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                                                                   Exhibit 10.37

         SECURITIES PURCHASE AGREEMENT, dated as of March 16, 2004 (this
"AGREEMENT"), between MICROISLET, INC., a Nevada corporation with principal
executive offices at 6370 Nancy Ridge Drive, Suite 112, San Diego, California
92121 (the "COMPANY"), and the purchaser identified on the signature page hereto
(the "PURCHASER").

                                  INTRODUCTION

         Subject to the terms and conditions of this Agreement, the Company may
issue and sell to the Purchaser and the Purchaser shall purchase from the
Company the following: (i) a minimum of the total number of shares (the
"SHARES") of common stock of the Company (the "COMMON STOCK") shown in Schedule
1.01(a); (ii) warrants (the "$1.00 WARRANTS") exercisable for an aggregate of
the number of shares of Common Stock shown on Schedule 1.01(a) at the exercise
price of $1.00 per share, in the form attached hereto as Exhibit A; and (iii)
warrants (the "$1.30 WARRANTS", and, together with the $1.00 Warrants, the
"WARRANTS") exercisable for an aggregate of the number of shares of Common Stock
shown on Schedule 1.01(a) at the exercise price of $1.30 per share, in the form
attached hereto as Exhibit A(1). The Warrants, together with this Agreement, are
hereinafter referred to as the "TRANSACTION AGREEMENTS." The $1.00 Warrants
shall be exercisable until the fifth anniversary of the execution and delivery
of this Agreement, and the $1.30 Warrants shall be exercisable until the fifth
anniversary of the Second Closing. The term "SECURITIES" as used herein shall
refer to (x) the Shares, the Warrants and the shares issuable upon exercise of
the Warrants (the "WARRANT SHARES").

         NOW THEREFORE, in consideration of the mutual covenants contained in
this Agreement, the Company and the Purchaser hereby agree as follows:

                                    ARTICLE I

                            ACQUISITION OF SECURITIES

         SECTION 1.01 THE AGREEMENT.

         (a) Subject to the terms and conditions of this Agreement, the Company
shall issue and sell to the Purchaser and the Purchaser shall purchase from the
Company the Shares in two installments as follows: (i) following the execution
and delivery hereof by the parties hereto, the Purchaser shall purchase the
number of Shares included in the First Tranche as set forth in Schedule 1.01(a),
in the manner provided in Section 1.02(a) (the "FIRST TRANCHE"); and (ii)
following the effectiveness of the Registration Statement (as defined in Section
3.01 below) (the "EFFECTIVE DATE"), the Purchaser shall purchase the number of
Shares included in the Second Tranche as set forth in Schedule 1.01(a) (the
"SECOND TRANCHE"), subject to receipt of an Election Notice (as defined below)
from the Company(2). The purchase price per share (in either case, the "TRANCHE
PURCHASE PRICE") for the Shares sold in the First Tranche and the Second Tranche
shall be as set forth in Schedule 1.01(a).

_____________

(1) If the $1.30 warrants are stated to be for zero shares, no $1.30 warrants
will be issued, and all references in this Agreement to the $1.30 warrants
should be disregarded.

(2) If the number of Shares to be purchased in the Second Tranche is stated to
be zero, then there shall be no Second Closing (as defined in Section 1.02(a)),
and neither party shall have any obligations with respect to the Second Tranche
or the Second Closing.


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         (b) To effect its election to sell Shares in the Second Tranche, the
Company shall deliver to Purchaser written notice within five Business Days
after the effectiveness of the Registration Statement (an "ELECTION NOTICE")
specifying that the Company wishes to sell such Shares to the Purchaser. The
Election Notice shall specify that the election is being made and the date on
which the closing of the Second Tranche shall occur; provided, such date shall
be a Business Day (as hereinafter defined) and shall not be earlier than five
Business Days or later than ten Business Days after the date such Election
Notice is given to the Purchaser. In no event will the closing date of the
Second Tranche be set for a date after December 31, 2004. An Election Notice
shall be irrevocable. For purposes hereof, the term "BUSINESS DAY" shall mean
any day which is not (i) a Saturday or a Sunday or (ii) a day on which banking
institutions are generally authorized or obligated to close in the City of Los
Angeles, California. Subject to the foregoing and to the applicable conditions
in Sections 4.01, 4.02 and 4.03 hereof, the Purchaser shall be obligated to
purchase the Shares in the Second Tranche.

         (c) The Company shall not effect the sale of shares in the Second
Tranche, and the Purchaser shall not have the right to purchase Shares in the
Second Tranche, to the extent that after giving effect to such purchase the
Purchaser together with its affiliates would beneficially own in excess of 9.8%
of the outstanding shares of the Common Stock following such purchase. For
purposes hereof, the number of shares of Common Stock beneficially owned by the
Purchaser and its affiliates or acquired by the Purchaser and its affiliates, as
the case may be, shall include the number of Shares issuable in connection with
the Second Tranche. If the 9.8% limitation is reached, this shall not affect or
limit the Purchaser's obligation to purchase the Shares in the Second Tranche as
otherwise provided in this Agreement. Specifically, even though the Purchaser
may not receive additional shares of Common Stock in the event that the 9.8%
limitation is ever reached, the Purchaser is still obligated to pay to the
Company the Purchase Price as otherwise obligated under this Agreement. Under
such circumstances, the Purchaser would have the right to have issued the
additional shares of Common Stock in the future only at such time as its
ownership decreased so as to permit issuance of Shares without violation of this
Section 1.01(c). The number of outstanding shares of Common Stock shall be
determined after giving effect to any purchases under this Agreement by the
Purchaser since the date as of which such number of outstanding shares of Common
Stock was reported. Except as otherwise set forth herein, for purposes of this
Section 1.01(c), beneficial ownership shall be determined in accordance with
Section 13(d) of the Securities Exchange Act of 1934, as amended (the "EXCHANGE
ACT").

         (d) (i) Upon the First Closing (as defined below), the Purchaser shall
be granted the $1.00 Warrants.

         (ii) In addition, upon the Second Closing (as defined below) the
Purchaser shall be granted the $1.30 Warrants.

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                  (iii) If at any time or from time to time prior to the
Effective Date, the Company sells any Common Stock or any indebtedness, bonds,
debentures, notes, preferred stock or similar equity securities which are
convertible into or exercisable for Common Stock at a price (the "SUBSEQUENT
PRICE") less than $1.30, the Company shall issue to the Purchaser within five
(5) Business Days following the such sale the number of additional shares of
Common Stock determined according to the following formula:

                  (($1.30 - Subsequent Price) x the number of Shares purchased
in the First Tranche) / Subsequent
Price

Notwithstanding anything to the contrary herein, the provisions of this Section
1.01(d)(iii) shall not apply to (i) securities issued to employees, consultants,
officers or directors of the Company pursuant to any stock option, stock
purchase or stock bonus plan, agreement or arrangement approved by the Board of
Directors; (ii) securities issued pursuant to the acquisition of another
business entity or business segment of any such entity by the Company by merger,
purchase of substantially all of the assets or other reorganization whereby the
Company will own more than fifty (50%) of the voting power of such business
segment of any such entity; (iii) securities issued to vendors or customers or
to other persons in similar commercial situations with the Company if such
issuance is approved by the Board of Directors; (iv) securities issued in
corporate partnering transactions on terms approved by the Board of Directors;
(v) the Warrants, or any similar warrants issued by the Company in
contemporaneous financing transactions as described in Section 2.02(g), or any
securities issued upon exercise thereof; (vi) securities issued in accordance
with the terms of any of the Company's warrants outstanding on the date hereof;
or (vii) borrowings, direct or indirect, from financial institutions regularly
engaged in the business of lending money, whether or not presently authorized
with an equity component which is not a major component of such borrowing.


         SECTION 1.02 CLOSING PROCEDURES; THE CLOSINGS.

         (a) Subject to the satisfaction or waiver of the conditions precedent
set forth in Sections 4.01 and 4.02 hereof, the closing of the sale and purchase
of the Securities to be delivered in the First Tranche shall take place
immediately following the execution and delivery of this Agreement, or as soon
thereafter as practicable (the "FIRST CLOSING"); and subject to the satisfaction
or waiver of the conditions precedent set forth in Sections 4.01, 4.02 and 4.03
hereof and the procedures set forth herein, the closing of the sale and purchase
of the Securities to be delivered in the Second Tranche shall take place on the
date specified in the Election Notice (the "SECOND CLOSING") (the "FIRST
CLOSING" and the "SECOND CLOSING," each a "CLOSING"). Unless otherwise agreed by
the Company and the Purchaser, each Closing shall occur at the offices of
Procopio, Cory, Hargreaves & Savitch LLP, counsel to the Company.

