# Patent

## Title
Pharmaceutical compositions

## Abstract

Compositions have been obtained by extracting rhizomes of Fagopyrum dibotrys with alcohol and concentrating the extract to a powder or syrup, optionally followed by fractionation. The extract is demonstrated to be a potent anti-cancer agent. Its activity at the gene level was analysed.

## Background
TECHNICAL FIELD
The present invention concerns compounds and compositions which are therapeutically active, e.g. against some types of cancer. Thus it provides compounds, compositions, methods of manufacturing compositions and methods of treatment. It is primarily concerned with pharmaceuticals derived from Fagopyrum dibotrys (or Fagopyrum cymosum meisen) (golden buckwheat; jinqiaomai).
BACKGROUND ART
Fagopyrum dibotrys is one of the innumerable plants used in Chinese traditional medicine. The whole plant, particularly the rhizome, is used as a medicament, allegedly having a wide range of beneficial effects, including antitumour activity.
Zhang Wen-Jie et al., Acta Botanica Yunnanica, 1994, 16, 354-356 separated and identified a number of phenolic constituents. The compound obtained in highest yield (0.19%) was termed procyanidin B-2 and was assigned the formula (1) (see FIG. 1). This compound has 5 asymmetric centres (asterisked in FIG. 1), so potentially there are 32 stereoisomers. No information is available about which isomer(s) is/are present in the isolated material. They are 5,7,3′,4′-tetrahydroxy flavon-3-1 C4-C8 dimers. Such a dimer or dimers was previously isolated from avocado seed (T. A. Geissmann et al. Phytochem., 1965, 4, 359-368).
DISCLOSURE OF INVENTION
We have now investigated materials derived from rhizomes of Fagopyrum dibotrys and have demonstrated remarkable and wholly unexpected levels of activity, notably against a number of cancers. Thus in various aspects the invention provides:
(a) the use of rhizomes of Fagopyrum dibotrys in the manufacture of a medicament for use in the treatment of cancer;
(b) the use of procyanidin B-2 as isolated from Fagopyrum dibotrys in the manufacture of a medicament for use in the treatment of cancer;
(c) the use of a compound of formula (1) in the manufacture of a medicament for use in the treatment of cancer;
(d) a process of producing a composition derived from rhizomes of Fagopyrum dibotrys suitable for use in cancer therapy;
(e) a method of cancer therapy comprising administration of a medicament which is a composition derived from rhyiomes of Fagopyrum dibotrys or procyanidin B-2 as isolated from Fagopyrum dibotrys. 
Material can be obtained from plant material by extraction with a lower (C1-C4) alcohol, preferably ethanol or methanol. This extract can be further purified by solvent extraction etc and by chromatography.
The material obtained from the plant or a compound isolated therefrom may be formulated in various ways for use in therapy. Conditions which may be treated include, for example, neoplastic diseases, particularly lung cancer and breast cancer. In accordance with this aspect of the present invention, the compounds provided may be administered to individuals. Administration is preferably in a “therapeutically effective amount”, this being sufficient to show benefit to a patient. Such benefit may be at least amelioration of at least one symptom. The actual amount administered, and rate and time-course of administration, will depend on the nature and severity of what is being treated. Prescription of treatment, e.g. decisions on dosage, is within the responsibility of general practitioners and other medical doctors.
A compound may be administered alone or in combination with other treatments, either simultaneously or sequentially dependent upon the condition to be treated.
Pharmaceutical compositions according to the present invention, and for use in accordance with the present invention, may comprise, in addition to the active ingredient, a pharmaceutically acceptable excipient, carrier, buffer, stabiliser or other materials well known to those skilled in the art. Such materials should be non-toxic and should not interfere with the efficacy of the active ingredient. The precise nature of the carrier or other material will depend on the route of administration, which may be oral, or by injection, e.g. cutaneous, subcutaneous, or intravenous.
Pharmaceutical compositions for oral administration may be in tablet, capsule, powder or liquid form. A tablet may comprise a solid carrier or an adjuvant. Liquid pharmaceutical compositions generally comprise a liquid carrier such as water, petroleum, animal or vegetable oils, mineral oil or synthetic oil. Physiological saline solution, dextrose or other saccharide solution or glycols such as ethylene glycol, propylene glycol or polyethylene glycol may be included. A capsule may comprise a solid carrier such a gelatin.
For intravenous, cutaneous or subcutaneous injection, or injection at the site of affliction, the active ingredient will be in the form of a parenterally acceptable aqueous solution which is pyrogen-free and has suitable pH, isotonicity and stability. Those of relevant skill in the art are well able to prepare suitable solutions using, for example, isotonic vehicles such as Sodium Chloride Injection, Ringer's Injection, Lactated Ringer's Injection. Preservatives, stabilisers, buffers, antioxidants and/or other additives may be included, as required.



BRIEF DESCRIPTION OF DRAWINGS
FIG. 1 shows the formula of procyanidin B-2.
FIGS. 2A and B are drawings of CT scans of a patient taken 3 months apart.
FIG. 3 is a graph showing activity in preventing the development of lung cancer.
FIG. 4 shows the results of flow cytometry experiments relating to anti-CD11b (cell surface marker for monocytes).
FIGS. 5-7 are graphs showing activity against breast cancer.
FIGS. 8-10 are graphs showing activity against lung cancer.
FIGS. 11 and 12 are pie charts giving a functional breakdown of up-regulated and down-regulated genes, respectively.



MODES FOR CARRYING OUT THE INVENTION
Production of Extract
Method A
Samples of Fagopyrum dibotrys were obtained from parts of China: Yun Nan Province; Long Quan District of Sichuan Province, Liang Shan District of Sichuan Province, and Chong Qing County of Sichuan Province. The material from Liang Shan appeared to be of the best quality and analysis showed it had by far the highest content of ketones (7.65% by weight), and a significantly higher tannin content (2.90% by weight). Therefore this material was used for further study.
Fagopyrum dibotrys rhizomes were broken into small particles, and 2400 kg of this particulate material was extracted with 70% ethanol 12 times using a total of 28,800 kg. The extract was concentrated by evaporation to give 1896 litres, 2184 kg. Half of this concentrate was further concentrated by evaporation under reduced pressure, which gave 278 kg of syrup. The other part was spray dried, which gave dry powder (80 kg). The syrup could be converted into a dry solid by heating in an oven. The solid could then be powdered.
The powder (spray or oven dried) contained 4.63% water, 35.35% ketones and 46.62% tannins, all by weight.
Method B
This is the result of further work on the development of a pilot plant.
1. Pre-Processing (Done in Sichuan Province, P.R.C)
1.1. Harvest the herb of Rhizoma Fagopyri Dibotryis, remove the stem and rootlet, clean and wash, dry at temperature below 60° C. to a moisture content of between 9% ̃13% (for an actual example, the moisture content was 11.97% prior to extraction).
1.2. Chop the dried clean herb into particulate to achieve the diameter of less than 2 mm.
2. Extraction of Herb
2.1 Using four 50 litre percolators, fill each percolator with 10 kg of the raw material.
2.2 Fill in 180 L 70% ethanol for the first time at 60° C. and the flow rate of 300 L/h. It took 12 h to macerate less than 60° C. Then make a circulation at 60° C. for 0.5 h. After that it took 15 minutes to discharge the liquid extract.
2.3 Fill in 300 L 70% ethanol for the second time at 60° C. and the flow rate of 300 L/h. Then it took 1 h to discharge the liquid extract.
3. Evaporation
Fill the evaporator with liquid extract, condense it at 50 ̃60° C. to the relative density at 1.06 ̃1.10 (50 ̃60° C.).
14.99 kg concentrated extract was obtained and employed for drying.
4. Vacuum Drying
Half of the concentrated extract (7.495 kg), was mixed with 0.565 kg maltodextrin and 0.055 kg colloidal anhydrous silica, then dried at 50 ̃60° C. in the vacuum oven for 6 h to the moisture content of 2.93%. A total of 2.53 kg dry material was obtained of which 20% is 0.506 kg excipient and 80% (2.024 kg) being the dry herbal extract.
Purification of Procyanidin B-2
Powder (2 kg) obtain by Method A was extracted with technical ethanol. After warming at 65° C. for 2 hrs, the solution was filtered. 13.2 g of mixture was obtained after removal of the solvent from the filtrate. The herb was macerated again overnight and warmed for 2 hrs at 65° C. and filtered. 8.2 g of brown residue was obtained from the second filtrate. TLC analysis of the two extractions showed that the constituents of them are essentially the same.
For the purification of Procyanidin B-2 with chromatography, we found that by using ETHYL ACETATE:ACETIC ACID:WATER=450:10:10 as eluent, most of the non-polar components could be removed. Three belts in the column were observed during the washing, the first one is green; the second one is red and the third one is brown. After the brown belt was washed down, Procyanidin B-2 was detected in the fractions collected. The relatively pure fractions were found to be suitable to view the component on TLC board, but not pure enough to run an NMR spectrum.
The detailed purification of Procyanidin B-2 on a column was carried out as follows: 100 g of the crude extract was dissolved in 1 L water with strong stirring. The dark solution was extracted twice with ethyl acetate (2×500 ml). A brown-glass (10.6 g) was obtained after removal of the solvent under vacuum. This step of purification could possibly remove most of the salts from the extraction.
120 g of silica gel was loaded into a column with hexane to reach the length of 60 cm. The brown glass (10.6 g) was dissolved in 15 ml ethyl acetate and added into the column. The column was washed with ETHYL ACETATE:ACETIC ACID:WATER=700:10:10 to get a mixture. In order to recover the silica gel, the column was washed with 500 ml water, followed by 500 ml methanol and then 500 ml ethyl acetate. The mixture obtained from the first run was loaded into this column again and eluted by the same solvent system. However, the fractions collected are still not pure enough. The 3.6 g mixture obtained was a pale yellow glass after being vacuum dried.
The mixture (3.6 g) was purified again by repeating the above mentioned procedures to get 0.29 g Procyanidin B-2. On TLC plate, its purity seems quite good. In its NMR spectrum, we could observe the resonances reported by Zhang et al. (op.cit.) but some impurities which cannot be identified are also present. Its Mass spectrum shows the molecular ion at m/z 577.2 ([M−H]) as the highest peak. Another peak at m/z 289.2 suggests that the fragment is the ion generated by breaking the C4-C8′′ bond of Procyanidin B-2.
An alternative method to purify Procyanidin B-2 is to elute the column with ethyl acetate/hexane as a gradient solvent system (increasing the volume ratio from 1/1 to 2.5/1) to remove most of the components that are less polar than Procyanidin B-2 (The washing is slow yet efficient). The mixture containing Procyanidin B-2 is collected and purified further with the first method.
The detailed spectroscopic data of Procyanidin B-2 are summarised as follow: UVλMeOH (1 gε): 208(4.96), 281(3.95); FAB-MS m/z: 577[M−H]−; 1H-NMR [(CD3)2CO]; δ2.73(1H, br, J=16.0 Hz), 2.89(1H, dd J=16.0, 4.0 Hz), 3.98 (1H, m), 4.32(1H, m), 4.71(1H, s), 4.98(1H, br), 5.05(1H, br), 5.93-6.03(3H, m), 6.64-6.96(6H, m).
Biological Activity
We have found that material extracted from Fagopyrum dibotrys possesses significant anti-tumour activity. In this study, it is named “MPCB”. It was found to inhibit the production of matrix metalloproteinases from tumour cells, particularly IV collagenases. We have found that the invasion of B16-BL6 melanoma cells through the basement membrane was inhibited by MPCB in a concentration-dependent manner. We also investigated the therapeutic effects of multiple oral administration of MPCB on mice inoculated with B16-BL6 melanoma cells. The administration of MPCB also significantly reduced the metastasis incidence as compared to untreated controls.
In a phase I study, 11 patients aged 11 to 78 with advanced NSCLC who have failed all conventional chemotherapy were given MPCB in escalated doses. This was in the form of soft-shell capsules containing the plant extract (powder) obtained by Method A above. Capsules were administered orally. The highest dose achieved was 7.2 grams daily (18 capsules, administered in 3 doses at different times) and no significant side-effects were encountered at this dose. Two of the 9 patients had stabilisation of disease, with a median survival of 9.5 months, instead of the expected median survival of 4 to 5 months for the entire group. In addition, the CEA level showed signficant reductions in some of the patients. In fact, there was significant reduction in tumour mass on CT scan evaluation of one of the patient.
FIGS. 2 A and B show CT scans of the patient taken 3 months apart. X indicates a lung, Y indicates the heart and Z indicates the aorta. The cancerous growth (lung cancer) is the unshaded area indicated by the arrow C. It can be seen that it is much reduced in the second scan.
In an acute toxic test of the drug on mice, the calculated LD50 is 61 g/kg; 95% confidence interval 48.73 g/kg to 77.02 g/kg. According to the standard physiology index ratio between mouse and human beings, the calculated LD50 is 183.78 g/man (60 kg); 95% confidence interval 146.19 to 213.06 g/man. Based on this result, the dosage of log/day is only 5.4% of the LD dosage. In addition, it was demonstrated that at low doses, as used in this study, indices such as WBC, Platelet, RBC, RDW and MCHC did not display significant changes. A sample of the drug was submitted to the Health Sciences Authority for analysis and no significant toxic compounds such as heavy metals were detected. The method of extraction and processing of the herb has received certification from the Sichuan Health Authorities.
Test were made of the purified B-2 compound on human breast cancer cells grown in tissue culture. A marked reduction in the number of cells in the treated samples was apparent.
The experiment was repeated using human liver cancer cells. Once again it was visually evident that the number of cancer cells was substantially reduced by the drug.
Tumour-Preventive Effects of MPCB
An ethanol extract prepared using the extract prepared by Method B was employed. The dried extract contained 20% excipients. It was ground, sieved, weighed and suspended in water with the final concentration of 0.20 g/ml (inclusive of excipients).
For in vivo experiments, 4-6 weeks female SCID mice weighing 15±4 g were used. 12 SCID mice, the control group, were given distilled water while 12 SCID mice in the test group were given 1.45 g/kg of the herbal extract per day. These mice were fed orally with 1.45 g/kg of the extract from day 0 to day 21.
At day 22, all mice were given a tumor challenge of 1×106 (200 μl of 5×106 cells/ml) of the human A549 lung cancer cells. The incidence of tumor take in these mice was followed.
Following the injection of the A549 cancer cells and till the end of the experiment, no behavioral and physiological abnormality was observed in both control and experimental groups. No mouse died during the experiment period. It was noted that all the SCID mice in the control group developed tumor. In comparison, only two out of twelve mice in the test group developed tumor (see graph, FIG. 3). In addition, the sizes of tumor of these two mice were much smaller than that of the mice in the control group (see graph below). The other 10 mice in the test group showed no sign of tumor.
Hence, we concluded that the ethanol extract of MPCB could prevent and retard the development of tumor.
The resistant to the development of cancer in SCID mice given MPCB is correlated with the reduction in CD11b+ cells (see FIG. 4). CD11b+ cells are known to produce peroxide radicals that associate with tumor promotion. Hence, the reduction in CD11b+ cells would support the observation that MPCB could prevent the development of human cancer in SCID mice. This effect is long lasting and the reduction in the CD11b+ cells could be demonstrated one month after the mice are no longer given MPCB.
Since MPCB can drastically decrease the number of monocytes, it is clear that it will be beneficial towards diseases resulting from or associated with inflammation.
Therapeutic Activity Against Breast Cancer
1×107 human MDA-231 breast cancer cells (200 μl of 2.5×107 cells/ml) were inoculated subcutaneously into 48 female SCID mice (4-6 weeks old, weight 15±4 g). In 8-14 days, the sizes of the tumor of the recipient mice ranged from 0.3-0.5 cm in diameter (when determined by vernier calipers). At this time, the mice were divided into four treatment groups as follows:
12 SCID mice were given distilled water (control group);
12 SCID mice were given 1.45 g/kg (1⁄5 LD50) of the MPCB extract (Test group 1);
12 SCID mice-were given 0.84 g/kg of the MPCB extract (Test group 2);
12 SCID mice were given 0.39 g/kg of the MPCB extract (Test group 3).
MPCB herbal-extract as used in the preceding experiment (aqueous suspension, 0.20 g/ml) was administrated orally to the SCID mice and the development of tumor was recorded.
Following the injection of the MDA-231 human breast cancer cells till the end of the experiment, no behavioral and physiological abnormality was observed in both the control and test groups.
It was observed that in comparison to the control group of which the tumor developed progressively, tumor growth in all the three test groups of which the tumor-bearing SCID mice were-given the MPCB extract, the rate of tumor growth was much reduced. The data are presented in FIGS. 5-7. Hence, it was therefore concluded that MPCB has a therapeutic effect towards the growth of human breast cancer in the SCID mice model.
Therapeutic Activity Against Lung Cancer
1×106 human A549 lung cancer cells (200 μl of 5×106 cells/ml) were inoculated subcutaneously into 48 female SCID mice (4-6 weeks old, weight 15±4 g). In 8-14 days, the sizes of the tumor of the recipient mice ranged from 0.3-0.5 cm in diameter (when determined by vernier calipers). At this time, the mice were divided into four treatment groups as follows:
12 SCID mice were given distilled water (control group);
12 SCID mice were given 1.45 g/kg (1⁄5 LD50) of the MPCB extract (Test group 1);
12 SCID mice were given 0.84 g/kg of the MPCB extract (Test group 2);
12 SCID mice were given 0.39 g/kg of the MPCB extract (Test group 3).
MPCB herbal extract as used in the previous experiments (aqueous suspension, 0.20 g/ml) was administrated orally to the SCID mice and the development of tumor was recorded.
Following the injection of the A549 human lung cancer cells till the end of the experiment, no behavioral and physiological abnormality was observed in both the control and test groups.
It was observed that in comparison to the control group of which the tumor developed progressively, tumor growth in all the three test groups of which the tumor-bearing SCID mice were given the MPCB extract, the rate of tumor growth was much reduced (see FIGS. 8-10). Hence, it was therefore concluded that MPCB has a therapeutic effect towards the growth of human lung cancer in the SCID mice model.
Gene Activity
The mechanism of action at the gene level was investigated using Affymetrix gene chips. Tables 1-4 list genes up-regulated at days 2 and 5, and down-regulated at days 2 and 5.
Human A549 lung cancer cells in SCID mice were treated with the MPCB extract. These genes are differentially up-regulated or down-regulated after subtracting out their level of expression in untreated tumor cells. We have classified these genes according to their reported functions (see FIGS. 11 and 12). This information allows one to easily formulate the roles of these genes in the various known biochemical pathways. For example, when 16 of the most highly up-regulated and down-regulated differentially expressed genes are employed, they could be fitted into various known pathways. In additional, when we fit some of these genes into one of the reported pathways for oncogenesis, we could demonstrate that many of these genes are down-regulate. All these data support strongly the anti-oncolytic function of the MPCB extract.







TABLE 1







genes up-regulated at day 2








Gene Name
Gene Description





200000_s_at
PRP8 pre-mRNA processing factor 8 homolog (yeast)


200023_s_at
eukaryotic translation initiation factor 3, subunit 5



(epsilon, 47 kD)


200044_at
splicing factor, arginine/serine-rich 9


200047_s_at
YY1 transcription factor


200055_at
TAF10 RNA polymerase II, TATA box binding protein (TBP)-



associated factor, 30 kD


200069_at
squamous cell carcinoma antigen recognised by T cells 3


200071_at
sin3-associated polypeptide, 18 kD


200083_at
ubiquitin specific protease 22


31874_at
growth arrest-specific 2 like 1


32032_at
clathrin, heavy polypeptide-like 1 [BLAST]


32137_at
jagged 2


33132_at
cleavage and polyadenylation specific factor 1, 160 kD



subunit


33322_i_at
stratifin


34764_at
activity-dependent neuroprotector


36553_at
acetylserotonin O-methyltransferase-like


37462_i_at
splicing factor 3a, subunit 2, 66 kD


37652_at
ribosomal protein L13a


38157_at
dom-3 homolog Z (C. elegans)


39248_at
aquaporin 3


39729_at
peroxiredoxin 2 [BLAST]


39835_at
SET binding factor 1


40465_at
fatty acid desaturase 2


40472_at
peroxisomal farnesylated protein


41047_at
chromosome 9 open reading frame 16


41858_at
RAB30, member RAS oncogene family [BLAST]


44111_at
vacuolar protein sorting 33B (yeast)


44654_at
ribosomal protein S4-like 2


44696_at
protocadherin beta 17 pseudogene


44783_s_at
hairy/enhancer-of-split related with YRPW motif 1


46665_at
sema domain, immunoglobulin domain (Ig), transmembrane



domain (TM) and short cytoplasmic domain, (semaphorin) 4C


47069_at
Rho GTPase activating protein 8


47083_at
prion protein interacting protein


50314_i_at
chromosome 20 open reading frame 27


52164_at
chromosome 11 open reading frame 24


53071_s_at
hypothetical protein FLJ22222


59625_at
nucleolar protein 3 (apoptosis repressor with CARD



domain)


55872_at
solute carrier family 12, (potassium-chloride



transporter) member 5


60474_at
chromosome 20 open reading frame 42


64474_g_at
RNA binding motif protein 15


65884_at
mannosidase, alpha, class 1B, member 1


91703_at
integrin, beta 1 (fibronectin receptor, beta polypeptide,



antigen CD29 includes MDF2, MSK12)


91816_f_at
CUB and Sushi multiple domains 1


200593_s_at
gb: BC003621.1 /DEF = Homo sapiens, heterogeneous nuclear



ribonucleoprotein U (scaffold attachment factor A), clone MGC: 1992,



mRNA, complete cds. /FEA = mRNA /PROD = heterogeneous nuclear



ribonucleopro . . .


200618_at
LIM and SH3 protein 1


200619_at
splicing factor 3b, subunit 2, 145 kD


200623_s_at
calmodulin 3 (phosphorylase kinase, delta)


200637_s_at
protein tyrosine phosphatase, receptor type, F


200655_s_at
calmodulin 1 (phosphorylase kinase, delta)


200675_at
CD81 antigen (target of antiproliferative antibody 1)


200702_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 24 [BLAST]


200707_at
protein kinase C substrate 80K-H


200710_at
acyl-Coenzyme A dehydrogenase, very long chain


200743_s_at
ceroid-lipofuscinosis, neuronal 2, late infantile



(Jansky-Bielschowsky disease)


200747_s_at
nuclear mitotic apparatus protein 1


200766_at
cathepsin D (lysosomal aspartyl protease)


200768_s_at
methionine adenosyltransferase II, alpha


200810_s_at
cold inducible RNA binding protein


200811_at
cold inducible RNA binding protein


200816_s_at
platelet-activating factor acetylhydrolase, isoform Ib,



alpha subunit (45 kD)


200827_at
procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine



hydroxylase, Ehlers-Danlos syndrome type VI)


200864_s_at
RAB11A, member RAS oncogene family


200867_at
zinc finger protein 313


200875_s_at
nucleolar protein 5A (56 kD with KKE/D repeat)


200884_at
creatine kinase, brain


200891_s_at
signal sequence receptor, alpha (translocon-associated



protein alpha)


200899_s_at
meningioma expressed antigen 5 (hyaluronidase)


200903_s_at
S-adenosylhomocysteine hydrolase


200914_x_at
kinectin 1 (kinesin receptor)


200918_s_at
signal recognition particle receptor (‘docking protein’)


200950_at
actin related protein 2/3 complex, subunit 1A (41 kD)


200959_at
fusion, derived from t(12;16) malignant liposarcoma


200965_s_at
actin binding LIM protein


200967_at
peptidylprolyl isomerase B (cyclophilin B)


200968_s_at
peptidylprolyl isomerase B (cyclophilin B)


200980_s_at
pyruvate dehydrogenase (lipoamide) alpha 1


200990_at
gb: NM_005762.1 /DEF = Homo sapiens KRAB-associated protein



1 (TIF1B), mRNA. /FEA = mRNA /GEN = TIF1B /PROD = KRAB-associated protein 1



/DB_XREF = gi: 5032178 /UG = Hs.228059 KRAB-associated protein 1 /FL = gb: B



. . .


201003_x_at
gb: NM_003349.2 /DEF = Homo sapiens ubiquitin-conjugating



enzyme E2 variant 1 (UBE2V1), transcript variant 2, mRNA. /FEA = mRNA



/GEN = UBE2V1 /PROD = ubiquitin-conjugating enzyme E2 variant 1, isoform b



/ . . .


