Federal Register / Vol. 72, No. 19 / Tuesday, January 30, 2007 / Notices 4285 

National Institutes of Health, 6011 

Executive Boulevard, Suite 325, 

Rockville, MD 20852–3804; E-mail: 

ThalhamC@mail.nih.gov; Telephone: 

301–435–4507; Facsimile: 301–402–

0220. 

SUPPLEMENTARY INFORMATION: The 

prospective co-exclusive license will be 

royalty bearing and will comply with 

the terms and conditions of 35 U.S.C. 

209 and 37 CFR 404.7. The prospective 

exclusive license may be granted unless, 

within 60 days from the date of this 

published Notice, NIH receives written 

evidence and argument that establishes 

that the grant of the license would not 

be consistent with the requirements of 

35 U.S.C. 209 and 37 CFR 404.7. 

The technology described and 

claimed in the subject invention relates 

to methods to enhance and prolong the 

body’s immune response as well as to 

promote targeted tissue damage, such as 

for tumor destruction, by inhibiting 

signaling through the adenosine 

receptor. The inventors have shown that 

adenosine A2a and A3a receptors play 

a critical and non-redundant role in 

down-regulation of inflammation in 

vivo by acting as the physiological 

termination mechanism that can limit 

the immune response. The methods 

described involve administering either 

an adenosine-degrading drug or an 

adenosine receptor antagonist to exert a 

more effective and durable immune 

response and inflammation, and more 

specifically to the subject exclusive 

license application, to reduce the size of 

tumors. Furthermore, using the claimed 

method in combination with 

conventional anti tumor agent can be an 

effective treatment against cancer. 

The invention has potential 

applications in the many markets in 

which therapeutic and preventive uses 

of manipulating the adenosine pathway 

are involved, including the regulation of 

hypoxia, tissue damage, tumor 

destruction, inflammation, increasing 

the efficacy of vaccines, and other 

immune responses. 

This invention is further described in 

Ohta A et al., ‘‘Role of G-proteincoupled adenosine receptors in downregulation of inflammation and 

protection from tissue damage,’’ Nature 

2001 Dec 20–27; 414(6866):916–20. 

The field of use may be limited to 

‘‘Prevention and treatment of human 

cancer and tumors by inhibitors of any 

or all of the adenosine receptor subtypes 

covered by the Licensed Patent Rights’’. 

Properly filed competing applications 

for a license filed in response to this 

notice will be treated as objections to 

the contemplated license. Comments 

and objections submitted in response to 

this notice will not be made available 

for public inspection, and, to the extent 

permitted by law, will not be released 

under the Freedom of Information Act, 

5 U.S.C. 552. 

This announcement is a supplement 

to the one published in the Federal 

Register on April 11, 2005 (70 FR 

18419). 

Dated: January 18, 2007. 

Steven M. Ferguson, 

Director, Division of Technology Development 

and Transfer, Office of Technology Transfer, 

National Institutes of Health. 

[FR Doc. E7–1376 Filed 1–29–07; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

Privacy Office; Published Privacy 

Impact Assessments on the Web 

AGENCY: Privacy Office, Office of the 

Secretary, Department of Homeland 

Security. 

ACTION: Notice of Publication of Privacy 

Impact Assessments. 

SUMMARY: The Privacy Office of the 

Department of Homeland Security is 

making available four Privacy Impact 

Assessments on various programs and 

systems in the Department. These 

assessments were approved and 

published on the Privacy Office’s Web 

site between December 1, 2006 and 

December 31, 2006. 

DATES: The Privacy Impact Assessments 

will be available on the DHS Web site 

until April 2, 2007, after which they 

may be obtained by contacting the DHS 

Privacy Office (contact information 

below). 

FOR FURTHER INFORMATION CONTACT: 

Hugo Teufel III, Chief Privacy Officer, 

Department of Homeland Security, 

Washington, DC 20528; by telephone 

(571) 227–3813, facsimile (866) 466–

5370, or e-mail: pia@dhs.gov. 

SUPPLEMENTARY INFORMATION: Between 

December 1, 2006 and December 31, 

2006, the Chief Privacy Officer of the 

Department of Homeland Security 

(DHS) approved and published four 

Privacy Impact Assessments (PIAs) on 

the DHS Privacy Office Web site, 

http://www.dhs.gov/privacy, under the 

link for ‘‘Privacy Impact Assessments.’’