         (b) At each Closing, (i) each of the Company and the Purchaser shall
deliver to the other, as applicable, any documents required to be delivered by
Article IV hereof which have not been delivered prior to such Closing, (ii) the
Purchaser shall pay the applicable Tranche Purchase Price for the Shares being
purchased at the Closing by wire transfer of immediately available funds to an
account designated in writing by the Company at or prior to the Closing, and
(iii) the Company shall deliver to the Purchaser one or more stock certificates,
determined in accordance with the instructions of the Purchaser, representing
the Shares being purchased or shall cause the Shares being purchased to be
electronically transferred to the Purchaser.


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         SECTION 1.03 ILLIQUIDITY OF INVESTMENT; SECURITIES LAWS.

         (a) The offering and proposed sale of Shares and the Warrants herein
have not been registered or qualified under the Securities Act of 1933, as
amended (the "SECURITIES ACT") nor under the securities laws of California or
any other state. This offering has not been reviewed by the United States
Securities and Exchange Commission (the "COMMISSION") nor has the Commission or
any state securities commission or regulatory authority approved, passed upon or
endorsed the merits of this offering. The offering and proposed sale of the
Shares and the Warrants herein is being made in reliance upon certain securities
exemptions, including (i) Rule 506 of Regulation D promulgated under the
Securities Act, and (ii) the exemption set forth in Section 25102(f) of the
California Corporate Securities Law of 1968, as amended, and the regulations
promulgated thereunder.

         (b) It is believed that the offering and proposed sale of the Shares
and the Warrants currently qualifies and will continue to qualify under each
such claimed exemption. Because the availability of these exemptions is based
upon subjective factors, however, and because the criteria for exemption are
subject to interpretation by state or federal regulatory agencies and courts,
there is no assurance that such exemptions will be available. If and to the
extent that suits for rescission are brought for failure to register this
offering or for acts or omissions constituting offenses under the Securities Act
or the securities laws of any state, the capital and financial condition of the
Company could be materially adversely affected. In addition, the Company could
be adversely affected by the need to defend any such private or governmental
action even where the Company ultimately is exonerated.

                                   ARTICLE II

                          REPRESENATIONS AND WARRANTIES

         SECTION 2.01 REPRESENTATIONS AND WARRANTIES OF THE COMPANY. The Company
hereby represents and warrants to the Purchaser, subject to such exceptions as
are listed in the disclosure letter to be delivered to Purchaser on or prior to
the First Closing, or as otherwise disclosed in the Company's SEC Documents (as
defined below), as follows:

         (a) The Common Stock has been registered under Section 12(g) of the
Exchange Act and the Company is subject to the periodic reporting requirements
of Section 13 of the Exchange Act. The Company has heretofore provided to the
Purchaser true, complete, and correct copies of all forms, reports, schedules,
statements, and other documents required to be filed by it under the Exchange
Act since at least April 24, 2002 as such documents have been amended since the
time of the filing thereof (collectively, the "SEC DOCUMENTS"). The SEC
Documents, including, without limitation, any financial statements and schedules
included therein, at the time filed or, if subsequently amended, as so amended,
(i) did not contain any untrue statement of a material fact required to be
stated therein or necessary in order to make the statements therein not
misleading and (ii) complied in all respects with the applicable requirements of
the Exchange Act and the applicable rules and regulations thereunder.


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         (b) At the date hereof and at each Closing:

                  (i) the Common Stock is and shall be traded and quoted in the
over-the-counter Bulletin Board market (the "OTCBB");

                  (ii) the Company has and shall have performed or satisfied all
of its undertakings to, and its obligations and requirements with, the
Commission; and

                  (iii) the Company has not, and shall not have taken any action
that would preclude, or otherwise jeopardize, the inclusion of the Common Stock
for quotation on the OTCBB.

         (c) MicroIslet of Delaware, Inc., a Delaware corporation
("SUBSIDIARY"), is the sole subsidiary of the Company. Other than Subsidiary,
the Company has no subsidiaries or affiliated corporations and does not own any
interest in any other enterprise (whether or not such enterprise is a
corporation). Each of the Company and Subsidiary has been duly organized and is
validly existing as a corporation in good standing under the laws of the
respective jurisdiction of its incorporation with full power and authority
(corporate and other) to own, lease and operate its respective properties and
conduct its respective business as described in the SEC Documents; each of the
Company and Subsidiary is duly qualified to do business as a foreign corporation
and is in good standing in each jurisdiction in which the ownership or leasing
of its respective properties or the conduct of its respective business requires
such qualification, except where the failure to be so qualified or be in good
standing would not have a material adverse effect on the business, prospects,
condition (financial or otherwise), and results of operations of the Company and
Subsidiary taken as a whole; no proceeding has been instituted in any such
jurisdiction, revoking, limiting or curtailing, or seeking to revoke, limit or
curtail, such power and authority or qualification; each of the Company and
Subsidiary is in possession of, and operating in compliance with, all
authorizations, licenses, certificates, consents, orders and permits from state,
federal, foreign and other regulatory authorities that are material to the
conduct of its business, all of which are valid and in full force and effect;
neither the Company nor Subsidiary is in violation of its charter or bylaws or
in default in the performance or observance of any obligation, agreement,
covenant or condition contained in any material bond, debenture, note or other
evidence of indebtedness, or in any material lease, contract, indenture,
mortgage, deed of trust, loan agreement, joint venture or other agreement or
instrument to which it is a party or by which it or its respective properties or
assets may be bound, which violation or default would have a material adverse
effect on the business, prospects, financial condition or results of operations
of the Company and Subsidiary taken as a whole; and neither the Company nor
Subsidiary is in violation of any law, order, rule, regulation, writ,
injunction, judgment or decree of any court, government or governmental agency
or body, domestic or foreign, having jurisdiction over the Company or Subsidiary
or over its respective properties or assets, which violation would have a
material adverse effect on the business, prospects, financial condition or
results of operations of the Company and Subsidiary taken as a whole. The SEC
Documents accurately describe any corporation, association or other entity owned
or controlled, directly or indirectly, by the Company or Subsidiary.


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         (d) The Company has full legal right, power and authority to enter into
each of the Transaction Agreements and to perform the transactions contemplated
hereby and thereby. Each of the Transaction Agreements has been duly authorized,
executed and delivered by the Company and is a valid and binding agreement on
the part of the Company, enforceable in accordance with its respective terms
(except as such enforceability may be subject to the laws of general application
relating to bankruptcy, insolvency and the relief of debtors and rules of law
governing specific performance, injunctive relief or other equitable remedies);
the performance of each of the Transaction Agreements and the consummation of
the transactions herein or therein contemplated will not result in a breach or
violation of any of the terms and provisions of, or constitute a default under,
(i) any bond, debenture, note or other evidence of indebtedness, or under any
lease, contract, indenture, mortgage, deed of trust, loan agreement, joint
venture or other agreement or instrument to which the Company or Subsidiary is a
party or by which its respective properties or assets may be bound, (ii) the
charter or bylaws of the Company or Subsidiary, or (iii) any law, order, rule or
regulation, or to the best of the Company's knowledge, any writ, injunction,
judgment or decree of any court, government or governmental agency or body,
domestic or foreign, having jurisdiction over the Company or Subsidiary or over
its respective properties or assets, which violation or default would have a
material adverse effect on the business, prospects, financial condition or
results of operations of the Company and Subsidiary taken as a whole. No
consent, approval, authorization or order of, or qualification with, any court,
government or governmental agency or body, domestic or foreign, having
jurisdiction over the Company or Subsidiary or over its respective properties or
assets is required for the execution and delivery of any Transaction Agreement
and the consummation by the Company of the transactions herein and therein
contemplated, except such as may be required under the Securities Act or under
state or other securities or blue sky laws, all of which requirements have been,
or in accordance therewith will be, satisfied in all material respects.

         (e) There is not any pending or, to the best of the Company's
knowledge, threatened, action, suit, claim or proceeding against the Company or
Subsidiary, or any of its officers or any of its properties, assets or rights,
before any court, government or governmental agency or body, domestic or
foreign, having jurisdiction over the Company or Subsidiary or over its officers
or properties or otherwise that (i) is reasonably likely to result in any
material adverse change in the business, prospects, financial condition or
results of operations of the Company and Subsidiary taken as a whole or might
materially and adversely affect their properties, assets or rights taken as a
whole, (ii) might prevent consummation of the transactions contemplated by the
Transaction Agreements, or (iii) will be required to be disclosed in the
Registration Statement, except to the extent heretofore disclosed in the SEC
Documents.

