## Monsanto Company CR240-13E3 Page 1 of 166 

# Title

Amended Application for an Experimental Use Permit to Test MON 87411, Combined Trait Insect Control Corn, Combinations Necessary for their Production, and Controls; (EPA File Symbol 524-EUP-104).

Test Guideline Not applicable for this EUP application

Data Requirement

40 CFR Part 172

Authors

M. Groth

H. Kannall

C. Patino

Submission Date

October 3, 2013

Report Generated By

Monsanto Company

Registrant Submitting

Monsanto Company 800 North Lindbergh Blvd. St. Louis, MO 63167

Submission ID

CR240-13E3

Page Count

1 of 166

Volume 1

### The text below applies only to use of the data by the United States Environmental Protection Agency (U.S. EPA) in connection with the provisions of the Federal Insecticide, Fungicide

and Rodenticide act (FlFRA).

CLAIM OF CONFIDENTIALITY

Information claimed as confidential on the basis of its falling within the scope ofFIFRA

section 10( d)(l )(A), (B), or (C) has been removed to a confidential appendix, and is cited by

cross-reference

### ~~be~t"dy submission.

Submitter:

# ~d (":' ( Date: October 3. 2013

Name: Mark E. Groth. B.A.

Company: Monsanto Company

We submit this material to the U.S. EPA specifically under the requirements set forth in

FIFRA as amended, and consent to the use and disclosure of this material by the EPA strictly

in accordance with FIFRA. By submitting this material to the EPA in accordance with the

method and format requirements contained in PR Notice 2011-3, we reserve and do not waive

any rights involving this material that are or can be claimed by the company notwithstanding

this submission to the EPA.

In the United States, the above statement supersedes all other statements of confidentiality

that may occur elsewhere in this document.

THESE DATA MAY BE CONSIDERED CONFIDENTIAL IN COUNTRIES

OUTSIDE THE UNITED STATES.

Monsanto Company CR240-13E3 Page 2 of 166

### GLP Compliance Statement

This Administrative Volume does not meet the U.S. EPA Good Laboratory Practice requirements as specified in 40 CFR Part 

### 160. This Experimental Use Permit Administrative

Volume does not comprise a study under 40 CFR 

### § 160.3.

# S'b""'M~/**~~** Mark E. Groth, B.A. 

### Date:

Monsanto Company

Study Director:

# ~7**~L** 0e'e

. Bookout, M.S. Date:

Monsanto Company

Monsanto Company CR240-13E3 Page 3 of 166

### OPP Identifier 

# &EPA United States Nnmber
ENVIRONMENTAL PROTECTION AGENCY

Washington, DC 20460 

### 524-EUP-104

Office of Pesticide Programs (7505C) Application for Experimental Use Permit to Ship and

Use a Pesticide for Experimental Pnrposes Only

1. Type of Application 2. Briefly explain (attach a separate sheet if necessary) 

# D 0' Amendment (See No.2) Groth, M., Kannall, H., Patino, C. 2013. Amended Application for an

New Experimental Use Permit to Test MON 87411, Combined Trait Insect 

# D Control corn, Combinations Necessary for their Production, and

Extension (Give Permit Number be/ow) Controls; (EPA File Symbol 524-EUP-104).

Permit Number 

### 524-EUP-I04

3. Name and address of Firm/Person to Whom the Experimental Use 4. Name and address of Shipper only if shipment is intended or if

Permit is to be Issued (include ZIP Code) (Type or Print) different from applicant's name and address (include Zip Code)

Monsanto Company (Type or Print)
800 NOlih Lindbergh Blvd.

SI. Louis, MO 63167

EPA Company Number 524 6. Is product registered with EPA?

5. 

