: 9:00 a.m. to 7:00 p.m. 

Agenda: To review and evaluate grant 

applications. 

Place: National Institutes of Health, 

Rockledge II, 6701 Rockledge Drive, 

Bethesda, MD 20892 (Virtual Meeting). 

Contact Person: Byung Min Chung, Ph.D., 

Scientific Review Officer, Center for 

Scientific Review, National Institutes of 

Health, 6701 Rockledge Drive, Bethesda, MD 

20892, (301) 496–4056, justin.chung@

nih.gov. 

Name of Committee: Center for Scientific 

Review Special Emphasis Panel; PAR 22– 

104: Fogarty NCD–LIFESPAN Panel. 

Date: September 22, 2023. 

Time: 9:00 a.m. to 7:00 p.m. 

Agenda: To review and evaluate grant 

applications. 

Place: National Institutes of Health, 

Rockledge II, 6701 Rockledge Drive, 

Bethesda, MD 20892 (Virtual Meeting). 

Contact Person: Jeanne M McCaffery, 

Ph.D., Scientific Review Officer, Center for 

Scientific Review, 6701 Rockledge Drive, 

Bethesda, MD 20892, 301–594–3854, 

jeanne.mccaffery@nih.gov. 

(Catalogue of Federal Domestic Assistance 

Program Nos. 93.306, Comparative Medicine; 

93.333, Clinical Research, 93.306, 93.333, 

93.337, 93.393–93.396, 93.837–93.844, 

93.846–93.878, 93.892, 93.893, National 

Institutes of Health, HHS) 

Dated: August 23, 2023. 

Victoria E. Townsend, 

Program Analyst, Office of Federal Advisory 

Committee Policy. 

[FR Doc. 2023–18489 Filed 8–25–23; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

Eunice Kennedy Shriver National 

Institute of Child Health and Human 

Development; Notice of Closed 

Meetings 

Pursuant to section 1009 of the 

Federal Advisory Committee Act, as 

amended, notice is hereby given of the 

following meetings. 

The meetings will be closed to the 

public in accordance with the 

provisions set forth in sections 

552b(c)(4) and 552b(c)(6), title 5 U.S.C., 

as amended. The grant applications and 

the discussions could disclose 

confidential trade secrets or commercial 

property such as patentable material, 

and personal information concerning 

individuals associated with the grant 

applications, the disclosure of which 

would constitute a clearly unwarranted 

invasion of personal privacy. 

Name of Committee: Eunice Kennedy 

Shriver National Institute of Child Health 

and Human Development Special Emphasis 

Panel; Population Dynamics Centers 

Research Infrastructure Program FY 2024 

(P2C). 

Date: November 8–9, 2023. 

Time: 10:00 a.m. to 5:00 p.m. 

Agenda: To review and evaluate grant 

applications. 

Place: National Institutes of Health, Eunice 

Kennedy Shriver National Institute of Child 

Health and Human Development, 6710B 

Rockledge Drive, Room 2131D, Bethesda, MD 

20892 (Virtual Meeting). 

Contact Person: Anita Szajek, Ph.D., 

Scientific Review Officer, Scientific Review 

Branch, Eunice Kennedy Shriver National 

Institute of Child Health and Human 

Development, National Institutes of Health, 

6710B Rockledge Drive, Room 2131D, 

Bethesda, MD 20892, anita.szajek@nih.gov. 

Name of Committee: Eunice Kennedy 

Shriver National Institute of Child Health 

and Human Development Special Emphasis 

Panel; Opportunities for Advancing Limb 

Regeneration Research (R01). 

Date: November 17, 2023. 

Time: 10:00 a.m. to 5:00 p.m. 

Agenda: To review and evaluate grant 

applications. 

Place: National Institutes of Health, Eunice 

Kennedy Shriver National Institute of Child 

Health and Human Development, 6710B 

Rockledge Drive, Room 2131B, Bethesda, MD 

20892 (Virtual Meeting). 

Contact Person: Jolanta Maria Topczewska, 

Ph.D., Scientific Review Officer, Scientific 

Review Branch, Eunice Kennedy Shriver 

National Institute of Child Health and 

Human Development, National Institutes of 

Health, 6710B Rockledge Drive, Room 2131B, 

Bethesda, MD 20892, (301) 451–0000, 

jolanta.topczewska@nih.gov. 

(Catalogue of Federal Domestic Assistance 

Program Nos. 93.864, Population Research; 

93.865, Research for Mothers and Children, 

National Institutes of Health, HHS) 

Dated: August 23, 2023. 

Victoria E. Townsend, 

Program Analyst, Office of Federal Advisory 

Committee Policy. 

[FR Doc. 2023–18488 Filed 8–25–23; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

Coast Guard 

[Docket No. USCG–2011–0351] 

Consolidated Port Approaches Port 

Access Route Studies (CPAPARS) 

Final Notice 

AGENCY: Coast Guard, DHS. 

ACTION: Notification. 

SUMMARY: The Coast Guard published a 

document on March 10, 2023, that 

announced the availability of the final 

Consolidated Port Approaches Port 

Access Route Studies. In addition, the 

Coast Guard requested comments 

concerning the final report. After a 

review of the comments received, the 

Coast Guard has determined that it is 

not necessary to revise the final report, 

and therefore considers it to be 

complete as published. 

FOR FURTHER INFORMATION CONTACT: For 

information about this document call or 

email Maureen Kallgren, Coast Guard; 

telephone 202–372–1561, email 

maureen.r.kallgren2@uscg.mil. 

SUPPLEMENTARY INFORMATION: 


lotter on DSK11XQN23PROD with NOTICES1