         (f) As of the date of this Agreement, the authorized capital stock of
the Company consists of 50,000,000 shares of Common Stock, of which 28,143,179
shares of Common Stock are outstanding, and 10,000,000 shares of preferred
stock, none of which is outstanding. All outstanding capital stock of Subsidiary
is owned beneficially and of record by the Company. Each of such outstanding
shares of Common Stock and each outstanding share of capital stock of
Subsidiary, is validly authorized, validly issued, fully paid, and
nonassessable, has not been issued and is not owned or held in violation of any



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preemptive or similar right of stockholders. As of the date of this Agreement,
there is no commitment, plan, or arrangement to issue, and no outstanding
option, warrant, or other right calling for the issuance of, any share of
capital stock of or any security or other instrument convertible into or
exchangeable for capital stock of the Company or Subsidiary. As of the date of
this Agreement, there is outstanding no security or other instrument convertible
into or exchangeable for capital stock of the Company or Subsidiary. The Shares
and the Warrant Shares have been duly authorized for issuance and sale to the
Purchaser pursuant hereto and the Warrants, respectively, and, when issued and
delivered by the Company against payment therefor in accordance with the terms
of this Agreement and the relevant Warrant or Warrants, respectively, will be
duly and validly issued and fully paid and nonassessable, and will be sold free
and clear of any pledge, lien, security interest, encumbrance, claim or
equitable interest of any kind; and no preemptive or similar right, co-sale
right, registration right, right of first refusal or other similar right of
stockholders exists with respect to any of the Shares or Warrant Shares or the
issuance and sale thereof other than those that have been expressly waived prior
to the date hereof and those that will automatically expire upon the execution
hereof. No further approval or authorization of any stockholder, the Board of
Directors of the Company or others is required for the issuance and sale or
transfer of the Shares, the Warrants, or the Warrant Shares, except as may be
required under the Securities Act, the rules and regulations promulgated
thereunder or under state or other securities or blue sky laws. The description
of the Company's stock option, stock bonus and other stock plans or
arrangements, and the options or other rights granted and exercised thereunder,
set forth in the SEC Documents accurately and fairly presents in all material
respects the information required to be shown with respect to such plans,
arrangements, options and rights under the Securities Act, the Exchange Act, and
the rules and regulations promulgated thereunder. The Company has authorized and
has reserved and covenants to continue to reserve, free of preemptive rights and
other similar contractual rights of stockholders, a sufficient number of its
authorized, but unissued, shares of its Common Stock to cover the Warrant
Shares.

         (g) Deloitte & Touche LLP (the "AUDITORS"), which has examined the
consolidated financial statements of the Company, together with the related
schedules and notes, for the year ended December 31, 2002, filed with the
Commission as a part of the SEC Documents, and which, pursuant to the rules and
regulations of the Commission are to be included in the Registration Statement,
are independent accountants within the meaning of the Securities Act, the
Exchange Act, and the rules and regulations promulgated thereunder; the audited
consolidated financial statements of the Company, together with the related
schedules and notes, and the unaudited financial information, forming part of
the SEC Documents, fairly present the financial position and the results of
operations of the Company at the respective dates and for the respective periods
to which they apply; and all audited consolidated financial statements of the
Company, together with the related schedules and notes, and the unaudited
consolidated financial information, filed with the Commission as part of the SEC
Documents, as the same might have been amended, complied as to form in all
material respects with applicable accounting requirements and with the rules and
regulations of the Commission with respect hereto, have been prepared in


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accordance with generally accepted accounting principles consistently applied
throughout the periods involved except as may be otherwise stated therein
(except as may be indicated in the notes thereto or as permitted by the rules
and regulations of the Commission) and fairly present, subject in the case of
the unaudited consolidated financial statements, to customary year end audit
adjustments, the financial position of the Company as at the dates thereof and
the results of its operations and cash flows. The selected and summary
consolidated financial and statistical data included in the SEC Documents
present fairly the information shown therein and have been compiled on a basis
consistent with the audited consolidated financial statements presented therein.
No other financial statements or schedules are required to be included in the
SEC Documents.

         (h) Subsequent to the respective dates as of which information is given
in the SEC Documents, there has not been (i) any material adverse change in the
business, prospects, financial condition or results of operations of the Company
and Subsidiary taken as a whole, (ii) any transaction committed to or
consummated that is material to the Company and Subsidiary taken as a whole,
(iii) any obligation, direct or contingent, that is material to the Company and
Subsidiary taken as a whole incurred by the Company or Subsidiary, except such
obligations as have been incurred in the ordinary course of business, (iv) any
change in the capital stock or outstanding indebtedness of the Company or
Subsidiary that is material to the Company and Subsidiary taken as whole, (v)
any dividend or distribution of any kind declared, paid, or made on the capital
stock of the Company, or (vi) any loss or damage (whether or not insured) to the
property of the Company or Subsidiary which has a material adverse effect on the
business, prospects, condition (financial or otherwise), or results of
operations of the Company and Subsidiary taken as a whole.

         (i) Each of the Company and Subsidiary has good and marketable title to
all properties and assets described in the SEC Documents as owned by it, free
and clear of any pledge, lien, security interest, encumbrance, claim or
equitable interest, other than such as would not have a material adverse effect
on the business, prospects, financial condition or results of operations of the
Company and Subsidiary taken as a whole. The agreements to which the Company or
Subsidiary is a party described in the SEC Documents are legal, valid and
binding agreements, enforceable by the Company or Subsidiary, as applicable, in
accordance with their terms (except as such enforceability may be subject to the
laws of general application relating to bankruptcy, insolvency and the relief of
debtors and rules of law governing specific performance, injunctive relief or
other equitable remedies), and, to the best of the Company's knowledge, the
other contracting party or parties thereto are not in breach or default under
any of such agreements. Each of the Company and Subsidiary has valid and
enforceable leases for all properties described in the SEC Documents as leased
by it. Except as set forth in the SEC Documents, each of the Company and
Subsidiary owns or leases all such properties as are necessary to its respective
operations as now conducted and as described in the SEC Documents.

         (j) Each of the Company and Subsidiary has timely filed all respective
federal, state, local and foreign tax returns required to be filed by it and has
paid all taxes shown thereon as due, and there is no tax deficiency that has
been or, to the best of the Company's knowledge, is likely to be asserted
against the Company or Subsidiary if audited, which might have a material
adverse effect on the business, prospects, financial condition or results of
operations of the Company and Subsidiary taken as a whole, and all tax
liabilities are adequately provided for on the books of the Company and
Subsidiary.


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         (k) The Company and Subsidiary are insured by insurers of recognized
financial responsibility against such losses and risks and in such amounts as
management of the Company believes to be prudent and customary in the businesses
in which the Company and Subsidiary are engaged. Neither the Company nor
Subsidiary has any reason to believe that it will not be able to renew its
existing insurance coverage as and when such coverage expires or to obtain
similar coverage from similar insurers as may be necessary to continue its
business at a cost that would not materially and adversely affect the condition,
financial or otherwise, or the earnings, business or operations of the Company
and its Subsidiary, taken as a whole.

         (l) No labor disturbance by the employees of the Company or Subsidiary
exists or, to the best of the Company's knowledge, is imminent. The Company is
not aware of any existing or imminent labor disturbance by the employees of any
principal suppliers or customers of the Company or Subsidiary that might be
expected to result in any material adverse change in the business, prospects,
condition (financial or otherwise), or results of operations of the Company and
Subsidiary taken as a whole. No collective bargaining agreement exists with any
of the Company's or Subsidiary's employees and, to the best of the Company's
knowledge, no such agreement is imminent.

         (m) Each of the Company and Subsidiary owns or possesses adequate
rights to use all patents, patent rights, inventions, trade secrets, know-how,
trademarks, service marks, trade names, logos, and copyrights described or
referred to in the SEC Documents as owned by or used by it or that are necessary
to conduct its respective businesses as described in the SEC Documents; neither
the Company nor Subsidiary has received any notice of, or has knowledge of, any
infringement of or conflict with asserted rights of the Company or Subsidiary by
others with respect to any patents, patent rights, inventions, trade secrets,
know-how, trademarks, service marks, trade names, logos, or copyrights described
or referred to in the SEC Documents as owned by or used by it; and neither the
Company nor Subsidiary has received any notice of, or has knowledge of, any
infringement of, or conflict with, asserted rights of others with respect to any
patents, patent rights, inventions, trade secrets, know-how, trademarks, service
marks, trade names, logos, or copyrights described or referred to in the SEC
Documents as owned by or used by it or which, individually or in the aggregate,
in the event of an unfavorable decision, ruling or finding, would have a
material adverse effect on the business, prospects, financial condition or
results of operations of the Company and Subsidiary taken as a whole.