201008_s_at
thioredoxin interacting protein


201011_at
ribophorin I


201015_s_at
junction plakoglobin


201024_x_at
Consensus includes gb: BG261322 /FEA = EST



/DB_XREF = gi: 12771138 /DB_XREF = est: 602373079F1 /CLONE = IMAGE: 4484563



/UG = Hs.158688 KIAA0741 gene product /FL = gb: AB018284.1 gb: AF078035.1



gb: NM_015904.1


201034_at
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain


201037_at
phosphofructokinase, platelet


201052_s_at
proteasome (prosome, macropain) inhibitor subunit 1



(PI31)


201054_at
heterogeneous nuclear ribonucleoprotein A0 [BLAST]


201064_s_at
poly(A) binding protein, cytoplasmic 4 (inducible form)


201065_s_at
general transcription factor II, i [BLAST]


201074_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily c, member 1


201079_at
synaptogyrin 2


201082_s_at
dynactin 1 (p150, glued homolog, Drosophila)


201102_s_at
phosphofructokinase, liver


201113_at
Tu translation elongation factor, mitochondrial


201128_s_at
ATP citrate lyase


201129_at
gb: NM_006276.2 /DEF = Homo sapiens splicing factor,



arginineserine-rich 7 (35 kD) (SFRS7), mRNA. /FEA = mRNA /GEN = SFRS7



/PROD = splicing factor, arginineserine-rich 7 (35 kD)



/DB_XREF = gi: 6857827 /UG = Hs. . . .


201160_s_at
cold shock domain protein A


201161_s_at
cold shock domain protein A


201176_s_at
archain 1


201183_s_at
chromodomain helicase DNA binding protein 4


201188_s_at
inositol 1,4,5-triphosphate receptor, type 3


201189_s_at
inositol 1,4,5-triphosphate receptor, type 3


201190_s_at
phosphotidylinositol transfer protein


201198_s_at
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1


201209_at
histone deacetylase 1


201225_s_at
serine/arginine repetitive matrix 1


201244_s_at
v-raf-1 murine leukemia viral oncogene homolog 1


201247_at
sterol regulatory element binding transcription factor 2


201255_x_at
HLA-B associated transcript 3


201264_at
coatomer protein complex, subunit epsilon


201271_s_at
RNA binding protein (autoantigenic, hnRNP-associated with



lethal yellow)


201296_s_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 1


201310_s_at
Kruppel-like factor 4 (gut)


201313_at
gb: NM_001975.1 /DEF = Homo sapiens enolase 2, (gamma,



neuronal) (ENO2), mRNA. /FEA = mRNA /GEN = ENO2 /PROD = enolase 2, (gamma,



neuronal) /DB_XREF = gi: 5803010 /UG = Hs.146580 enolase 2, (gamma,



neuronal) / . . .


201315_x_at
interferon induced transmembrane protein 2 (1-8D)


201331_s_at
signal transducer and activator of transcription 6,



interleukin-4 induced


201356_at
splicing factor 3a, subunit 1, 120 kD


201360_at
cystatin C (amyloid angiopathy and cerebral hemorrhage)


201362_at
polymerase (RNA) III (DNA directed) polypeptide F (39 kD)


201363_s_at
polymerase (RNA) III (DNA directed) polypeptide F (39 kD)


201373_at
plectin 1, intermediate filament binding protein, 500 kD


201377_at
synaptosomal-associated protein, 91 kD homolog (mouse)


201379_s_at
tumor protein D52-like 2


201393_s_at
insulin-like growth factor 2 receptor


201413_at
hydroxysteroid (17-beta) dehydrogenase 4


201440_at
fatty acid desaturase 2


201448_at
TIA1 cytotoxic granule-associated RNA binding protein


201454_s_at
Consensus includes gb: AW055008 /FEA = EST



/DB_XREF = gi: 5920711 /DB_XREF = est: wy98c09.x1 /CLONE = IMAGE: 2556592



/UG = Hs.293007 aminopeptidase puromycin sensitive /FL = gb: NM_006310.1


201459_at
RuvB-like 2 (E. coli)


201482_at
quiescin Q6


201489_at
peptidylprolyl isomerase F (cyclophilin F)


201498_at
ubiquitin specific protease 7 (herpes virus-associated)


201526_at
ADP-ribosylation factor 5


201545_s_at
poly(A) binding protein, nuclear 1


201555_at
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)


201564_s_at
singed-like (fascin homolog, sea urchin) (Drosophila)


201569_s_at
POM121 membrane glycoprotein-like 1 (rat)


201585_s_at
splicing factor proline/glutamine rich (polypyrimidine



tract binding protein associated)


201598_s_at
inositol polyphosphate phosphatase-like 1


201612_at
aldehyde dehydrogenase 9 family, member A1


201618_x_at
GPAA1P anchor attachment protein 1 homolog (yeast)


201620_at
membrane-bound transcription factor protease, site 1


201623_s_at
aspartyl-tRNA synthetase


201624_at
aspartyl-tRNA synthetase


201639_s_at
cleavage and polyadenylation specific factor 1, 160 kD



subunit


201641_at
bone marrow stromal cell antigen 2


201643_x_at
chromosome 5 open reading frame 7


201645_at
tenascin C (hexabrachion)


201650_at
keratin 19


201669_s_at
myristoylated alanine-rich protein kinase C substrate


201670_s_at
myristoylated alanine-rich protein kinase C substrate


201675_at
A kinase (PRKA) anchor protein 1


201679_at
tripartite motif-containing 33


201689_s_at
tumor protein D52


201690_s_at
tumor protein D52


201697_s_at
DNA (cytosine-5-)-methyltransferase 1


201704_at
ectonucleoside triphosphate diphosphohydrolase 6



(putative function)


201714_at
tubulin, gamma 1


201719_s_at
erythrocyte membrane protein band 4.1-like 2


201726_at
ELAV (embryonic lethal, abnormal vision, Drosophila)-like



1 (Hu antigen R)


201746_at
tumor protein p53 (Li-Fraumeni syndrome)


201747_s_at
scaffold attachment factor B


201790_s_at
7-dehydrocholesterol reductase


201795_at
lamin B receptor


201818_at
brain and acute leukemia, cytoplasmic


201828_x_at
CAAX box 1


201833_at
histone deacetylase 2


201841_s_at
heat shock 27 kD protein 1


201853_s_at
cell division cycle 25B


201885_s_at
diaphorase (NADH) (cytochrome b-5 reductase)


201889_at
family with sequence similarity 3, member C


201928_at
plakophilin 4


201937_s_at
aspartyl aminopeptidase


201970_s_at
nuclear autoantigenic sperm protein (histone-binding)


202039_at
TGFB1-induced anti-apoptotic factor 1


202043_s_at
spermine synthase


202060_at
Rho guanine nucleotide exchange factor (GEF) 10


202066_at
protein tyrosine phosphatase, receptor type, f



polypeptide (PTPRF), interacting protein (liprin), alpha 1


202097_at
nucleoporin 153 kD


202104_s_at
spastic paraplegia 7, paraplegin (pure and complicated



autosomal recessive)


202106_at
golgi autoantigen, golgin subfamily a, 3


202115_s_at
ATP-binding cassette, sub-family A (ABC1), member 12


202117_at
Rho GTPase activating protein 1


202119_s_at
copine III


202127_at
myotubularin related protein 2


202130_at
sudD suppressor of bimD6 homolog (A. nidulans)


202136_at
S-adenosylhomocysteine hydrolase-like 1


202139_at
aldo-keto reductase family 7, member A2 (aflatoxin



aldehyde reductase)


202151_s_at
CD2 antigen (cytoplasmic tail) binding protein 2


202159_at
phenylalanine-tRNA synthetase-like


202161_at
protein kinase C-like 1


202171_at
zinc finger protein 161


202173_s_at
zinc finger protein 161


202180_s_at
major vault protein


202182_at
GCN5 general control of amino-acid synthesis 5-like 2



(yeast)


202189_x_at
polypyrimidine tract binding protein 1 [BLAST]


202219_at
solute carrier family 6 (neurotransmitter transporter,



creatine), member 8


202220_at
calsyntenin 1


202227_s_at
jumping translocation breakpoint


202228_s_at
dynein, axonemal, intermediate polypeptide 1


202230_s_at
calcium homeostasis endoplasmic reticulum protein


202240_at
polo-like kinase (Drosophila)


202241_at
growth differentiation factor 11


202251_at
PRP4 pre-mRNA processing factor 4 homolog (yeast)


202275_at
glucose-6-phosphate dehydrogenase


202289_s_at
transforming, acidic coiled-coil containing protein 2


202308_at
sterol regulatory element binding transcription factor 1


202320_at
general transcription factor IIIC, polypeptide 1 (alpha



subunit, 220 kD)


202344_at
heat shock transcription factor 1


202357_s_at
B-factor, properdin [BLAST]


202384_s_at
Treacher Collins-Franceschetti syndrome 1


202424_at
mitogen-activated protein kinase kinase 2


202430_s_at
phospholipid scramblase 1


202446_s_at
phospholipid scramblase 1


202464_s_at
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3


202478_at
immunoglobulin kappa joining 1


202510_s_at
tumor necrosis factor, alpha-induced protein 2


202534_x_at
dihydrofolate reductase


202536_at
EGF-like-domain, multiple 6


202540_s_at
3-hydroxy-3-methylglutaryl-Coenzyme A reductase


202561_at
tankyrase, TRF1-interacting ankyrin-related ADP-ribose



polymerase


202569_s_at
MAP/microtubule affinity-regulating kinase 3


202580_x_at
forkhead box M1


202589_at
thymidylate synthetase


202605_at
glucuronidase, beta


202686_s_at
AXL receptor tyrosine kinase


202715_at
carbamoyl-phosphate synthetase 2, aspartate



transcarbamylase, and dihydroorotase


202718_at
insulin-like growth factor binding protein 2 (36 kD)


202757_at
rotatin


202804_at
ATP-binding cassette, sub-family C (CFTR/MRP), member 1


202809_s_at
down-regulated in colon cancer 1


202812_at
glucosidase, alpha; acid (Pompe disease, glycogen storage



disease type II)


202836_s_at
mannosidase, alpha, class 1A, member 2


202853_s_at
RYK receptor-like tyrosine kinase


202870_s_at
CDC20 cell division cycle 20 homolog (S. cerevisiae)


202890_at
Consensus includes gb: AW242297 /FEA = EST



/DB_XREF = gi: 6576051 /DB_XREF = est: xm96b11.x1 /CLONE = IMAGE: 2692029



/UG = Hs.146388 microtubule-associated protein 7 /FL = gb: NM_003980.1


202917_s_at
S100 calcium binding protein A8 (calgranulin A)


202929_s_at
D-dopachrome tautomerase


202934_at
hexokinase 2 [BLAST]


202936_s_at
SRY (sex determining region Y)-box 9 (campomelic



dysplasia, autosomal sex-reversal)


202951_at
serine/threonine kinase 38


202962_at
kinesin family member 13B


202979_s_at
ras homolog gene family, member U


202998_s_at
lysyl oxidase-like 2


203021_at
secretory leukocyte protease inhibitor



(antileukoproteinase) [BLAST]


203062_s_at
heparan sulfate 2-O-sulfotransferase 1


203065_s_at
caveolin 1, caveolae protein, 22 kD [BLAST]


203067_at
cysteine and glycine-rich protein 3 (cardiac LIM protein)


203098_at
chromodomain protein, Y chromosome-like


203102_s_at
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-



acetylglucosaminyltransferase


203103_s_at
HIV TAT specific factor 1


203108_at
retinoic acid induced 3


203109_at
ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)


203124_s_at
solute carrier family 11 (proton-coupled divalent metal



ion transporters), member 2


203126_at
inositol(myo)-1(or 4)-monophosphatase 2


203137_at
M-phase phosphoprotein 1


203153_at
interferon-induced protein with tetratricopeptide repeats 1


203155_at
SET domain, bifurcated 1


203156_at
A kinase (PRKA) anchor protein 11


203184_at
fibrillin 2 (congenital contractural arachnodactyly)


203189_s_at
NADH dehydrogenase (ubiquinone) Fe—S protein 8 (23 kD)



(NADH-coenzyme Q reductase)


203195_s_at
nucleoporin 98 kD


203198_at
cyclin-dependent kinase 9 (CDC2-related kinase) [BLAST]


203219_s_at
adenine phosphoribosyltransferase


203224_at
chromosome 20 open reading frame 38


203234_at
uridine phosphorylase


203244_at
peroxisome receptor 1


203252_at
gb: NM_005851.1 /DEF = Homo sapiens tumor suppressor deleted



in oral cancer-related 1 (DOC-1R), mRNA. /FEA = mRNA /GEN = DOC-1R



/PROD = tumor suppressor deleted in oral cancer-related1



/DB_XREF = gi: 503166 . . .


203262_s_at
DNA segment on chromosome X (unique) 9928 expressed



sequence


203276_at
lamin B1


203282_at
glucan (1,4-alpha-), branching enzyme 1 (glycogen



branching enzyme, Andersen disease, glycogen storage disease type IV)


203286_at
Rho-related BTB domain containing 3


203338_at
protein phosphatase 2, regulatory subunit B (B56),



epsilon isoform


203386_at
chromosome 21 open reading frame 108


203391_at
gb: NM_004470.1 /DEF = Homo sapiens FK506-binding protein 2



(13 kD) (FKBP2), mRNA. /FEA = mRNA /GEN = FKBP2 /PROD = FK506-binding



protein 2 (13 kD) /DB_XREF = gi: 4758381 /UG = Hs.227729 FK506-binding



protein 2 . . .


203417_at
microfibrillar-associated protein 2


203439_s_at
stanniocalcin 2


203477_at
collagen, type XV, alpha 1


203482_at
zinc finger protein 334


203495_at
syndecan 3 (N-syndecan)


203564_at
Fanconi anemia, complementation group G


203612_at
bystin-like [BLAST]


203683_s_at
vascular endothelial growth factor B


203690_at
ariadne homolog 2 (Drosophila)


203701_s_at
chromosome 20 open reading frame 13


203739_at
zinc finger protein 217


203767_s_at
steroid sulfatase (microsomal), arylsulfatase C, isozyme S


203775_at
solute carrier family 25, member 13 (citrin)


203802_x_at
LUC7-like (S. cerevisiae)


203818_s_at
splicing factor 3a, subunit 3, 60 kD


203825_at
bromodomain containing 3


203828_s_at
zinc finger protein 206


203831_at
[BLAST]


203848_at
A kinase (PRKA) anchor protein 8


203867_s_at
toll interacting protein


203919_at
transcription elongation factor A (SII), 2


203955_at
GRB2-associated binding protein 2


203974_at
synapsin III


203976_s_at
chromatin assembly factor 1, subunit A (p150)


204022_at
abhydrolase domain containing 1


204030_s_at
schwannomin interacting protein 1


204058_at
malic enzyme 1, NADP(+)-dependent, cytosolic


204133_at
cyclin E2


204142_at
SRY (sex determining region Y)-box 6


204143_s_at
SRY (sex determining region Y)-box 6


204178_s_at
RNA binding motif protein 14


204224_s_at
GTP cyclohydrolase 1 (dopa-responsive dystonia)


204238_s_at
secretagogin, EF-hand calcium binding protein


204274_at
Consensus includes gb: AA812215 /FEA = EST



/DB_XREF = gi: 2881826 /DB_XREF = est: ob84g01.s1 /CLONE = IMAGE: 1338096



/UG = Hs.9222 estrogen receptor binding site associated, antigen, 9



/FL = gb: BC005249.1 gb: AF0 . . .


204275_at
small optic lobes homolog (Drosophila)


204295_at
surfeit 1


204367_at
Sp2 transcription factor


204372_s_at
KH-type splicing regulatory protein (FUSE binding protein



2)


204383_at
clathrin, heavy polypeptide-like 1


204401_at
potassium intermediate/small conductance calcium-



activated channel, subfamily N, member 4


204409_s_at
eukaryotic translation initiation factor 1A, Y chromosome


204480_s_at
chromosome 9 open reading frame 16


204520_x_at
bromodomain containing 1


204521_at
cleavage and polyadenylation specific factor 1, 160 kD



subunit


204531_s_at
breast cancer 1, early onset


204584_at
L1 cell adhesion molecule (hydrocephalus, stenosis of



aqueduct of Sylvius 1, MASA (mental retardation, aphasia, shuffling



gait and adducted thumbs) syndrome, spastic paraplegia 1)


204617_s_at
aquaporin 9


204641_at
NIMA (never in mitosis gene a)-related kinase 2


204698_at
interferon stimulated gene (20 kD)


204717_s_at
solute carrier family 29 (nucleoside transporters),



member 2


204805_s_at
H1 histone family, member X


204808_s_at
transmembrane protein 5


204839_at
membrane-bound transcription factor protease, site 2


204849_at
transcription factor-like 5 (basic helix-loop-helix)


204857_at
MAD1 mitotic arrest deficient-like 1 (yeast)


204858_s_at
endothelial cell growth factor 1 (platelet-derived)


204875_s_at
GDP-mannose 4,6-dehydratase


204908_s_at
B-cell CLL/lymphoma 3


205000_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y



chromosome


205053_at
primase, polypeptide 1 (49 kD)


205068_s_at
paternally expressed 10


205081_at
cysteine-rich protein 1 (intestinal)


205155_s_at
spectrin, beta, non-erythrocytic 2


205199_at
carbonic anhydrase IX


205202_at
protein-L-isoaspartate (D-aspartate) O-methyltransferase


205353_s_at
prostatic binding protein


205382_s_at
D component of complement (adipsin)


205412_at
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl



Coenzyme A thiolase)


205436_s_at
H2A histone family, member X


205449_at
cleavage and polyadenylation specific factor 1, 160 kD



subunit


205501_at
phosphodiesterase 10A


205516_x_at
neuronal guanine nucleotide exchange factor


205527_s_at
gem (nuclear organelle) associated protein 4


205534_at
BH-protocadherin (brain-heart) [BLAST]


205546_s_at
tyrosine kinase 2


205552_s_at
2′,5′-oligoadenylate synthetase 1 (40-46 kD)


205565_s_at
Friedreich ataxia


205583_s_at
NIMA (never in mitosis gene a)-related kinase 11


205640_at
aldehyde dehydrogenase 3 family, member B1


205658_s_at
small nuclear RNA activating complex, polypeptide 4,



190 kD


205780_at
BCL2-interacting killer (apoptosis-inducing)-


205961_s_at
gb: NM_004682.1 /DEF = Homo sapiens PC4 and SFRS1



interacting protein 2 (PSIP2), mRNA. /FEA = mRNA /GEN = PSIP2 /PROD = PC4



and SFRS1 interacting protein 2 /DB_XREF = gi: 4758869 /UG = Hs.306179 PC4



and SFRS1 . . .


205967_at
H4 histone family, member G


206023_at
neuromedin U


206095_s_at
gb: NM_006625.2 /DEF = Homo sapiens TLS-associated serine-



arginine protein 1 (TASR1), mRNA. /FEA = mRNA /GEN = TASR1 /PROD = TLS-



associated serine-arginine protein 1 /DB_XREF = gi: 12056474



/UG = Hs.288038 TL . . .


206102_at
tripartite motif-containing 14


206200_s_at
annexin A11


206332_s_at
interferon, gamma-inducible protein 16


206499_s_at
chromosome condensation 1


206785_s_at
killer cell lectin-like receptor subfamily C, member 2


206809_s_at
heterogeneous nuclear ribonucleoprotein A3


207002_s_at
pleiomorphic adenoma gene-like 1


207076_s_at
argininosuccinate synthetase [BLAST]


207122_x_at
sulfotransferase family, cytosolic, 1A, phenol-



preferring, member 2


207140_at
alkaline phosphatase, intestinal


207165_at
hyaluronan-mediated motility receptor (RHAMM)


207169_x_at
discoidin domain receptor family, member 1


207170_s_at
ribosomal protein L36


207196_s_at
UDP-Gal: betaGlcNAc beta 1,3-galactosyltransferase,



polypeptide 5


207414_s_at
paired basic amino acid cleaving system 4


207564_x_at
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-



acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)


207622_s_at
ATP-binding cassette, sub-family F (GCN20), member 2


207714_s_at
serine (or cysteine) proteinase inhibitor, clade H (heat



shock protein 47), member 1, (collagen binding protein 1)


207723_s_at
killer cell lectin-like receptor subfamily C, member 3


207760_s_at
nuclear receptor co-repressor 2


207761_s_at
component of oligomeric golgi complex 4


207824_s_at
MYC-associated zinc finger protein (purine-binding



transcription factor)


207831_x_at
deoxyhypusine synthase


207842_s_at
zyxin [BLAST]


207847_s_at
mucin 1, transmembrane


208072_s_at
diacylglycerol kinase, delta (130 kD)


208132_x_at
HLA-B associated transcript 2


208149_x_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-



like helicase homolog, S. cerevisiae) [BLAST]


208156_x_at
gb: NM_031308.1 /DEF = Homo sapiens epiplakin 1 (EPPK1),



mRNA. /FEA = mRNA /GEN = EPPK1 /PROD = epiplakin 1 /DB_XREF = gi: 13876385



/FL = gb: NM_031308.1


208159_x_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-



like helicase homolog, S. cerevisiae)


208248_x_at
amyloid beta (A4) precursor-like protein 2


208270_s_at
arginyl aminopeptidase (aminopeptidase B)


208313_s_at
splicing factor 1


208336_s_at
glycoprotein, synaptic 2


208407_s_at
catenin (cadherin-associated protein), delta 1


208436_s_at
interferon regulatory factor 7


208617_s_at
protein tyrosine phosphatase type IVA, member 2


208621_s_at
villin 2 (ezrin)


208625_s_at
eukaryotic translation initiation factor 4 gamma, 1


208636_at
actinin, alpha 1


208647_at
farnesyl-diphosphate farnesyltransferase 1


208655_at
cyclin I


208676_s_at
chromosome 20 open reading frame 54


208700_s_at
transketolase (Wernicke-Korsakoff syndrome)


208703_s_at
amyloid beta (A4) precursor-like protein 2


208704_x_at
amyloid beta (A4) precursor-like protein 2


208705_s_at
5′-nucleotidase, cytosolic IA


208706_s_at
5′-nucleotidase, cytosolic IA


208713_at
protein tyrosine phosphatase, non-receptor type 21


208714_at
NADH dehydrogenase (ubiquinone) flavoprotein 1 (51 kD)


208719_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72 kD)


208729_x_at
major histocompatibility complex, class I, B


208773_s_at
baculoviral IAP repeat-containing 6 (apollon)


208774_at
casein kinase 1, delta


208788_at
transgene insertion 2, Craig B Thompson


208794_s_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily a, member 4


208798_x_at
F-box only protein 21


208804_s_at
splicing factor, arginine/serine-rich 6


208809_s_at
gb: AL136632.1 /DEF = Homo sapiens mRNA; cDNA DKFZp564G182



(from clone DKFZp564G182); complete cds. /FEA = mRNA /GEN = DKFZp564G182



/PROD = hypothetical protein /DB_XREF = gi: 12052789 /UG = Hs.173685 hypothe



. . .


208820_at
PTK2 protein tyrosine kinase 2


208858_s_at
WD repeat domain 7


208863_s_at
splicing factor, arginine/serine-rich 1 (splicing factor



2, alternate splicing factor)


208880_s_at
chromosome 20 open reading frame 14


208890_s_at
plexin B2


208891_at
dual specificity phosphatase 6


208892_s_at
dual specificity phosphatase 6


208906_at
ligand of numb-protein X


208912_s_at
gb: BC001362.1 /DEF = Homo sapiens, 2,3-cyclic nucleotide 3



phosphodiesterase, clone MGC: 2262, mRNA, complete cds. /FEA = mRNA



/PROD = 2,3-cyclic nucleotide 3 phosphodiesterase /DB_XREF = gi: 12655028



/UG . . .


