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| Current Bibliographies in Medicine                                                    |
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# Current Bibliographies in Medicine 2000-6

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# Adjuvant Therapy for Breast Cancer

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| **Table of Contents**Series NotePDF Version of This CBMSample CitationsIntroduction**Bibliography**:
1. Controversies and Prospects

2. Factors Used to Select Adjuvant Therapy
- Tumor-Related Factors
- Patient-Related Factors

3. Adjuvant Hormonal Therapy
- Tamoxifen
- Other

4. Adjuvant Chemotherapy
- Indications
- Specific Regimens
- Pre-Operative Approaches
- Dose-Intense Approaches

5. Post-Mastectomy Adjuvant Radiotherapy

6. Treatment-Related Side Effects and Quality of Life Issues
- Overviews
- Tamoxifen
- Chemotherapy
- Decision-Making Analyses

*Return to the top* | January 1995 through July 2000, plus selected earlier citations

2230 Citations

Prepared byAnne Maria Baxter, M.L.S., National Library of MedicineJeffrey S. Abrams, M.D., National Cancer Institute

2000 September

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICESPublic Health ServiceNational Institutes of Health

National Library of MedicineReference Section8600 Rockville PikeBethesda, Maryland 20894

**Series Note**

Each bibliography in the Current Bibliographies in Medicine (CBM) series covers a distinct subject area of biomedicine and is intended to fulfill a current awareness function. Citations are usually derived from searching a variety of online databases. NLM databases utilized include MEDLINE®, BIOETHICSLINE®, HEALTHSTARTM, LocatorPlus® , POPLINETM, PubMed®, and TOXLINE®. The only criterion for the inclusion of a particular published work is its relevance to the topic being presented; the format, ownership, or location of the material is not considered.

Publications in the *Current Bibliographies in Medicine* series are available at no cost to anyone with Internet access through the Library's World Wide Web site at http://www.nlm.nih.gov/pubs/resources.html.

Comments and suggestions on this series may be addressed to:

Karen Patrias, EditorCurrent Bibliographies in MedicineReference SectionNational Library of MedicineBethesda, MD 20894Phone: 301-496-6097Fax: 301-402-1384Internet: ref@nlm.nih.gov

**PubMed® and Internet Grateful Med®**

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For those users without access to the World Wide Web, please contact the Library's Customer Service Desk at 1-888-FINDNLM (301-594-5983 international) or e-mail custserv@nlm.nih.gov for information on alternative ways to search.

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**PDF Version of This CBM**

Beginning with the 2000 CBMs, two formats are offered: HyperText Markup Language (HTML) and Portable Document Format (PDF). PDF documents require the use of the Adobe® Acrobat® Reader, which can be downloaded from Adobe's Web site at no charge.

The PDF version of this CBM can be downloaded directly from http://www.nlm.nih.gov/pubs/cbm/adjuvant_therapy_breast_cancer.pdf.

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**Sample Citations**

Citations are formatted according to the rules established for *Index Medicus*®*****. Sample journal and monograph citations appear below. For journal articles written in a foreign language, the English translation of the title is placed in brackets; for monographs, the title is given in the original language. In both cases the language of publication is shown by a three letter abbreviation appearing at the end of the citation.

Note also for journal articles that an availability statement follows many citations. This statement contains the Internet address for the citation in the NLM PubMed® retrieval system. The PubMed record includes an abstract for most articles and may also provide a link to the publisher's Internet site.

**Journal Article:**

*Example:*Bellet M, Alonso C, Ojeda B. Breast cancer in the elderly. Postgrad Med J 1995 Nov;71(841):658-64. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7494769&dopt=Abstract

*Order, with separating punctuation:*Authors. Article Title. Abbreviated Journal Title Date;Volume(Issue):Pages. Availability.

**Meeting Abstracts:**

*Example:*Weber B, Luporsi. Effects of breast cancer adjuvant chemotherapy on menstrual function [abstract]. Breast Cancer Res Treat 1996;37 Suppl:78.

*Order, with separating punctuation:*Authors. Title [Abstract Indicator]. Abbreviated Journal Title Date;Volume(Issue):Pages.

***** For details of the formats used for references, see the following publication:Patrias, Karen. *National Library of Medicine recommended formats for bibliographic citation*. Bethesda (MD): The Library; 1991 Apr. Available from: NTIS, Springfield, VA; PB91-182030.

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**Introduction**

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Adjuvant Therapy for Breast Cancer

Each year, more than 180,000 women in the United States are diagnosed with breast cancer, the most common type of cancer among women in this country. If current breast cancer rates stay constant, a female born today has a 1 in 8 chance of developing breast cancer sometime during her life. Through continuing research into new treatment methods, women with breast cancer now have more treatment options and hope for survival than ever before.

Studies have shown that adjuvant therapy - -treatment to kill cancer cells that may have begun to spread, or metastasize, from the breast tumor- - given in addition to surgery or other primary therapies increases a woman's chance of long-term survival. Two types of systemic adjuvant therapy are used for breast cancer, either alone or in combination: adjuvant chemotherapy involves a combination of anticancer drugs; adjuvant hormone therapy deprives cancer cells of the female hormone estrogen, which some breast cancer cells need to grow. In addition to these systemic therapies, radiation therapy is sometimes used as a local adjuvant treatment to help destroy breast cancer cells that have spread to nearby parts of the body. The rapid pace of discovery in this area continues to broaden the knowledge base from which informed treatment decisions can be made.

This bibliography was prepared for the National Institutes of Health Consensus Development Conference on Adjuvant Therapy for Breast Cancer held November 1-3, 2000 in Bethesda, Maryland. The purpose of this Conference was to clarify for clinicians, patients, and the general public the various issues regarding the use of adjuvant therapy for breast cancer. The consensus development panel addressed the following key questions:
      - Which factors should be used to select systemic adjuvant therapy?
      - For which patients should adjuvant hormonal therapy be recommended?
      - For which patients should adjuvant chemotherapy be recommended? Which agents should be used and at what dose or schedule?
      - For which patients should postmastectomy radiotherapy be recommended?
      - How do side effects and quality-of-life issues factor into individual decision-making about adjuvant therapy?
      - What are promising new research directions for adjuvant therapy?

The bibliography is intended to support the Conference agenda and to enhance the information presented at the Conference for the panelists and for the participants. It is not, however, intended to be all-inclusive; the topics were restricted to those being reviewed by the Conference panel. Therefore, the search was limited to human subjects research involving treatment, diagnostic testing, and other studies involving adjuvant therapy of breast cancer. Original journal articles, review articles, conference proceedings, meeting abstracts, letters to the editor, and editorials in the English language were included. Publications in languages other than English were excluded. The search time frame included references published primarily between 1995-2000, although a few earlier citations were also selected. Citations are arranged by subject reflecting the topics being covered by the panel. Within each subject the citations are arranged alphabetically by author. A citation appears in only one category.

The following bibliographies on breast cancer, produced for earlier NIH Conferences, may also be useful:

Baxter, Anne Maria; Patrias, Karen; Browne, Doris; Glover, Claudia; Hunter, Carrie P.; Kaur, Judith Salmon; Oglivie, Claudia; Romilly-Harper, A. Pat, compilers. Multicultural aspects of breast cancer etiology [bibliography]. Bethesda (MD): National Library of Medicine (US); 1999. (Current bibliographies in medicine; no. 99-1). 1430 citations from January 1993 through December 1998, plus selected earlier citations.

Hunt, Jennie P.; Gohagan, John K., compilers. Breast cancer screening in women ages 40-49 [bibliography]. Bethesda (MD): National Library of Medicine (US); 1996. (Current bibliographies in medicine; no. 96-05). 334 selected citations from January 1985 through November 1996.

Miller, Naomi; Dorr, F. Andrew, compilers. Treatment of early-stage breast cancer [bibliography]. Bethesda (MD): National Library of Medicine (US); 1990. (Current bibliographies in medicine; no. 90-06). 668 citations from January 1985 through May 1990.

Kenton, Charlotte. Adjuvant chemotherapy for breast cancer [bibliography]. Bethesda (MD): National Library of Medicine (US); 1985. (Literature search; no. 85-14). 403 citations from January 1980 through August 1985.

This publication is not copyrighted and may be freely reproduced. However any reproduction of this bibliography, in whole or in part, must include all credits. If you wish to cite this bibliography, the correct format is:

Baxter, Anne Maria; Abrams, Jeffrey S., compilers. Adjuvant therapy for breast cancer [bibliography]. Bethesda (MD): National Library of Medicine (US); 2000 Sep. 140 p. (Current bibliographies in medicine; no. 2000-6). 2230 citations from January 1995 through July 2000, plus selected earlier citations.

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## 1. Controversies and Prospects

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Aikin JL. Breast cancer research: past, present and future. J Gynecol Oncol Nurs 1997 Winter;7(1):23-7.

Ampil FL, Burton GV, Li BD, Mills GM. Radiotherapy with and without chemotherapy after breast conservation surgery for early stage breast cancer: a review of timing. Eur J Gynaecol Oncol 1999;20(4):254-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10475116&dopt;=Abstract

Anelli A, Ayala SR, Krutman P, Altino J, Markus SN. Importance of treatment sequence in patients receiving CMF and radiotherapy as adjuvant therapy for breast cancer [abstract]. Breast Cancer Res Treat 1999;57(1):48.

Antoine EC, Khayat D. Dose intensification and breast cancer: current results and future perspectives. Ann Oncol 1996;7 Suppl 2:31-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8805947&dopt;=Abstract

Aslani A, Begbie SD, Smith RC, Allen BJ, Levi JA, Bell DR, Wheeler HR. Do measurements of total body nitrogen (tbn) have a role in chemotherapy (c/t) dosing for breast cancer? [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A192.

Bajetta E, Celio L, Buzzoni R, Bichisao E. Novel non-steroidal aromatase inhibitors: are there new perspectives in the treatment of breast cancer? Tumori 1996 Sep-Oct;82(5):417-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9063515&dopt;=Abstract

Baum M, Benson JR. Current and future roles of adjuvant endocrine therapy in the management of early carcinoma of the breast. Recent Results Cancer Res 1996;140:215-26. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8787064&dopt;=Abstract

Bellet M, Alonso C, Ojeda B. Breast cancer in the elderly. Postgrad Med J 1995 Nov;71(841):658-64. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7494769&dopt;=Abstract

Bergh J. Time for integration of predictive factors for selection of breast cancer patients who need postoperative radiation therapy? [editorial]. J Natl Cancer Inst 1997 May 7;89(9):605-7. Comment on: J Natl Cancer Inst 1997 May 7;89(9):639-45. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9150179&dopt;=Abstract

Bertelli G, Venturini M, Del Mastro L, Garrone O, Cosso M, Gustavino C, Cusimano E, Guido T, Nicolo G, Rosso R. Tamoxifen and the endometrium: findings of pelvic ultrasound examination and endometrial biopsy in asymptomatic breast cancer patients. Breast Cancer Res Treat 1998 Jan;47(1):41-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9493974&dopt;=Abstract

Bonadonna G. Current and future trends in the multidisciplinary approach for high-risk breast cancer. The experience of the Milan Cancer Institute. Eur J Cancer 1996 Feb;32A(2):209-14. Comment in: Eur J Cancer 1997 Jan;33(1):164-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8664029&dopt;=Abstract

Bonadonna G. Future developments for paclitaxel in the treatment of breast cancer. Semin Oncol 1996 Feb;23(1 Suppl 1):65-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8629041&dopt;=Abstract

Bonadonna G. Future developments in adjuvant systemic therapy for high-risk breast cancer. Recent Results Cancer Res 1996;140:227-34. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8787065&dopt;=Abstract

Bonadonna G, Zambetti M, Valagussa P. Sequential or alternating doxorubicin and CMF regimens in breast cancer with more than three positive nodes. Ten-year results. JAMA 1995 Feb 15;273(7):542-7. Comment in: JAMA 1995 Sep 13;274(10):796-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7837388&dopt;=Abstract

Borner M, Bacchi M, Goldhirsch A, Greiner R, Harder F, Castiglione M, Jungi WF, Thurlimann B, Cavalli F, Obrecht JP, et al. First isolated locoregional recurrence following mastectomy for breast cancer: results of a phase III multicenter study comparing systemic treatment with observation after excision and radiation. Swiss group for clinical cancer research. J Clin Oncol 1994;12(10):2071-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7931476&dopt;=Abstract

Brenin DR, Morrow M. Breast-conserving surgery in the neoadjuvant setting. Semin Oncol 1998 Apr;25(2 Suppl 3):13-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9566202&dopt;=Abstract

Brockstein BE, Williams SF. High-dose chemotherapy with autologous stem cell rescue for breast cancer: yesterday, today and tomorrow. Stem Cells 1996 Jan;14(1):79-89. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8820954&dopt;=Abstract

Buchholz TA, Hunt KK, Amosson CM, Tucker SL, Strom EA, McNeese MD, Buzdar AU, Singletary SE, Hortobagyi GN. Sequencing of chemotherapy and radiation in lymph node-negative breast cancer. Cancer J Sci Am 1999;5(3):159-64. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10367172&dopt;=Abstract

Buzdar AU, Kau SW, Smith TL, Ames F, Singletary E, Strom E, McNeese M, Hortobagyi GN. The order of administration of chemotherapy and radiation and its effect on the local control of operable breast cancer. Cancer 1993;71(11):3680-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8490917&dopt;=Abstract

Byers T, Cyran L, Davis K, Prindiville S. Controversies in cancer care: hormone replacement therapy after breast cancer: how shall we do no harm? Cancer Pract 1998 Sep-Oct;6(5):296-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9767350&dopt;=Abstract

Byers T, Vance R, Bigelow C. Controversies in cancer care. High-dose chemotherapy for breast cancer? Cancer Pract 2000 Mar-Apr;8(2):96-8.

Cady B, Evans WP, Feig SA. Breast cancer update: progress and conflict. Patient Care 1997 Jun 15;31:110-24.

Castiglione-Gertsch M, Gelber RD, Goldhirsch A. Adjuvant systemic therapy: the issues of timing and sequence. Recent Results Cancer Res 1996;140:201-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8787063&dopt;=Abstract

Chabner E, Nixon A, Gelman R, Hetelekidis S, Recht A, Bornstein B, Connolly J, Schnitt S, Silver B, Manola J, Harris J, Garber J. Family history and treatment outcome in young women after breast-conserving surgery and radiation therapy for early-stage breast cancer. J Clin Oncol 1998 Jun;16(6):2045-51. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9626202&dopt;=Abstract

Chaos surrounds high-dose chemotherapy for breast cancer [editorial]. Lancet 1999 May 15;353(9165):1633. Comment on: Lancet 1999 Jul 17;354(9174):252-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10335776&dopt;=Abstract

Clark GM, Hilsenbeck SG, Ravdin PM, Osborne CK. Validation of a model that identifies high risk breast cancer patients for clinical trials of intensive therapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A69.

Cohen I, Altaras MM, Shapira J, Tepper R, Rosen DJ, Cordoba M, Zalel Y, Figer A, Yigael D, Beyth Y. Time-dependent effect of tamoxifen therapy on endometrial pathology in asymptomatic postmenopausal breast cancer patients. Int J Gynecol Pathol 1996 Apr;15(2):152-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8786205&dopt;=Abstract

Conte PF, Del Mastro L. Putting the taxanes to work: unanswered questions. Recent Results Cancer Res 1998;152:305-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928567&dopt;=Abstract

Coudert B, Chaplain G, Milan C, Janoray P. Changing, practice in systemic breast cancer adjuvant treatment [abstract]. Paper presented at: 6th International Congress on Anti-Cancer Treatment; 1996 Feb 6-9; Paris.

Crabbe WW. The tamoxifen controversy. Oncol Nurs Forum 1996 Jun;23(5):761-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8792346&dopt;=Abstract

Crown J, Coiffier B, Cortes-Funes H, Guillaume T, Kanz L, Kvalheim G, Marty M, Symann M. ESTIC position paper: high-dose chemotherapy for breast cancer, investigation should continue. Ann Oncol 1999 Aug;10(8):903-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10509150&dopt;=Abstract

Cummings FJ, Saba N. Controversies in breast cancer. Cancer Control 1997;4(3):226-35.

Dabrow MB, Antoniades J. Sequential adjuvant CMF chemotherapy followed by radiotherapy in the treatment of early-stage breast cancer: The Lankenau Hospital Experience. Breast J 1997;3(1):15-8.

Dawson JW, Taylor I. Principles of adjuvant therapy. Br J Hosp Med 1995 Sep 20-Oct 3;54(6):249-54. Comment in: Br J Hosp Med 1995 Sep 20-Oct 3;54(6):248. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8542172&dopt;=Abstract

de Valeriola D, Awada A, Roy JA, Di Leo A, Biganzoli L, Piccart M. Breast cancer therapies in development. A review of their pharmacology and clinical potential. Drugs 1997 Sep;54(3):385-413. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9279502&dopt;=Abstract

Dowsett M. Future uses for aromatase inhibitors in breast cancer. J Steroid Biochem Mol Biol 1997;61(3-6):261-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9365199&dopt;=Abstract

England GM, Jordan VC. Pure antiestrogens as a new therapy for breast cancer. Oncol Res 1997;9(8):397-402. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9436192&dopt;=Abstract

Foster RS Jr, Wood WC. Alternative strategies in the management of primary breast cancer. Arch Surg 1998;133(11):1182-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9820348&dopt;=Abstract

Gee JM, Willsher PC, Kenny FS, Robertson JF, Pinder SE, Ellis IO, Nicholson RI. Endocrine response and resistance in breast cancer: a role for the transcription factor Fos. Int J Cancer 1999 Feb 19;84(1):54-61. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9988233&dopt;=Abstract

Goldhirsch A, Gelber RD, Castiglione M, O'Neill A, Thurlimann B, Rudenstam CM, Lindtner J, Collins J, Forbes J, Crivellari D, Coates A, Cavalli F, Simoncini E, Fey MF, Pagani O, Price K, Senn HJ. Menstrual cycle and timing of breast surgery in premenopausal node- positive breast cancer: Results of the International Breast Cancer Study Group (IBCSG) trial VI. Ann Oncol 1997;8(8):751-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9332682&dopt;=Abstract

Gordon A. The increasing efficacy of breast cancer treatment. Clin Oncol (R Coll Radiol) 1997;9(5):338-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9368731&dopt;=Abstract

Gradishar WJ. Recently initiated studies: neoadjuvant treatments in the next century. Semin Oncol 1999 Feb;26(1 Suppl 3):26-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10203268&dopt;=Abstract

Grann VR, Panageas KS, Whang W, Antman KH, Neugut AI. Decision analysis of prophylactic mastectomy and oophorectomy in brca1-positive or brca2-positive patients. J Clin Oncol 1998;16(3):979-85. Comment in: J Clin Oncol 1998 Jul;16(7):2573-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9508180&dopt;=Abstract

Greco M, Agresti R, Giovanazzi R. Impact of the diagnostic methods on the therapeutic strategies. Q J Nucl Med 1998 Mar;42(1):66-80. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9646647&dopt;=Abstract

Harlap S, Zauber AG, Pollack DM, Tang J, Arena AE, Sternfels P, Borgen P, Norton L. Survival of premenopausal women with breast carcinoma: effects of menstrual timing of surgery. Cancer 1998;83(1):76-88. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9655296&dopt;=Abstract

Harris AL. Anti-angiogenesis therapy and strategies for integrating it with adjuvant therapy. Recent Results Cancer Res 1998;152:341-52. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928571&dopt;=Abstract

Harvey HA. Aromatase inhibitors in clinical practice: current status and a look to the future. Semin Oncol 1996 Aug;23(4 Suppl 9):33-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8824463&dopt;=Abstract

Ibrahim NK, Hortobagyi GN. The evolving role of specific estrogen receptor modulators (SERMs). Surg Oncol 1999;8(2):103-23. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10732962&dopt;=Abstract

Ibrahim NK, Hortobagyi GN. New antiestrogens in breast cancer: a review. Breast J 1998;4(4):213-29.

Imoto S, Ohkura H, Sugano K, Sasaki Y, Ito K, Igarashi T, Ohtsu T, Fujii H, Minami H, Hasebe T, Mukai K. Determination of cytosol c-erbB-2 protein in breast cancer by sandwich enzyme immunoassay. Jpn J Clin Oncol 1998 Feb;28(2):92-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9544822&dopt;=Abstract

Jordan VC. Antiestrogenic action of raloxifene and tamoxifen: today and tomorrow. J Natl Cancer Inst 1998 Jul 1;90(13):967-71. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9665143&dopt;=Abstract

Kennedy MJ. Systemic therapy for breast cancer. Curr Opin Oncol 1997 Nov;9(6):532-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9370074&dopt;=Abstract

Kitchen PR, Cawson JN, Winch KL, Henderson MA. Characteristics and treatment of breast cancers 10 mm or less detected by a mammographic screening programme. Aust N Z J Surg 1998 Jan;68(1):45-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9440456&dopt;=Abstract

Levine M, Ginsburg D, Pritchard K, Crump M, Dhaliwal D, Douglas MS, Down N, Graham I, Holowaty E, Johnston M, Lada B, Laukkanen E, McCready D, Mirsky D, Myers R, O'Malley F, Perera F, Sawka C, Shelley W, Tomiak E, Warr D, Whelan T. The role of adjuvant systemic therapy in node-negative breast cancer. Curr Oncol 1999;6(2):78-89.

Lonning PE. Aromatase inhibitors and their future role in post-menopausal women with early breast cancer. Br J Cancer 1998;78 Suppl 4:12-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9741783&dopt;=Abstract

McGonigle KF, Vasilev SA, Odom-Maryon T, Simpson JF. Ovarian histopathology in breast cancer patients receiving tamoxifen. Gynecol Oncol 1999 Jun;73(3):402-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10366467&dopt;=Abstract

Mouridsen HT. Nordic trials of adjuvant therapy in primary breast cancer. Recent Results Cancer Res 1998;152:441-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928578&dopt;=Abstract

Norton L. Adjuvant breast cancer therapy: current status and future strategies--growth kinetics and the improved drug therapy of breast cancer. Semin Oncol 1999 Feb;26(1 Suppl 3):1-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10203263&dopt;=Abstract

Norton L. Conceptual basis for advances in the systemic drug therapy of breast cancer. Semin Oncol 1997 Aug;24(4 Suppl 11):S11-2-S11-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9314292&dopt;=Abstract

Norton L. Evolving concepts in adjuvant drug therapy of operable breast cancer [abstract]. Paper presented at: 6th International Congress on Anti-Cancer Treatment; 1996 Feb 6-9; Paris.

Overgaard M. Does radiotherapy have a role in high-risk breast cancer patients who also receive systemic adjuvant chemotherapy? [abstract]. Paper presented at: From genes to clinical trials. 25th Jubilee Conference of the New Zealand Society for Oncology; 1996 Feb 13-16; Auckland, New Zealand.

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Singletary SE. New clinical trends in the adjuvant therapy of early stage breast cancer. Acta Oncol 1998;37(5):411-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9831369&dopt;=Abstract

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Sosa JA, Diener-West M, Gusev Y, Choti MA, Lange JR, Dooley WC, Zeiger MA. Association between extent of axillary lymph node dissection and survival in patients with stage I breast cancer. Ann Surg Oncol 1998 Mar;5(2):140-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9527267&dopt;=Abstract

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Thomas TJ, Adhikarakunnathu S, Faaland CA, Thomas T. Identification of a 34 kd cyclin-associated protein as a positive regulator of estrogenic effects on breast cancer cell cycle [abstract]. Proc Annu Meet Am Assoc Cancer Res 1995;36:A197.

Thor AD, Berry DA, Budman DR, Muss HB, Kute T, Henderson IC, Barcos M, Cirrincione C, Edgerton S, Allred C, Norton L, Liu ET. erbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancer. J Natl Cancer Inst 1998 Sep 16;90(18):1346-60. Comment in: J Natl Cancer Inst 1998 Sep 16;90(18):1320-1; J Natl Cancer Inst 1999 Apr 21;91(8):728-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9747866&dopt;=Abstract

Tonetti DA, Jordan VC. The role of estrogen receptor mutations in tamoxifen-stimulated breast cancer. J Steroid Biochem Mol Biol 1997 Jun;62(2-3):119-28. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9393947&dopt;=Abstract

Tsuyuki D, Grass L, Diamandis EP. Frequent detection of mutations in the 5' flanking region of the prostate-specific antigen gene in female breast cancer. Eur J Cancer 1997 Oct;33(11):1851-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9470845&dopt;=Abstract

Valgus JM. Drug update. Emerging therapies for breast cancer... capecitabine... trastuzumab... tamoxifen and raloxifene. Cancer Pract 1999 Mar-Apr;7(2):100-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10352069&dopt;=Abstract

Vujovic O, Perera F, Dar AR, Stitt L, Yu E, Voruganti SM, Truong PT. Does delay in breast irradiation following conservative breast surgery in node-negative breast cancer patients have an impact on risk of recurrence? Int J Radiat Oncol Biol Phys 1998 Mar 1;40(4):869-74. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9531372&dopt;=Abstract

Wallgren A, Bernier J, Gelber RD, Goldhirsch A, Roncadin M, Joseph D, Castiglione-Gertsch M. Timing of radiotherapy and chemotherapy following breast-conserving surgery for patients with node-positive breast cancer. International Breast Cancer Study Group. Int J Radiat Oncol Biol Phys 1996 Jul 1;35(4):649-59. Comment in: Int J Radiat Oncol Biol Phys 1996 Jul 1;35(4):843-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8690630&dopt;=Abstract

Weiss RB, Rifkin RM, Stewart FM, Theriault RL, Williams LA, Herman AA, Beveridge RA. High-dose chemotherapy for high-risk primary breast cancer: an on-site review of the Bezwoda study. Lancet 2000 Mar 18;355(9208):999-1003. Comment in: Lancet 2000 Mar 18;355(9208):942-3; Lancet 2000 Mar 18;355(9208):944-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10768448&dopt;=Abstract

Yu H, Diamandis EP. Prostate-specific antigen (psa) as a new prognostic marker in female breast cancer: molecular characterization and clinical implication [abstract]. Proc Annu Meet Am Assoc Cancer Res 1995;36:A1464.

Zajicek G. A new cancer hypothesis. Med Hypotheses 1996 Aug;47(2):111-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8869926&dopt;=Abstract

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## 2. Factors Used to Select Adjuvant Therapy

### 2a. Tumor-Related Factors

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Abner AL, Collins L, Peiro G, Recht A, Come S, Shulman LN, Silver B, Nixon A, Harris JR, Schnitt SJ, Connolly JL. Correlation of tumor size and axillary lymph node involvement with prognosis in patients with t1 breast carcinoma. Cancer 1998;83(12):2502-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9874455&dopt;=Abstract

Al-Tweigeri T, Magliocco A M, Williams C, Thain C. A modified grading system incorporating ERBB2 status predicts early treatment failure in stage 2 breast cancer treated with adjuvant CMF therapy: A 15 year follow-up study [abstract]. Breast Cancer Res Treat 1997;46(1):66.

Albain KS, Green S, LeBlanc M, Rivkin S, O'Sullivan J, Osborne CK. Proportional hazards and recursive partitioning and amalgamation analyses of the Southwest Oncology Group node-positive adjuvant CMFVP breast cancer data base: a pilot study. Breast Cancer Res Treat 1992;22(3):273-84. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1391993&dopt;=Abstract

Albanell J, Bellmunt J, Molina R, Garcia M, Caragol I, Bermejo B, Ribas A, Carulla J, Gallego OS, Espanol T, Sole Calvo LA. Node-negative breast cancers with p53(-)/HER2-neu(-) status may identify women with very good prognosis. Anticancer Res 1996 Mar-Apr;16(2):1027-32. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8687094&dopt;=Abstract

Alberts SR, Ingle JN, Roche PR, Cha SS, Wold LE, Farr GH Jr, Krook JE, Wieand HS. Comparison of estrogen receptor determinations by a biochemical ligand-binding assay and immunohistochemical staining with monoclonal antibody ER1D5 in females with lymph node positive breast carcinoma entered on two prospective clinical trials. Cancer 1996 Aug 15;78(4):764-72. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8756370&dopt;=Abstract

Allred DC, Clark GM, Elledge R, Fuqua SA, Brown RW, Chamness GC, Osborne CK, McGuire WL. Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst 1993;85(3):200-6. Comment in: J Natl Cancer Inst 1993 Feb 3;85(3):176-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8423624&dopt;=Abstract

Allred DC, Clark GM, Fuqua SA, Elledge RM, Hilsenbeck SG, Ravdin PM, Yee D, Chamness GC, Osborne CK. Biological and clinical implications of the p53 tumor suppressor gene in breast cancer [abstract]. Cancer Invest 1994;12 Suppl 1:39-40.

Allred DC, Clark GM, Fuqua SA, Elledge RM, Hilsenbeck SG, Ravdin PM, Yee D, Chamness GC, Osborne CK. Overexpression of p53 in node-positive breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A111.

Allred DC, Clark GM, Molina R, Tandon AK, Scnitt SJ, Gilchrist KW, Osborne CK, Tormey DC, Mcguire WL. Overexpression of HER-2/neu and its relationship with other prognostic factor change during progression of in situ to invasive breast cancer. Hum Pathol 1992 Sep;23(9):974-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1355464&dopt;=Abstract

Allred DC, Clark GM, Tandon AK, Molina R, Tormey DC, Osborne CK, Gilchrist KW, Mansour EG, Abeloff M, Eudey L, et al. HER-2/neu in node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in situ carcinoma. J Clin Oncol 1992 Apr;10(4):599-605. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1548522&dopt;=Abstract

Allred DC, Harvey JM, Berardo M, Clark GM. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol 1998 Feb;11(2):155-68. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9504686&dopt;=Abstract

Amadori D, Marangolo M, Pacini P, Ravaioli A, Rossi A, Gambi A, Catalano G, Perrone D, Giunchi D Casadei, Becciolini A, Volpi A, Nanni O. N-breast cancer patients: Prospective use of tumour proliferative activity for adjuvant therapy. Int J Biol Markers 1996;11(2):132-3.

Amornmarn R, Bui MM, Prempree TB, Masood S. Molecular predictive factors for local recurrence and distant metastasis of breast cancer after lumpectomy with postoperative radiation therapy. Ann Clin Lab Sci 2000 Jan;30(1):33-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10678581&dopt;=Abstract

Anbazhagan R, Gelber RD, Bettelheim R, Goldhirsch A, Gusterson BA. Association of c-erbB-2 expression and S-phase fraction in the prognosis of node positive breast cancer. Ann Oncol 1991 Jan;2(1):47-53. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1672597&dopt;=Abstract

Andrulis IL, Bull SB, Blackstein ME, Sutherland D, Mak C, Sidlofsky S, Pritzker KP, Hartwick RW, Hanna W, Lickley L, Wilkinson R, Qizilbash A, Ambus U, Lipa M, Weizel H, Katz A, Baida M, Mariz S, Stoik G, Dacamara P, Strongitharm D, Geddie W, McCready D. neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. Toronto Breast Cancer Study Group. J Clin Oncol 1998 Apr;16(4):1340-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9552035&dopt;=Abstract

Archer CD, Ashley S, Dowsett M, Smith IE. Biomarkers for the prediction of complete clinical response to primary chemotherapy in early breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A484.

Armas OA, Gerald WL, Lesser ML, Arroyo CD, Norton L, Rosen PP. Immunohistochemical detection of cathepsin d in t2n0m0 breast carcinoma. Am J Surg Pathol 1994;18(2):158-66. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8291654&dopt;=Abstract

Arroyo CD, Cranor M, Borgen P, Norton L. P53 in node-negative breast carcinoma: an immunohistochemical study of epidemiologic risk factors, histologic features, and prognosis. J Clin Oncol 1995 Apr;13(4):821-30. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7707107&dopt;=Abstract

Balslev I, Axelsson CK, Zedeler K, Rasmussen BB, Carstensen B, Mouridsen HT. The Nottingham Prognostic Index applied to 9,149 patients from the studies of the Danish Breast Cancer Cooperative Group (DBCG). Breast Cancer Res Treat 1994;32(3):281-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7865856&dopt;=Abstract

Balslev I, Christensen IJ, Rasmussen BB, Larsen JK, Lykkesfeldt AE, Thorpe SM, Rose C, Briand P, Mouridsen HT. Flow cytometric DNA ploidy defines patients with poor prognosis in node-negative breast cancer. Int J Cancer 1994 Jan 2;56(1):16-25. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8262673&dopt;=Abstract

Barbareschi M, Caffo O, Veronese S, Leek RD, Fina P, Fox S, Bonzanini M, Girlando S, Morelli L, Eccher C, Pezzella F, Doglioni C, Dalla Palma P, Harris A. Bcl-2 and p53 expression in node-negative breast carcinoma: a study with long-term follow-up. Hum Pathol 1996 Nov;27(11):1149-55. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8912823&dopt;=Abstract

Barbareschi M, Doglioni C, Veronese S, Bonzanini M, Dalla Palma P, Harris AL, Caffo O. p21WAF1 and p53 immunohistochemical expression in breast carcinoma may predict therapeutic response to adjuvant treatment [letter]. Eur J Cancer 1996 Nov;32A(12):2182-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9014765&dopt;=Abstract

Barnes DM, Smith S, Rubens RD. The relationship between outcome following adjuvant CMF and the presence of estrogen receptor and c-ERBB|2 protein in 277 women with primary breast cancer [abstract]. Breast Cancer Res Treat 1997;46(1):65.

Bartsch H, Phillips DH, Nair J, Hewer A, Meyberg-Solomeyer G, Grischke EM. Lack of evidence for tamoxifen- and toremifene-DNA adducts in lymphocytes of treated patients. Carcinogenesis 2000 Apr;21(4):845-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10753226&dopt;=Abstract

Baselga J, Seidman AD, Rosen PP, Norton L. HER2 overexpression and paclitaxel sensitivity in breast cancer: therapeutic implications. Oncology (Huntingt) 1997 Mar;11(3 Suppl 2):43-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9110342&dopt;=Abstract

Benini E, Daidone MG, Silvestrini R. p53 gene mutation and cell proliferation in breast cancer. Cell Prolif 1997;30(10-12):470.

Benini E, Rao S, Daidone MG, Pilotti S, Silvestrini R. Immunoreactivity to mib-1 in breast cancer: methodological assessment and comparison with other proliferation indices. Cell Prolif 1997;30(3-4):107-15. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9375023&dopt;=Abstract

Benini E, Silvestrini R, Daidone MG, Canova S. Detection of p53 expression and s-phase cell fraction in paraffin-embedded tissue by a double-labeling technique. J Histochem Cytochem 1995;43(10):999-1003. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7560890&dopt;=Abstract

Berardo M, Clark GM, de Moor C, Osborne CK, Weigand RA, Allred DC. Prognostic and predictive properties of immunohistochemical progesterone receptors in breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A139.

Berardo M, de Moor C, Clark GM, Osborne CK, Allred DC. Bcl-2 expression in node-positive breast cancer [abstract]. Breast Cancer Res Treat 1996;37 Suppl:37.

Berardo MD, Elledge RM, de Moor C, Clark GM, Osborne CK, Allred DC. Bcl-2 and apoptosis in lymph node positive breast carcinoma. Cancer 1998;82(7):1296-302. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9529021&dopt;=Abstract

Bergh J, Norberg T, Sjogren S, Lindgren A, Holmberg L. Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy. Nat Med 1995 Oct;1(10):1029-34. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7489358&dopt;=Abstract

Bergh J, Norberg T, Sjogren S, Lindgren A, Holmberg L. Sequenced based diagnosis of the complete p53 gene provides information on the response to adjuvant therapy in lymph node positive and lymph node negative breast cancer patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A128.

Berns EM, Klijn JG, van Putten WL, de Witte HH, Look MP, Meijer-van Gelder ME, Willman K, Portengen H, Benraad TJ, Foekens JA. p53 protein accumulation predicts poor response to tamoxifen therapy of patients with recurrent breast cancer. J Clin Oncol 1998 Jan;16(1):121-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9440732&dopt;=Abstract

Berns PM, de Witte HH, Klijn JG, Willman K, Look MP, Meijer-van Gelder M, Portengen H, Benraad T, Foekens JA. Prognostic value of p53 protein overexpression in human primary and recurrent breast cancer: an analysis by luminometric immunoassay (lia) on 1491 tumor cytosols [abstract]. Anticancer Res 1995;15(6A):2416.

Bettelheim R, Price KN, Gelber RD, Davis BW, Castiglione M, Goldhirsch A, Neville AM. Prognostic importance of occult axillary lymph node micrometastases from breast cancers. Lancet 1990;335(8705):1565-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1972494&dopt;=Abstract

Bevilacqua P, Barbareschi M, Verderio P, Boracchi P, Caffo O, Dalla Palma P, Meli S, Weidner N, Gasparini G. Prognostic value of intratumoral microvessel density, a measure of tumor angiogenesis, in node-negative breast carcinoma: results of a multiparametric study. Breast Cancer Res Treat 1995;36(2):205-17. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8534868&dopt;=Abstract

Bianchi S, Calzolari A, Vezzosi V, Zampi G, Cardona G, Cataliotti L, Bonardi R, Ciatto S. Lack of prognostic value of p53 protein expression in node-negative breast cancer. Tumori 1997 May-Jun;83(3):669-72. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9267486&dopt;=Abstract

Billgren AM, Rutqvist LE, Johansson H, Skoog L. The role of cathepsin D and PAI-1 in primary invasive breast cancer as prognosticators and predictors of treatment benefit with adjuvant tamoxifen [abstract]. Breast Cancer Res Treat 1999;57(1):99.

Bitran JD, Samuels B, Trujillo Y, Klein L, Schroeder L, Martinec J. Her2/neu overexpression is associated with treatment failure in women with high-risk stage II and stage IIIA breast cancer (>10 involved lymph nodes) treated with high-dose chemotherapy and autologous hematopoietic progenitor cell support following standard-dose adjuvant chemotherapy. Clin Cancer Res 1996 Sep;2(9):1509-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9816327&dopt;=Abstract

Blanco AR, Laurentils M D, Carlomagno C, Lauria R, Petrella G, Panico L, Pettinato G, Perrone F, Gallo C, Marinelli A, Placido SD. 20 year update of the naples gun trial of adjuvant breast cancer therapy: evidence of interaction between c-erb-b2 expression and tamoxifen efficacy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A373.

Blaszyk H, Hartmann A, Cunningham JM, Schaid D, Wold LE, Kovach JS, Sommer SS. A prospective trial of midwest breast cancer patients: A p53 gene mutation is the most important predictor of adverse outcome. Int J Cancer 2000;89(1):32-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10719728&dopt;=Abstract

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Ferno M, Bendahl PO, Borg A, Brundell J, Hirschberg L, Olsson H, Killander D. Urokinase plasminogen activator, a strong independent prognostic factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay. Eur J Cancer 1996 May;32A(5):793-801. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9081356&dopt;=Abstract

Ferrero JM, Etienne MC, Formento JL, Francoual M, Rostagno P, Peyrottes I, Ettore F, Teissier E, Leblanc-Talent P, Namer M, Milano G. Application of an original RT-PCR-ELISA multiplex assay for MDR1 and MRP, along with p53 determination in node-positive breast cancer patients. Br J Cancer 2000;82(1):171-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10638986&dopt;=Abstract

Fioravanti L, Cappelletti V, Coradini D, Miodini P, Borsani G, Daidone MG, Di Fronzo G. int-2 oncogene amplification and prognosis in node-negative breast carcinoma. Int J Cancer 1997 Dec 19;74(6):620-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9421359&dopt;=Abstract

Fisher B, Costantino J, Bryant J, Gunduz N, Fisher E, Mamounas E, DeCillis A, Wickerham DL, Paik S, Dimitrov N, Bowman D, Margolese R, Kavanah M, Shibata H. Effect of selected prognostic markers on node-negative breast cancer patients with er-positive tumors: 10-year results from nsabp b-14 [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A455.

Fisher B, Dignam J, Bryant J, DeCillis A, Wickerham DL, Wolmark N, Costantino J, Redmond C, Fisher ER, Bowman DM, Deschenes L, Dimitrov NV, Margolese RG, Robidoux A, Shibata H, Terz J, Paterson AHG, Feldman MI, Farrar W, et al. Five versus more than five years of tamoxifen therapy for breast cancer patients with negative lymph nodes and estrogen receptor-positive tumors. J Natl Cancer Inst 1996;88(21):1529-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8901851&dopt;=Abstract

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Foekens JA, Look MP, Bolt-De Vries J, Emeijer-Van Gelder M, Van Putten WL, Klijn JG. Cathepsin-D in primary breast cancer: Prognostic evaluation involving 2810 patients. Br J Cancer 1999;79(2):300-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9888472&dopt;=Abstract

Foekens JA, Peters HA, Look MP, Portengen H, Schmitt M, Kramer MD, Brunner N, Janicke F, Meijer-van Gelder ME, Henzen-Logmans SC, van Putten WL, Klijn JG. The urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients. Cancer Res 2000;60(3):636-43. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10676647&dopt;=Abstract

Fountzilas G, Vasilaros S, Koukouras D, Malamos N, Pectasides D, Adamou A, Nenopoulou E, Kiriakou K, Zouvani I, Katsohis K, Kappas A, Skopa C, Semoglou C, Fahantidis E, Konstantaras C, Vasilaki E, Economopoulos T, Bacoyiannis H, Bafaloukos D, Razi E, Polichronis A, Androulakis G, Papaioannou T, Pavlidis N, Kosmidis P, et al. Prognostic variables in greek patients with stage II breast cancer: a Hellenic Cooperative Oncology Group study. Anticancer Res 1997 Nov-Dec;17(6D):4681-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9494589&dopt;=Abstract

Fowble B, Hanlon AL, Patchefsky A, Freedman G, Hoffman JP, Sigurdson ER, Goldstein LJ. The presence of proliferative breast disease with atypia does not significantly influence outcome in early-stage invasive breast cancer treated with conservative surgery and radiation. Int J Radiat Oncol Biol Phys 1998 Aug 1;42(1):105-15. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9747827&dopt;=Abstract

Fox SB, Engels K, Comley M, Whitehouse RM, Turley H, Gatter KC, Harris AL. Relationship of elevated tumour thymidine phosphorylase in node-positive breast carcinomas to the effects of adjuvant CMF. Ann Oncol 1997 Mar;8(3):271-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9137797&dopt;=Abstract

Fox SB, Gasparini G, Bevilacqua P, Harris AL. Angiogenesis predicts clinical outcome of node-positive breast cancer patients treated with adjuvant tamoxifen [abstract]. Proc Am Assoc Cancer Res Annu Meet 1996;37:195.