         (n) The Company has been advised concerning the Investment Company Act
of 1940, as amended (the "INVESTMENT COMPANY ACT"), and the rules and
regulations thereunder, and has in the past conducted, and intends in the
future, to conduct its affairs in such a manner as to ensure that it is not and
will not become an "investment company" or a company "controlled" by an
"investment company" within the meaning of the Investment Company Act and such
rules and regulations.

         (o) Neither the Company nor Subsidiary has, and no person or entity
acting on behalf or at the request of the Company or Subsidiary has, at any time
during the last five years (i) made any unlawful contribution to any candidate
for foreign office or failed to disclose fully any contribution in violation of
law, or (ii) made any payment to any federal or state governmental officer or
official, or other person charged with similar public or quasi-public duties,
other than payments required or permitted by the laws of the United States or
any other applicable jurisdiction.


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         (p) Neither the Company nor Subsidiary has taken or will take, directly
or indirectly, any action designed to, or that might reasonably be expected to
cause or result in, stabilization in violation of law, or illegal manipulation
of the price of the Common Stock, to facilitate the sale or resale of the Shares
or the Warrant Shares.

         (q) Each of the Company and Subsidiary is in compliance in all material
respects with all rules, laws and regulations relating to the use, treatment,
storage and disposal of toxic substances and protection of health or the
environment ("ENVIRONMENTAL LAWS") that are applicable to its business. Neither
the Company nor Subsidiary has received notice from any governmental authority
or third party of an asserted claim under Environmental Laws, which claim is
required to be disclosed in the SEC Documents. To the best knowledge of the
Company, neither the Company nor Subsidiary is likely to be required to make
future material capital expenditures to comply with Environmental Laws. No
property which is owned, leased or occupied by the Company or Subsidiary has
been designated as a Superfund site pursuant to the Comprehensive Response,
Compensation, and Liability Act of 1980, as amended (42 U.S.C. ss. 9601, et
seq.), or otherwise designated as a contaminated site under applicable state or
local law. Neither the Company nor Subsidiary is in material violation of any
federal or state law or regulation relating to occupational safety or health.

         (r) The books, records and accounts of each of the Company and
Subsidiary accurately and fairly reflect, in reasonable detail, the transactions
in, and dispositions of, the assets of, and the results of operations of, the
Company and Subsidiary, as applicable, all to the extent required by generally
accepted accounting principles. Each of the Company and Subsidiary maintains a
system of internal accounting controls sufficient to provide reasonable
assurances that (i) transactions are executed in accordance with management's
general or specific authorizations, (ii) transactions are recorded as necessary
to permit preparation of financial statements in accordance with generally
accepted accounting principles and to maintain asset accountability, (iii)
access to assets is permitted only in accordance with management's general or
specific authorization and (iv) the recorded accountability for assets is
compared with the existing assets at reasonable intervals and appropriate action
is taken with respect to any differences.

         (s) There are no outstanding loans, advances (except normal advances
for business expenses in the ordinary course of business) or guarantees of
indebtedness by the Company or Subsidiary to, or for the benefit of, any of the
officers, directors, or director-nominees of the Company or Subsidiary or any of
the members of the families of any of them.

         (t) The Company represents and warrants that no agent, broker,
investment banker, person or firm acting on behalf of or under the authority of
the Company is or will be entitled to any broker's or finder's fee or any other
commission directly or indirectly in connection with the transactions
contemplated herein. The Company further agrees to indemnify the Purchaser for
any claims, losses or expenses incurred by the Purchaser as a result of the
representation in this paragraph being untrue.


                                       10
<PAGE>

         (u) No stockholder of the Company has any right (which has not been
waived or has not expired by reason of lapse of time following notification of
the Company's intent to file the Registration Statement) to request or require
the Company to register the sale of any shares owned by such stockholder under
the Securities Act on the Registration Statement.

         SECTION 2.02 REPRESENTATIONS, WARRANTIES AND COVENANTS OF THE
PURCHASER. The Purchaser represents and warrants to the Company as follows:

         (a) If Purchaser is a business entity, the Purchaser is a company duly
organized, validly existing and in good standing under the laws of its
jurisdiction of formation.

         (b) The Purchaser has full legal right, power and authority to enter
into this Agreement and to perform the transactions contemplated hereby. This
Agreement has been duly authorized, executed and delivered by the Purchaser. The
execution, delivery and performance of this Agreement by the Purchaser and the
consummation of the transactions herein contemplated will not violate any
provision of the organizational documents of the Purchaser (if the Purchaser is
a business entity), and will not result in the creation of any lien, charge,
security interest or encumbrance upon any assets or property of the Purchaser
pursuant to the terms or provisions of, or will not conflict with, result in the
breach or violation of, or constitute, either by itself or upon notice or the
passage of time or both, a default under any agreement, mortgage, deed of trust,
lease, franchise, license, indenture, permit or other instrument to which the
Purchaser is a party or by which the Purchaser or any of its assets or
properties may be bound or affected or any statute or any authorization,
judgment, decree, order, rule or regulation of any court or any regulatory body,
administrative agency or other governmental body applicable to the Purchaser or
any of its properties. No consent, approval, authorization or other order of any
court, regulatory body, administrative agency or other governmental body is
required for the execution, delivery and performance of this Agreement or the
consummation by the Purchaser of the transactions contemplated hereby. Assuming
the valid execution hereof by the Company, this Agreement will constitute the
legal, valid and binding obligation of the Purchaser, enforceable in accordance
with its terms, except as enforceability may be limited by applicable
bankruptcy, insolvency, reorganization, moratorium or similar laws affecting
creditors' rights generally and except as enforceability may be subject to
general principles of equity (regardless of whether such enforceability is
considered in a proceeding in equity or at law) and except as the
indemnification agreements of the Purchaser in Section 3.03 hereof may be
legally unenforceable.


                                       11
<PAGE>

         (c) There are no legal or governmental actions, suits or proceedings
pending or, to the Purchaser's knowledge, threatened to which the Purchaser is
or may be a party which seeks to prevent or restrain the transactions
contemplated by this Agreement or to recover damages as a result of the
consummation of such transactions. To the knowledge of the Purchaser, the
Purchaser has not been and is not currently the subject of an investigation or
inquiry by the Commission, National Association of Securities Dealers, Inc.,
NASD Regulation, Inc., or any state securities commission.

         (d) The Purchaser is knowledgeable, sophisticated and experienced in
making, and is qualified to make, decisions with respect to investments in
shares representing an investment decision like that involved in the purchase of
the Shares, the Warrants, and the Warrant Shares, including investments in
securities issued by the Company. The Purchaser is not a "dealer" within the
meaning of the Securities Act or a "broker" or "dealer" within the meaning of
the Exchange Act. The Purchaser is able to bear the economic risk of loss of the
Purchaser's entire investment in the Shares, the Warrants, and the Warrant
Shares.

         (e) The Purchaser has requested, received, reviewed and considered all
information it deems relevant in making an informed decision to purchase the
Shares and the Warrants. The Purchaser understands that the Company is still in
the development stage and does not have operating revenues.

         (f) The Purchaser is acquiring the Shares and the Warrants in the
ordinary course of its business and for its own account for investment only and
with no present intention of distributing any of such Shares in violation of the
Securities Act or entering into any arrangement or understanding with any other
person regarding the distribution of such Shares in violation of the Securities
Act (it being understood that the foregoing does not limit the Purchaser's right
to sell Shares pursuant to the Registration Statement).

         (g) Purchaser understands that the Company is raising additional
capital from investors on terms similar to this Agreement but with different
allocations of shares between the First Tranche and the Second Tranche, and with
proportional adjustments to the number of shares underlying the $1.00 Warrants
and the $1.30 Warrants (such number being fifty percent (50%) of the number of
Shares purchased in the respective tranches). Purchaser understands that the
Company will require substantially more capital than the amount raised in this
offering (and the amounts raised from other investors concurrently herewith) in
order to complete the steps necessary to bring any products to market and
generate revenues. Purchaser acknowledges that these matters are discussed in
more detail in the SEC Reports under the heading "Management's Discussion and
Analysis." Purchaser understands that any additional capital raised by the
Company in the future may be on terms similar to or different from the terms of
this Agreement, and such terms may be more or less favorable to investors than
the terms of this Agreement.

         (h) The Purchaser is an "accredited investor" as defined in Rule 501 of
Regulation D under the Securities Act, and has provided true and correct
information on the Accredited Investor Questionnaire attached hereto as Exhibit
B.


                                       12
<PAGE>

         (i) Purchaser represents and warrants that no agent, broker, investment
banker, person or firm acting on behalf of or under the authority of Purchaser
is or will be entitled to any broker's or finder's fee or any other commission
directly or indirectly in connection with the transactions contemplated herein.
Purchaser further agrees to indemnify the Company for any claims, losses or
expenses incurred by the Company as a result of the representation in this
paragraph being untrue.