208923_at
cytoplasmic FMR1 interacting protein 1


208928_at
P450 (cytochrome) oxidoreductase


208930_s_at
interleukin enhancer binding factor 3, 90 kD


208931_s_at
interleukin enhancer binding factor 3, 90 kD


208938_at
papillary renal cell carcinoma (translocation-associated)


208968_s_at
aldo-keto reductase family 1, member B10 (aldose



reductase)


208978_at
cysteine-rich protein 2


208984_x_at
RNA binding motif protein 10


208988_at
F-box and leucine-rich repeat protein 11


208998_at
uncoupling protein 2 (mitochondrial, proton carrier)


209007_s_at
solute carrier family 17 (sodium-dependent inorganic



phosphate cotransporter), member 7


209029_at
COP9 constitutive photomorphogenic homolog subunit 7A



(Arabidopsis)


209044_x_at
splicing factor 3b, subunit 4, 49 kD


209052_s_at
Wolf-Hirschhorn syndrome candidate 1


209053_s_at
Wolf-Hirschhorn syndrome candidate 1


209054_s_at
Wolf-Hirschhorn syndrome candidate 1


209075_s_at
bromodomain containing 4


209112_at
cyclin-dependent kinase inhibitor 1B (p27, Kip1)


209118_s_at
platelet-activating factor acetylhydrolase, isoform Ib,



pseudogene 1


209120_at
nuclear receptor subfamily 2, group F, member 2


209128_s_at
squamous cell carcinoma antigen recognised by T cells 3


209153_s_at
transcription factor 3 (E2A immunoglobulin enhancer



binding factors E12/E47)


209156_s_at
collagen, type VI, alpha 2


209215_at
glycoprotein A33 (transmembrane)


209228_x_at
zinc finger protein 212


209236_at
solute carrier family 23 (nucleobase transporters),



member 1


209262_s_at
nuclear receptor subfamily 2, group F, member 6


209263_x_at
transmembrane 4 superfamily member 7


209264_s_at
transmembrane 4 superfamily member 7


209265_s_at
thioredoxin interacting protein


209289_at
nuclear factor I/B


209290_s_at
nuclear factor I/B


209295_at
tumor necrosis factor receptor superfamily, member 10b


209318_x_at
pleiomorphic adenoma gene-like 1


209332_s_at
MAX protein


209337_at
gb: AF063020.1 /DEF = Homo sapiens lens epithelium-derived



growth factor mRNA, complete cds. /FEA = mRNA /PROD = lens epithelium-



derived growth factor /DB_XREF = gi: 3283351 /UG = Hs.82110 PC4 and SFRS1



int . . .


209341_s_at
inhibitor of kappa light polypeptide gene enhancer in B-



cells, kinase beta


209407_s_at
deformed epidermal autoregulatory factor 1 (Drosophila)


209409_at
growth factor receptor-bound protein 10


209449_at
chromosome 6 open reading frame 28


209496_at
retinoic acid receptor responder (tazarotene induced) 2


209505_at
nuclear receptor subfamily 2, group F, member 1


209581_at
HRAS-like suppressor 3


209607_x_at
sulfotransferase family, cytosolic, 1A, phenol-



preferring, member 3


209623_at
methylcrotonoyl-Coenzyme A carboxylase 2 (beta) [BLAST]


209630_s_at
G protein-coupled receptor 37 (endothelin receptor type



B-like)


209675_s_at
protein tyrosine phosphatase, non-receptor type 21


209723_at
serine (or cysteine) proteinase inhibitor, clade B



(ovalbumin), member 9


209729_at
growth arrest-specific 2 like 1


209754_s_at
thymopoietin


209759_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 37


209784_s_at
jagged 2


209832_s_at
carcinoembryonic antigen-related cell adhesion molecule 1


209873_s_at
plakophilin 3


209899_s_at
DnaJ (Hsp40) homolog, subfamily C, member 8 [BLAST]


210010_s_at
solute carrier family 25 (mitochondrial carrier; citrate



transporter), member 1


210026_s_at
succinate dehydrogenase complex, subunit D, integral



membrane protein pseudogene 1


210028_s_at
origin recognition complex, subunit 3-like (yeast)


210069_at
carnitine palmitoyltransferase I, muscle


210105_s_at
FYN oncogene related to SRC, FGR, YES


210111_s_at
G protein-coupled receptor 61


210150_s_at
laminin, alpha 5


210208_x_at
HLA-B associated transcript 3


210336_x_at
zinc finger protein 42 (myeloid-specific retinoic acid-



responsive)


210337_s_at
ATP citrate lyase


210371_s_at
retinoblastoma binding protein 4


210410_s_at
mutS homolog 5 (E. coli)


210428_s_at
hepatocyte growth factor-regulated tyrosine kinase



substrate


210448_s_at
purinergic receptor P2X, ligand-gated ion channel, 5


210802_s_at
serine protease inhibitor, Kazal type 4


210878_s_at
chromosome 5 open reading frame 7


210891_s_at
general transcription factor II, i


211052_s_at
tubulin-specific chaperone d [BLAST]


211060_x_at
GPAA1P anchor attachment protein 1 homolog (yeast)



[BLAST]


211065_x_at
phosphofructokinase, liver [BLAST]


211075_s_at
gb: Z25521.1 /DEF = H. sapiens integrin associated protein



mRNA, complete CDS,. /FEA = mRNA /PROD = integrin associated protein



/DB_XREF = gi: 396704 /FL = gb: Z25521.1


211270_x_at
polypyrimidine tract binding protein 1


211284_s_at
granulin


211300_s_at
tumor protein p53 (Li-Fraumeni syndrome)


211358_s_at
neuronal guanine nucleotide exchange factor


211375_s_at
interleukin enhancer binding factor 3, 90 kD


211385_x_at
sulfotransferase family, cytosolic, 1A, phenol-



preferring, member 2


211529_x_at
HLA-G histocompatibility antigen, class I, G


211564_s_at
KH-type splicing regulatory protein (FUSE binding protein



2)


211596_s_at
1(3)mbt-like (Drosophila) [BLAST]


211618_s_at
gb: M31008.1 /DEF = Human intestinal alkaline phosphatase



mRNA, complete cds. /FEA = mRNA /GEN = ALPI /DB_XREF = gi: 178443



/FL = gb: M31008.1


211678_s_at
maternally expressed 3 [BLAST]


211929_at
heterogeneous nuclear ribonucleoprotein A3


211967_at
F-box only protein 32 [BLAST]


211986_at
AHNAK nucleoprotein (desmoyokin)


212005_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 1


212015_x_at
polypyrimidine tract binding protein 1 [BLAST]


212028_at
proline dehydrogenase (oxidase) 2


212030_at
proline dehydrogenase (oxidase) 2


212032_s_at
prostate tumor over expressed gene 1 [BLAST]


212033_at
proline dehydrogenase (oxidase) 2


212037_at
pinin, desmosome associated protein


212056_at
MDN1, midasin homolog (yeast)


212062_at
ATPase, Class II, type 9A


212067_s_at
Consensus includes gb: AL573058 /FEA = EST



/DB_XREF = gi: 12931931 /DB_XREF = est: AL573058 /CLONE = CS0DI014YC05 (3



prime) /UG = Hs.1279 complement component 1, r subcomponent


212068_s_at
ATPase, Class V, type 10B


212069_s_at
ATPase, Class V, type 10B


212089_at
lamin A/C


212124_at
retinoic acid induced 17


212126_at
regulator of G-protein signalling 8


212137_at
ATP synthase mitochondrial F1 complex assembly factor 2


212139_at
GCN1 general control of amino-acid synthesis 1-like 1



(yeast)


212159_x_at
adaptor-related protein complex 2, alpha 2 subunit


212170_at
RNA binding motif protein 12


212179_at
SAM domain and HD domain, 1


212186_at
acetyl-Coenzyme A carboxylase alpha


212203_x_at
interferon induced transmembrane protein 3 (1-8U)-


212206_s_at
opsin 4 (melanopsin) [BLAST]


212218_s_at
F-box only protein 9 [BLAST]


212231_at
F-box only protein 21


212251_at
nuclear autoantigenic sperm protein (histone-binding)



[BLAST]


212269_s_at
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)



associated protein


212285_s_at
agrin


212300_at
Consensus includes gb: AL049795 /DEF = Human DNA sequence



from clone RP4-622L5 on chromosome 1p34.2-36.11. Contains the gene



for importin alpha 7 (karyopherin), up to six novel genes and the 5



end o . . .


212307_s_at
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-



acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)


212316_at
Rho-related BTB domain containing 2


212319_at
synaptosomal-associated protein, 91 kD homolog (mouse)


212361_s_at
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2



[BLAST]


212396_s_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 2


212403_at
solute carrier family 25 (mitochondrial oxodicarboxylate



carrier), member 21 [BLAST]


212408_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 1


212414_s_at
capicua homolog (Drosophila)


212429_s_at
general transcription factor IIIC, polypeptide 2 (beta



subunit, 110 kD)


212456_at
chromosome 21 open reading frame 80


212493_s_at
chromosome 20 open reading frame 30


212498_at
brain-specific angiogenesis inhibitor 3 [BLAST]


212499_s_at
collagen, type II, alpha 1 (primary osteoarthritis,



spondyloepiphyseal dysplasia, congenital) [BLAST]


212520_s_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily a, member 4


212547_at
Consensus includes gb: N34842 /FEA = EST /DB_XREF = gi: 1155984



/DB_XREF = est: yy45d11.s1 /CLONE = IMAGE: 276501 /UG = Hs.6580 Homo sapiens



cDNA: FLJ23227 fis, clone CAE00645, highly similar to AF052138 Homo



. . .


212561_at
ATPase, Class VI, type 11A


212563_at
block of proliferation 1


212566_at
ret finger protein 2


212589_at
related RAS viral (r-ras) oncogene homolog 2


212612_at
REST corepressor


212630_at
chromobox homolog 3 (HP1 gamma homolog, Drosophila)


212643_at
collagen, type II, alpha 1 (primary osteoarthritis,



spondyloepiphyseal dysplasia, congenital) [BLAST]


212644_s_at
collagen, type II, alpha 1 (primary osteoarthritis,



spondyloepiphyseal dysplasia, congenital) [BLAST]


212647_at
related RAS viral (r-ras) oncogene homolog


212685_s_at
Consensus includes gb: AI608789 /FEA = EST



/DB_XREF = gi: 4617956 /DB_XREF = est: tw94g12.x1 /CLONE = IMAGE: 2267398



/UG = Hs.52515 transducin (beta)-like 2


212691_at
SH3-domain GRB2-like endophilin B2 [BLAST]


212693_at
MDN1, midasin homolog (yeast)


212747_at
chromosome 17 open reading frame 31 [BLAST]


212752_at
cytoplasmic linker associated protein 1


212761_at
transcription factor 7-like 2 (T-cell specific, HMG-box)



[BLAST]


212762_s_at
transcription factor 7-like 2 (T-cell specific, HMG-box)



[BLAST]


212770_at
pleckstrin homology domain-containing, family A



(phosphoinositide binding specific) member 4


212774_at
zinc finger protein 238


212825_at
PAX transcription activation domain interacting protein 1



like


212887_at
Sec23 homolog A (S. cerevisiae)


212890_at
integrin, beta 1 (fibronectin receptor, beta polypeptide,



antigen CD29 includes MDF2, MSK12)


212900_at
SEC24 related gene family, member A (S. cerevisiae)


212919_at
FGD1 family, member 3 [BLAST]


212929_s_at
fatty-acid-Coenzyme A ligase, long-chain 6


212936_at
neurocalcin delta [BLAST]


212955_s_at
polymerase (RNA) II (DNA directed) polypeptide I (14.5 kD)


212973_at
Consensus includes gb: AI692341 /FEA = EST



/DB_XREF = gi: 4969681 /DB_XREF = est: wd85g04.x1 /CLONE = IMAGE: 2338422



/UG = Hs.79886 ribose 5-phosphate isomerase A (ribose 5-phosphate



epimerase)


212987_at
F-box only protein 9


212993_at
G protein-coupled receptor kinase 7


213026_at
APG12 autophagy 12-like (S. cerevisiae)


213029_at
son of sevenless homolog 1 (Drosophila) [BLAST]


213032_at
son of sevenless homolog 1 (Drosophila) [BLAST]


213041_s_at
ATP synthase, H+ transporting, mitochondrial F1 complex,



delta subunit


213050_at
activity-regulated cytoskeleton-associated protein


213051_at
low voltage-activated T-type calcium channel alpha-1



subunit (CACNA1I)


213057_at
ATP synthase mitochondrial F1 complex assembly factor 2



[BLAST]


213089_at
Consensus includes gb: AU158490 /FEA = EST



/DB_XREF = gi: 11020011 /DB_XREF = est: AU158490 /CLONE = PLACE3000042



/UG = Hs.303632 Human DNA sequence from clone RP11-110H4 on chromosome



5 Contains a pseudogene . . .


213145_at
nucleoporin 133 kD [BLAST]


213154_s_at
chromosome 17 open reading frame 31


213182_x_at
Consensus includes gb: R78668 /FEA = EST /DB_XREF = gi: 854949



/DB_XREF = est: yi74c04.r1 /CLONE = IMAGE: 144966 /UG = Hs.106070 cyclin-



dependent kinase inhibitor 1C (p57, Kip2)


213212_x_at
F-box only protein 21


213243_at
F-box and WD-40 domain protein 1B


213263_s_at
mitogen-activated protein kinase kinase kinase 12


213294_at
aldo-keto reductase family 1, member C1 (dihydrodiol



dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)


213302_at
phosphoribosylformylglycinamidine synthase (FGAR



amidotransferase)


213304_at
mitochondrial ribosomal protein S27


213313_at
nucleoporin 62 kD


213318_s_at
HLA-B associated transcript 3


213360_s_at
chromosome 21 open reading frame 108


213378_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-



like helicase homolog, S. cerevisiae)


213390_at
chromosome 19 open reading frame 7


213398_s_at
mitochondrial ribosomal protein S22


213400_s_at
transducin (beta)-like 1X-linked [BLAST]


213410_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 1


213428_s_at
collagen, type VI, alpha 1


213460_x_at
chromosome 21 open reading frame 108


213505_s_at
C-type (calcium dependent, carbohydrate-recognition



domain) lectin, superfamily member 1 (cartilage-derived)


213518_at
RNA binding motif protein 15


213581_at
chromosome 21 open reading frame 67


213645_at
Consensus includes gb: AF305057 /DEF = Homo sapiens RTS



(RTS) gene, complete cds, alternatively spliced /FEA = mRNA_1



/DB_XREF = gi: 11094017 /UG = Hs.180433 rTS beta protein


213668_s_at
Consensus includes gb: AI989477 /FEA = EST



/DB_XREF = gi: 5836358 /DB_XREF = est: ws25bl1.x1 /CLONE = IMAGE: 2498205



/UG = Hs.83484 SRY (sex determining region Y)-box 4


213670_x_at
chromosome 21 open reading frame 108


213682_at
Consensus includes gb: AL036344 /FEA = EST



/DB_XREF = gi: 5927743 /DB_XREF = est: DKFZp564A053_r1 /CLONE = DKFZp564A053



/UG = Hs.169329 DKFZP564A043 protein


213704_at
Rab geranylgeranyltransferase, beta subunit


213720_s_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily a, member 4 [BLAST]


213746_s_at
filamin A, alpha (actin binding protein 280) [BLAST]


213773_x_at
LUC7-like (S. cerevisiae)


213838_at
RAN binding protein 9


213842_x_at
Williams Beuren syndrome chromosome region 22


213872_at
Consensus includes gb: BE465032 /FEA = EST



/DB_XREF = gi: 9510807 /DB_XREF = est: hv76g09.x1 /CLONE = IMAGE: 3179392



/UG = Hs.173685 hypothetical protein FLJ12619


213887_s_at
polymerase (RNA) II (DNA directed) polypeptide E (25 kD)



[BLAST]


213892_s_at
adenine phosphoribosyltransferase


213923_at
RAP2B, member of RAS oncogene family


213947_s_at
Rho-related BTB domain containing 2 [BLAST]


213977_s_at
neuronal guanine nucleotide exchange factor


213998_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72 kD)


214020_x_at
integrin, beta 5


214035_x_at
nuclear pore complex interacting protein


214093_s_at
RNA polymerase I associated factor, 53 kD


214097_at
ribosomal protein S21


214100_x_at
LUC7-like (S. cerevisiae)


214113_s_at
RNA binding motif protein 8A


214149_s_at
Consensus includes gb: AI252582 /FEA = EST



/DB_XREF = gi: 3849111 /DB_XREF = est: qv25b02.x1 /CLONE = IMAGE: 1982571



/UG = Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton



pump) 9 kD


214211_at
ferritin, heavy polypeptide 1


214239_x_at
zinc finger protein 144 (Mel-18)


214246_x_at
cholinergic receptor, nicotinic, epsilon polypeptide


214259_s_at
aldo-keto reductase family 7, member A2 (aflatoxin



aldehyde reductase)


214356_s_at
pumilio homolog 2 (Drosophila)


214383_x_at
testis intracellular mediator protein


214484_s_at
protease, serine, 16 (thymus)


214500_at
H2A histone family, member Y


214531_s_at
sorting nexin 1


214581_x_at
tumor necrosis factor receptor superfamily, member 21


214657_s_at
Consensus includes gb: AU134977 /FEA = EST



/DB_XREF = gi: 10995516 /DB_XREF = est: AU134977 /CLONE = PLACE1000926



/UG = Hs.322149 Human clone 137308 mRNA, partial cds


214679_x_at
Consensus includes gb: AL110227.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp434J194 (from clone DKFZp434J194). /FEA = mRNA



/DB_XREF = gi: 5817165 /UG = Hs.323067 Homo sapiens mRNA; cDNA



DKFZp434J194 (from clone . . .


214753_at
Consensus includes gb: AW084068 /FEA = EST



/DB_XREF = gi: 6039220 /DB_XREF = est: xc26c06.x1 /CLONE = IMAGE: 2585386



/UG = Hs.110630 Human BRCA2 region, mRNA sequence CG006


214870_x_at
Consensus includes gb: AC002045 /DEF = Human Chromosome 16



BAC clone CIT987SK-A-589H1 /FEA = mRNA_2 /DB_XREF = gi: 2951945



/UG = Hs.251928 nuclear pore complex interacting protein


214911_s_at
Consensus includes gb: S78771.1 /DEF = NAT = CpG island-



associated gene human, mRNA, 1741 nt. /FEA = mRNA /DB_XREF = gi: 244232



/UG = Hs.75243 bromodomain-containing 2


214919_s_at
baculoviral IAP repeat-containing 6 (apollon)


215001_s_at
glutamate-ammonia ligase (glutamine synthase)


215089_s_at
Protein tyrosine phosphatase, receptor type, epsilon



polypeptide


215210_s_at
dihydrolipoamide S-succinyltransferase (E2 component of



2-oxo-glutarate complex)


215235_at
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


215245_x_at
fragile X mental retardation 1 [BLAST]


215464_s_at
phosphoinositide-3-kinase, regulatory subunit 4, p150


215482_s_at
PRP31 pre-mRNA processing factor 31 homolog (yeast)


215498_s_at
mitogen-activated protein kinase kinase 3


215690_x_at
GPAA1P anchor attachment protein 1 homolog (yeast)


215696_s_at
aryl-hydrocarbon receptor nuclear translocator 2


215731_s_at
M-phase phosphoprotein 9


215735_s_at
tuberous sclerosis 2


215807_s_at
plexin B1


215823_x_at
Consensus includes gb: U64661 /DEF = Human poly(A)-binding



protein processed pseudogene3 /FEA = mRNA /DB_XREF = gi: 1519214



/UG = Hs.283767 poly(A)-binding protein, cytoplasmic, pseudogene 3


215884_s_at
ubiquilin 2


216033_a_at
chromosome 20 open reading frame 100


216237_s_at
MCM5 minichromosome maintenance deficient 5, cell



division cycle 46 (S. cerevisiae) [BLAST]


216264_s_at
laminin, beta 2 (laminin S)


216384_x_at
Consensus includes gb: AF257099 /DEF = Homo sapiens



prothymosin alpha (PTMA) gene, complete cds /FEA = CDS



/DB_XREF = gi: 8037944 /UG = Hs.283947 Homo sapiens prothymosin alpha



(PTMA) gene, complete cds


216457_s_at
pecanex-like 3 (Drosophila)


216565_x_at
Consensus includes gb: AL121994 /DEF = Human DNA sequence



from clone RP4-781L3 on chromosome 1p34.3-36.11 Contains a pseudogene



similar to IFITM3 (interferon inducedntransmembrane protein 3 (1-



8U), . . .


216620_s_at
Rho guanine nucleotide exchange factor (GEF) 10


216894_x_at
Consensus includes gb: D64137 /DEF = Human KIP2 gene for



Cdk-inhibitor p57KIP2, complete cds (exon1-4) /FEA = mRNA_4



/DB_XREF = gi: 992945 /UG = Hs.106070 cyclin-dependent kinase inhibitor 1C



(p57, Kip2)


216913_s_at
Rho-related BTB domain containing 2 [BLAST]


216952_s_at
lamin B2


217028_at
chemokine (C-X-C motif), receptor 4 (fusin) [BLAST]


217168_s_at
homocysteine-inducible, endoplasmic reticulum stress-



inducible, ubiquitin-like domain member 1


217188_s_at
chromosome 14 open reading frame 1


217221_x_at
RNA binding motif protein 10


217301_x_at
retinoblastoma binding protein 4


217419_x_at
Consensus includes gb: AK021586.1 /DEF = Homo sapiens cDNA



FLJ11524 fis, clone HEMBA1002547, highly similar to Homo sapiens



agrin precursor mRNA. /FEA = mRNA /DB_XREF = gi: 10432794 /UG = Hs_273330



Homo s . . .


217716_s_at
sorting nexin 11 [BLAST]


217717_s_at
mitochondrial ribosomal protein L42


217718_s_at
mitochondrial ribosomal protein L42


217749_at
ring finger protein 12


217751_at
spastic paraplegia 3A (autosomal dominant)


217755_at
hematological and neurological expressed 1


217759_at
sperm associated antigen 10


217767_at
complement component 3


217770_at
tripartite motif-containing 33


217779_s_at
zinc finger, DHHC domain containing 7


217794_at
TAF7-like RNA polymerase II, TATA box binding protein



(TBP)-associated factor, 50 kD


217807_s_at
glioma tumor suppressor candidate region gene 2


217809_at
G protein-coupled receptor kinase-interactor 1


217836_s_at
chromosome 20 open reading frame 44


217853_at
ATP synthase mitochondrial F1 complex assembly factor 1



[BLAST]


217906_at
cyclin D-type binding-protein 1


217911_s_at
BCL2-associated athanogene 3 [BLAST]


217914_at
nucleoporin 54 kD


217918_at
ORM1-like 2 (S. cerevisiae)


217957_at
ORM1-like 2 (S. cerevisiae)


217964_at
elongation of very long chain fatty acids (FEN1/Elo2,



SUR4/Elo3, yeast)-like 2


217969_at
chromosome 11 open reading frame2


217970_s_at
solute carrier family 12, (potassium-chloride



transporter) member 5


217973_at
hydroxyacid oxidase 2 (long chain)


217983_s_at
RTC domain containing 1


217984_at
RTC domain containing 1


218001_at
mitochondrial ribosomal protein S2 [BLAST]


218010_x_at
chromosome 20 open reading frame 149


218019_s_at
FK506 binding protein 10 (65 kDa)


218035_s_at
chromosome 20 open reading frame 16


218059_at
ribosomal protein L26-like 1


218076_s_at
solute carrier family 38, member 4


218083_at
prostaglandin E synthase 2


218090_s_at
gb: NM_018117.8 /DEF = Homo sapiens WD40 repeat domain 11



protein (WDR11), mRNA. /FEA = mRNA /GEN = WDR11 /PROD = WD40 repeat domain



11 protein /DB_XREF = gi: 13324687 /UG = Hs.16677 WD repeat domain 15



/FL = gb . . .