Frassoldati A, Adami F, Banzi C, Criscuolo M, Piccinini L, Silingardi V. Changes of biological features in breast cancer cells determined by primary chemotherapy. Breast Cancer Res Treat 1997 Jul;44(3):185-92. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9266097&dopt;=Abstract

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Freedman GM, Fowble BL, Hanlon AL, Myint MA, Hoffman JP, Sigurdson ER, Eisenberg BL, Goldstein LJ, Fein DA. A close or positive margin after mastectomy is not an indication for chest wall irradiation except in women aged fifty or younger. Int J Radiat Oncol Biol Phys 1998 Jun 1;41(3):599-605. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9635708&dopt;=Abstract

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Fritz M, Schmidt B, Heidemann E, Brinkmann F, Benoehr C, Bittner R, Von Gaisberg U, Herschlein HJ, Jipp P, Karg C, Kieninger G, Littmann K, Meisner C, Merkle P, Metzger H, Strosche H, Widmaier G. Does adjuvant systemic therapy improve prognosis in breast cancer with 4-9 axillary nodes and in the age group of 80 years or more? Onkologie 1998;21(5):394-400.

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Gasparini G, Fox SB, Verderio P, Bonoldi E, Bevilacqua P, Boracchi P, Dante S, Marubini E, Harris AL. Determination of angiogenesis adds information to estrogen receptor status in predicting the efficacy of adjuvant tamoxifen in node-positive breast cancer patients. Clin Cancer Res 1996 Jul;2(7):1191-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9816287&dopt;=Abstract

Gasparini G, Toi M, Miceli R, Vermeulen PB, Dittadi R, Biganzoli E, Morabito A, Fanelli M, Gatti C, Suzuki H, Tominaga T, Dirix LY, Gion M. Clinical relevance of vascular endothelial growth factor and thymidine phosphorylase in patients with node-positive breast cancer treated with either adjuvant chemotherapy or hormone therapy. Cancer J Sci Am 1999 Mar-Apr;5(2):101-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10198732&dopt;=Abstract

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Gazet JC, Coombes RC, Ford HT, Griffin M, Corbishley C, Makinde V, Lowndes S, Quilliam J, Sutcliffe R. Assesssment of the effect of pretreatment with neoadjuvant therapy on primary breast cancer. Br J Cancer 1996 Mar;73(6):758-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8611376&dopt;=Abstract

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Gilchrist KW, Gray R, Fowble B, Tormey DC, Taylor SG 4th. Tumor necrosis is a prognostic predictor for early recurrence and death in lymph node-positive breast cancer: a 10-year follow-up study of 728 Eastern Cooperative Oncology Group patients. J Clin Oncol 1993;11(10):1929-35. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8410120&dopt;=Abstract

Gilchrist KW, Gray R, van Driel-Kulker AM, Mesker WE, Ploem-Zaaijer JJ, Ploem JS, Taylor SG, Tormey DC. High dna content and prognosis in lymph node positive breast cancer. A case control study by the university of leiden and ECOG. (Eastern Cooperative Oncology Group). Breast Cancer Res Treat 1993;28(1):1-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8123866&dopt;=Abstract

Gillett CE, Smith P, Gregory WM, Richards MA, Millis RR, Peters G, Barnes DM. Cyclin d1 as a marker of response to endocrine therapy in breast carcinoma [abstract]. J Pathol 1996;178 Suppl:26A.

Gion M, Boracchi P, Dittadi R, Biganzoli E, Peloso L, Gatti C, Paccagnella A, Rosabian A, Vinante O, Meo S. Quantitative measurement of soluble cytokeratin fragments in tissue cytosol of 599 node negative breast cancer patients: A prognostic marker possibly associated with apoptosis. Breast Cancer Res Treat 2000;59(3):211-21. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10832591&dopt;=Abstract

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Gradishar WJ. Inflammatory breast cancer: The evolution of multimodality treatment strategies. Semin Surg Oncol 1996;12(5):352-63. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8873324&dopt;=Abstract

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Hall PD, Lesher BA, Hall RK. Adjuvant therapy of node-negative breast cancer. Ann Pharmacother 1995 Mar;29(3):289-98. Comment in: Ann Pharmacother 1995 Sep;29(9):940-1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7606076&dopt;=Abstract

Han S, Park K, Kim HY, Lee MS, Kim HJ, Kim YD. Reduced expression of p27Kip1 protein is associated with poor clinical outcome of breast cancer patients treated with systemic chemotherapy and is linked to cell proliferation and differentiation. Breast Cancer Res Treat 1999 May;55(2):161-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10481943&dopt;=Abstract

Han S, Park K, Kim HY, Lee MS, Kim HJ, Kim YD, Yuh YJ, Kim SR, Suh HS. Clinical implication of altered expression of Mad1 protein in human breast carcinoma. Cancer 2000 Apr 1;88(7):1623-32. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10738221&dopt;=Abstract

Han S, Yun IJ, Noh DY, Choe KJ, Song SY, Chi JG. Abnormal expression of four novel molecular markers represents a highly aggressive phenotype in breast cancer. Immunohistochemical assay of p53, nm23, erbB-2, and cathepsin D protein. J Surg Oncol 1997 May;65(1):22-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9179263&dopt;=Abstract

Hansen S, Grabau DA, Soerensen FB, Bak M, Vach W, Rose C. The prognostic impact of angiogenesis in 836 primary breast cancer patients in a prognostic phase III study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A2355.

Harbeck N, Dettmar P, Thomssen C, Berger U, Ulm K, Kates R, Hofler H, Janicke F, Graeff H, Schmitt M. Risk-group discrimination in node-negative breast cancer using invasion and proliferation markers: 6-year median follow-up. Br J Cancer 1999 May;80(3-4):419-26. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10408848&dopt;=Abstract

Harbeck N, Ross JS, Yurdseven S, Dettmar P, Polcher M, Kuhn W, Ulm K, Graeff H, Schmitt M. HER-2/neu gene amplification by fluorescence in situ hybridization allows risk-group assessment in node-negative breast cancer. Int J Oncol 1999 Apr;14(4):663-71. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10087312&dopt;=Abstract

Harding C, Osundeko O, Tetlow L, Faragher EB, Howell A, Bundred NJ. Hormonally-regulated proteins in breast secretions are markers of target organ sensitivity. Br J Cancer 2000 Jan;82(2):354-60. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10646888&dopt;=Abstract

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Harvey JM, Clark GM, Osborne CK, Allred DC. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 1999 May;17(5):1474-81. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10334533&dopt;=Abstract

Hata Y, Takahashi H, Sasaki F, Ogita M, Une Y, Uchino J, Yoshimoto M, Akasaka Y, Nakanishi Y, Sawada Y. Intratumoral pyrimidine nucleoside phosphorylase (pynpase) activity predicts a selective effect of adjuvant5'-deoxy-5-fluorouridine (5'-dfur) on breast cancer: a prognostic factor of breast cancer (pfbc) trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A552.

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Hieken TJ, Mehta RR, Shilkaitis A, Wild LD, Das Gupta TK. Her-2/neu and p53 expression in breast cancer: valid prognostic markers when assessed by direct immunoassay, but not by immunohistochemistry [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A113.

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Hohaus S, Funk L, Martin S, Schlenk RF, Abdallah A, Hahn U, Egerer G, Goldschmidt H, Schneeweiss A, Fersis N, Kaul S, Wallwiener D, Bastert G, Haas R. Stage III and oestrogen receptor negativity are associated with poor prognosis after adjuvant high-dose therapy in high-risk breast cancer. Br J Cancer 1999 Mar;79(9-10):1500-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10188897&dopt;=Abstract

Hohenberger P, Felgner C, Haensch W, Schlag PM. Tumor oxygenation correlates with molecular growth determinants in breast cancer. Breast Cancer Res Treat 1998;48(2):97-106. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9596481&dopt;=Abstract

Huang A, Leygue E, Dotzlaw H, Murphy LC, Watson PH. Influence of estrogen receptor variants on the determination of ER status in human breast cancer. Breast Cancer Res Treat 1999 Dec;58(3):219-25. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10718484&dopt;=Abstract

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Ito KI, Fujimori M, Nakata S, Hama Y, Shingu K, Kobayashi S, Tsuchiya SI, Kohno K, Kuwano M, Amano J. Clinical significance of the increased multidrug resistance-associated protein (MRP) gene expression in patients with primary breast cancer. Oncol Res 1998;10(2):99-109. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9666517&dopt;=Abstract

Iwaya K, Tsuda H, Fukutomi T, Tsugane S, Suzuki M, Hirohashi S. Histologic grade and p53 immunoreaction as indicators of early recurrence of node-negative breast cancer. Jpn J Clin Oncol 1997 Feb;27(1):6-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9070333&dopt;=Abstract

Jacquemier JD, Penault-Llorca FM, Bertucci F, Sun ZZ, Houvenaeghel GF, Geneix JA, Puig BD, Bardou VJ, Hassoun JA, Birnbaum D, Viens PJ. Angiogenesis as a prognostic marker in breast carcinoma with conventional adjuvant chemotherapy: a multiparametric and immunohistochemical analysis. J Pathol 1998 Feb;184(2):130-5. Comment in: J Pathol 1998 Feb;184(2):119-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9602702&dopt;=Abstract

Jager JJ, Jansen RL, Arends JW, Joosten-Achjanie S, Volovics L, Schouten LJ, De Jong JM, Meyenfeldt MF, Blijham GH. Anti-apoptotic phenotype is associated with decreased locoregional recurrence rate in breast cancer. Anticancer Res 2000 Mar-Apr;20(2B):1269-75. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10810433&dopt;=Abstract

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Jahkola T, Toivonen T, Virtanen I, Von Smitten K, Nordling S, Von Boguslawski K, Haglund C, Nevanlinna H, Blomqvist C. Tenascin-C expression in invasion border of early breast cancer: a predictor of local and distant recurrence. Br J Cancer 1998;78(11):1507-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9836485&dopt;=Abstract

Jalava PJ, Collan YU, Kuopio T, Juntti-Patinen L, Kronqvist P. Bcl-2 immunostaining: a way to finding unresponsive postmenopausal N+ breast cancer patients. Anticancer Res 2000 Mar-Apr;20(2B):1213-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10810424&dopt;=Abstract

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Johnston SR, Saccani-Jotti G, Newby J, Dowsett M, Smith IE. Change in oestrogen receptor expression and function in tamoxifen-resistant breast cancer. Endocr Relat Cancer 1995;2(1):105-10.

Johnston SR, Saccani-Jotti G, Smith IE, Salter J, Newby J, Coppen M, Ebbs SR, Dowsett M. Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifen-resistant human breast cancer. Cancer Res 1995 Aug 1;55(15):3331-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7614468&dopt;=Abstract

Jones S, Clark G, Koleszar S, Ethington G, Mennel R, Paulson S, Brooks B, Kerr R, Denham C, Savin M, White C, Blum J, Kirby R, Stone M, Pippen J, Kitchens L, George T, Cooper B, Peters G, Knox S, Grant M, Cheek H, Jones R, Kuhn J, Lieberman Z. Low proliferative rate of invasive node negative breast cancer predicts for a favorable outcome without adjuvant chemotherapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A262.

Jordan VC. Third annual William L. McGuire Memorial Lecture. "Studies on the estrogen receptor in breast cancer"--20 years as a target for the treatment and prevention of cancer. Breast Cancer Res Treat 1995;36(3):267-85. Available from: http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8573710&dopt;=Abstract

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Kandioler-Eckersberger D, Ludwig C, Rudas M, Kappel S, Janschek E, Wenzel C, Schlagbauer-Wadl H, Mittlbock M, Gnant M, Steger G, Jakesz R. TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients. Clin Cancer Res 2000 Jan;6(1):50-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10656431&dopt;=Abstract

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Kenny FS, Hui R, Musgrove EA, Gee JM, Blamey RW, Nicholson RI, Sutherland RL, Robertson JF. Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptor-positive breast cancer. Clin Cancer Res 1999 Aug;5(8):2069-76. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10473088&dopt;=Abstract

Knowlden JM, Gee JM, Seery LT, Farrow L, Gullick WJ, Ellis IO, Blamey RW, Robertson JF, Nicholson RI. c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer. Oncogene 1998 Oct 15;17(15):1949-57. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9788438&dopt;=Abstract

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Lah TT, Cercek M, Blejec A, Kos J, Gorodetsky E, Somers R, Daskal I. Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: comparison with cathepsin D, cathepsin L, and other clinical indicators. Clin Cancer Res 2000 Feb;6(2):578-84. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10690542&dopt;=Abstract

Lampe B, Hantschmann P, Dimpfl T. Prognostic relevance of immunohistology, tumor size and vascular space involvement in axillary node negative breast cancer. Arch Gynecol Obstet 1998;261(3):139-46. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9651658&dopt;=Abstract

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Lelli G, Di Micco CM, Morritti MG, Nanni L, Tardio B, Murgo R, Bisceglia M, Flamini G, Cittadini A, Boninsegna A, et al. Does glycoprotein p-170 (gp-170) have a prognostic relevance in operated breast cancer? [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A1626.

Levin E, Actis AM, Caruso S, Gass H, Romero R, Qualeta N, Levin RW. Evaluation of a displacement assay with tamoxifen as prognostic indicator in breast-cancer patients with estrogen-receptor-positive tumors. Int J Cancer 1997 Nov 14;73(4):486-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9389560&dopt;=Abstract

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### 2b. Patient-Related Factors

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Garcia-Carbonero R, Hidalgo M, Paz-Ares L, Calzas J, Gomez H, Guerra JA, Hitt R, Hornedo J, Colomer R, Cortes-Funes H. Patient selection in high-dose chemotherapy trials: relevance in high-risk breast cancer. J Clin Oncol 1997 Oct;15(10):3178-84. Comment in: J Clin Oncol 1997 Oct;15(10):3169-70; J Clin Oncol 1998 Feb;16(2):810-1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9336353&dopt;=Abstract

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Goss PE, Reid C, Pintilie M, Lim R, Miller N. Male breast carcinoma: a review of 229 patients who presented to the Princess Margaret Hospital during 40 years: 1955-1996. Cancer 1999 Feb 1;85(3):629-39. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10091736&dopt;=Abstract

Gratus C. Patients' expectations of adjuvant cytotoxic chemotherapy [letter]. Lancet 1998 Aug 15;352(9127):581-2. Comment on: Lancet 1998 May 16;351(9114):1506-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9716097&dopt;=Abstract

Green S, Furr B. Prospects for the treatment of endocrine-responsive tumours. Endocr Relat Cancer 1999 Sep;6(3):349-71. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10516851&dopt;=Abstract

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Knobf MT, Pasacreta J. Use of alternative medicine by women with breast cancer [letter]. N Engl J Med 1999 Oct 7;341(15):1156-7. Comment on: N Engl J Med 1999 Jun 3;340(22):1733-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10515762&dopt;=Abstract

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Pagani O, O'Neill A, Castiglione M, Gelber RD, Goldhirsch A, Rudenstam CM, Lindtner J, Collins J, Crivellari D, Coates A, Cavalli F, Thurlimann B, Simoncini E, Fey M, Price K, Senn HJ. Prognostic impact of amenorrhoea after adjuvant chemotherapy in premenopausal breast cancer patients with axillary node involvement: results of the International Breast Cancer Study Group (IBCSG) Trial VI. Eur J Cancer 1998 Apr;34(5):632-40. Comment in: Eur J Cancer 1998 Apr;34(5):603-5; Eur J Cancer 1998 Apr;34(5):606-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9713266&dopt;=Abstract

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Silber JH, Fridman M, DiPaola RS, Erder MH, Pauly MV, Fox KR. First-cycle blood counts and subsequent neutropenia, dose reduction, or delay in early-stage breast cancer therapy. J Clin Oncol 1998 Jul;16(7):2392-400. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9667256&dopt;=Abstract

Silliman RA, Demissie S, Troyan SL. The care of older women with early-stage breast cancer: what is the role of surgeon gender? Med Care 1999 Oct;37(10):1057-67. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10524372&dopt;=Abstract

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Simon MS, Chuba PJ. Age and racial differences in primary surgical and radiation therapy for localized breast cancer in the detroit metropolitan area 1973-1992 [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A670.

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Stevenson J, Giantonio B, Boyd RL, Bruner JA. Adjuvant chemotherapy for breast cancer in pregnancy: can recommendations be made with confidence. Semin Oncol 1997 Apr;24(2):xxv-xxxvi; discussion xxxvi, xxxix. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9129684&dopt;=Abstract

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Valentini M, Mari E, Belfiglio M, Nicolucci A. Is adjuvant tamoxifen used optimally in the treatment of breast cancer? Results of an Italian survey. Ann Oncol 1999 Jul;10(7):789-93. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10470425&dopt;=Abstract

Valero V, Buzdar AU, Asmar L, Theriault RL, Booser D, McNeese M, Singletary SE, Hortobagyi GN. Benefits of adjuvant doxorubicin/cyclophosphamide-containing therapy in women with breast cancer by age (<60, 60-69, >69): the University of Texas MD Anderson Cancer Center experience [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A2233.

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## 3. Adjuvant Hormonal Therapy

### 3a. Tamoxifen

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Andersson M, Kamby C, Jensen M-B, Mouridsen H, Ejlertsen B, Dombernowsky P, Rose C, Cold S, Overgaard M, Andersen J, Kjaer M. Tamoxifen in high-risk premenopausal women with primary breast cancer receiving adjuvant chemotherapy. Report from the Danish Breast Cancer Co-operative Group DBCG 82B trial. Eur J Cancer 1999 Nov;35(12):1659-66. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10674010&dopt;=Abstract

Arriagada R. Tamoxifen in early breast cancer [letter]. Lancet 1998 Aug 1;352(9125):403-4. Comment on: Lancet 1998 May 16;351(9114):1451-67. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9717953&dopt;=Abstract

Barnish L. Tamoxifen: scientific basis, use and nursing implications. Br J Nurs 1995 Jan 12-25;4(1):22, 39-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7881246&dopt;=Abstract

Baum M. Tamoxifen--the treatment of choice. Why look for alternatives? Br J Cancer 1998 Sep;78 Suppl 4:1-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9741780&dopt;=Abstract

Benson JR. Tamoxifen in early breast cancer [letter]. Lancet 1998 Aug 1;352(9125):404-5. Comment on: Lancet 1998 May 16;351(9114):1451-67. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9717955&dopt;=Abstract

Bertheault-Cvitkovic F, Garbay JR, Cohen C Cohen Sola Le Nir, Stevens D, Tubiana-Hulin M, Berlie J, Rouesse J. Adjuvant tamoxifen in 1012 elderly (greater than or equal to 70 years) women after mastectomy and axillary node dissection: The 1978-1992 experience of Centre Rene huguenin [abstract]. Breast Cancer Res Treat 1997;46(1):32.

Bilimoria MM, Jordan VC. The duration of adjuvant tamoxifen therapy. Cancer Treat Res 1998;94:181-93. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9587688&dopt;=Abstract

Bissett D, Harnett AN, Canney PA, McMurray A, Leake R, George WD, Paul J, Kaye SB. Sequential tamoxifen and megestrol acetate with continuous norethisterone in postmenopausal breast cancer: A feasibility study. Breast 1996;5(2):92-5.

Bogden AE, Keyes SR, Grant W, Zwicker S, Silver M, Batista IL, LePage D. Therapeutic benefit of a lanreotide-tamoxifen combination in the treatment of breast tumors [abstract]. Proc Annu Meet Am Assoc Cancer Res 1995;36:A1507.

Bolla M, Mousseau M, Winckel P, Marron-Charriere J, Colonna M, Pasquier D, Chedin M, Panh MH, Seigneurin D, Salvat J, Payan R, Froget, Schaerer R, Vrousos C. Modulation of the indications of adjuvant hormonal treatment by tamoxifen in t1t2/n0n1 breast carcinomas. Preliminary results of a multicenter study including 695 cases [abstract]. Paper presented at: 6th International Congress on Anti-Cancer Treatment; 1996 Feb 6-9; Paris.

Brotherick I, Browell DA, Shenton BK, Egan M, Cunliffe WJ, Webb LA, Lunt LG, Young JR, Higgs MJ. The effect of 3-week tamoxifen treatment on oestrogen receptor levels in primary breast tumours: a flow cytometric study. Br J Cancer 1998 May;77(10):1657-60. Comment in: Br J Cancer 1999 Mar;79(9-10):1621. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9635844&dopt;=Abstract

Bryce CJ. Tamoxifen in early breast cancer [letter]. Lancet 1998 Aug 1;352(9125):403. Comment on: Lancet 1998 May 16;351(9114):1451-67. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9717952&dopt;=Abstract

Bulbrook RD. Adjuvant treatment with tamoxifen. Care is necessary [letter]. BMJ 1996 Aug 24;313(7055):493-4. Comment on: BMJ 1996 Apr 20;312(7037):1036; BMJ 1996 Apr 20;312(7037):1036-7. Comment in: BMJ 1996 Dec 7;313(7070):1484. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8776337&dopt;=Abstract

Buzdar A, Frye D, Ho D, Booser D, Valero V, Holmes F, Plourde P, Hortobagyi GN. Bioavailability of 20 mg tamoxifen citrate (nolvadex-d) once a day to 10 mg administered twice daily in patients (pts) with breast cancer: results of a prospective randomized trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1993;12:A317.

Buzdar AU, Hortobagyi GN, Frye D, Ho D, Booser DJ, Valero V, Holmes FA, Birmingham BK, Bui K, Yeh C, et al. Bioequivalence of 20-mg once-daily tamoxifen relative to 10-mg twice-daily tamoxifen regimens for breast cancer. J Clin Oncol 1994;12(1):50-4. Published erratum appears in J Clin Oncol 1994 Jun;12(6):1337. Comment in: J Clin Oncol 1994 Sep;12(9):1993-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8270984&dopt;=Abstract

Cameron DA. More large trials needed to decide best duration of treatment with tamoxifen [letter]. BMJ 1998 Nov 28;317(7171):1524. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9831594&dopt;=Abstract

Carlson RW. Scientific review of tamoxifen. Overview from a medical oncologist. Semin Oncol 1997 Feb;24(1 Suppl 1):S1-151-S1-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9045312&dopt;=Abstract

Cooke AL, Perera F, Fisher B, Opeitum A, Yu N. Tamoxifen with and without radiation after partial mastectomy in patients with involved nodes. Int J Radiat Oncol Biol Phys 1995;31(4):777-81. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7860388&dopt;=Abstract

Corder AP. Adjuvant treatment with tamoxifen. Multicentre trial should be welcomed [letter]. BMJ 1996 Apr 20;312(7037):1037. Comment on: BMJ 1996 Feb 17;312(7028):389-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8616360&dopt;=Abstract

Cummings FJ, Gray R, Tormey DC, Davis TE, Volk H, Harris J, Falkson G, Bennett JM. Adjuvant tamoxifen versus placebo in elderly women with node-positive breast cancer: Long-term follow-up and causes of death. J Clin Oncol 1993;11(1):29-35. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8418238&dopt;=Abstract

Cunningham H. Adjuvant treatment with tamoxifen. Informed consent and follow up in aTTom trial are inadequate [letter]. BMJ 1996 Aug 24;313(7055):494. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8776338&dopt;=Abstract

Davies C, McGale P, Peto R. Variation in use of adjuvant tamoxifen [letter]. Lancet 1998 May 16;351(9114):1487-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9605808&dopt;=Abstract

Delozier T, Spielmann M, Mace-Lesech J, Janvier M, Luboinski M, Asselain B, Julien JP, Weber B, Mauriac L, Petit JC, Kerbrat P, Malhaire JP, Vennin P, Leduc B, Van Tongelen K. Short-term versus lifelong adjuvant tamoxifen in early breast cancer (ebc): a randomized trial (tam-01) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A451.

Dermendjieva L, Antonov R, Golemanova E, Mihailova J, Nikolov M. Adjuvant antiestrogen therapy with tamoxifen (Nolvadex) in early breast cancer (EBC) [abstract]. Eur J Cancer 1998;34 Suppl 2:S4.

Dewar JA, Stewart HJ, MacDonald TM. Tamoxifen compliance in a clinical trial. Breast 1996;5(3):152-3.

Dignam JJ, Bryant J, Wieand HS, Fisher B, Wolmark N. Early stopping of a clinical trial when there is evidence of no treatment benefit: protocol b-14 of the national surgical adjuvant breast and bowel project. Control Clin Trials 1998;19(6):575-88. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9875837&dopt;=Abstract

Earl H, Baker P, Kerr D, Lee M, Gray R, Baum M. Adjuvant treatment with tamoxifen. Recruitment into studies assessing optimum duration of treatment must continue [letter]. BMJ 1996 Apr 20;312(7037):1036-7. Comment on: BMJ 1996 Feb 17;312(7028):389-90. Comment in: BMJ 1996 Aug 24;313(7055):493-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8616358&dopt;=Abstract

Earl H, Gray R, Kerr D, Lee M. The optimal duration of adjuvant tamoxifen treatment for breast cancer remains uncertain: Randomize into aTTom. Clin Oncol 1997;9(3):141-3.

Ellis PA, Saccani-Jotti G, Clarke R, Johnston SR, Anderson E, Howell A, A'Hern R, Salter J, Detre S, Nicholson R, Robertson J, Smith IE, Dowsett M. Induction of apoptosis by tamoxifen and ICI 182780 in primary breast cancer. Int J Cancer 1997 Aug 7;72(4):608-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9259399&dopt;=Abstract

Extermann M, Baducci L, Lyman GH. Optimal duration of adjuvant tamoxifen treatment in elderly breast cancer patients: Influence of age, comorbidities, and various effectiveness hypotheses on life-expectancy and cost. Breast Dis 1996;9(6):327-39.

Extermann M, Balducci L, Lyman GH. Prolonging adjuvant tamoxifen in elderly breast cancer patients: Influence of age, comorbidities and various effectiveness hypotheses on life expectancy and cost [abstract]. Breast Cancer Res Treat 1996;37 Suppl:97.

Ferguson AT, Davidson NE. Regulation of estrogen receptor alpha function in breast cancer. Crit Rev Oncog 1997;8(1):29-46. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9516085&dopt;=Abstract

Ferno M, St~al O, Baldetorp B, Hatschek T, Kallstrom AC, Malmstrom P, Nordenskjold B, Ryden S. Results of two or five years of adjuvant tamoxifen correlated to steroid receptor and S-phase levels. South Sweden Breast Cancer Group, and South-East Sweden Breast Cancer Group. Breast Cancer Res Treat 2000 Jan;59(1):69-76. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10752681&dopt;=Abstract

Fisher B. Highlights from recent national surgical adjuvant breast and bowel project studies in the treatment and prevention of breast cancer. CA Cancer J Clin 1999;49(3):159-77. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10445015&dopt;=Abstract

Fisher B, Dignam J, Bryant J, DeCillis A, Wickerham DL, Wolmark N, Costantino J, Redmond C, Fisher ER, Bowman DM, Deschenes L, Dimitrov NV, Margolese RG, Robidoux A, Shibata H, Terz J, Paterson AH, Feldman MI, Farrar W, Evans J, Lickley HL. Five versus more than five years of tamoxifen therapy for breast cancer patients with negative lymph nodes and estrogen receptor-positive tumors. J Natl Cancer Inst 1996 Nov 6;88(21):1529-42. Comment in: J Natl Cancer Inst 1996 Nov 6;88(21):1510-2; J Natl Cancer Inst 1997 Nov 5;89(21):1631-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8901851&dopt;=Abstract

Fisher B, Dignam J, Wieand S, Wolmark N, Wickerham DL. Duration of tamoxifen (tam) therapy for primary breast cancer: 5 vs 10 years (nsabp b-14) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A118.

Fisher BJ, Perera FE, Cooke AL, Opeitum A, Stitt L. Long-term follow-up of axillary node-positive breast cancer patients receiving adjuvant tamoxifen alone: patterns of recurrence. Int J Radiat Oncol Biol Phys 1998 Aug 1;42(1):117-23. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9747828&dopt;=Abstract

Forbes JF. The control of breast cancer: the role of tamoxifen. Semin Oncol 1997 Feb;24(1 Suppl 1):S1-5-S1-19. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9045316&dopt;=Abstract

Gams R. Phase III trials of toremifene vs tamoxifen. Oncology (Huntingt) 1997 May;11(5 Suppl 4):23-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9165503&dopt;=Abstract

Gelmann EP. Tamoxifen induction of apoptosis in estrogen receptor-negative cancers: new tricks for an old dog? [editorial]. J Natl Cancer Inst 1996 Mar 6;88(5):224-6. Comment on: J Natl Cancer Inst 1996 Mar 6;88(5):279-84. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8613997&dopt;=Abstract

Goodare H. Adjuvant treatment with tamoxifen. Clinicians must share knowledge with their patients more readily [letter]. BMJ 1996 Apr 20;312(7037):1037. Comment on: BMJ 1996 Feb 17;312(7028):389-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8616359&dopt;=Abstract

Greenspan EM. Tamoxifen for the prevention of breast cancer [letter]. Am J Med 1996 Jun;100(6):665. Comment on: Am J Med 1995 Aug;99(2):180-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8678089&dopt;=Abstract

Gundersen S, Hannisdal E, Soreide JA, Skarstein A, Varhaug JE. Adjuvant tamoxifen for pre- and postmenopausal women with estrogen receptor positive, node positive breast cancer: a randomized study. Breast Cancer Res Treat 1995;36(1):49-53. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7579506&dopt;=Abstract

Harvey JM, Clark GM, Osborne CK, Allred DC. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 1999 May;17(5):1474-81. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10334533&dopt;=Abstract

Heerdt AS, Borgen PI. Current status of tamoxifen use: An update for the surgical oncologist. J Surg Oncol 1999 Sep;72(1):42-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10477879&dopt;=Abstract

Houghton J, Mustacchi G, Fosser V, Milani S, Latteier J, Bates T, Baum M. Local progression of disease in elderly patients with breast cancer managed in trials of tamoxifen versus surgery plus tamoxifen: combined data from the 'greta' and 'crc' trials [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A2224.

Houghton J, Riley D, Baum M. Results from the NATO and CRC trials of adjuvant tamoxifen therapy. Contrib Oncol 1995;50:121-34.

Iglesias L, Gomez A, Moreno A, Montano A, Ruiz M, Calvo E, Pastor P, Noguer M, Barea JL, Moreno Noguei JA. Tamoxifen (T) vs tamoxifen + uracil-ptegafur (T + UFT) in the adjuvant treatment of postmenopausal women with node positive breast cancer [abstract]. Eur J Cancer 1999;35 Suppl 4:S207.

Jaiyesimi IA, Buzdar AU, Decker DA, Hortobagyi GN. Use of tamoxifen for breast cancer: twenty-eight years later. J Clin Oncol 1995 Feb;13(2):513-29. Comment in: J Clin Oncol 1995 Aug;13(8):2142. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7844613&dopt;=Abstract

Jordan VC. Tamoxifen: toxicities and drug resistance during the treatment and prevention of breast cancer. Annu Rev Pharmacol Toxicol 1995;35:195-211. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7598491&dopt;=Abstract

Jordan VC. Tamoxifen treatment for breast cancer: concept to gold standard. Oncology (Huntingt) 1997 Feb;11(2 Suppl 1):7-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9065921&dopt;=Abstract

Kerr DJ, Earl HH, Baker PG, Jevons CM, Lee MJ, Baum M, Mansel RE, George WD, McArdle CS, Spooner D, Gray R, Dunn J. ATTom-adjuvant tamoxifen treatment, offer more? [abstract]. Br J Cancer 1996;74 Suppl 28:4.

Klijn JG, Grondahl-Hansen J, Schmitt M, Kramer MD, Look M, Brunner N, Janicke F, Foekens JA. The predictive value of the urokinase system with respect to response to tamoxifen therapy in recurrent breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A72.

Lee KS, Plowman PN, Gilmore OJ, Gray R. Tamoxifen in breast conservation therapy. Int J Clin Pharmacol Ther 1995 May;33(5):281-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7655767&dopt;=Abstract

Lien EA, Anker G, Ueland PM. Pharmacokinetics of tamoxifen in premenopausal and postmenopausal women with breast cancer. J Steroid Biochem Mol Biol 1995 Nov;55(2):229-31. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7495702&dopt;=Abstract

Lonning E, Lien EA. Mechanisms of action of endocrine treatment in breast cancer. Crit Rev Oncol Hematol 1995 Nov;21(1-3):158-93. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8822501&dopt;=Abstract

Love RR, Olsen MR, Havighurst TC. Delayed adjuvant tamoxifen in postmenopausal women with axillary node-negative breast cancer: mortality over 10 years [letter]. J Natl Cancer Inst 1999 Jul 7;91(13):1167-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10393732&dopt;=Abstract

Machin D, Andersen KW. Randomized trial of two versus five years of adjuvant tamoxifen for postmenopausal early stage breast cancer [letter]. J Natl Cancer Inst 1997 May 7;89(9):659-60. Comment on: J Natl Cancer Inst 1996 Nov 6;88(21):1543-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9150193&dopt;=Abstract

Makris A, Powles TJ, Allred DC, Ashley S, Ormerod MG, Titley JC, Dowsett M. Changes in hormone receptors and proliferation markers in tamoxifen treated breast cancer patients and the relationship with response. Breast Cancer Res Treat 1998 Mar;48(1):11-20. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9541185&dopt;=Abstract

Merimsky O, Inbar M, Kovner F, Chaitchik S. Adjuvant tamoxifen: 5 year control of dormant disease? [letter]. Eur J Cancer 1996 Jan;32A(1):174. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8695228&dopt;=Abstract

National Cancer Institute (US). Clinical alert: adjuvant therapy of breast cancer -- tamoxifen update. Bethesda (MD): The Institute; 1995 Nov 30. 6 p.

New hope for prevention, treatment of breast cancer. Harv Health Lett 1998 Aug;23(10):6-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9723013&dopt;=Abstract

O'Regan R, Jordan VC, Gradishar WJ. Tamoxifen and contralateral breast cancer. J Am Coll Surg 1999 Jun;188(6):678-83. Comment in: J Am Coll Surg 1999 Jun;188(6):684. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10359362&dopt;=Abstract

Osborne CK. Drug therapy. Tamoxifen in the treatment of breast cancer. N Engl J Med 1998 Nov 26;339(22):1609-18.

Palda VA, Goel V, Sawka CA. The rise of tamoxifen: temporal and geographical trends of tamoxifen use in Ontario. Breast Cancer Res Treat 1997 Mar;43(1):33-41. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9065597&dopt;=Abstract

Panasci LC, Melnychuk D. Re: five versus more than five years of tamoxifen therapy for breast cancer patients with negative lymph nodes and estrogen receptor-positive tumors [letter]. J Natl Cancer Inst 1997 Nov 5;89(21):1631-2. Comment on: J Natl Cancer Inst 1996 Nov 6;88(21):1529-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9362168&dopt;=Abstract

Peto R. Five years of tamoxifen--or more? [editorial]. J Natl Cancer Inst 1996 Dec 18;88(24):1791-3. Comment on: J Natl Cancer Inst 1996 Nov 6;88(21):1571-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8961965&dopt;=Abstract

Pitot HC. The tamoxifen controversy--clinical chemopreventive agent and experimental carcinogen. Proc Soc Exp Biol Med 1995 Feb;208(2):139-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7831344&dopt;=Abstract

Powles TJ. Efficacy of tamoxifen as treatment of breast cancer. Semin Oncol 1997 Feb;24(1 Suppl 1):S1-48-S1-54. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9045315&dopt;=Abstract

Preliminary results from the cancer research campaign trial evaluating tamoxifen duration in women aged fifty years or older with breast cancer. Current Trials working Party of the Cancer Research Campaign Breast Cancer Trials Group. J Natl Cancer Inst 1996 Dec 18;88(24):1834-9. Published erratum appears in J Natl Cancer Inst 1997 Apr 16;89(8):590. Comment in: J Natl Cancer Inst 1996 Dec 18;88(24):1791-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8961973&dopt;=Abstract

Pribylova O, Petruzelka L, Bustova I, Siffnerova H, Kuuta M, Muller V, Hacklova M, Kohoutek M, Kysela T, Tajblova J. The comparative randomised study of adjuvant therapy of breast cancer patients with tamoxifen versus tamoxifen plus chemotherapy [abstract]. Eur J Cancer 1999;35 Suppl 4:S209.

Pujol P, Daures J P, Herman J, Rouanet P, Rochefort H, Maudelonde T. Neo-adjuvant treatment of breast cancer with tamoxifen: a preliminary retrospective study [abstract]. Breast Cancer Res Treat 1996;41(3):292.

Randomized trial of two versus five years of adjuvant tamoxifen for postmenopausal early stage breast cancer. Swedish Breast Cancer Cooperative Group. J Natl Cancer Inst 1996 Nov 6;88(21):1543-9. Comment in: J Natl Cancer Inst 1996 Nov 6;88(21):1510-2. Comment in: J Natl Cancer Inst 1997 May 7;89(9):659-60. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8901852&dopt;=Abstract

Rea D, Poole C, Gray R. Adjuvant tamoxifen: how long before we know how long? BMJ 1998 May 16;316(7143):1518-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9582148&dopt;=Abstract

Repetto L, Venturino A, Comandini D, Parodi S, Granetto C, Porcile G, Audisio RA, Rosso R. A loading dose of tamoxifen followed by a standard dose in frail older women with breast cancer is feasible and effective [letter]. J Am Geriatr Soc 2000 Mar;48(3):346-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10733071&dopt;=Abstract

Robert NJ. Clinical efficacy of tamoxifen. Oncology (Huntingt) 1997 Feb;11(2 Suppl 1):15-20. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9065922&dopt;=Abstract

Ross D, Whitehead M. Hormonal manipulation and gynaecological cancer: the tamoxifen dilemma. Curr Opin Obstet Gynecol 1995 Feb;7(1):63-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7742519&dopt;=Abstract

Rutqvist LE. Randomized trial of 2 versus 5 years of adjuvant tamoxifen in postmenopausal early-stage breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A171.

Sader C, Ingram D, Hastrich D. Management of breast cancer in the elderly by complete local excision and tamoxifen alone. Aust N Z J Surg 1999 Nov;69(11):790-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10553967&dopt;=Abstract

Saibara T, Ogawa Y, Onishi S. Tamoxifen in early breast cancer [letter]. Lancet 1998 Aug 1;352(9125):404. Comment on: Lancet 1998 May 16;351(9114):1451-67. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9717954&dopt;=Abstract

Samonigg H, Jakesz R, Hausmaninger H, Depisch D, Fridrik M, Stierer M, Steger G, Kolb R, Hofbauer F, Reiner G, Schmid M. Tamoxifen vs. Tamoxifen plus aminoglutethimide for stage i and ii receptor-positive postmenopausal node-negative or node-positive breast cancer patients: four-year results of a randomized trial of the austrian breast cancer study group (abcsg) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A253.

Sledge GW, Hortobagyi GN. What is the optimum duration of tamoxifen adjuvant therapy? Cancer Control 1997;4(3 Suppl 1):9-13.

Stewart HJ, Forrest AP, Everington D, McDonald CC, Dewar JA, Hawkins RA, Prescott RJ, George WD. Randomised comparison of 5 years of adjuvant tamoxifen with continuous therapy for operable breast cancer. The Scottish Cancer Trials Breast Group. Br J Cancer 1996 Jul;74(2):297-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8688340&dopt;=Abstract

Tamoxifen and beyond. Harv Womens Health Watch 1998 Jun;5(10):1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9663008&dopt;=Abstract

Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group. Lancet 1998 May 16;351(9114):1451-67. Comment in: Lancet 1998 Aug 1;352(9125):403; Lancet 1998 Aug 1;352(9125):403-4; Lancet 1998 Aug 1;352(9125):404; Lancet 1998 Aug 1;352(9125):404-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9605801&dopt;=Abstract

Tormey DC, Gray R, Falkson HC. Postchemotherapy adjuvant tamoxifen therapy beyond five years in patients with lymph node-positive breast cancer. Eastern Cooperative Oncology Group. J Natl Cancer Inst 1996 Dec 18;88(24):1828-33. Comment in: J Natl Cancer Inst 1996 Dec 18;88(24):1791-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8961972&dopt;=Abstract

van Zyl JA, Muller AG. Tumour excision plus continuous tamoxifen compared with modified radical mastectomy in patients over 70 years of age with operable breast cancer. J Surg Oncol 1995 Jul;59(3):151-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7609520&dopt;=Abstract

Vogel CL. Hormonal approaches to breast cancer treatment and prevention: an overview. Semin Oncol 1996 Aug;23(4 Suppl 9):2-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8824459&dopt;=Abstract

Wazer DE, Morr J, Erban JK, Schmid CH, Ruthazer R, Schmidt-Ullrich RK. The effects of postradiation treatment with tamoxifen on local control and cosmetic outcome in the conservatively treated breast. Cancer 1997 Aug 15;80(4):732-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9264357&dopt;=Abstract

Willsher PC, Robertson JF, Jackson L, Al-Hilaly M, Blamey RW. Investigation of primary tamoxifen therapy for elderly patients with operable breast cancer. Breast 1997;6(3):150-4.

Yeh S, Tan LR, O'Connell TX. Segmental mastectomy and tamoxifen alone provide adequate locoregional control of breast cancer in elderly women. Am Surg 1997 Oct;63(10):854-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9322656&dopt;=Abstract

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### 3b. Other

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Bajetta E, Zilembo N, Bichisao E. Aromatase inhibitors in the treatment of postmenopausal breast cancer. Drugs Aging 1999 Oct;15(4):271-83. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10582774&dopt;=Abstract

Bajetta E, Zilembo N, Noberasco C. Second-generation aromatase inhibitors. Tumori 1995 Mar-Apr;81(2):77-80. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7778222&dopt;=Abstract

Baum M. Current role of adjuvant hormone therapy in the management of early carcinoma of the breast [abstract]. Anticancer Drugs 1995;6 Suppl 2:40.

Baum M. Use of aromatase inhibitors in the adjuvant treatment of breast cancer. Endocr Relat Cancer 1999 Jun;6(2):231-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10731114&dopt;=Abstract

Bergh J, Bonneterre J, Illiger HJ, Murray R, Nortier J, Paridaens R, Rubens RD, Samonigg H, Van Zyl J. Vorozole (rivizor) versus aminoglutethimide (ag) in the treatment of postmenopausal breast cancer relapsing after tamoxifen [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A543.

Bilimoria MM, Jordan VC. Is it time to develop an optimal endocrine therapy for premenopausal patients with axillary node positive and negative breast cancer? Semin Surg Oncol 1996 Sep-Oct;12(5):339-45. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8873322&dopt;=Abstract

Blamey RW. The role of selective non-steroidal aromatase inhibitors in future treatment strategies. Oncology 1997;54 Suppl 2:27-31. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9394858&dopt;=Abstract

Bluming VA, Waisman JR, Dosik GM, Olsen GA, Rosenbloom BE, McAndrew P, Terpenning M, Decker RW, Klein JH, Mosher M Van Sco, Green LM, Masterson M, Beard DB, Vogel CL, While AG, Schain W. Hormone replacement therapy (hrt) in women with previously treated primary breast cancer. Update [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A471.