### Name of Product: Corn RootwormwProtected, Glyphosale- 

# 0 No Tolerant Com MON 87411, and Lepidopteran and Corn Rootwonn

# D Protected, Glyphosate- and Glufosinate-Tolerant Corn stack Yes (Give Registration Number of File Symbol below)
combinations Registration Number File Symbol

7. Total Quantity of Product Proposed for ShipmenUUse 8. Acreage or Area to be Treated 9. Proposed Period of ShipmenUUse

Pounds of formulated product 

### 1,497,820 lbs seed 7,776 non-PIP

4.8lbsCrylF 13.61bs Cry3Bbl 20,361 nonregistered PIP

5.7 lbs CrylA.I05 61.71bsCry34Abl 11,508 registered PIP 

### February 15,2014-

2.6 Ibs Cry2Ab2 1.51bs Cry35AhJ 6877 border acres 

### February 28, 2016

22.5 Ibs Vip3Aa20 46,522 TOTAL ACRES

1.1 x IO·5lbsDvSnt7dsRNA

Pounds of active ingredient

10. Places from which shipped 11. CropsfSite to be Treated

Monsanto Company, St. Louis, MO; Seed Companies and Licensees 

### Corn

a

12. Specify the name and number of the contact person most familiar

# 13'7)Y,0:r?PA~untative with this application. 

### Mark E. Groth 14. Title 

### Regulatory Affairs 15. Date Signed


### Phone: (314) 694-3369 Manager October 3, 2013

Certification

This is to certify that food and feed derived from the experimental program will not be used or offered for consumption or sale for consumption,

except by laboratory or experimental animals, if illegal residues are present in or on such food or feed.

I certify that the statements I have made on this form and all attachments thereto are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine or imprisonment, or both, under applicable law.



### Below fOI"EPA Use Only .' ". ,

...... ". '. 

### ,. ..... 

### .',

. . ..

.

In any correspondence 'on this applicaUon, refer to this number .•..**ReceIv~d** by:**EPA~OPP** Registration



### . '....



# . .•........

. .' Division. Washington. DC 20,460

Normal review time, indicates 'that'processi'ng 'of-this application'shc)ljld be**cbmpi~ted** by (date)



# ..

, '.' .'

. . ".

.. . .' .,'

Nanie of EPA Contact Person ....**T.el~phone** Number

...... .'



# ... , "

. . ' . .



### Monsanto Company CR240-13E3 Page 6 of 166

## Monsanto Company CR240-13E3 Pages 7 - 117 of 166 EPA Form 8540-4 Confiden tial Statement of Formula

Information claimed confidential has been remove d to the confidential attachment. See Cross Reference 1.

# &EPA UNITED STATES ENVIRONMENTAL PROTECTION AGENCY



### 401 M Street, S. W.

WASHINGTON, 

### D.C. 20460

Papcrworl" Reduction Act Notice: The public reporting burden for this collection of information is estimated to average 1.25 hours per response
for registration and 0.25 hours per response for reregistration and special review activities, including time for reading the instructions and completing the necessary forms, Send comments regarding burden estimate or any other aspect of this collection of information, including suggestions for reducing the burden 10 Director, OPPE Information Management Division (2137), U.S. Environmental Protection Agency, 401 M
Street, S. W., Washington DC, 20460. Do not send the completed form to this address.



### Certification with Respect to Citation of Data

Applicant's/Registratant's Name, Address, and Telephone Number: EPA Registration Number 

### I File Symbol:

Monsanto Company, 800 

### N0l1h Lindbergh Blvd., St. 

### Louis, MO 63167 524-EUP-104

Tel. (314) 694-3369

Active Ingredient)s) andlor representative test compound(s): DvSnf7 dsRNA Date:
and the genetic material (vector PV-ZMIR10871) neccssaty for its production in corn; 

### October 

### 3,2013 Bacillus tlllll'ingiensis CryIA.IOS, Cl'y2Ab2, CrylF, Cry3Bbl, Cry34Abl, Cry35Abl, Vip3Aa20 and the genetic material (vectors PV-ZNfIR245, PI-IP8999, PV-ZMIR39,

PHP17622, pNOV1300), neceSSaIY for their production in corn. 