218096_at
chromosome 20 open reading frame 46


218112_at
mitochondrial ribosomal protein S34


218123_at
chromosome 21 open reading frame 59


218135_at
toll-like receptor 7


218145_at
chromosome 20 open reading frame 97


218149_s_at
B-cell translocation gene 4


218180_s_at
RNA binding motif protein 15


218205_s_at
eukaryotic translation initiation factor 2 alpha kinase 4


218220_at
chromosome 12 open reading frame 10


218224_at
paraneoplastic antigen MA1 [BLAST]


218228_s_at
tankyrase, TRF1-interacting ankyrin-related ADP-ribose



polymerase 2


218229_s_at
myosin, heavy polypeptide 7B, cardiac muscle, beta


218241_at
golgi autoantigen, golgin subfamily a, 5


218244_at
FK506 binding protein 14 (22 kDa)


218263_s_at
ras homolog gene family, member U


218294_s_at
PRP31 pre-mRNA processing factor 31 homolog (yeast)


218315_s_at
chromosome 20 open reading frame 34


218317_x_at
ganglioside-induced differentiation-associated protein 1-



like 1


218323_at
chromosome 15 open reading frame 12


218328_at
mitochondrial ribosomal protein S2


218366_x_at
WD repeat domain 13


218379_at
RNA binding motif protein 7


218388_at
6-phosphogluconolactonase


218391_at
dual specificity phosphatase 12


218415_at
vacuolar protein sorting 33B (yeast)


218422_s_at
3-oxoacid CoA transferase 2


218437_s_at
leucine zipper transcription factor-like 1


218443_s_at
DAZ associated protein 1


218448_at
chromosome 20 open reading frame 11


218450_at
heme binding protein 1


218494_s_at
SLC2A4 regulator


218496_at
ribonuclease H1 pseudogene 1


218529_at
toll-like receptor 7


218592_s_at
cat eye syndrome chromosome region, candidate 5 [BLAST]


218652_s_at
protein phosphatase 1, regulatory (inhibitor) subunit 14D


218659_at
chromosome 20 open reading frame 36


218697_at
G-2 and S-phase expressed 1


218740_s_at
CDK5 regulatory subunit associated protein 3


218744_s_at
protein kinase C and casein kinase substrate in neurons 3


218755_at
RAB6 interacting, kinesin-like (rabkinesin6)


218756_s_at
matrix metalloproteinase 28


218767_at
chromosome 12 open reading frame 5


218773_s_at
kinesin-associated protein 3


218796_at
chromosome 20 open reading frame 42


218821_at
aminopeptidase-like 1


218839_at
hairy/enhancer-of-split related with YRPW motif 1


218848_at
MEF2-interacting transcription repressor


218856_at
mitochondrial ribosomal protein L35


218860_at
hypothetical protein, clone MTA.D02.090


218865_at
ATP synthase mitochondrial F1 complex assembly factor 1


218875_s_at
F-box only protein 5 [BLAST]


218896_s_at
chromosome Y open reading frame 14


218908_at
alveolar soft part sarcoma chromosome region, candidate 1


218921_at
testicular cell adhesion molecule 1


218983_at
immediate early response 5


218986_s_at
aldehyde reductase (aldose reductase) like 6


219007_at
hypothetical protein FLJ13287


219041_s_at
pre-B lymphocyte gene 3


219053_s_at
epsin 3


219066_at
mitochondrial ribosomal protein S35


219117_s_at
FK506 binding protein 11 (19 kDa)


219151_s_at
general transcription factor IIE, polypeptide 1 (alpha



subunit, 56 kD)


219165_at
arachidonate lipoxygenase 3


219166_at
mitochondrial ribosomal protein S18A


219188_s_at
chromosome 20 open reading frame 40


219192_at
vacuolar protein sorting 11 (yeast)


219203_at
chromosome 20 open reading frame 45


219357_at
mitochondrial ribosomal protein S28


219491_at
ganglioside-induced differentiation-associated protein 1-



like 1


219534_x_at
cyclin-dependent kinase inhibitor 1C (p57, Kip2)


219549_s_at
reticulon 3


219571_s_at
G protein-coupled receptor, family C, group 1, member B


219763_at
zinc finger protein 317


219764_at
frizzled homolog 10 (Drosophila)


219816_s_at
zinc finger, DHHC domain containing 4


219880_at
conserved intergenic sequence 2


219911_s_at
solute carrier family 21 (organic anion transporter),



member 12


219914_at
endothelin converting enzyme-like 1


220079_s_at
pecanex-like 3 (Drosophila)


220099_s_at
gb: NM_016007.1 /DEF = Homo sapiens CGI-59 protein



(LOC51625), mRNA. /FEA = mRNA /GEN = LOC51625 /PROD = CGI-59 protein



/DB_XREF = gi: 7706297 /UG = Hs.279867 CGI-59 protein /FL = gb: AF151817.1



gb: NM_016007.1


220212_s_at
neuromedin U


220597_s_at
bridging integrator 3


220690_s_at
EGF-like-domain, multiple 6


220748_s_at
serine (or cysteine) proteinase inhibitor, clade A



(alpha-1 antiproteinase, antitrypsin), member 10


220925_at
transgene insertion A2, Pierre Coulombe


220954_s_at
solute carrier family 2, (facilitated glucose



transporter) member 8


221050_s_at
GTP binding protein 2


221203_s_at
hypoxia-inducible factor 1, alpha subunit inhibitor


221264_s_at
Alpha1,2-fucosyltransferase a [BLAST]


221269_s_at
SH3 domain binding glutamic acid-rich protein like 3



[BLAST]


221500_s_at
syntaxin 16


221501_x_at
nuclear pore complex interacting protein


221509_at
density-regulated protein


221562_s_at
sirtuin silent mating type information regulation 2



homolog 3 (S. cerevisiae)


221619_s_at
ATP-binding cassette, sub-family D (ALD), member 1,



pseudogene 1


221647_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 35


221689_s_at
Down syndrome critical region gene 5


221699_s_at
ganglioside-induced differentiation-associated protein 1-



like 1 [BLAST]


221712_s_at
protocadherin beta 17 pseudogene [BLAST]


221725_at
WAS protein family, member 2


221741_s_at
chromosome 20 open reading frame 21


221746_at
ubiquitin-like 4


221759_at
ribosomal protein S4-like 2


221766_s_at
Consensus includes gb: AW246673 /FEA = EST



/DB_XREF = gi: 6589666 /DB_XREF = est: 2821951.3prime /CLONE = IMAGE: 2821951



/UG = Hs.10784 hypothetical protein FLJ20037


221786_at
Consensus includes gb: BF197222 /FEA = EST



/DB_XREF = gi: 11085906 /DB_XREF = est: 7m88b07.x1 /CLONE = IMAGE: 3561949



/UG = Hs.12342 Homo sapiens clone 24538 mRNA sequence


221789_x_at
solute carrier family 25 (mitochondrial oxodicarboxylate



carrier), member 21


221816_s_at
ankyrin repeat and SOCS box-containing 3 [BLAST]


221827_at
chromosome 20 open reading frame 18


221919_at
heterogeneous nuclear ribonucleoprotein A1


221931_s_at
chromosome 20 open reading frame 150


221932_s_at
insulin-like growth factor 2, antisense


221989_at
ribosomal protein L10


222010_at
acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl



Coenzyme A thiolase)


222011_s_at
acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl



Coenzyme A thiolase)


222037_at
MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)


222040_at
heterogeneous nuclear ribonucleoprotein A1


222122_s_at
retinoic acid induced 17 [BLAST]


222131_x_at
solute carrier family 25 (mitochondrial oxodicarboxylate



carrier), member 21


222154_s_at
golgi reassembly stacking protein 2, 55 kDa


222155_s_at
chromosome 1 open reading frame 28


222206_s_at
p21(CDKN1A)-activated kinase 6


222369_at
ribosomal protein L36a
















TABLE 2







genes up-regulated at day 5








Gene Name
Gene Description





200000_s_at
PRP8 pre-mRNA processing factor 8 homolog (yeast)


200023_s_at
eukaryotic translation initiation factor 3, subunit 5



(epsilon, 47 kD)


200044_at
splicing factor, arginine/serine-rich 9


200047_s_at
YY1 transcription factor


200055_at
TAF10 RNA polymerase II, TATA box binding protein (TBP)-



associated factor, 30 kD


200069_at
squamous cell carcinoma antigen recognised by T cells 3


200071_at
sin3-associated polypeptide, 18 kD


200083_at
ubiquitin specific protease 22


31874_at
growth arrest-specific 2 like 1


32137_at
jagged 2


33132_at
cleavage and polyadenylation specific factor 1, 160 kD



subunit


33322_i_at
stratifin


34764_at
activity-dependent neuroprotector


36553_at
acetylserotonin O-methyltransferase-like


37462_i_at
splicing factor 3a, subunit 2, 66 kD


37652_at
ribosomal protein L13a


38157_at
dom-3 homolog Z (C. elegans)


39248_at
aquaporin 3


39729_at
peroxiredoxin 2 [BLAST]


39835_at
SET binding factor 1


40465_at
fatty acid desaturase 2


40472_at
peroxisomal farnesylated protein


41047_at
chromosome 9 open reading frame 16


41858_at
RAB30, member RAS oncogene family [BLAST]


44111_at
vacuolar protein sorting 33B (yeast)


44654_at
ribosomal protein S4-like 2


44696_at
protocadherin beta 17 pseudogene


46665_at
sema domain, immunoglobulin domain (Ig), transmembrane



domain (TM) and short cytoplasmic domain, (semaphorin) 4C


47069_at
Rho GTPase activating protein 8


47083_at
prion protein interacting protein


50314_i_at
chromosome 20 open reading frame 27


52164_at
chromosome 11 open reading frame 24


53071_s_at
hypothetical protein FLJ22222


59625_at
nucleolar protein 3 (apoptosis repressor with CARD



domain)


55872_at
solute carrier family 12, (potassium-chloride



transporter) member 5


60474_at
chromosome 20 open reading frame 42


64474_g_at
RNA binding motif protein 15


65884_at
mannosidase, alpha, class 1B, member 1


91703_at
integrin, beta 1 (fibronectin receptor, beta polypeptide,



antigen CD29 includes MDF2, MSK12)


200593_s_at
gb: BC003621.1 /DEF = Homo sapiens, heterogeneous nuclear



ribonucleoprotein U (scaffold attachment factor A), clone MGC: 1992,



mRNA, complete cds. /FEA = mRNA /PROD = heterogeneous nuclear



ribonucleopro . . .


200618_at
LIM and SH3 protein 1


200619_at
splicing factor 3b, subunit 2, 145 kD


200637_s_at
protein tyrosine phosphatase, receptor type, F


200655_s_at
calmodulin 1 (phosphorylase kinase, delta)


200675_at
CD81 antigen (target of antiproliferative antibody 1)


200702_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 24 [BLAST]


200707_at
protein kinase C substrate 80K—H


200710_at
acyl-Coenzyme A dehydrogenase, very long chain


200743_s_at
ceroid-lipofuscinosis, neuronal 2, late infantile



(Jansky-Bielschowsky disease)


200747_s_at
nuclear mitotic apparatus protein 1


200766_at
cathepsin D (lysosomal aspartyl protease)


200810_s_at
cold inducible RNA binding protein


200816_s_at
platelet-activating factor acetylhydrolase, isoform Ib,



alpha subunit (45 kD)


200827_at
procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine



hydroxylase, Ehlers-Danlos syndrome type VI)


200864_s_at
RAB11A, member RAS oncogene family


200867_at
zinc finger protein 313


200875_s_at
nucleolar protein 5A (56 kD with KKE/D repeat)


200884_at
creatine kinase, brain


200891_s_at
signal sequence receptor, alpha (translocon-associated



protein alpha)


200903_s_at
S-adenosylhomocysteine hydrolase


200914_x_at
kinectin 1 (kinesin receptor)


200918_s_at
signal recognition particle receptor (‘docking protein’)


200950_at
actin related protein 2/3 complex, subunit 1A (41 kD)


200959_at
fusion, derived from t(12; 16) malignant liposarcoma


200965_s_at
actin binding LIM protein


200967_at
peptidylprolyl isomerase B (cyclophilin B)


200968_s_at
peptidylprolyl isomerase B (cyclophilin B)


200980_s_at
pyruvate dehydrogenase (lipoamide) alpha 1


200990_at
gb: NM_005762.1 /DEF = Homo sapiens KRAB-associated protein



1 (TIF1B), mRNA. /FEA = mRNA /GEN = TIF1B /PROD = KRAB-associated protein 1



/DB_XREF = gi: 5032178 /UG = Hs.228059 KRAB-associated protein 1 /FL = gb: B



. . .


201003_x_at
gb: NM_003349.2 /DEF = Homo sapiens ubiqtiitin-conjugating



enzyme E2 variant 1 (UBE2V1), transcript variant 2, mRNA. /FEA = mRNA



/GEN = UBE2V1 /PROD = ubiquitin-conjugating enzyme E2 variant 1, isoform b



/ . . .


201008_s_at
thioredoxin interacting protein


201011_at
ribophorin I


201015_s_at
junction plakoglobin


201024_x_at
Consensus includes gb: BG261322 /FEA = EST



/DB_XREF = gi: 12771138 /DB_XREF = est: 602373079F1 /CLONE = IMAGE: 4484563



/UG = Hs.158688 KIAA0741 gene product /FL = gb: AB018284.1 gb: AF078035.1



gb: NM_015904.1


201034_at
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain


201037_at
phosphofructokinase, platelet


201052_s_at
proteasome (prosome, macropain) inhibitor subunit 1



(PI31)


201054_at
heterogeneous nuclear ribonucleoprotein A0 [BLAST]


201064_s_at
poly(A) binding protein, cytoplasmic 4 (inducible form)


201065_s_at
general transcription factor II, i [BLAST]


201074_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily c, member 1


201079_at
synaptogyrin 2


201082_s_at
dynactin 1 (p150, glued homolog, Drosophila)


201102_s_at
phosphofructokinase, liver


201113_at
Tu translation elongation factor, mitochondrial


201128_s_at
ATP citrate lyase


201129_at
gb: NM_006276.2 /DEF = Homo sapiens splicing factor,



arginineserine-rich 7 (35 kD) (SFRS7), mRNA. /FEA = mRNA /GEN = SFRS7



/PROD = splicing factor, arginineserine-rich 7 (35 kD)



/DB_XREF = gi: 6857827 /UG = Hs. . . .


201160_s_at
cold shock domain protein A


201161_s_at
cold shock domain protein A


201176_s_at
archain 1


201188_s_at
inositol 1,4,5-triphosphate receptor, type 3


201189_s_at
inositol 1,4,5-triphosphate receptor, type 3


201198_s_at
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1


201209_at
histone-deacetylase 1


201244_s_at
v-raf-1 murine leukemia viral oncogene homolog 1


201247_at
sterol regulatory element binding transcription factor 2


201255_x_at
HLA-B associated transcript 3


201264_at
coatomer protein complex, subunit epsilon


201271_s_at
RNA binding protein (autoantigenic, hnRNP-associated with



lethal yellow)


201296_s_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 1


201310_s_at
Kruppel-like factor 4 (gut)


201313_at
gb: NM_001975.1 /DEF = Homo sapiens enolase 2, (gamma,



neuronal) (ENO2), mRNA. /FEA = mRNA /GEN = ENO2 /PROD = enolase 2, (gamma,



neuronal) /DB_XREF = gi: 5803010 /UG = Hs.146580 enolase 2, (gamma,



neuronal) / . . .


201315_x_at
interferon induced transmembrane protein 2 (1-8D)


201331_s_at
signal transducer and activator of transcription-6,



interleukin-4 induced


201356_at
splicing factor 3a, subunit 1, 120 kD


201360_at
cystatin C (amyloid angiopathy and cerebral hemorrhage)


201362_at
polymerase (RNA) III (DNA directed) polypeptide F (39 kD)


201363_s_at
polymerase (RNA) III (DNA directed) polypeptide F (39 kD)


201373_at
plectin 1, intermediate filament binding protein, 500 kD


201379_s_at
tumor protein D52-like 2


201413_at
hydroxysteroid (17-beta) dehydrogenase 4


201440_at
fatty acid desaturase 2


201448_at
TIA1 cytotoxic granule-associated RNA binding protein


201454_s_at
Consensus includes gb: AW055008 /FEA = EST



/DB_XREF = gi: 5920711 /DB_XREF = est: wy98c09.x1 /CLONE = IMAGE: 2556592



/UG = Hs.293007 aminopeptidase puromycin sensitive /FL = gb: NM_006310.1


201459_at
RuvB-like 2 (E. coli)


201482_at
quiescin Q6


201489_at
peptidylprolyl isomerase F (cyclophilin F)


201498_at
ubiquitin specific protease 7 (herpes virus-associated)


201526_at
ADP-ribosylation factor 5


201545_s_at
poly(A) binding protein, nuclear 1


201555_at
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)


201564_s_at
singed-like (fascin homolog, sea urchin) (Drosophila)


201578_at
podocalyxin-like


201585_s_at
splicing factor proline/glutamine rich (polypyrimidine



tract binding protein associated)


201586_s_at
splicing factor proline/glutamine rich (polypyrimidine



tract binding protein associated)


201598_s_at
inositol polyphosphate phosphatase-like 1


201601_x_at
interferon induced transmembrane protein 1 (9-27)


201612_at
aldehyde dehydrogenase 9 family, member A1


201620_at
membrane-bound transcription factor protease, site 1


201623_s_at
aspartyl-tRNA synthetase


201624_at
aspartyl-tRNA synthetase


201639_s_at
cleavage and polyadenylation specific factor 1, 160 kD



subunit


201643_x_at
chromosome 5 open reading frame 7


201645_at
tenascin C (hexabrachion)


201650_at
keratin 19


201675_at
A kinase (PRKA) anchor protein 1


201679_at
tripartite motif-containing 33


201689_s_at
tumor protein D52


201690_s_at
tumor protein D52


201697_s_at
DNA (cytosine-5-)-methyltransferase 1


201704_at
ectonucleoside triphosphate diphosphohydrolase 6



(putative function)


201714_at
tubulin, gamma 1


201719_s_at
erythrocyte membrane protein band 4.1-like 2


201726_at
ELAV (embryonic lethal, abnormal vision, Drosophila)-like



1 (Hu antigen R)


201746_at
tumor protein p53 (Li-Fraumeni syndrome)


201747_s_at
scaffold attachment factor B


201790_s_at
7-dehydrocholesterol reductase


201795_at
lamin B receptor


201818_at
brain and acute leukemia, cytoplasmic


201828_x_at
CAAX box 1


201833_at
histone deacetylase 2


201841_s_at
heat shock 27 kD protein 1


201853_s_at
cell division cycle 25B


201885_s_at
diaphorase (NADH) (cytochrome b-5 reductase)


201889_at
family with sequence similarity 3, member C


201928_at
plakophilin 4


201937_s_at
aspartyl aminopeptidase


201970_s_at
nuclear autoantigenic sperm protein (histone-binding)


202039_at
TGFB1-induced anti-apoptotic factor 1


202043_s_at
spermine synthase


202060_at
Rho guanine nucleotide exchange factor (GEF) 10


202066_at
protein tyrosine phosphatase, receptor type, f



polypeptide (PTPRF), interacting protein (liprin), alpha 1


202097_at
nucleoporin 153 kD


202104_s_at
spastic paraplegia 7, paraplegin (pure and complicated



autosomal recessive)


202115_s_at
ATP-binding cassette, sub-family A (ABC1), member 12


202119_s_at
copine III


202127_at
myotubularin related protein 2


202130_at
sudD suppressor of bimD6 homolog (A. nidulans)


202133_at
centaurin, beta 2


202136_at
S-adenosylhomocysteine hydrolase-like 1


202139_at
aldo-keto reductase family 7, member A2 (aflatoxin



aldehyde reductase)


202151_s_at
CD2 antigen (cytoplasmic tail) binding protein 2


202159_at
phenylalanine-tRNA synthetase-like


202161_at
protein kinase C-like 1


202171_at
zinc finger protein 161


202180_s_at
major vault protein


202182_at
GCN5 general control of amino-acid synthesis 5-like 2



(yeast)


202189_x_at
polypyrimidine tract binding protein 1 [BLAST]


202219_at
solute carrier family 6 (neurotransmitter transporter,



creatine), member 8


202220_at
calsyntenin 1


202228_s_at
dynein, axonemal, intermediate polypeptide 1


202230_s_at
calcium homeostasis endoplasmic reticulum protein


202240_at
polo-like kinase (Drosophila)


202241_at
growth differentiation factor 11


202251_at
PRP4 pre-mRNA processing factor 4 homolog (yeast)


202275_at
glucose-6-phosphate dehydrogenase


202289_s_at
transforming, acidic coiled-coil containing protein 2


202308_at
sterol regulatory element binding transcription factor 1


202320_at
general transcription factor IIIC, polypeptide 1 (alpha



subunit, 220 kD)


202344_at
heat shock transcription factor 1


202357_s_at
B-factor, properdin [BLAST]


202384_s_at
Treacher Collins-Franceschetti syndrome 1


202409_at
insulin-like growth factor 2 (somatomedin A)


202411_at
interferon, alpha-inducible protein 27


202424_at
mitogen-activated protein kinase kinase 2


202430_s_at
phospholipid scramblase 1


202446_s_at
phospholipid scramblase 1


202464_s_at
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3


202478_at
immunoglobulin kappa joining 1


202510_s_at
tumor necrosis factor, alpha-induced protein 2


202534_x_at
dihydrofolate reductase


202536_at
EGF-like-domain, multiple 6


202540_s_at
3-hydroxy-3-methylglutaryl-Coenzyme A reductase


202569_s_at
MAP/microtubule affinity-regulating kinase 3


202589_at
thymidylate synthetase


202605_at
glucuronidase, beta


202686_s_at
AXL receptor tyrosine kinase


202715_at
carbamoyl-phosphate synthetase 2, aspartate



transcarbamylase, and dihydroorotase


202718_at
insulin-like growth factor binding protein 2 (36 kD)


202757_at
rotatin


202804_at
ATP-binding cassette, sub-family C (CFTR/MRP), member 1


202809_s_at
down-regulated in colon cancer 1


202812_at
glucosidase, alpha; acid (Pompe disease, glycogen storage



disease type II)


202836_s_at
mannosidase, alpha, class 1A, member 2


202853_s_at
RYK receptor-like tyrosine kinase


202870_s_at
CDC20 cell division cycle 20 homolog (S. cerevisiae)


202890_at
Consensus includes gb: AW242297 /FEA = EST



/DB_XREF = gi: 6576051 /DB_XREF = est: xm96b11.x1 /CLONE = IMAGE: 2692029



/UG = Hs.146388 microtubule-associated protein 7 /FL = gb: NM_003980.1


202917_s_at
S100 calcium binding protein A8 (calgranulin A)


202929_s_at
D-dopachrome tautomerase


202934_at
hexokinase 2 [BLAST]


202936_s_at
SRY (sex determining region Y)-box 9 (campomelic



dysplasia, autosomal sex-reversal)


202951_at
serine/threonine kinase 38


202962_at
kinesin family member 13B


202979_s_at
ras homolog gene family, member U


202998_s_at
lysyl oxidase-like 2


203021_at
secretory leukocyte protease inhibitor



(antileukoproteinase) [BLAST]


203062_s_at
heparan sulfate 2-O-sulfotransferase 1


203065_s_at
caveolin 1, caveolae protein, 22 kD [BLAST]


203067_at
cysteine and glycine-rich protein 3 (cardiac LIM protein)


203098_at
chromodomain protein, Y chromosome-like


203102_s_at
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-



acetylglucosaminyltransferase


203103_s_at
HIV TAT specific factor 1


203108_at
retinoic acid induced 3


203124_s_at
solute carrier family 11 (proton-coupled divalent metal



ion transporters), member 2


203126_at
inositol(myo)-1(or 4)-monophosphatase 2


203137_at
M-phase phosphoprotein 1


203153_at
interferon-induced protein with tetratricopeptide repeats 1


203155_at
SET domain, bifurcated 1


203184_at
fibrillin 2 (congenital contractural arachnodactyly)


203189_s_at
NADH dehydrogenase (ubiquinone) Fe—S protein 8 (23 kD)



(NADH-coenzyme Q reductase)


203198_at
cyclin-dependent kinase 9 (CDC2-related kinase) [BLAST]


203219_s_at
adenine phosphoribosyltransferase


203224_at
chromosome 20 open reading frame 38


203234_at
uridine phosphorylase


203244_at
peroxisome receptor 1


203252_at
gb: NM_005851.1 /DEF = Homo sapiens tumor suppressor deleted



in oral cancer-related 1 (DOC-1R), mRNA. /FEA = mRNA /GEN = DOC-1R



/PROD = tumor suppressor deleted in oral cancer-related1



/DB_XREF = gi: 503166 . . .


203262_s_at
DNA segment on chromosome X (unique) 9928 expressed



sequence


203276_at
lamin B1


203282_at
glucan (1,4-alpha-), branching enzyme 1 (glycogen



branching enzyme, Andersen disease, glycogen storage disease type IV)


203286_at
Rho-related BTB domain containing 3


203338_at
protein phosphatase 2, regulatory subunit B (B56)-,



epsilon isoform


203386_at
chromosome 21 open reading frame 108


203391_at
gb: NM_004470.1 /DEF = Homo sapiens FK506-binding protein 2



(13 kD) (FKBP2), mRNA. /FEA = mRNA /GEN = FKBP2 /PROD = FK506-binding



protein 2 (13 kD) /DB_XREF = gi: 4758381 /UG = Hs.227729 FK506-binding



protein 2 . . .