Below is a short summary of each of 

those systems, indicating the DHS 

component responsible for the system, 

and the date on which the PIA was 

approved. Additional information can 

be found on the Web site or by 

contacting the Privacy Office. 

1. System: DisasterHelp.gov. 

Component: Science and Technology. 

Date of approval: December 19, 2006. 

The DisasterHelp.Gov (DHelp) Web 

site or Web portal is operated by the 

Science and Technology Directorate of 

the Department of Homeland Security. It 

is intended to assist political and civil 

service leadership, emergency 

managers, homeland security advisors, 

and first responders in the execution of 

their disaster management 

responsibilities. The information on this 

Web site will be used to enhance 

disaster management on an interagency 

and intergovernmental basis by helping 

users find information and services. The 

types of personally identifiable 

information used will include contact 

information for these individuals. The 

collection of this personally identifiable 

information is the reason for this 

privacy impact assessment. 

2. System: Alien Flight Student 

Program (Amended). 

Component: Transportation Security 

Administration. 

Date of approval: December 22, 2006. 

The Transportation Security 

Administration (TSA) will collect 

personal information about flighttraining candidates to conduct the 

security threat assessments on alien 

flight students required by the Aviation 

and Transportation Security Act and 

section 612 of Vision 100—Century of 

Aviation Reauthorization Act. For pilots 

seeking recurrent training, the Alien 

Flight Student Program will verify 

eligibility for such training. TSA is 

amending the PIA originally published 

in June 2004 to reflect certain updates 

after periodic review, including its use 

of commercial data for identity 

verification purposes, and the 

promulgation of an applicable record 

retention schedule. 

3. System: Threat Assessment for 

Airport Badge and Credential Holders. 

Component: Transportation Security 

Administration. 

Date of approval: December 20, 2006. 

TSA is amending the PIA for the 

Security Threat Assessment for Airport 

Badge and Credential Holders to reflect 

an expansion of the covered population. 

Recently amended airport security 

directives now require that each 

individual to whom an airport issues an 

identification badge or credentials 

undergo a security threat assessment 

regardless of the level of unescorted 

access permitted the individual. Namebased security threat assessments will 

be performed on all individuals seeking 

or holding airport identification badges 

or credentials. Fingerprint-based 

criminal history checks, in addition to 

the name-based security threat 

assessments, will continue to be 


ycherry on PROD1PC64 with NOTICES
4286 Federal Register / Vol. 72, No. 19 / Tuesday, January 30, 2007 / Notices 

required for those individuals seeking 

access to the Security Identification 

Area or Sterile Area. TSA is amending 

this PIA to reflect the amended 

requirements. 

4. System: Transportation Worker 

Identification Credential Program Final 

Rule. 

Component: Transportation Security 

Administration. 

Date of approval: December 29, 2006. 

TSA is publishing a joint Final Rule 

with the United States Coast Guard to 

implement the Transportation Worker 

Identification Credential (TWIC) 

program to provide a biometric 

credential that can be used to confirm 

the identity of workers in the national 

transportation system. For each person 

subject to the program, TSA will 

conduct a security threat assessment 

before issuing the credential. TSA will 

collect identifying information, 

supporting documentation, a digital 

photograph, and fingerprints, as more 

fully set forth in section 1.1 of the PIA. 

The PIA reflects the TWIC Program as 

set out in the Final Rule and follows on 

the PIA for the TWIC Prototype, which 

was published at http://www.dhs.gov on 

November 5, 2004, and the PIA for the 

Notice of Proposed Rulemaking 

(NPRM), which was published at 

http://www.dhs.gov on May 9, 2006. The 

updated PIA reflects changes made to 

the TWIC program in response to public 

comment on the NPRM and lessons 

learned from the TWIC Prototype. 

Dated: January 24, 2007. 

Hugo Teufel III, 

Chief Privacy Officer. 

[FR Doc. 07–388 Filed 1–29–07; 8:45 am] 

BILLING CODE 4410–10–P 

DEPARTMENT OF HOMELAND 

SECURITY 

Bureau of Customs and Border 

Protection 

[Docket No. USCBP–2007–0003] 

Notice of Meeting of the Departmental 

Advisory Committee on Commercial 

Operations of Customs and Border 

Protection and Related Homeland 

Security Functions (COAC) 

AGENCY: U.S. Customs and Border 

Protection, Department of Homeland 

Security (DHS). 

ACTION: Notice of Federal Advisory 

Committee Meeting. 