Boccardo F, Amoroso D, Iacobelli S, Irtelli L, Farris A, Mustacchi G, Mesiti M, Brema F, Pacini P, Cortesi E, Nardini P, Guida G, Langenaeken C. Clinical efficacy and endocrine activity of vorozole in postmenopausal breast cancer patients. Results of a multicentric phase II study. Ann Oncol 1997 Aug;8(8):745-50. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9332681&dopt;=Abstract

Bonnier P, Bessenay F, Sasco AJ, Beedassy B, Lejeune C, Romain S, Charpin C, Piana L, Martin PM. Impact of menopausal hormone-replacement therapy on clinical and laboratory characteristics of breast cancer. Int J Cancer 1998 Jun 19;79(3):278-82. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9645351&dopt;=Abstract

Brodie AM, Njar VC. Aromatase inhibitors and breast cancer. Semin Oncol 1996 Aug;23(4 Suppl 9):10-20. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8824460&dopt;=Abstract

Brodie AM, Njar VC. Aromatase inhibitors and their application in breast cancer treatment*. Steroids 2000 Apr;65(4):171-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10713305&dopt;=Abstract

Brodowicz T, Wiltschke C, Zielinski C. Recent advances in hormonal treatment of breast cancer. Onkologie 1998;21(5):429-33.

Buzdar AU, Hortobagyi G. Update on endocrine therapy for breast cancer. Clin Cancer Res 1998 Mar;4(3):527-34. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9533518&dopt;=Abstract

Castiglione-Gertsch M. New aromatase inhibitors: more selectivity, less toxicity, unfortunately, the same activity [editorial]. Eur J Cancer 1996 Mar;32A(3):393-5. Comment on: Eur J Cancer 1996 Mar;32A(3):404-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8814679&dopt;=Abstract

Cheung KL, Willsher PC, Pinder SE, Ellis IO, Elston CW, Nicholson RI, Blamey RW, Robertson JF. Predictors of response to second-line endocrine therapy for breast cancer. Breast Cancer Res Treat 1997 Sep;45(3):219-24. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9386865&dopt;=Abstract

Clarke M, Collins R, Davies C, Godwin J, Gray R, Peto R. Ovarian ablation in early breast cancer: Overview of the randomised trials. Lancet 1996;348(9036):1189-96. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8898035&dopt;=Abstract

Coombes RC. Aromatase inhibitors and their use in the adjuvant setting. Recent Results Cancer Res 1998;152:277-84. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928565&dopt;=Abstract

Coombes RC, Harper-Wynne C, Dowsett M. Aromatase inhibitors and their use in the sequential setting. Endocr Relat Cancer 1999 Jun;6(2):259-63. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10731118&dopt;=Abstract

Cummings SR, Eckert S, Krueger KA, Grady D, Powles TJ, Cauley JA, Norton L, Nickelsen T, Bjarnason NH, Morrow M, Lippman ME, Black D, Glusman JE, Costa A, Jordan VC. The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial. JAMA 1999 Jun 16;281(23):2189-97. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10376571&dopt;=Abstract

Davidson N, O'Neill A, Vukov A, Osborne CK, Martino S, White D, Abeloff MD. Effect of chemohormonal therapy in premenopausal, node (+), receptor (+) breast cancer: an eastern cooperative oncology group phase III intergroup trial (e5188, int-0101) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A249.

Davidson NE. Ovarian ablation as treatment for young women with breast cancer. J Natl Cancer Inst Monogr 1994;(16):95-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7528032&dopt;=Abstract

de Matteis A, Landi G, Nuzzo F, Labonia V, Rossi E, Perrone F, D'Aiuto G, Capasso I, Longo C, Pizzorusso M. Second malignancies after LH-RH analogues treatment for early breast cancer [abstract]. Eur J Cancer 1999;35 Suppl 4:S209.

Dixon JM, Love CD, Renshaw L, Bellamy C, Cameron DA, Miller WR, Leonard RC. Lessons from the use of aromatase inhibitors in the neoadjuvant setting. Endocr Relat Cancer 1999 Jun;6(2):227-30. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10731113&dopt;=Abstract

Dixon M, Renshaw L, Bellamy C, Cameron DA, Miller WR. 'arimidex' As neoadjuvant therapy causes large reductions in tumour volume in postmenopausal women with large operable breast cancers [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A345.

Dowsett M. Aromatase inhibitors come of age [editorial]. Ann Oncol 1997 Jul;8(7):631-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9296213&dopt;=Abstract

Dowsett M, Lonning PE. Anastrozole--a new generation in aromatase inhibition: clinical pharmacology. Oncology 1997;54 Suppl 2:11-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9394854&dopt;=Abstract

Focan C, Beauduin M, Salamon E, De Greve J, De Wasch G, Lobelle JP, Majois F, Tagnon A, Tytgat J, Van Belle S, Vandervellen R, Vindevoghel A. High-dose medroxyprogesterone acetate as adjuvant hormonotherapy in early breast cancer: 9 years results of a multicenter randomized trial. Contrib Oncol 1995;50:145-58.

Fukuda M, Watanabe H, Suda H, Shimizu T. Sequential changes in hormone levels in postmenopausal breast cancer patients under long-term treatment with an aromatase inhibitor. Breast Cancer Res Treat 1999;57(1):106.

Geisler J, Ekse D, Hosch S, Lonning PE. Influence of droloxifene (3-hydroxytamoxifen), 40 mg daily, on plasma gonadotrophins, sex hormone binding globulin and estrogen levels in postmenopausal breast cancer patients. J Steroid Biochem Mol Biol 1995 Nov;55(2):193-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7495698&dopt;=Abstract

Geisler J, Haarstad H, Gundersen S, Raabe N, Kvinnsland S, Lonning PE. Influence of treatment with the anti-oestrogen 3-hydroxytamoxifen (droloxifene) on plasma sex hormone levels in postmenopausal patients with breast cancer. J Endocrinol 1995 Aug;146(2):359-63. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7561649&dopt;=Abstract

Geisler J, King N, Dowsett M, Ottestad L, Lundgren S, Walton P, Kormeset PO, Lonning PE. Influence of anastrozole (Arimidex), a selective, non-steroidal aromatase inhibitor, on in vivo aromatisation and plasma oestrogen levels in postmenopausal women with breast cancer. Br J Cancer 1996 Oct;74(8):1286-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8883419&dopt;=Abstract

Goldhirsch A, Gelber RD. Endocrine therapies of breast cancer. Semin Oncol 1996 Aug;23(4):494-505. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8757275&dopt;=Abstract

Goss PE, Tye LM. Anastrozole: a new selective nonsteroidal aromatase inhibitor. Oncology (Huntingt) 1997 Nov;11(11):1697-703; discussion 1707-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9394367&dopt;=Abstract

Harnett AN, Canney P, Coombes RC, Focan C, Slater AJ, Beauduin JM, Cusumano P, Ten Haaft M, Kerr D, Oster W, et al. A randomized phase II trial of rogletimide in heavily pretreated breast cancer patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A388.

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Helle SI, Lundgren S, Geisler S, Ekse D, Holly JM, Lonning PE. Effects of treatment with megestrol acetate on the insulin-like growth factor system: time and dose dependency. Eur J Cancer 1999 Jul;35(7):1070-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10533450&dopt;=Abstract

Holli K. Adjuvant trials of toremifene vs tamoxifen: the European experience. Oncology (Huntingt) 1998 Mar;12(3 Suppl 5):23-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9556787&dopt;=Abstract

Holli K. Evolving role of toremifene in the adjuvant setting. Oncology (Huntingt) 1997 May;11(5 Suppl 4):48-51. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9165507&dopt;=Abstract

Houghton J. Adjuvant treatment of premenopausal breast cancer with Zoladex and tamoxifen: Results from randomised trials by the Cancer Research Campaign (CRC) Breast Cancer Trials Group, The Stockholm Breast Cancer Study Group, the South East Sweden Breast Cancer Group and Gruppo Interdisciplinare Valutazione Intervention Oncologia (GIVIO) [abstract]. Br J Cancer 1999;80 Suppl 2:11.

Howell A, Anderson E, Blamey R, Clarke RB, Dixon JM, Dowsett M, Johnston SR, Miller WR, Nicholson R, Robertson JF. The primary use of endocrine therapies. Recent Results Cancer Res 1998;152:227-44. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928561&dopt;=Abstract

Howell A, Downey S, Anderson E. New endocrine therapies for breast cancer. Eur J Cancer 1996 Apr;32A(4):576-88. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8695256&dopt;=Abstract

Howell T. New endocrine agents. Cancer Treat Rev 1997 Jul;23 Suppl 1:S49-57. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9377602&dopt;=Abstract

Iglesias L, Moreno A, Gomez A, Barea JL, Ruiz M, Pastor P, Calvo E, Montano A, Noguer M, Nogueira JA. Uracil-ptegafur (UFT) + prednimustine (P) as an oral adjuvant treatment for premenopausal women with node positive breast cancer [abstract]. Eur J Cancer 1999;35 Suppl 4:S212.

Ingle JN, Suman VJ, Jordan VC, Dowsett M. Combination hormonal therapy involving aromatase inhibitors in the management of women with breast cancer. Endocr Relat Cancer 1999 Jun;6(2):265-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10731119&dopt;=Abstract

Investigators involved in toremifene studies call it a potentially safer antiestrogen. Oncology (Huntingt) 1998 Mar;12(3):469. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9534197&dopt;=Abstract

Jakesz R, Hausmaninger H, Samonigg H, Kubista E, Depisch D, Fridrik M, Stierer M, Gnant M, Steger G, Kolb R, Jatzko G, Hofbauer F, Reiner G, Luschin-Ebengreuth G. Comparison of adjuvant therapy with tamoxifen and goserelin vs. Cmf in premenopausal stage i and ii hormone-responsive breast cancer patients: four-year results of austrian breast cancer study group (abcsg) trial 5 [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A250.

Jimenez-Gordo AM, de las Heras B, Zamora P, Espinosa E, Gonzalez-Baron M. Failure of goserelin ovarian ablation in premenopausal women with breast cancer: two case reports. Gynecol Oncol 2000 Jan;76(1):126-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10620455&dopt;=Abstract

Johannessen DC, Engan T, Di Salle E, Zurlo MG, Paolini J, Ornati G, Piscitelli G, Kvinnsland S, Lonning PE. Endocrine and clinical effects of exemestane (PNU 155971), a novel steroidal aromatase inhibitor, in postmenopausal breast cancer patients: a phase I study. Clin Cancer Res 1997 Jul;3(7):1101-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9815789&dopt;=Abstract

Johnson AE. Endocrine therapy in breast cancer [letter]. Lancet 1996 Mar 16;347(9003):761. Comment on: Lancet 1996 Jan 27;347(8996):260. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8602017&dopt;=Abstract

Jonat W. Luteinizing hormone-releasing hormone analogues--the rationale for adjuvant use in premenopausal women with early breast cancer. Br J Cancer 1998 Sep;78 Suppl 4:5-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9741781&dopt;=Abstract

Jonat W. Temporary ovarian ablation in pre-menopausal women with early breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A224.

Kaufmann M. Luteinizing hormone-releasing hormone analogues in early breast cancer: updated status of ongoing clinical trials. Br J Cancer 1998 Sep;78 Suppl 4:9-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9741782&dopt;=Abstract

Lauro L D, Vici P, Carpano S, Paoletti G, Giulia M Dell, Belli F, Gionfra T, Conti F, Lopez M. Hormonal treatment with antiandrogens in disseminated male breast carcinoma (mbc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A415.

Locker GY. Hormonal therapy of breast cancer. Cancer Treat Rev 1998 Jun;24(3):221-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9767736&dopt;=Abstract

Lonning PE. Aromatase inhibition for breast cancer treatment. Acta Oncol 1996;35 Suppl 5:38-43. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9142963&dopt;=Abstract

Lonning PE. Pharmacological profiles of exemestane and formestane, steroidal aromatase inhibitors used for treatment of postmenopausal breast cancer. Breast Cancer Res Treat 1998;49 Suppl 1:S45-52; discussion S73-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9797017&dopt;=Abstract

Lonning PE, Geisler J, Dowsett M. Pharmacological and clinical profile of anastrozole. Breast Cancer Res Treat 1998;49 Suppl 1:S53-7; discussion S73-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9797018&dopt;=Abstract

Lonning PE, Paridaens R, Thurlimann B, Piscitelli G, di Salle E. Exemestane experience in breast cancer treatment. J Steroid Biochem Mol Biol 1997 Apr;61(3-6):151-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9365185&dopt;=Abstract

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McClelland RA, Manning DL, Gee JM, Anderson E, Clarke R, Howell A, Dowsett M, Robertson JF, Blamey RW, Wakeling AE, Nicholson RI. Effects of short-term antiestrogen treatment of primary breast cancer on estrogen receptor mRNA and protein expression and on estrogen-regulated genes. Breast Cancer Res Treat 1996;41(1):31-41. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8932874&dopt;=Abstract

Michaud LB, Buzdar AU. Risks and benefits of aromatase inhibitors in postmenopausal breast cancer. Drug Saf 1999 Oct;21(4):297-309. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10514021&dopt;=Abstract

Miller WR. Aromatase and its inhibitors: new biology and clinical perspectives. Endocr Relat Cancer 1999 Jun;6(2):127-30. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10744462&dopt;=Abstract

Miller WR, Dixon JM, Telford J, Marson L, Bellamy C, Kurian K, MacFarlane L, Anderson TJ. Endocrine and anti-tumour effects in breast cancer patients treated neo-adjuvantly with the aromatase inhibitor, letrozole [abstract]. Br J Cancer 1999;80 Suppl 2:104.

Minckwitz G, von de Assen A, Conrad B, Diehl AC, Eiermann W, Gerber B, Hilfrich J, Jonat W, Kreienberg R, Maass H, Massinger-Biebl H, Schumacher M, Wallwiener D, Kaufmann M. Medical ovarian ablation versus polychemotherapy in premenopausal patients with node-negative, receptor positive breast cancer. The ongoing trial 'a-93' of the german adjuvant breast cancer study group (gabg) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A395.

Mouridsen HT. New endocrine agents in the treatment of breast cancer. Eur J Cancer 1995;31A(5):826-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7640069&dopt;=Abstract

Murphy B, Muss HB. Hormonal therapy of breast cancer: state of the art. Oncology (Huntingt) 1997 May;11(5 Suppl 4):7-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9165500&dopt;=Abstract

Muss HB, Perez EA, Sledge GW Jr, O'Shaughnessy J. New hormones for advanced breast cancer. Cancer Control 1999;6(5 Suppl):12-6.

New aromatase inhibitors for breast cancer. Drug Ther Bull 1997 Jul;35(7):55-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9282426&dopt;=Abstract

Nicholson RI, Gee JM, Bryant S, Francis AB, McClelland RA, Knowlden J, Wakeling AE, Osborne CK. Pure antiestrogens. The most important advance in the endocrine therapy of breast cancer since 1896. Ann N Y Acad Sci 1996 Apr 30;784:325-35. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8651581&dopt;=Abstract

Osborne CK. Aromatase inhibitors in relation to other forms of endocrine therapy for breast cancer. Endocr Relat Cancer 1999 Jun;6(2):271-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10731120&dopt;=Abstract

Ovarian ablation for early breast cancer. Early Breast Cancer Trialists' Collaborative Group. Cochrane Database Syst Rev 2000;(2):CD000485. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10796722&dopt;=Abstract

Paridaens R, Roy JA, Nooij M, Klijn J, Houston SJ, Beex LV, Vinholes J, Tomiak E, Van Vreckem A, Langenaeken C, Van Glabbeke M, Piccart MJ. Vorozole (Rivizor): an active and well tolerated new aromatase inhibitor for the treatment of advanced breast cancer patients with prior tamoxifen exposure. Investigational Drug Branch of the European Organization for Research and Treatment of Cancer (EORTC) Breast Cancer Cooperative Group. Anticancer Drugs 1998 Jan;9(1):29-35. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9491789&dopt;=Abstract

Potyka I, Fennessy M, Houghton J, Baum M, Odling-Smee W. Local irradiation reduces breast relapses in presence of systemic adjuvant therapy [abstract]. Br J Cancer 1997;76 Suppl 1:18.

Powles TJ. Prognostic impact of amenorrhoea after adjuvant chemotherapy [editorial]. Eur J Cancer 1998 Apr;34(5):603-5. Comment on: Eur J Cancer 1998 Apr;34(5):632-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9713261&dopt;=Abstract

Pritchard KI. GnRH analogues and ovarian ablation: their integration in the adjuvant strategy. Recent Results Cancer Res 1998;152:285-97. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928566&dopt;=Abstract

Pritchard KI. Ovarian ablation as adjuvant therapy for early-stage breast cancer. Cancer Treat Res 1998;94:158-80. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9587687&dopt;=Abstract

Proceedings of the International Symposium on Aromatase and its Inhibition: New Biology and Clinical Perspectives. Prague, Czech Republic. 3-6 September 1998. Endocr Relat Cancer 1999 Jun;6(2):127-333. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10744463&dopt;=Abstract

Ragaz J. Status of aromatase inhibitors in relation to other breast cancer treatment modalities. Endocr Relat Cancer 1999 Jun;6(2):277-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10731121&dopt;=Abstract

Ragaz J, Jackson SM, Le N, Plenderleith IH, Wilson K, Knowling M, Olivotto I, Basco V, Spinelli J, Coldman A. Can ovarian ablation improve outcome of stage i-ii premenopausal breast cancer patients (pbcp) with estrogen receptor (er) positive tumors treated with adjuvant chemotherapy (adj ct)? Long-term analysis of british columbia (bc) randomized trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A501.

Robertson JF, Howell A, De Friend DJ, Blamey RW, Walton P. Duration of remission to ICI 182,780 compared to megestrol acetate in tamoxifen resistant breast cancer. Breast 1997;6(4):186-9.

Roy JA, Klijn J, Piccart MJ, Beex L, Mauriac L, Coleman R, Van Vreckem A, Langenaeken C. Phase II study of liarozole in advanced breast cancer patients: preliminary results [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A240.

Rubens RD. Aromatase inhibitors for breast cancer--further progress [editorial]. Eur J Cancer 1997 Jun;33(7):989-90. Comment on: Eur J Cancer 1997 Jun;33(7):1017-24. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9376202&dopt;=Abstract

Rutqvist L. Zoladex[trade] and tamoxifen as adjuvant therapy in premenopausal breast cancer: a randomised trial by the cancer research campaign (c. R. C.) Breast cancer trials group, the stockholm breast cancer study group, the south-east sweden breast cancer group & the gruppo interdisciplinare valutazione interventi in oncologia (g. I. V. I. O) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A251.

Saarto T, Blomqvist C, Ehnholm C, Taskinen MR, Elomaa I. Antiatherogenic effects of adjuvant antiestrogens: a randomized trial comparing the effects of tamoxifen and toremifene on plasma lipid levels in postmenopausal women with node-positive breast cancer. J Clin Oncol 1996 Feb;14(2):429-33. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8636753&dopt;=Abstract

Saarto T, Blomqvist C, Taskinen MR, Ehnholm C, Valimaki M, Makela P, Sarna S, Elomaa I. Effect of adjuvant toremifene, a novel antiestrogen, on bone mineral density and lipids in postmenopausal women with breast cancer [abstract]. Breast Cancer Res Treat 1997;46(1):31.

Santen RJ, Harvey HA. Use of aromatase inhibitors in breast carcinoma. Endocr Relat Cancer 1999 Mar;6(1):75-92. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10732791&dopt;=Abstract

Scott LJ, Wiseman LR. Exemestane. Drugs 1999 Oct;58(4):675-80; discussion 681-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10551437&dopt;=Abstract

Smith IE. Aromatase inhibitors: a dose-response effect? Endocr Relat Cancer 1999 Jun;6(2):245-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10731116&dopt;=Abstract

Smith IE. Pivotal trials of letrozole: a new aromatase inhibitor. Oncology (Huntingt) 1998 Mar;12(3 Suppl 5):41-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9556791&dopt;=Abstract

Thurlimann B. Hormonal treatment of breast cancer: new developments. Oncology 1998 Nov-Dec;55(6):501-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9778613&dopt;=Abstract

von Mensdorff-Pouilly S, Verstraeten AA, Kenemans P, Snijdewint FG, Kok A, Van Kamp GJ, Paul MA, Van Diest PJ, Meijer S, Hilgers J. Survival in early breast cancer patients is favorably influenced by a natural humoral immune response to polymorphic epithelial mucin. J Clin Oncol 2000 Feb;18(3):574-83. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10653872&dopt;=Abstract

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Williams GM. Re: In search of the perfect SERM: beyond tamoxifen and raloxifene [letter]. J Natl Cancer Inst 1998 Nov 4;90(21):1671. Comment on: J Natl Cancer Inst 1998 Jul 1;90(13):956-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9811319&dopt;=Abstract

Wiseman LR, Goa KL. Formestane. A review of its pharmacological properties and clinical efficacy in the treatment of postmenopausal breast cancer. Drugs Aging 1996 Oct;9(4):292-306. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8894526&dopt;=Abstract

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Zilembo N, Noberasco C, Bajetta E, Martinetti A, Mariani L, Orefice S, Buzzoni R, Di Bartolomeo M, Di Leo A, Laffranchi A, et al. Endocrinological and clinical evaluation of exemestane, a new steroidal aromatase inhibitor. Br J Cancer 1995 Oct;72(4):1007-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7547212&dopt;=Abstract

*Return to the top*

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## 4. Adjuvant Chemotherapy

### 4a. Indications

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Abrams JS. North American Adjuvant Breast Cancer Trials. Recent Results Cancer Res 1998;152:417-28. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928576&dopt;=Abstract

Adenis A, Vanlemmens L, Fournier C, Hecquet B, Bonneterre J. Mitoxantrone (dhad) and vinorelbine (vnr) as a primary treatment of locoregional breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A253.

Adjuvant systemic therapy for women with node-negative breast cancer. The Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer. CMAJ 1998 Feb 10;158 Suppl 3:S43-51. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9484278&dopt;=Abstract

Akerley WL 3rd. Contemporary adjuvant treatment of breast cancer. Surg Oncol Clin N Am 1995 Oct;4(4):685-99. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8535905&dopt;=Abstract

Albain K, Green S, Osborne K, Cobau C, Levine E, Ingle J, Pritchard K, Schneider D, O'Sullivan J, Hess E, Martino S. Tamoxifen (t) versus cyclophosphamide, adriamycin and 5-fu plus either concurrent or sequential t in postmenopausal, receptor(+), node(+) breast cancer: a southwest oncology group phase III intergroup trial (swog-8814, int-0100) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A450.

Allum WH, Smith IE. Carcinoma of the breast. Br J Hosp Med 1995 Sep 20-Oct 3;54(6):255-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8542173&dopt;=Abstract

Amano S, Kurosu Y, Hata S, Miyake H, Shibata M, Fujisaki S, Iwase M. Efficacy of adjuvant chemotherapy for breast cancer. Nihon Univ J Med 1997;39(2):93-101.

Anand A, Anand N, Anand A. Comment: adjuvant therapy decisions in node-negative breast cancer [letter]. Ann Pharmacother 1995 Sep;29(9):940-1. Comment on: Ann Pharmacother 1995 Mar;29(3):289-98. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8547753&dopt;=Abstract

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Pritchard KI. International St. Gallen conference: adjuvant therapy of primary breast cancer, February 25-28, 1998. Curr Oncol 1998;5(2):80-4.

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Ravdin PM, Siminoff LA, Harvey JA. Survey of American women who have received adjuvant chemotherapy [abstract]. Breast Cancer Res Treat 1996;41(3):219.

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Sawka C, Olivotto I, Coldman A, Goel V, Holowaty E, Hislop TG. The association between population-based treatment guidelines and adjuvant therapy for node-negative breast cancer. British Columbia/Ontario Working Group. Br J Cancer 1997;75(10):1534-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9166950&dopt;=Abstract

Sawka C, Olivotto I, Hislop G, Goel V, Holowaty E, Coldman A. Adjuvant systemic therapy (AST) for axillary lymph node negative breast cancer (NNBC) in British Columbia (BC) and Ontario (ON): impact of practice guidelines on consistency of care [abstract]. Clin Invest Med 1995;18(4 Suppl):B89.

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Watanabe T. Phase III randomized comparison of postoperative adjuvant chemotherapy with 2-year oral uracil/tegafur versus 6-cycle cyclophosphamide/methotrexate/5-fluorouracil in high-risk node-negative breast cancer patients. Cancer Chemother Pharmacol 1998;42 Suppl:S68-70. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9750032&dopt;=Abstract

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Yildirim E, Turhan N, Pak I, Berberoglu U. Secretory breast carcinoma in a boy. Eur J Surg Oncol 1999 Feb;25(1):98-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10188866&dopt;=Abstract

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### 4b. Specific Regimens

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Abeloff MD, Beveridge RA, Donehower RC, Fetting JH, Davidson NE, Gordon GG, Waterfield WC, Damron DJ. Sixteen-week dose-intense chemotherapy in the adjuvant treatment of breast cancer. J Natl Cancer Inst 1990 Apr 4;82(7):570-4. Comment in: J Natl Cancer Inst 1990 Apr 4;82(7):542-3; J Natl Cancer Inst 1990 Jul 18;82(14):1220-1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=2313733&dopt;=Abstract

Abeloff MD, Beveridge RA, Donehower RC, Fetting JH, Davidson NE, Gordon GG, Waterfield WC, Damron DJ. Sixteen-week, dose-intense chemotherapy in adjuvant treatment of breast cancer [reply]. J Natl Cancer Inst 1990 Jul 18;82(14):1220-1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=2362293&dopt;=Abstract

Adjuvant chemotherapy of breast cancer with 4 cycles of cyclophosphamide, methotrexate and 5-fluorouracil (cmf) versus 4 cycles of doxorubicin and cyclophosphamide (ac) in equitoxic regimen. The comparative multicentric study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A376.

Albain K, Green S, Osborne K, Cobau C, Levine E, Ingle J, Pritchard K, Schneider D, O'Sullivan J, Hess E, Martino S. Tamoxifen (t) versus cyclophosphamide, adriamycin and 5-fu plus either concurrent or sequential t in postmenopausal, receptor(+), node(+) breast cancer: a southwest oncology group phase III intergroup trial (swog-8814, int-0100) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A450.

Almenarez J, Molano F, Garcia I, Vega V, Diaz J M, Chirino R, Diaz-Chico JC, Murias A. FEC plus CEP versus FEC as adjuvant therapy on high-risk primary breast cancer patients [abstract]. Breast Cancer Res Treat 1999;57(1):49.

Alvarez A, Mickiewicz E, Caceres V, Ezcurdia L, Piris N, Brosio C, Giglio R, Cinat G. Vinorelbine (nvb) activity in heavily pretreated breast cancer (bc) patients (pts) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A250.

Anderson A, Cameron D A, Massie C, Dillon P, Leonard RCF. A single centre experience of adjuvant doxorubicin-CMF chemotherapy for multiple node positive breast cancer [abstract]. Eur J Cancer 1999;35 Suppl 4:S212.

Andersson M, Kamby C, Jensen MB, Mouridsen H, Ejlertsen B, Dombernowsky P, Rose C, Cold S, Overgaard M, Andersen J, Kjaer M. Tamoxifen in high-risk premenopausal women with primary breast cancer receiving adjuvant chemotherapy. Report from the Danish Breast Cancer co-operative Group DBCG 82B Trial. Eur J Cancer 1999 Nov;35(12):1659-66. Comment in: Eur J Cancer 1999 Nov;35(12):1625-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10674010&dopt;=Abstract

Antoine E, Meric JB, Coeffic D, Khallel N, Auclerc G, Nizri D, Delgado M, Rocher MA, Weil M, Merle S, Khayat D. Anthracycline-primary resistant breast cancer (aprbc): confirmatory results of the high level of activity of the docetaxel (d)-cisplatin (c) regimen [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A491.

Atkins CD. Adjuvant chemotherapy with CEF versus CMF for node-positive breast cancer [letter]. J Clin Oncol 1998 Dec;16(12):3916-7. Comment on: J Clin Oncol 1998 Aug;16(8):2651-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9850039&dopt;=Abstract

Baba H, Fukutomi T, Akashi S, Nanasawa T, Yamamoto H. Adjuvant cyclophosphamide, methotrexate and 5-fluorouracil versus cyclophosphamide plus futraful for premenopausal patients with stage I-II and one- to three-node-positive breast cancer: results of a prospective randomized study. Keio J Med 1996 Mar;45(1):54-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8882469&dopt;=Abstract

Batey MA, Wright JG, Simmonds D, Proctor M, Chapman F, Fishwick K, Azzabi A, Newell DR, Lind MJ, Calvert AH, Boddy AV. Population pharmacokinetics of CMF in the adjuvant treatment of breast cancer [abstract]. Br J Cancer 1999;80 Suppl 2:93.

Bergh J, Wiklund T, Erikstein B, Fornander T, Bengtsson NO, Malmstrom P, Kellokumpu-Lehtinen P, Anker G, Bennmarker H, Wilking N. Dosage of adjuvant G-CSF (filgrastim)-supported FEC polychemotherapy based on equivalent haematological toxicity in high-risk breast cancer patients. Scandinavian Breast Group, Study SBG 9401. Ann Oncol 1998 Apr;9(4):403-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9636831&dopt;=Abstract

Biganzoli L, Piccart MJ. The bigger the better? ... or what we know and what we still need to learn about anthracycline dose per course, dose density and cumulative dose in the treatment of breast cancer [editorial]. Ann Oncol 1997 Dec;8(12):1177-82. Comment in: Ann Oncol 1998 Apr;9(4):461. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9496381&dopt;=Abstract

Bisagni G, Cocconi G, Algeri R, Contu A, Fosser V, Blasio B D, Costanzo F D, Failla G, Palma M Dell, Gebbia V, Palmeri S, Sabbatini R, Borrini A, Camisa R. Cmf vs a sequential cisplatin/anthracycline containing regimen as adjuvant chemotherapy (ct) in stage ii breast carcinoma (bc) with >=10 involved axillary nodes. A prospective randomized study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A447.

Boccardo F, Rubagotti A, Amoroso D, Mesiti M, Pacini P, Gallo L, Sismondi P, Giai M, Genta F, Mustacchi G, Agostara B, Bolognesi A, Villa E, Schieppati G, Ausili Cefaro GP, Bellantone R, Farris A, Sassi M, Patrone F. Italian Breast Cancer Adjuvant Chemo-Hormone Therapy Cooperative Group Trials. GROCTA Trials. Recent Results Cancer Res 1998;152:453-70. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928580&dopt;=Abstract

Boccardo F, Rubagotti A, Amoroso D, Perrotta A, Sismondi P, Farris A, Mesiti M, Gallo L, Pacini P, Villa E, Agostara B. Lack of effectiveness of adjuvant alternating chemotherapy in node-positive, estrogen-receptor-negative premenopausal breast cancer patients: results of a multicentric Italian study. The Breast Cancer Adjuvant Chemo-Hormone Therapy Cooperative Group (GROCTA). Cancer Invest 1997;15(6):505-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9412655&dopt;=Abstract

Boddy AV, Batey MA, Wright JG, Simmonds D, Proctor M, Chapman F, Fishwick K, Azabi A, Newell DR, Lind MJ, Calvert AH. Inter- and intra-individual variation in the pharmacokinetics of cyclophosphamide, methotrexate and 5-fluorouracil in adjuvant treatment of breast cancer. Proc Am Assoc Cancer Res Annu Meet 1999;40:205-6.

Boehm DK, Maksymiuk AW. Paclitaxel premedication regimens [letter]. J Natl Cancer Inst 1996 Apr 3;88(7):463-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8618242&dopt;=Abstract

Bonadonna G, Valagussa P, Moliterni A, Zambetti M, Brambilla C. Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer: the results of 20 years of follow-up. N Engl J Med 1995 Apr 6;332(14):901-6. Comment in: N Engl J Med 1995 Apr 6;332(14):951-2; N Engl J Med 1995 Aug 31;333(9):596; discussion 597. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7877646&dopt;=Abstract

Bonadonna G, Valagussa P, Moliterni A, Zambetti M, Terenziani M, Ferrari L, Brambilla C. Update of the Milan Cancer Institute studies in operable breast cancer. Adjuv Ther Cancer 1997;8:77-82.

Bonneterre J, Roche H, Bremond A, Kerbrat P, Namer M, Fumoleau P, Goudier M-, Fargeot P, Bardonnet M, Marcillac I, Luporsi E. Results of a randomized trial of adjuvant chemotherapy with fec 50 vs fec 100 in high risk node-positive breast cancer patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A473.

Bosnjak S, Neskovic-Konstantinovic Z, Susnjar S, Mitrovic L, Radulovic S. Received dose intensity and outcome in adjuvant CMF chemotherapy of stage II breast cancer [abstract]. Therapie (Paris) 1995 Suppl;273.

Bottini A, Berruti A, Bersiga A, Brunelli A, Brizzi MP, Di Marco B, Cirillo F, Tampellini M, Bolsi G, Aguggini S, Betri E, Filippini L, Bertoli A, Alquati P, Dogliotti L. Cytotoxic and antiproliferative activity of the CMF regimen administered in association with tamoxifen as primary chemotherapy in breast cancer patients. Int J Oncol 1998 Aug;13(2):385-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9664137&dopt;=Abstract

Breier S, Lebedinsky C, Pelayes L, Traine G, Roffe C. Phase I/II weekly paclitaxel (p) 80 mg/m2 in pretreated patients (pts) with breast (bc) and ovarian cancer (oc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A568.

Broun ER, Petruska PJ, Dunphy FR, Velasquez WV, Pincus S, McIntyre W, Broun GO Jr. Taxol plus carboplatin/cyclophosphamide and peripheral blood stem cell (pbsc) support in stage ii/iii breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A1002.

Browne VW, Buzdar AU, Smith TL, McNeese M, Strom E, Dye C, Hortobagyi GN. The incidence of second primary breast cancer (spbc) in women treated with chemotherapy alone versus women treated with doxorubicin-containing chemotherapy (fac) and radiotherapy (xrt) [abstract]. Breast Cancer Res Treat 1996;37 Suppl:36.

Budd GT, Green S, O'Bryan RM, Martino S, Abeloff MD, Rinehart JJ, Hahn R, Harris J, Tormey D, O'Sullivan J, et al. Short-course FAC-M versus 1 year of CMFVP in node-positive, hormone receptor-negative breast cancer: an intergroup study. J Clin Oncol 1995 Apr;13(4):831-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7707108&dopt;=Abstract

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Buzdar A, Hortobagyi G, Wasaff B, Holmes F, Theriault R, Fraschini G, McNeese M, Singletary E. Combined modality approach (cma) for inflammatory carcinoma of breast (ibc): 20-year experience of m.d. Anderson cancer center [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A67.

Buzdar AU, Hortobagyi GN, Asmar L, Theriault RL, Rahman Z, McNeese M, Singletary S, Ames F. Prospective randomized trial of paclitaxel alone versus 5-fluorouracil/doxorubicin/cyclophosphamide as induction therapy in patients with operable breast cancer. Semin Oncol 1997 Oct;24(5 Suppl 17):S17-31-S17-34. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9374089&dopt;=Abstract

Buzdar AU, Hortobagyi GN, Singletary S, Theriault R, Booser D, Asmar L, McNeese M, Strom E, Ames F. Long-term efficacy data of fac-adjuvant therapy in breast cancer-a single institution's experience [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A455.

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Canavese G, Catturich A, Vecchio C, Gipponi M, Tomei D, Sertoli MR, Repetto L, Badellino F. Surgical complications related to peri-operative adjuvant chemotherapy in breast cancer. Results of a prospective, controlled, randomized clinical trial. Eur J Surg Oncol 1997 Feb;23(1):10-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9066740&dopt;=Abstract

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Castiglione-Gertsch M, Goldhirsch A, Gusterson B, Bettelheim R, Reed R, Gussett H, Geiser K, Hurny C, Bernhard J, Hangartner A, Maibach R, Pedowski R, Gelber R, Price K, Peterson H, Zelen M, Isley M, Hinkle R, Kay RG, et al. Duration and reintroduction of adjuvant chemotherapy for node-positive premenopausal breast cancer patients. J Clin Oncol 1996;14(6):1885-94. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8656257&dopt;=Abstract

Castiglione-Gertsch M, Johnsen C, Goldhirsch A, Gelber RD, Rudenstam CM, Collins J, Lindtner J, Hacking A, Cortes-Funes H, Forbes J, Simpson J, Tattersall MHN, Brunner K, Cavalli F, Senn HJ. The international (Ludwig) Breast Cancer Study Group Trials I-IV: 15 years follow-up. Ann Oncol 1994;5(8):717-24. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7826904&dopt;=Abstract

Chacon R, Blajman C, Galvez C, Romero C, Acuna J, Coppola F, Castagnari A, Macchiavelli M, Rosembrock C, Albera C, et al. Adjuvant chemotherapy for premenopausal, stage ii, node-positive breast cancer patients (pronacam 87): first analysis. The pronacam group [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A162.

Chacon R, Romero Acuna L, Blajman C, Galvez C, Bruno M, Romero A, Chiessa G, Bader M, Schwan R, Albera C, Santarelli MT, Sousa Martinez F, Nadal J, Viniegra M. Less efficacy with alternating regimen as adjuvant chemotherapy in stage II node-positive breast cancer: results at 8 years (Pronacam 85). Br J Cancer 1997;76(4):545-50. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9275035&dopt;=Abstract

Chang J, Powles TJ, Ormerod M, Allred DC, Ashley SE, Osborne CK, Dowsett M. Induction of apoptosis and decrease in proliferation predict response to systemic chemotherapy in breast cancer patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A2353.

Charrier S, Chassagne J, Cure H, Bay JO, Communal Y, Portefaix G, Ferriere JP, Betail G, Plagne R, Chollet P. Mobilization of peripheral blood progenitor cells after induction chemotherapy (THP-doxorubicin-vinorelbine-cyclophosphamide-fluorouracil) and granulocyte colony-stimulating factor in breast cancer. Bone Marrow Transplant 1998 Nov;22(9):845-51. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9827811&dopt;=Abstract

Clahsen PC, van de Velde CJ, Welvaart K, van Driel OJ, Sylvester RJ. Ten-year results of a randomized trial evaluating prolonged low-dose adjuvant chemotherapy in node-positive breast cancer: a joint European Organization for Research and Treatment of Cancer-Dutch Breast Cancer Working Party Study. Cooperating Investigators. J Clin Oncol 1995 Jan;13(1):33-41. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7799039&dopt;=Abstract

Colleoni M, Orlando L, Nole F, Goldhirsch A. Introducing taxanes in the adjuvant treatment of breast cancer: Expectations and reality. Breast 2000;9(3):134-8.

Colleoni M, Price K, Castiglione-Gertsch M, Goldhirsch A, Coates A, Lindtner J, Collins J, Gelber RD, Thurlimann B, Rudenstam CM. Dose-response effect of adjuvant cyclophosphamide, methotrexate, 5-fluorouracil (CMF) in node-positive breast cancer. International Breast Cancer Study Group. Eur J Cancer 1998 Oct;34(11):1693-700. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9893654&dopt;=Abstract

Colozza M, Bisagni G, Mosconi AM, Gori S, Boni C, Rosa Bian A, Sabbatini R, Frassoldati A, Passalacqua R, Rodino C, Rondini E, Algeri R, Di Sarra S, De Angelis V, Tonato M, Cocconi G. Lack of benefit of polychemotherapy (cmf) versus single-agent epirubicin (e) in the adjuvant treatment of breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A502.

Coombes RC, Bliss JM, Wils J, Morvan F, Espie M, Amadori D, Gambrosier P, Richards M, Aapro M, Villar-Grimalt A, McArdle C, Perez-Lopez FR, Vassilopoulos P, Ferreira EP, Chilvers CE, Coombes G, Woods EM, Marty M. Adjuvant cyclophosphamide, methotrexate, and fluorouracil versus fluorouracil, epirubicin, and cyclophosphamide chemotherapy in premenopausal women with axillary node-positive operable breast cancer: results of a randomized trial. The International Collaborative Cancer Group. J Clin Oncol 1996 Jan;14(1):35-45. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8558217&dopt;=Abstract

Cuvier C, Extra JM, Espie M, Cottu P, Marty M. Epirubicin 75 mg/m2 and cyclophosphamide 1200 mg/m2 every two weeks for stage ii breast cancer patients with more than four involved nodes [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A576.

Davidson N, Cheverton P, Campbell N, Davis AS. Film, an alternative chemotherapy regimen in the treatment of breast cancer [abstract]. Paper presented at: 6th International Congress on Anti-Cancer Treatment; 1996 Feb 6-9; Paris.

Davidson N, O'Neill A, Vukov A, Osborne CK, Martino S, White D, Abeloff MD. Effect of chemohormonal therapy in premenopausal, node (+), receptor (+) breast cancer: an eastern cooperative oncology group phase III intergroup trial (e5188, int-0101) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A249.

Davidson NG, Chick JB, Perren TJ, Campbell N, Thompson JM, Chan YT. A phase II study of single agent paclitaxel in patients at first relapse following initial chemotherapy for breast cancer. Clin Oncol (R Coll Radiol) 1996;8(6):358-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8973850&dopt;=Abstract

De Placido S, Perrone F, Carlomagno C, Morabito A, Pagliarulo C, Lauria R, Marinelli A, De Laurentiis M, Varriale E, Petrella G, et al. CMF vs alternating CMF/EV in the adjuvant treatment of operable breast cancer. A single centre randomised clinical trial (Naples GUN-3 study). Br J Cancer 1995 Jun;71(6):1283-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7779724&dopt;=Abstract

Delaloge S, Di Palma M, Bleuzen P, Chollet P, Fargeot P, Eicher F, Conroy T, Misset JL. A randomized phase III trial of an anthracycline-based chemotherapy with or without etretinate in the adjuvant treatment of hormonal receptors (hr)-negative breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A510.

Demicheli R, Miceli R, Brambilla C, Ferrari L, Moliterni A, Zambetti M, Valagussa P, Bonadonna G. Comparative analysis of breast cancer recurrence risk for patients receiving or not receiving adjuvant cyclophosphamide, methotrexate, fluorouracil (CMF). Data supporting the occurrence of 'cures'. Breast Cancer Res Treat 1999 Feb;53(3):209-15. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10369067&dopt;=Abstract

Di Blasio B, Cocconi G, Boni C, Bisagni G, Ceci G, Rondini E, Bella M, Leonardi F, Savoldi L, Buzzi P. Primary chemotherapy in operable breast carcinoma (bc). A prospective randomized trial comparing cmf with an anthracycline-containing regimen (cmfev) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A169.

