Exhibit 10.330

|CONFIDENTIAL |  | REDACTED VERSION
|------------ |  | ----------------

[***] CERTAIN INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN
REQUESTED WITH RESPECT TO THE OMITTED PORTIONS.

TERM SHEET

This
binding Term Sheet sets forth the agreement of Chiron Corporation ("Chiron"), on the one hand, and F. Hoffmann-La Roche Ltd. and Roche Molecular
Systems, Inc. (collectively, "Roche"), on the other, with respect to the settlement of their current arbitration relating to royalties ("Arbitration"), through amendment of the HIV Probe
License Agreement by and between the parties effective as of October 10, 2000 ("Clinical Diagnostics Agreement") and the Blood Screening HIV Probe License Agreement by and between the parties
effective as of January 1, 2001 ("Blood Screening Agreement," collectively with the Clinical Diagnostics Agreement, the "Agreements"). Terms not defined in this Term Sheet have the meanings
given to them in the applicable Agreement. This Term Sheet shall become effective as of September 3, 2004.



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8.            a.[***].



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|AGREED TO AND ACCEPTED BY:    |  |                         
|----------------------------- |  | ------------------------
|Chiron Corporation            |  |                         
|By:                           |  | /s/JEKENT               
|                              |  |                         
|Date:                         |  | Sept. 3, 2004           
|                              |  |                         
|AGREED TO AND ACCEPTED BY:    |  |                         
|F. Hoffmann-La Roche Ltd.     |  |                         
|By:                           |  | /s/HEINO VON PRONDZYNSKI
|                              |  |                         
|                              |  | /s/ROBERT YATES         
|                              |  |                         
|Date:                         |  | 3 Sept 04               
|                              |  |                         
|AGREED TO AND ACCEPTED BY:    |  |                         
|Roche Molecular Systems, Inc. |  |                         
|By:                           |  | /s/H. DREISMANN         
|                              |  |                         
|Date:                         |  | September 3, 2004       
|                              |  |                         

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|CONFIDENTIAL |  | REDACTED VERSION
|------------ |  | ----------------

EXHIBIT A

BEFORE THE HONORABLE
CHARLES B. RENFREW, ARBITRATOR

|IN THE MATTER OF THE ARBITRATION
  
BETWEEN
  
CHIRON CORPORATION, |  |                             
|------------------------------------------------------------------ |  | ----------------------------
|Claimant                                                           |  | STIPULATED ARBITRATION AWARD
|AND
 
ROCHE MOLECULAR SYSTEMS, INC.,                               |  |                             
|Respondent                                                         |  |                             

Stipulation

Chiron
Corporation and Roche Molecular Systems, Inc., on behalf of themselves and their affiliates, hereby irrevocably stipulate as follows:

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|Date: August    , 2004 |  | Agreed:                                                                                                                                               | 
|---------------------- |  | ----------------------------------------------------------------------------------------------------------------------------------------------------- | 
|                       |  |                                                                                                                                                       | 
|                       |  | Stephen S. Rabinowitz
FRIED, FRANK, HARRIS, SHRIVER & JACOBSON LLP                                                                                   
|                       |  | Charles B. Cohler
PAUL, HASTINGS, JANOFSKY & WALKER LLP
  
Attorneys for Roche Molecular Systems, Inc.                                               
|Date: August    , 2004 |  | Agreed:                                                                                                                                               | 
|                       |  |                                                                                                                                                       | 
|                       |  | Rachel Krevans
Mathew I. Kreeger
Wesley E. Overson
Lawrence B. Berroya
Peter P. Meringolo
MORRISON & FOERSTER LLP
  
Attorneys for Chiron Corporation

|IT IS SO ORDERED. |  |                                    
|----------------- |  | -----------------------------------
|By:               |  |                                    
|                  |  | Hon. Charles B. Renfrew, Arbitrator
|Date:             |  |                                    
|                  |  |                                    

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|CONFIDENTIAL |  | REDACTED VERSION
|------------ |  | ----------------

EXHIBIT B

BEFORE THE HONORABLE
CHARLES B. RENFREW, ARBITRATOR

|IN THE MATTER OF THE ARBITRATION
  
BETWEEN
  
CHIRON CORPORATION, |  |                                                 
|------------------------------------------------------------------ |  | ------------------------------------------------
|Claimant                                                           |  | RENEWED STIPULATED RE DELAYED RENDERING OF AWARD
|AND
 
ROCHE MOLECULAR SYSTEMS, INC.,                               |  |                                                 
|Respondent                                                         |  |                                                 

Stipulation

Chiron Corporation and Roche Molecular Systems, Inc., on behalf of themselves and their affiliates, jointly agree and stipulate as follows:

Notwithstanding
Section 9(d)(12) of Settlement Agreement by and between the parties effective as of October 10, 2000, which requires that the Arbitrator render an award in
this Arbitration together with a decision on the award in writing ("Award") within seven calendar days following the submission

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of
post-hearing briefs, the parties jointly request that the Arbitrator not render the Award prior to September 14, 2004, at 4:00 p.m.

|Date: August    , 2004 |  | Agreed:                                                                                                                                               | 
|---------------------- |  | ----------------------------------------------------------------------------------------------------------------------------------------------------- | 
|                       |  |                                                                                                                                                       | 
|                       |  | Stephen S. Rabinowitz
FRIED, FRANK, HARRIS, SHRIVER & JACOBSON LLP                                                                                   
|                       |  | Charles B. Cohler
PAUL, HASTINGS, JANOFSKY & WALKER LLP
  
Attorneys for Roche Molecular Systems, Inc.                                               
|Date: August    , 2004 |  | Agreed:                                                                                                                                               | 
|                       |  |                                                                                                                                                       | 
|                       |  | Rachel Krevans
Mathew I. Kreeger
Wesley E. Overson
Lawrence B. Berroya
Peter P. Meringolo
MORRISON & FOERSTER LLP
  
Attorneys for Chiron Corporation

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|CONFIDENTIAL |  | REDACTED VERSION
|------------ |  | ----------------

EXHIBIT C    REFUND SCHEDULE AND ADJUSTED ROYALTY RATES

|Refund Request Date |  | Refund
Amount:
Clinical
Diagnostics
(MM) |  | Refund
Amount:
Blood
Screening
(MM) |  | Clinical
Diagnostics
Earned
Royalty
Rate |  | Minimum
Amount/Test:
HIV
Qualitative
Assay |  | Minimum
Amount/Test:
HIV
Quantitative
Assay |  | Earned
Royalty
Amount:
Blood
Screening |  | Earned
Royalty
Amount:
Plasma
Fractation
|------------------- |  | ---------------------------------------- |  | ----------------------------------- |  | ---------------------------------------- |  | ------------------------------------------ |  | ------------------------------------------- |  | -------------------------------------- |  | ----------------------------------------
|2/1/05              |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   
|3/31/05             |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   
|6/30/05             |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   
|9/30/05             |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   
|12/31/05            |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   
|3/31/06             |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   
|6/30/06             |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   
|10/2/06             |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   
|12/31/06            |  | [***]                                    |  | [***]                               |  | [***]                                    |  | [***]                                      |  | [***]                                       |  | [***]                                  |  | [***]                                   

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