203417_at
microfibrillar-associated protein 2


203439_s_at
stanniocalcin 2


203477_at
collagen, type XV, alpha 1


203482_at
zinc finger protein 334


203495_at
syndecan 3 (N-syndecan)


203552_at
mitogen-activated protein kinase kinase kinase kinase 5



[BLAST]


203564_at
Fanconi anemia, complementation group G


203612_at
bystin-like [BLAST]


203683_s_at
vascular endothelial growth factor B


203701_s_at
chromosome 20 open reading frame 13


203739_at
zinc finger protein 217


203767_s_at
steroid sulfatase (microsomal), arylsulfatase C, isozyme S


203775_at
solute carrier family 25, member 13 (citrin)


203802_x_at
LUC7-like (S. cerevisiae)


203818_s_at
splicing factor 3a, subunit 3, 60 kD


203825_at
bromodomain containing 3


203828_s_at
zinc finger protein 206


203831_at
[BLAST]


203848_at
A kinase (PRKA) anchor protein 8


203867_s_at
toll interacting protein


203919_at
transcription elongation factor A (SII), 2


203955_at
GRB2-associated binding protein 2


203974_at
synapsin III


203976_s_at
chromatin assembly factor 1, subunit A (p150)


204022_at
abhydrolase domain containing 1


204030_s_at
schwannomin interacting protein 1


204058_at
malic enzyme 1, NADP(+)-dependent, cytosolic


204133_at
cyclin E2


204136_at
collagen, type VII, alpha 1 (epidermolysis bullosa,



dystrophic, dominant and recessive)


204142_at
SRY (sex determining region Y)-box 6


204143_s_at
SRY (sex determining region Y)-box 6


204178_s_at
RNA binding motif protein 14


204224_s_at
GTP cyclohydrolase 1 (dopa-responsive dystonia)


204238_s_at
secretagogin, EF-hand calcium binding protein


204274_at
Consensus includes gb: AA812215 /FEA = EST



/DB_XREF = gi: 2881826 /DB_XREF = est: ob84g01.s1 /CLONE = IMAGE: 1338096



/UG = Hs.9222 estrogen receptor binding site associated, antigen, 9



/FL = gb: BC005249.1 gb: AF0 . . .


204275_at
small optic lobes homolog (Drosophila)


204295_at
surfeit 1


204372_s_at
KH-type splicing regulatory protein (FUSE binding protein



2)


204383_at
clathrin, heavy polypeptide-like 1


204401_at
potassium intermediate/small conductance calcium-



activated channel, subfamily N, member 4


204409_s_at
eukaryotic translation initiation factor 1A, Y chromosome


204475_at
matrix metalloproteinase 1 (interstitial collagenase)


204480_s_at
chromosome 9 open reading frame 16


204520_x_at
bromodomain containing 1


204521_at
cleavage and polyadenylation specific factor 1, 160 kD



subunit


204531_s_at
breast cancer 1, early onset


204617_s_at
aquaporin 9


204698_at
interferon stimulated gene (20 kD)


204717_s_at
solute carrier family 29 (nucleoside transporters),



member 2


204808_s_at
transmembrane protein 5


204839_at
membrane-bound transcription factor protease, site 2


204849_at
transcription factor-like 5 (basic helix-loop-helix)


204857_at
MAD1 mitotic arrest deficient-like 1 (yeast)


204858_s_at
endothelial cell growth factor 1 (platelet-derived)


204875_s_at
GDP-mannose 4,6-dehydratase


204908_s_at
B-cell CLL/lymphoma 3


204990_s_at
integrin, beta 4


205000_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y



chromosome


205053_at
primase, polypeptide 1 (49 kD)


205068_s_at
paternally expressed 10


205155_s_at
spectrin, beta, non-erythrocytic 2


205199_at
carbonic anhydrase IX


205202_at
protein-L-isoaspartate (D-aspartate) O-methyltransferase


205353_s_at
prostatic binding protein


205382_s_at
D component of complement (adipsin)


205412_at
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl



Coenzyme A thiolase)


205436_s_at
H2A histone family, member X


205449_at
cleavage and polyadenylation specific factor 1, 160 kD



subunit


205501_at
phosphodiesterase 10A


205516_x_at
neuronal guanine nucleotide exchange factor


205527_s_at
gem (nuclear organelle) associated protein 4


205534_at
BH-protocadherin (brain-heart) [BLAST]


205546_s_at
tyrosine kinase 2


205552_s_at
2′,5′-oligoadenylate synthetase 1 (40-46 kD)


205565_s_at
Friedreich ataxia


205583_s_at
NIMA (never in mitosis gene a)-related kinase 11


205658_s_at
small nuclear RNA activating complex, polypeptide 4,



190 kD


205780_at
BCL2-interacting/killer (apoptosis-inducing)


205961_s_at
gb: NM_004682.1 /DEF = Homo sapiens PC4 and SFRS1



interacting protein 2 (PSIP2), mRNA. /FEA = mRNA /GEN = PSIP2 /PROD = PC4



and SFRS1 interacting protein 2 /DB_XREF = gi: 4758869 /UG = Hs.306179 PC4



and SFRS1 . . .


206023_at
neuromedin U


206095_s_at
gb: NM_006625.2 /DEF = Homo sapiens TLS-associated serine-



arginine protein 1 (TASR1), mRNA. /FEA = mRNA /GEN = TASR1 /PROD = TLS-



associated serine-arginine protein 1 /DB_XREF = gi: 12056474



/UG = Hs.288038 TL . . .


206102_at
tripartite motif-containing 14


206200_s_at
annexin A11


206332_s_at
interferon, gamma-inducible protein 16


206499_s_at
chromosome condensation 1


206785_s_at
killer cell lectin-like receptor subfamily C, member 2


206809_s_at
heterogeneous nuclear ribonucleoprotein A3


207002_s_at
pleiomorphic adenoma gene-like 1


207076_s_at
argininosuccinate synthetase [BLAST]


207122_x_at
sulfotransferase family, cytosolic, 1A, phenol-



preferring, member 2


207140_at
alkaline phosphatase, intestinal


207165_at
hyaluronan-mediated motility receptor (RHAMM)


207196_s_at
UDP-Gal: betaGlcNAc beta 1,3-galactosyltransferase,



polypeptide 5


207414_s_at
paired basic amino acid cleaving system 4


207564_x_at
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-



acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)


207622_s_at
ATP-binding cassette, sub-family F (GCN20), member 2


207714_s_at
serine (or cysteine) proteinase inhibitor, clade H (heat



shock protein 47), member 1, (collagen binding protein 1)


207723_s_at
killer cell lectin-like receptor subfamily C, member 3


207760_s_at
nuclear receptor co-repressor 2


207761_s_at
component of oligomeric golgi complex 4


207824_s_at
MYC-associated zinc finger protein (purine-binding



transcription factor)


207831_x_at
deoxyhypusine synthase


207842_s_at
zyxin [BLAST]


207847_s_at
mucin 1, transmembrane


208072_s_at
diacylglycerol kinase, delta (130 kD)


208149_x_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-



like helicase homolog, S. cerevisiae) [BLAST]


208152_s_at
gb: NM_004728.1 /DEF = Homo sapiens DEADH (Asp-Glu-Ala-



AspHis) box polypeptide 21 (DDX21), mRNA. /FEA = mRNA /GEN = DDX21



/PROD = DEADH (Asp-Glu-Ala-AspHis) box polypeptide 21



/DB_XREF = gi: 13787208 /FL = gb . . .


208156_x_at
gb: NM_031308.1 /DEF = Homo sapiens epiplakin 1 (EPPK1),



mRNA. /FEA = mRNA /GEN = EPPK1 /PROD = epiplakin 1 /DB_XREF = gi: 13876385



/FL = gb: NM_031308.1


208159_x_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-



like helicase homolog, S. cerevisiae)


208248_x_at
amyloid beta (A4) precursor-like protein 2


208270_s_at
arginyl aminopeptidase (aminopeptidase B)


208313_s_at
splicing factor 1


208336_s_at
glycoprotein, synaptic 2


208407_s_at
catenin (cadherin-associated protein), delta 1


208436_s_at
interferon regulatory factor 7


208617_s_at
protein tyrosine phosphatase type IVA, member 2


208621_s_at
villin 2 (ezrin)


208625_s_at
eukaryotic translation initiation factor 4 gamma, 1


208636_at
actinin, alpha 1


208647_at
farnesyl-diphosphate farnesyltransferase 1


208655_at
cyclin I


208676_s_at
chromosome 20 open reading frame 54


208700_s_at
transketolase (Wernicke-Korsakoff syndrome)


208703_s_at
amyloid beta (A4) precursor-like protein 2


208713_at
protein tyrosine phosphatase, non-receptor type 21


208714_at
NADH dehydrogenase (ubiquinone) flavoprotein 1 (51 kD)


208719_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72 kD)


208729_x_at
major histocompatibility complex, class I, B


208774_at
casein kinase 1, delta


208794_s_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily a, member 4


208804_s_at
splicing factor, arginine/serine-rich 6


208809_s_at
gb: AL136632.1 /DEF = Homo sapiens mRNA; cDNA DKFZp564G182



(from clone DKFZp564G182); complete cds. /FEA = mRNA /GEN = DKFZp564G182



/PROD = hypothetical protein /DB_XREF = gi: 12052789 /UG = Hs.173685 hypothe . . .


208820_at
PTK2 protein tyrosine kinase 2


208858_s_at
WD repeat domain 7


208863_s_at
splicing factor, arginine/serine-rich 1 (splicing factor



2, alternate splicing factor)


208880_s_at
chromosome 20 open reading frame 14


208890_s_at
plexin B2


208891_at
dual specificity phosphatase 6


208892_s_at
dual specificity phosphatase 6


208906_at
ligand of numb-protein X


208912_s_at
gb: BC001362.1 /DEF = Homo sapiens, 2,3-cyclic nucleotide 3



phosphodiesterase, clone MGC: 2262, mRNA, complete cds. /FEA = mRNA



/PROD = 2,3-cyclic nucleotide 3 phosphodiesterase /DB_XREF = gi: 12655028



/UG . . .


208923_at
cytoplasmic FMR1 interacting protein 1


208928_at
P450 (cytochrome) oxidoreductase


208930_s_at
interleukin enhancer binding factor 3, 90 kD


208938_at
papillary renal cell carcinoma (translocation-associated)


208968_s_at
aldo-keto reductase family 1, member B10 (aldose



reductase)


208978_at
cysteine-rich protein 2


208984_x_at
RNA binding motif protein 10


208998_at
uncoupling protein 2 (mitochondrial, proton carrier)


209007_s_at
solute carrier family 17 (sodium-dependent inorganic



phosphate cotransporter), member 7


209029_at
COP9 constitutive photomorphogenic homolog subunit 7A



(Arabidopsis)


209053_s_at
Wolf-Hirschhorn syndrome candidate 1


209054_s_at
Wolf-Hirschhorn syndrome candidate 1


209075_s_at
bromodomain containing 4


209118_s_at
platelet-activating factor acetylhydrolase, isoform Ib,



pseudogene 1


209120_at
nuclear receptor subfamily 2, group F, member 2


209122_at
adipose differentiation-related protein


209140_x_at
major histocompatibility complex, class I, B


209153_s_at
transcription factor 3 (E2A immunoglobulin enhancer



binding factors E12/E47)


209156_s_at
collagen, type VI, alpha 2


209173_at
anterior gradient 2 homolog (Xenepus laevis)


209215_at
glycoprotein A33 (transmembrane)


209228_x_at
zinc finger protein 212


209236_at
solute carrier family 23 (nucleobase transporters),



member 1


209262_s_at
nuclear receptor subfamily 2, group F, member 6


209263_x_at
transmembrane 4 superfamily member 7


209265_s_at
thioredoxin interacting protein


209289_at
nuclear factor I/B


209290_s_at
nuclear factor I/B


209332_s_at
MAX protein


209337_at
gb: AF063020.1 /DEF = Homo sapiens lens epithelium-derived



growth factor mRNA, complete cds. /FEA = mRNA /PROD = lens epithelium-



derived growth factor /DB_XREF = gi: 3283351 /UG = Hs.82110 PC4 and SFRS1



int . . .


209341_s_at
inhibitor of kappa light polypeptide gene enhancer in B-



cells, kinase beta


209407_s_at
deformed epidermal autoregulatory factor 1 (Drosophila)


209409_at
growth factor receptor-bound protein 10


209449_at
chromosome 6 open reading frame 28


209496_at
retinoic acid receptor responder (tazarotene induced) 2


209505_at
nuclear receptor subfamily 2, group F, member 1


209581_at
HRAS-like suppressor 3


209607_x_at
sulfotransferase family, cytosolic, 1A, phenol-



preferring, member 3


209623_at
methylcrotonoyl-Coenzyme A carboxylase 2 (beta) [BLAST]


209630_s_at
G protein-coupled receptor 37 (endothelin receptor type



B-like)


209723_at
serine (or cysteine) proteinase inhibitor, clade B



(ovalbumin), member 9


209729_at
growth arrest-specific 2 like 1


209759_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 37


209784_s_at
jagged 2


209873_s_at
plakophilin 3


209899_s_at
DnaJ (Hsp40) homolog, subfamily C, member 8 [BLAST]


210010_s_at
solute carrier family 25 (mitochondrial carrier; citrate



transporter), member 1


210026_s_at
succinate dehydrogenase complex, subunit D, integral



membrane protein pseudogene 1


210028_s_at
origin recognition complex, subunit 3-like (yeast)


210069_at
carnitine palmitoyltransferase I, muscle


210095_s_at
insulin-like growth factor binding protein 3


210105_s_at
FYN oncogene related to SRC, FGR, YES


210111_s_at
G protein-coupled receptor 61


210150_s_at
laminin, alpha 5


210208_x_at
HLA-B associated transcript 3


210336_x_at
zinc finger protein 42 (myeloid-specific retinoic acid-



responsive)


210337_s_at
ATP citrate lyase


210371_s_at
retinoblastoma binding protein 4


210410_s_at
mutS homolog 5 (E. coli)


210448_s_at
purinergic receptor P2X, ligand-gated ion channel, 5


210802_s_at
serine protease inhibitor, Kazal type 4


210878_s_at
chromosome 5 open reading frame 7


210891_s_at
general transcription factor II, i


211052_s_at
tubulin-specific chaperone d [BLAST]


211060_x_at
GPAA1P anchor attachment protein 1 homolog (yeast)



[BLAST]


211065_x_at
phosphofructokinase, liver [BLAST]


211075_s_at
gb: Z25521.1 /DEF = H. sapiens integrin associated protein



mRNA, complete CDS,. /FEA = mRNA /PROD = integrin associated protein



/DB_XREF = gi: 396704 /FL = gb: Z25521.1


211270_x_at
polypyrimidine tract binding protein 1


211284_s_at
granulin


211300_s_at
tumor protein p53 (Li-Fraumeni syndrome)


211358_s_at
neuronal guanine nucleotide exchange factor


211375_s_at
interleukin enhancer binding factor 3, 90 kD


211385_x_at
sulfotransferase family, cytosolic, 1A, phenol-



preferring, member 2


211529_x_at
HLA-G histocompatibility antigen, class I, G


211564_s_at
KH-type splicing regulatory protein (FUSE binding protein



2)


211596_s_at
1(3)mbt-like (Drosophila) [BLAST]


211618_s_at
gb: M31008.1 /DEF = Human intestinal alkaline phosphatase



mRNA, complete cds. /FEA = mRNA /GEN = ALPI /DB_XREF = gi: 178443



/FL = gb: M31008.1


211678_s_at
maternally expressed 3 [BLAST]


211911_x_at
major histocompatibility complex, class I, B [BLAST]


211929_at
heterogeneous nuclear ribonucleoprotein A3


211967_at
F-box only protein 32 [BLAST]


211969_at
heat shock 90 kD protein 1, alpha


211986_at
AHNAK nucleoprotein (desmoyokin)


212015_x_at
polypyrimidine tract binding protein 1 [BLAST]


212028_at
proline dehydrogenase (oxidase) 2


212030_at
proline dehydrogenase (oxidase) 2


212032_s_at
prostate tumor over expressed gene 1 [BLAST]


212033_at
proline dehydrogenase (oxidase) 2


212037_at
pinin, desmosome associated protein


212056_at
MDN1, midasin homolog (yeast)


212062_at
ATPase, Class II, type 9A


212067_s_at
Consensus includes gb: AL573058 /FEA = EST



/DB_XREF = gi: 12931931 /DB_XREF = est: AL573058 /CLONE = CS0DI014YC05 (3



prime) /UG = Hs.1279 complement component 1, r subcomponent


212068_s_at
ATPase, Class V, type 10B


212069_s_at
ATPase, Class V, type 10B


212124_at
retinoic acid induced 17


212137_at
ATP synthase mitochondrial F1 complex assembly factor 2


212139_at
GCN1 general control of amino-acid synthesis 1-like 1



(yeast)


212143_s_at
insulin-like growth factor binding protein 3


212159_x_at
adaptor-related protein complex 2, alpha 2 subunit


212170_at
RNA binding motif protein 12


212186_at
acetyl-Coenzyme A carboxylase alpha


212203_x_at
interferon induced transmembrane protein 3 (1-8U)


212218_s_at
F-box only protein 9 [BLAST]


212231_at
F-box only protein 21


212251_at
nuclear autoantigenic sperm protein (histone-binding)



[BLAST]


212269_s_at
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)



associated protein


212285_s_at
agrin


212300_at
Consensus includes gb: AL049795 /DEF = Human DNA sequence



from clone RP4-622L5 on chromosome 1p34.2-36.11. Contains the gene



for importin alpha 7 (karyopherin), up to six novel genes and the 5



end o . . .


212307_s_at
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-



acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)


212316_at
Rho-related BTB domain containing 2


212319_at
synaptosomal-associated protein, 91 kD homolog (mouse)


212361_s_at
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2



[BLAST]


212396_s_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 2


212403_at
solute carrier family 25 (mitochondrial oxodicarboxylate



carrier), member 21 [BLAST]


212414_s_at
capicua homolog (Drosophila)


212429_s_at
general transcription factor IIIC, polypeptide 2 (beta



subunit, 110 kD)


212456_at
chromosome 21 open reading frame 80


212493_s_at
chromosome 20 open reading frame 30


212498_at
brain-specific angiogenesis inhibitor 3 [BLAST]


212499_s_at
collagen, type II, alpha I (primary osteoarthritis,



spondyloepiphyseal dysplasia, congenital) [BLAST]


212520_s_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily a, member 4


212547_at
Consensus includes gb: N34842 /FEA = EST /DB_XREF = gi: 1155984



/DB_XREF = est: yy45d11.s1 /CLONE = IMAGE: 276501 /UG = Hs.6580 Homo sapiens



cDNA: FLJ23227 fis, clone CAE00645, highly similar to AF052138 Homo



. . .


212561_at
ATPase, Class VI, type 11A


212563_at
block of proliferation 1


212566_at
ret finger protein 2


212589_at
related RAS viral (r-ras) oncogene homolog 2 -


212612_at
REST corepressor


212630_at
chromobox homolog 3 (HP1 gamma homolog, Drosophila)


212644_s_at
collagen, type II, alpha 1 (primary osteoarthritis,



spondyloepiphyseal dysplasia, congenital) [BLAST]


212647_at
related RAS viral (r-ras) oncogene homolog


212691_at
SH3-domain GRB2-like endophilin B2 [BLAST]


212693_at
MDN1, midasin homolog (yeast)


212747_at
chromosome 17 open reading frame 31 [BLAST]


212752_at
cytoplasmic linker associated protein 1


212761_at
transcription factor 7-like 2 (T-cell specific, HMG-box)



[BLAST]


212762_s_at
transcription factor 7-like 2 (T-cell specific, HMG-box)



[BLAST]


212770_at
pleckatrin homology domain-containing, family A



(phosphoinositide binding specific) member 4


212774_at
zinc finger protein 238


212825_at
PAX transcription activation domain interacting protein 1



like


212887_at
Sec23 homolog A (S. cerevisiae)


212890_at
integrin, beta 1 (fibronectin receptor, beta polypeptide,



antigen CD29 includes MDF2, MSK12)


212900_at
SEC24 related gene family, member A (S. cerevisiae)


212919_at
FGD1 family, member 3 [BLAST]


212929_s_at
fatty-acid-Coenzyme A ligase, long-chain 6


212936_at
neurocalcin delta [BLAST]


212955_s_at
polymerase (RNA) II (DNA directed) polypeptide I (14.5 kD)


212973_at
Consensus includes gb: AI692341 /FEA = EST



/DB_XREF = gi: 4969681 /DB_XREF = est: wd85g04.x1 /CLONE = IMAGE: 2338422



/UG = Hs.79886 ribose 5-phosphate isomerase A (ribose 5-phosphate



epimerase)


212993_at
G protein-coupled receptor kinase 7


213026_at
APG12 autophagy 12-like (S. cerevisiae)


213029_at
son of sevenless homolog 1 (Drosophila) [BLAST]


213032_at
son of sevenless homolog 1 (Drosophila) [BLAST]


213041_s_at
ATP synthase, H+ transporting, mitochondrial F1 complex,



delta subunit


213050_at
activity-regulated cytoskeleton-associated protein


213051_at
low voltage-activated T-type calcium channel alpha-1



subunit (CACNA1I)


213057_at
ATP synthase mitochondrial F1 complex assembly factor 2



[BLAST]


213089_at
Consensus includes gb: AU158490 /FEA = EST



/DB_XREF = gi: 11020011 /DB_XREF = est: AU158490 /CLONE = PLACE3000042



/UG = Hs.303632 Human DNA sequence from clone RP11-110H4 on chromosome



5 Contains a pseudogene . . .


213145_at
nucleoporin 133 kD [BLAST]


213182_x_at
Consensus includes gb: R78668 /FEA = EST /DB_XREF = gi: 854949



/DB_XREF = est: yi74c04.r1 /CLONE = IMAGE: 144966 /UG = Hs.106070 cyclin-



dependent kinase inhibitor 1C (p57, Kip2)


213212_x_at
F-box only protein 21


213263_s_at
mitogen-activated protein kinase kinase kinase 12


213294_at
aldo-keto reductase family 1, member C1 (dihydrodiol



dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)


213313_at
nucleoporin 62 kD


213318_s_at
HLA-B associated transcript 3


213338_at
zinc finger protein 363


213360_s_at
chromosome 21 open reading frame 108


213378_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-



like helicase homolog, S. cerevisiae) -


213390_at
chromosome 19 open reading frame 7


213398_s_at
mitochondrial ribosomal protein S22


213400_s_at
transducin (beta)-like 1X-linked [BLAST]


213428_s_at
collagen, type VI, alpha 1


213505_s_at
C-type (calcium dependent, carbohydrate-recognition



domain) lectin, superfamily member 1 (cartilage-derived)


213518_at
RNA binding motif protein 15


213581_at
chromosome 21 open reading frame 67


213645_at
Consensus includes gb: AF305057 /DEF = Homo sapiens RTS



(RTS) gene, complete cds, alternatively spliced /FEA = mRNA_1



/DB_XREF = gi: 11094017 /UG = Hs.180433 rTS beta protein


213668_s_at
Consensus includes gb: AI989477 /FEA = EST



/DB_XREF = gi: 5836358 /DB_XREF = est: ws25b11.x1 /CLONE = IMAGE: 2498205



/UG = Hs.83484 SRY (sex determining region Y)-box 4


213670_x_at
chromosome 21 open reading frame 108


213682_at
Consensus includes gb: AL036344 /FEA = EST



/DB_XREF = gi: 5927743 /DB_XREF = est: DKFZp564A053_r1 /CLONE = DKFZp564A053



/UG = Hs.169329 DKFZP564A043 protein


213704_at
Rab geranylgeranyltransferase, beta subunit


213720_s_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily a, member 4 [BLAST]


213746_s_at
filamin A, alpha (actin binding protein 280) [BLAST]


213773_x_at
LUC7-like (S. cerevisiae)


213838_at
RAN binding protein 9


213842_x_at
Williams Beuren syndrome chromosome region 22


213887_s_at
polymerase (RNA) II (DNA directed) polypeptide E (25 kD)



[BLAST]


213892_s_at
adenine phosphoribosyltransferase


213923_at
RAP2B, member of RAS oncogene family


213947_s_at
Rho-related BTB domain containing 2 [BLAST]


213977_s_at
neuronal guanine nucleotide exchange factor


213998_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72 kD)


214022_s_at
interferon induced transmembrane protein 1 (9-27)


214035_x_at
nuclear pore complex interacting protein


214093_s_at
RNA polymerase I associated factor, 53 kD


214097_at
ribosomal protein S21


214100_x_at
LUC7-like (S. cerevisiae)


214113_s_at
RNA binding motif protein 8A


214149_s_at
Consensus includes gb: AI252582 /FEA = EST



/DB_XREF = gi: 3849111 /DB_XREF = est: qv25b02.x1 /CLONE = IMAGE: 1982571



/UG = Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton



pump) 9 kD


214246_x_at
cholinergic receptor, nicotinic, epsilon polypeptide


214259_s_at
aldo-keto reductase family 7, member A2 (aflatoxin



aldehyde reductase)


214356_s_at
pumilio homolog 2 (Drosophila)


214484_s_at
protease, serine, 16 (thymus)


214500_at
H2A histone family, member Y


214531_s_at
sorting nexin 1


214581_x_at
tumor necrosis factor receptor superfamily, member 21


214657_s_at
Consensus includes gb: AU134977 /FEA = EST



/DB_XREF = gi: 10995516 /DB_XREF = est: AU134977 /CLONE = PLACE1000926



/UG = Hs.322149 Human clone 137308 mRNA, partial cds


214679_x_at
Consensus includes gb: AL110227.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp434J194 (from clone DKFZp434J194). /FEA = mRNA



/DB_XREF = gi: 5817165 /UG = Hs.323067 Homo sapiens mRNA; cDNA



DKFZp434J194 (from clone . . .