### General Use Pattern(s) (list all those claimed for this product using 

### 40 Product Name:



### CFR Part 

### 158: Corn Rootwonn-Protected, Glyphosate-'l'olerant Corn,

Terrestrial field crop MON 87411, and Lepidopteran and Corn RootwormProtected, Glyphosate- and Glufosinate-Tolerant Corn

stack combinations



### NOTE: Ifyoul' product is a 

### 100% repackaging of another purchased EPA-registered product labeled for all the same uses on

your label, you do not need to submit this form. You must submit the Formulator's Exemption Statement (EPA Form 

### 8570-27). 

# D 1 am responding to a Data-Call-in Notice, and have included with this form a list of companies sent offers of compensation 

### (the Data Matrix form should be used for this purpose).

Section I: METHOD OF DATA SUPPORT (Check one method only) 

# D I am using the cite-all method of support, and have included with

# ~ I am using the selective method of support (or cite-aU option

this form a list of companies set offers of compensation (the under the selective method), and have included with this form a
Data Matrix Form should be used for this purpose). completed list of data requirements (the Data Matrix form must 

### be used).

Section II: GENERAL OFFER TO PAY 

# D [Required if using the cite-all method or when using the cite-all option under the selective method to satisfy one or more data requirements]

I 

### herebv off< 

### '" aoree to Dav .10

, 

### . with reoard 10 

### the loflhis

. 10 

### Ihe exlenl reouired bv
Section III: CERTIFICATION

I certify that this application for registration, this form for reregistration, or this Data-Call-In response is supported by all data submitted or cited

in the application for registration, the form for registration, or the Data-Call-In response. In addition, if the cite-all option or cite-all option under the

selective method is indicated in Section 1, this application is supported by all data in the Agency's files that (1) concern the properties or effects of this product or an identical or substantially similar product, one or more of the ingredients in this product; and (2) is a type of data that would be required to

be submitted under the data requirements in effect on the date of approval of this application if the application sought the initial registration of a product

of identical or similar composition and uses.

# ~ I certify that for each exclusive use study cited in support of this registration or reregistration, that I am the original data submitter or that I have

obtained the written permission of the original data submitter to cite that study.

I certify that for each study cited in support of this registration or reregistration that is not an exclusive use study, either: (a) I am the original data submitter; (b) I have obtained the permission of the original data submitter to use the study in support of this application; (c) all periods of eligibifity for compensation have expired for the study; (d) the study is in the public literature; (e) I have notified in writing the company that submitted the study and

have offered (i) to pay compensation to the extent required by sections 3(c)(1)(F) andlor 3(c)(2)(8) of FIFRA; and (ii) to commence negotiations to

determine the amount and terms of compensation, if any, to be paid for the use of the study.

I certify that in all instances where an offer of compensation is required, copies of all offers to pay compensation and evidence of their delivery in

accordance with sections 3(c)(1)(F) andlor 3(c)(2)(8) of FIFRA are available and will be submitted to the Agency upon request. Should I fail to produce

such evidence to the Agency upon request. I understand that the Agency may initiate action to deny, cancel or suspend the registration of my product in conformity with FIFRA.

I certify that the statements I have**ma~~~is** form and all attachments to It are true, accurate, and complete. I acknowledge that

any knowinaiy.false of**misl~;¥ting s!i!~ment**  9:p.unishable b fine or imprisonment of both under the applicable law.

# Signature~**!/«~** Date Typed or Printed Name and Title 

### Mark E. 

### Groth October 3, 2013 Regulatory Affairs Manager



### Monsanto Company 

### CR240-13E3 Page 

### 118 of 

### 166

## Monsanto Company CR240-13E3 Page 119 of 166 Section A. Product Description

Monsanto Company is requesting an EUP to test a new PIP technology MON 87411, combined trait insect control corn, comb inations necessary for their production, and

controls.