         (j) Except for the representations and warranties contained in this
Section 2.02, the Purchaser makes no representation or warranty to the Company,
express or implied, in connection with the transactions contemplated by this
Agreement.

         SECTION 2.03 SURVIVAL OF REPRESENTATIONS, WARRANTIES AND AGREEMENTS.
Notwithstanding any investigation made by any party to this Agreement, all
covenants, agreements, representations and warranties made by the Company and
the Purchaser herein and in the certificates delivered pursuant hereto shall
survive the execution of this Agreement, the delivery to the Purchaser of the
Shares and the Warrants being purchased and the payment therefor, for a period
of two years following the Second Closing, or if there is no Second Closing, two
years following the First Closing.

                                   ARTICLE III

                                    COVENANTS

         SECTION 3.01 COVENANTS OF THE COMPANY.

         (a) (i) As soon as practicable, but in any event no later than May 28,
2004, the Company shall prepare and file with the Commission a registration
statement on Form SB-2 or other applicable form as determined by the Company
(the "REGISTRATION STATEMENT") for the purpose of registering the sale of the
Shares and the Warrant Shares by the Purchaser from time to time on the
facilities of any securities exchange or trading system on which the Common
Stock is then traded or in privately-negotiated transactions, which Registration
Statement shall contain all material information required to be set forth
therein and all material information disclosed to the Purchaser. For purposes of
this Section 3.01(a), the terms "SHARES" and "WARRANT SHARES" shall include any
other securities of the Company issued in exchange for the Shares or Warrant
Shares, as a dividend on the Shares or the Warrant Shares, or in connection with
a stock split or other reorganization transaction affecting the Shares or the
Warrant Shares. The Company shall use its commercially reasonable efforts to
cause the Registration Statement to become effective under the Securities Act as
soon as practicable, and in any event on or prior to August 30, 2004. In the
event that the Registration Statement should not be filed on or prior to May 28,
2004 or be declared effective under the Securities Act on or prior to August 30,
2004 (in either case, an "EVENT DATE"), (A) then on each monthly anniversary
following an Event Date until filing or effectiveness of the Registration
Statement, as applicable, the Company shall issue to the Purchaser (subject to
the limitations stated in Section 1.01(c)), as liquidated damages and not as a
penalty, the number of shares of Common Stock equal to 2% of the Shares
purchased by the Purchaser in the First Tranche.

                                       13
<PAGE>

                  (ii) The Company shall prepare and file with the Commission
such amendments and supplements to the Registration Statement and the prospectus
forming a part thereof as may be necessary to keep the Registration Statement
effective until the earliest date, after the date on which all of the Shares
have been purchased pursuant to this Agreement or the obligation of the
Purchaser to purchase the Shares pursuant to this Agreement has been terminated,
on which (i) all the Shares have been disposed of pursuant to the Registration
Statement, (ii) all of the Shares then held by the Purchaser may be sold within
a three month period under the provisions of Rule 144 without limitation as to
volume, whether pursuant to Rule 144(k) or otherwise, or (iii) the Company has
determined that all Shares then held by the Purchaser may be sold without
restriction under the Securities Act and has removed any stop transfer
instructions relating to such Shares and offered to cause to be removed any
restrictive legends on the certificates, if any representing such Shares (the
period between the Effective Date and the earliest of such dates is referred to
herein as the "REGISTRATION PERIOD"). At any time after the end of the
Registration Period, the Company may withdraw the Registration Statement and its
obligations under this Section 3.01(a) shall automatically terminate.

                  (iii) The Company shall not be obligated to prepare and file a
post-effective amendment or supplement to the Registration Statement or the
prospectus constituting a part thereof during the continuance of a Blackout
Event. A "BLACKOUT EVENT" means any of the following: (a) the possession by the
Company of material information that is not ripe for disclosure in a
registration statement or prospectus, as determined in good faith by the Chief
Executive Officer or the Board of Directors of the Company or that disclosure of
such information in the Registration Statement or the prospectus constituting a
part thereof would be materially detrimental to the business and affairs of the
Company; or (b) any material engagement or activity by the Company which would,
in the good faith determination of the Chief Executive Officer or the Board of
Directors of the Company, be materially adversely affected by disclosure in a
registration statement or prospectus at such time. In each event that there
should be in excess of two Blackout Events during any year commencing on the
date of this Agreement or any anniversary hereof, or in each event that any
Blackout Event should continue in excess of 30 days, for each such Blackout
Event and for each 30-day period or portion thereof following the aforementioned
initial 30 days, the exercise price of the Warrants shall be decreased by 2%
from the exercise price thereof in effect immediately prior to such adjustment.

                  (iv) At least two (2) Business Days prior to the filing with
the Commission of the Registration Statement (or any amendment thereto) or the
prospectus forming a part thereof (or any supplement thereto), the Company shall
provide draft copies thereof to the Purchaser and shall consider incorporating
into such documents such comments as the Purchaser (and its counsel) may propose
to be incorporated therein. Notwithstanding the foregoing, no prospectus
supplement, the form of which has previously been provided to the Purchaser,
need be delivered in draft form to the Purchaser.

                  (v) The Company shall promptly notify the Purchaser upon the
occurrence of any of the following events in respect of the Registration
Statement or the prospectus forming a part thereof: (i) receipt of any request
for additional information from the Commission or any other federal or state
governmental authority during the Registration Period, the response to which
would require any amendments to the Registration Statement; (ii) the issuance by
the Commission or any other federal or state governmental authority of any stop
order suspending the effectiveness of the Registration Statement or the
initiation of any proceedings for that purpose; or (iii) receipt of any
notification with respect to the suspension of the qualification or exemption
from qualification of any of the Shares for sale in any jurisdiction or the
initiation or threatening of any proceeding for such purpose.


                                       14
<PAGE>

                  (vi) The Company shall furnish to the Purchaser with respect
to the Shares and Warrant Shares registered under the Registration Statement
(and to each underwriter, if any, of such Shares and Warrant Shares) such number
of copies of prospectuses and such other documents as the Purchaser may
reasonably request, in order to facilitate the public sale or other disposition
of all or any of the Shares and Warrant Shares by the Purchaser pursuant to the
Registration Statement.

                  (vii) The Company shall file or cause to be filed such
documents as are required to be filed by the Company for normal state securities
law or "blue sky" clearance in states specified in writing by the Purchaser;
provided, however, that the Company shall not be required to qualify to do
business or consent to service of process in any jurisdiction in which it is not
now so qualified or has not so consented.

                  (viii) With a view to making available to the Purchaser the
benefits of Rule 144, the Company agrees, throughout the Registration Period and
so long as the Purchaser owns Shares or Warrants purchased pursuant to this
Agreement, to:

                           (A) comply with the provisions of paragraph (c) of
Rule 144; and

                           (B) file with the Commission in a timely manner all
reports and other documents
required to be filed by the Company pursuant to Section 13, 14 or 15(d) under
the Exchange Act; and, if at any time it is not required to file such reports
but in the past had been required to or did file such reports, it will, upon the
request of the Purchaser, make available other information as required by, and
so long as necessary to permit sales of its Shares pursuant to, Rule 144.

                  (ix) The Company shall bear all expenses incurred by it in
connection with the procedures in paragraphs (i) through (ix) of this Section
3.01(a) and the registration of the Shares and Warrant Shares pursuant to the
Registration Statement. The Company shall not be responsible for any expenses
incurred by the Purchaser in connection with its sale of the Shares or Warrant
Shares or its participation in the procedures in paragraphs (i) through (ix) of
this Section 3.01(a), including, without limitation, any fees and expenses of
counsel or other advisers to the Purchaser and any underwriting discounts,
brokerage fees and commissions incurred by the Purchaser.

         (b) (i) The Company may refuse to register (or refuse to permit its
transfer agent to register) any transfer of any Shares not made in accordance
with this Section 3.01(b) and for such purpose may place stop order instructions
with its transfer agent with respect to the Shares.


                                       15
<PAGE>

         (c) So long as the Registration Statement is effective covering the
resale of Shares then still owned by the Purchaser, the Company shall furnish to
the Purchaser:

                  (i) as soon as practicable after available, one copy of (A)
its Annual Report to Stockholders (which Annual Report shall contain financial
statements audited in accordance with generally accepted accounting principles
by a firm of certified public accountants), (B) upon written request, its Annual
Report on Form 10-KSB, (C) upon written request, its Quarterly Reports on Form
10-QSB, (D) upon written request, its Current Reports on Form 8-K, and (E) a
full copy of the Registration Statement (the foregoing, in each case, excluding
exhibits); and

                  (ii) upon the written request of the Purchaser, all exhibits
excluded by the parenthetical to subparagraph (i)(E) of this Section 3.01(c).