214753_at
Consensus includes gb: AW084068 /FEA = EST



/DB_XREF = gi: 6039220 /DB_XREF = est: xc26c06.x1 /CLONE = IMAGE: 2585386



/UG = Hs.110630 Human BRCA2 region, mRNA sequence CG006


214911_s_at
Consensus includes gb: S78771.1 /DEF = NAT = CpG island-



associated gene human, mRNA, 1741 nt. /FEA = mRNA /DB_XREF = gi: 244232



/UG = Hs.75243 bromodomain-containing 2


214919_s_at
baculoviral IAP repeat-containing 6 (apollon)


215001_s_at
glutamate-ammonia ligase (glutamine synthase)


215089_s_at
Protein tyrosine phosphatase, receptor type, epsilon



polypeptide


215210_s_at
dihydrolipoamide S-succinyltransferase (E2 component of



2-oxo-glutarate complex)


215245_x_at
fragile X mental retardation 1 [BLAST]


215313_x_at
major histocompatibility complex, class I, A


215464_s_at
phosphoinositide-3-kinase, regulatory subunit 4, p150


215482_s_at
PRP31 pre-mRNA processing factor 31 homolog (yeast)


215498_s_at
mitogen-activated protein kinase kinase 3


215690_x_at
GPAA1P anchor attachment protein 1 homolog (yeast)


215696_s_at
aryl-hydrocarbon receptor nuclear translocator 2


215731_s_at
M-phase phosphoprotein 9


215807_s_at
plexin B1


215823_x_at
Consensus includes gb: U64661 /DEF = Human poly(A)-binding



protein processed pseudogene3 /FEA = mRNA /DB_XREF = gi: 1519214



/UG = Hs.283767 poly(A)-binding protein, cytoplasmic, pseudogene 3


215884_s_at
ubiquilin 2


216033_s_at
chromosome 20 open reading frame 100


216237_s_at
MCM5 minichromosome maintenance deficient 5, cell



division cycle 46 (S. cerevisiae) [BLAST]


216264_s_at
laminin, beta 2 (laminin S)


216384_x_at
Consensus includes gb: AF257099 /DEF = Homo sapiens



prothymosin alpha (PTMA) gene, complete cds /FEA = CDS



/DB_XREF = gi: 8037944 /UG = Hs.283947 Homo sapiens prothymosin alpha



(PTMA) gene, complete cds


216457_s_at
pecanex-like 3 (Drosophila)


216565_x_at
Consensus includes gb: AL121994 /DEF = Human DNA sequence



from clone RP4-781L3 on chromosome 1p34.3-36.11 Contains a pseudogene



similar to IFITM3 (interferon inducedntransmembrane protein 3 (1-



8U)), . . .


216620_s_at
Rho guanine nucleotide exchange factor (GEF) 10


216894_x_at
Consensus includes gb: D64137 /DEF = Human KIP2 gene for



Cdk-inhibitor p57KIP2, complete cds (exon1-4) /FEA = mRNA_4



/DB_XREF = gi: 992945 /UG = Hs.106070 cyclin-dependent kinase inhibitor 1C



(p57, Kip2)


216913_s_at
Rho-related BTB domain containing 2 [BLAST]


216952_s_at
lamin B2


217221_x_at
RNA binding motif protein 10


217301_x_at
retinoblastoma binding protein 4


217419_x_at
Consensus includes gb: AK021586.1 /DEF = Homo sapiens cDNA



FLJ11524 fis, clone HEMBA1002547, highly similar to Homo sapiens



agrin precursor mRNA. /FEA = mRNA /DB_XREF = gi: 10432794 /UG = Hs.273330



Homo s . . .


217718_s_at
mitochondrial ribosomal protein L42


217749_at
ring finger protein 12


217751_at
spastic paraplegia 3A (autosomal dominant)


217755_at
hematological and neurological expressed 1


217759_at
sperm associated antigen 10


217767_at
complement component 3


217770_at
tripartite motif-containing 33


217779_s_at
zinc finger, DHHC domain containing 7


217794_at
TAF7-like RNA polymerase II, TATA box binding protein



(TBP)-associated factor, 50 kD


217807_s_at
glioma tumor suppressor candidate region gene 2


217809_at
G protein-coupled receptor kinase-interactor 1


217836_s_at
chromosome 20 open reading frame 44


217906_at
cyclin D-type binding-protein 1


217914_at
nucleoporin 54 kD


217918_at
ORM1-like 2 (S. cerevisiae)


217957_at
ORM1-like 2 (S. cerevisiae)


217969_at
chromosome 11 open reading frame2


217973_at
hydroxyacid oxidase 2 (long chain)


217983_s_at
RTC domain containing 1


217984_at
RTC domain containing 1


218001_at
mitochondrial ribosomal protein S2 [BLAST]


218010_x_at
chromosome 20 open reading frame 149


218035_s_at
chromosome 20 open reading frame 16


218059_at
ribosomal protein L26-like 1


218076_s_at
solute carrier family 38, member 4


218083_at
prostaglandin E synthase 2


218090_s_at
gb: NM_018117.8 /DEF = Homo sapiens WD40 repeat domain 11



protein (WDR11), mRNA. /FEA = mRNA /GEN = WDR11 /PROD = WD40 repeat domain



11 protein /DB_XREF = gi: 13324687 /UG = Hs.16677 WD repeat domain 15



/FL = gb . . .


218096_at
chromosome 20 open reading frame 46


218112_at
mitochondrial ribosomal protein S34


218123_at
chromosome 21 open reading frame 59


218134_s_at
LUC7-like (S. cerevisiae)


218145_at
chromosome 20 open reading frame 97


218180_s_at
RNA binding motif protein 15


218205_s_at
eukaryotic translation initiation factor 2 alpha kinase 4


218220_at
chromosome 12 open reading frame 10


218228_s_at
tankyrase, TRF1-interacting ankyrin-related ADP-ribose



polymerase 2


218241_at
golgi autoantigen, golgin subfamily a, 5


218244_at
FK506 binding protein 14 (22 kDa)


218263_s_at
ras homolog gene family, member U


218294_s_at
PRP31 pre-mRNA processing factor 31 homolog (yeast)


218315_s_at
chromosome 20 open reading frame 34


218317_x_at
ganglioside-induced differentiation-associated protein 1-



like 1


218323_at
chromosome 15 open reading frame 12


218328_at
mitochondrial ribosomal protein S2


218366_x_at
WD repeat domain 13


218379_at
RNA binding motif protein 7


218388_at
6-phosphogluconolactonase


218391_at
dual specificity phosphatase 12


218415_at
vacuolar protein sorting 33B (yeast)


218437_s_at
leucine zipper transcription factor-like 1


218443_s_at
DAZ associated protein 1


218448_at
chromosome 20 open reading frame 11


218450_at
heme binding protein 1


218494_s_at
SLC2A4 regulator


218529_at
toll-like receptor 7


218592_s_at
cat eye syndrome chromosome region, candidate 5 [BLAST]


218652_s_at
protein phosphatase 1, regulatory (inhibitor) subunit 14D


218659_at
chromosome 20 open reading frame 36


218697_at
G-2 and S-phase expressed 1


218744_s_at
protein kinase C and casein kinase substrate in neurons 3


218755_at
RAB6 interacting, kinesin-like (rabkinesin6)


218756_s_at
matrix metalloproteinase 28


218767_at
chromosome 12 open reading frame 5


218773_s_at
kinesin-associated protein 3


218796_at
chromosome 20 open reading frame 42


218821_at
aminopeptidase-like 1


218839_at
hairy/enhancer-of-split related with YRPW motif 1


218848_at
MEF2-interacting transcription repressor


218856_at
mitochondrial ribosomal protein L35


218860_at
hypothetical protein, clone MTA.D02.090


218865_at
ATP synthase mitochondrial F1 complex assembly factor 1


218872_at
chromosome 20 open reading frame 11


218908_at
alveolar soft part sarcoma chromosome region, candidate 1


218921_at
testicular cell adhesion molecule 1


218983_at
immediate early response 5


218986_s_at
aldehyde reductase (aldose reductase) like 6


219007_at
hypothetical protein FLJ13287


219041_s_at
pre-B lymphocyte gene 3


219053_s_at
epsin 3


219066_at
mitochondrial ribosomal protein S35


219117_s_at
FK506 binding protein 11 (19 kDa)


219151_s_at
general transcription factor IIE, polypeptide 1 (alpha



subunit, 56 kD)


219165_at
arachidonate lipoxygenase 3


219166_at
mitochondrial ribosomal protein S18A


219188_s_at
chromosome 20 open reading frame 40


219192_at
vacuolar protein sorting 11 (yeast)


219203_at
chromosome 20 open reading frame 45


219357_at
mitochondrial ribosomal protein S28


219534_x_at
cyclin-dependent kinase inhibitor 1C (p57, Kip2)


219571_s_at
G protein-coupled receptor, family C, group 1, member B


219763_at
zinc finger protein 317


219764_at
frizzled homolog 10 (Drosophila)


219816_s_at
zinc finger, DHHC domain containing 4


219880_at
conserved intergenic sequence 2


219911_s_at
solute carrier family 21 (organic anion transporter),



member 12


219914_at
endothelin converting enzyme-like 1


220079_s_at
pecanex-like 3 (Drosophila)


220212_s_at
neuromedin U


220597_s_at
bridging integrator 3


220690_s_at
EGF-like-domain, multiple 6


220748_s_at
serine (or cysteine) proteinase inhibitor, clade A



(alpha-1 antiproteinase, antitrypsin), member 10


220925_at
transgene insertion A2, Pierre Coulombe


221050_s_at
GTP binding protein 2


221203_s_at
hypoxia-inducible factor 1, alpha subunit inhibitor


221264_s_at
Alpha1, 2-fucosyltransferase a [BLAST]


221269_s_at
SH3 domain binding glutamic acid-rich protein like 3



[BLAST]


221501_x_at
nuclear pore complex interacting protein


221509_at
density-regulated protein


221562_s_at
sirtuin silent mating type information regulation 2



homolog 3 (S. cerevisiae)


221647_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 35


221689_s_at
Down syndrome critical region gene 5


221699_s_at
ganglioside-induced differentiation-associated protein 1-



like 1 [BLAST]


221712_s_at
protocadherin beta 17 pseudogene [BLAST]


221725_at
WAS protein family, member 2


221750_at
Consensus includes gb: BG035985 /FEA = EST



/DB_XREF = gi: 12430666 /DB_XREF = est: 602326096F1 /CLONE = IMAGE: 4414319



/UG = Hs.77910 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1



(soluble)


221766_s_at
Consensus includes gb: AW246673 /FEA = EST



/DB_XREF = gi: 6589666 /DB_XREF = est: 2821951.3prime /CLONE = IMAGE: 2821951



/UG = Hs.10784 hypothetical protein FLJ20037


221786_at
Consensus includes gb: BF197222 /FEA = EST



/DB_XREF = gi: 11085906 /DB_XREF = est: 7m88b07.x1 /CLONE = IMAGE: 3561949



/UG = Hs.12342 Homo sapiens clone 24538 mRNA sequence


221789_x_at
solute carrier family 25 (mitochondrial oxodicarboxylate



carrier), member 21


221816_s_at
ankyrin repeat and SOCS box-containing 3 [BLAST]


221827_at
chromosome 20 open reading frame 18


221918_at
PCTAIRE protein kinase 2


221919_at
heterogeneous nuclear ribonucleoprotein A1


221931_s_at
chromosome 20 open reading frame 150


221932_s_at
insulin-like growth factor 2, antisense


221989_at
ribosomal protein L10


222010_at
acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl



Coenzyme A thiolase)


222011_s_at
acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl



Coenzyme A thiolase)


222037_at
MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)


222040_at
heterogeneous nuclear ribonucleoprotein A1


222122_s_at
retinoic acid induced 17 [BLAST]


222131_x_at
solute carrier family 25 (mitochondrial oxodicarboxylate



carrier), member 21


222154_s_at
golgi reassembly stacking protein 2, 55 kDa


222155_s_at
chromosome 1 open reading frame 28


222206_s_at
p21(CDKN1A)-activated kinase 6


222369_at
ribosomal protein L36a
















TABLE 3







genes down-regulated at day 2








Gene Name
Gene Description





1316_at
thyroid hormone receptor, alpha (erythroblastic leukemia



viral (v-erb-a) oncogene homolog, avian)


35150_at
tumor necrosis factor receptor superfamily, member 5


36829_at
period homolog 1 (Drosophila)


37793_r_at
RAD51-like 3 (S. cerevisiae)


47571_at
zinc finger protein 236


49327_at
sirtuin silent mating type information regulation 2



homolog 3 (S. cerevisiae)


48612_at
tubulin, beta polypeptide 4, member Q


58900_at
Kruppel-like factor 13


200706_s_at
fragile X mental retardation, autosomal homolog 2


200915_x_at
kinectin 1 (kinesin receptor)


200976_s_at
Tax1 (human T-cell leukemia virus type I) binding protein 1


201057_s_at
golgi autoantigen, golgin subfamily b, macrogolgin (with



transmembrane signal), 1


201070_x_at
splicing factor 3b, subunit 1, 155 kD


201140_s_at
RAB5C, member RAS oncogene family


201278_at
disabled homolog 2, mitogen-responsive phosphoprotein



(Drosophila)


201386_s_at
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 15


201567_s_at
golgi autoantigen, golgin subfamily a, 4


201686_x_at
apoptosis inhibitor 5


201878_at
ariadne homolog, ubiquitin-conjugating enzyme E2 binding



protein, 1 (Drosophila)


201884_at
carcinoembryonic antigen-related cell adhesion molecule 5


201971_s_at
ATPase, H+ transporting, lysosomal 70 kD, V1 subunit A,



isoform 1


202037_s_at
secreted frizzled-related protein 1


202071_at
syndecan 4 (amphiglycan, ryudocan)


202122_s_at
glycoprotein A33 (transmembrane)


202224_at
Consensus includes gb: BF304695 /FEA = EST



/DB_XREF = gi: 11251580 /DB_XREF = est: 601888248F1 /CLONE = IMAGE: 4122466



/UG = Hs.306088 v-crk avian sarcoma virus CT10 oncogene homolog



/FL = gb: D10656.1 gb: NM_016823.1


202340_x_at
nuclear receptor subfamily 4, group A, member 1


202488_s_at
FXYD domain-containing ion transport regulator 3


202604_x_at
a disintegrin and metalloproteinase domain 10


202668_at
ephrin-B2


202709_at
fibromodulin


202840_at
gb: NM_003487.1 /DEF = Homo sapiens TATA box binding protein



(TBP)-associated factor, RNA polymerase II, N, 68 kD (RNA-binding



protein 56) (TAF2N), mRNA. /FEA = mRNA /GEN = TAF2N /PROD = TATA box



binding . . .


202861_at
period homolog 1 (Drosophila)


202873_at
ATPase, H+ transporting, lysosomal 42 kD, V1 subunit C,



isoform 1


202902_s_at
cathepsin S


202921_s_at
ankyrin 2, neuronal


203134_at
phosphatidylinositol binding clathrin assembly protein


203243_s_at
transducin (beta)-like 3


203319_s_at
zinc finger protein 148 (pHZ-52)


203395_s_at
hairy homolog (Drosophila)


203511_s_at
potassium large conductance calcium-activated channel,



subfamily M beta member 3


203512_at
potassium large conductance calcium-activated channel,



subfamily M beta member 3


203666_at
stromal cell-derived factor 1


203758_at
cathepsin O


203788_s_at
sema domain, immunoglobulin domain (Ig), short basic



domain, secreted, (semaphorin) 3C


203875_at
SWI/SNF related, matrix associated, actin dependent



regulator of chromatin, subfamily a, member 1


203887_s_at
thrombomodulin


203922_s_at
cytochrome b-245, beta polypeptide (chronic granulomatous



disease)


203933_at
sema domain, immunoglobulin domain (Ig), short basic



domain, secreted, (semaphorin) 3E


203963_at
carbonic anhydrase XII


204042_at
WAS protein family, member 3


204230_s_at
solute carrier family 17 (sodium-dependent inorganic



phosphate cotransporter), member 7


204232_at
Fc fragment of IgE, high affinity I, receptor for; gamma



polypeptide


204243_at
rearranged L-myc fusion sequence


204312_x_at
cAMP responsive element binding protein 1


204421_s_at
gb: M27968.1 /DEF = Human basic fibroblast growth factor



(FGF) mRNA, complete cds. /FEA = mRNA /GEN = FGF2 /DB_XREF = gi: 182562



/UG = Hs.284244 fibroblast growth factor 2 (basic) /FL = gb: M27968.1



gb: NM_002006.1


204670_x_at
major histocompatibility complex, class II, DR beta 1


204762_s_at
guanine nucleotide binding protein (G protein), alpha



activating activity polypeptide O


204802_at
Ras-related associated with diabetes


204842_x_at
sperm autoantigenic protein 17


204906_at
ribosomal protein S6 kinase, 90 kD, polypeptide 2


204923_at
chromosome X open reading frame 9


205046_at
centromere protein E (312 kD)


205097_at
solute carrier family 26 (sulfate transporter), member 2


205166_at
calpain 5


205232_s_at
platelet-activating factor acetylhydrolase 2 (40 kD)


205235_s_at
M-phase phosphoprotein 1


205312_at
spleen focus forming virus (SFFV) proviral integration



oncogene spil


205328_at
claudin 10


205359_at
A kinase (PRKA) anchor protein 6


205370_x_at
dihydrolipoamide branched chain transacylase (E2



component of branched chain keto acid dehydrogenase complex; maple



syrup urine disease)


205381_at
mesothelin


205431_s_at
bone morphogenetic protein 5


205520_at
striatin, calmodulin binding protein


205525_at
gb: NM_018495.3 /DEF = Homo sapiens NAG22 protein



(LOC55873), mRNA. /FEA = mRNA /GEN = LOC55873 /PROD = NAG22 protein



/DB_XREF = gi: 13236500 /UG = Hs.283080 NAG22 protein /FL = gb: AF247820.3



gb: NM_018495.3


205595_at
desmoglein 3 (pemphigus vulgaris antigen)


205608_s_at
angiopoietin 1


205636_at
SH3-domain GRB2-like 3 [BLAST]


205729_at
oncostatin M receptor


205752_s_at
glutathione S-transferase M5


205879_x_at
ret proto-oncogene (multiple endocrine neoplasia and



medullary thyroid carcinoma 1, Hirschsprung disease)


205949_at
carbonic anhydrase I


205981_s_at
inhibitor of growth family, member 1-like


206096_at
zinc finger protein 35 (clone HF.10)


206169_x_at
MCF.2 cell line derived transforming sequence-like


206212_at
carboxypeptidase A2 (pancreatic)


206263_at
flavin containing monooxygenase 4


206291_at
neurotensin


206323_x_at
oligophrenin 1


206388_at
phosphodiesterase 3A, cGMP-inhibited


206389_s_at
phosphodiesterase 3A, cGMP-inhibited


206456_at
gamma-aminobutyric acid (GABA) A receptor, alpha 5


206551_x_at
transient receptor potential cation channel, subfamily M,



member 4


206586_at
cannabinoid receptor 2 (macrophage)


206766_at
integrin, alpha 10


206825_at
oxytocin receptor


206910_x_at
H factor (complement)-like 3


206936_x_at
chromosome 20 open reading frame 110


207041_at
mannan-binding lectin serine protease 2


207064_s_at
amine oxidase, copper containing 2 (retina-specific)


207131_x_at
gamma-glutamyltransferase 1


207152_at
neurotrophic tyrosine kinase, receptor, type 2


207300_s_at
coagulation factor VII (serum prothrombin conversion



accelerator)


207347_at
excision repair cross-complementing rodent repair



deficiency, complementation group 6


207365_x_at
kinetochore associated 1


207389_at
glycoprotein Ib (platelet), alpha polypeptide


207408_at
organic cationic transporter-like 4


207608_x_at
cytochrome P450, subfamily I (aromatic compound-



inducible), polypeptide 2


207730_x_at
chromosome 20 open reading frame 11


207732_s_at
discs, large (Drosophila) homolog 3 (neuroendocrine-dlg)


207734_at
elongation of very long chain fatty acids (FEN1/Elo2,



SUR4/Elo3, yeast)-like 2


207755_at
chromosome 20 open reading frame 48


207908_at
keratin 2A (epidermal ichthyosis bullosa of Siemens)


207936_x_at
ret finger protein-like 3


207938_at
protease inhibitor 15


207953_at
Consensus includes gb: AF010144.1 /DEF = Homo sapiens



neuronal thread protein AD7c-NTP mRNA, complete cds. /FEA = mRNA



/PROD = neuronal thread protein AD7c-NTP /DB_XREF = gi: 3002526



/UG = Hs.129735 neuronal . . .


207969_x_at
acrosomal vesicle protein 1 [BLAST]


208120_x_at
gb: NM_031221.1 /DEF = Homo sapiens hypothetical protein



FKSG63 (FKSG63), mRNA. /FEA = mRNA /GEN = FKSG63 /PROD = hypothetical



protein FKSG63 /DB_XREF = gi: 13654297 /FL = gb: NM_031221.1


208124_s_at
sema domain, immunoglobulin domain (Ig), transmembrane



domain (TM) and short cytoplasmic domain, (semaphorin) 4F


208137_x_at
gb: NM_030972.1 /DEF = Homo sapiens hypothetical protein



MGC5384 (MGC5384), mRNA. /FEA = mRNA /GEN = MGC5384 /PROD = hypothetical



protein MGC5384 /DB_XREF = gi: 13775165 /FL = gb: NM_030972.1


208138_at
gastrin


208185_x_at
Consensus includes gb: NM_016415.1 /DEF = Homo sapiens clone



FLB3816 (LOC51216), mRNA. /FEA = mRNA /GEN = LOC51216 /PROD = clone FLB3816



/DB_XREF = gi: 10047109 /UG = Hs.277887 clone FLB3816 /FL = gb: NM_016415.1



. . .


208238_x_at
protocadherin beta 1


208246_x_at
protein phosphatase 1, regulatory (inhibitor) subunit 12C


208306_x_at
major histocompatibility complex, class II, DR beta 4


208351_s_at
mitogen-activated protein kinase 1


208360_s_at
gb: NM_015870.1 /DEF = Homo sapiens endogenous retrovirus H



D1 leader regionintegrase-derived ORF1, ORF2, and putative envelope



protein (HSU88895), mRNA. /FEA = mRNA /GEN = HSU88895 /PROD = endogenous



re . . .


208382_s_at
DMC1 dosage suppressor of mck1 homolog, meiosis-specific



homologous recombination (yeast)


208447_s_at
phosphoribosyl pyrophosphate synthetase 1


208486_at
cytochrome P450, subfamily IVA, polypeptide 11 [BLAST]


208520_at
olfactory receptor, family 10, subfamily H, member 3


208730_x_at
RAB2, member RAS oncogene family


208763_s_at
delta sleep inducing peptide, immunoreactor


208860_s_at
alpha thalassemia/mental retardation syndrome X-linked



(RAD54 homolog, S. cerevisiae)


208868_s_at
GABA(A) receptor-associated protein like 1


208869_s_at
GABA(A) receptor-associated protein like 1


209312_x_at
gb: U65585.1 /DEF = Homo sapiens MHC class II antigen (HLA-



DRB1) mRNA, HLA-DRB1*PBL allele, complete cds. /FEA = mRNA /GEN = HLA-



DRB1 /PROD = MHC class II antigen /DB_XREF = gi: 5478215 /UG = Hs.180255



major . . .


209436_at
spondin 1, (f-spondin) extracellular matrix protein


209535_s_at
LIM and SH3 protein 1


209701_at
desmin [BLAST]


209703_x_at
component of oligomeric golgi complex 4


209790_s_at
caspase 6, apoptosis-related cysteine protease [BLAST]


209875_s_at
secreted phosphoprotein 1 (osteopontin, bone sialoprotein



I, early T-lymphocyte activation 1)


209882_at
Ric-like, expressed in many tissues (Drosophila)


209913_x_at
synaptosomal-associated protein, 91 kD homolog (mouse)


210048_at
N-ethylmaleimide-sensitive factor attachment protein,



gamma


210226_at
nuclear receptor subfamily 4, group A, member 1


210412_at
glutamate receptor, ionotropic, N-methyl D-aspartate 2B


210686_x_at
gb: BC001407.1 /DEF = Homo sapiens, Similar to cytochrome c-



like antigen, clone MGC: 2960, mRNA, complete cds. /FEA = mRNA



/PROD = Similar to cytochrome c-like antigen /DB_XREF = gi: 12655110



/UG = Hs. 253070 . . .