Di Leo A, Crown J, Nogaret JM, Duffy K, Bartholomeus S, Dolci S, Rowan S, O'Higgins N, Paesmans M, Larsimont D, Riva A, Piccart MJ. A feasibility study evaluating docetaxel-based sequential and combination regimens in the adjuvant therapy of node-positive breast cancer. Ann Oncol 2000 Feb;11(2):169-75. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10761751&dopt;=Abstract

Di Leo A, Crown J, Nogaret JM, Duffy K, Bartholomeus S, Rowan S, O'Higgins N, Riva A, Piccart MJ. Sequential adriamycin (a), docetaxel (d) and cmf in the adjuvant treatment (at) of breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A582.

Dombernowsky P, Hansen PS, Mouridsen HT, Overgaard M, Rose C, Zedeler K. Randomized trial of adjuvant cmf + radiotherapy (rt) vs cmf alone vs + tamoxifen (tam) in pre- and menopausal stage ii breast cancer [abstract]. Ann Oncol 1994;5 Suppl 8:2.

Dubey A, Recht A, Come SE, Gelman RS, Silver B, Harris JR, Shulman LN. Concurrent CMF and radiation therapy for early stage breast cancer: results of a pilot study. Int J Radiat Oncol Biol Phys 1999 Nov 1;45(4):877-84. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10571193&dopt;=Abstract

Dumez H, Paridaens R, Lemmens J, Wildiers J, Christiaens R, Limbergen E Va, Bogaert W Van de, Vermeiren P, Oosterom AT. Predictors of dose and dose intensity in adjuvant cmf with or without concomitant radiotherapy in node positive breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A348.

Duration and reintroduction of adjuvant chemotherapy for node-positive premenopausal breast cancer patients. International Breast Cancer Study Group. J Clin Oncol 1996 Jun;14(6):1885-94. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8656257&dopt;=Abstract

Earl HM, Poole CJ, Spooner D, Jevons C, Dunn J. NEAT: A national breast cancer study of epirubicin+CMF vs classical CMF as adjuvant therapy [abstract]. Br J Cancer 1997;76 Suppl 1:24.

Ellerbroek NA. Sequencing of chemotherapy and radiation therapy in the treatment of early breast cancer: the devil is in the details [editorial]. Radiology 1996 Sep;200(3):605-7. Comment on: Radiology 1996 Sep;200(3):615-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8756900&dopt;=Abstract

Ellis GK, Green S, Livingston RB, Kraut MJ, Pierce HI, Paradelo JC, Taylor SA, Martino S. 'Neo-FAC' (5-fluorouracil, doxorubicin, and cyclophosphamide) for poor-prognosis stage IV breast cancer: a Southwest Oncology Group Phase II Study. Am J Clin Oncol 1999 Oct;22(5):446-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10521055&dopt;=Abstract

Faivre S, Braud AC, Bleuzen P, Extra JM, Espie M, Cottu PH, Maylin C, Cvitkovic E, Marty M. Influence of anthracyclines (a) in adjuvant chemotherapy (ct) regimens on site-specific and survival parameters in patients (pts) with breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A293.

Faris M, Abraham J, Barrett-Lee P. A patient with breast cancer and paraneoplastic cerebellar syndrome associated with anti-Purkinje cell antibodies: response to CMF chemotherapy. Clin Oncol (R Coll Radiol) 1998;10(3):202-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9704186&dopt;=Abstract

Ferriere JP, Charrier S, Cure H, Kwiatkowski F, Courtadon M, Belembaogo E, de Latour M, Achard JL, Dauplat J, Chollet P. Adjuvant chemotherapy with doxorubicin-containing regimen for 326 stage II breast cancers: 15-year results. Am J Clin Oncol 1997 Jun;20(3):219-25. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9167740&dopt;=Abstract

Fetting JH, Gray R, Fairclough DL, Smith TJ, Margolin KA, Citron ML, Grove-Conrad M, Cella D, Pandya K, Robert N, Henderson IC, Osborne CK, Abeloff MD. Sixteen-week multidrug regimen versus cyclophosphamide, doxorubicin, and fluorouracil as adjuvant therapy for node-positive, receptor-negative breast cancer: an Intergroup study. J Clin Oncol 1998 Jul;16(7):2382-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9667255&dopt;=Abstract

Fischer A, Hirshaut Y. Long-term follow-up of patients with stage ii breast cancer treated with cmfvp + tamoxifen [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A184.

Fisher B, Dignam J, DeCillis A, Wickerham DL, Wolmark N, Emir B, Dimitrov N, Abramson N, Atkins JN, Shibata H, Deschenes L. The worth of chemotherapy and tamoxifen (tam) over tam alone in node-negative patients with estrogen-receptor (er) positive invasive breast cancer (bc): first results from nsabp b-20 [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A1.

Fisher B, Dignam J, Mamounas EP, Costantino JP, Wickerham DL, Redmond C, Wolmark N, Dimitrov NV, Bowman DM, Glass AG, Atkins JN, Abramson N, Sutherland CM, Aron BS, Margolese RG. Sequential methotrexate and fluorouracil for the treatment of node-negative breast cancer patients with estrogen receptor-negative tumors: eight-year results from National Surgical Adjuvant Breast and Bowel Project (NSABP) B-13 and first report of findings from NSABP B-19 comparing methotrexate and fluorouracil with conventional cyclophosphamide, methotrexate, and fluorouracil. J Clin Oncol 1996 Jul;14(7):1982-92. Comment in: J Clin Oncol 1996 Jul;14(7):1971-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8683228&dopt;=Abstract

Fisher B, Dignam J, Wolmark N, DeCillis A, Emir B, Wickerham DL, Bryant J, Dimitrov NV, Abramson N, Atkins JN, Shibata H, Deschenes L, Margolese RG. Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer. J Natl Cancer Inst 1997 Nov 19;89(22):1673-82. Comment in: J Natl Cancer Inst 1997 Nov 19;89(22):1652-4; J Natl Cancer Inst 1998 Mar 18;90(6):468-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9390536&dopt;=Abstract

Fountzilas G, Polichronis A, Katsohis K, Gennatas K, Toussis D, Skarlos D, Kosmidis P, Vassilaros S, Semoglou C, Giannakakis T, Fahantidis E, Klouvas G, Tsavaris N, Konstantaras C, Makrantonakis P, Kolotas C, Zamboglou N, Tsiliakos S, Hainoglou D, Mylonakis N, Pavlidis N. Cyclophosphamide, mitoxantrone, fluorouracil versus conventional CMF as adjuvant treatment in node-positive breast cancer patients. A Hellenic Cooperative Oncology Group Study. Oncology 1996 Mar-Apr;53(2):137-46. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8604240&dopt;=Abstract

Ghavamzadeh A, Alimoghaddam K, Nasseri P, Dosti S. Comparison between CEF or CMF in adjuvant chemotherapy of breast cancer patients with more than three nodes positive [abstract]. Eur J Cancer 1999;35 Suppl 4:S328.

Glass JL, Frazee RC. Inflammatory breast cancer. Am Surg 1995 Feb;61(2):121-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7856970&dopt;=Abstract

Gold JE, Itzkowitz SH, Fan A, Reddish M, Stevens A, Longenecker BM. Vaccine-based (active specific) chemoimmunotherapy of relapsed or refractory breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A132.

Gold JE, Itzkowitz SH, Reddish M, Stevens A, Longenecker BM. Active specific chemoimmunotherapy of relapsed or refractory breast and gastrointestinal adenocarcinoma [abstract]. Proc Annu Meet Am Assoc Cancer Res 1995;36:A1329.

Goldhirsch A, Coates AS, Castiglione-Gertsch M, Gelber RD. New treatments for breast cancer: breakthroughs for patient care or just steps in the right direction? Ann Oncol 1998 Sep;9(9):973-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9818070&dopt;=Abstract

Goldhirsch A, Coates AS, Colleoni M, Castiglione-Gertsch M, Gelber RD. Adjuvant chemoendocrine therapy in postmenopausal breast cancer: cyclophosphamide, methotrexate, and fluorouracil dose and schedule may make a difference. International Breast Cancer Study Group. J Clin Oncol 1998 Apr;16(4):1358-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9552037&dopt;=Abstract

Goldhirsch A, Colleoni M, Coates AS, Castiglione-Gertsch M, Gelber RD. Adding adjuvant CMF chemotherapy to either radiotherapy or tamoxifen: are all CMFs alike? The International Breast Cancer Study Group (IBCSG). Ann Oncol 1998 May;9(5):489-93. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9653488&dopt;=Abstract

Gradishar WJ. Primary chemotherapy regimens and schedules. Semin Oncol 1998 Apr;25(2 Suppl 3):25-30. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9566204&dopt;=Abstract

Gradishar WJ, Loh K, Erban J, Vogel C, Grabelsky S, Cohen R, Limentani S, Woodard W, Dobbs T, Eisenberg P, Swain S. Preliminary results from a phase II study of (taxotere [t]) docetaxel as primary chemotherapy (pct) followed by doxorubicin (a) and cyclophosphamide (c) in stage III breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A599.

Hardman WE, Cameron IL, Knight C, Barnes CJ, Grant W. Dietary n-3 polyunsaturated fatty acids as an effective adjuvant to ET-18-OCH-3 (edelfosine) chemotherapy [abstract]. Proc Am Assoc Cancer Res Ann Meet 1996;37:387.

Hata Y, Uchino J, Asaishi K, Kubo Y, Mito M, Tanabe T, Ogita M, Hirata K. UFT and mitomycin plus tamoxifen for stage II, ER-positive breast cancer. Hokkaido ACETBC Study Group. Oncology (Huntingt) 1999 Jul;13(7 Suppl 3):91-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10442372&dopt;=Abstract

Henderson IC, Berry D, Demetri G, Cirrincione C, Goldstein L, Martino S, Ingle JN, Cooper MR, Canellos G, Borden E, Fleming G, Holland JF, Graziano S, Carpenter J, Muss H, Norton L. Improved disease-free (dfs) and overall survival (os) from the addition of sequential paclitaxel (t) but not from the escalation of doxorubicin (a) dose level in the adjuvant chemotherapy of patients (pts) with node-positive primary breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A390A.

Hery M, Sehraub S, Bonneterre J, Roche H, Luporsi E, Kerbrat P, Fumoleau P, Monnier A, Bardonnet-Comte M, Mercier M. Fasg-03: a randomized trial in node-negative breast cancer patients with bad prognostic factors. Study of an epirubicin-based adjuvant chemotherapy versus no systemic treatment [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A496.

Hillner BE, Ingle JN, Berenson JR, Janjan NA, Albain KS, Lipton A, Yee Gary, Biermann JS, Chlebowski RT, Pfister DG. American society of clinical oncology guideline on the role of bisphosphonates in breast cancer. J Clin Oncol 2000;18(6):1378-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10715310&dopt;=Abstract

Hirata K, Uchino J, Abe R, Nomura Y, Sugimachi K, Nakazato H, Abe O. Tegafur and uracil (UFT(R)) as post-operative adjuvant chemotherapy for breast cancer: Meta-analysis of five clinical studies [abstract]. Breast Cancer Res Treat 1999;57(1):47.

Hortobagyi GN. Paclitaxel-based combination chemotherapy for breast cancer . Oncology (Huntingt) 1997 Mar;11(3 Suppl 2):29-37. Published erratum appears in Oncology (Huntingt) 1997 Jul;11(7):943. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9110340&dopt;=Abstract

Hortobagyi GN. Recent progress in the clinical development of docetaxel (Taxotere). Semin Oncol 1999 Jun;26(3 Suppl 9):32-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10426457&dopt;=Abstract

Hortobagyi GN, Holmes FA. Single-agent paclitaxel for the treatment of breast cancer: an overview. Semin Oncol 1996 Feb;23(1 Suppl 1):4-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8629036&dopt;=Abstract

Hudis C, Seidman A, Raptis G, Currie V, Baselga J, Sklarin N, Moynahan M, Lebwohl D, Gilewski T, Fennelly D, et al. Sequential doxorubicin (a), paclitaxel (t), and cyclophosphamide (c) in women (pts) with resected breast cancer (bc) and greater than or equal to 4(+) lymph nodes (ln): preliminary results [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A152.

Hudis C, Seidman A, Raptis G, Fennelly D, Gilewski T, Baselga J, Theodoulou M, Sklarin N, Moynahan M, Surbone A, Currie V, Lebwohl D, Uhlenhopp M, Crown J, Norton L. Sequential adjuvant therapy: the Memorial Sloan-Kettering Cancer Center experience. Semin Oncol 1996 Feb;23(1 Suppl 1):58-64. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8629040&dopt;=Abstract

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Tormey DC, Gray R, Gilchrist K, Grage T, Carbone PP, Wolter J, Woll JE, Cummings FJ. Adjuvant chemohormonal therapy with cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (cmfp) or cmfp plus tamoxifen compared with cmf for premenopausal breast cancer patients. An Eastern Cooperative Oncology Group trial. Cancer 1990;65(2):200-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=2403834&dopt;=Abstract

Uglyanica KN, Fomin KA, Nefyodov LI, Nowicky JW, Brzosko WJ, Jankowski A. Influence of Ukrain on patients with surgically treated breast cancer. Part I. Clinical and laboratory parameters. Drugs Exp Clin Res 1996;22(3-5):135-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8899316&dopt;=Abstract

Uglyanica KN, Fomin KA, Nefyodov LI, Vilkiewich TW, Nowicky JW, Brzosko WJ, Jankowski A. Influence of Ukrain on patients with surgically treated breast cancer. Part II. Hormonal profile. Drugs Exp Clin Res 1996;22(3-5):139-41. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8899317&dopt;=Abstract

Uglyanica KN, Maciuk JR, Fomin KA, Nefyodov LI, Kravchuk RI, Vinogradova LM, Nowicky JW, Brzosko WJ. Influence of Ukrain on patients with surgically treated breast cancer. Part IV. Electromicroscopic and cytochemical evaluation. Drugs Exp Clin Res 1996;22(3-5):147-53. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8899319&dopt;=Abstract

Ung O, Langlands AO, Barraclough B, Boyages J. Combined chemotherapy and radiotherapy for patients with breast cancer and extensive nodal involvement. J Clin Oncol 1995 Feb;13(2):435-43. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7844606&dopt;=Abstract

Veronesi U, De Palo G, Marubini E, Costa A, Formelli F, Mariani L, Decensi A, Camerini T, Del Turco MR, Di Mauro MG, Muraca MG, Del Vecchio M, Pinto C, D'Aiuto G, Boni C, Campa T, Magni A, Miceli R, Perloff M, Malone WF, Sporn MB. Randomized trial of fenretinide to prevent second breast malignancy in women with early breast cancer. J Natl Cancer Inst 1999 Nov 3;91(21):1847-56. Comment in: J Natl Cancer Inst 1999 Nov 3;91(21):1794; J Natl Cancer Inst 2000 Feb 2;92(3):274; discussion 274-5; J Natl Cancer Inst 2000 Feb 2;92(3):274-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10547391&dopt;=Abstract

Volz J, Koester S, Fruehauf J. A phase II trial of docetaxel and epirubicin as adjuvant chemotherapy in patients with high-risk breast cancer [abstract]. Breast Cancer Res Treat 1999;57(1):48.

Vorgias G, Koukouras D, Tzoracoeleftherakis E, Androulakis J. Outcome of stage II breast cancer in Greece: a 10-year follow-up study. Med Sci Res 1998;26(5):313-6.

Watanabe T. Phase III randomized comparison of postoperative adjuvant chemotherapy with 2-year oral UFT (uracil/tegafur) versus six-cycle CMF (cyclophosphamide/methotrexate/5-fluorouracil) in high-risk node-negative breast cancer patients. Jpn J Clin Oncol 1998 Jan;28(1):77-80. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9491146&dopt;=Abstract

Wils JA, Bliss JM, Marty M, Coombes G, Fontaine C, Morvan F, Olmos T, Perez-Lopez FR, Vassilopoulos P, Woods E, Coombes RC. Epirubicin plus tamoxifen versus tamoxifen alone in node-positive postmenopausal patients with breast cancer: A randomized trial of the International Collaborative Cancer Group. J Clin Oncol 1999 Jul;17(7):1988-98. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10561249&dopt;=Abstract

Windsor S, Burtness B, Holsten B, DiStasio S, Staugaard-Hahn C, Farber L, Haffty B, Reiss M. Adjuvant sequential dose intense doxorubicin, paclitaxel and cyclophosphamide (atc) for high risk breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A705.

Yasumura T, Oka T, Koyama H, Kan N, Kobayashi T, Takatsuka Y, Noguchi M, Morimoto K, Miyakawa A, Suzuki T, Tobe T, Mori T. Five-year follow-up results of a randomized trial testing the role of epirubicin in node-positive breast cancer patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A711.

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### 4c. Pre-Operative Approaches

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Bassa P, Kim EE, Inoue T, Wong FC, Korkmaz M, Yang DJ, Wong WH, Hicks KW, Buzdar AU, Podoloff DA. Evaluation of preoperative chemotherapy using PET with fluorine-18-fluorodeoxyglucose in breast cancer. J Nucl Med 1996 Jun;37(6):931-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8683314&dopt;=Abstract

Bear HD. Indications for neoadjuvant chemotherapy for breast cancer. Semin Oncol 1998 Apr;25(2 Suppl 3):3-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9566201&dopt;=Abstract

Bellantone R, Lombardi CP, Cefaro GA, Nardone L, Rossi S, Minelli S, Raffaelli M, Crucitti F. CMF + radiotherapy in the primary treatment of operable breast cancer: preliminary results of a phase II pilot study. J Surg Oncol 1998 May;68(1):48-50. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9610663&dopt;=Abstract

Bernardo G, Plastina M, Bernardo A, Strada MR, Bottero G, Betta PG. Neoadjuvant chemotherapy (cyclophosphamide, epirubicin and fluorouracil) plus g-csf for operable breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A201.

Bhalla K, Harris WB. Molecular and biologic determinants of neoadjuvant chemotherapy of locoregional breast cancer. Semin Oncol 1998 Apr;25(2 Suppl 3):19-24. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9566203&dopt;=Abstract

Billgren AM, Rutqvist LE, Tani E, Wilking N, Fornander T, Skoog L. Proliferating fraction during neoadjuvant chemotherapy of primary breast cancer in relation to objective local response and relapse-free survival. Acta Oncol 1999;38(5):597-601. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10427948&dopt;=Abstract

Blohmer JU, Paepke S, Kissner L, Elling D, Fleige B, Grineisen Y, Lichtenegger W. Dose- intensified, preoperative and adjuvant chemotherapy in patients with T3- and T4- breast cancer: toxicity, clinical and pathological remission. Zentralbl Gynakol 1999;121(11):522-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10612219&dopt;=Abstract

Bonadonna G, Valagussa P. Primary chemotherapy in operable breast cancer. Semin Oncol 1996 Aug;23(4):464-74. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8757273&dopt;=Abstract

Booser D, Strom E, Singletary E, Holmes F, Hortobagyi G. Breast conservation (bc) following induction chemotherapy (ic) for t2-4,n1-2 breast carcinoma (labc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A260.

Booser DJ, Hortobagyi GN. Treatment of locally advanced breast cancer. Semin Oncol 1992;19(3):278-85. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1609294&dopt;=Abstract

Bottini A, Berruti A, Bersiga A, Brunelli A, Brizi MP, DiMarco B, Cirillo F, Bertoli G, Alquati P, Dogliotti L. Relationship between estrogen receptor status and antiproliferative effect of neoadjuvant chemotherapy in primary breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A110.

Bottini A, Berruti A, Bersiga A, Brunelli A, Brizzi MP, Marco BD, Cirillo F, Bolsi G, Bertoli G, Alquati P, Dogliotti L. Effect of neoadjuvant chemotherapy on Ki67 labelling index, c-erbB-2 expression and steroid hormone receptor status in human breast tumours. Anticancer Res 1996 Sep-Oct;16(5B):3105-10. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8920776&dopt;=Abstract

Bottini A, Berruti A, Tampellini M, Morrica B, Brunelli A, Gnocchi E, Brizzi MP, Aguggini S, Fara E, Alquati P, Dogliotti L. Influence of neoadjuvant chemotherapy on serum tumor markers CA 15-3, MCA, CEA, TPS and TPA in breast cancer patients with operable disease. Tumour Biol 1997;18(5):301-10. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9276030&dopt;=Abstract

Braud AC, Asselain B, Scholl S, De La Rochefordiere A, Palangie T, Dieras V, Pierga JY, Dorval T, Jouve M, Beuzeboc P, Pouillart P. Neoadjuvant chemotherapy in young breast cancer patients: correlation between response and relapse? Eur J Cancer 1999 Mar;35(3):392-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10448288&dopt;=Abstract

Bretz PD, Dreisbach PB. Using primary chemotherapy to treat invasive breast cancer without demonstrable metastases, to identify 'responders' in order to minimize or avoid surgery [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A569.

Briffod M, Tubiana-Hulin M, Spyratos F, Hacene K, Pallud C, Mayras C, Rouesse I. Fine-needle cytopunctures for early prediction of tumor response to preoperative chemotherapy in 94 operable breast carcinomas [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A261.

Broadwater JR, Edwards MJ, Kuglen C, Hortobagyi GN, Ames FC, Balch CM. Mastectomy following preoperative chemotherapy: Strict operative criteria control operative morbidity. Ann Surg 1991;213(2):126-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1992938&dopt;=Abstract

Buthiau D, Antoine E, Nizri D, Gozy M, Piette JC, Renody N, Weil M, Auclerc G, Rocher MA, Chevallier JM, Khayat D. Potential interest of MRI in the follow-up after conservative breast cancer treatment and in the evaluation of neoadjuvant chemotherapy. Ref Gynecol Obstet 1996;4(3):258-64.

Buzdar AU, Hortobagyi GN, Asmar L, Theriault RL, Rahman Z, McNeese M, Singletary S, Ames F. Prospective randomized trial of paclitaxel alone versus 5-fluorouracil/doxorubicin/cyclophosphamide as induction therapy in patients with operable breast cancer. Semin Oncol 1997;24(5 Suppl 17):S17-31-S17-34. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9374089&dopt;=Abstract

Buzdar AU, Hortobagyi GN, Theriault RL, Booser DJ, Valero VV, Ibrahim NI, Asmar L, Frye D, Manuel N, Kau S, McNeese M, Strom E, Hunt K, Singletary E, Ames F. Prospective randomized trial of taxol (tax) alone versus fluorouracil, doxorubicin, cyclophosphamide (fac) as an induction therapy in patients with operable breast cancer (br ca) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A273.

Buzdar AU, Singletary SE, Theriault RL, Booser DJ, Valero V, Ibrahim N, Smith TL, Asmar L, Frye D, Manuel N, Kau SW, McNeese M, Strom E, Hunt K, Ames F, Hortobagyi GN. Prospective evaluation of paclitaxel versus combination chemotherapy with fluorouracil, doxorubicin, and cyclophosphamide as neoadjuvant therapy in patients with operable breast cancer. J Clin Oncol 1999 Nov;17(11):3412-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10550135&dopt;=Abstract

Caleffi M, Borghetti KM, Duarte FD. Difficulties in monitoring treatment response during neo-adjuvant therapy. Is MRI an alternative? [abstract]. Breast Cancer Res Treat 1999;57(1):68.

Charrier S, Brain E, Cure H, van Praagh I, Feillel V, de Latour M, Dauplat J, Misset JL, Ferriere JP. Neoadjuvant chemotherapy in breast cancer. High pathological response rate induced by intensive anthracycline-based regimen [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A218.

Chevillard S, Vielh P, Pierga JY, Pouillart P. Mdr1 gene expression as predictive markers of clinical response in breast cancer treated by primary chemotherapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A41.

Chollet P, Bougnoux P, Amat S, Charrier S, Body G, Praagh I Va, Chevrier R, Dauplat J, Cure H. Induction chemotherapy in operable breast cancer: high pathological response rate induced by docetaxel [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A297.

Chollet P, Charrier S, Brain E, Cure H, van Praagh I, Feillel V, de Latour M, Dauplat J, Misset JL, Ferriere JP. Clinical and pathological response to primary chemotherapy in operable breast cancer. Eur J Cancer 1997 May;33(6):862-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9291806&dopt;=Abstract

Chollet P, Charrier S, Cure H, Brain E, van Praagh I, Feillel V, de Latour M, Dauplat J, Lipinski F, Misset JL, Ferriere JP. Neoadjuvant chemotherapy in operable breast cancer. High pathological response rate induced by vinorelbine-anthracycline-based regimen [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A573.

Clahsen P, van de Velde C, Goldhirsch A, Rossbach J, Sertoli M, Bijnens L, Sylvester R. An overview of randomized perioperative polychemotherapy trials in early breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A214.

Cocconi G, Guazzi A, Nizzoli R, Gardini G, Flora M, Di Blasio B, Moretti G, Savoldi L, Di Sarra S, Borrini A. Fine needle aspiration (fna) cytology assessment of biological parameters and relationship with response to primary chemotherapy (cr) in operable breast carcinoma (bc). A biological study parallel to a randomized clinical trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A46.

Colleoni M, Nole F, Minchella I, Noberasco C, Luini A, Orecchia R, Veronesi P, Zurrida S, Viale G, Goldhirsch A, Orecchia A/[corrected to Orecchia R]. Pre-operative chemotherapy and radiotherapy in breast cancer. Eur J Cancer 1998 Apr;34(5):641-5. Published erratum appears in Eur J Cancer 1999 Feb;35(2):328. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9713267&dopt;=Abstract

Colleoni M, Orvieto E, Nole F, Orlando L, Minchella I, Viale G, Peruzzotti G, Robertson C, Noberasco C, Galimberti V, Sacchini V, Veronesi P, Zurrida S, Orecchia R, Goldhirsch A. Prediction of response to primary chemotherapy for operable breast cancer. Eur J Cancer 1999 Apr;35(4):574-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10492630&dopt;=Abstract

Colozza M, Gori S, Mosconi AM, Anastasi P, De Angelis V, Giansanti M, Mercati U, Aristei C, Latini P, Tonato M. Induction chemotherapy with cisplatin, doxorubicin, and cyclophosphamide (CAP) in a combined modality approach for locally advanced and inflammatory breast cancer: Long-term results. Am J Clin Oncol 1996;19(1):10-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8554028&dopt;=Abstract

Costa SD, von Minckwitz G, Raab G, Blohmer JU, Dresel V, Eidtmann H, Hilfrich J, Jackisch C, Merkle E, Gademann G, Kaufmann M. The role of docetaxel (Taxotere) in neoadjuvant chemotherapy of breast cancer. Semin Oncol 1999 Jun;26(3 Suppl 9):24-31. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10426456&dopt;=Abstract

Curcillo PG 2nd, Schwartz GF, Komarnicky L, Topham A. Breast conservation following induction chemotherapy for stage ii carcinoma of the breast [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A575.

Daidone MG, Silvestrini R, Luisi A, Mastore M, Benini E, Veneroni S, Brambilla C, Ferrari L, Greco M, Andreola S, et al. Changes in biological markers after primary chemotherapy for breast cancers. Int J Cancer 1995 May 4;61(3):301-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7729938&dopt;=Abstract

Danforth D, Jacobson J, O'Shaughnessy J, Zujewski J, Riseberg D, Denicoff A, Noone M, Merino M, Steinberg S, Cowan K. Effect of preoperative chemotherapy on axillary lymph node metastases in stage ii breast cancer: a prospective randomized trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A213.

Danforth DN Jr, Zujewski J, O'Shaughnessy J, Riseberg D, Steinberg SM, McAtee N, Noone M, Chow C, Chaudhry U, Lippman M, Jacobson J, Okunieff P, Cowan KH. Selection of local therapy after neoadjuvant chemotherapy in patients with stage IIIA,B breast cancer. Ann Surg Oncol 1998 Mar;5(2):150-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9527268&dopt;=Abstract

Dash N, Chafin SH, Johnson RR, Contractor FM. Usefulness of tissue marker clips in patients undergoing neoadjuvant chemotherapy for breast cancer. AJR Am J Roentgenol 1999 Oct;173(4):911-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10511147&dopt;=Abstract

Dejager D, Redlich PN, Dayer AM, Davis HL, Komorowski RA. Primary squamous cell carcinoma of the breast: sensitivity to cisplatinum-based chemotherapy. J Surg Oncol 1995 Jul;59(3):199-203. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7609529&dopt;=Abstract

Eberlein TJ. Preoperative chemotherapy: where do we go from here? [editorial]. Ann Surg 1995 Nov;222(5):609-11. Comment on: Ann Surg 1995 Nov;222(5):612-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7487206&dopt;=Abstract

Elkhuizen PH, van Slooten HJ, Clahsen PC, Hermans J, van de Velde CJ, van den Broek LC, van de Vijver MJ. High local recurrence risk after breast-conserving therapy in node-negative premenopausal breast cancer patients is greatly reduced by one course of perioperative chemotherapy: A European Organization for Research and Treatment of Cancer Breast Cancer Cooperative Group Study. J Clin Oncol 2000 Mar;18(5):1075-83. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10694560&dopt;=Abstract

Ellis P, Smith I, Ashley S, Walsh G, Ebbs S, Baum M, Sacks N, McKinna J. Clinical prognostic and predictive factors for primary chemotherapy in operable breast cancer. J Clin Oncol 1998 Jan;16(1):107-14. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9440730&dopt;=Abstract

Ellis PA, Smith IE, Ashley S, Walsh G. Identification of factors predicting for clinical outcome following primary chemotherapy for operable breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A478.

Ellis PA, Smith IE, Detre S, Burton SA, Salter J, A'Hern R, Walsh G, Johnston SR, Dowsett M. Reduced apoptosis and proliferation and increased Bcl-2 in residual breast cancer following preoperative chemotherapy. Breast Cancer Res Treat 1998 Mar;48(2):107-16. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9596482&dopt;=Abstract

Ellis PA, Smith IE, McCarthy K, Detre S, Salter J, Dowsett M. Preoperative chemotherapy induces apoptosis in early breast cancer [letter]. Lancet 1997 Mar 22;349(9055):849. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9121265&dopt;=Abstract

Ellis PA, Smith IE, Salter J, Detre S, O'Brien ME, Ramage F, Dowsett M. Preoperative/neoadjuvant chemotherapy for early breast cancer induces apoptosis [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A112.

Epstein R. Treating breast cancer before surgery [editorial]. BMJ 1996 Nov 30;313(7069):1345-6. Comment in: BMJ 1997 Mar 8;314(7082):755. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8956687&dopt;=Abstract

Esteva FJ, Hortobagyi GN. Adjuvant systemic therapy for primary breast cancer. Surg Clin North Am 1999;79(5):1075-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10572552&dopt;=Abstract

Esteva FJ, Hortobagyi GN. Integration of systemic chemotherapy in the management of primary breast cancer. Oncologist 1998;3(5):300-3.

Ferriere JP, Assier I, Cure H, Charrier S, Kwiatkowski F, Achard JL, Dauplat J, Chollet P. Primary chemotherapy in breast cancer: correlation between tumor response and patient outcome. Am J Clin Oncol 1998 Apr;21(2):117-20. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9537193&dopt;=Abstract

Fetting J, Gray R, Abeloff M, Fowble B, Smith T, Vail S, Durrani G, Eudey L, Henney J, Margolin K, et al. Caf vs a 16-week multidrug regimen as adjuvant therapy for receptor-negative, node-positive breast cancer: an intergroup study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A83.

Fisher B, Brown A, Mamounas E, Wieand S, Fisher E, Robidoux A, Margolese R, Cruz A, Wickerham DL, Wolmark N. Effect of preoperative therapy for primary breast cancer (bc) on local-regional disease, disease-free survival (dfs) and survival (s): results from nsabp b-18 [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A449.

Fisher B, Brown A, Mamounas E, Wieand S, Robidoux A, Margolese RG, Cruz AB Jr, Fisher ER, Wickerham DL, Wolmark N, DeCillis A, Hoehn JL, Lees AW, Dimitrov NV. Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18. J Clin Oncol 1997 Jul;15(7):2483-93. Comment in: J Clin Oncol 1997 Jul;15(7):2479-82. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9215816&dopt;=Abstract

Fisher B, Bryant J, Wolmark N, Mamounas E, Brown A, Fisher ER, Wickerham DL, Begovic M, DeCillis A, Robidoux A, Margolese RG, Cruz AB Jr, Hoehn JL, Lees AW, Dimitrov NV, Bear HD. Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol 1998 Aug;16(8):2672-85. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9704717&dopt;=Abstract

Fisher B, Mamounas EP. Preoperative chemotherapy: a model for studying the biology and therapy of primary breast cancer [editorial]. J Clin Oncol 1995 Mar;13(3):537-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7884412&dopt;=Abstract

Fleming RY, Asmar L, Buzdar AU, McNeese MD, Ames FC, Ross MI, Singletary SE. Effectiveness of mastectomy by response to induction chemotherapy for control in inflammatory breast carcinoma. Ann Surg Oncol 1997 Sep;4(6):452-61. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9309333&dopt;=Abstract

Formenti SC, Symmans WF, Volm M, Skinner K, Cohen D, Spicer D, Danenberg PV. Concurrent paclitaxel and radiation therapy for breast cancer. Semin Radiat Oncol 1999 Apr;9(2 Suppl 1):34-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10210538&dopt;=Abstract

Furuya Y, Yamamoto K, Kohno N, Yamamoto M, Saitoh Y. Nocturnal 5-fluorouracil infusion to patients with breast cancer prior to surgery: appearance of 5-fluorouracil-induced AgNORs aggregation (FAA). Cancer Lett 1997 Jun 3;116(1):79-84. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9177461&dopt;=Abstract

Ganem G, Tubiana-Hulin M, Dieras V, Fumoleau P, Combe M, Misset JL, Bachelot T, Vannetzel JM, Boccara C. A phase II multicenter study evaluating the efficacy and the safety of a doxorubicine-docetaxel combination in neo-adjuvant treatment in patients (PTS) with an operable breast carcinoma (preliminary results) [abstract]. Breast Cancer Res Treat 1999;57(1):69.

Gazet JC, Coombes RC, Ford HT, Griffin M, Corbishley C, Makinde V, Lowndes S, Quilliam J, Sutcliffe R. Assessment of the effect of pretreatment with neoadjuvant therapy on primary breast cancer. Br J Cancer 1996;73(6):758-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8611376&dopt;=Abstract

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Ghilezan N, Vitoc C, Tanasscu R, Grecea D, Mihutiu S, Mihailov A, Rancea Ali, Muresan D, Rasinariu A, Todor N. Epidoxorubicin and paclitaxel combination in neoadjuvant setting for stage iib-iiia breast cancer. Preliminary results [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A354.

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Hortobagyi GN, Buzdar AU, Theriault RL, Valero V, Frye D, Booser DJ, Holmes FA, Giralt S, Khouri I, Andersson B, Gajewski JL, Rondon G, Smith TL, Singletary SE, Ames FC, Sneige N, Strom EA, McNeese MD, Deisseroth AB, Champlin RE. Randomized trial of high-dose chemotherapy and blood cell autografts for high-risk primary breast carcinoma. J Natl Cancer Inst 2000;92(3):225-33. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10655439&dopt;=Abstract

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Kuerer HM, Newman LA, Smith TL, Ames FC, Hunt KK, Dhingra K, Theriault RL, Singh G, Binkley SM, Sneige N, Buchholz TA, Ross MI, McNeese MD, Buzdar AU, Hortobagyi GN, Singletary SE. Clinical course of breast cancer patients with complete pathologic primary tumor and axillary lymph node response to doxorubicin-based neoadjuvant chemotherapy. J Clin Oncol 1999 Feb;17(2):460-9. Comment in: J Clin Oncol 1999 Feb;17(2):441-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10080586&dopt;=Abstract

Kuerer HM, Sahin AA, Hunt KK, Newman LA, Breslin TM, Ames FC, Ross MI, Buzdar AU, Hortobagyi GN, Singletary SE. Incidence and impact of documented eradication of breast cancer axillary lymph node metastases before surgery in patients treated with neoadjuvant chemotherapy. Ann Surg 1999 Jul;230(1):72-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10400039&dopt;=Abstract

Laing K, Ragaz J, Le N, Manji M, McLarden D, Yu S, Jackson S, Olivotto I, Gelmon K. Correlation of modified radical mastectomy (mrm) with outcome of stage iii breast cancer patients (siiibrca) treated with preoperative therapy (neo): is there a need for randomized trials? Analysis of the british columbia (bc) study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A647.

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Makris A, Powles TJ, Dowsett M, Osborne CK, Trott PA, Fernando IN, Ashley SE, Ormerod MG, Titley JC, Gregory RK, Allred DC. Prediction of response to neoadjuvant chemoendocrine therapy in primary breast carcinomas. Clin Cancer Res 1997 Apr;3(4):593-600. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9815725&dopt;=Abstract

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Mamounas EP. NSABP Protocol B-27. Preoperative doxorubicin plus cyclophosphamide followed by preoperative or postoperative docetaxel. Oncology (Huntingt) 1997 Jun;11(6 Suppl 6):37-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9213327&dopt;=Abstract

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Mamounas EP. Overview of National Surgical Adjuvant Breast Project neoadjuvant chemotherapy studies. Semin Oncol 1998 Apr;25(2 Suppl 3):31-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9566205&dopt;=Abstract

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Massidda B, Ionta MT, Pedditzi E, Foddi MR. Adjuvant therapy for high-risk (large size + 7-20 nodes) stage II and III breast cancer patients who received neoadjuvant [abstract]. Breast Cancer Res Treat 1996;37 Suppl:93.

Mauriac L, MacGrogan G, Avril A, Durand M, Floquet A, Debled M, Dilhuydy JM, Bonichon F. Neoadjuvant chemotherapy for operable breast carcinoma larger than 3 cm: a unicentre randomized trial with a 124-month median follow-up. Institut Bergonie Bordeaux Groupe Sein (IBBGS). Ann Oncol 1999 Jan;10(1):47-52. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10076721&dopt;=Abstract

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Minchella I, Colleoni M, Orvieto E, Nole F, Viale G, Fazio N, Sacchini V, Veronesi P, Orecchia R, Peruzzotti G, Goldhirsch A. Prediction of response to primary chemotherapy (pct) for operable breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A2114.

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Nistico C, Matteis A, Valenza R, Quattrocchio D, Garufi C, Cremonesi M, Rossi E, Agostara B, D'Ottavio AM, Lazzaro B, Borzacchini AM, Vaccaro A, Iodice F, Mencacci R, Terzoli E. Epirubicin (epi) and vinorelbine (vnr): a new promising combination for primary systemic chemotherapy for breast cancer patients (pts) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A622.

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Pouillart P, Fumoleau P, Romieu G, Tubiana-Hulin M, Namer M, Mauriac L, Guastalla JP, Pujade-Lauraine E, Kerbrat P, Maillart P, Quinaux E, Chazard M, Martinez A, Dieras V. Final results of a phase II randomized, parallel study of doxorubicin/cyclophosphamide (ac) and doxorubicin/taxol[trade] (paclitaxel) (at) as neoadjuvant treatment of local-regional breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A275.

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Sapunar F, Smith IE. Neoadjuvant chemotherapy for breast cancer. Ann Med 2000 Feb;32(1):43-50. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10711577&dopt;=Abstract

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Sharkey FE, Addington SL, Fowler LJ, Page CP, Cruz AB. Effects of preoperative chemotherapy on the morphology of resectable breast carcinoma. Mod Pathol 1996 Sep;9(9):893-900. Comment in: Mod Pathol 1997 Feb;10(2):155-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8878021&dopt;=Abstract

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Soubeyran I, Quenel N, Coindre JM, Bonichon F, Durand M, Wafflart J, Mauriac L. pS2 protein: a marker improving prediction of response to neoadjuvant tamoxifen in post-menopausal breast cancer patients. Br J Cancer 1996 Oct;74(7):1120-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8855985&dopt;=Abstract

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Valero V, Hoff PM, Singletary SE, Buzdar AU, Theriault RL, Strom E, Booser DJ, Asmar L, Frye D, McNeese MD, Hortobagyi GN. Combined modality treatment of locally advanced breast cancer (labc) in elderly patients (pts) using tamoxifen (tam) as primary therapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A403.

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von Minckwitz G, Costa SD, Eiermann W, Blohmer JU, Tulusan AH, Jackisch C, Kaufmann M. Maximized reduction of primary breast tumor size using preoperative chemotherapy with doxorubicin and docetaxel. J Clin Oncol 1999 Jul;17(7):1999-2005. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10561250&dopt;=Abstract

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Wolff AC, Davidson NE. Primary systemic therapy in operable breast cancer. J Clin Oncol 2000 Apr;18(7):1558-69. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10735905&dopt;=Abstract

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### 4d. Dose-Intense Approaches

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Abraham R, Nagy T, Goss PE, Crump M. High dose chemotherapy and autologous blood stem cell support in women with breast carcinoma and isolated supraclavicular lymph node metastases. Cancer 2000 Feb 15;88(4):790-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10679648&dopt;=Abstract

Adkins D, Brown R, Trinkaus K, Maziarz R, Luedke S, Freytes C, Needles B, Wienski D, Fracasso P, Pluard T, Moriconi W, Ryan T, Hoelzer K, Safdar S, Rearden T, Rodriguez G, Khoury H, Vij R, DiPersio J. Outcomes of high-dose chemotherapy and autologous stem-cell transplantation in stage IIIB inflammatory breast cancer. J Clin Oncol 1999 Jul;17(7):2006-14. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10561251&dopt;=Abstract

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Adomeit A, Frick M, Mohrmann S, Fischer J, Schwenkhagen A, Mezger J, Ziske C, Kleinschmidt R, Werner C, Eimermacher H, Ko J, Koch O, Bodden-Heidrich R, Daubel A, Bender HG, Nitz U. Tandem high-dose chemotherapy (hdc) versus dose-dense conventional chemotherapy for patients with high-risk breast cancer (hrbc)---interim results from a multicenter phase III trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A478.

Amorosa D, Boccardo F, Rubagotti A, Ballestrero A, Ferrando, Brema F, Genta F, Sismondi P, Sertoli MR, Rosso R, Folco U, Irtelli L, Iacobelli S, Mammoliti S, Mesiti M, Pacini P, Rinaldini M, Patrone F. Adjuvant high-dose chemotherapy (hd ct) without bone marrow rescue in breast cancer patients (bc pts) with 10 or more positive nodes: preliminary results of an italian breast cancer adjuvant study group (grocta) trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A505.