         (d) The Company will maintain a transfer agent and, if necessary under
the jurisdiction of incorporation of the Company, a registrar (which may be the
same entity as the transfer agent) for its Common Stock, which transfer agent
and registrar shall be reasonably satisfactory to the Purchaser.

         (e) The Company shall promptly comply with the Sarbanes-Oxley Act of
2002 and the regulations promulgated pursuant thereto if it is not in compliance
at the date hereof.

         (f) Until the earlier of the termination of this Agreement and the
Second Closing (the earlier of such events, the "RELEASE TIME"), no dividend or
liquidating or other distribution or stock split shall be authorized, declared,
paid, or effected by the Company in respect of the outstanding shares of capital
stock of the Company. Until the Release Time, no direct or indirect redemption,
purchase, or other acquisition shall be made by the Company or any affiliate
thereof of shares of capital stock of the Company. This covenant shall not apply
if there is no Second Closing, either because no Second Closing is provided for
in this Agreement, or the last date for the Second Closing has expired.

         (g) Until the Release Time, and subject to the Company's obligations
under Regulation FD promulgated by the Commission and/or execution by the
Purchaser of an appropriate confidentiality agreement, the Company will afford
the officers, directors, employees, counsel, agents, investment bankers,
accountants, and other representatives of the Purchaser free and full access to
the plants, properties, books, and records of the Company, will permit them to
make extracts from and copies of such books and records, and will from time to
time furnish the Purchaser with such additional financial and operating data and
other information as to the business, prospects, financial condition, and
results of operations of the Company as the Purchaser from time to time may
request. This covenant shall not apply if there is no Second Closing, either
because no Second Closing is provided for in this Agreement, or the last date
for the Second Closing has expired.


                                       16
<PAGE>

         (h) Before the Company releases any information concerning this
Agreement or any of the transactions contemplated by this Agreement which is
intended for, or may result in, public dissemination thereof, the Company shall
cooperate with the Purchaser, shall furnish drafts of all documents or proposed
oral statements to the Purchaser for comment, and shall not release any such
information without the written consent of Purchaser, which consent shall not be
unreasonably withheld. Nothing contained herein shall prevent the Company from
releasing any information if required to do so by law.

         (i) The Company shall timely prepare and file any declaration or filing
necessary to comply with any transfer tax statutes that require any such filing
before the relevant Closing.

         (j) The Company shall obtain make such state securities law or "blue
sky" filings and obtain such state securities law or "blue sky" filings as shall
be reasonably requested by the Purchaser, provided, however, that the Company
shall not be required to qualify to do business or to become subject to general
service of process in any such jurisdiction.

         SECTION 3.02 COVENANTS OF THE PURCHASER.

         (a) The Purchaser agrees to comply in all material respects with all
federal and state securities laws and the rules and regulations promulgated
thereunder in connection with any sale by it of the Shares, the Warrants and the
Warrant Shares, whether or not such sale is pursuant to the Registration
Statement. In connection with the sale of any Shares pursuant to the
Registration Statement, but without limiting the generality of the foregoing
sentence, the Purchaser shall (i) comply with the provisions of Regulation M
promulgated under the Exchange Act, and (ii) deliver to the purchaser of Shares
the prospectus forming a part of the Registration Statement and all relevant
supplements thereto which have been provided by the Company to the Purchaser on
or prior to the applicable delivery date.

         (b) The Purchaser will cooperate with the Company in all respects in
connection with the performance by the Company of its obligations under Section
3.01(a), including timely supplying all information reasonably requested by the
Company (which shall include all information regarding the Purchaser, and any
person who beneficially owns Shares held by the Purchaser within the meaning of
Rule 13d-3 promulgated under the Exchange Act, and the proposed manner of sale
of the Shares required to be disclosed in the Registration Statement) and
executing and returning all documents reasonably requested in connection with
the registration and sale of the Shares. During any periods that the Company is
unable to meet its obligations hereunder with respect to the registration of the
Shares solely because the Purchaser fails to furnish such information within
three Business Days of the Company's request, any liquidated damages that are
accruing at such time shall be tolled and any Event Date that may otherwise
occur solely because of such delay shall be suspended, until such information is
delivered to the Company.

          (c) Neither the Purchaser nor any entity controlling it, under its
control or under common control with it has, prior to the execution of this
Agreement, and will not, for a period of 18 months following the execution of
this Agreement, carry a net short position (as defined below) in the Common
Stock of the Company. A "net short position" means that the aggregate short
position of the Purchaser with respect to the Common Stock exceeds the number of
shares of Common Stock owned by the Purchaser, which for such purpose shall be
deemed to include all of the Shares plus the Warrant Shares. For purposes
hereof, a short position will include any derivative instruments such as a put
option, collar, swap or any other instrument which would result in a short
position.


                                       17
<PAGE>

         (d) In connection with the sale of any Shares pursuant to the
Registration Statement, the Purchaser shall deliver to the purchaser thereof the
prospectus forming a part of the Registration Statement and all relevant
supplements thereto which have been provided by the Company to the Purchaser on
or prior to the applicable delivery date, all in accordance with the
requirements of the Securities Act and the rules and regulations promulgated
thereunder and any applicable blue sky laws.

         (e) If at any time or from time to time after the Effective Date, the
Company notifies the Purchaser in writing that the Registration Statement or the
prospectus forming a part thereof (taking into account any prior amendments or
supplements thereto) contains any untrue statement of a material fact or omits
to state a material fact necessary to make the statements therein, in light of
the circumstances under which they are made, not misleading, the Purchaser shall
not offer or sell any Shares or engage in any other transaction involving or
relating to the Shares (other than purchases of Shares pursuant to this
Agreement), from the time of the giving of notice with respect to such untrue
statement or omission until the Purchaser receives written notice from the
Company that such untrue statement or omission no longer exists or has been
corrected or disclosed in an effective post-effective amendment to the
Registration Statement or a valid prospectus supplement to the prospectus
forming a part thereof.

         (f) The Purchaser acknowledges and understands that the Shares, the
Warrants, and the Warrant Shares are (or upon the issuance thereof will be)
"restricted securities" as defined in Rule 144. The Purchaser hereby agrees not
to offer or sell (as such terms are defined in the Securities Act and the rules
and regulations promulgated thereunder) any Shares, Warrants, or Warrant Shares
unless such offer or sale is made (a) pursuant to an effective registration of
such securities under the Securities Act, or (b) pursuant to an available
exemption from the registration requirements of the Securities Act. The
Purchaser agrees that it will not engage in hedging transactions with regard to
the Shares, the Warrants, and the Warrant Shares other than in compliance with
Section 3.02(c) and the Securities Act. A proposed transfer shall be deemed to
comply with this Section 3.02(f) if the Purchaser delivers to the Company a
legal opinion in form and substance reasonably satisfactory to the Company from
counsel reasonably satisfactory to the Company to the effect that such transfer
complies with this Section 3.02(f).

         SECTION 3.03 INDEMNIFICATION.

         (a) For the purpose of this paragraph (a) of this Section 3.03: (i) the
term "PURCHASER AFFILIATE" shall mean any person who controls the Purchaser
within the meaning of Section 15 of the Securities Act or Section 20 of the
Exchange Act; and (ii) the term "REGISTRATION STATEMENT" shall include any final
prospectus, exhibit, supplement or amendment included in or relating to the
Registration Statement referred to in Section 3.01(a).

