Exhibit 10.10

                                 PROMISSORY NOTE

                           NANOBAC PHARMACEUTICALS INC

$2,233,668                                                     December 31, 2003
5%                                                             Tampa, Florida

1.   Promise to Pay. NANOBAC PHARMACEUTICALS INC a Florida Corporation
     ("Borrower"), for value received promises to pay to the order of Escape
     Velocity, Inc. ("Lender"), the principal amount of TWO MILLION TWO HUNDRED
     THRITY-THREE THOUSAND SIX HUNDRED SIXTY-EIGHT U.S. DOLLARS (U.S.
     $2,233,668) on demand.

2.   Addiitons to Principal. From time to time, Borrower may advance additional
     funds to Lendor. Such additional advances shall be covered by the terms of
     this note.

3.   Interest. Interest shall be payable at five percent (5%) per annum
     compounded annually and added to the principal balance of the note.

4.   Default; Remedies; Payment of Costs. The dissolution, insolvency,
     appointment of a custodian, trustee, or receiver for the Borrower, the
     Borrower files (or any creditor files against the Borrower) a petition
     seeking relief under any bankruptcy, insolvency, reorganization, or other
     debtor relief law, or the Borrower dies shall be considered a Default.

     On the occurrence of a "Default" and at any time thereafter Lender, at its
     option and as often as it desires, may declare the full principal amount of
     this Note to be immediately due and payable without demand, notice, or
     presentment.

     Borrower shall pay all costs associated with Lendor's collection of this in
     case of Default or non-payment upon demand.

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5.   Waiver and Consents. Borrower and every person liable at any time for
     payment of this Note waives presentment, protest, notice of protest, and
     notice of dishonor. Borrower expressly consents to all extensions and
     renewals of this Note (as a whole or in part) and all delays in time of
     payment or other performance under this Note that the holder of this Note
     grants at any time and from time to time, without limitation and without
     any notice to or further consent of Borrower. Borrower agrees that its
     obligation under the Note are independent of the obligations of any other
     person or entity that now or later is obligated to pay this Note. Borrower
     also agrees that Lender may release any security for or other obligor of
     this Note or waive, extend, alter, amend, or modify the Note or otherwise
     take any action that varies the risk of Borrower without releasing or
     discharging Borrower form its obligation to repay this Note.

6.   Venue and Waiver of Jury Trial. Borrower further agrees that venue for each
     action, suit, or other legal proceeding arising under or relating to this
     Note or any agreement securing or related to this Note shall be in Tampa,
     Florida. Borrower and Lender knowingly, voluntarily, and intentionally
     waive all rights to a jury trial in any lawsuit, proceeding, counterclaim,
     or other litigation arising under or relating to this Note or any agreement
     securing or relating to this Note. Borrower and Lender have fully discussed
     this provision and agree that this waiver is subject to no exception and
     was a material inducement for Lender to make the loan to Borrower that is
     evidenced by this Note.

7.   Miscellaneous. The headings preceding the text of the sections of this Note
     have been inserted solely for convenience of reference and do not limit or
     affect the meaning, interpretation, or effect of this Note. The validity,
     construction, interpretation, and enforceability of this Note are governed
     by the laws of the State of Florida, excluding its laws relating to the
     resolution of conflicts of laws of different jurisdictions.

EXECUTED: December 31, 2003, in Tampa, Florida



                                          By: /s/ Alexander H. Edwards III
                                          --------------------------------
                                          Alexander H. Edwards III
                                          For Nanobac Pharmaceuticals Inc


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