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Ando M, Yokozawa T, Sawada J, Takaue Y, Togitani K, Kawahigashi N, Narabayashi M, Takeyama K, Tanosaki R, Mineishi S, Kobayashi Y, Watanabe T, Adachi I, Tobinai K. Cardiac conduction abnormalities in patients with breast cancer undergoing high-dose chemotherapy and stem cell transplantation. Bone Marrow Transplant 2000 Jan;25(2):185-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10673678&dopt;=Abstract

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Antman KH, Rowlings PA, Vaughan WP, Pelz CJ, Fay JW, Fields KK, Freytes CO, Gale RP, Hillner BE, Holland HK, Kennedy MJ, Klein JP, Lazarus HM, McCarthy PL Jr, Saez R, Spitzer G, Stadtmauer EA, Williams SF, Wolff S, Sobocinski KA, Armitage JO, Horowitz MM. High-dose chemotherapy with autologous hematopoietic stem-cell support for breast cancer in North America. J Clin Oncol 1997 May;15(5):1870-9. Comment in: J Clin Oncol 1998 Feb;16(2):800-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9164197&dopt;=Abstract

Arat M, Demirer T, Ustun C, Celebi H, Tuzun A, Coskun H, Ayyyldyz E, Ylhan O, Gurman G, Ozcan M, Koc H. A phase I dose escalation study of high dose thiotepa, melphalan and carboplatin (tmc) followed by autologous peripheral blood stem cell transplantation in patients with high risk breast cancer and hematologic malignancies [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A207.

Arun B, Slack R, Gehan E, Spitzer T, Meehan KR. Survival after autologous hematopoietic stem cell transplantation for patients with inflammatory breast carcinoma. Cancer 1999 Jan 1;85(1):93-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9921979&dopt;=Abstract

Ayash LJ, Elias A, Ibrahim J, Schwartz G, Wheeler C, Reich E, Lynch C, Warren D, Shapiro C, Richardson P, Hurd D, Schnipper L, Frei E 3rd, Antman K. High-dose multimodality therapy with autologous stem-cell support for stage IIIB breast carcinoma. J Clin Oncol 1998 Mar;16(3):1000-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9508183&dopt;=Abstract

Azagra P, Perez-Ruixo JJ, Alberola V, Medina C, Jimenez NV, Garcia J. Population-pharmacokinetics (pk) study of high-dose cyclophosphamide (cpp) in a program of high dose chemotherapy (hdct) and peripheral blood stem cell (pbsc) transplantation in high risk (hr) breast cancer (bc) patients (pts) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A312.

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Ballestrero A, Ferrando F, Garuti A, Basta P, Gonella R, Esposito M, Vannozzi MO, Sorice G, Friedman D, Puglisi M, Brema F, Mela GS, Sessarego M, Patrone F. High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule. Br J Cancer 1997;76(6):797-804. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9310249&dopt;=Abstract

Ballestrero A, Ferrando F, Garuti A, Basta P, Gonella R, Stura P, Mela GS, Sessarego M, Gobbi M, Patrone F. Comparative effects of three cytokine regimens after high-dose cyclophosphamide: granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor (GM-CSF), and sequential interleukin-3 and GM-CSF. J Clin Oncol 1999 Apr;17(4):1296. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10561192&dopt;=Abstract

Barni S, Piazza E, Frontini L, Grittini A, Baroni M, Visini M, Gallotti P, Lucani G, Nosenzo A, Ardizzoia A, Villa S. Three year survival and relapse after neoadjuvant high-dose epidoxorubicin (epi) in stage ii-iiia breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A556.

Basser R, To LB, Kotasek D, Szer J, Bashford J, Durrant S, Begley G, Fox R, Collins J, Russell I, Keefe D, Maher D, Cebon J, Gill PG, Juttner C, Pitman K, Green M. Multicycle high-dose chemotherapy (ct) with peripheral blood progenitor cell (pbpc) support as adjuvant or initial treatment of high risk breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A488.

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Basser RL, To LB, Collins JP, Begley CG, Keefe D, Cebon J, Bashford J, Durrant S, Szer J, Kotasek D, Juttner CA, Russell I, Maher DW, Olver I, Sheridan WP, Fox RM, Green MD. Multicycle high-dose chemotherapy and filgrastim-mobilized peripheral-blood progenitor cells in women with high-risk stage II or III breast cancer: five-year follow-up. J Clin Oncol 1999 Jan;17(1):82-92. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10458221&dopt;=Abstract

Baynes RD, Dansey RD, Klein JL, Karanes C, Cassells L, Abella E, Wei WZ, Galy A, Du W, Wood G, Peters WP. High-dose chemotherapy and autologous stem cell transplantation for breast cancer. Cancer Invest 2000;18(5):440-55. Comment in: Cancer Invest 2000 ;18(5):494-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10834029&dopt;=Abstract

Bearman S, Vredenburgh J, Cagnoni P, Shpall E, Nieto Y, Ross M, Peters W, Jones R. High-dose therapy with autologous hematopoietic cell support as salvage treatment for patients with breast cancer who have relapsed after previous high-dose chemotherapy. Bone Marrow Transplant 1999 Sep;24(5):491-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10482932&dopt;=Abstract

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Bearman SI, Overmoyer BA, Bolwell BJ, Taylor CW, Shpall EJ, Cagnoni PJ, Mechling BE, Ronk B, Baron AE, Purdy MH, Ross M, Jones RB. High-dose chemotherapy with autologous peripheral blood progenitor cell support for primary breast cancer in patients with 4-9 involved axillary lymph nodes. Bone Marrow Transplant 1997 Dec;20(11):931-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9422471&dopt;=Abstract

Benedetti Panici P, Pierelli L, Scambia G, Foddai ML, Salerno MG, Menichella G, Vittori M, Maneschi F, Caracussi U, Serafini R, Leone G, Mancuso S. High-dose carboplatin, etoposide and melphalan (CEM) with peripheral blood progenitor cell support as late intensification for high-risk cancer: non-haematological, haematological toxicities and role of growth factor administration. Br J Cancer 1997;75(8):1205-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9099971&dopt;=Abstract

Bergh J. High dose chemotherapy in the adjuvant setting for high risk breast cancer patients: results from a randomized study [abstract]. Eur J Cancer 1999;35 Suppl 4:S219.

Bergh J. Is there a role for intensive therapy in breast cancer? Acta Oncol 1999;38 Suppl 13:37-46. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10612495&dopt;=Abstract

Bergh J. Where next with stem-cell-supported high-dose therapy for breast cancer? Lancet 2000 Mar 18;355(9208):944-5. Comment on: Lancet 2000 Mar 18;355(9208):999-1003. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10768427&dopt;=Abstract

Bezwoda WR. High dose chemotherapy with haematopoietic rescue in breast cancer. Hematol Cell Ther 1999 Apr;41(2):58-65. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10344553&dopt;=Abstract

Bezwoda WR. High-dose chemotherapy with hematopoietic rescue in breast cancer: from theory to practice. Cancer Chemother Pharmacol 1997;40 Suppl:S79-87. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9272140&dopt;=Abstract

Bitran JD, Samuels BL, Klein LM, Schroeder L, Martinec J, Harris E. Autologous bone marrow transplantation (abmt) for women with stage ii and iiia high risk (greater than 10 involved lymph nodes) breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A184.

Borges V, Joyce R, Kennedy L, Avigan D. Docetaxel and filgrastim: a promising stem cell mobilization regimen prior to high-dose chemotherapy for breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A210.

Brockstein BE, Smiley C, Al-Sadir J, Williams SF. Cardiac and pulmonary toxicity in patients undergoing high-dose chemotherapy for lymphoma and breast cancer: prognostic factors. Bone Marrow Transplant 2000 Apr;25(8):885-94. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10808211&dopt;=Abstract

Buchholz TA, Tucker SL, Moore RA, McNeese MD, Strom EA, Jhingrin A, Hortobagyi GN, Singletary SE, Champlin RE. Importance of radiation therapy for breast cancer patients treated with high-dose chemotherapy and stem cell transplant. Int J Radiat Oncol Biol Phys 2000;46(2):337-43. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10661340&dopt;=Abstract

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Burtness B, Distasio S, Orell J, Farber L, Haffty B, Reiss M. Adjuvant sequential dose intense doxorubicin, paclitaxel and cyclophosphamide for high risk breast cancer [abstract]. Breast Cancer Res Treat 1996;41(3):233.

Busse D, Bohnenstengel F, Eichelbaum M, Fischer P, Kroemer HK, Schumacher K, Schweizer E, Busch FW. Pharmacokinetics of cyclophosphamide during "conventional dose" and high dose adjuvant chemotherapy in patients with primary breast cancer [abstract]. Therapie (Paris) 1995 Suppl;274.

Busse D, Busch FW, Schweizer E, Bohnenstengel F, Eichelbaum M, Fischer P, Schumacher K, Aulitzky WE, Kroemer HK. Fractionated administration of high-dose cyclophosphamide: Influence on dose-dependent changes in pharmacokinetics and metabolism. Cancer Chemother Pharmacol 1999;43(3):263-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9923558&dopt;=Abstract

Buzdar AU, Hortobagyi GN, Kau SW, Smith TL, Fraschini G, Holmes FA, Gutterman JU, Hug VM, Singletary SE, Ames FC, et al. Adjuvant therapy with escalating doses of doxorubicin and cyclophosphamide with or without leukocyte alpha-interferon for stage ii or iii breast cancer. J Clin Oncol 1992;10(10):1540-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1403033&dopt;=Abstract

Cagnoni PJ, Jones RB, Franklin W, Hami L, Berenson RJ, Jacobs C, Ross M, Bearman SI, Shpall EJ. Use of cd34 positive autologous hematopoietic progenitors to support patients with breast cancer after high-dose chemotherapy [abstract]. Paper presented at: 6th International Congress on Anti-Cancer Treatment; 1996 Feb 6-9; Paris.

Cagnoni PJ, Nieto Y, Shpall EJ, Bearman SI, Baron AE, Ross M, Matthes S, Dunbar SE, Jones RB. High-dose chemotherapy with autologous hematopoietic progenitor-cell support as part of combined modality therapy in patients with inflammatory breast cancer. J Clin Oncol 1998 May;16(5):1661-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9586876&dopt;=Abstract

Cagnoni PJ, Shpall EJ. High-dose chemotherapy for the treatment of breast and ovarian cancer. Curr Opin Oncol 1997 Mar;9(2):122-5. Comment in: Curr Opin Oncol 1997 Mar;9(2):115-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9161788&dopt;=Abstract

Cagnoni PJ, Shpall EJ, Bearman SI, Ross M, Jones RB. High-dose chemotherapy with AHPCS for the treatment of breast cancer. The University of Colorado results. Bone Marrow Transplant 1996 Sep;18 Suppl 1:S26-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8899166&dopt;=Abstract

Cameron DA, Leonard RC. The case for high-dose adjuvant chemotherapy in breast cancer: (I) theoretical considerations. Eur J Surg Oncol 1996 Oct;22(5):540-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8903501&dopt;=Abstract

Cameron DA, Leonard RC. The case for high-dose adjuvant chemotherapy in breast cancer: (II) clinical experience. Eur J Surg Oncol 1996 Dec;22(6):634-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9005153&dopt;=Abstract

Canellos GP. Clinical research saves money: reflections on high-dose therapy of breast cancer [editorial]. J Clin Oncol 1999 Jul;17(7):1965-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10561244&dopt;=Abstract

Chabannon C, Blache JL, Sielleur I, Douville J, Faucher C, Gravis G, Arnoulet C, Oziel-Taieb S, Blaise D, Novakovitch G, Camerlo J, Chabbert I, Genre D, Appel M, Armstrong D, Maraninchi D, Viens P. Production of ex vivo expanded hematopoietic cells and progenitors in a closed bioreactor, starting with a small volume marrow collection: A feasibility study in patients with poor-risk breast cancer and receiving high-doses of cyclophosphamide. Int J Oncol 1999 Sep;15(3):511-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10427133&dopt;=Abstract

Chabannon C, Cornetta K, Lotz JP, Rosenfeld C, Shlomchik M, Yanovitch S, Marolleau JP, Sledge G, Novakovitch G, Srour EF, Burtness B, Camerlo J, Gravis G, Lee-Fischer J, Faucher C, Chabbert I, Krause D, Maraninchi D, Mills B, Kunkel L, Oldham F, Blaise D, Viens P. High-dose chemotherapy followed by reinfusion of selected CD34+ peripheral blood cells in patients with poor-prognosis breast cancer: a randomized multicentre study. Br J Cancer 1998 Oct;78(7):913-21. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9764583&dopt;=Abstract

Chabannon C, Novakovitch G, Blache JL, Olivero S, Camerlo J, Genre D, Maraninchi D, Viens P. The role of autologous hematopoietic progenitor and cell reinfusion for intensive chemotherapy in women with poor-prognosis breast cancer. Clinical studies with ex-vivo expanded cells produced with the Aastrom Replicell technology. Hematol Cell Ther 1999 Apr;41(2):78-81. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10344557&dopt;=Abstract

Chang Q, Hanks S, Akard L, Thompson J, Harvey K, English D, Jansen J. Maturation of mobilized peripheral blood progenitor cells: preclinical and phase I clinical studies. J Hematother 1995 Aug;4(4):289-97. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7489143&dopt;=Abstract

Chaouche M, Fizazi K, Zelek L, Cesne A L, Chevalier T L, Pechoux C L, Rochard F, Arriagada R, Laplanche A, Spielmann M. Phase II study of a dose-intensive combination of doxorubicin, cyclophosphamide, 5-fluoro-uracil, methotrexate and vincristine (avcmf) in patients with inflammatory breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A342.

Charrier S, Chollet P, Bay JO, Cure H, Kwiatkowski F, Portefaix G, Communal Y, Betail G, Plagne R, Chassagne J. Hematological recovery and peripheral blood progenitor cell mobilization after induction chemotherapy and GM-CSF plus G-CSF in breast cancer. Bone Marrow Transplant 2000 Apr;25(7):705-10. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10745254&dopt;=Abstract

Charrier S, Communal Y, Cure H, Chollet P, Portefaix G, Ferriere JP, Bignon YJ, Betail G, Plagne R, Chassagne J. Mobilization of peripheral blood stem cells (pbsc) after primary intense chemotherapy and granulocyte-colony stimulating factor (g-csf) in breast cancer [abstract]. Proc Annu Meet Am Assoc Cancer Res 1997;38:A168.

Cinieri S, Cocorocchio E, Ferrucci P, Martinoni A, Peccatori F, Civelli M, Cipolla C, Cardinale D, Agazzi A, Bertolini F, Martinelli G. No evidence of cardiotoxicity in high-dose chemotherapy regimen with docetaxel, epirubicin and ciclophosphamide regimen for poor prognosis breast cancer patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A215.

Cocorocchio E, Cinieri S, Ferrucci P, Peccatori F, Zimatore M, Taani Hani E, Agazzi A, Galimberti V, Luini A, Martinelli G. Non-cross resistant regimen using high-dose (hd) ifosfamide, carboplatin and etoposide (ice) in adjuvant setting for antracyclin resistant patients with high-risk breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A498.

Colozza M, Tabilio A, Gori S, Mosconi AM, Basurto C, Falzetti F, Bacchi M, Scarpelli N, Antonini G, Gerli P, Aristei C, Martelli MF, Tonato M. High-dose (hd) etoposide (vp16), thiotepa and carboplatin (cbdca) with peripheral blood stem cell (pbsc) rescue for high risk stage ii--iii and selected stage iv breast cancer (bc) patients (pts) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A509.

Copelan EA, Ceselski SK, Ezzone SA, Lasky LC, Penza SL, Bechtel TP, Klein JL, Hehmeyer DM, Scholl MD, Marshall DD, Elder PJ, Risley GL, Avalos BR. Mobilization of peripheral-blood progenitor cells with high-dose etoposide and granulocyte colony-stimulating factor in patients with breast cancer, non-Hodgkin's lymphoma, and Hodgkin's disease. J Clin Oncol 1997 Feb;15(2):759-65. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9053502&dopt;=Abstract

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deLima M, Mehra R, van Besien K, Giralt S, Rondon G, Mirza N, Gajewski J, Khouri I, Andersson B, Przepiorka D, Geisler D, Rodriguez E, Hortobagyi G, R Champlin. High-dose chemotherapy (hdct) and autologous blood and marrow transplant (bmt) for high-risk breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A383.

deMagalhaes-Silverman M, Rybka WB, Lembersky B, Bloom EJ, Lister J, Pincus SM, Voloshin M, Wilson J, Ball ED. High-dose cyclophosphamide, carboplatin, and etoposide with autologous stem cell rescue in patients with breast cancer. Am J Clin Oncol 1996 Apr;19(2):169-73. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8610643&dopt;=Abstract

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Elkordy M, Crump M, Vredenburgh JJ, Petros WP, Hussein A, Rubin P, Ross M, Gilbert C, Modlin C, Meisenberg B, Coniglio D, Rabinowitz J, Laughlin M, Kurtzberg J, Peters WP. A phase I trial of recombinant human interleukin-1 beta (OCT-43) following high-dose chemotherapy and autologous bone marrow transplantation. Bone Marrow Transplant 1997 Feb;19(4):315-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9051240&dopt;=Abstract

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Elling D, Krocker J, Kummel S, Heinrich J, Kohls A, Blohmer J, Breitbach P, Schlosser H, Lichtenegger W. Epirubicin/paclitaxel vs. Epirubicin /cyclophosphamide as first-line dose-intensive adjuvant chemotherapy in breast cancer patients with 4-9 /over 9 (second group) positive nodes: preliminary data of this phase II/III trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A349.

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Fay J, Jones S, Lynch J, Herzig R, Christiansen N, Pineiro L, Collins R Jr, Freeman B, Herzig G. The treatment of primary breast cancer with intensive thiotepa (tpa), cyclophosphamide (cpa) and hematopoietic stem cell (hsc) transplantation: a phase II trial of the north american marrow transplant group [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A117.

Fetting JH, Gray R, Fairclough DL, Smith TJ, Margolin KA, Citron ML, Grove-Conrad M, Cella D, Pandya K, Robert N, Henderson IC, Osborne CK, Abeloff MD. Sixteen-week multidrug regimen versus cyclophosphamide, doxorubicin, and fluorouracil as adjuvant therapy for node-positive, receptor-negative breast cancer: an Intergroup study. J Clin Oncol 1998 Jul;16(7):2382-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9667255&dopt;=Abstract

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Filip S, Blaha M, Odrazka K, Mericka P, Vavrova J. Application of whole blood and peripheral blood progenitor cells (PBPC) and new strategies for rescue after intensive cyclic chemotherapy in high-risk breast cancer. J Hematother Stem Cell Res 2000 Feb;9(1):31-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10738969&dopt;=Abstract

Findlay B, Tonkin K, Crump M, Norris B, Trudeau M, Blackstein M, Burnell M, Skillings J, Bowman D, Walde D, Levine M, Palmer M, Myles J, James K. A dose escalation trial of adjuvant cef chemotherapy with g-csf for premenopausal women with node-positive breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A60.

Findlay B, Tonkin K, Crump M, Norris B, Trudeau M, Blackstein M, Burnell M, Skillings J, Bowman D, Walde D, Levine M, Palmer M, Myles J, James K. A dose escalation trial of adjuvant cef chemotherapy with g-csf for premenopausal women with node-positive breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A60.

Fisher B, Anderson S, DeCillis A, Dimitrov N, Atkins JN, Fehrenbacher L, Henry PH, Romond EH, Lanier KS, Davila E, Kardinal CG, Laufman L, Pierce HI, Abramson N, Keller AM, Hamm JT, Wickerham DL, Begovic M, Tan-Chiu E, Tian W, Wolmark N. Further evaluation of intensified and increased total dose of cyclophosphamide for the treatment of primary breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-25. J Clin Oncol 1999 Nov;17(11):3374-88. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10550131&dopt;=Abstract

Fisher B, Anderson S, Wickerham DL, DeCillis A, Dimitrov N, Mamounas E, Wolmark N, Pugh R, Atkins JN, Meyers FJ, Abramson N, Wolter J, Bornstein RS, Levy L, Romond EH, Caggiano V, Grimaldi M, Jochimsen P, Deckers P. Increased intensification and total dose of cyclophosphamide in a doxorubicin-cyclophosphamide regimen for the treatment of primary breast cancer: Findings from National Surgical Adjuvant Breast and Bowel Project B- 22. J Clin Oncol 1997;15(5):1858-69. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9164196&dopt;=Abstract

Fountzilas G, Nicolaides C, Aravantinos G, Skarlos D, Kosmidis P, Papakostas P, Stathopoulos GP, Kontostolis E, Bafaloukos D, Pavlidis N. Dose-dense adjuvant chemotherapy with epirubicin monotherapy in patients with operable breast cancer and greater than and equal to 10 positive axillary lymph nodes: A feasibility study. Oncology (Basel) 1998;55(6):508-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9778614&dopt;=Abstract

Fox KR, Moore HC, Mick R, Sickles C, Mangan PA, Solin LJ, Glatstein E, Buzby GP, Luger SM, Porter DL, Schuchter LM, Loh E, Schuster S, Silberstein L, Stadtmauer EA. Impact of adjuvant stem cell transplantation on the delivery of local radiation therapy in high risk breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A221.

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Fukutomi T, Akashi S, Nanasawa T, Yamamoto H. Adjuvant six cycles of high-dose adriamycin, cyclophosphamide, methotrexate, 5-fluorouracil (ACMF) vs 12 cycles of low-dose ACMF with tamoxifen for premenopausal, node-positive breast cancer patients: Results of a prospective randomized study. J Surg Oncol 1995;60(4):242-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8551733&dopt;=Abstract

Fumoleau P, Bremond A, Kerbrat P, Fargeot P, Namer M, Montcuquet Ph, Mihura J, Goudier MJ, Monnier A, Bardonnet M, Chapelle-Marcillac I, Luporsi E. Better outcome of premenopausal node-positive (n+) breast cancer patients (pts) treated with 6 cycles vs 3 cycles of adjuvant chemotherapy: eight year follow-up results of fasg 01 [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A252.

Fumoleau P, Chauvin F, Namer M, Bugat R, Tubiana-Hulin M, Guastalla JP, Delozier T, Kerbrat P, Devaux Y, Bonneterre J, Filleul A. Three-year follow-up results of adjuvant chemotherapy with ac versus high-dose mitoxantrone, cyclophosphamide (mc) with filgrastim in operable breast cancer involving 10 or more axillary lymph nodes [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A504.

Fumoleau P, Gomez F, Namer M, Bugat R, Tubiana-Hulin M, Guastalla JP, Delozier T, Cals L, Lebourgeois JP, Martin C, Filleul A, Clavel M. Factors predicting for clinical outcome following adjuvant chemotherapy with AC versus high dose mitoxantrone, cyclophosphamide (MC) with filgrastim in operable breast cancer involving 10 or more axillary lymph nodes [abstract]. Breast Cancer Res Treat 1997;46(1):67.

Gale RP, Park RE, Dubois R, Bitran JD, Buzdar A, Hortobagyi G, Jones SE, Lazar GS, Spitzer G, Swain SM, Vaughn CB, Vogel CE, Martino S. Delphi-panel analysis of appropriateness of high-dose chemotherapy and blood cell or bone marrow autotransplants in women with breast cancer. Clin Transplant 2000;14(1):32-41. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10693633&dopt;=Abstract

Galligioni E, Cetto G, Nascimben O, Buonadonna A, Crivellari D, Molino A, Veronesi A, Graif C, Barni S, Puccetti C, Ferrazzi E, Recaldin E, Sacco C. Adjuvant chemotherapy with high-dose epirubicin and cyclophosphamide vs CMF in high risk premenopausal breast cancer patients (PTS): Prospective randomized phase III trial [abstract]. Breast Cancer Res Treat 1996;37 Suppl:78.

Gallioioni E, Cetto G, Nascimben O, Buonadonna A, Crivellari D, Molino A, Veronesi A, Graiff C, Barni S, Puccetti C, Ferrazzi E, Recaldin E, Sava C, Saracchini S, Sacco C. Adjuvant chemotherapy with high-dose epirubicin and cyclophosphamide versus cyclophosphamide (ec), methotrexate, fluorouracil (cmf) in high risk premenopausal breast cancer patients (pts). A prospective randomized trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A508.

Garcia Castro I, Hornedo J, Benavides M, Ruiz A, Hidalgo M, Trigo JM, Hitt R, Costas P, Borstein R, Montalban MA, Cortes-Funes H. High-dose cmt: carboplatin, escalating doses of mitoxantrone, and thiotepa with g-csf-mobilized pbsc support, in breast and ovarian cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A1032.

Garcia-Conde J, Sola C, Solano C, Azagra P, Hornedo J, Cortes-Funes H, Lopez JJ, Lluch A. High-dose chemotherapy (hdct) and autologous peripheral stem-cell transplantation (apsct) after standard chemotherapy (ct) in high-risk breast cancer patients (greater than or equal to 10 axillary node involvement after surgery) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A994.

Garcia-Conde J, Solano C, Benet I, Lluch A, Marugan I, Cervantes A, Azagra P, Arbona C, Gutierrez A. Recovery of cytotoxic/suppressor cells predicts tumor relapse after high-dose chemotherapy (hdc) and peripheral blood progenitor cells transplantation (pbpct) in high risk breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A356.

Garcia-Conde J, Solano C, Lluch A, Arbona C, Benet I, Marugan I, Vercher J, Tormo M, Cervantes A, Alberola V. High-dose (hd) chemotherapy (ct) and autologous stem-cell transplantation (asct) in breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A941.

Gianni AM, Piccart MJ. Optimising chemotherapy dose density and dose intensity. new strategies to improve outcomes in adjuvant therapy for breast cancer. Eur J Cancer 2000 Apr;36 Suppl 1:S1-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10785602&dopt;=Abstract

Gianni AM, Siena S, Bregni M, Di Nicola M, Orefice S, Cusumano F, Salvadori B, Luini A, Greco M, Zucali R, Rilke F, Zambetti M, Valagussa P, Bonadonna G. Efficacy, toxicity, and applicability of high-dose sequential chemotherapy as adjuvant treatment in operable breast cancer with 10 or more involved axillary nodes: five-year results. J Clin Oncol 1997 Jun;15(6):2312-21. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9196145&dopt;=Abstract

Goldberg SL, Pecora AL, Jennis AA, Preti RA. Anthracycline chemotherapy followed by outpatient autologous pbsc transplantation for >=10 node positive breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A225.

Gradishar WJ, Tallman MS, Abrams JS. High-dose chemotherapy for breast cancer. Ann Intern Med 1996 Oct 1;125(7):599-604. Comment in: Ann Intern Med 1997 Jun 1;126(11):917; discussion 918; Ann Intern Med 1997 Jun 1;126(11):917-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8815759&dopt;=Abstract

Graham M, Gonzalez P, Cance W, Calvo B, Halle J, Rosenman J, Steagall A, Liu E. Dose-intensive sequential adriamycin (a) and iv cmf (a----cmf) with g-csf (g) support for stage ii and iii breast cancer (brca): a feasible and effective outpatient regimen [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A137.

Greinix HT, Linkesch W, Seifert M, Kubista E, Czerwenka K, Elahi F, Zielinski C, Hoecker P, Steger G, Schulenburg A, Neumeister G, Rabitsch W, Jakesz R, Kalhs P. Paclitaxel-containing high-dose chemotherapy in high-risk breast cancer patients. Acta Oncol 2000;39(1):47-52. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10752653&dopt;=Abstract

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Haas R, Schmid H, Hahn U, Hohaus S, Goldschmidt H, Murea S, Kaufmann M, Wannenmacher M, Wallwiener D, Bastert G, Hunstein W. Tandem high-dose therapy with ifosfamide, epirubicin, carboplatin and peripheral blood stem cell support is an effective adjuvant treatment for high-risk primary breast cancer. Eur J Cancer 1997 Mar;33(3):372-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9155519&dopt;=Abstract

Haas R, Schmid H, Hahn U, Hohaus S, Murea S, Wallwiener D, Goldschmidt H, Kaufmann M, Wannenmacher M, Bastert G, Hunstein W. Tandem high-dose therapy with peripheral blood stem cell (PBSC) support is an effective adjuvant treatment for high-risk primary breast cancer [abstract]. Ann Hematol 1996;73 Suppl 2:A2.

Hansen KS, Hansen LK, Lanier KS. High-dose chemotherapy (hdc) with cytoxan, thiotepa and carboplatin (stamp v) and autologous hematopoietic stem cell transplantation (ahst) in stage ii, iii, and iv breast cancer: a community program experience [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A365.

Havlin K. A phase I/phase II trial of granulocyte colony-stimulating factor as bone marrow support in patients treated with vinorelbine (Navelbine): study design and goals. Semin Oncol 1995 Apr;22(2 Suppl 5):38-40; discussion 41-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7537912&dopt;=Abstract

Hietanen P, Teerenhovi L, Joensuu H. Intensified adjuvant cyclophosphamide, methotrexate and 5-fluorouracil therapy: a dose-finding study for ambulatory patients with breast cancer. Oncology 1999;56(2):103-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9949294&dopt;=Abstract

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Hohaus S, Martin S, Schneeweiss A, Voso MT, Schlenk RF, Wallwiener D, Bastert G, Haas R. Adjuvant high-dose therapy with peripheral blood stem cell support for patients with high-risk breast cancer. Cancer Chemother Pharmacol 1999;44 Suppl:S13-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10602904&dopt;=Abstract

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Hohaus S, Wallwiener D, Schneeweiss A, Egerer G, Martin S, Abdallah A, Goldschmidt H, Fersis N, Bastert G, Haas R. Sequential high-dose chemotherapy with peripheral blood stem cell (PBSC) support as adjuvant therapy for patients with high-risk breast cancer. Bone Marrow Transpl 1998;22 Suppl 3:S93-4.

Holland HK, Dix SP, Geller RB, Devine SM, Heffner LT, Connaghan DG, Hillyer CD, Hughes LL, Miller RL, Moore MR, Winton EF, Wingard JR. Minimal toxicity and mortality in high-risk breast cancer patients receiving high-dose cyclophosphamide, thiotepa, and carboplatin plus autologous marrow/stem-cell transplantation and comprehensive supportive care. J Clin Oncol 1996 Apr;14(4):1156-64. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8648370&dopt;=Abstract

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Hortobagyi GN, Buzdar AU, Theriault RL, Valero V, Frye D, Booser DJ, Holmes FA, Giralt S, Khouri I, Andersson B, Gajewski JL, Rondon G, Smith TL, Singletary SE, Ames FC, Sneige N, Strom EA, McNeese MD, Deisseroth AB, Champlin RE. Randomized trial of high-dose chemotherapy and blood cell autografts for high-risk primary breast carcinoma. J Natl Cancer Inst 2000 Feb 2;92(3):225-33. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10655439&dopt;=Abstract

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Hudis C, Fornier M, Riccio L, Lebwohl D, Crown J, Gilewski T, Surbone A, Currie V, Seidman A, Reichman B, Moynahan M, Raptis G, Sklarin N, Theodoulou M, Weiselberg L, Salvaggio R, Panageas KS, Yao TJ, Norton L. Five-year results of dose-intensive sequential adjuvant chemotherapy for women with high-risk node-positive breast cancer: A phase II study. J Clin Oncol 1999;17(4):1118-26. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10561169&dopt;=Abstract

Hudis C, Seidman A, Baselga J, Raptis G, Lebwohl D, Gilewski T, Moynahan M, Sklarin N, Fennelly D, Crown JP, Surbone A, Uhlenhopp M, Riedel E, Yao TJ, Norton L. Sequential dose-dense doxorubicin, paclitaxel, and cyclophosphamide for resectable high-risk breast cancer: feasibility and efficacy. J Clin Oncol 1999 Jan;17(1):93-100. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10458222&dopt;=Abstract

Hudis C, Seidman A, Raptis G, Baselga J, Fennelly D, Theodoulou M, Gilewski T, Currie V, Moynahan M, Surbone A, Sklarin N, Robles M, Riccio L, Yao T, Uhlenhopp M, Norton L. Sequential (seq) dose-dense (dd) doxorubicin (a)/paclitaxel (t)/cyclophosphamide (c) is less toxic than a/concurrent (con) t+c as adjuvant therapy in resected node positive (+) breast cancer (npbc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A143.

Hudis C, Seidman A, Raptis G, Fennelly D, Gilewski T, Baselga J, Theodoulou M, Sklarin N, Moynahan M, Surbone A, Currie V, Lebwohl D, Uhlenhopp M, Crown J, Norton L. Sequential adjuvant therapy: The Memorial Sloan-Kettering Cancer Center experience. Semin Oncol 1996;23(1 Suppl 1):58-64. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8629040&dopt;=Abstract

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Hurd DD, Peters WP. Randomized, comparative study of high-dose (with autologous bone marrow support) versus low-dose cyclophosphamide, cisplatin, and carmustine as consolidation to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for patients with operable stage II or III breast cancer involving 10 or more axillary lymph nodes (CALGB Protocol 9082). Cancer and Leukemia Group B. J Natl Cancer Inst Monogr 1995;(19):41-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7577204&dopt;=Abstract

Hussein A, Plumer M, Vredenburgh J, Smith N, Fishman B, Matters L, Affronti ML, Coniglio D, Elkordy M, Rubin P, Ross M, Gilbert C, Petros WP, Peters WP. High-dose chemotherapy (hdc) with cyclophosphamide (c) cisplatin (p), and bcnu (b) (cpb) and autologous bone marrow (abm) and peripheral blood progenitor cells (pbpcs) for stage ii/iii breast cancer involving 4-9 axillary lymph nodes [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A1026.

Illarramendi JJ, Molina F, Tejedor M, Dominguez MA, Arias F, Martinez E, Duenas MT, Valerdi JJ. Combined approach with a short dose-intensity regimen plus sequential irradiation and tamoxifen for breast cancer patients with greater than or equal to 10 involved axillary nodes [abstract]. Paper presented at: 6th International Congress on Anti-Cancer Treatment; 1996 Feb 6-9; Paris.

Insa A, Prosper F, Lluch A, Garcia T, Martinez-Duenas E, Arbona C, Solano C, Benet I, Martinez-Agullo A, Garcia-Conde J. A case control study of high dose chemotherapy (hdc) with stem cell transplant (sct) in inflammatory breast cancer (ibc) and high risk breast cancer (hrbc) after primary chemotherapy (pc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A320.

Isaacs R, Adkins D, Spitzer G, Freeman S, Pecora A, Weaver C. A phase III multi-institution randomized study comparing standard adjuvant chemotherapy to intensification with high-dose chemotherapy (hdc) and autologous peripheral blood progenitor cell (pbpc) rescue in patients with stage ii/iiia breast cancer with 4-9 involved axillary lymph nodes [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A361.

Ito Y, Takahashi S, Aiba K, Osawa H, Mizunuma N, Uno S, Hanai M, Yamada Y, Horikoshi N. Modified high-dose ctcb regimen with intensified carboplatin is feasible and promising in patients with breast cancer in high-risk adjuvant setting [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A566.

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Johansen MJ, Madden T, Mehra RC, Wood JG, Rondon G, Browne V, Newman RA, Champlin RE. Phase I pharmacokinetic study of multicycle high-dose carboplatin followed by peripheral-blood stem-cell infusion in patients with cancer. J Clin Oncol 1997 Apr;15(4):1481-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9193344&dopt;=Abstract

Kaeslingk B, Perry J, Cruz J, Neijstrom E, Hopkins J, Hurd D. Multi-modality therapy including high dose cyclophosphamide, thiotepa, and carboplatin (ctcb) with autologous stem cell transplantation (asct) for poor prognosis stage ii-iii breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A961.

Krueger WH, Kroeger N, Stockschlaeder M, Hoffknecht MM, Krzizanowski C, Hossfeld DK, Jonat W, Zander AR. Adjuvant high-dose cyclophosphamide/thiotepa/mitoxantrone with peripheral blood stem cell support in women with high-risk breast cancer [abstract]. Onkologie 1995;18 Suppl 2:102.

Lalisang RI, Hupperets PS, ten Haaft MA, Jansen RL, Schouten HC. High-dose chemotherapy with autologous bone marrow support as consolidation after standard-dose adjuvant therapy in primary breast cancer patients with seven or more involved axillary lymph nodes. Bone Marrow Transplant 1998 Feb;21(3):243-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9489646&dopt;=Abstract

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Leonard RC. The advancement of high-dose chemotherapy and dose intensification schedules. Ann Oncol 1997;8 Suppl 3:S3-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9341958&dopt;=Abstract

Leonard RC. High-dose chemotherapy for breast cancer. Eur J Cancer 1996 Feb;32A(2):205-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8664028&dopt;=Abstract

Leonard RC. High dose chemotherapy for breast cancer: the case for trials in adjuvant therapy. J R Soc Med 1996 Jun;89(6):337P-9P. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8758193&dopt;=Abstract

Leonard RC. The importance of dose and schedule in cancer chemotherapy: breast cancer. Anticancer Drugs 1995 Oct;6 Suppl 5:17-27. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8845492&dopt;=Abstract

Levine MN, Bramwell VH, Pritchard KI, Norris BD, Shepherd LE, Abu-Zahra H, Findlay B, Warr D, Bowman D, Myles J, Arnold A, Vandenberg T, MacKenzie R, Robert J, Ottaway J, Burnell M, Williams CK, Tu D. Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 1998 Aug;16(8):2651-8. Comment in: J Clin Oncol 1998 Dec;16(12):3916-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9704715&dopt;=Abstract

Lindman H, Wiklund T, Holte H, Ljungman P, Blomqvist C, Kvalheim G, Bengtsson M, Hoglund M, Wilking N, Bergh J. FEC mobilized stem cells for high-dose therapy in breast cancer patients. SB6 9401 Study Group. Acta Oncol 1999;38(2):239-45. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10227447&dopt;=Abstract

Lluch A, Azagra P, Solano C, Marugan I, Paz L D, Benet I, Cervantes A, Arbona C, Garcia-Conde J. A case-control study of adjuvant high dose chemotherapy (hdct) and peripheral blood stem cell (pbsc) transplantation or conventional chemotherapy (ct) in operable breast cancer (bc) patients (pts) with 10 or more involved nodes [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A592.

Lluch A, Sola C, Hornedo J, Germa JR, Benavides M, Baselga J, Guillen V, Cruz JJ, Alvarez I, Mayordomo JI, Prosper F, Ojeda B, Alonso S, Cortes H, Lopez JJ, Garcia-Conde J. High dose chemotherapy (hdc) and stem cell transplant (sct) for high risk breast cancer (hrbc): results of 235 transplants [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A303.

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Malik S, Tabbara IA. High-dose chemotherapy (hdc) with autologous hematopoietic stem cell transplantation (ahsct) for stage ii/iii and stage iv breast cancer three-year follow-up [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A201.

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Marti JL, Velilla MC, Mayordomo JI, Cajal R, Yubero A, Bueso P, Herraez J, Murillo L, Lopez P, Valencia J, Esco R, Isla MD, Saenz A, Escudero P, Garcia MD, Tres A. Safety of extensive locorregional radiotherapy (rt) after hematological engraftment post high-dose chemotherapy (hdch) with peripheral-blood stem cell (pbsc) rescue in high-risk breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A370.

Martin M. High-dose chemotherapy for breast cancer: clinical advantages of autologous peripheral blood progenitor cells (PBPC) compared with autologous bone marrow transplantation (ABMT). Ann Oncol 1995;6 Suppl 4:33-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8750143&dopt;=Abstract

Martinelli G, Cocorocchio E, Ferrucci PF, Peccatori F, Cinieri S, Motta M, Veronesi P, Agazzi A, Goldhirsch A. Multiple high dose (hd) chemotherapy with peripheral blood progenitor cells (pbpc) reinfusion in high risk breast cancer patients (pts) after antracycline-containing primary chemotherapy. Preliminary results [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A605.

Massidda B, Ionta MT, Casula P, Broccia G. Late intensification therapy with or without pbpc support in operable breast cancer larger than 3 cm and more than 10 positive nodes [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A433.

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McCarthy PL, Hurd DD, Rowlings PA, Crump M, Gale RP, Lazarus HM , Vaughan WP, Weinberger BB, Wiemann MC, Freytes CO, Cirenza E, Antman KH. Autotransplants in men with breast cancer. Bone Marrow Transplant 1999;24(4):365-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10467324&dopt;=Abstract

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Mikhak B, Zahurak M, Abeloff MD, Fetting JH, Davidson NE, Donehower RC, Waterfield W, Kennedy MJ. Long term follow-up of women treated with 16-week, dose-intensive adjuvant chemotherapy for high risk breast carcinoma. Cancer 1999 Feb 15;85(4):899-904. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10091768&dopt;=Abstract

Morrell L, Fernandez HF, Krill E, Goodman M, Spector N, Hanlon J, Cassileth PA. High dose chemotherapy (hdc) and peripheral blood stem cell (pbsc) transplantation in inflammatory breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A953.

Mulder NH, van der Mark TW, Dolsma WV, van der Graaf WT, Willemse PH, Sleijfer DT, de Vries EG. Serial pulmonary diffusion capacity analyses in randomized adjuvant breast cancer study +/- high-dose chemotherapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A644.

Murphy K, Coombes RC, Samson D, Craddock C, Olavarria E, Yong A, Rajan S, Wagner S, Stern S, Kanfer EJ. Effective mobilisation of peripheral blood stem cells in patients with high-risk primary breast cancer following adjuvant chemotherapy (FEC) and G-CSF [abstract]. Br J Haematol 1998;101 Suppl 1:92.

Namer M, Chauvin F, Fumoleau P, Bugat R, Tubiana-Hulin M, Guastala JP, Delozier T, Kerbrat P, Devaux Y, Bonneterre J, Filleul A. Adriamycin-cyclophosphamide versus high-dose mitoxantrone-cyclophosphamide plus filgrastim in operable node-positive (>=10) breast cancer: five-year follow-up [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A294.

Narabayashi M, Takeyama K, Fukutomi T, Tokuda Y, Tajima T, Okumura A, Chou T, Sano M, Makino H, Igarashi T, Sasaki Y, Imoto S, Ogura M, Morishima Y, Murai H, Okamoto S, Ikeda T, Kasai M, Yokozawa T, Tobinai K. A dose-finding study of lenograstim (glycosylated rHuG-CSF) for peripheral blood stem cell mobilization during postoperative adjuvant chemotherapy in patients with breast cancer. Lenograstim/Breast Cancer Study Group. Jpn J Clin Oncol 1999 Jun;29(6):285-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10418556&dopt;=Abstract

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Nieto Y, Cagnoni PJ, Bearman SI, Shpall EJ, Ross M, Jones RB. High-dose chemotherapy (hdc) with cisplatin (cddp), cyclophosphamide (cpa) and bcnu (ccb), followed by autologous hematopoietic progenitor cell support (ahpcs) for inflammatory breast cancer (ibc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A436.

Nieto Y, Nawaz S, Cagnoni PJ, Shpall EJ, Bearman SI, Jones RB. Overexpression of her2/neu (h2n), but not p53 mutations, is a poor prognostic factor in high-risk primary breast cancer (hrpbc) treated with high-dose chemotherapy (hdc) and autologous stem-cell transplant (asct) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A290.