                  (i) The Company agrees to indemnify and hold harmless the
Purchaser and each Purchaser Affiliate, against any losses, claims, damages,
liabilities or expenses, joint or several, to which such Purchaser or such
Purchaser Affiliate may become subject, under the Securities Act, the Exchange
Act, or any other federal or state statutory law or regulation, or at common law
or otherwise (including in settlement of any litigation, if such settlement is


                                       18
<PAGE>

effected with the written consent of the Company, which consent shall not be
unreasonably withheld), insofar as such losses, claims, damages, liabilities or
expenses (or actions in respect thereof as contemplated below) arise out of or
are based upon (A) any untrue statement or alleged untrue statement of any
material fact contained in the Registration Statement, as amended as of the
Effective Date, including any information deemed to be a part thereof as of the
time of effectiveness pursuant to paragraph (b) of Rule 430A, or pursuant to
Rule 434 promulgated under the Securities Act, or the prospectus, in the form
first filed with the Commission pursuant to Rule 424(b) of the Regulations, or
filed as part of the Registration Statement at the time of effectiveness if no
Rule 424(b) filing is required (the "PROSPECTUS"), or any amendment or
supplement thereto, (B) the omission or alleged omission to state in the
Registration Statement as of the Effective Date a material fact required to be
stated therein or necessary to make the statements in the Registration Statement
or any post-effective amendment or supplement thereto, or in the Prospectus or
any amendment or supplement thereto, not misleading, in each case in the light
of the circumstances under which the statements contained therein were made, or
(C) any inaccuracy in the representations and warranties of the Company
contained in this Agreement, or any failure of the Company to perform its
obligations hereunder, and will reimburse the Purchaser and each such Purchaser
Affiliate for any legal and other expenses as such expenses which are reasonably
incurred by the Purchaser or such Purchaser Affiliate in connection with
investigating, defending, settling, compromising or paying any such loss, claim,
damage, liability, expense or action; provided, however, that the Company will
not be liable in any such case to the extent that any such loss, claim, damage,
liability or expense arises out of or is based upon (A) an untrue statement or
alleged untrue statement or omission or alleged omission made in the
Registration Statement, the prospectus included therein, or any amendment or
supplement thereto in reliance upon, and in conformity with, written information
furnished to the Company by the Purchaser expressly for use therein, or (B) the
failure of the Purchaser to comply with the covenants and agreements contained
in Section 3.02 hereof, or (C) the inaccuracy of any representations made by the
Purchaser herein or (D) any statement or omission in any Prospectus that is
corrected or disclosed in any subsequent Prospectus that was delivered to the
Purchaser prior to the pertinent sale or sales by the Purchaser.

                  (ii) The Purchaser will indemnify and hold harmless the
Company, each of its directors, each of its officers who signed the Registration
Statement and each person, if any, who controls the Company within the meaning
of the Securities Act and the Exchange Act, against any losses, claims, damages,
liabilities or expenses to which the Company, each of its directors, each of its
officers who signed the Registration Statement or controlling person may become
subject, under the Securities Act, the Exchange Act, or any other federal or
state statutory law or regulation, or at common law or otherwise (including in
settlement of any litigation, if such settlement is effected with the written
consent of such Purchaser) insofar as such losses, claims, damages, liabilities
or expenses (or actions in respect thereof as contemplated below) arise out of
or are based upon (A) any failure to comply with the covenants and agreements
contained in Section 3.02 hereof, (B) the inaccuracy of any representation made
by the Purchaser herein, or (C) any (I) untrue or alleged untrue statement of
any material fact contained in the Registration Statement, the Prospectus, or
any amendment or supplement thereto, or (II) omission or alleged omission to
state in the Registration Statement, the Prospectus or any amendment or
supplement thereto a material fact required to be stated therein or necessary to
make the statements in the Registration Statement or any amendment or supplement


                                       19
<PAGE>

thereto, in the prospectus included therein, or any amendment or supplement
thereto, not misleading, in each case in the light of the circumstances under
which they were made; provided, that the Purchaser's indemnification obligation
under this clause (C) shall apply to the extent, and only to the extent, that
such untrue statement or alleged untrue statement or omission or alleged
omission was made in the Registration Statement, such prospectus, or any
amendment or supplement thereto, in reliance upon and in conformity with written
information furnished to the Company by the Purchaser expressly for use therein,
and will reimburse the Company, each of its directors, each of its officers who
signed the Registration Statement or controlling person for any legal and other
expense reasonably incurred by the Company, each of its directors, each of its
officers who signed the Registration Statement or controlling person in
connection with investigating, defending, settling, compromising or paying any
such loss, claim, damage, liability, expense or action.

                  (iii) Promptly after receipt by an indemnified party under
this Section 3.03 of notice of the threat or commencement of any action, such
indemnified party will, if a claim in respect thereof is to be made against an
indemnifying party under this Section 3.03, promptly notify the indemnifying
party in writing thereof; provided, the omission so to notify the indemnifying
party will not relieve it from any liability which it may have to any
indemnified party for contribution (except as provided in paragraph (iv)) or
otherwise than under the indemnity agreement contained in this Section 3.03 or
to the extent it is not prejudiced as a result of such failure. In case any such
action is brought against any indemnified party and such indemnified party seeks
or intends to seek indemnity from an indemnifying party, the indemnifying party
will be entitled to participate in, and, to the extent that it may wish, jointly
with all other indemnifying parties similarly notified, to assume the defense
thereof with counsel reasonably satisfactory to such indemnified party. Upon
receipt of notice from the indemnifying party to such indemnified party of its
election so to assume the defense of such action and approval by the indemnified
party of counsel, the indemnifying party will not be liable to such indemnified
party under this Section 3.03 for any legal or other expenses subsequently
incurred by such indemnified party in connection with the defense thereof unless
the indemnified party shall not have employed counsel reasonably satisfactory to
the indemnified party to represent the indemnified party within a reasonable
time after notice of commencement of action, in which case the reasonable fees
and expenses of counsel shall be at the expense of the indemnifying party, or
unless the indemnified party and the indemnifying party, in the reasonable
opinion of counsel to the indemnified party, have defenses distinct from, or
contradictory to, the defenses available to the other.

                  (iv) If the indemnification provided for in this Section 3.03
is required by its terms but is for any reason held to be unavailable to or
otherwise insufficient to hold harmless an indemnified party under paragraphs
(i) or (ii) of this Section 3.03 in respect to any losses, claims, damages,
liabilities or expenses referred to herein (subject to the limitation of
paragraph (iii) of this Section 3.03), then each applicable indemnifying party
shall contribute to the amount paid or payable by such indemnified party as a
result of any losses, claims, damages, liabilities or expenses referred to
herein (I) in such proportion as is appropriate to reflect the relative benefits
received by the Company and the Purchaser from the sale of the Common Stock
contemplated by this Agreement or (II) if the allocation provided by clause (I)


                                       20
<PAGE>

above is not permitted by applicable law, in such proportion as is appropriate
to reflect not only the relative benefits referred to in clause (I) above but
the relative fault of the Company and the Purchaser in connection with the
statements or omissions or inaccuracies in the representations and warranties in
this Agreement that resulted in such losses, claims, damages, liabilities or
expenses, as well as any other relevant equitable considerations. The relative
benefits received by the Company on the one hand and the Purchaser on the other
shall be deemed to be in the same proportion as the amount paid by the Purchaser
to the Company pursuant to this Agreement for the Shares purchased by the
Purchaser that were sold pursuant to the Registration Statement bears to the
difference (the "DIFFERENCE") between the amount such Purchaser paid for the
Shares that were sold pursuant to the Registration Statement and the amount
received by such Purchaser from such sale. The relative fault of the Company on
the one hand and the Purchaser on the other shall be determined by reference to,
among other things, whether the untrue or alleged statement of a material fact
or the omission or alleged omission to state a material fact or the inaccurate
or the alleged inaccurate representation and/or warranty relates to information
supplied by the Company or by the Purchaser and the parties' relative intent,
knowledge, access to information and opportunity to correct or prevent such
statement, omission or inaccuracy. The amount paid or payable by a party as a
result of the losses, claims, damages, liabilities and expenses referred to
above shall be deemed to include, subject to the limitations set forth in
paragraph (iii) of this Section 3.03, any legal or other fees or expenses
reasonably incurred by such party in connection with investigating or defending
any action or claim. The provisions set forth in paragraph (iii) of this Section
3.03 with respect to the notice of the threat or commencement of any threat or
action shall apply if a claim for contribution is to be made under this
paragraph (iv); provided, however, that no additional notice shall be required
with respect to any threat or action for which notice has been given under
paragraph (iii) for purposes of indemnification. The Company and each Purchaser
agree that it would not be just and equitable if contribution pursuant to this
Section 3.03 were determined solely by pro rata allocation or by any other
method of allocation which does not take account of the equitable considerations
referred to in this paragraph. Notwithstanding the provisions of this Section
3.03, the Purchaser shall not be required to contribute any amount in excess of
the amount by which the Difference exceeds the amount of any damages that such
Purchaser has otherwise been required to pay by reason of such untrue or alleged
untrue statement or omission or alleged omission. No person guilty of fraudulent
misrepresentation (within the meaning of Section 11(f) of the Securities Act)
shall be entitled to contribution from any person who was not guilty of such
fraudulent misrepresentation.