Development and testing of new PIPs and PI P combinations providing multiple modes of action against CRW and Lepidopteran corn pest s is an important component of producing highly efficacious products th at also support durable IRM. The PIP events comprising the combined trait products in this EUP include five regi stered corn events (MON 89034, EPA Reg. No. 524-576; TC1507, EPA Reg. No. 68467-2; MIR162, EPA Reg. No. 67979-14; MON 88017, EPA Re g. No. 524-551; and DA S-59122-7, EPA Reg. No. 68467-5), and one corn events representing a new class of PIP activ e against CRW spp. (MON 87411).

Using biotechnology methods, Monsanto Co mpany has develope d MON 87411, that confer resistance to corn rootworm (CRW; Diabrotica spp.). MON 87411 contains a suppression cassette with an inverted re peat sequence (DvSnf7) derived from Diabrotica virgifera . The expression of the DvSnf7 suppressi on cassette results in the formation of a double stranded RNA (dsRNA) transcript. Upon consumption by the CRW pest, the plant-produced DvSnf7 dsR NA in MON 87411 result in the down-regulation of the targeted Snf7 gene and eventual CRW mortality. MON 87411 also produce the Cry3Bb1 protein to protect against CRW larval f eeding. In addition, MON 87411 are Roundup Ready  

## corn events that produce the 5-e nolpyruvylshikimate-3-phosphate synthase protein from Agrobacterium sp. strain CP4 (CP4 EPSPS) , which confers tolerance to glyphosate, the active ingredient in Roundup  

## agricultural herbicides.

All of the above registered corn PIP produc ts, produce active ingr edients derived from Bacillus thuringiensis ( B.t. ). Crystal proteins derived from B.t. have been safely used in biotechnology-derived crops for over a decade. EPA has reviewed and registered the Cry1A.105, Cry2Ab2, Cry1F, Vip3Aa20, Cry3 Bb1, and Cry34Ab1/Cry35Ab1 proteins as produced in corn and/or cotton. The e nvironmental human health safety of these registered PIPs and proteins has been dem onstrated and they are exempted from the requirement of a tolerance (see Section C on toxicity data within this submission). The DvSnf7 insecticidal nucleic acid component in MON 87411 are currently being evaluated for safety and efficacy. Nucleic acids are cons idered to be “generally recognized as safe” (GRAS) by the U.S. Food and Drug Administration (FDA) ( 1992) and exempt from the requirement of a tolerance under the Federa l Food Drug and Cosmetic Act by the U.S. Environmental Protection Agency (EPA).

 

## Roundup and Roundup Ready are registered trad emarks of Monsanto Technology LLC.

## Monsanto Company CR240-13E3 Page 120 of 166 Section B. Proposed Experimental Use Permit Label

The attached master label for testing under the experimental use permit contains the following:

 a proposed label for MON 89034 x TC1507 x MIR162 x MON 88017 x MON

87411 x DAS-59122-7 (vector PV-ZMIR245, vector PHI8999, vector pNOV1300, vector PV-ZMIR39, vect or PV-ZMIR10871, vector PHP17662)

This proposed label contains the highest order stack incl uding all single PIP events

included within this EUP. Smaller order st acks or intermediates may also be shipped under this EUP as per the following Master Label.

## Monsanto Company CR240-13E3 Page 121 of 166 

# MASTER LABEL

EPA EXPERIMENTAL USE PERMIT NUMBER 524-EUP-104 Plant-Incorporated Protectant Label



# Keep Out Of Reach Of Children

CAUTION

This Master Label for testing under the Ex perimental Use Permit (EUP) contains the following 46 materials. This Master Label will accompany each shipment of viable plant material required for trials co nducted at the release site, in accordance with the EUP. The highest order stack is listed including every PIP material

included within the EUP. All lower ord er stacks are covered under this Master

Label:

1. Lepidopteran-Protected Corn: MON 89034.

2. Lepidopteran-Protected, Glufos inate-Tolerant Corn: TC1507.

3. Lepidopteran-Protected Corn: MIR162.

4. Corn rootworm-Protected, Glyphosate-Tolerant Corn: MON 88017.

5. Corn rootworm-Protected, Glyphosate-Tolerant Corn: MON 87411.

6. Corn rootworm-Protected, Glufos inate-Tolerant Corn: Cry34/35Ab1 (DAS-59122-7).

7. Lepidopteran-Protected, Glufosinat e-Tolerant Corn: MON 89034 × TC1507.

8. Lepidopteran-Protected Corn: MON 89034 × MIR162.

9. Lepidopteran-Protected, Corn rootwo rm-Protected, Glyphosate-Tolerant

Corn: MON 89034 × MON 88017.