SUMMARY: The Departmental Advisory 

Committee on Commercial Operations 

of U.S. Customs and Border Protection 

and Related Homeland Security 

Functions (popularly known as 

‘‘COAC’’) will meet on February 14, 

2007 in Washington, DC. The meeting 

will be open to the public. 

DATES: COAC will meet Wednesday, 

February 14th from 9 a.m. to 1 p.m. 

Please note that the meeting may close 

early if the committee has completed it 

business. 

ADDRESSES: The meeting will be held at 

the Ronald Reagan Building in the 

Rotunda Ballroom, 1300 Pennsylvania 

Avenue, NW., Washington, DC 20004. 

Written material, comments, and 

requests to make oral presentations at 

the meeting should reach the contact 

person listed below by February 1st. 

Requests to have a copy of your material 

distributed to each member of the 

committee prior to the meeting should 

reach the contact person at the address 

below by February 7, 2007. Comments 

must be identified by USCBP–2007–

0003 and may be submitted by one of 

the following methods: 

• Federal eRulemaking Portal: http:// 

www.regulations.gov. Follow the 

instructions for submitting comments. 

• E-mail: traderelations@dhs.gov. 

Include the docket number in the 

subject line of the message. 

• Fax: 202–344–1969. 

• Mail: Ms. Wanda Tate, Office of 

International Affairs and Trade 

Relations, U.S. Customs and Border 

Protection, Department of Homeland 

Security, Room 2.4B, Washington, DC 

20229. 

Instructions: All submissions received 

must include the words ‘‘Department of 

Homeland Security’’ and the docket 

number for this action. Comments 

received will be posted without 

alteration at www.regulations.gov, 

including any personal information 

provided. 

Docket: For access to the docket to 

read background documents or 

comments received by the COAC, go to 

http://www.regulations.gov. 

FOR FURTHER INFORMATION CONTACT: Ms. 

Wanda Tate, Office of International 

Affairs and Trade Relations, Customs 

and Border Protection, Department of 

Homeland Security, 1300 Pennsylvania 

Ave., NW., Room 2.4B, Washington, DC 

20229; traderelations@dhs.gov; 

telephone 202–344–1440; facsimile 

202–344–1969. 

SUPPLEMENTARY INFORMATION: Notice of 

this meeting is given under the Federal 

Advisory Committee Act, 5 U.S.C. App. 

2 (Pub. L. 92–463). The Departmental 

Advisory Committee on Commercial 

Operations of U.S. Customs and Border 

Protection and Related Homeland 

Security Functions (COAC) is tasked 

with providing advice to the Secretary 

of Homeland Security, the Secretary of 

the Treasury, and the Commissioner of 

Customs and Border Protection (CBP) on 

matters pertaining to the commercial 

operations of CBP and related functions 

within DHS or the Department of the 

Treasury. 

The first meeting of the tenth term of 

COAC will be held at the date, time and 

location specified above. A tentative 

agenda for the meeting is set forth 

below. 

Tentative Agenda 

1. Introduction of the newlyappointed tenth term COAC members. 

2. Collection of additional data 

elements for cargo security. 

3. Trade Resumption. 

4. International Container Security. 

5. CSI (Container Security Initiative). 

6. C–TPAT (Customs-Trade 

Partnership Against Terrorism). 

7. Office of International Trade. 

8. Export Enforcement—training and 

policy. 

Procedural 

This meeting is open to the public. 

Please note that the meeting may close 

early if all business is finished. 

Participation in COAC deliberations is 

limited to committee members, 

Department of Homeland Security 

officials, and persons invited to attend 

the meeting for special presentations. 

All visitors to the Ronald Reagan 

Building will have to go through a 

security checkpoint to be admitted to 

the building. Since seating is limited, all 

persons attending this meeting should 

provide notice, preferably by close of 

business Monday, February 12, 2007, to 

Ms. Wanda Tate, Office of Trade 

Relations, U.S. Customs and Border 

Protection, Department of Homeland 

Security, Washington, DC 20229, 

telephone 202–344–1440; facsimile 

202–344–1969. 

Information on Services for Individuals 

With Disabilities 

For information on facilities or 

services for individuals with disabilities 

or to request special assistance at the 

meeting, contact Ms. Wanda Tate as 

soon as possible. 

Dated: January 26, 2007. 

Michael C. Mullen, 

Assistant Commissioner, Office of 

International Affairs and Trade Relations, 

Customs and Border Protection. 

[FR Doc. E7–1515 Filed 1–29–07; 8:45 am] 

BILLING CODE 9111–14–P 


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