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Palangie T, Bourgeois H, Texier V, Beuzeboc P, Dieras V, Dorval T, Garcia-Giralt E, Jouve M, Kalla S, Scholl S, Viens P, Pouillart P. High pathological response rate in inflammatory breast cancer (ibc) with multiple cycle high dose chemotherapy and peripheral blood progenitor cell (pbpc) support [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A974.

Palangie T, Dorval T, Beuzeboc P, Sellami F, Dieras V, Jouve M, Pierga JY, Scholl S, Pouillart P. Multiple cycle high dose doxorubicine (d), cyclophosphamide (c) and taxotere@ (txt) with peripheral blood progenitor cells (pbpc) and rhg-csf, for inflammatory breast cancer (ibc): a feasibility study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A630.

Perez L, Kopel S, Fan Y, Carinci D, Razia S, Banad A, Nayak A, Grand M, Malhotra H, Celo J, Cheslock E, Fitzgerald D, Feldman A, Daya R, Grinberg M, Abraham N, Chachoua A, Cook P. Feasibility of a novel regimen of high-dose thiotepa (t), l-phenylalanine (l), and carboplatin (c) with autologous hematopoietic stem cell transplantation (auhsct) in breast cancer (bc) patients (pts) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A1001.

Peters WP, Dansey R, Klein J, Berry D. High-dose chemotherapy for high-risk primary breast cancer. Proc Int Conf Adjuv Ther Cancer 1997;8:117-22.

Peters WP, Dansey RD, Klein JL, Baynes RD. High-dose chemotherapy and peripheral blood progenitor cell transplantation in the treatment of breast cancer. Oncologist 2000;5(1):1-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10706643&dopt;=Abstract

Petruska PJ, Visconti JL, Walsh WK, Dunphy FR, Pincus SM, Broun ER, McIntyre W. Phase I/II trial of the addition of escalating doses of paclitaxel to high dose (hd) carboplatin/cyclophosphamide with peripheral blood stem cell (pbsc) support in high risk breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A637.

Pharmacokinetics of thiotepa and mitoxantrone in adjuvant high-dose chemotherapy with autologous stem cell support of patients with high risk breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A901.

Piccart MJ, Biganzoli L, Di Leo A. The impact of chemotherapy dose density and dose intensity on breast cancer outcome: what have we learned? Eur J Cancer 2000 Apr;36 Suppl 1:S4-10. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10785603&dopt;=Abstract

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Raab G, Minckwitz G, Costa S, Hilfrich J, Blohmer J, Merkle E, Eidtmann H, Jackich C, Tulusan AH, Gademann G, Graf E, Kaufmann M. Gepardo (german preoperative adriamycin docetaxel) trial comparing a combination of dose-intensified adriamycin and docetaxel with or without tamoxifen as preoperative therapy in patients with operable breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A377.

A randomized single-institution study of high-dose chemotherapy with cyclophosphamide, thiotepa and carboplatin (ctc) in high-risk breast cancer [abstract]. Proc Annu Meet Am Assoc Cancer Res 1997;38:A2927.

Raschko J, Somlo G, Doroshow JH, Forman S, Molina A, Veer A Te, Longmate J, Chow W, Leong L, Morgan R, Margolin K, McNamara M, Shibata S, Tetef M, Yen Y. High-dose chemotherapy and stem-cell rescue (hdct) in the treatment of high-risk breast cancer (hrbc): update of relapse-free (rfs) and overall survival (os) at 5 years [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A316.

Reed E, Tarantolo S, Edwards B, Silverberg D, Block M, Langdon R, Kessinger A. Treatment of high-risk breast cancer patients (pts) with cyclophosphamide (c), etoposide (v), cisplatin (p) and peripheral blood stem cells (pbsc) in an outpatient (opt) setting [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A1015.

Restrepo A, Fernandez HF, Morrell L, Spector N, Goodman M, Smith RJ, Hanlon J, Cassileth PA. Safety of high-dose chemotherapy and autologous peripheral blood stem cell transplantation (pbsct) for breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A1020.

Ribas A, Albanell J, Bellmunt J, Sole-Calvo LA, Bermejo B, Gallardo E, Vidal R, Vera R, Eres N, Carulla J, Baselga J. Five-day course of granulocyte colony-stimulating factor in patients with prolonged neutropenia after adjuvant chemotherapy for breast cancer is a safe and cost-effective schedule to maintain dose-intensity. J Clin Oncol 1996 May;14(5):1573-80. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8622074&dopt;=Abstract

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Rushing DA. High-dose chemotherapy for breast cancer [letter]. Ann Intern Med 1997 Jun 1;126(11):917; discussion 918. Comment on: Ann Intern Med 1996 Oct 1;125(7):599-604. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9163301&dopt;=Abstract

Saarto T, Blomqvist C, Rissanen P, Auvinen A, Elomaa I. Haematological toxicity: a marker of adjuvant chemotherapy efficacy in stage II and III breast cancer. Br J Cancer 1997;75(2):301-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9010042&dopt;=Abstract

Scandinavian Breast Cancer Study Group. Results from a randomized adjuvant breast cancer study with high dose chemotherapy with ctc[subscript b] supported by autologous bone marrow stem cells versus dose escalated and tailored fec therapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A3.

Schiffman KS, Bensinger WI, Appelbaum FR, Rowley S, Lilleby K, Clift RA, Weaver CH, Demirer T, Sanders JE, Petersdorf S, Gooley T, Weiden P, Zuckerman N, Montgomery P, Maziarz R, Klarnet J P, Rivkin S, Trueblood K, Storb R, Holmberg L, Buckner CD. Phase II study of high-dose busulfan, melphalan and thiotepa with autologous peripheral blood stem cell support in patients with malignant disease. Bone Marrow Transplant 1996;17(6):943-50. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8807098&dopt;=Abstract

Schmoor C, Schumacher M. Methodological arguments for the necessity of randomized trials in high-dose chemotherapy for breast cancer. Breast Cancer Res Treat 1999 Mar;54(1):31-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10369078&dopt;=Abstract

Schouten H, Lalisang R, Hupperets P, ten Haaft M, Jansen R. High-dose chemotherapy (hdc) with autologous bone marrow support (abms) in primary breast cancer patients with seven or more involved axillary lymph nodes [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A442.

Schwartzberg L, Weaver C, Lewkow L, McAneny B, Zhen B, Birch R, West W, Tauer K, Buckner C. High-dose chemotherapy with peripheral blood stem cell support for stage IIIB inflammatory carcinoma of the breast. Bone Marrow Transplant 1999 Nov;24(9):981-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10556957&dopt;=Abstract

Schwartzberg LS, Birch R, Tauer KW, Leff R, Greco FA, Hainsworth J, Raefsky E, McAneny B, Weaver Z, West J, Buckner CD, Weaver CH. Adjuvant dose-intense chemotherapy with peripheral blood stem cell support in stage II-III breast cancer with five to nine involved axillary lymph nodes. Am J Clin Oncol 1999 Apr;22(2):136-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10199446&dopt;=Abstract

Schwartzberg LS, Birch R, West WH, Tauer KW, Wittlin F, Leff R, Campos L, Rymer W, Carter P, Mangum M, Greco FA, Hainsworth J, Raefsky E, Blanco R, Buckner CD, Weaver CH. Sequential treatment including high-dose chemotherapy with peripheral blood stem cell support in patients with high-risk stage II-III breast cancer: outpatient administration in community cancer centers. Am J Clin Oncol 1998 Oct;21(5):523-31. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9781614&dopt;=Abstract

Scott S, Carter W, Link B, Fridman M, Lee M, Chrischilles E. Dose modifications in adjuvant therapy for early stage breast cancer: preliminary results from a multi-site study and a practice survey [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A381.

Setti M, Bignardi D, Ballestrero A, Ferrando F, Musselli C, Blanchi S, Basso M, Bosco O, Balleari E, Patrone F, Indiveri F. The induction of distinct cytokine cascades correlates with different effects of granulocyte-colony stimulating factor and granulocyte/macrophage-colony-stimulating factor on the lymphocyte compartment in the course of high-dose chemotherapy for breast cancer. Cancer Immunol Immunother 1999 Sep;48(6):287-96. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10473803&dopt;=Abstract

Shepherd L, Findlay B, Tonkin K, Crump M, Norris B, Trudeau M, Blackstein M, Burnell M, Skillings J, Bowman D, Walde D, Levine M, Palmer M, Myles J, James K. A dose escalation trial of adjuvant CEF chemotherapy with G-CSF for premenopausal women with node-positive breast cancer [abstract]. Clin Invest Med 1996;19(4 Suppl):S60.

Singh B, Elfenbein GJ, Kronish LE, Perkins JB, Fields KK. Survival duration after relapse following high-dose therapy and autologous hematopoietic stem cell transplantation for high risk breast cancer patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A411.

Singh RK, Varney ML, Buyukberber S, Ino K, Ageitos AG, Reed E, Tarantolo S, Talmadge JE. Fas-FasL-mediated CD4+ T-cell apoptosis following stem cell transplantation. Cancer Res 1999 Jul 1;59(13):3107-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10397252&dopt;=Abstract

Smith GA, Henderson IC. High-dose chemotherapy (HDC) with autologous bone marrow transplantation (ABMT) for the treatment of breast cancer: the jury is still out. Important Adv Oncol 1995:201-14. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7672807&dopt;=Abstract

Smith S, Grinblatt D, Huffman-Dertz S, Williams SF. Autologous peripheral blood stem cell rescue following high dose chemotherapy in inflammatory breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A331a.

Sobrevilla-Calvo P, Lara-Medina F, Martinez-Magana J, Calderon E, Acosta A, Zambrano C, Texcocano J, Museb P, Labardini J, Zinser JW. High dose (hd) gemcitabine (g)-paclitaxel (p)-cisplatin (c), with autologous peripheral blood stem cell transplantation (apbsct). A feasibility study of a novel conditioning regimen (cor) for breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A668.

Somlo G, Doroshow JH, Synold T, Reardon D, Chow W, Leong L, Morgan R J, Margolin K, Raschko J, Shibata S, Tetef M, Yen Y, Veer A te, Forman SJ. High-dose paclitaxel (t) in combination with adriamycin (a) and cyclophosphamide (c) with peripheral blood progenitor cell rescue (pbpc) in patients with breast cancer (bc); moderate toxicities and non-linear taxol pharmacokinetics [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A671.

Stewart DA, Nabholtz J-, Geggie P, Ruether JD, Craighead P, Gluck S, Smylie M, Mackey J, Paterson AH. Adjuvant and neoadjuvant use of high dose mitoxantrone, vinblastine, cyclophosphamide (mvc) and autologous stem cell support (ascs) for patients with poor prognosis stage ii/iii breast cancer (brca) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A389.

van der Wall E, Beijnen JH, Rodenhuis S. High-dose chemotherapy regimens for solid tumors. Cancer Treat Rev 1995 Mar;21(2):105-32. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7758003&dopt;=Abstract

van der Wall E, Nooijen WJ, Baars JW, Holtkamp MJ, Schorangel JH, Richel DJ, Rutgers EJ, Slaper-Cortenbach IC, van der Schoot CE, Rodenhuis S. High-dose carboplatin, thiotepa and cyclophosphamide (CTC) with peripheral blood stem cell support in the adjuvant therapy of high-risk breast cancer: a practical approach. Br J Cancer 1995 Apr;71(4):857-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7536025&dopt;=Abstract

van der Wall E, Rutgers EJ, Holtkamp MJ, Baars JW, Schornagel JH, Peterse JL, Beijnen JH, Rodenhuis S. Efficacy of up-front 5-fluorouracil-epidoxorubicin-cyclophosphamide (FEC) chemotherapy with an increased dose of epidoxorubicin in high-risk breast cancer patients. Br J Cancer 1996 May;73(9):1080-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8624267&dopt;=Abstract

Van Warmerdam LJ, Rodenhuis S, Van Der Wall E, Maes RA, Beijnen JH. Pharmacokinetics and pharmacodynamics of carboplatin administered in a high-dose combination regimen with thiotepa, cyclophosphamide and peripheral stem cell support. Br J Cancer 1996;73(8):979-84. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8611435&dopt;=Abstract

Viens P, Genre D, Gravis G, Cappiello MA, Camerlo J, Cowen D, Bertucci F, Houvenaeghel G, Penault-Llorca F, Chabannon C, Maraninchi D. High-dose-intensity doxorubicin-cyclophosphamide with rh-GCSF and peripheral blood stem cells: outpatient adjuvant treatment for premenopausal patients with breast carcinoma. Adjuv Ther Cancer 1997;8:123-9.

Viens P, Penault-Llorca F, Jacquemier J, Gravis G, Cowen D, Bertucci F, Houvenaeghel G, Blaise D, Maraninchi D. High-dose chemotherapy and haematopoietic stem cell transplantation for inflammatory breast cancer: pathologic response and outcome. Bone Marrow Transplant 1998 Feb;21(3):249-54. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9489647&dopt;=Abstract

Vij R, Adkins D, Brown R, Goodnough LT, Khoury H, Biondo M, Freytes C, Bachier C, DiPersio J. High-dose chemotherapy (hdct) and autologous stem cell transplant (asct) for locoregional recurrence of breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A692.

Vollmer RT. Re: Dose and dose intensity as determinants of outcome in the adjuvant treatment of breast cancer [letter]. J Natl Cancer Inst 1999 Feb 3;91(3):286-7. Comment on: J Natl Cancer Inst 1998 Aug 19;90(16):1205-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10037109&dopt;=Abstract

Weaver CH, Birch R, Schwartzberg LS, West WH. High-dose chemotherapy and autologous stem cell transplantation for breast cancer. Cancer Treat Res 1995;76:59-85. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7577345&dopt;=Abstract

Weiss RB. The randomized trials of dose-intensive therapy for breast cancer: what do they mean for patient care and where do we go from here? Oncologist 1999;4(6):450-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10631689&dopt;=Abstract

Wolmark N, Fisher B, Anderson S. The effect of increasing dose intensity and cumulative dose of adjuvant cyclophosphamide in node positive breast cancer: results of NSABP B-25 [abstract]. Breast Cancer Res Treat 1997;46(1):26.

Wormann B, Meden H, Riggert J, Humpe A, Wulf G, Koch B, Kohler M, Kuhn W, Hiddemann W. Early intensive and myeloablative adjuvant chemotherapy in women with high-risk breast cancer. Anticancer Res 1998 May-Jun;18(3C):2237-41. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9703793&dopt;=Abstract

Wright-Browne V, Hortobagyi GN. High-dose chemotherapy for breast cancer: twenty years later. Whom should we treat? And when? Tumori 1996 May-Jun;82(3):187-92. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8693591&dopt;=Abstract

Zambelli A, Da Prada GA, Pedrazzoli P, Ponchio L, Robustelli della Cuna G. Poor outcome of patients with resectable breast cancer receiving adjuvant high-dose sequential chemotherapy following preoperative treatment. Anticancer Res 1999 May-Jun;19(3B):2373-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10472359&dopt;=Abstract

Zander AR, Kruger W, Kroger N, Damon L, Konigmann M, Berdel WE, Gieseking F, Schafer-Eckart K, Mobus V, Frickhofen N, Wandt H, Illiger HJ, Metzner B, Kolbe K, Wormann B, Trumper L, Huber C, Hossfeld DK, Maass H, Jonat W. High dose mitoxantrone with thiotepa, cyclophosphamide and autologous stem cell rescue for high risk stage II and stage III breast cancer. German GABG-4/EH-93-Study. Bone Marrow Transplant 1996 Sep;18 Suppl 1:S24-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8899165&dopt;=Abstract

Zujewski J, Danforth D, Noone M, Kohler D, Venzon D, Cowan KH. Short course, dose intensive, 14 day cycles of doxorubicin (a) and cyclophosphamide (c) followed by infusional paclitaxel (t) in the treatment of high risk primary breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A145.

Zujewski J, Nelson A, Abrams J. Much ado about not...enough data: high-dose chemotherapy with autologous stem cell rescue for breast cancer. J Natl Cancer Inst 1998 Feb 4;90(3):200-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9462677&dopt;=Abstract

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## 5. Post-Mastectomy Adjuvant Radiotherapy

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Adjuvant therapy of breast cancer. Semin Radiat Oncol 1999 Jul;9(3):215-304. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378958&dopt;=Abstract

Alvarez A, Mickiewicz E, Caceres Y, Agusto S, Piris N, Brosio C, Giglio R, Cinat G, Ezcurdia L, Cresta C, et al. Retrospective analysis evaluating the need of postmastectomy radiotherapy (rt) in a group of stage iii breast cancer (bc) patients (pts) treated with a multidisciplinary approach [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A203.

Arriagada R, Rutqvist LE, Le MG. Postmastectomy radiotherapy: randomized trials. Semin Radiat Oncol 1999 Jul;9(3):275-86. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378967&dopt;=Abstract

Arriagada R, Rutqvist LE, Mattsson A, Kramar A, Rotstein S. Adequate locoregional treatment for early breast cancer may prevent secondary dissemination. J Clin Oncol 1995 Dec;13(12):2869-78. Comment in: J Clin Oncol 1995 Dec;13(12):2861-4; J Clin Oncol 1996 Apr;14(4):1403-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8523049&dopt;=Abstract

Ballo MT, Strom EA, Prost H, Singletary SE, Theriault RL, Buchholz TA, McNeese MD. Local-regional control of recurrent breast carcinoma after mastectomy: does hyperfractionated accelerated radiotherapy improve local control? Int J Radiat Oncol Biol Phys 1999 Apr 1;44(1):105-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10219802&dopt;=Abstract

Barrow BJ, Janjan NA, Gutman H, Benjamin RS, Allen P, Romsdahl MM, Ross MI, Pollock RE. Role of radiotherapy in sarcoma of the breast--a retrospective review of the M.D. Anderson experience. Radiother Oncol 1999 Aug;52(2):173-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10577703&dopt;=Abstract

Benediktsson K, Perbeck L. The influence of radiotherapy on skin circulation of the breast after subcutaneous mastectomy and immediate reconstruction. Br J Plast Surg 1999 Jul;52(5):360-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10618978&dopt;=Abstract

Bijker N, Rutgers EJ, Peterse JL, van Dongen JA, Hart AA, Borger JH, Kroon BB. Low risk of locoregional recurrence of primary breast carcinoma after treatment with a modification of the Halsted radical mastectomy and selective use of radiotherapy. Cancer 1999 Apr 15;85(8):1773-81. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10223572&dopt;=Abstract

Boyages J, Langlands A. Postmastectomy radiation therapy: better late than never. Aust N Z J Surg 1998 Aug;68(8):550-3. Comment in: Aust N Z J Surg 1998 Aug;68(8):549. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9715129&dopt;=Abstract

Brenin DR, Morrow M, Moughan J, Owen J, Wilson JF, Winchester DP. Current management of axillary lymph nodes in breast cancer: a national patterns of care study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A380.

Buzdar AU, Mcneese MD, Hortobagyi GN, Smith TL, Kau S, Fraschini G, Hug V, Ellerbroek N, Holmes FA, et al. Is chemotherapy effective in reducing the local failure rate in patients with operable breast cancer? Cancer 1990;65(3):394-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=2297630&dopt;=Abstract

Cazzaniga LF, Bossi A, Cosentino D, Frigerio M, Martinelli A, Monti A, Morresi A, Ostinelli A, Scandolaro L, Valli MC, Besana G. Radiological findings when very small lung volumes are irradiated in breast and chest wall treatment. Radiat Oncol Invest 1998;6(1):58-62.

Chaney AW, Pollack A, McNeese MD, Zagars GK. Adjuvant radiotherapy for phyllodes tumor of breast. Radiat Oncol Investig 1998;6(6):264-7. Comment in: Radiat Oncol Investig 1998 ;6(6):289-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9885942&dopt;=Abstract

Chaudary MA, Tong D, Millis R, Smith P, Fentiman IS, Rubens RD. Loco-regional recurrence following mastectomy for early breast carcinoma: efficacy of radiotherapy at the time of recurrence. Eur J Surg Oncol 1997 Aug;23(4):348-53. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9315067&dopt;=Abstract

Cheng Skye H, Jian JJ, Chan KY, Tsai SY, Liu MC, Chen CM. The benefit and risk of postmastectomy radiation therapy in patients with high-risk breast cancer. Am J Clin Oncol 1998;21(1):12-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9499249&dopt;=Abstract

Chia SK, Ragaz J, Baird B, Jackson SM, Le N. Impact of isolated locoregional recurrence (ILR) in stage I-II breast cancer (BrCa) treated with mastectomy (M) and adjuvant chemotherapy (CT) with or without locoregional radiotherapy (RT): Results from the British Columbia (BC) studies [abstract]. Breast Cancer Res Treat 1999;57(1):107.

Christian MC, McCabe MS, Korn EL, Abrams JS, Kaplan RS, Friedman MA. The National Cancer Institute audit of the National Surgical Adjuvant Breast and Bowel Project Protocol B-06 . N Engl J Med 1995 Nov 30;333(22):1469-74. Comment in: N Engl J Med 1995 Nov 30;333(22):1496-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7477148&dopt;=Abstract

Clark RM, Whelan T, Levine M, Roberts R, Willan A, McCulloch P, Lipa M, Wilkinson RH, Mahoney LJ. Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: an update. Ontario Clinical Oncology Group. J Natl Cancer Inst 1996 Nov 20;88(22):1659-64. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8931610&dopt;=Abstract

Clinical outcomes of postoperative locoregional radiotherapy in premenopausal and postmenopausal chinese women with breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A372.

Clough KB, Nos C, Salmon RJ, Soussaline M, Durand J-C. Conservative treatment of breast cancers by mammaplasty and irradiation: A new approach to lower quadrant tumors. Plast Reconstr Surg 1995;96(2):363-70. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7624409&dopt;=Abstract

Cuzick J. Overview of adjuvant radiotherapy for breast cancer. Recent Results Cancer Res 1989;115:220-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=2696036&dopt;=Abstract

Cuzick J. Overview of adjuvant radiotherapy for breast cancer. Prog Clin Biol Res 1990;354B:227-32. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=2236169&dopt;=Abstract

Cuzick J, Stewart H, Rutqvist L, Houghton J, Edwards R, Redmond C, Peto R, Baum M, Fisher B, Host H, et al. Cause-specific mortality in long-term survivors of breast cancer who participated in trials of radiotherapy. J Clin Oncol 1994 Mar;12(3):447-53. Comment in: J Clin Oncol 1994 Mar;12(3):444-6; J Clin Oncol 1994 Jul;12(7):1525. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8120544&dopt;=Abstract

Datchary J, Tiberghien B, Nahra G, Ganaire JC. Concurrent chemo-radiotherapy (cc-rt) with mitoxantrone (m) as adjuvant treatment of breast cancer: 3-year follow-up results of a pilot study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A344.

Deigert F, Gunn W, Lindemann F, Stack T, Cherewick T. A blended beam technique to decrease toxic effects of post mastectomy irradiation by combining and sequentially mixing electrons and photons. Med Dosim 1995 Fall;20(3):183-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7576092&dopt;=Abstract

Denham JW, Hamilton CS, Christie D, O'Brien M, Bonaventura A, Stewart JF, Ackland SP, Lamb DS, Spry NA, Dady P, Atkinson CH, Wynne C, Joseph DJ. Simultaneous adjuvant radiation therapy and chemotherapy in high-risk breast cancer - toxicity and dose modification: A Trans-Tasman Radiation Oncology Group Multi-institution Study. Int J Radiat Oncol Biol Phys 1995;31(2):305-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7836084&dopt;=Abstract

Deutsch M, Bryant J, Bass G. Radiotherapy review on national surgical adjuvant breast and bowel project (NSABP) phase III breast cancer clinical trials: is there a need for submission of portal/simulation films? Am J Clin Oncol 1999 Dec;22(6):606-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10597746&dopt;=Abstract

Diab SG, deMoor CA, Clark GM, Osborne CK, Ravdin PM, Elledge RM. Radiation therapy improves survival by decreasing local failure in breast cancer patients with 10 or more positive axillary lymph nodes (aln) treated with mastectomy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A458.

Diab SG, Hilsenbeck SG, de Moor C, Clark GM, Osborne CK, Ravdin PM, Elledge RM. Radiation therapy and survival in breast cancer patients with 10 or more positive axillary lymph nodes treated with mastectomy. J Clin Oncol 1998 May;16(5):1655-60. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9586875&dopt;=Abstract

Du X, Freeman JL, Freeman DH, Syblik DA, Goodwin JS. Temporal and regional variation in the use of breast-conserving surgery and radiotherapy for older women with early-stage breast cancer from 1983 to 1995. J Gerontol A Biol Sci Med Sci 1999 Sep;54(9):M474-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10536651&dopt;=Abstract

Dunscombe PB, Samant RS, Roberts GH. A cost-outcome analysis of adjuvant post-mastectomy locoregional radiotherapy in premenopausal node-positive breast cancer patients. Int J Radiat Oncol Biol Phys 1999;45(3 Suppl):224-5.

El-Tamer M, Homel P, Braverman AS, Wolberg WH, Robins HI, Goldhirsch A, Coates AS, Colleoni M, Gelber RD, Raffle AE, Evans RA, Overgaard M, Rose C, Mouridsen H, Ragaz J, Jackson SM, Spinelli JJ, Hellman S. Radiotherapy and chemotherapy in high-risk breast cancer (1) [multiple letters]. New Engl J Med 1998 Jan 29;338(5):329-33. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9446029&dopt;=Abstract

Fentiman IS. Long-term follow-up of the first breast conservation trial: Guy's wide excision study. Breast 2000;9(1):5-8.

Fisher B, Anderson S, Redmond CK, Wolmark N, Wickerham DL, Cronin WM. Reanalysis and results after 12 years of follow-up in a randomized clinical trial comparing total mastectomy with lumpectomy with or without irradiation in the treatment of breast cancer. New Engl J Med 1995;333(22):1456-61. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7477145&dopt;=Abstract

Fisher BJ, Perera FE, Cooke A, Opeitum A, Dar AR, Venkatesan VM, Stitt L, Radwan JS. Extracapsular axillary node extension in patients receiving adjuvant systemic therapy: An indication radiotherapy. Int J Radiat Oncol Biol Phys 1997;38(3):551-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9231679&dopt;=Abstract

Fowble B. Postmastectomy radiation in patients with one to three positive axillary nodes receiving adjuvant chemotherapy: An unresolved issue. Semin Radiat Oncol 1999 Jul;9(3):230-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378961&dopt;=Abstract

Fowble B. Postmastectomy radiation: then and now. Oncology (Huntingt) 1997 Feb;11(2):213-34, 239; discussion 239-40, 243. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9057176&dopt;=Abstract

Freedman GM, Fowble BL, Hanlon AL, Fein DA, Hoffman JP, Sigurdson ER, Goldstein LJ. Postmastectomy radiation and adjuvant systemic therapy: Outcomes in high-risk women with stage II-III breast cancer and assessment of clinical, pathologic, and treatment-related factors influencing local-regional control. Breast J 1997;3(6):337-44.

Gaffney DK, Prows J, Leavitt DD, Egger MJ, Morgan JG, Stewart JR. Electron arc irradiation of the postmastectomy chest wall: clinical results. Radiother Oncol 1997 Jan;42(1):17-24. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9132821&dopt;=Abstract

Galper S, Recht A, Silver B, Manola J, Gelman R, Schnitt SJ, Connolly JL, Harris JR. Factors associated with regional nodal failure in patients with early stage breast cancer with 0-3 positive axillary nodes following tangential irradiation alone. Int J Radiat Oncol Biol Phys 1999;45(5):1157-66. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10613308&dopt;=Abstract

Geisler DP, Boyle MJ, Malnar KF, Melichar RM, McGee JM, Nolen MG, Broughan TA. Adjuvant radiation after modified radical mastectomy for breast cancer fails to prolong survival. Am Surg 2000 May;66(5):452-8; discussion 458-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10824745&dopt;=Abstract

Goy JC, Dobbs HJ. Variation in postoperative radiotherapy delivery for patients with screen-detected breast cancer in the south Thames (east) Region. Clin Oncol (R Coll Radiol) 1998;10(1):30-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9543612&dopt;=Abstract

Gruenberger T, Gorlitzer M, Soliman T, Rudas M, Mittlboeck M, Gnant M, Reiner A, Teleky B, Seitz W, Jakesz R. It is possible to omit postoperative irradiation in a highly selected group of elderly breast cancer patients. Breast Cancer Res Treat 1998 Jul;50(1):37-46. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9802618&dopt;=Abstract

Gustavsson A, Bendahl PO, Cwikiel M, Eskilsson J, Thapper KL, Pahlm O. No serious late cardiac effects after adjuvant radiotherapy following mastectomy in premenopausal women with early breast cancer. Int J Radiat Oncol Biol Phys 1999 Mar 1;43(4):745-54. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10098429&dopt;=Abstract

Hardenbergh PH, Bentel GC, Prosnitz LR, Marks LB. Postmastectomy radiotherapy: toxicities and techniques to reduce them. Semin Radiat Oncol 1999 Jul;9(3):259-68. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378965&dopt;=Abstract

Harrigan P, Otis D, Recht A, Gelman R, Hauptman P, Hayes D, Henderson IC, Harris JR, Shapiro C. The effect of adjuvant radiation therapy (rt) on cardiac events in breast cancer patients treated with doxorubicin (dox) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A109.

Harris JR, Halpin-Murphy P, McNeese M, Mendenhall NP, Morrow M, Robert NJ. Consensus statement on postmastectomy radiation therapy. Int J Radiat Oncol Biol Phys 1999;44(5):989-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10421530&dopt;=Abstract

Hayman JA, Hillner BE. Is the use of radiation therapy after mastectomy cost-effective? Semin Radiat Oncol 1999 Jul;9(3):287-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378968&dopt;=Abstract

Helinto M, Blomqvist C, Heikkila P, Joensuu H. Post-mastectomy radiotherapy in pT3N0M0 breast cancer: is it needed? Radiother Oncol 1999 Sep;52(3):213-7. Comment in: Radiother Oncol 1999 Sep;52(3):203-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10580866&dopt;=Abstract

Hetelekidis S, Schnitt SJ, Silver B, Manola J, Bornstein BA, Nixon AJ, Recht A, Gelman R, Harris JR, Connolly JL. The significance of extracapsular extension of axillary lymph node metastases in early-stage breast cancer. Int J Radiat Oncol Biol Phys 2000;46(1):31-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10656369&dopt;=Abstract

Hjris I, Sand NP, Andersen J, Rehling M, Overgaard M. Myocardial perfusion imaging in breast cancer patients treated with or without post-mastectomy radiotherapy. Radiother Oncol 2000 May;55(2):163-72. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10799728&dopt;=Abstract

Hoeller U, Hoecht St, Runkel S, Nausner M, Hinkelbein W. Radiotherapy of male breast cancer. Onkologie 1999;22(4):304-7.

Hojris I, Overgaard M, Christensen JJ, Overgaard J. Morbidity and mortality of ischaemic heart disease in high-risk breast-cancer patients after adjuvant postmastectomy systemic treatment with or without radiotherapy: analysis of DBCG 82b and 82c randomised trials. Radiotherapy Committee of the Danish Breast Cancer Cooperative Group. Lancet 1999 Oct 23;354(9188):1425-30. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10543669&dopt;=Abstract

Hsi RA, Antell A, Schultz DJ, Solin LJ. Radiation therapy for chest wall recurrence of breast cancer after mastectomy in a favorable subgroup of patients. Int J Radiat Oncol Biol Phys 1998 Oct 1;42(3):495-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9806506&dopt;=Abstract

Igarashi T, Itoh K, Fujii H, Ohtsu T, Minami H, Sasaki Y, Shimizu W, Ogino T, Muramatsu M. Successful treatment by radiation and hormone therapy of isolated local recurrence of breast cancer 24 years after mastectomy accompanied by immune thrombocytopenia: a case report. Jpn J Clin Oncol 1998 Apr;28(4):270-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9657014&dopt;=Abstract

Jacobson JA, Danforth DN, Cowan KH, d'Angelo T, Steinberg SM, Pierce L, Lippman ME, Lichter AS, Glatstein E, Okunieff P. Ten-year results of a comparison of conservation with mastectomy in the treatment of stage I and II breast cancer. N Engl J Med 1995 Apr 6;332(14):907-11. Comment in: N Engl J Med 1995 Apr 6;332(14):951-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7877647&dopt;=Abstract

Janov AJ, Tulecke M, O'Neill A, Lester S, Mauch P, Harris J, Schnitt S, Shapiro CL. Clinical and pathologic features of breast cancers (bc) in women treated for hodgkin's disease (hd): a case-control study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A570.

Jansson T, Lindman H, Nyg~ard K, Dahlgren CV, Montelius A, Oberg-Kreuger C, Asplund S, Bergh J. Radiotherapy of breast cancer after breast-conserving surgery: an improved technique using mixed electron-photon beams with a multileaf collimator. Radiother Oncol 1998 Jan;46(1):83-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9488131&dopt;=Abstract

Kingston RD, Bridger J, Smith CJ, Jeacock J, Robinson C. Axillary sampling and radiotherapy does not compromise the patient with early breast cancer: Trafford database experience. Eur J Surg Oncol 1995 Aug;21(4):364-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7664899&dopt;=Abstract

Kraemer O, Andersen M, Siim E. Breast reconstruction and tissue expansion in irradiated versus not irradiated women after mastectomy. Scand J Plast Reconstr Surg Hand Surg 1996 Sep;30(3):201-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8885015&dopt;=Abstract

Kuhnt T, Richter C, Enke H, Dunst J. Acute radiation reaction and local control in breast cancer patients treated with postmastectomy radiotherapy. Strahlenther Onkol 1998 May;174(5):257-61. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9614954&dopt;=Abstract

Kunkler IH. Benefits of post-mastectomy radiotherapy [letter]. Lancet 1998 Jan 17;351(9097):219. Comment on: Lancet 1997 Nov 15;350(9089):1415-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9449902&dopt;=Abstract

Kunkler IH. Postoperative radiotherapy in high-risk postmenopausal breast cancer [letter]. Lancet 1999 Sep 4;354(9181):865; discussion 866. Comment on: Lancet 1999 May 15;353(9165):1641-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10485749&dopt;=Abstract

Kuske RR. Adjuvant irradiation after mastectomy in women with one to three positive axillary nodes: then no; now yes. Semin Radiat Oncol 1999 Jul;9(3):254-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378964&dopt;=Abstract

Kuske RR, Sanchez M, Farr GH, Moroz K, Hayden D, Fineberg BB, Jiang X. Extracapsular axillary nodal extension (ECE) in breast cancer: patterns of recurrence, arm edema, and survival after mastectomy with and without irradiation [abstract]. Int J Radiat Oncol Biol Phys 1999;45(3 Suppl):157.

Lamb D, Atkinson C, Joseph D, O'Brien P, Ackland S, Bonaventura A, Dady P, Hamilton C, Spry N, Stewart J, Denham J. Simultaneous adjuvant radiotherapy and chemotherapy for stage I and II breast cancer. Australas Radiol 1999;43(2):220-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10901906&dopt;=Abstract

Leask DE. Radical choices in mastectomy [letter]. CMAJ 1997 Apr 15;156(8):1119, 1121. Comment on: Can Med Assoc J 1997 Jan 1;156(1):43-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9141981&dopt;=Abstract

Lee JH, Solin LJ, Glick HA. A decision-analytic model and cost-effectiveness evaluation of postmastectomy radiation therapy for high-risk breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A1621.

Lirette A, Pouliot J, Aubin M, Larochelle M. The role of electronic portal imaging in tangential breast irradiation: a prospective study. Radiother Oncol 1995 Dec;37(3):241-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8746594&dopt;=Abstract

Marini G, Micheletti E, Simoncini E, Face B L, Ferrari VD, Husher A, Catalano G, Ambrosi E. Historical comparison between postmastectomy radiotherapy (rt) plus concomitant adjuvant chemotherapy (act) and chemotherapy alone in premenopausal breast cancer patient with positive axillary nodes [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A603.

Marks LB, Hardenbergh PH, Winer ET, Prosnitz LR. Assessing the cost-effectiveness of postmastectomy radiation therapy. Int J Radiat Oncol Biol Phys 1999 Apr 1;44(1):91-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10219800&dopt;=Abstract

McNeil C. Postmastectomy radiation: back to center stage? J Natl Cancer Inst 1999 Nov 3;91(21):1800-1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10610404&dopt;=Abstract

Meakin JW, Hayward JL, Panzarella T, Allt WE, Beale FA, Bulbrook RD, Bush RS, Clark RM, Fitzpatrick PJ, Hawkins NV, Jenkin RD, Pringle JF, Rider WD. Ovarian irradiation and prednisone following surgery and radiotherapy for carcinoma of the breast. Breast Cancer Res Treat 1996;37(1):11-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8750523&dopt;=Abstract

Metz JM, Schultz D, Fox K, Glick J, Solin LJ. Long term outcome after postmastectomy radiation therapy for breast cancer patients at high risk for local-regional recurrence [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A462.

Metz JM, Schultz D, Fox K, Matthews A, Glick J, Solin LJ. Analysis of outcomes for high risk breast cancer patients based on interval from surgery to postmastectomy radiation therapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A285.

Metz JM, Schultz DJ, Fox K, Glick J, Solin LJ. Long-term outcome after postmastectomy radiation therapy for breast cancer patients at high risk for local-regional recurrence. Cancer J Sci Am 1999 Mar-Apr;5(2):77-83. Comment in: Cancer J Sci Am 1999 Mar-Apr;5(2):70-2. Available from: http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10198729&dopt;=Abstract

Micheletti E, La Face B, Huscher A, Catalano G, Ambrosi E, Marini G, Simoncini E. Postmastectomy radiotherapy and concomitant adjuvant chemotherapy versus adjuvant chemotherapy alone in premenopausal breast cancer patients with positive axillary nodes. Tumori 1998 Nov-Dec;84(6):652-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10080670&dopt;=Abstract

Mok TS, Kwan WH, Yeo WM, Chan AT, Chan EC, Chak K, Chow DL, Lo C, Leung TW, Teo PM. Clinical outcomes of post-operative locoregional radiotherapy in pre-menopausal and post-menopausal Chinese women with breast cancer. Radiother Oncol 2000;54(3):201-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10738077&dopt;=Abstract

Mokbel K, Reed MJ. Benefits of post-mastectomy radiotherapy [letter]. Lancet 1998 Jan 17;351(9097):219. Comment on: Lancet 1997 Nov 15;350(9089):1415-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9449901&dopt;=Abstract

Morris AD, Morris RD, Wilson JF, White J, Steinberg S, Okunieff P, Arriagada R, Le MG, Blichert Toft M, van Dongen JA. Breast-conserving therapy vs mastectomy in early-stage breast cancer: a meta-analysis of 10-year survival. Cancer J Sci Am 1997 Jan-Feb;3(1):6-12. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9072310&dopt;=Abstract

Morrow M. Postmastectomy radiation therapy: A surgical perspective. Semin Radiat Oncol 1999 Jul;9(3):269-74. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378966&dopt;=Abstract

Norum J. Postmastectomy radiotherapy, axillary lymph node dissection and oestrogen receptor status predict prognosis [letter]. Eur J Cancer 1995 Sep;31A(10):1714. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7488431&dopt;=Abstract

Obedian E, Haffty BG. Internal mammary nodal irradiation in conservatively-managed breast cancer patients: is there a benefit? Int J Radiat Oncol Biol Phys 1999 Jul 15;44(5):997-1003. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10421532&dopt;=Abstract

Overgaard M. Overview of randomized trials in high risk breast cancer patients treated with adjuvant systemic therapy with or without postmastectomy irradiation. Semin Radiat Oncol 1999 Jul;9(3):292-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378969&dopt;=Abstract

Overgaard M, Hansen PS, Overgaard J, Rose C, Andersson M, Bach F, Kjaer M, Gadeberg CC, Mouridsen HT, Jensen MB, Zedeler K. Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial. N Engl J Med 1997 Oct 2;337(14):949-55. Comment in: N Engl J Med 1997 Oct 2;337(14):996-7; N Engl J Med 1998 Jan 29;338(5):329; discussion 331-2; N Engl J Med 1998 Jan 29;338(5):329-30; discussion 331-2; N Engl J Med 1998 Jan 29;338(5):330-1; discussion 331-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9395428&dopt;=Abstract

Overgaard M, Jensen MB, Overgaard J, Hansen PS, Rose C, Andersson M, Kamby C, Kjaer M, Gadeberg CC, Rasmussen BB, Blichert-Toft M, Mouridsen HT. Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Lancet 1999 May 15;353(9165):1641-8. Comment in: Lancet 1999 Sep 4;354(9181):865; discussion 866; Lancet 1999 Sep 4;354(9181):865-6; discussion 866; Lancet 1999 Dec 4;354(9194):1998-9; discussion 1999; Lancet 1999 Dec 4;354(9194):2002. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10335782&dopt;=Abstract

Patton ML, Moss BE, Kraut JD, Germain TJ, Haith LR Jr, Shotwell BA, Reilly KJ. Underutilization of breast-conservation surgery with radiation therapy for women with stage Tis, I or II breast cancer. Int Surg 1996 Oct-Dec;81(4):423-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9127811&dopt;=Abstract

Peiro G, Bornstein BA, Connolly JL, Gelman R, Hetelekidis S, Nixon AJ, Recht A, Silver B, Harris JR, Schnitt SJ. The influence of infiltrating lobular carcinoma on the outcome of patients treated with breast-conserving surgery and radiation therapy. Breast Cancer Res Treat 2000 Jan;59(1):49-54. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10752679&dopt;=Abstract

Pierce LJ, Lichter AS. Defining the role of post-mastectomy radiotherapy: the new evidence. Oncology (Huntingt) 1996 Jul;10(7):991-1002; discussion 1006-7, 1011. Comment in: Oncology (Huntingt) 1996 Nov;10(11):1610. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8837118&dopt;=Abstract

Raqaz J, Jackson S, Le N, Plenderleith IH, Spinelli J, Wilson K, Knowling M, Olivotto I, Coldman A. Can adjuvant locoregional radiotherapy (xrt) reduce systemic recurrences in stage i-ii breast cancer patients? Recurrence analysis of the british columbia randomized trial [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A150.