10. Lepidopteran-Protected, Corn rootwo rm-Protected, Glyphosate-Tolerant

Corn: MON 89034 × MON 87411.

11. Lepidopteran-Protected, Corn rootworm -Protected, Glufosinate-Tolerant

Corn: MON 89034 × DAS-59122-7.

12. Lepidopteran-Protected, Glufosinat e-Tolerant Corn: MON 89034 × TC1507 ×

MIR162. FOR EXPERIMENTAL USE ONLYNot for sale to or use by any person other than a participant or cooperator of the EPAapproved Experimental Use Program.

For use only at a site of a participant or cooperator and in accordance with the terms and conditions of the Experimental Use Permit. This labeling must be in possession of the user at the time of planting.

For use in States (Alabama, Arkansas, Calif ornia, Colorado, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Michigan, Minnesota, Mississippi, Missouri, Nebras ka, North Carolina, North Dakota, Ohio, Oklahoma, Pennsylvania, South Carolina, South Da kota, Tennessee, Texas, Washington, Wisconsin) and the Commo nwealth of Puerto Rico.

## Monsanto Company CR240-13E3 Page 122 of 166 13. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × TC1507 × MON 88017.

14. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × TC1507 × MON 87411.

15. Lepidopteran-Protected, Corn rootworm -Protected, Glufosinate-Tolerant

Corn: MON 89034 × TC1507 × DAS-59122-7.

16. Lepidopteran-Protected, Corn rootwo rm-Protected, Glyphosate-Tolerant

Corn: MON 89034 × MIR162 × MON 88017.

17. Lepidopteran-Protected, Corn rootwo rm-Protected, Glyphosate-Tolerant

Corn: MON 89034 × MIR162 × MON 87411.

18. Lepidopteran-Protected, Corn rootworm -Protected, Glufosinate-Tolerant

Corn: MON 89034 × MIR162 × DAS-59122-7.

19. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × MON 88017 × DAS-59122-7.

20. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × TC1507 × MIR162 × MON 87411.

21. Lepidopteran-Protected, Corn rootworm -Protected, Glufosinate-Tolerant

Corn: MON 89034 × TC1507 × MIR162 × DAS-59122-7.

22. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × TC1507 × MON 88017 ×

DAS-59122-7.

23. Lepidopteran-Protected, Corn rootwo rm-Protected, Glyphosate-Tolerant

Corn: MON 89034 × MON 88017 × MON 87411.

24. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × MON 87411 × DAS-59122-7.

25. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × TC1507 × MON 87411 ×

DAS-59122-7.

26. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × MIR162 × MON 88017 ×

DAS-59122-7.

27. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × MIR162 × MON 87411 ×

DAS-59122-7.

28. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × TC1507 × MIR162 × MON 88017

× DAS-59122-7.

29. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × TC1507 × MIR162 × MON 87411

× DAS-59122-7.

30. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MON 89034 × TC1507 × MON 88017 × MON

87411 × DAS-59122-7.

31. Lepidopteran-Protected, Glufosinat e-Tolerant Corn: TC1507 × MIR162.

32. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: TC1507 × MON 88017.

33. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: TC1507 × MON 87411.

## Monsanto Company CR240-13E3 Page 123 of 166 34. Lepidopteran-Protected, Corn rootworm -Protected, Glufosinate-Tolerant

Corn: TC1507 × DAS-59122-7.

35. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: TC1507 × MIR162 × MON 87411.

36. Lepidopteran-Protected, Corn rootworm -Protected, Glufosinate-Tolerant

Corn: TC1507 × MIR162 × DAS-59122-7.

37. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: TC1507 × MON 88017 × DAS-59122-7.

38. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: TC1507 × MON 87411 × DAS-59122-7.

39. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: TC1507 × MIR162 × MON 87411 ×

DAS-59122-7.

40. Lepidopteran-Protected, Corn rootworm -Protected, Glufosinate-Tolerant

Corn: MIR162 × DAS-59122-7.

41. Lepidopteran-Protected, Corn root worm-Protected, Glyphosate- and

Glufosinate-Tolerant Corn: MIR162 × MON 87411 × DAS-59122-7.

42. Lepidopteran-Protected, Corn rootwo rm-Protected, Glyphosate-Tolerant

Corn: MIR162 × MON 87411.

43. Corn rootworm-Protected, Glyphosate-Tolerant Corn: MON 88017 ×

MON 87411.

44. Corn rootworm-Protected, Glyphosate and Glufosinate-Tolerant Corn:

MON 88017 × MON 87411 × DAS-59122-7.

45. Corn rootworm-Protected, Glyphosate- and Glufosinate-Tolerant Corn:

MON 88017 × DAS-59122-7.

46. Corn rootworm-Protected, Glyphosate- and Glufosinate-Tolerant Corn:

MON 87411 × DAS-59122-7.

## Monsanto Company CR240-13E3 Page 124 of 166 DIRECTIONS FOR USE Use of this seed in a manner inconsistent with the terms of this Experimental Use Permit (EUP) is a violation of Fede ral law. The contents may only be used according to the approved EUP program. Cooperato rs and Participants must ha ve at least one copy of the protocols in Section G prior to initiati ng any research with the contents.

Test plots must not be located within 1⁄4 of a mile from the habitats of endangered/threatened lepidopteran and coleopteran species as listed by the US Fish and

Wildlife Service.

STORAGE AND DISPOSAL Do not contaminate water, food, or feed by storage and disposal.

Storage Store in a secure, cool, and dr y place inaccessible to children.

Seed and Plant Disposal Any seed and/or plant material not used in these experiments must be returned to Monsanto Company or seed company partners/affiliates, or disposed of as specified in the field protocols in Section G.

Container Disposal Do not reuse bag. Ensure that the bag is co mpletely empty of seed before disposal. Dispose as specified in Section G.

## Monsanto Company CR240-13E3 Page 125 of 166 

# Monsanto EUP Shipment Summary Label

524-EUP-104

Event (See pages 1-3 for list of events) Net contents (lbs)

## Monsanto Company CR240-13E3 Page 126 of 166

# Lepidopteran-Protected, Coleopteran-Protected, GlyphosateTolerant, Glufosinate-Tolerant Corn: MON 89034 × TC1507 ×

MIR162 × MON 88017 × MON 87411 × DAS-59122-7

This package contains corn seed producing any of the following insecticidal proteins

from Bacillus thuringiensis, and/or a double stranded RNA (dsRNA) transcript comprising an inverted repeat sequence (DvSnf7) derived from Diabrotica virgifera

. These proteins and/or dsRNA are effective in controlling feeding damage caused by lepidopteran and/or coleopteran insect pests.

Active Ingredients:

Bacillus thuringiensis Cry1A.105 protein and the genetic material necessary for its production (vector PV-ZMIR245) in corn ev ent MON 89034 (OECD Unique Identifier: MON-89Ø34-3) ................................................................................................. ≤ 0.0056%*

Bacillus thuringiensis Cry2Ab2 protein and the genetic material necessary for its production (vector PV-ZMIR245) in corn ev ent MON 89304 (OECD Unique Identifier: MON-89Ø34-3) ................................................................................................. ≤ 0.0057%*

Bacillus thuringiensis Cry1F protein and the genetic material necessary for its production (construct PHP8999; event TC1507) in corn ....................................... <0.0010 – 0.235%**