                                   ARTICLE IV

                              CONDITIONS TO CLOSING

         SECTION 4.01 CONDITIONS TO THE OBLIGATIONS OF THE PURCHASER. The
obligation of the Purchaser to purchase Shares at a Closing shall be subject to
the satisfaction of the following conditions, or the waiver of such conditions
by the Purchaser, at or prior to the applicable Closing:


                                       21
<PAGE>

                  (a) the representations and warranties of the Company set
forth in Section 2.01 of this Agreement shall be true and correct with the same
force and effect as though expressly made on and as of such Closing, except for
representations or warranties made as of a particular date which representations
and warranties shall be true and correct as of such date;

                  (b) the Company shall have complied with all the agreements
hereunder and satisfied all the conditions on its part to be performed or
satisfied hereunder at or prior to such Closing;

                  (c) the Company shall have delivered to the Purchaser a
certificate executed by the Chairman of the Board or Chief Executive Officer and
the chief financial or accounting officer of the Company, dated the applicable
Closing, to the effect that the conditions in clauses (i) and (ii) have been
satisfied;

                  (d) Procopio, Cory, Hargreaves & Savitch LLP, counsel to the
Company, shall have delivered to the Purchaser its legal opinion in form and
substance satisfactory to the Purchaser; and

                  (f) there shall not have been (i) any domestic or
international event of war or terrorism, that shall have materially and
adversely disrupted the U.S. securities markets; or (ii) a general suspension
of, or a general limitation on prices for, trading in securities on the New York
Stock Exchange or the American Stock Exchange or in the over-the-counter market;
or (iii) a banking moratorium declared by any state or federal authority; or
(iv) a moratorium in foreign exchange trading by major international banks or
persons declared; or (v) a material interruption in the mail service or other
means of communication within the United States; or (vi) a material or
substantial loss suffered by the Company by fire, flood, accident, hurricane,
earthquake, theft, sabotage, or other calamity or malicious act, whether or not
such loss shall have been insured, or from any labor dispute or court or
government action, order, or decree, which will, in the reasonable discretion of
the Purchaser, make it inadvisable to proceed with any portion of the
transactions contemplated hereby; or (viii) any material adverse change in the
business, prospects, financial condition, or results of operations of the
Company; or (ix) any material governmental restrictions shall have been imposed
on trading in securities in general, which restrictions are not in effect on the
date hereof; or (x) passed by the Congress of the United States or by any state
legislature any act or measure, or adopted by any governmental body or
authoritative accounting institute or board, or any governmental executive, any
orders, rules, or regulations, which the Purchaser reasonably believes likely to
have a material adverse effect on the business, financial condition, or
financial statements of the Company or any of the Subsidiary or the market for
the Common Stock.

         SECTION 4.02 CONDITIONS TO THE OBLIGATIONS OF THE COMPANY. The
obligation of the Company to sell Shares at any Closing shall be subject to the
satisfaction of the following conditions, or the waiver of such conditions by
the Company, at or prior to the applicable Closing:

                  (a) the representations and warranties of the Purchaser set
forth in Section 2.02 of this Agreement shall be true and correct with the same
force and effect as though expressly made on and as of such Closing, except for
representations or warranties made as of a particular date which representations
and warranties shall be true and correct as of such date;


                                       22
<PAGE>

                  (b) the Purchaser shall have complied with all the agreements
hereunder and satisfied all the conditions on its part to be performed or
satisfied hereunder at or prior to such Closing; and

                  (c) the Purchaser shall have delivered to the Company a
certificate executed by the Purchaser (or, if the Purchaser is a business
entity, by a duly authorized officer of the Purchaser), dated the applicable
Closing, to the effect that the conditions in clauses (a) and (b) have been
satisfied.

         SECTION 4.03 CONDITIONS TO THE OBLIGATIONS OF BOTH PARTIES WITH RESPECT
TO THE SECOND CLOSING. The obligation of the Company to sell, and the Purchaser
to purchase, Shares at the Second Closing shall be subject to the satisfaction
of the following additional condition:

                  (a) the Registration Statement shall have been declared by the
Commission, and shall not have been withdrawn, no stop order suspending the
effectiveness of the Registration Statement shall be in effect, and no
proceedings for the suspension of the effectiveness of the Registration
Statement shall have been instituted or threatened by the Commission.

                                    ARTICLE V

                                  MISCELLANEOUS

         SECTION 5.01 NOTICES. All notices, requests, consents and other
communications hereunder shall be in writing, shall be mailed by first-class
registered or certified airmail, confirmed facsimile or nationally recognized
overnight express courier postage prepaid, and shall be deemed given when so
mailed and shall be delivered as addressed as follows:

                  (a) if to the Company, to:

                      MicroIslet, Inc.
                      6370 Nancy Ridge Drive
                      Suite 112
                      San Diego, California  92121
                      Attention: Chief Executive Officer and Chief Financial
                         Officer

                      with a copy to:

                      Procopio, Cory, Hargreaves & Savitch LLP
                      530 B Street, Suite 2100
                      San Diego, California  92101
                      Attention:  John D. Tishler
                      Phone:  (619) 515-3258
                      Facsimile:  (619) 235-0398


                                       23
<PAGE>

                      or to such other person at such other place as the Company
                      shall designate to the Purchaser in writing; and

                  (b) if to the Purchaser, at the address set forth below the
         Purchaser's signature to this Agreement.

         SECTION 5.02 ASSIGNMENT. Neither party hereto may assign or delegate
any of such party's rights or obligations under or in connection with this
Agreement, and any attempted assignment or delegation of such rights or
obligations shall be void. Except as expressly provided in Section 3.03 with
respect to Purchaser Affiliates, directors and controlling persons of the
Company and officers of the Company who signed the Registration Statement, no
person, including without limitation any person who purchases or otherwise
acquires or receives any Shares from the Purchaser, is an intended third party
beneficiary of this Agreement, and no party to this Agreement shall have any
obligation arising under this Agreement to any person other than the other party
hereto and, to the extent expressly provided in Section 3.03, Purchaser
Affiliates, directors and controlling persons of the Company and officers of the
Company who signed the Registration Statement.

         SECTION 5.03 CHANGES. This Agreement may not be modified or amended
except pursuant to an instrument in writing signed by the Company and the
Purchaser.

         SECTION 5.04 HEADINGS. The headings of the various sections of this
Agreement have been inserted for convenience of reference only and shall not be
deemed to be part of this Agreement.

         SECTION 5.05 SEVERABILITY. In case any provision contained in this
Agreement should be invalid, illegal or unenforceable in any respect, the
validity, legality and enforceability of the remaining provisions contained
herein shall not in any way be affected or impaired thereby.

         SECTION 5.06 GOVERNING LAW; VENUE. This Agreement shall be governed by
and construed in accordance with the laws of the State of California, without
regard to its conflicts of law principles, and the federal law of the United
States of America. The Company irrevocably consents to the jurisdiction of the
courts of the State of California and of any federal court, in each case located
in San Diego, California in connection with any action or proceeding arising out
of, or relating to, this Agreement, any document or instrument delivered
pursuant to, in connection with, or simultaneously with this Agreement, or a
breach of this Agreement or any such document or instrument. In any such action
or proceeding, the Company waives personal service of any summons, complaint, or
other process and agrees that service thereof may be made in accordance with
Section 5.01. Within 30 days after such service, or such other time as may be
mutually agreed upon in writing by the attorneys for the parties to such action
or proceeding, the Company shall appear or answer such summons, complaint, or
other process. Should the Company fail to appear or answer within such 30-day
period or such extended period, as the case may be, the Company shall be deemed
in default and judgment may be entered against the Company for the amount as
demanded in any summons, complaint, or other process so served.


                                       24
<PAGE>

         SECTION 5.07 COUNTERPARTS. This Agreement may be executed in two or
more counterparts, each of which shall constitute an original, but all of which,
when taken together, shall constitute but one instrument, and shall become
effective when one or more counterparts have been signed by each party hereto
and delivered to the other parties.




                                       25
<PAGE>


         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
executed by their duly authorized representatives as of the day and year first
above written.

                                        "COMPANY":

                                        MICROISLET, INC.



                                        BY: /s/ John F. Steel IV
                                            ------------------------------------
                                            NAME: JOHN F. STEEL IV
                                            TITLE:  CHIEF EXECUTIVE OFFICER


                                        "PURCHASER":



                                        ----------------------------------------
                                        PRINT NAME:

                                        ADDRESS:

                                        ----------------------------------------

                                        ----------------------------------------
                                        Phone:
                                               ---------------------------------
                                        Fax:
                                             -----------------------------------




                                       26
<PAGE>



                                SCHEDULE 1.01(a)

                                    TRANCHES
                                    --------


<TABLE>
<CAPTION>

                    NUMBER OF SHARES       TRANCHE PURCHASE PRICE PER   NUMBER OF     EXERCISE
   TRANCHE         INCLUDED IN TRANCHE    TRANCHE SHARE (U.S. DOLLARS)   WARRANTS      PRICE
   -------         -------------------    ----------------------------   --------      -----

<S>                                                   <C>                                  <C>
First Tranche                                         $1.30                                $1.00
Second Tranche                                        $1.50                                $1.30
--------------         ------------                                      -------
    Total

</TABLE>






                                Schedule 1.01(a)