Robert NJ. Role of postmastectomy radiotherapy: A medical oncology perspective. Semin Radiat Oncol 1999 Jul;9(3):241-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378962&dopt;=Abstract

Rutqvist LE. Radiation therapy as an adjunct to primary surgery in early stage breast cancer: biological and clinical rationale. Semin Radiat Oncol 1999 Jul;9(3):217-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378959&dopt;=Abstract

Sauer R. Adjuvant radiotherapy after breast conserving surgery for breast cancer. Pro. Eur J Cancer 2000;36(9):1073-8. Available from: http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10854937&dopt;=Abstract

Shikama N, Oguchi M, Sone S, Arakawa K, Oohata T, Moriya K, Okazaki Y, Takei K, Sasaki S, Gomi K. Radiotherapy following mastectomy: indication and contraindication of chest wall irradiation. Int J Radiat Oncol Biol Phys 1999;44(5):991-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10421531&dopt;=Abstract

Skoczylas JZ, Bentzen SM, Overgaard M, Overgaard J. Time course of radiological lung density changes after postmastectomy radiotherapy. Acta Oncol 2000;39(2):181-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10859008&dopt;=Abstract

Spear SL, Onyewu C. Staged breast reconstruction with saline-filled implants in the irradiated breast: recent trends and therapeutic implications. Plast Reconstr Surg 2000;105(3):930-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10724252&dopt;=Abstract

Strom EA, McNeese MD. Postmastectomy irradiation: rationale for treatment field selection. Semin Radiat Oncol 1999 Jul;9(3):247-53. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10378963&dopt;=Abstract

Taghian AG, Powell SN. The role of radiation therapy for primary breast cancer. Surg Clin North Am 1999 Oct;79(5):1091-115. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10572553&dopt;=Abstract

Tralins AH. Lactation after conservative breast surgery combined with radiation therapy. Am J Clin Oncol 1995 Feb;18(1):40-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7847257&dopt;=Abstract

Ulutin C, Guden M, Surenkok S, Pak Y. Fifteen cases of male breast carcinoma treated between 1980 and 1995. Radiat Med 1998 Sep-Oct;16(5):383-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9862164&dopt;=Abstract

van de Steene J, Storme G. Meta-analysis of breast cancer surgery trials confirms significant factors for overall survival benefit due to adjuvant radiotherapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A279.

Vanuytsel L. The crucial role of adjuvant irradiation after surgery for breast cancer. Crit Rev Oncol Hematol 1999 Aug;31(3):225-38. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10532197&dopt;=Abstract

Vishwanathan N, Bhaskar N, Supe SS, Swamy K, Ravichandran R, Kannan V, Ramesh C. Role of electron beam treatment in postoperative management of carcinoma of the breast. Indian J Cancer 1998;35(1):1-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9847464&dopt;=Abstract

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Yarnold J. Benefits of post-mastectomy radiotherapy. Lancet 1997 Nov 15;350(9089):1415-6. Comment in: Lancet 1998 Jan 17;351(9097):219. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9371162&dopt;=Abstract

Young WW, Marks SM, Kohler SA, Hsu AY. Dissemination of clinical results. Mastectomy versus lumpectomy and radiation therapy. Med Care 1996 Oct;34(10):1003-17. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8843927&dopt;=Abstract

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## 6. Treatment-Related Side Effects and Quality of Life Issues

### 6a. Overviews

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Anderson T, Bardin CW, Barrett-Conner E, Black C, Borwhat M, Burger H, Clarkson T, Cobleigh M, Cosman F, Douglas MS, Dunaif A, Ford J, Ganz P, Gleason S, Goodwin P, Goss P, Green B, Gretz E, Harvey J, Hazzard W, Helzlsouer K, Jordan VC, Josse R, Kelaghan J, Kleerekoper M, Lewis J, Llewellyn-Thomas H, Loprinzi C, Mark M, Martin A, Martin H, Miesfeldt S, Moore M, Nachtigall L, New M, O'Connor A, Olsen M, Parker B, Parnes H, Perlman J, Pinkerton J, Powles T, Prior J, Pritchard K, Ragaz J, Railey E, Rumen N, Ropka M, Ross RK, Santen R, Sawka C, Sellin R, Slingluff C, Swain S, Tysenhouse P, Watts N, Whamond E, Wills M. Treatment of estrogen deficiency symptoms in women surviving breast cancer. J Clin Endocrinol Metab 1998 Jun;83(6):1993-2000. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9626130&dopt;=Abstract

Ashing-Giwa K, Ganz PA, Petersen L. Quality of life of african-american and white long term breast carcinoma survivors. Cancer 1999;85(2):418-26. Published erratum appears in Cancer 1999 Aug 15;86(4):732-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10023710&dopt;=Abstract

Atkins CD, Perlman JA, Johnson K, Nayfield S, Ford LG, Vassilopoulou- Sellin R, Prosnitz LR, Golden L, Stadel B, Cobleigh MA, Berris RF, Bush T, Davidson NE, Robert NJ, Sparano JA, Tormey DC, Wood WC. Estrogen replacement therapy in breast cancer survivors (3). JAMA 1995 Feb 22;273(8):619-21. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7844866&dopt;=Abstract

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Hurny C, Bernhard J, Coates AS, Castiglione-Gertsch M, Peterson HF, Gelber RD, Forbes JF, Rudenstam C, Simoncini E, Crivellari D, Goldhirsch A, Senn H. Impact of adjuvant therapy on quality of life in women with node-positive operable breast cancer. Lancet 1996 May 11;347(9011):1279-84. Published erratum appears in Lancet 1997 Jul 26;350(9073):298. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8622502&dopt;=Abstract

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Longman AJ, Braden CJ, Mishel MH. Side-effects burden, psychological adjustment, and life quality in women with breast cancer: pattern of association over time. Oncol Nurs Forum 1999 Jun;26(5):909-15. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10382190&dopt;=Abstract

Lyman GH, Kuderer NM, Lyman SL, Debus M, Minton S, Balducci L, Horton J, Reintgen D, Cox C. Survival following early versus late recurrence of breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A633.

Marcus AC, Garrett KM, Cella D, Wenzel LB, Brady MJ, Crane LA, McClatchey MW, Kluhsman BC, Pate-Willig M. Telephone counseling of breast cancer patients after treatment: a description of a randomized clinical trial. Psychooncology 1998 Nov-Dec;7(6):470-82. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9885088&dopt;=Abstract

Massie MJ. Quality of life and psycho-social support for women with breast cancer [abstract]. Paper presented at: Perspectives in Breast Cancer; 1995 Sep 29-30; Phoenix, Arizona.

Mathe G. Possible respect of patient quality of life--without reducing survival expectancy--in breast cancer treatment [editorial]. Biomed Pharmacother 1998;52(3):97-100. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9755801&dopt;=Abstract

McQuellon RP, Kimmick G, Hurt GJ. Quality-of-life measurement in women with breast cancer. Breast J 1997;3(4):178-86.

Meek AG. Breast radiotherapy and lymphedema. Cancer 1998 Dec 15;83(12 Suppl American):2788-97. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9874399&dopt;=Abstract

Mock V, Dow KH, Meares CJ, Grimm PM, Dienemann JA, Haisfield-Wolfe ME, Quitasol W, Mitchell S, Chakravarthy A, Gage I. Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer. Oncol Nurs Forum 1997 Jul;24(6):991-1000. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9243585&dopt;=Abstract

Moritz S, Bellenger K, Riley D, Houghton J, Fallowfield L, Saunders C. Feasibility of measuring quality of life in an adjuvant breast trial [abstract]. Br J Cancer 1996;74 Suppl 28:31.

Munro AJ, Potter S. A quantitative approach to the distress caused by symptoms in patients treated with radical radiotherapy. Br J Cancer 1996 Aug;74(4):640-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8761383&dopt;=Abstract

Neugut AI, Weinberg MD, Ahsan H, Rescigno J. Carcinogenic effects of radiotherapy for breast cancer. Oncology (Huntingt) 1999 Sep;13(9):1245-56; discussion 1257, 1261-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10509322&dopt;=Abstract

Nezu CM, Nezu AM, Friedman SH, Houts PS, DelliCarpini LA, Bildner C, Faddis S. Cancer and psychological distress: two investigations regarding the role of social problem-solving. J Psychosoc Oncol 1999;16(3-4):27-40.

Northouse LL, Caffey M, Deichelbohrer L, Schmidt L, Guziatek-Trojniak L, West S, Kershaw T, Mood D. The quality of life of African American women with breast cancer. Res Nurs Health 1999 Dec;22(6):449-60. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10630287&dopt;=Abstract

Olschewski M, de Haes JC, Jonat W, Kaufmann M, Schumacher M, Kolvenbag G. Quality-of-life assessment in an international randomized trial of temporary ovarian ablation vs cmf in early breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A1638.

Palazzi M, Asnaghi D, Baroncelli G, Cavallini D, De Tomasi D, Guzzetti R, Meregalli S, Morrica B, Pradella R, Valli M. Are international guidelines on adjuvant treatment for early breast cancer followed in clinical practice? A multicenter observational study on 1547 patients treated in 1997 [abstract]. Eur J Cancer 1999;35 Suppl 4:S229.

Pendlebury SC, Bilous M, Langlands AO. Sarcomas following radiation therapy for breast cancer: a report of three cases and a review of the literature. Int J Radiat Oncol Biol Phys 1995 Jan 15;31(2):405-10. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7836096&dopt;=Abstract

Perlman JA, Parnes HL, Ford LG. Projections of the longevity effects of tamoxifen (tam) + progestin (t+p) versus hormone replacement therapy (hrt) in breast cancer survivors requiring hormonal symptom relief [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A462.

Perrone F, De Placido S, Gallo C, Carlomagno C, Lauria R, Bianco AR. Adjuvant chemoendocrine therapy for early breast cancer: is it worthwhile? [review]. Int J Oncol 1995;7(5):1129-37.

Pyrhonen S, Ellmen J, Vuorinen J, Gershanovich M, Tominaga T, Kaufmann M, Hayes DF. Meta-analysis of trials comparing toremifene with tamoxifen and factors predicting outcome of antiestrogen therapy in postmenopausal women with breast cancer. Breast Cancer Res Treat 1999 Jul;56(2):133-43. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10573106&dopt;=Abstract

Roy JA, Piccart MJ. Adjuvant systemic therapy for breast cancer. Curr Opin Oncol 1995 Nov;7(6):517-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8547399&dopt;=Abstract

Rubagotti A, Perrotta A, Casella C, Boccardo F. Risk of new primaries after chemotherapy and/or tamoxifen treatment for early breast cancer. Ann Oncol 1996 Mar;7(3):239-44. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8740786&dopt;=Abstract

Saarto T, Blomqvist C, Valimaki M, Makela P, Sarna S, Elomaa I. Clodronate improves bone mineral density in post-menopausal breast cancer patients treated with adjuvant antioestrogens. Br J Cancer 1997;75(4):602-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9052418&dopt;=Abstract

Sabbioni ME, Castiglione M, Hurny C, Siegrist HP, Bacchi M, Bernhard J, Thurlimann B, Bonnefoi H, Perey L, Goldhirsch A, Senn HJ. Interaction of tamoxifen with concurrent cytotoxic adjuvant treatment affects lymphocytes and lymphocyte subsets counts in breast cancer patients. Support Care Cancer 1999 May;7(3):149-53. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10335933&dopt;=Abstract

Sasco AJ, Chaplain G, Amoros E, Saez S. Endometrial cancer following breast cancer: Effect of tamoxifen and castration by radiotherapy. Epidemiology 1996 Jan;7(1):9-13. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8664408&dopt;=Abstract

Schover LR. Psychosexual issues in pre-menopausal breast cancer [abstract]. Paper presented at: 12th Annual International Breast Cancer Conference; 1995 Mar 16-18; Miami, FL.

Schulz U, Gokel JM, Poleska W. Soft tissue sarcomas after radiation treatment for breast cancer. Three case studies and review of literature. Strahlenther Onkol 2000 Mar;176(3):144-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10742836&dopt;=Abstract

Schunemann H, Willich N. Lymphoedema of the arm after primary treatment of breast cancer. Anticancer Res 1998 May-Jun;18(3C):2235-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9703792&dopt;=Abstract

Segal R, Reid R, Johnson D, Laplante J, Colletta S, Harrison M, Smith A, Evans WK. Pilot study of physical fitness and quality of life in patients with breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A234.

Seidman AD, Portenoy R, Yao TJ, Lepore J, Mont EK, Kortmansky J, Onetto N, Ren L, Grechko J, Beltangady M, Usakewicz J, Souhrada M, Houston C, McCabe M, Salvaggio R, Thaler H, Norton L. Quality of life in phase II trials: a study of methodology and predictive value in patients with advanced breast cancer treated with paclitaxel plus granulocyte colony-stimulating factor. J Natl Cancer Inst 1995;87(17):1316-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7544834&dopt;=Abstract

Shapiro CL, Hardenbergh PH, Gelman R, Blanks D, Hauptman P, Recht A, Hayes DF, Harris J, Henderson IC. Cardiac effects of adjuvant doxorubicin and radiation therapy in breast cancer patients. J Clin Oncol 1998 Nov;16(11):3493-501. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9817266&dopt;=Abstract

Sheerin N, Bourke JF, Holder J, North J, Burns DA. Bullous pemphigoid following radiotherapy. Clin Exp Dermatol 1995 Jan;20(1):80-2. Comment in: Clin Exp Dermatol 1995 Jul;20(4):360-1; Clin Exp Dermatol 1995 Jul;20(4):361. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7671407&dopt;=Abstract

Spencer SM, Lehman JM, Wynings C, Arena P, Carver CS, Antoni MH, Derhagopian RP, Ironson G, Love N. Concerns about breast cancer and relations to psychosocial well-being in a multiethnic sample of early-stage patients. Health Psychol 1999 Mar;18(2):159-68. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10194051&dopt;=Abstract

Subramanian S, Goker H, Kanji A, Sweeney H. Clinical adrenal insufficiency in patients receiving megestrol therapy. Arch Intern Med 1997 May 12;157(9):1008-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9140272&dopt;=Abstract

Sugden EM, Rezvani M, Harrison JM, Hughes LK. Shoulder movement after the treatment of early stage breast cancer. Clin Oncol (R Coll Radiol) 1998;10(3):173-81. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9704180&dopt;=Abstract

Svane G, Rotstein S, Lax I. Influence of radiation therapy on lung tissue in breast cancer patients. CT-assessed density changes 4 years after completion of radiotherapy. Acta Oncol 1995;34(6):845-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7576754&dopt;=Abstract

Tasmuth T, Kataja M, Blomqvist C, von Smitten K, Kalso E. Treatment-related factors predisposing to chronic pain in patients with breast cancer--a multivariate approach. Acta Oncol 1997;36(6):625-30. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9408154&dopt;=Abstract

Taylor ME, Perez CA, Halverson KJ, Kuske RR, Philpott GW, Garcia DM, Mortimer JE, Myerson RJ, Radford D, Rush C. Factors influencing cosmetic results after conservation therapy for breast cancer. Int J Radiat Oncol Biol Phys 1995 Feb 15;31(4):753-64. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7860386&dopt;=Abstract

ten Vergert EM, Rodenhuis S, Bontenbal M, Richel DJ, Schornagel JH, Mulder NH, Wagstaff J, Rodenburg CJ, Blijham GH, de Wit R, Nooy MA, Beex LV, Hupperets PS, de Vries EG. Quality of life in a randomized adjuvant breast carcinoma study with standard vs high dose chemotherapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A77.

Travis LB, Curtis RE, Inskip PD, Hankey BF. Re: Lung cancer risk and radiation dose among women treated for breast cancer [letter]. J Natl Cancer Inst 1995 Jan 4;87(1):60-1. Comment on: J Natl Cancer Inst 1994 Jul 6;86(13):983-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7666469&dopt;=Abstract

Treatment of estrogen deficiency symptoms in women surviving breast cancer. Part 2: Hormone replacement therapy and breast cancer. Oncology (Huntingt) 1999 Feb;13(2):245-8, 251-4, 257 passim. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10079474&dopt;=Abstract

Treatment of estrogen deficiency symptoms in women surviving breast cancer. Part 5: Selective estrogen receptor modulators and hormone replacement therapy. Proceedings of a conference. Charlottesville, Virginia, USA. September 21-23, 1997. Oncology (Huntingt) 1999 May;13(5):721-4, 727-8, 731-2 passim. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10356689&dopt;=Abstract

Trudeau ME. The problem of recurrent breast cancer and current second line therapies [abstract]. Can J Inf Dis 1995;6 Suppl C:261C.

Turesson I, Nyman J, Holmberg E, Oden A. Prognostic factors for acute and late skin reactions in radiotherapy patients. Int J Radiat Oncol Biol Phys 1996;36(5):1065-75. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8985028&dopt;=Abstract

Untch M, Kahlert S, Thomssen C, Sattler D, Kuhn W. Therapy-induced anaemia with dose-intensified (DI) chemotherapy (CT) - clinical relevance in the adjuvant treatment of breast cancer patients (PTS) [abstract]. Breast Cancer Res Treat 1999;57(1):46.

van der Wall E, Schaake-Koning CC, van Zandwijk N, Baars JW, Schornagel JH, Richel DJ, Rutgers EJ, Borger JH, Beijnen JH, Rodenhuis S. The toxicity of radiotherapy following high-dose chemotherapy with peripheral blood stem cell support in high-risk breast cancer: a preliminary analysis. Eur J Cancer 1996 Aug;32A(9):1490-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8911107&dopt;=Abstract

van Laar JM, Holscher HC, van Krieken JH, Stolk J. Bronchiolitis obliterans organizing pneumonia after adjuvant radiotherapy for breast carcinoma. Respir Med 1997 Apr;91(4):241-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9156149&dopt;=Abstract

Vehmanen L, Saarto T, Blomqvist C, Virkkunen P, Elomaa I. The effect of adjuvant clodronate on bone mineral density (BMD) in pre- and postmenopausal breast cancer patients. A randomized 5 yr. follow-up study [abstract]. Eur J Cancer 1999;35 Suppl 4:S159.

Vesoulis Z, Cunliffe C. Fine-needle aspiration biopsy of postradiation epithelioid angiosarcoma of breast. Diagn Cytopathol 2000 Mar;22(3):172-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10679998&dopt;=Abstract

Wenzel LB, Fairclough DL, Brady MJ, Cella D, Garrett KM, Kluhsman BC, Crane LA, Marcus AC. Age-related differences in the quality of life of breast carcinoma patients after treatment. Cancer 1999 Nov 1;86(9):1768-74. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10547550&dopt;=Abstract

Wiernik PH, Schleider MA, Gold EG. Breast cancer (bca) and non-hodgkin's lymphoma (nhl): does one lead to the other in some patients (pts) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A1262.

Williams JK, Carlson GW, Bostwick J 3rd, Bried JT, Mackay G. The effects of radiation treatment after TRAM flap breast reconstruction. Plast Reconstr Surg 1997 Oct;100(5):1153-60. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9326776&dopt;=Abstract

Woo B, Dibble SL, Piper BF, Keating SB, Weiss MC. Differences in fatigue by treatment methods in women with breast cancer. Oncol Nurs Forum 1998 Jun;25(5):915-20. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9644708&dopt;=Abstract

Yang FE, Vaida F, Heimann R, Mundt AJ, Nautiyal J, Vijayakumar S, Awan A. Influence of preirradiation chemotherapy on acute hematopoietic toxicity during adjuvant radiotherapy for stage i and ii breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A1661.

Yeo W, Teo PM, Wing HK, Suen M. Desmoid tumor mimicking local recurrence of carcinoma of the breast. Int J Clin Oncol 1998;3(1):49-51.

Young-McCaughan S. Sexual functioning in women with breast cancer after treatment with adjuvant therapy. Cancer Nurs 1996 Aug;19(4):308-19. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8768689&dopt;=Abstract

Yule GJ, Concannon MJ, Croll G, Puckett CL. Is there liability with chemotherapy following immediate breast construction? Plast Reconstr Surg 1996 Apr;97(5):969-73. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8619000&dopt;=Abstract

Zimmerman RP, Mark RJ, Kim AI, Walton T, Sayah D, Juillard GF, Nguyen M. Radiation tolerance of transverse rectus abdominis myocutaneous-free flaps used in immediate breast reconstruction. Am J Clin Oncol 1998 Aug;21(4):381-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9708638&dopt;=Abstract

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### 6b. Tamoxifen

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Abadi MA, Barakat RR, Saigo PE. Effects of tamoxifen on cervicovaginal smears from patients with breast cancer. Acta Cytol 2000 Mar-Apr;44(2):141-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10740597&dopt;=Abstract

Achiron R, Lipitz S, Sivan E, Goldenberg M, Horovitz A, Frenkel Y, Mashiach S. Changes mimicking endometrial neoplasia in postmenopausal, tamoxifen-treated women with breast cancer: a transvaginal Doppler study. Ultrasound Obstet Gynecol 1995 Aug;6(2):116-20. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8535913&dopt;=Abstract

Adami HO, Bergstrom R, Weiderpass E, Persson I, Barlow L, McLaughlin JK. Risk for endometrial cancer following breast cancer: a prospective study in Sweden. Cancer Causes Control 1997 Nov;8(6):821-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9427424&dopt;=Abstract

Ah-Song R, Sasco AJ. Tamoxifen and ocular toxicity. Cancer Detect Prev 1997;21(6):522-31. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9398992&dopt;=Abstract

Andersson M, Storm HH, Mouridsen HT. Carcinogenic effects of adjuvant tamoxifen treatment and radiotherapy for early breast cancer. Acta Oncol 1992;31(2):259-63. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1622643&dopt;=Abstract

Andersson M, Storm HH, Mouridsen HT. Endometrial carcinoma and tamoxifen: clearing up a controversy [letter]. Clin Cancer Res 1996 Jan;2(1):223-4. Comment on: Clin Cancer Res 1995 May;1(5):467-72. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9816110&dopt;=Abstract

Andersson M, Storm HH, Mouridsen HT. Incidence of new primary cancers after adjuvant tamoxifen therapy and radiotherapy for early breast cancer. J Natl Cancer Inst 1991;83(14):1013-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=2072407&dopt;=Abstract

Anker G, Lonning PE, Ueland PM, Refsum H, Lien EA. Plasma levels of the atherogenic amino acid homocysteine in post-menopausal women with breast cancer treated with tamoxifen. Int J Cancer 1995 Jan 27;60(3):365-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7829246&dopt;=Abstract

Anker GB, Lonning PE, Aakvaag A, Lien EA. Thyroid function in postmenopausal breast cancer patients treated with tamoxifen. Scand J Clin Lab Invest 1998 Apr;58(2):103-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9587161&dopt;=Abstract

Ascher SM, Imaoka I, Lage JM. Tamoxifen-induced uterine abnormalities: the role of imaging. Radiology 2000 Jan;214(1):29-38. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10644098&dopt;=Abstract

Ascher SM, Johnson JC, Barnes WA, Bae CJ, Patt RH, Zeman RK. MR imaging appearance of the uterus in postmenopausal women receiving tamoxifen therapy for breast cancer: histopathologic correlation. Radiology 1996 Jul;200(1):105-10. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8657895&dopt;=Abstract

Assikis VJ, Jordan VC. Risks and benefits of tamoxifen therapy. Oncology (Huntingt) 1997 Feb;11(2 Suppl 1):21-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9065923&dopt;=Abstract

Ayoub JP, Valero V, Hortobagyi GN. Tamoxifen-induced female androgenetic alopecia in a patient with breast cancer [letter]. Ann Intern Med 1997 May 1;126(9):745-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9139575&dopt;=Abstract

Barakat RR. The effect of tamoxifen on the endometrium. Oncology (Huntingt) 1995 Feb;9(2):129-34; discussion 139-40, 142. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8771096&dopt;=Abstract

Barakat RR, Adhikari D, Federici M, Saigo PE, Bertino JR, Banerjee D. Evaluation of p53, bcl-2 and c-ki-ras status in endometrial cancers occurring after breast cancer with or without tamoxifen treatment [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A1289.

Barakat RR, Gilewski TA, Almadrones L, Saigo PE, Venkatraman E, Hoskins WJ. The effect of adjuvant tamoxifen (t) on the endometrium in women with breast cancer: a prospective study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A1381.

Barakat RR, Gilewski TA, Almadrones L, Saigo PE, Venkatraman E, Hoskins WJ. The effect of adjuvant tamoxifen (T) on the endometrium in women with breast cancer: a prospective study. Gynecol Oncol 1999;72(3):466-7.

Barakat RR, Gilewski TA, Saigo PE, Almadrones L, Tyson P, Norton L, Hoskins WJ. The effect of adjuvant tamoxifen on the endometrium in women with breast cancer: an interim analysis of a prospective study [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A778.

Barisic D, Ilic J, Babic D, Grizelj V. Endometrial carcinoma in two patients on adjuvant tamoxifen treatment for breast cancer. Croat Med J 1996;37(1):51-3.

Barni S, Ardizzoia A. Tamoxifen-induced sexual dysfunction in a breast cancer patient: a case report. Tumori 1998 May-Jun;84(3):417-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9678629&dopt;=Abstract

Barni S, Lissoni P, Tancini G, Ardizzoia A, Cazzaniga M. Effects of one-year adjuvant treatment with tamoxifen on bone mineral density in postmenopausal breast cancer women. Tumori 1996 Jan-Feb;82(1):65-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8623509&dopt;=Abstract

Baum M, Cuzick J. Adjuvant treatment with tamoxifen. Side effects may have been overstated [letter]. BMJ 1996 Apr 20;312(7037):1036. Comment on: BMJ 1996 Feb 17;312(7028):389-90. Comment in: BMJ 1996 Aug 24;313(7055):493-4; BMJ 1996 Dec 7;313(7070):1484. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8616357&dopt;=Abstract

Beitler JJ. Tamoxifen and sexuality: Let's listen to the data speak [letter]. J Clin Oncol 1999 Nov;17(11):3689-90. Comment on: J Clin Oncol 1999 May;17(5):1488-92. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10550170&dopt;=Abstract

Bentzen SM, Skoczylas JZ, Overgaard M, Overgaard J. Radiotherapy-related lung fibrosis enhanced by tamoxifen. J Natl Cancer Inst 1996 Jul 3;88(13):918-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8656444&dopt;=Abstract

Bergman L, Beelen ML, Gallee MP, Benraadt J, Leeuwen FE va. The effect of tamoxifen on the risk and prognosis of endometrial cancer following breast cancer: a study with 309 cases [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A1366.

Bergman L, Benraadt J, van Leeuwen FE. Tamoxifen, balancing risks and benefits. Neth J Med 1996 Dec;49(6):228-34. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8990861&dopt;=Abstract

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Bernhard J, Castiglione-Gertsch M, Hurny C, Schmitz SF Hs, Goldhirsch A, Cavalli F, Fey M, Morant R, Bonnefoi H, Forrer P, Thurlimann B. Quality of life in postmenopausal patients with breast cancer after failure of tamoxifen: comparing patients with response versus patients with no change for at least 6 months under second-line hormonal treatment (sakk 20/90) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A492.

Bernhard J, Castiglione-Gertsch M, Schmitz SF, Thurlimann B, Cavalli F, Morant R, Fey MF, Bonnefoi H, Goldhirsch A, Hurny C. Quality of life in postmenopausal patients with breast cancer after failure of tamoxifen: formestane versus megestrol acetate as second-line hormonal treatment. Swiss Group for Clinical Cancer Research (SAKK). Eur J Cancer 1999 Jun;35(6):913-20. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10533471&dopt;=Abstract

Bernhard J, Thurlimann B, Schmitz SF, Castiglione-Gertsch M, Cavalli F, Morant R, Fey MF, Bonnefoi H, Goldhirsch A, Hurny C. Defining clinical benefit in postmenopausal patients with breast cancer under second-line endocrine treatment: does quality of life matter? J Clin Oncol 1999 Jun;17(6):1672-9. Comment in: J Clin Oncol 1999 Jun;17(6):1651-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10561203&dopt;=Abstract

Bernstein L, Deapen D, Cerhan JR, Schwartz SM, Liff J, McGann-Maloney E, Perlman JA, Ford L. Tamoxifen therapy for breast cancer and endometrial cancer risk. J Natl Cancer Inst 1999 Oct 6;91(19):1654-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10511593&dopt;=Abstract

Bertolissi A, Cartei G, Turrin D, Cioschi B, Rizzi V. Behaviour of vaginal epithelial maturation and sex hormone binding globulin in post-menopausal breast cancer patients during the first year of tamoxifen therapy. Cytopathology 1998 Aug;9(4):263-70. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9710696&dopt;=Abstract

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Borner MM, Bacchi M, Castiglione M. Possible deleterious effect of tamoxifen in premenopausal women with locoregional recurrence of breast cancer. Eur J Cancer 1996 Nov;32A(12):2173-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9014762&dopt;=Abstract

Bostrom A, Sjolin-Forsberg G, Wilking N, Bergh J. Radiation recall--another call with tamoxifen. Acta Oncol 1999;38(7):955-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10606426&dopt;=Abstract

Browne VW, Buzdar AU, Smith TL, McNeese M, Strom E, Dye C, Hortobagyi GN. The incidence of second primary breast cancer (spbc) in women treated with chemotherapy alone versus women treated with doxorubicin-containing chemotherapy (fac) and radiotherapy (xrt) [abstract]. Breast Cancer Res Treat 1996;37 Suppl:36.

Buzdar A, Hortobagyi G, Kau S, Holmes F, Fraschini G, Theriault R, Singletary S. Long-term efficacy and toxicities of doxorubicin-containing adjuvant therapy in breast cancer--md anderson cancer center studies [abstract]. Paper presented at: 4th International Congress on Anti-Cancer Chemotherapy; 1993 Feb 2-5; Paris.

Cameron LD, Leventhal H, Love RR. Trait anxiety, symptom perceptions, and illness-related responses among women with breast cancer in remission during a tamoxifen clinical trial. Health Psychol 1998 Sep;17(5):459-69. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9776005&dopt;=Abstract

Carcangiu ML. Uterine pathology in tamoxifen-treated patients with breast cancer. Anat Pathol 1997;2:53-70. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9575370&dopt;=Abstract

Carcangiu ML, Gal D, Weiselberg L, Fisher ER, Fisher B, Wickerham DL, Costantino JP, Redmond C. Re: Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14 (3). J Natl Cancer Inst 1994;86(16):1251-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8040895&dopt;=Abstract

Cardoso FF/Juacaba SF, Menezes DB, Tavares RA, Vasconcelos PM, Proenca AR, Landim RM, Veras IM, Ribeiro RA. Clinical, ultrasonographic, hysteroscopic, and histopathological evaluation of the endometrial changes in women with breast cancer (BC) submitted to adjuvant tamoxifen (TMX) [abstract]. Eur J Cancer 1999;35 Suppl 4:S376.

Caton J, Ellis R. Comparison of tamoxifen side effects in men and women with breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A215.

Cecchini S, Ciatto S, Bonardi R, Mazzotta A, Grazzini G, Pacini P, Muraca MG. Screening by ultrasonography for endometrial carcinoma in postmenopausal breast cancer patients under adjuvant tamoxifen. Gynecol Oncol 1996 Mar;60(3):409-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8774648&dopt;=Abstract

Cecchini S, Ciatto S, Bonardi R, Mazzotta A, Pacini P, Muraca MG, Zappa M. Risk of endometrial cancer in breast cancer patients under long-term adjuvant treatment with tamoxifen. Tumori 1998 Jan-Feb;84(1):21-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9619708&dopt;=Abstract

Ceci O, Bettocchi S, Marello F, Nappi L, Chiechi LM, Laricchia L, Masciandaro A. Sonographic, hysteroscopic, and histologic evaluation of the endometrium in postmenopausal women with breast cancer receiving tamoxifen. J Am Assoc Gynecol Laparosc 2000 Feb;7(1):77-81. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10648743&dopt;=Abstract

Chap L, Shpiner R, Levine M, Norton L, Lill M, Glaspy J. Early diagnosis of pulmonary toxicity from conditioning chemotherapy for breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A984.

Chap L, Shpiner R, Levine M, Norton L, Lill M, Glaspy J. Pulmonary toxicity of high-dose chemotherapy for breast cancer: A non-invasive approach to diagnosis and treatment. Bone Marrow Transplant 1997 Dec 10;20(12):1063-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9466279&dopt;=Abstract

Cheng WF, Lin HH, Torng PL, Huang SC. Comparison of endometrial changes among symptomatic tamoxifen-treated and nontreated premenopausal and postmenopausal breast cancer patients. Gynecol Oncol 1997 Aug;66(2):233-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9264568&dopt;=Abstract

Clear thinking on tamoxifen. Johns Hopkins Med Lett Health After 50 1998 Jul;10(5):1-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9650523&dopt;=Abstract

Cobelli S, Dambrosio M, Farina G, Rovej R, Tomirotti M, Scanni A. Long-term toxicity in adjuvant treatment with tamoxifen. J Chemother 1997 Aug;9(4):300-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9269612&dopt;=Abstract

Cohen I, Altaras MM, Beyth Y, Zalel Y, Shapira J, Yigael D, Tepper R. Ovarian volume in postmenopausal breast cancer patients treated with tamoxifen. Gynecol Oncol 1997 Jan;64(1):105-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8995556&dopt;=Abstract

Cohen I, Altaras MM, Shapira J, Tepper R, Cordoba M, Figer A, Zalel Y, Dror Y, Beyth Y. Different coexisting endometrial histological features in asymptomatic postmenopausal breast cancer patients treated with tamoxifen. Gynecol Obstet Invest 1997;43(1):60-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9015703&dopt;=Abstract

Cohen I, Azaria R, Fishman A, Tepper R, Shapira J, Beyth Y. Endometrial cancers in postmenopausal breast cancer patients with tamoxifen treatment. Int J Gynecol Pathol 1999 Oct;18(4):304-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10542937&dopt;=Abstract

Cohen I, Bernheim J, Azaria R, Tepper R, Sharony R, Beyth Y. Malignant endometrial polyps in postmenopausal breast cancer tamoxifen-treated patients. Gynecol Oncol 1999 Oct;75(1):136-41. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10502440&dopt;=Abstract

Cohen I, Bernheim J, Fishman A, Shapira J, Tepper R, Beyth Y, Cordoba M, Yigael D, Altaras MM. Estrogen and progesterone receptors in benign ovarian tumors of menopausal breast cancer patients treated with tamoxifen. Gynecol Obstet Invest 1998 Aug;46(2):116-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9701692&dopt;=Abstract

Cohen I, Beyth Y, Bernheim J, Shapira J, Cordoba M, Aviram R, Figer A, Yigael D, Altaras MM. Different coexisting gynecological and endometrial pathologies in postmenopausal breast cancer patients treated with tamoxifen. Gynecol Obstet Invest 1998 Aug;46(2):123-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9701693&dopt;=Abstract

Cohen I, Beyth Y, Shapira J, Tepper R, Fishman A, Cordoba M, Bernheim J, Yigael D, Altaras MM. High frequency of adenomyosis in postmenopausal breast cancer patients treated with tamoxifen. Gynecol Obstet Invest 1997;44(3):200-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9359649&dopt;=Abstract

Cohen I, Beyth Y, Tepper R, Figer A, Shapira J, Cordoba M, Yigael D, Altaras MM. Adenomyosis in postmenopausal breast cancer patients treated with tamoxifen: a new entity? Gynecol Oncol 1995 Jul;58(1):86-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7789896&dopt;=Abstract

Cohen I, Beyth Y, Tepper R, Shapira J, Zalel Y, Figer A, Cordoba M, Yigael D, Altaras MM. Ovarian tumors in postmenopausal breast cancer patients treated with tamoxifen. Gynecol Oncol 1996 Jan;60(1):54-8. Comment in: Gynecol Oncol 1996 Apr;61(1):158-60. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8557228&dopt;=Abstract

Cohen I, Figer A, Altaras MM, Tepper R, Shapira J, Cordoba M, Yigael D, Arbel Y, Beyth Y. Common endometrial decidual reaction in postmenopausal breast cancer patients treated with tamoxifen and progestogens. Int J Gynecol Pathol 1996 Jan;15(1):17-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8852441&dopt;=Abstract

Cohen I, Figer A, Tepper R, Shapira J, Altaras MM, Yigael D, Beyth Y. Ovarian overstimulation and cystic formation in premenopausal tamoxifen exposure: comparison between tamoxifen-treated and nontreated breast cancer patients. Gynecol Oncol 1999 Feb;72(2):202-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10021302&dopt;=Abstract

Cohen I, Perel E, Flex D, Tepper R, Altaras MM, Cordoba M, Beyth Y. Endometrial pathology in postmenopausal tamoxifen treatment: comparison between gynaecologically symptomatic and asymptomatic breast cancer patients. J Clin Pathol 1999 Apr;52(4):278-82. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10474520&dopt;=Abstract

Cohen I, Perel E, Tepper R, Flex D, Figer A, Shapira J, Altaras MM, Fishman A, Bernheim J, Cordoba M, Yigael D, Beyth Y. Dose-dependent effect of tamoxifen therapy on endometrial pathologies in postmenopausal breast cancer patients. Breast Cancer Res Treat 1999 Feb;53(3):255-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10369071&dopt;=Abstract

Colls BM, George PM. Severe hypertriglyceridaemia and hypercholesterolaemia associated with tamoxifen use. Clin Oncol (R Coll Radiol) 1998;10(4):270-1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9764383&dopt;=Abstract

Cook LS, Weiss NS, Potts MS. Second cancers after adjuvant tamoxifen therapy for breast cancer [letter]. J Natl Cancer Inst 1997 May 7;89(9):657-9. Comment on: J Natl Cancer Inst 1996 Jun 19;88(12):832-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9150192&dopt;=Abstract

Cook LS, Weiss NS, Schwartz SM, White E, McKnight B, Moore DE, Daling JR. Population-based study of tamoxifen therapy and subsequent ovarian, endometrial, and breast cancers. J Natl Cancer Inst 1995 Sep 20;87(18):1359-64. Comment in: J Natl Cancer Inst 1995 Sep 20;87(18):1343-5; J Natl Cancer Inst 1996 Feb 21;88(3-4):210-1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7658496&dopt;=Abstract

Costantino JP, Kuller LH, Ives DG, Fisher B, Dignam J. Coronary heart disease mortality and adjuvant tamoxifen therapy. J Natl Cancer Inst 1997 Jun 4;89(11):776-82. Comment in: J Natl Cancer Inst 1997 Jun 4;89(11):747-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9182975&dopt;=Abstract

Cuenca RE, Giachino J, Arredondo MA, Hempling R, Edge SB. Endometrial carcinoma associated with breast carcinoma: low incidence with tamoxifen use. Cancer 1996 May 15;77(10):2058-63. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8640670&dopt;=Abstract

Curtis RE, Boice JD Jr, Shriner DA, Hankey BF, Fraumeni JF Jr. Second cancers after adjuvant tamoxifen therapy for breast cancer. J Natl Cancer Inst 1996 Jun 19;88(12):832-4. Comment in: J Natl Cancer Inst 1996 Oct 16;88(20):1496-7; discussion 1497-9; J Natl Cancer Inst 1996 Oct 16;88(20):1497-9; J Natl Cancer Inst 1997 May 7;89(9):657-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8637050&dopt;=Abstract

Cuzick J, Allen D, Baum M, Barrett J, Clark G, Kakkar V, Melissari E, Moniz C, Moore J, Parsons V, et al. Long term effects of tamoxifen. Biological effects of Tamoxifen Working Party. Eur J Cancer 1992;29A(1):15-21. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1445735&dopt;=Abstract

Davidson NE. Tamoxifen - Panacea or Pandora's box? New Engl J Med 1992;326(13):885-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1542327&dopt;=Abstract

Day R, Ganz P, Costantino J, Wickerham D, Cronin W. Health-related quality of life (HRQL) and tamoxifen in breast cancer prevention [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A2284.

Day R, Ganz PA, Costantino JP, Cronin WM, Wickerham DL, Fisher B. Health-related quality of life and tamoxifen in breast cancer prevention: a report from the national surgical adjuvant breast and bowel project p-1 study. J Clin Oncol 1999;17(9):2659-69. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10561339&dopt;=Abstract

de Vries EG, Mourits MJ, ten Hoor KA, Hollema H, Sluiter WJ, de Bruijn HW, van der Zee AG, Willemse PH. Ovarian cysts in women receiving tamoxifen in a randomized adjuvant breast cancer study +/- high-dose chemotherapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A580.

Decensi A, Fontana V, Bruno S, Gustavino C, Gatteschi B, Costa A. Effect of tamoxifen on endometrial proliferation. J Clin Oncol 1996;14(2):434-40. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8636754&dopt;=Abstract

Deshmukh N, Tripathi SP. Thrombosis of tibial arteries in a patient receiving tamoxifen therapy. Cancer 1995;76(6):1006-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8625201&dopt;=Abstract

Dew JE, Eden JA. Gynaecological complications of women treated with tamoxifen for breast cancer. Aust N Z J Obstet Gynaecol 1995 May;35(2):198-200. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7677689&dopt;=Abstract

Dignam JJ, Bryant J, Wieand HS, Fisher B, Wolmark N. Early stopping of a clinical trial when there is evidence of no treatment benefit: protocol B-14 of the National Surgical Adjuvant Breast and Bowel Project. Control Clin Trials 1998 Dec;19(6):575-88. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9875837&dopt;=Abstract

Dignam JJ, Fisher B. Occurrence of stroke with tamoxifen in NSABP B-24 [letter]. Lancet 2000 Mar 4;355(9206):848-9. Comment on: Lancet 1999 Jun 12;353(9169):1993-2000. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10711957&dopt;=Abstract

El-Masry A, Nooman MF, Ibrahim I, El-Gawad SA. Bone density changes in postmenopausal women with breast cancer treated with long term adjuvant tamoxifen. J Med Res Inst 1997;18(1):170-8.

Engan T, Krane J, Johannessen DC, Lonning PE, Kvinnsland S. Changes in plasma of breast cancer patients during treatment with tamoxifen and aromatase inhibitor as evaluated by lipid measurements and nuclear magnetic resonance (nmr) spectroscopy [abstract]. Anticancer Res 1995;15(5A):1694-5.

Esteller M, Garcia A, Martinez-Palones JM, Xercavins J, Reventos J. Endometrial carcinoma in tamoxifen-treated breast cancer patient: clinicopathological, immunohistochemical, and genetic analysis. Int J Gynecol Pathol 1999 Oct;18(4):387-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10542949&dopt;=Abstract

Exacoustos C, Zupi E, Cangi B, Chiaretti M, Arduini D, Romanini C. Endometrial evaluation in postmenopausal breast cancer patients receiving tamoxifen: an ultrasound, color flow Doppler, hysteroscopic and histological study. Ultrasound Obstet Gynecol 1995 Dec;6(6):435-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8903921&dopt;=Abstract

Farina G, Mantica C, La Verde N, Vimercati C, Galassi B, Cobelli S, Tomirotti M, Scanni A. Toxicity of long-term adjuvant treatment with tamoxifen (tam) in breast cancer (bc) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A257.