Bacillus thuringiensis Vip3Aa20 insecticidal protein a nd the genetic material necessary for its production (via elements of vect or pNOV1300) in corn event MIR162 (OECD Unique Identifier SYN-IR162-4) ..................................................................... ≤ 0.00751%*

Bacillus thuringiensis Cry3Bb1 protein and the geneti c material necessary for its production (vector PV-ZMIR39 and/or PV -ZMIR10871) in corn event MON 88017 (OECD Unique Identifier M ON-88Ø17-3) and/or MON 87411 ....................... ≤ 0.0070%*

dsRNA transcript comprising a DvSnf7 i nverted repeat sequence derived from Diabrotica virgifera , and the genetic material nece ssary for its production (vector PV-ZMIR10871) in corn event MON 87411............................................ ≤ 0.000000344%*

Bacillus thuringiensis Cry34Ab1 insecticidal crysta l protein and the genetic material necessary for its produc tion (construct PHP17662) in event

DAS-59122-7 corn ................................................................................ 0.000867-0.0088%*

Bacillus thuringiensis Cry35Ab1 insecticidal crysta l protein and the genetic material necessary for its produc tion (construct PHP17662) in event

DAS-59122-7 corn .............................................................................. 0.000413-0.00181%*

## Monsanto Company CR240-13E3 Page 127 of 166 Other Ingredients:

CP4 EPSPS protein (5-enolpyr uvylshikimate-3-phosphate synthase) and the genetic material necessary for its production (vect ors PV-ZMIR39 and PV-ZMIR10871) in corn events MON 88017 and MON 87411 (OECD Unique Identifier MON-88Ø17-3 and MON 87411) ....................................................................................................... ≤ 0.0069%*

Substance produced by a marker gene and it s controlling sequences in corn events TC1507 and DAS-59122-7 (PHP8999 and PS149B1) ..................................... <0.0020%**

A marker protein and the genetic material ne cessary for its production (via elements of vector pNOV1300) in corn event MIR162 (OECD Unique Identifier SYN-IR162-4).................................................................................................. ≤ 0.00073%*

*Percentage (wt/wt) on a dry weight basis whole plant (forage). **% total protein on a dry wt. basis as expressed in corn plant cells (whole plant).

CAUTION Keep Out Of Reach Of Children

## Monsanto Company CR240-13E3 Page 128 of 166 Section G. Proposed Experimental Program

G.1. Justification of the acreage requested

Monsanto Company is requesting an ame nded EUP (524-EUP-104) to test a new PIP technology, MON 87411, along with other combined tr ait insect control corn. This is an essential part of our commitment to devel op and test new PIPs and combined-trait PIP products to provide multiple modes of actio n against corn rootworm (CRW) and/or Lepidopteran corn pests. This amended EUP program is a key component to developing highly efficacious and durable PI P products to meet diverse U. S. corn growers’ needs and support multiple-dose IRM strategies (‘pyram id’) to delay development of insect resistance to PIP products.

Under this program, we ar e requesting a total of 46,522 EUP acres in aggregate across two years for MON 87411, other single- and comb ined-event corn PI P products, controls, and border corn. Of the 8,319 EUP acres requested for 2014, approximately 41% represent unregistered PIPs for evaluation (primarily PIP combinations and potential breeding intermediates), and 12,043 EUP acres requested in 2015, approximately 46% represent unregistered PIPs. The balance of the remaining acres is comprised of registered PIP materials, bor der acres, and non-PIP material s that must be accounted for

under the total EUP acres.

As outlined further in Section G below, the number of acres for unregistered PIPs is distributed among various ca ndidate PIP combinations.

Protocol 1 is for inbred and hybrid breeding a nd observation nurseries. This involves seed development and increase for future tes ting as well as nursery observations of the experimental insect-protected corn traits in various geneti c backgrounds. This involves activities such as introgression of biotech corn events into elite inbred corn lines; production of research hybrid seed for furthe r research; field data on agronomics in the presence of these traits; and collection of samples and tissues for future analysis. This entire program involves 7,219 acres of unregis tered PIPs among twenty-six test products over two years constituting ≤ 7.3% of the total requested acres.