210739_x_at
solute carrier family 4, sodium bicarbonate



cotransporter, member 4


210757_x_at
disabled homolog 2, mitogen-responsive phosphoprotein



(Drosophila)


210796_x_at
sialic acid binding Ig-like lectin 6


210836_x_at
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3



dunce homolog, Drosophila)


210837_s_at
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3



dunce homolog, Drosophila)


210912_x_at
glutathione S-transferase M4


210923_at
chromosome 20 open reading frame 82


210944_s_at
calpain 3, (p94)


210962_s_at
A kinase (PRKA) anchor protein (yotiao) 9


211014_s_at
promyelocytic leukemia


211026_s_at
monoglyceride lipase [BLAST]


211040_x_at
gb: BC006325.1 /DEF = Homo sapiens, G-2 and S-phase



expressed 1, clone MGC: 12560, mRNA, complete cds. /FEA = mRNA /PROD = G-



2 and S-phase expressed 1 /DB_XREF = gi: 13623450 /FL = gb: BC006325.1


211071_s_at
chromosome 12 open reading frame 8 [BLAST]


211074_at
gb: AF000381.1 /DEF = Homo sapiens non-functional folate



binding protein mRNA, complete cds. /FEA = mRNA /PROD = non-functional



folate binding protein /DB_XREF = gi: 2565195 /FL = gb: AF000381.1


211096_at
pre-B-cell leukemia transcription factor 2


211113_s_at
ATP-binding cassette, sub-family G (WHITE), member 1


211139_s_at
NGFI-A binding protein 1 (EGR1 binding protein 1)


211277_x_at
amyloid beta (A4) precursor protein (protease nexin-II,



Alzheimer disease)


211316_x_at
CASP8 and FADD-like apoptosis regulator


211323_s_at
inositol 1,4,5-triphosphate receptor, type 1


211328_x_at
hemochromatosis


211364_at
methylthioadenosine phosphorylase


211416_x_at
gamma-glutamyltransferase 1


211452_x_at
leucine rich repeat (in FLII) interacting protein 1



[BLAST]


211460_at
testis-specific transcript, Y-linked 9


211464_x_at
caspase 6, apoptosis-related cysteine protease


211504_x_at
Rho-associated, coiled-coil containing protein kinase 2


211574_s_at
membrane cofactor protein (CD46, trophoblast-lymphocyte



cross-reactive antigen)


211657_at
carcinoembryonic antigen-related cell adhesion molecule 6



(non-specific cross reacting antigen) [BLAST]


211685_s_at
neurocalcin delta [BLAST]


211693_at
[BLAST]


211713_x_at
histone deacetylase 4 [BLAST]


211768_at
gb: BC006080.1 /DEF = Homo sapiens, Williams-Beuren syndrome



chromosome region 5, clone MGC: 12566, mRNA, complete cds. /FEA = mRNA



/PROD = Williams-Beuren syndrome chromosome region 5 /DB_XREF = gi: 13543



. . .


211769_x_at
tumor differentially expressed 1 [BLAST]


211781_x_at
gb: BC006164.1 /DEF = Homo sapiens, clone MGC: 13219, mRNA,



complete cds. /FEA = mRNA /PROD = Unknown (protein for MGC: 13219)



/DB_XREF = gi: 13544062 /FL = gb: BC006164.1


211801_x_at
hypoxia-inducible factor 1, alpha subunit inhibitor


211810_s_at
galactosylceramidase (Krabbe disease)


211814_s_at
cyclin E2


211918_x_at
placenta-specific 3 [BLAST]


212196_at
tumor necrosis factor receptor superfamily, member 19-



like [BLAST]


212233_at
chromosome 1 open reading frame 2


212514_x_at
Consensus includes gb: R60068 /FEA = EST /DB_XREF = gi: 830763



/DB_XREF = est: yh12h07.s1 /CLONE = IMAGE: 43138 /UG = Hs.147916 DEADH (Asp-



Glu-Ala-AspHis) box polypeptide 3


212736_at
Consensus includes gb: BE299456 /FEA = EST



/DB_XREF = gi: 9183204 /DB_XREF = est: 600944717T1 /CLONE = IMAGE: 2960548



/UG = Hs.6349 Human Chromosome 16 BAC clone CIT987SK-A-362G6


212876_at
UDP-Gal: betaGlcNAc beta 1,4-galactosyltransferase,



polypeptide 4


212884_x_at
apolipoprotein E [BLAST]


213109_at
myelin transcription factor 1-like


213193_x_at
T cell receptor beta locus


213270_at
membrane protein, palmitoylated 2 (MAGUK p55 subfamily



member 2) [BLAST]


213297_at
nucleolar protein family A, member 2 (H/ACA small



nucleolar RNPs)


213307_at
Consensus includes gb: AF131790.1 /DEF = Homo sapiens clone



24903 mRNA sequence. /FEA = mRNA /DB_XREF = gi: 4406618 /UG = Hs.12696



cortactin SH3 domain-binding protein


213406_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 1


213486_at
retinoic acid induced 17 [BLAST]


213816_s_at
met proto-oncogene (hepatocyte growth factor receptor)


213936_x_at
surfactant, pulmonary-associated protein B


214007_s_at
protein tyrosine kinase 9 [BLAST]


214336_s_at
coatomer protein complex, subunit alpha


214421_x_at
cytochrome P450, subfamily IIC (mephenytoin 4-



hydroxylase), polypeptide 9 [BLAST]


214558_at
G protein-coupled receptor 12


214594_x_at
ATPase, Class I, type 8B, member 1


214656_x_at
myosin IC


214698_at
Consensus includes gb: AW190873 /FEA = EST



/DB_XREF = gi: 6465353 /DB_XREF = est: x166a01.x1 /CLONE = IMAGE: 2679624



/UG = Hs.145078 regulator of differentiation (in S. pombe) 1


214707_x_at
Alstrom syndrome 1


214715_x_at
Consensus includes gb: AK024789.1 /DEF = Homo sapiens cDNA:



FLJ21136 fis, clone CAS07469. /FEA = mRNA /DB_XREF = gi: 10437175



/UG = Hs.206882 Homo sapiens mRNA for FLJ00032 protein, partial cds


214720_x_at
Consensus includes gb: BF981643 /FEA = EST



/DB_XREF = gi: 12384455 /DB_XREF = est: 602305961F1 /CLONE = IMAGE: 4397295



/UG = Hs.79844 DKFZP564M1416 protein


214849_at
Consensus includes gb: AW500220 /FEA = EST



/DB_XREF = gi: 7112628 /DB_XREF = est: UI-HF-BN0-akd-c-02-0-UI.r1



/CLONE = IMAGE: 3076610 /UG = Hs.332496 Human DNA sequence from clone



108K11 on chromosome 6p21 Cont . . .


214902_x_at
Consensus includes gb: AL080232.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp586A061 (from clone DKFZp586A061). /FEA = mRNA



/DB_XREF = gi: 5262725 /UG = Hs.220696 Homo sapiens mRNA; cDNA



DKFZp586A061 (from clone . . .


214906_x_at
ATPase, H+ transporting, lysosomal 31 kD, V1 subunit E



isoform 2


214923_at
Consensus includes gb: AK001155.1 /DEF = Homo sapiens cDNA



FLJ10293 fis, clone NT2RM1000280, highly similar to VACUOLAR ATP



SYNTHASE SUBUNIT D (EC 3.6.1.34). /FEA = mRNA /DB_XREF = gi: 7022230



/UG = Hs.30 . . .


214933_at
calcium channel, voltage-dependent, P/Q type, alpha 1A



subunit


214951_at
UDP-N-acetyl-alpha-D-galactosamine: (N-acetylneuraminyl)-



galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-



T)


214953_s_at
amyloid beta (A4) precursor protein (protease nexin-II,



Alzheimer disease)


215032_at
nudix (nucleoside diphosphate linked moiety X)-type motif



11


215067_x_at
chromosome 20 open reading frame 48


215178_x_at
N-acylsphingosine amidohydrolase (acid ceramidase)-like


215179_x_at
carboxypeptidase N, polypeptide 1, 50 kD


215236_s_at
phosphatidylinositol binding clathrin assembly protein


215366_at
sorting nexin 6


215373_x_at
chromosome 20 open reading frame 48


215383_x_at
Consensus includes gb: AL137312.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp761K23121 (from clone DKFZp761K23121). /FEA = mRNA



/DB_XREF = gi: 6807797 /UG = Hs.293681 Homo sapiens mRNA; cDNA



DKFZp761K23121 (from . . .


215404_x_at
prostate tumor over expressed gene 1


215439_x_at
F-box and leucine-rich repeat protein 11


215467_x_at
empty spiracles homolog 1 (Drosophila)


215479_at
immunoglobulin superfamily, member 9 [BLAST]


215511_at
Consensus includes gb: U19345.1 /DEF = Homo sapiens AR1



(TCF20) mRNA, partial cds. /FEA = mRNA /GEN = TCF20 /PROD = AR1



/DB_XREF = gi: 2924754 /UG = Hs.201668 transcription factor 20 (AR1)


215529_x_at
RecQ protein-like (DNA helicase Q1-like)


215553_x_at
chromosome 6 open reading frame 22


215587_x_at
chromosome 20 open reading frame 48


215588_x_at
Consensus includes gb: AK024958.1 /DEF = Homo sapiens cDNA:



FLJ21305 fis, clone COL02124. /FEA = mRNA /DB_XREF = gi: 10437382



/UG = Hs.287658 Homo sapiens cDNA: FLJ21305 fis, clone COL02124


215604_x_at
optic atrophy 3 (autosomal recessive, with chorea and



spastic paraplegia)


215609_at
Consensus includes gb: AK023895.1 /DEF = Homo sapiens cDNA



FLJ13833 fis, clone THYRO1000676. /FEA = mRNA /DB_XREF = gi: 10435969



/UG = Hs.296745 Homo sapiens cDNA FLJ13833 fis, clone THYRO1000676


215628_x_at
Consensus includes gb: AL049285.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp564M193 (from clone DKFZp564M193). /FEA = mRNA



/DB_XREF = gi: 4500045 /UG = Hs.302053 Homo sapiens mRNA; cDNA



DKFZp564M193 (from clone . . .


215766_at
Consensus includes gb: AL096729.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp434D044 (from clone DKFZp434D044). /FEA = mRNA



/DB_XREF = gi: 5419863 /UG = Hs.146581 Homo sapiens mRNA; cDNA



DKFZp434D044 (from clone . . .


215825_at
Consensus includes gb: AF070579.1 /DEF = Homo sapiens clone



24487 mRNA sequence. /FEA = mRNA /DB_XREF = gi: 3387951 /UG = Hs.283819 Homo



sapiens clone 24487 mRNA sequence


215856_at
Consensus includes gb: AK025833.1 /DEF = Homo sapiens cDNA:



FLJ22180 fis, clone HRC00936. /FEA = mRNA /DB_XREF = gi: 10438467



/UG = Hs.287692 Homo sapiens cDNA: FLJ22180 fis, clone HRC00936


215910_s_at
carbohydrate (chondroitin) synthase 1


215978_x_at
Consensus includes gb: AK021514.1 /DEF = Homo sapiens cDNA



FLJ11452 fis, clone HEMBA1001435. /FEA = mRNA /DB_XREF = gi: 10432710



/UG = Hs.148598 Homo sapiens cDNA FLJ11452 fis, clone HEMBA1001435


216051_x_at
Consensus includes gb: AK022045.1 /DEF = Homo sapiens cDNA



FLJ11983 fis, clone HEMBB1001337. /FEA = mRNA /DB_XREF = gi: 10433364



/UG = Hs.193162 Homo sapiens cDNA FLJ11983 fis, clone HEMBB1001337


216061_x_at
platelet-derived growth factor beta polypeptide (simian



sarcoma viral (v-sis) oncogene homolog)


216159_s_at
prostate tumor over expressed gene 1


216187_x_at
Consensus includes gb: AF222691.1 /DEF = Homo sapiens Alu



repeat (LNX1) mRNA sequence. /FEA = mRNA /DB_XREF = gi: 12655850



/UG = Hs.307008 Homo sapiens Alu repeat (LNX1) mRNA sequence


216196_at
chromosome 20 open reading frame 136 [BLAST]


216220_s_at
adenosine A1 receptor


216229_x_at
Consensus includes gb: X81001.1 /DEF = H. sapiens HCG II



mRNA. /FEA = mRNA /DB_XREF = gi: 531407 /UG = Hs.69707 HCGII-7 protein


216292_at
Consensus includes gb: AK024455.1 /DEF = Homo sapiens mRNA



for FLJ00047 protein, partial cds. /FEA = mRNA /GEN = FLJ00047



/PROD = FLJ00047 protein /DB_XREF = gi: 10440423 /UG = Hs.287753 Homo



sapiens mRNA for . . .


216294_s_at
ubiquitin specific protease 24


216374_at
Consensus includes gb: AC006986 /DEF = Homo sapiens BAC



clone RP11-155J5 from Y /FEA = CDS /DB_XREF = gi: 4753246 /UG = Hs.283908



Homo sapiens BAC clone RP11-155J5 from Y


216453_at
chromosome 20 open reading frame 4 [BLAST]


216459_x_at
Consensus includes gb: AL137624.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp434M1812 (from clone DKFZp434M1812). /FEA = mRNA



/DB_XREF = gi: 6808420 /UG = Hs.306476 Homo sapiens mRNA; cDNA



DKFZp434M1812 (from clo . . .


216524_x_at
Consensus includes gb: AL049260.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp564E233 (from clone DKFZp564E233). /FEA = mRNA



/DB_XREF = gi: 4500007 /UG = Hs.302050 Homo sapiens mRNA; cDNA



DKFZp564E233 (from clone . . .


216661_x_at
cytochrome P450, subfamily IIC (mephenytoin 4-



hydroxylase), polypeptide 9


216735_x_at
prostate tumor over expressed gene 1 [BLAST]


216745_x_at
Consensus includes gb: AK024606.1 /DEF = Homo sapiens cDNA:



FLJ20953 fis, clone ADSE01979. /FEA = mRNA /DB_XREF = gi: 10436920



/UG = Hs.306697 Homo sapiens cDNA: FLJ20953 fis, clone ADSE01979


216791_at
lysyl oxidase-like 4 [BLAST]


216859_x_at
Consensus includes gb: AL080112.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp586H0722 (from clone DKFZp586H0722). /FEA = mRNA



/DB_XREF = gi: 5262539 /UG = Hs.332731 Homo sapiens mRNA; cDNA



DKFZp586H0722 (from clo . . .


216873_s_at
ATPase, Class I, type 8B, member 2


216936_at
Consensus includes gb: X81637.1 /DEF = H. sapiens clathrin



light chain b gene. /FEA = mRNA /DB_XREF = gi: 963046 /UG = Hs.73919



clathrin, light polypeptide (Lcb)


216993_s_at
Consensus includes gb: U32169 /DEF = Human pro-a2 chain of



collagen type XI (COL11A2) gene, complete cds /FEA = mRNA_3



/DB_XREF = gi: 1000744 /UG = Hs.121509 collagen, type XI, alpha 2


217020_at
retinoic acid receptor, beta


217052_x_at
Consensus includes gb: AK024108.1 /DEF = Homo sapiens cDNA



FLJ14046 fis, clone HEMBA1006461. /FEA = mRNA /DB_XREF = gi: 10436406



/UG = Hs.142677 Homo sapiens cDNA FLJ14046 fis, clone HEMBA1006461


217117_x_at
Consensus includes gb: AF007194.1 /DEF = Homo sapiens mucin



(MUC3) mRNA, partial cds. /FEA = mRNA /GEN = MUC3 /PROD = mucin



/DB_XREF = gi: 2853300 /UG = Hs.129782 mucin 3A, intestinal


217189_s_at
chromosome 1 open reading frame 16


217269_s_at
protease, serine, 7 (enterokinase)


217315_s_at
kallikrein 13


217377_x_at
ets variant gene 6 (TEL oncogene)


217446_x_at
Consensus includes gb: AL080160.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp434M054 (from clone DKFZp434M054). /FEA = mRNA



/DB_XREF = gi: 5262622 /UG = Hs.274517 Homo sapiens mRNA; cDNA



DKFZp434M054 (from clone . . .


217457_s_at
RAP1, GTP-GDP dissociation stimulator 1


217465_at
NCK-associated protein 1 [BLAST]


217480_x_at
G protein-coupled receptor 2


217579_x_at
activity-distance traveled 4


217629_at
chromosome 22 open reading frame 20


217643_x_at
Consensus includes gb: AA443771 /FEA = EST



/DB_XREF = gi: 2156446 /DB_XREF = est: zw95f08.s1 /CLONE = IMAGE: 784743



/UG = Hs.270138 ESTs


217679_x_at
N-acetylglucosamine kinase


217703_x_at
Consensus includes gb: AA401963 /FEA = EST



/DB_XREF = gi: 2055965 /DB_XREF = est: zu53c08.s1 /CLONE.IMAGE: 741710



/UG = Hs.194107 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ



SEQUENCE CONTAMINATIO . . .


217713_x_at
chromosome 20 open reading frame 43


217715_x_at
thymidine kinase 2, mitochondrial


217787_s_at
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-



acetylgalactosaminyltransferase 2 (GalNAc-T2)


217859_s_at
synaptojanin 2 binding protein


217862_at
protein inhibitor of activated STAT, 1


217878_s_at
Consensus includes gb: AI203880 /FEA = EST



/DB_XREF = gi: 3756486 /DB_XREF = est: qf77g07.x1 /CLONE = IMAGE: 1756092



/UG = Hs.172405 cell division cycle 27 /FL = gb: NM_001256.1


218155_x_at
zinc finger protein 334


218211_s_at
transgene insertion 202, William Muller


218554_s_at
solute carrier family 22 (organic anion/cation



transporter), member 11


218820_at
LIM homeobox 9


218949_s_at
chromosome 15 open reading frame 12


219014_at
toll-like receptor 8


219183_s_at
pleckstrin homology, Sec7 and coiled/coil domains 4


219194_at
sema domain, immunoglobulin domain (Ig), transmembrane



domain (TM) and short cytoplasmic domain, (semaphorin) 4G


219206_x_at
mitochondrial ribosomal protein L48


219221_at
engulfment and cell motility 3 (ced-12 homolog, C. elegans)


219228_at
chromosome Y open reading frame 14


219290_x_at
dual adaptor of phosphotyrosine and 3-phosphoinositides


219398_at
zinc finger protein 338


219472_at
matrix metalloproteinase 28


219508_at
glucosaminyl (N-acetyl) transferase 3, mucin type


219677_at
UDP-glucuronate decarboxylase 1


219679_s_at
gb: NM_018604.1 /DEF = Homo sapiens hypothetical protein



PR01741 (PRO1741), mRNA. /FEA = mRNA /GEN = PRO1741 /PROD = hypothetical



protein PRO1741 /DB_XREF = gi: 8924074 /UG = Hs.306067 hypothetical



protein PRO . . .


219702_at
placenta-specific 1


219860_at
chromosome 6 open reading frame 20


219910_at
coronin, actin binding protein, 1A


219977_at
aryl hydrocarbon receptor interacting protein-like 1


220071_x_at
fidgetin


220113_x_at
lysyl oxidase-like 4


220115_s_at
gb: NM_006727.1 /DEF = Homo sapiens cadherin 10, type 2 (T2-



cadherin) (CDH10), mRNA. /FEA = mRNA /GEN = CDH10 /PROD = cadherin 10, type



2 (T2-cadherin) /DB_XREF = gi: 5802995 /UG = Hs.92489 cadherin 10, type 2 . . .


220232_at
chromosome 20 open reading frame 39


220252_x_at
optic atrophy 3 (autosomal recessive, with chorea and



spastic paraplegia)


220287_at
a disintegrin-like and metalloprotease (reprolysin type)



with thrombospondin type 1 motif, 9


220352_x_at
gb: NM_024305.1 /DEF = Homo sapiens hypothetical protein



MGC4278 (MGC4278), mRNA. /FEA = mRNA /GEN = MGC4278 /PROD = hypothetical



protein MGC4278 /DB_XREF = gi: 13236535 /UG = Hs.318780 hypothetical



protein MG . . .


220398_at
matrix metalloproteinase 28


220446_s_at
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4


220452_x_at
gb: NM_021031.1 /DEF = Homo sapiens cytochrome c-like



antigen (CYCL), mRNA. /FEA = mRNA /GEN = CYCL /PROD = cytochrome c-like



antigen /DB_XREF = gi: 10518341 /UG = Hs.262219 cytochrome c-like antigen



/FL = gb: NM . . .


220560_at
chromosome 11 open reading frame 21


220574_at
chromosome 20 open reading frame 48


220591_s_at
optic atrophy 3 (autosomal recessive, with chorea and



spastic paraplegia)


220671_at
CCR4 carbon catabolite repression 4-like (S. cerevisiae)


220684_at
T-box 21


220720_x_at
tubulin, alpha 4


220725_x_at
UDP-glucuronate decarboxylase 1


220776_at
potassium inwardly-rectifying channel, subfamily J,



member 14


220796_x_at
brain and acute leukemia, cytoplasmic


220800_s_at
tropomodulin 3 (ubiquitous)


220833_at
myosin XVA


220838_at
chromosome 20 open reading frame 21


220853_at
Kruppel-like factor 15


220944_at
RAB25, member RAS oncogene family


221078_s_at
LUC7-like (S. cerevisiae)


221107_at
cholinergic receptor, nicotinic, alpha polypeptide 9


221155_x_at
DnaJ (Hsp40) homolog, subfamily A, member 4


221192_x_at
matrix metalloproteinase 28


221220_s_at
hypoxia-inducible factor 1, alpha subunit inhibitor


221419_s_at
gb: NM_013307.1 /DEF = Homo sapiens non-functional folate



binding protein (HSAF000381), mRNA. /FEA = CDS /GEN = HSAF000381



/PROD = non-functional folate binding protein /DB_XREF = gi: 7019412



/FL = gb: NM_013307.1


221443_x_at
protease inhibitor 15


221460_at
olfactory receptor, family 2, subfamily C, member 1


221473_x_at
tumor differentially expressed 1


221541_at
espin


221695_s_at
mitogen-activated protein kinase kinase kinase 2 [BLAST]


221717_at
G protein-coupled receptor 52


221757_at
chromosome 20 open reading frame 54


221832_s_at
cysteine and tyrosine-rich 1 [BLAST]


221917_s_at
G-rich RNA sequence binding factor 1


221997_s_at
Ca<2+>dependent activator protein for secretion [BLAST]


222252_x_at
chromosome 1 open reading frame 6


222368_at
Consensus includes gb: AW972351 /FEA = EST



/DB_XREF = gi: 8162197 /DB_XREF = est: EST384442 /UG = Hs.293451 ESTs


222370_x_at
RAS, guanyl releasing protein 4
















TABLE 4







genes down-regulated at day 5








Gene Name
Gene Description





1316_at
thyroid hormone receptor, alpha (erythroblastic leukemia



viral (v-erb-a) oncogene homolog, avian)


35150_at
tumor necrosis factor receptor superfamily, member 5


36829_at
period homolog 1 (Drosophila)


37793_r_at
RAD51-like 3 (S. cerevisiae)


47571_at
zinc finger protein 236


49327_at
sirtuin silent mating type information regulation 2



homolog 3 (S. cerevisiae)


48612_at
tubulin, beta polypeptide 4, member Q


58900_at
Kruppel-like factor 13


200706_s_at
fragile X mental retardation, autosomal homolog 2


200776_s_at
syndecan 3 (N-syndecan)


200915_x_at
kinectin 1 (kinesin receptor)


200976_s_at
Tax1 (human T-cell leukemia virus type I) binding protein 1


201041_s_at
dual specificity phosphatase 1


201044_x_at
dual specificity phosphatase 1


201057_s_at
golgi autoantigen, golgin subfamily b, macrogolgin (with



transmembrane signal), 1


201070_x_at
splicing factor 3b, subunit 1, 155 kD


201140_s_at
RAB5C, member RAS oncogene family


201278_at
disabled homolog 2, mitogen-responsive phosphoprotein



(Drosophila)


201502_s_at
nuclear factor of kappa light polypeptide gene enhancer



in B-cells inhibitor, alpha


201567_s_at
golgi autoantigen, golgin subfamily a, 4


201686_x_at
apoptosis inhibitor 5


201876_at
paraoxonase 2


201878_at
ariadne homolog, ubiquitin-conjugating enzyme E2 binding



protein, 1 (Drosophila)


201884_at
carcinoembryonic antigen-related cell adhesion molecule 5


201971_s_at
ATPase, H+ transporting, lysosomal 70 kD, V1 subunit A,



isoform 1


202037_s_at
secreted frizzled-related protein 1


202071_at
syndecan 4 (amphiglycan, ryudocan)


202122_s_at
glycoprotein A33 (transmembrane)


202224_at
Consensus includes gb: BF304695 /FEA = EST



/DB_XREF = gi: 11251580 /DB_XREF = est: 601888248F1 /CLONE = IMAGE: 4122466



/UG = Hs.306088 v-crk avian sarcoma virus CT10 oncogene homolog



/FL = gb: D10656.1 gb: NM_016823.1


202488_s_at
FXYD domain-containing ion transport regulator 3


202604_x_at
a disintegrin and metalloproteinase domain 10


202709_at
fibromodulin


202840_at
gb: NM_003487.1 /DEF = Homo sapiens TATA box binding protein



(TBP)-associated factor, RNA polymerase II, N, 68 kD (RNA-binding



protein 56) (TAF2N), mRNA. /FEA = mRNA /GEN = TAF2N /PROD = TATA box



binding . . .