Fisher B. Commentary on endometrial cancer deaths in tamoxifen-treated breast cancer patients. J Clin Oncol 1996;14(3):1027-39. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8622007&dopt;=Abstract

Fisher B, Costantino JP, Redmond CK, Fisher ER, Wickerham DL, Cronin WM. Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the national surgical adjuvant breast and bowel project (nsabp) b-14. J Natl Cancer Inst 1994;86(7):527-37. Comment in: J Natl Cancer Inst 1994 Apr 6;86(7):478-9; J Natl Cancer Inst 1994 Jul 6;86(13):1025-6; J Natl Cancer Inst 1994 Aug 17;86(16):1251-2; discussion 1253-5; J Natl Cancer Inst 1994 Aug 17;86(16):1252-3; discussion 1255. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8133536&dopt;=Abstract

Floren LC, Hebert MF, Venook AP, Jordan VC, Cisneros A, Somberg KA. Tamoxifen in liver disease: potential exacerbation of hepatic dysfunction. Ann Oncol 1998 Oct;9(10):1123-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9834826&dopt;=Abstract

Folk JJ, Mazur MT, Eddy GL, Musa AG. Secretory endometrial adenocarcinoma in a patient on tamoxifen for breast cancer: a report of a case. Gynecol Oncol 1995 Jul;58(1):133-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7789881&dopt;=Abstract

Fotiou S, Tserkezoglou A, Hadjieleftheriou G, Apostolikas N, Karydas I, Stravolemos K. Tamoxifen associated uterine pathology in breast cancer patients with abnormal bleeding. Anticancer Res 1998 Jan-Feb;18(1B):625-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9584044&dopt;=Abstract

Fowble B, Fein DA, Hanlon AL, Eisenberg BL, Hoffman JP, Sigurdson ER, Daly MB, Goldstein LJ. The impact of tamoxifen on breast recurrence, cosmesis, complications, and survival in estrogen receptor-positive early-stage breast cancer. Int J Radiat Oncol Biol Phys 1996 Jul 1;35(4):669-77. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8690632&dopt;=Abstract

Fujikawa T, Nishimura S, Matsusue S, Takeda H. Abnormal vaginal bleeding from endometrial polyps in a woman receiving tamoxifen therapy for breast cancer: report of a case. Surg Today 1997;27(8):769-72. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9306597&dopt;=Abstract

Ganz PA, Day R, Costantino J. Compliance with quality of life data collection in the National Surgical Adjuvant Breast and Bowel Project (NSABP) Breast Cancer Prevention Trial. Stat Med 1998 Apr 15;17(5-7):613-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9549810&dopt;=Abstract

Ganz PA, Day R, Ware JE Jr, Redmond C, Fisher B. Base-line quality-of-life assessment in the national surgical adjuvant breast and bowel project breast cancer prevention trial. J Natl Cancer Inst 1995;87(18):1372-82. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7658498&dopt;=Abstract

Gerson R, Altamirano E, Cruz H, Cal y Mayor M, Sandoval F, Miranda H, Sanchez-Forgach E. Endometrial changes (ec) in patients (pts) with breast cancer (bc) treated with tamoxifen (t) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A226.

Gill BL, Simpson JF, Somlo G, McGonigle KF, Wilczynski SP. Effects of tamoxifen on the cytology of the uterine cervix in breast cancer patients. Diagn Cytopathol 1998 Dec;19(6):417-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9839130&dopt;=Abstract

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Gorin MB, Day R, Costantino JP, Fisher B, Redmond CK, Wickerham L, Gomolin JE, Margolese RG, Mathen MK, Bowman DM, Kaufman DI, Dimitrov NV, Singerman LJ, Bornstein R, Wolmark N, Kaufmann D/[corrected to Kaufman DI]. Long-term tamoxifen citrate use and potential ocular toxicity . Am J Ophthalmol 1998 Apr;125(4):493-501. Published erratum appears in Am J Ophthalmol 1998 Aug;126(2):338. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9559735&dopt;=Abstract

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Marttunen MB, Hietanen P, Tiitinen A, Ylikorkala O. Comparison of effects of tamoxifen and toremifene on bone biochemistry and bone mineral density in postmenopausal breast cancer patients. J Clin Endocrinol Metab 1998 Apr;83(4):1158-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9543133&dopt;=Abstract

Marttunen MB, Hietanen P, Titinen A, Roth HJ, Viinikka L, Ylikorkala O. Effects of tamoxifen and toremifene on urinary excretion of pyridinoline and deoxypyridinoline and bone density in postmenopausal patients with breast cancer. Calcif Tissue Int 1999 Nov;65(5):365-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10541761&dopt;=Abstract

Maruyama S, Hirayama C, Abe J, Tanaka J, Matsui K. Chronic active hepatitis and liver cirrhosis in association with combined tamoxifen/tegafur adjuvant therapy. Dig Dis Sci 1995 Dec;40(12):2602-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8536519&dopt;=Abstract

Mastroianni A, Bellati CE, Facchetti G, Oldani S, Franzini C, Berrino F. Increased plasma HDL cholesterol and apo-A1 in breast cancer patients during adjuvant tamoxifen therapy [abstract]. Clin Chem Lab Med 1999;37 Suppl:S267.

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Pandya KJ, Raubertas RF, Flynn PJ, Hynes HE, Rosenbluth RJ, Kirshner JJ, Pierce HI, Dragalin V, Morrow GR. Oral clonidine in postmenopausal patients with breast cancer experiencing tamoxifen-induced hot flashes: a University of Rochester Cancer Center Community Clinical Oncology Program study. Ann Intern Med 2000 May 16;132(10):788-93. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10819701&dopt;=Abstract

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Pizzichetta MA, Giuliotto N, Zottar M, Crivellari D, Foladore S, Veronesi A. Tamoxifen (tam) as adjuvant after surgery for breast cancer (bc) and tamoxifen or placebo (tam/plac) as chemoprevention (cp) in healthy women: different compliance to treatment [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A343.

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Ragaz J. Interaction of tamoxifen's impact on overall net mortality and quality of life. Oncology (Huntingt) 1997 Feb;11(2 Suppl 1):45-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9065927&dopt;=Abstract

Ragaz J, Alsaleh E, Hoskins P, Beratsova S, Benedet L, Miller D, Coldman A, Hislop G. Characteristics of uterine and ovarian cancer (ut, ov ca) in patients with prior breast cancer (brca) versus general population - impact of tamoxifen (tam). Analysis of the british columbia cancer agency (bcca) data [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A1526.

Ragaz J, Coldman A. Survival impact of adjuvant tamoxifen on competing causes of mortality in breast cancer survivors, with analysis of mortality from contralateral breast cancer, cardiovascular events, endometrial cancer, and thromboembolic episodes. J Clin Oncol 1998 Jun;16(6):2018-24. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9626198&dopt;=Abstract

Ray A, Leonard RC. Side effects of tamoxifen are distressing and common [letter]. BMJ 1996 Dec 7;313(7070):1484. Comment on: BMJ 1996 Apr 20;312(7037):1036; BMJ 1996 Aug 24;313(7055):493-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8973261&dopt;=Abstract

Reichman BS. Tamoxifen's impact on the management of breast cancer: patient perspectives. Oncology (Huntingt) 1997 Feb;11(2 Suppl 1):55-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9065929&dopt;=Abstract

Resch A, Biber E, Seifert M, Resch H. Evidence that tamoxifen preserves bone density in late postmenopausal women with breast cancer. Acta Oncol 1998;37(7-8):661-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10050983&dopt;=Abstract

Robinson DC, Bloss JD, Schiano MA. A retrospective study of tamoxifen and endometrial cancer in breast cancer patients. Gynecol Oncol 1995 Nov;59(2):186-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7590470&dopt;=Abstract

Robinson E, Kimmick GG, Muss HB. Tamoxifen in postmenopausal women a safety perspective. Drugs Aging 1996 May;8(5):329-37. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8935395&dopt;=Abstract

Rutqvist LE. Re: second cancers after adjuvant tamoxifen therapy for breast cancer [letter]. J Natl Cancer Inst 1996 Oct 16;88(20):1497-9; discussion, 1497-9. Comment on: J Natl Cancer Inst 1996 Jun 19;88(12):832-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8841030&dopt;=Abstract

Rutqvist LE, Johansson H, Signomklao T, Johansson U, Fornander T, Wilking N. Adjuvant tamoxifen therapy for early stage breast cancer and second primary malignancies. Stockholm Breast Cancer Study Group. J Natl Cancer Inst 1995 May 3;87(9):645-51. Comment in: J Natl Cancer Inst 1995 May 3;87(9):623-6; J Natl Cancer Inst 1995 May 3;87(9):627-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7752269&dopt;=Abstract

Sasco AJ. Tamoxifen and menopausal status: risks and benefits [letter]. Lancet 1996 Mar 16;347(9003):761. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8602018&dopt;=Abstract

Sasco AJ, Raffi F, Satge D, Goburdhun J, Fallouh B, Leduc B. Endometrial mullerian carcinosarcoma after cessation of tamoxifen therapy for breast cancer. Int J Gynaecol Obstet 1995 Mar;48(3):307-10. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7781875&dopt;=Abstract

Schlesinger C, Kamoi S, Ascher SM, Kendell M, Lage JM, Silverberg SG. Endometrial polyps: a comparison study of patients receiving tamoxifen with two control groups. Int J Gynecol Pathol 1998 Oct;17(4):302-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9785130&dopt;=Abstract

Sedlacek SM. Estrogen withdrawal symptoms after discontinuation of long term adjuvant (ADJ) tamoxifen (TAM) in women with breast cancer [abstract]. Breast Cancer Res Treat 1997;46(1):31.

Seoud M, Salem Z, Shamseddine A, Khabbaz A, Zaatari G, Khalil A. Papillary serous carcinoma of the ovary following prolonged tamoxifen treatment. Eur J Gynaecol Oncol 1999;20(3):237-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10410898&dopt;=Abstract

Shariff S, Cumming CE, Lees A, Handman M, Cumming DC. Mood disorder in women with early breast cancer taking tamoxifen, an estradiol receptor antagonist. An expected or unexpected effect? Ann N Y Acad Sci 1995 Jun 12;761:365-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7625737&dopt;=Abstract

Shulman A, Cohen I, Maymon R, Altaras MM. Tamoxifen treatment and its consequences [letter]. Hum Reprod 1995 Aug;10(8):2174-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8567864&dopt;=Abstract

Shushan A, Peretz T, Mor-Yosef S. Therapeutic approach to ovarian cysts in tamoxifen-treated women with breast cancer. Int J Gynaecol Obstet 1996 Mar;52(3):249-53. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8775677&dopt;=Abstract

Shushan A, Peretz T, Uziely B, Lewin A, Mor-Yosef S. Ovarian cysts in premenopausal and postmenopausal tamoxifen-treated women with breast cancer. Am J Obstet Gynecol 1996 Jan;174(1 Pt 1):141-4. Comment in: Am J Obstet Gynecol 1996 Sep;175(3 Pt 1):752-3. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8571997&dopt;=Abstract

Silva EG, Tornos C, Malpica A, Mitchell MF. Uterine neoplasms in patients treated with tamoxifen. J Cell Biochem Suppl 1995;23:179-83. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8747394&dopt;=Abstract

Sivalingam N, Pathmalingam A. The role of endovaginal ultrasonography and the value of endometrial biopsy in breast cancer patients on tamoxifen therapy. Singapore Med J 1999 Jun;40(6):402-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10489508&dopt;=Abstract

Son EJ, Oh KK, Kim EK, Son HJ, Jung WH, Lee HD. Leiomyoma of the breast in a 50-year-old woman receiving tamoxifen. AJR Am J Roentgenol 1998 Dec;171(6):1684-6. Comment in: AJR Am J Roentgenol 1998 Dec;171(6):1451. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9843313&dopt;=Abstract

Son HJ, Oh KK. Significance of follow-up mammography in estimating the effect of tamoxifen in breast cancer patients who have undergone surgery. AJR Am J Roentgenol 1999 Oct;173(4):905-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10511146&dopt;=Abstract

Surbek DV, Hoesli I, Torhorst J, Almendral AC, Dellas A, Holzgreve W. Virilizing ovarian tumor of low malignant potential associated with antecedent tamoxifen use for breast cancer. Gynecol Oncol 1998 Mar;68(3):293-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9570983&dopt;=Abstract

Takai N, Fukuda J, Yoshimatsu J, Miyakawa I. Homologous carcinosarcoma of the uterine corpus associated with tamoxifen therapy. Int J Clin Oncol 2000;5(2):140-3.

Tang R, Shields J, Schiffman J, Li H, Locher D, Hampton J, Prager T, Pardo G. Retinal changes associated with tamoxifen treatment for breast cancer. Eye 1997;11(Pt 3):295-7. Comment in: Eye 1998;12 (Pt 3a):485-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9373465&dopt;=Abstract

Taylor WS, Anderson A, Lessin L, Goldstein P. Transvaginal sonography (tvs) reveals endometrial (endo) abnormalities in breast cancer patients (pts) taking tamoxifen (tam): a preliminary report [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A949.

Tepper R, Beyth Y, Altaras MM, Zalel Y, Shapira J, Cordoba M, Cohen I. Value of sonohysterography in asymptomatic postmenopausal tamoxifen-treated patients. Gynecol Oncol 1997 Mar;64(3):386-91. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9062139&dopt;=Abstract

Tesoro MR, Borgida AF, MacLaurin NA, Asuncion CM. Transvaginal endometrial sonography in postmenopausal women taking tamoxifen. Obstet Gynecol 1999;93(3):363-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10074980&dopt;=Abstract

Thangaraju M, Ezhilarasi R, Sachdanandam P. Effect of tamoxifen on erythrocyte membrane lipids, lipid peroxides, and antioxidative enzymes in breast cancer women. Cancer Biochem Biophys 1995 Jan;14(4):297-302. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7767903&dopt;=Abstract

Thangaraju M, Rameshbabu J, Vasavi H, Ilanchezhian S, Vinitha R, Sachdanandam P. The salubrious effect of tamoxifen [correction of Tamaxifen] on serum marker enzymes, glycoproteins, and lysosomal enzymes level in breast cancer woman. Mol Cell Biochem 1998 Aug;185(1-2):85-94. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9746215&dopt;=Abstract

Thompson DS, Spanier CA, Vogel VG. The relationship between tamoxifen, estrogen, and depressive symptoms. Breast J 1999;5(6):375-82.

Tomas E, Kauppila A, Blanco G, Apaja-Sarkkinen M, Laatikainen T. Comparison between the effects of tamoxifen and toremifene on the uterus in postmenopausal breast cancer patients. Gynecol Oncol 1995 Nov;59(2):261-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7590484&dopt;=Abstract

Treilleux T, Mignotte H, Clement-Chassagne C, Guastalla P, Bailly C. Tamoxifen and malignant epithelial-nonepithelial tumours of the endometrium: report of six cases and review of the literature. Eur J Surg Oncol 1999 Oct;25(5):477-82. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10527595&dopt;=Abstract

Ursin G, Pike MC, Spicer DV, Porrath SA, Reitherman RW. Can mammographic densities predict effects of tamoxifen on the breast? [letter]. J Natl Cancer Inst 1996 Jan 17;88(2):128-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8537975&dopt;=Abstract

van der Pompe G, Antoni MH, Visser A, Heijnen CJ. Effect of mild acute stress on immune cell distribution and natural killer cell activity in breast cancer patients. Biol Psychol 1998 May;48(1):21-36. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9676357&dopt;=Abstract

Veronesi A, Pizzichetta MA, Ferlante MA, Zottar M, Magri MD, Crivellari D, Foladore S. Tamoxifen as adjuvant after surgery for breast cancer and tamoxifen or placebo as chemoprevention in healthy women: different compliance with treatment. Tumori 1998 May-Jun;84(3):372-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9678620&dopt;=Abstract

Vrbanec D, Reiner Z, Belev B, Plestina S. Changes in serum lipid and lipoprotein levels in postmenopausal patients with node-positive breast cancer treated with tamoxifen. Tumori 1998 Nov-Dec;84(6):687-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10080678&dopt;=Abstract

Vrscaj MU, Bebar S, Djurisic A, Fras PA. Endometrial cancer after tamoxifen treatment of breast cancer. Results of a retrospective cohort study. Eur J Gynaecol Oncol 1999;20(1):20-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10422675&dopt;=Abstract

Wasan KM, Ramaswamy M, Haley J, Dunn BP. Administration of long-term tamoxifen therapy modifies the plasma lipoprotein-lipid concentration and lipid transfer protein I activity in postmenopausal women with breast cancer. J Pharm Sci 1997 Jul;86(7):876-9. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9232532&dopt;=Abstract

Willen R, Lindahl B, Andolf E, Ingvar C, Liedman R, Ranstam J. Histopathologic findings in thickened endometria, as measured by ultrasound in asymptomatic, postmenopausal breast cancer patients on various adjuvant treatment including tamoxifen. Anticancer Res 1998 Jan-Feb;18(1B):667-76. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9584050&dopt;=Abstract

Yalcin S, Gollu I, Demiroglu H, Tekuzman G. Acute leukaemia during tamoxifen therapy. Med Oncol 1997;14(1):61-2. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9232614&dopt;=Abstract

Yao JC, Thomakos N, McLaughlin P, Buchholz TA, Kudelka AP. Tamoxifen-induced thrombocytopenia. Am J Clin Oncol 1999 Oct;22(5):529-32. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10521073&dopt;=Abstract

Yu KM, Chan KS, Tang LC. Gynaecological complications in tamoxifen-treated breast cancer patients. Hong Kong Pract 1998;20(2):82-6.

Zarbo G, Caruso G, Zammitti M, Caruso S, Zarbo R. The effects of tamoxifen therapy on the endometrium. Eur J Gynaecol Oncol 2000;21(1):86-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10726629&dopt;=Abstract

Zaza M, Antimi M, Grassi G, Di Felice M, Minelli M, Calugi A. The role of colposcopy in evaluating the tamoxifen-dependent estrogen effects in post-menopause patients in treatment for ER+ breast cancer. Ital J Gynaecol Obstet 1995;7(1):1-5.

Zidan J, Rubenstein W. Effect of adjuvant tamoxifen therapy on thyroid function in postmenopausal women with breast cancer. Oncology 1999;56(1):43-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9885376&dopt;=Abstract

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### 6c. Chemotherapy

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Abbott B, Rivera E, Rosales M, Michaud L, Hortobagyi G. Weight-based heparin compared to current standard of care heparin dosing in breast cancer patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A201.

Abdel-Razeq H, Overmoyer B, Pohlman B, Andresen S, Kalaycio M, Dannley R, Bolwell B. Pulmonary toxicity of stamp v preparative regimen in high-dose chemotherapy (hdc) and autologous bone marrow transplantation (abmt) for breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A350.

Alvarez A, Mickiewicz E, Brosio C, Giglio R, Cinat G, Ezcurdia L, Cresta C, Gonzalez E, Noblia C. Is the number of involved resected nodes (n) after neoadjuvant chemotherapy (na) a predictive prognostic factor for disease free survival (dfs) and survival (os) for stage iii breast cancer (bc)? [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A548.

Anderson A, Ellis K, Douglas S L, Cameron D A, Leonard RCF. Emesis control in patients receiving adjuvant I.V. CMF or anthracycline chemotherapy for breast cancer [abstract]. Eur J Cancer 1999;35 Suppl 4:S378.

Anderson CM, Walters RS, Hortobagyi GN. Mediastinitis related to probable central vinblastine extravasation in a woman undergoing adjuvant chemotherapy for early breast cancer. Am J Clin Oncol 1996 Dec;19(6):566-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8931672&dopt;=Abstract

Andersson M, Storm HH, Mouridsen HT. Adjuvant chemotherapy and subsequent malignant disease [letter]. Lancet 1991;338(8771):885-6. Comment on: Lancet 1991 Aug 31;338(8766):535-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=1681236&dopt;=Abstract

Ando M, Narabayashi M, Watanabe T, Kamiya Y, Togitani K, Tanosaki R, Takenaka T, Tobinai K, Adachi I. Therapy-related leukemia and myelodysplastic syndrome in breast cancer patients treated with cyclophosphamide or anthracyclines. Jpn J Clin Oncol 1999 Jan;29(1):28-32. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10073148&dopt;=Abstract

Ang P, Cheong WK, Khoo KS. Pseudomembranous colitis in a patient treated with paclitaxel for carcinoma of the breast: a case report. Ann Acad Med Singapore 2000 Jan;29(1):132-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10748982&dopt;=Abstract

Aslani A, Begbie SD, Smith RC, Allen BJ, Levi JA, Bell DR, Wheeler HR. Body composition changes in breast cancer patients during adjuvant chemotherapy (c/t) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A191.

Aslani A, Smith RC, Allen BJ, Levi JA. Changes in body composition during adjuvant chemotherapy for breast cancer. Appl Radiat Isot 1998 May-Jun;49(5-6):637-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9569564&dopt;=Abstract

Aslani A, Smith RC, Allen BJ, Pavlakis N, Levi JA. Changes in body composition during breast cancer chemotherapy with the CMF-regimen. Breast Cancer Res Treat 1999 Oct;57(3):285-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10617305&dopt;=Abstract

Bandyk EA, Gilmore MA. Perceived concerns of pregnant women with breast cancer treated with chemotherapy. Oncol Nurs Forum 1995 Jul;22(6):975-7. Published erratum appears in Oncol Nurs Forum 1996 Jan-Feb;23(1):14. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7567615&dopt;=Abstract

Banerjee D, Ameen H, Jones WD, Harding KG, Moore K, Barrett-Lee P. Quantitative effects of adjuvant CMF on human cutaneous wound healing [abstract]. Br J Cancer 1999;80 Suppl 2:105.

Barnard K, Hansen KS. An acute cerebellar syndrome following high-dose chemotherapy and a blood cell autotransplant. Bone Marrow Transplant 1997 Jul;20(1):87-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9232265&dopt;=Abstract

Basser RL, Abraham R, To LB, Fox RM, Green MD. Cardiac effects of high-dose epirubicin and cyclophosphamide in women with poor prognosis breast cancer. Ann Oncol 1999 Jan;10(1):53-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10076722&dopt;=Abstract

Beisecker A, Cook MR, Ashworth J, Hayes J, Brecheisen M, Helmig L, Hyland S, Selenke D. Side effects of adjuvant chemotherapy: perceptions of node-negative breast cancer patients. Psychooncology 1997 Jun;6(2):85-93. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9205966&dopt;=Abstract

Berger AM. Patterns of fatigue and activity and rest during adjuvant breast cancer chemotherapy. Oncol Nurs Forum 1998 Jan-Feb;25(1):51-62. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9460773&dopt;=Abstract

Bhalla KS, Wilczynski SW, Abushamaa AM, Petros WP, McDonald CS, Loftis JS, Chao NJ, Vredenburgh JJ, Folz RJ. Pulmonary toxicity of induction chemotherapy prior to standard or high-dose chemotherapy with autologous hematopoietic support. Am J Respir Crit Care Med 2000 Jan;161(1):17-25. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10619792&dopt;=Abstract

Bines J, Oleske DM, Cobleigh MA. Ovarian function in premenopausal women treated with adjuvant chemotherapy for breast cancer. J Clin Oncol 1996 May;14(5):1718-29. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8622093&dopt;=Abstract

Breuer B, Subramaniam G, Marchello V, Giambanco V. A study of the effects of tamoxifen in the frail elderly: difficulties encountered in nursing home research. Women Health 1997;25(1):37-51. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9253137&dopt;=Abstract

Broeckel JA, Jacobsen PB, Horton J, Balducci L, Lyman GH. Characteristics and correlates of fatigue after adjuvant chemotherapy for breast cancer. J Clin Oncol 1998 May;16(5):1689-96. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9586880&dopt;=Abstract

Broet P, Scholl SM, de la Rochefordiere A, Fourquet A, Moreau T, De Rycke Y, Asselain B, Pouillart P. Short and long-term effects on survival in breast cancer patients treated by primary chemotherapy: an updated analysis of a randomized trial. Breast Cancer Res Treat 1999 Nov;58(2):151-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10674880&dopt;=Abstract

Busmanis IA, Beaty AE, Basser RL. Isolated pleural effusion with hematopoietic cells of mixed lineage in a patient receiving granulocyte-colony-stimulating factor after high-dose chemotherapy. Diagn Cytopathol 1998 Mar;18(3):204-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9523139&dopt;=Abstract

Buzdar AU, Hortobagyi GN, Singletary SE, Holmes FA, Theriault R, Walters R, Dhingra K, Booser D, Morris A, Asmar L, Wright-Browne V, Diamandidou E, Witjaksono MA, Strom E, McNeese M, Ames F. Impact of FAC-adjuvant therapy on mortality of early breast cancer: Long-term results of the M. D. Anderson Cancer Center studies. Adjuv Ther Cancer 1997;8:93-100.

Cannizzaro R, Crivellari D, Magri MD, Fornasarig M, Lombardi D, Paolello C, Sozzi M, Veronesi A. Treatment of liver toxicity in women undergoing adjuvant chemotherapy for breast cancer by ursodesoxycholic acid: A pilot study [abstract]. Hepatology 1999;30(4 Pt 2):550A.

Chan AT, Yeo W, Leung WT, Johnson PJ. Thromboembolic events with paclitaxel [letter]. Clin Oncol (R Coll Radiol) 1996;8(2):133. Comment in: Clin Oncol (R Coll Radiol) 1996;8(5):341. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8859617&dopt;=Abstract

Chap L, Shpiner R, Levine M, Norton L, Lill M, Glaspy J. Pulmonary toxicity of high-dose chemotherapy for breast cancer: a non-invasive approach to diagnosis and treatment. Bone Marrow Transplant 1997 Dec;20(12):1063-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9466279&dopt;=Abstract

Charrier S, Van Praagh I, Cure H, Achard JL, Ferriere JP, Feillel V, Bruhat M, Dauplat J, Chollet P. Ovarian function preservation following VEM (Vinorelbine, Epirubicine and Methotrexate) neo- or adjuvant chemotherapy in 49 breast cancers [abstract[. Breast Cancer Res Treat 1997;46(1):96.

Clemons MJ, Valle JW, Harris M, Ellenbogen S, Howell A. Citrobacter freundii and fatal neutropenic enterocolitis following adjuvant chemotherapy for breast cancer. Clin Oncol (R Coll Radiol) 1997;9(3):172-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9269550&dopt;=Abstract

Cobleigh MA, Bines J, Harris D, LaFollette S, Lincoln ST, Wolter JM. Amenorrhea following adjuvant chemotherapy for breast cancer [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A158.

Cole BF, Gelber RD, Goldhirsch A. A quality-adjusted survival meta-analysis of adjuvant chemotherapy for premenopausal breast cancer. International Breast Cancer Study Group. Stat Med 1995 Aug 30;14(16):1771-84. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7481209&dopt;=Abstract

Colleoni M, Bonetti M, Coates AS, Castiglione-Gertsch M, Gelber RD, Price K, Rudenstam CM, Lindtner J, Collins J, Thurlimann B, Holmberg S, Veronesi A, Marini G, Goldhirsch A. Early start of adjuvant chemotherapy may improve treatment outcome for premenopausal breast cancer patients with tumors not expressing estrogen receptors. The International Breast Cancer Study Group. J Clin Oncol 2000 Feb;18(3):584-90. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10653873&dopt;=Abstract

Colleoni M, Price KN, Castiglione-Gertsch M, Gelber RD, Coates AS, Goldhirsch A. Mortality during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil. International Breast Cancer Study Group [letter]. Lancet 1999 Jul 10;354(9173):130-1. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10408495&dopt;=Abstract

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Crivellari D, Bonetti M, Castiglione-Gertsch M, Gelber RD, Rudenstam CM, Thurlimann B, Price KN, Coates AS, Hurny C, Bernhard J, Lindtner J, Collins J, Senn HJ, Cavalli F, Forbes J, Gudgeon A, Simoncini E, Cortes-Funes H, Veronesi A, Fey M, Goldhirsch A. Burdens and benefits of adjuvant cyclophosphamide, methotrexate, and fluorouracil and tamoxifen for elderly patients with breast cancer: the international breast cancer study group trial vii. J Clin Oncol 2000;18(7):1412-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10735888&dopt;=Abstract

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Delaloge S, Di Palma M, Guerin S, Cvitkovic E, Misset JL. Second primary malignancies after low-dose anthracycline/intermediate dose cyclophosphamide-based adjuvant chemotherapy for breast cancer [abstract]. Breast Cancer Res Treat 1997;46(1):31.

Delaloge S, Palma M D, Guerin S, Cvitkovic E, Misset JL. Adjuvant doxorubicin, vincristine, cyclophosphamide, fluorouracil (avcf) for breast cancer (bc): no treatment-related leukemia at 13-year follow-up [abstract]. Proc Annu Meet Am Soc Clin Oncol 1998;17:A449.

Demark-Wahnefried W, Hars V, Conaway MR, Havlin K, Rimer BK, McElveen G, Winer EP. Reduced rates of metabolism and decreased physical activity in breast cancer patients receiving adjuvant chemotherapy. Am J Clin Nutr 1997;65(5):1495-501. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9129482&dopt;=Abstract

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Donaldson MC, Whittemore AD. Thromboembolism from occult subclavian arterial stenosis during chemotherapy for breast carcinoma. Arch Surg 1995 Feb;130(2):224-6. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=7848096&dopt;=Abstract

Dranitsaris G, Tran TM. Economic analyses of toxicity secondary to anthracycline-based breast cancer chemotherapy. Eur J Cancer 1995 Dec;31A(13-14):2174-80. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8652238&dopt;=Abstract

Duvic M, Lemak NA, Valero V, Hymes SR, Farmer KL, Hortobagyi GN, Trancik RJ, Bandstra BA, Compton LD. A randomized trial of minoxidil in chemotherapy-induced alopecia. J Am Acad Dermatol 1996;35(1):74-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8682968&dopt;=Abstract

Eek RW, Falkson CI. Extended survival in 80 patients with operable, locoregionally recurrent breast cancer treated with chemotherapy. Am J Clin Oncol 1998 Oct;21(5):501-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9781609&dopt;=Abstract

Eibl B, Schwaighofer H, Nachbaur D, Marth C, Gachter A, Knapp R, Bock G, Gassner C, Schiller L, Petersen F, Niederwieser D. Evidence for a graft-versus-tumor effect in a patient treated with marrow ablative chemotherapy and allogeneic bone marrow transplantation for breast cancer. Blood 1996 Aug 15;88(4):1501-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8695872&dopt;=Abstract

Ejlertsen B, Dombernowsky P, Mouridsen H, Kamby C, Kjaer M, Rose C, Andersen K/Jensen MB, Bengtsson NO, Bergh J. Comparable effect of ovarian ablation (oa) and cmf chemotherapy in premenopausal hormone receptor positive breast cancer patients (prp) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A248.

Erselcan T, Kairemo KJ, Wiklund TA, Hernberg M, Blomqvist CP, Tenhunen M, Bergh J, Joensuu H. Subclinical cardiotoxicity following adjuvant dose-escalated FEC, high-dose chemotherapy, or CMF in breast cancer. Br J Cancer 2000 Feb;82(4):777-81. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10732745&dopt;=Abstract

Espanol I, Muniz-Diaz E, Alonso MC, Pujol-Moix N. Severe immune thrombocytopenia during formestane treatment [letter]. Haematologica 1998 Oct;83(10):953-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9830809&dopt;=Abstract

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Fairclough DL, Fetting JH, Cella D, Wonson W, Moinpour CM. Quality of life and quality adjusted survival for breast cancer patients receiving adjuvant therapy. Qual Life Res 1999;8(8):723-31. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10855346&dopt;=Abstract

Feigin R, Greenberg A, Ras H, Hardan Y, Rizel S, Efraim TB, Stemmer SM. The psychosocial experience of women treated for breast cancer by high-dose chemotherapy supported by autologous stem cell transplant: A qualitative analysis of support groups. Psycho Oncology 2000;9(1):57-68. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10668060&dopt;=Abstract

Fernando IN, Powles TJ, Ashley S, Grafton D, Harmer CL, Ford HT. An acute toxicity study on the effects of synchronous chemotherapy and radiotherapy in early stage breast cancer after conservative surgery. Clin Oncol 1996;8(4):234-8.

Fisher DC, Sherrill GB, Hussein A, Rubin P, Vredenburgh JJ, Elkordy M, Ross M, Petros W, Peters WP. Thrombotic microangiopathy as a complication of high-dose chemotherapy for breast cancer. Bone Marrow Transplant 1996 Jul;18(1):193-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8832014&dopt;=Abstract

Fisher DC, Vredenburgh JJ, Petros WP, Hussein A, Berry DA, Elkordy M, Rubin P, Gilbert CJ, Peters WP. Reduced mortality following bone marrow transplantation for breast cancer with the addition of peripheral blood progenitor cells is due to a marked reduction in veno-occlusive disease of the liver. Bone Marrow Transplant 1998;21(2):117-22. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9489626&dopt;=Abstract

Ganz PA. Cognitive dysfunction following adjuvant treatment of breast cancer: a new dose-limiting toxic effect? [editorial]. J Natl Cancer Inst 1998 Feb 4;90(3):182-3. Comment on: J Natl Cancer Inst 1998 Feb 4;90(3):210-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9462670&dopt;=Abstract

Gaston-Johansson F, Fall-Dickson JM, Bakos AB, Kennedy MJ. Fatigue, pain, and depression in pre-autotransplant breast cancer patients. Cancer Pract 1999;7(5):240-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10687593&dopt;=Abstract

Gelber RD, Bonetti M, Cole BF, Gelber S, Goldhirsch A. Quality of life assessment in the adjuvant setting: is it relevant? International Breast Cancer Study Group. Recent Results Cancer Res 1998;152:373-89. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9928573&dopt;=Abstract

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Glasziou PP, Cole BF, Gelber RD, Hilden J, Simes RJ. Quality adjusted survival analysis with repeated quality of life measures. Stat Med 1998;17(11):1215-29. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9670411&dopt;=Abstract

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Goodman A, Cagliero E. Megestrol-induced clinical adrenal insufficiency. Eur J Gynaecol Oncol 2000;21(2):117-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10843465&dopt;=Abstract

Goodwin PJ, Esplen MJ, Winocur J, Brazel S, Miller A, Butler K, Pritchard KI. Multidisciplinary weight (w) management program in primary breast cancer (bc): development and early results [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A155.

Green DM. Late effects of adjuvant chemotherapy for the treatment of cancer in children and adolescents. Adjuv Ther Cancer 1997;8:33-50.

Haider M. Effect of adjuvant chemotherapy on the circulating levels of pituitary hormones in postmenopausal breast cancer patients. Ann Saudi Med 1995;15(5):470-2.

Headley JA, Theriault RL, LeBlanc AD, Vassilopoulou-Sellin R, Hortobagyi GN. Pilot study of bone mineral density in breast cancer patients treated with adjuvant chemotherapy. Cancer Invest 1998;16(1):6-11. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9474245&dopt;=Abstract

Hecht JR, Lembo T, Chap L. Prolonged nausea and vomiting after high dose chemotherapy and autologous peripheral stem cell transplantation in the treatment of high risk breast carcinoma. Cancer 1997 May 1;79(9):1698-702. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9128984&dopt;=Abstract

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Hirvikoski PP, Kumpulainen EJ, Johansson RT. CNF combination as adjuvant treatment in breast cancer patients is well tolerated. Anticancer Drugs 1997 Apr;8(4):376-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9180391&dopt;=Abstract

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HjiYiannakis P, Yarnold JR. Mixing anthracyclines and radiotherapy in early breast cancer: how safe is it? Eur J Cancer 1996 Dec;32A(13):2374-7. Corrected and republished article originally printed in Eur J Cancer 1996 Oct;32A(11):1845-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9038631&dopt;=Abstract

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Hurny C, Bernhard J, Coates A, Peterson HF, Castiglione-Gertsch M, Gelber RD, Rudenstam CM, Collins J, Lindtner J, Goldhirsch A, Senn HJ. Responsiveness of a single-item indicator versus a multi-item scale: assessment of emotional well-being in an international adjuvant breast cancer trial. Med Care 1996 Mar;34(3):234-48. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8628043&dopt;=Abstract

Hurny C, Bernhard J, Coates AS, Castiglione-Gertsch M, Peterson HF, Gelber RD, Forbes JF, Rudenstam CM, Simoncini E, Crivellari D, Goldhirsch A, Senn HJ. Impact of adjuvant therapy on quality of life in women with node-positive operable breast cancer. International Breast Cancer Study Group . Lancet 1996 May 11;347(9011):1279-84. Published erratum appears in Lancet 1997 Jul 26;350(9073):298. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8622502&dopt;=Abstract

Jacobsen PB, Hann DM, Azzarello LM, Horton J, Balducci L, Lyman GH. Fatigue in women receiving adjuvant chemotherapy for breast cancer: characteristics, course, and correlates. J Pain Symptom Manage 1999 Oct;18(4):233-42. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10534963&dopt;=Abstract

Kailajarvi M, Ahokoski O, Virtanen A, Salminen E, Irjala K. Serum cholesterol, HDL cholesterol and triglycerides during adjuvant CMF therapy in premenopausal breast cancer patients [abstract]. Eur J Cancer 1999;35 Suppl 4:S210.

Kailajarvi M, Ahokoski O, Virtanen A, Salminen E, Irjala K. Thyrotropin, free thyroxine, and free triiodothyronine during adjuvant CMF therapy in premenopausal breast cancer patients [abstract]. Clin Chem Lab Med 1999;37 Suppl:S183.

Kajdaniuk D, Marek B. Influence of adjuvant chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil on plasma insulin-like growth factor-I and chosen hormones in breast cancer pre-menopausal patients. J Clin Pharm Ther 2000 Feb;25(1):67-72. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10771466&dopt;=Abstract

Kajdaniuk D, Marek B, Swietochowska E, Ciesielska-Kopacz N, Nowak B, Wielkoszynski T. Transforming-like growth factor beta1 (TGFbeta1) and its interactions with chosen hormones in stage II breast cancer patients on adjuvant chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil [abstract]. Breast Cancer Res Treat 1999;57(1):91.

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Kollmannsberger C, Hartmann JT, Kanz L, Bokemeyer C. Risk of secondary myeloid leukemia and myelodysplastic syndrome following standard-dose chemotherapy or high-dose chemotherapy with stem cell support in patients with potentially curable malignancies. J Cancer Res Clin Oncol 1998;124(3-4):207-14. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9619748&dopt;=Abstract

Kornblith A, Herndon J, Zuckerman E, Viscoli C, Horwitz R, Weiss R, Cooper MR, Crawford J, Borden E, Perry M, Budman D, Norton L, Holland J. Can social support reduce breast cancer patients' psychological distress when faced with stressful life events? [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A2276.

Kumpulainen EJ, Hirvikoski PP, Pukkala E, Johansson RT. Cancer risk after adjuvant chemo- or chemohormonal therapy of breast cancer. Anticancer Drugs 1998 Feb;9(2):131-4. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9510498&dopt;=Abstract

Larson PJ, Hanak KJ, Blumson PS. Challenges. The psychobiologic effect of chemotherapy on premenopausal women with breast cancer. Innov Breast Cancer Care 1997 Apr;2(3):48-9, 61-2.

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Lecomte S, Lemenager M, Duquenne I, Crepin G, Bonneterre J. Quality of life in breast cancer patients receiving adjuvant chemotherapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1995;14:A900.

Lekander M, Furst CJ, Rotstein S, Blomgren H, Fredrikson M. Social support and immune status during and after chemotherapy for breast cancer. Acta Oncol 1996;35(1):31-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8619937&dopt;=Abstract

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Linassier C, Barin C, Bremond JL, Benboubker L, Petit A, Georget MT, Delain M, Binet C, Lamagnere JP, Colombat P. Secondary leukemia in breast cancer patients after exposure to an association of mitoxantrone, fluorouracil and cyclophosphamide and radiotherapy [abstract]. Proc Annu Meet Am Soc Clin Oncol 1996;15:A1061.

Locatelli M, Colleoni M, Noberasco C, Nole F, Orlando L, Munzone E, Peruzzotti G, Goldhirsch A. Hepatic toxicity from cyclophosphamide, methotrexate, fluorouracil (CMF regimen) [letter]. Ann Oncol 1999 Nov;10(11):1394-5. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10631475&dopt;=Abstract

Loprinzi CL, Athmann LM, Kardinal CG, O'Fallon JR, See JA, Bruce BK, Dose AM, Miser AW, Kern PS, Tschetter LK, Rayson S. Randomized trial of dietician counseling to try to prevent weight gain associated with breast cancer adjuvant chemotherapy. Oncology 1996 May-Jun;53(3):228-32. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=8643226&dopt;=Abstract

Lower EE, Blau R, Gazder P, Tummala R. The risk of premature menopause induced by chemotherapy for early breast cancer. J Womens Health Gend Based Med 1999 Sep;8(7):949-54. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10534297&dopt;=Abstract

Madajewicz S, Matei D, Hentschel P, Kudelka A, Abel W, Fiore JJ, DaCosta NA, Pendyala L. Actual 5-year survival of patients with stage IIIB breast carcinoma: phase II trial of methotrexate, vinblastine, adriamycin, cisplatin, and folinic acid. Cancer Invest 1999;17(7):463-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10518189&dopt;=Abstract

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Saarto T, Blomqvist C, Valimaki M, Makela P, Sarna S, Elomaa I. Chemical castration induced by adjuvant cyclophosphamide, methotrexate, and fluorouracil chemotherapy causes rapid bone loss that is reduced by clodronate: a randomized study in premenopausal breast cancer patients. J Clin Oncol 1997 Apr;15(4):1341-7. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9193325&dopt;=Abstract

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Shapiro CL, Neuberg D, Scholnidk J, Keating J, Kearns C, Shulman L, Parker L, Gore SM, Tishler S, Friedlander R, Lynch T, Kaelin C, Hayes D, LeBoff MS. Chemotherapy-induced ovarian failure (chemo ov fail) is associated with significant bone loss in early stage breast cancer patients (pts) [abstract]. Proc Annu Meet Am Soc Clin Oncol 1997;16:A500.

Shapiro DE, Boggs SR, Rodrigue JR, Urry HL, Algina JJ, Hellman R, Ewen F. Stage II breast cancer: differences between four coping patterns in side effects during adjuvant chemotherapy. J Psychosom Res 1997 Aug;43(2):143-57. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9278904&dopt;=Abstract

Shimozuma K, Katsumata N, Ohashi Y, Makino H, Takashima S, Sonoo H, Watanabe T. Impact of surgical adjuvant chemotherapy on quality of life (qol) of patients with breast cancer (bc)---a phase III randomized trial comparing uft (uracil/tegafur) with cmf in high-risk node negative patients [abstract]. Proc Annu Meet Am Soc Clin Oncol 1999;18:A2236.

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Steinberg JL, Yeo W, Zhong S, Chan JY, Tam JS, Chan PK, Leung NW, Johnson PJ. Hepatitis B virus reactivation in patients undergoing cytotoxic chemotherapy for solid tumours: precore/core mutations may play an important role. J Med Virol 2000 Mar;60(3):249-55. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=10630955&dopt;=Abstract

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Wyatt GK, Friedman LL. Physical and psychosocial outcomes of midlife and older women following surgery and adjuvant therapy for breast cancer. Oncol Nurs Forum 1998 May;25(4):761-8. Available from: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db;=PubMed&list;_uids=9599359&dopt;=Abstract

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### 6d. Decision-Making Analyses

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