202861_at
period homolog 1 (Drosophila)


202873_at
ATPase, H+ transporting, lysosomal 42 kD, V1 subunit C,



isoform 1


202902_s_at
cathepsin S


202921_s_at
ankyrin 2, neuronal


203134_at
phosphatidylinositol binding clathrin assembly protein


203243_s_at
transducin (beta)-like 3


203319_s_at
zinc finger protein 148 (pHZ-52)


203395_s_at
hairy homolog (Drosophila)


203511_s_at
potassium large conductance calcium-activated channel,



subfamily M beta member 3


203512_at
potassium large conductance calcium-activated channel,



subfamily M beta member 3


203666_at
stromal cell-derived factor 1


203758_at
cathepsin O


203788_s_at
sema domain, immunoglobulin domain (Ig), short basic



domain, secreted, (semaphorin) 3C


203887_s_at
thrombomodulin


203922_s_at
cytochrome b-245, beta polypeptide (chronic granulomatous



disease)


203933_at
sema domain, immunoglobulin domain (Ig), short basic



domain, secreted, (semaphorin) 3E


203963_at
carbonic anhydrase XII


204042_at
WAS protein family, member 3


204230_s_at
solute carrier family 17 (sodium-dependent inorganic



phosphate cotransporter), member 7


204232_at
Fc fragment of IgE, high affinity I, receptor for; gamma



polypeptide


204243_at
rearranged L-myc fusion sequence


204312_x_at
cAMP responsive element binding protein 1


204360_s_at
N-acetylglucosaminidase, alpha-(Sanfilippo disease IIIB)


204421_s_at
gb: M27968.1 /DEF = Human basic fibroblast growth factor



(FGF) mRNA, complete cds. /FEA = mRNA /GEN = FGF2 /DB_XREF = gi: 182562



/UG = Hs.284244 fibroblast growth factor 2 (basic) /FL = gb: M27968.1



gb: NM_002006.1


204670_x_at
major histocompatibility complex, class II, DR beta 1


204762_s_at
guanine nucleotide binding protein (G protein), alpha



activating activity polypeptide O


204802_at
Ras-related associated with diabetes


204842_x_at
sperm autoantigenic protein 17


205046_at
centromere protein E (312 kD)


205097_at
solute carrier family 26 (sulfate transporter), member 2


205232_s_at
platelet-activating factor acetylhydrolase 2 (40 kD)


205235_s_at
M-phase phosphoprotein 1


205328_at
claudin 10


205359_at
A kinase (PRKA) anchor protein 6


205381_at
mesothelin


205431_s_at
bone morphogenetic protein 5


205520_at
striatin, calmodulin binding protein


205525_at
gb: NM_018495.3 /DEF = Homo sapiens NAG22 protein



(LOC55873), mRNA. /FEA = mRNA /GEN = LOC55873 /PROD = NAG22 protein



/DB_XREF = gi: 13236500 /UG = Hs.283080 NAG22 protein /FL = gb: AF247820.3



gb: NM_018495.3


205595_at
desmoglein 3 (pemphigus vulgaris antigen)


205608_s_at
angiopoietin 1


205636_at
SH3-domain GRB2-like 3 [BLAST]


205729_at
oncostatin M receptor


205752_s_at
glutathione S-transferase M5


205879_x_at
ret proto-oncogene (multiple endocrine neoplasia and



medullary thyroid carcinoma 1, Hirschsprung disease)


206096_at
zinc finger protein 35 (clone HF.10)


206212_at
carboxypeptidase A2 (pancreatic)


206263_at
flavin containing monooxygenase 4


206291_at
neurotensin


206388_at
phosphodiesterase 3A, cGMP-inhibited


206389_s_at
phosphodiesterase 3A, cGMP-inhibited


206456_at
gamma-aminobutyric acid (GABA) A receptor, alpha 5


206586_at
cannabinoid receptor 2 (macrophage)


206766_at
integrin, alpha 10


206825_at
oxytocin receptor


206910_x_at
H factor (complement)-like 3


206936_x_at
chromosome 20 open reading frame 110


207041_at
mannan-binding lectin serine protease 2


207064_s_at
amine oxidase, copper containing 2 (retina-specific)


207131_x_at
gamma-glutamyltransferase 1


207347_at
excision repair cross-complementing rodent repair



deficiency, complementation group 6


207408_at
organic cationic transporter-like 4


207608_x_at
cytochrome P450, subfamily I (aromatic compound-



inducible), polypeptide 2


207732_s_at
discs, large (Drosophila) homolog 3 (neuroendocrine-dlg)


207755_at
chromosome 20 open reading frame 48


207908_at
keratin 2A (epidermal ichthyosis bullosa of Siemens)


207936_x_at
ret finger protein-like 3


207938_at
protease inhibitor 15


207969_x_at
acrosomal vesicle protein 1 [BLAST]


208124_s_at
sema domain, immunoglobulin domain (Ig), transmembrane



domain (TM) and short cytoplasmic domain, (semaphorin) 4F


208138_at
gastrin


208185_x_at
Consensus includes gb: NM_016415.1 /DEF = Homo sapiens clone



FLB3816 (LOC51216), mRNA. /FEA = mRNA /GEN = LOC51216 /PROD = clone FLB3816



/DB_XREF = gi: 10047109 /UG = Hs.277887 clone FLB3816 /FL = gb: NM_016415.1



. . .


208351_s_at
mitogen-activated protein kinase 1


208360_s_at
gb: NM_015870.1 /DEF = Homo sapiens endogenous retrovirus H



D1 leader regionintegrase-derived ORF1, ORF2, and putative envelope



protein (HSU88895), mRNA. /FEA = mRNA /GEN = HSU88895 /PROD = endogenous



re . . .


208382_s_at
DMC1 dosage suppressor of mck1 homolog, meiosis-specific



homologous recombination (yeast)


208447_s_at
phosphoribosyl pyrophosphate synthetase 1


208486_at
cytochrome P450, subfamily IVA, polypeptide 11 [BLAST]


208679_s_at
actin related protein 2/3 complex, subunit 2 (34 kD)


208730_x_at
RAB2, member RAS oncogene family


208763_s_at
delta sleep inducing peptide, immunoreactor


208860_s_at
alpha thalassemia/mental retardation syndrome X-linked



(RAD54 homolog, S. cerevisiae)


208868_s_at
GABA(A) receptor-associated protein like 1


208869_s_at
GABA(A) receptor-associated protein like 1


208937_s_at
inhibitor of DNA binding 1, dominant negative helix-loop-



helix protein


209312_x_at
gb: U65585.1 /DEF = Homo sapiens MHC class II antigen (HLA-



DRB1) mRNA, HLA-DRB1*PBL allele, complete cds. /FEA = mRNA /GEN = HLA-



DRB1 /PROD = MHC class II antigen /DB_XREF = gi: 5478215 /UG = Hs.180255



major . . .


209436_at
spondin 1, (f-spondin) extracellular matrix protein


209535_s_at
LIM and SH3 protein 1


209701_at
desmin [BLAST]


209703_x_at
component of oligomeric golgi complex 4


209790_s_at
caspase 6, apoptosis-related cysteine protease [BLAST]


209882_at
Ric-like, expressed in many tissues (Drosophila)


210048_at
N-ethylmaleimide-sensitive factor attachment protein,



gamma


210191_s_at
putative homeodomain transcription factor 1


210226_at
nuclear receptor subfamily 4, group A, member 1


210412_at
glutamate receptor, ionotropic, N-methyl D-aspartate 2B


210639_s_at
APG5 autophagy 5-like (S. cerevisiae)


210739_x_at
solute carrier family 4, sodium bicarbonate



cotransporter, member 4


210757_x_at
disabled homolog 2, mitogen-responsive phosphoprotein



(Drosophila)


210796_x_at
sialic acid binding Ig-like lectin 6


210830_s_at
paraoxonase 2


210836_x_at
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3



dunce homolog, Drosophila)


210837_s_at
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3



dunce homolog, Drosophila)


210912_x_at
glutathione S-transferase M4


210923_at
chromosome 20 open reading frame 82


210944_s_at
calpain 3, (p94)


210962_s_at
A kinase (PRKA) anchor protein (yotiao) 9


211014_s_at
promyelocytic leukemia


211026_s_at
monoglyceride lipase [BLAST]


211040_x_at
gb: BC006325.1 /DEF = Homo sapiens, G-2 and S-phase



expressed 1, clone MGC: 12560, mRNA, complete cds. /FEA = mRNA /PROD = G-



2 and S-phase expressed 1 /DB_XREF = gi: 13623450 /FL = gb: BC006325.1


211071_s_at
chromosome 12 open reading frame 8 [BLAST]


211074_at
gb: AF000381.1 /DEF = Homo sapiens non-functional folate



binding protein mRNA, complete cds. /FEA = mRNA /PROD = non-functional



folate binding protein /DB_XREF = gi: 2565195 /FL = gb: AF000381.1


211096_at
pre-B-cell leukemia transcription factor 2


211113_s_at
ATP-binding cassette, sub-family G (WHITE), member 1


211139_s_at
NGFI-A binding protein 1 (EGR1 binding protein 1)


211277_x_at
amyloid beta (A4) precursor protein (protease nexin-II,



Alzheimer disease)


211316_x_at
CASP8 and FADD-like apoptosis regulator


211328_x_at
hemochromatosis


211364_at
methylthioadenosine phosphorylase


211416_x_at
gamma-glutamyltransferase 1


211460_at
testis-specific transcript, Y-linked 9


211464_x_at
caspase 6, apoptosis-related cysteine protease


211504_x_at
Rho-associated, coiled-coil containing protein kinase 2


211574_s_at
membrane cofactor protein (CD46, trophoblast-lymphocyte



cross-reactive antigen)


211657_at
carcinoembryonic antigen-related cell adhesion molecule 6



(non-specific cross reacting antigen) [BLAST]


211685_s_at
neurocalcin delta [BLAST]


211713_x_at
histone deacetylase 4 [BLAST]


211769_x_at
tumor differentially expressed 1 [BLAST]


211781_x_at
gb: BC006164.1 /DEF = Homo sapiens, clone MGC: 13219, mRNA,



complete cds. /FEA = mRNA /PROD = Unknown (protein for MGC: 13219)



/DB_XREF = gi: 13544062 /FL = gb: BC006164.1


211801_x_at
hypoxia-inducible factor 1, alpha subunit inhibitor


211810_s_at
galactosylceramidase (Krabbe disease)


211814_s_at
cyclin E2


211918_x_at
placenta-specific 3 [BLAST]


212196_at
tumor necrosis factor receptor superfamily, member 19-



like [BLAST]


212233_at
chromosome 1 open reading frame 2


212514_x_at
Consensus includes gb: R60068 /FEA = EST /DB_XREF = gi: 830763



/DB_XREF = est: yh12h07.s1 /CLONE = IMAGE: 43138 /UG = Hs.147916 DEADH (Asp-



Glu-Ala-AspHis) box polypeptide 3


212736_at
Consensus includes gb: BE299456 /FEA = EST



/DB_XREF = gi: 9183204 /DB_XREF = est: 600944717T1 /CLONE = IMAGE: 2960548



/UG = Hs.6349 Human Chromosome 16 BAC clone CIT987SK-A-362G6


212876_at
UDP-Gal: betaGlcNAc beta 1,4-galactosyltransferase,



polypeptide 4


212884_x_at
apolipoprotein E [BLAST]


213139_at
snail homolog 2 (Drosophila)


213193_x_at
T cell receptor beta locus


213297_at
nucleolar protein family A, member 2 (H/ACA small



nucleolar RNPs)


213307_at
Consensus includes gb: AF131790.1 /DEF = Homo sapiens clone



24903 mRNA sequence. /FEA = mRNA /DB_XREF = gi: 4406618 /UG = Hs.12696



cortactin SH3 domain-binding protein


213406_at
golgi associated, gamma adaptin ear containing, ARF



binding protein 1


213486_at
retinoic acid induced 17 [BLAST]


213816_s_at
met proto-oncogene (hepatocyte growth factor receptor)


213936_x_at
surfactant, pulmonary-associated protein B


214007_s_at
protein tyrosine kinase 9 [BLAST]


214336_s_at
coatomer protein complex, subunit alpha


214421_x_at
cytochrome P450, subfamily IIC (mephenytoin 4-



hydroxylase), polypeptide 9 [BLAST]


214656_x_at
myosin IC


214698_at
Consensus includes gb: AW190873 /FFA = EST



/DB_XREF = gi: 6465353 /DB_XREF = est: x166a01.x1 /CLONE = IMAGE: 2679624



/UG = Hs.145078 regulator of differentiation (in S. pombe) 1


214720_x_at
Consensus includes gb: BF981643 /FEA = EST



/DB_XREF = gi: 12384455 /DB_XREF = est: 602305961F1 /CLONE = IMAGE: 4397295



/UG = Hs.79844 DKFZP564M1416 protein


214849_at
Consensus includes gb: AW500220 /FEA = EST



/DB_XREF = gi: 7112628 /DB_XREF = est: UI-HF-BN0-akd-c-02-0-UI.r1



/CLONE = IMAGE: 3076610 /UG = Hs.332496 Human DNA sequence from clone



108K11 on chromosome 6p21 Cont . . .


214906_x_at
ATPase, H+ transporting, lysosomal 31 kD, V1 subunit E



isoform 2


214923_at
Consensus includes gb: AK001155.1 /DEF = Homo sapiens cDNA



FLJ10293 fis, clone NT2RM1000280, highly similar to VACUOLAR ATP



SYNTHASE SUBUNIT D (EC 3.6.1.34). /FEA = mRNA /DB_XREF = gi: 7022230



/UG = Hs.30 . . .


214933_at
calcium channel, voltage-dependent, P/Q type, alpha 1A



subunit


214951_at
UDP-N-acetyl-alpha-D-galactosamine: (N-acetylneuraminyl)-



galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-



T)


214953_s_at
amyloid beta (A4) precursor protein (protease nexin-II,



Alzheimer disease)


215032_at
nudix (nucleoside diphosphate linked moiety X)-type motif



11


215178_x_at
N-acylsphingosine amidohydrolase (acid ceramidase)-like


215236_s_at
phosphatidylinositol binding clathrin assembly protein


215366_at
sorting nexin 6


215439_x_at
F-box and leucine-rich repeat protein 11


215479_at
immunoglobulin superfamily, member 9 [BLAST]


215588_x_at
Consensus includes gb: AK024958.1 /DEF = Homo sapiens cDNA:



FLJ21305 fis, clone COL02124. /FEA = mRNA /DB_XREF = gi: 10437382



/UG = Hs.287658 Homo sapiens cDNA: FLJ21305 fis, clone COL02124


215609_at
Consensus includes gb: AK023895.1 /DEF = Homo sapiens cDNA



FLJ13833 fis, clone THYRO1000676. /FEA = mRNA /DB_XREF = gi: 10435969



/UG = Hs.296745 Homo sapiens cDNA FLJ13833 fis, clone THYRO1000676


215758_x_at
zinc finger protein 253


215766_at
Consensus includes gb: AL096729.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp434D044 (from clone DKFZp434D044). /FEA = mRNA



/DB_XREF = gi: 5419863 /UG = Hs.146581 Homo sapiens mRNA; cDNA



DKFZp434D044 (from clone . . .


215825_at
Consensus includes gb: AF070579.1 /DEF = Homo sapiens clone



24487 mRNA sequence. /FEA = mRNA /DB_XREF = gi: 3387951 /UG = Hs.283819 Homo



sapiens clone 24487 mRNA sequence


215856_at
Consensus includes gb: AK025833.1 /DEF = Homo sapiens cDNA:



FLJ22180 fis, clone HRC00936. /FEA = mRNA /DB_XREF = gi: 10438467



/UG = Hs.287692 Homo sapiens cDNA: FLJ22180 fis, clone HRC00936


215910_s_at
carbohydrate (chondroitin) synthase 1


216061_x_at
platelet-derived growth factor beta polypeptide (simian



sarcoma viral (v-sis) oncogene homolog)


216159_s_at
prostate tumor over expressed gene 1


216196_at
chromosome 20 open reading frame 136 [BLAST]


216220_s_at
adenosine A1 receptor


216292_at
Consensus includes gb: AK024455.1 /DEF = Homo sapiens mRNA



for FLJ00047 protein, partial cds. /FEA = mRNA /GEN = FLJ00047



/PROD = FLJ00047 protein /DB_XREF = gi: 10440423 /UG = Hs.287753 Homo



sapiens mRNA for . . .


216294_s_at
ubiquitin specific protease 24


216374_at
Consensus includes gb: AC006986 /DEF = Homo sapiens BAC



clone RP11-155J5 from Y /FEA = CDS /DB_XREF = gi: 4753246 /UG = Hs.283908



Homo sapiens BAC clone RP11-155J5 from Y


216661_x_at
cytochrome P450, subfamily IIC (mephenytoin 4-



hydroxylase), polypeptide 9


216735_x_at
prostate tumor over expressed gene 1 [BLAST]


216745_x_at
Consensus includes gb: AK024606.1 /DEF = Homo sapiens cDNA:



FLJ20953 fis, clone ADSE01979. /FEA = mRNA /DB_XREF = gi: 10436920



/UG = Hs.306697 Homo sapiens cDNA: FLJ20953 fis, clone ADSE01979


216791_at
lysyl oxidase-like 4 [BLAST]


216859_x_at
Consensus includes gb: AL080112.1 /DEF = Homo sapiens mRNA;



cDNA DKFZp586H0722 (from clone DKFZp586H0722). /FEA = mRNA



/DB_XREF = gi: 5262539 /UG = Hs.332731 Homo sapiens mRNA; cDNA



DKFZp586H0722 (from clo . . .


216873_s_at
ATPase, Class I, type 8B, member 2


216936_at
Consensus includes gb: X81637.1 /DEF = H. sapiens clathrin



light chain b gene. /FEA = mRNA /DB_XREF = gi: 963046 /UG = Hs.73919



clathrin, light polypeptide (Lcb)


216993_s_at
Consensus includes gb: U32169 /DEF = Human pro-a2 chain of



collagen type XI (COL11A2) gene, complete cds /FEA = mRNA_3



/DB_XREF = gi: 1000744 /UG = Hs.121509 collagen, type XI, alpha 2


217020_at
retinoic acid receptor, beta


217117_x_at
Consensus includes gb: AF007194.1 /DEF = Homo sapiens mucin



(MUC3) mRNA, partial cds. /FEA = mRNA /GEN = MUC3 /PROD = mucin



/DB_XREF = gi: 2853300 /UG = Hs.129782 mucin 3A, intestinal


217189_s_at
chromosome 1 open reading frame 16


217269_s_at
protease, serine, 7 (enterokinase)


217315_s_at
kallikrein 13


217377_x_at
ets variant gene 6 (TEL oncogene)


217457_s_at
RAP1, GTP-GDP dissociation stimulator 1


217465_at
NCK-associated protein 1 [BLAST]


217480_x_at
G protein-coupled receptor 2


217703_x_at
Consensus includes gb: AA401963 /FEA = EST



/DB_XREF = gi: 2055965 /DB_XREF = est: zu53c08.s1 /CLONE = IMAGE: 741710



/UG = Hs.194107 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ



SEQUENCE CONTAMINATIO . . .


217787_s_at
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-



acetylgalactosaminyltransferase 2 (GalNAc-T2)


217859_s_at
synaptojanin 2 binding protein


217862_at
protein inhibitor of activated STAT, 1


217878_s_at
Consensus includes gb: AI203880 /FEA = EST



/DB_XREF = gi: 3756486 /DB_XREF = est: qf77g07.x1 /CLONE = IMAGE: 1756092



/UG = Hs.172405 cell division cycle 27 /FL = gb: NM_001256.1


218211_s_at
transgene insertion 202, William Muller


218554_s_at
solute carrier family 22 (organic anion/cation



transporter), member 11


218949_s_at
chromosome 15 open reading frame 12


219014_at
toll-like receptor 8


219032_x_at
opsin 3 (encephalopsin, panopsin)


219183_s_at
pleckstrin homology, Sec7 and coiled/coil domains 4


219194_at
sema domain, immunoglobulin domain (Ig), transmembrane



domain (TM) and short cytoplasmic domain, (semaphorin) 4G


219221_at
engulfment and cell motility 3 (ced-12 homolog, C. elegans)


219228_at
chromosome Y open reading frame 14


219398_at
zinc finger protein 338


219472_at
matrix metalloproteinase 28


219677_at
UDP-glucuronate decarboxylase 1


219679_s_at
gb: NM_018604.1 /DEF = Homo sapiens hypothetical protein



PRO1741 (PRO1741), mRNA. /FEA = mRNA /GEN = PRO1741 /PROD = hypothetical



protein PRO1741 /DB_XREF = gi: 8924074 /UG = Hs.306067 hypothetical



protein PRO . . .


219702_at
placenta-specific 1


219757_s_at
chromosome 20 open reading frame 21


219860_at
chromosome 6 open reading frame 20


219910_at
coronin, actin binding protein, 1A


219977_at
aryl hydrocarbon receptor interacting protein-like 1


220115_s_at
gb: NM_006727.1 /DEF = Homo sapiens cadherin 10, type 2 (T2-



cadherin) (CDH10), mRNA. /FEA = mRNA /GEN = CDH10 /PROD = cadherin 10, type



2 (T2-cadherin) /DB_XREF = gi: 5802995 /UG = Hs.92489 cadherin 10, type 2 . . .


220287_at
a disintegrin-like and metalloprotease (reprolysin type)



with thrombospondin type 1 motif, 9


220398_at
matrix metalloproteinase 28


220446_s_at
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4


220560_at
chromosome 11 open reading frame 21


220574_at
chromosome 20 open reading frame 48


220725_x_at
UDP-glucuronate decarboxylase 1


220776_at
potassium inwardly-rectifying channel, subfamily J,



member 14


220800_s_at
tropomodulin 3 (ubiquitous)


220833_at
myosin XVA


220838_at
chromosome 20 open reading frame 21


220853_at
Kruppel-like factor 15


220944_at
RAB25, member RAS oncogene family


221078_s_at
LUC7-like (S. cerevisiae)


221107_at
cholinergic receptor, nicotinic, alpha polypeptide 9


221220_s_at
hypoxia-inducible factor 1, alpha subunit inhibitor


221460_at
olfactory receptor, family 2, subfamily C, member 1


221473_x_at
tumor differentially expressed 1


221541_at
espin


221695_s_at
mitogen-activated protein kinase kinase kinase 2 [BLAST]


221717_at
G protein-coupled receptor 52


221757_at
chromosome 20 open reading frame 54


221832_s_at
cysteine and tyrosine-rich 1 [BLAST]


221917_s_at
G-rich RNA sequence binding factor 1


221997_s_at
Ca<2+>dependent activator protein for secretion [BLAST]


222368_at
Consensus includes gb: AW972351 /FEA = EST



/DB_XREF = gi: 8162197 /DB_XREF = est: EST384442 /UG = Hs.293451 ESTs


222370_x_at
RAS, guanyl releasing protein 4

## Claims

1. A method of treating a subject suffering from a cancer selected from the group consisting of breast cancer and liver cancer, the method comprising:
(i) preparing a pharmaceutical composition by a method comprising
(a) comminuting rhizomes of Fagopyrum dibotrys;
(b) extracting the comminuted material with a solvent comprising a C1-C4 alcohol to produce a liquid extract; and
(c) removing solvent from the liquid extract to produce a dried or concentrated material; and optionally
(d) fractionating the dried or concentrated material; and

(ii) administering the pharmaceutical composition to the subject.

2. A method according to claim 1 wherein the solvent comprises ethanol.

3. A method according to claim 1 wherein an excipient is added to the liquid extract and step (c) comprises drying under reduced pressure to produce a dry material.

4. The method according to claim 1 wherein the cancer is breast cancer.

5. The method according to claim 1 wherein the cancer is liver cancer.