Protocol 2 involves development and collectio n of product characterization data including Phenotypic and Agronomic Observa tions, product Efficacy and Yield Benefits, Characterization, Performance, and Regulator y data. This entire program involves 13,142 acres of unregistered PIPs among twen ty-six test products over two years, constituting 28% of the to tal requested acres.

The necessity for this program is driven by a number of important factors. Testing a

broad set of trait combinations (ideally with locally-adapted germplasm) is necessary to understand and evaluate po tential product suitability and efficacy, breeding combinability, PIP and IRM value, and the indivi dual value each trait and/or event brings to a particular event combination. A key c onsideration is the need to offer growers

biotech traits in combinations needed to m eet local insect and weed-control needs while simultaneously meeting the IRM conditions required for the individual products. Achieving this objective requires multiple pyrami ded traits for IRM durability, value, and

## Monsanto Company CR240-13E3 Page 129 of 166 appropriate spectrum of insecticidal act ivity, and must be evaluated under field conditions. Preparation and eval uation of biotech corn product s using this approach takes many years in advance in order to meet and exceed future need s. A diverse portfolio of potential options is needed in this ame nded EUP program to develop data preparing breeding stock seed for future testing needs, inbred and hybrid breeding combinability, and data for a future registration request such as efficacy, expression data, and IRM

value.

Additionally, as with any PIP EUP program , a significant portion of the acres are requested or required as controls in studies and evaluations (e.g. registered PIPs such as MON 89034 or MON 88017). Regi stered PIP, border, and non-PIP acres all contribute

to the total and account for over 56% of the 46,522 requested trial acreage total across

two years.

Finally, trial locations are not typically dete rmined until the spring of any given year. Many factors such as weather may affect the trial locations. Acreage has been requested

in consideration of such conditions. While we have projected our testing plans for 2014- 2015, it is imperative that we have flexibility to make adjustments when needed. Each

season’s new data enables the researcher to anticipate needs regarding the following year. As such, we anticipate certain combinations of events may need larger trials in the second year over the first year. In order to meet these objectives when filing an amended EUP request a year in advance, the proposed acreage accounts for contingencies in our trial plans while requesting realisti c numbers in the event the data demonstrate significant

value.

As appropriate, any inbred seed and/or hybr id seed, grain, or other plant material generated under this amended EUP will be used for future testing, planting, or will be destroyed. This is outlined in greate r detail Section G.3.g. under Final Disposition

. Monsanto certifies that none of the plantings unde r this amended EUP or any of its relevant protocols is solely for commercial incr ease. Hybrid seed (the type of seed that

could be classified as “commercial seed ”) produced under any of the amended EUP protocols will not be offered or made available for commercial sale, but will be used for future experiments, experimental planting, a nd/or evaluation. All hybrid seed and grain will ultimately be destroyed if not stored for necessary regulatory archival purposes. Inbred seed (breeding seed) that is produ ced under the amended EUP protocols will be evaluated, used to produce hybrid seed for experiments and evaluation, or destroyed, retained for future evaluation, development, and/or future breeding use. None of the seed, grain, or other plant material will be allowed to enter commerce for food or feed

purposes.

## Monsanto Company CR240-13E3 Pages 130-132 of 166 G.1.a Participants in the Experimental Program

All Participants are research scient ists employed by Monsanto Company.

Participants Supervising th e Experimental Program

Information claimed confidential has been removed to the confidential attachment. See Cross Reference 2.

## Monsanto Company CR240-13E3 Page 133 of 166 G.1.b Cooperators in the Experimental Program

The names, addresses, and telephone nu mbers of Cooperators involved in the experimental work conducted under this EUP will be provided to the Agency prior to planting.

## Monsanto Company CR240-13E3 Page 134 of 166 G.1.c Counties Where Experiment al Trials will be Conducted

Site selection for EUP trials is not typically decided until early spri ng of any given year. Many factors can affect the site selecti on process and new locations may be added throughout the duration of the EUP.

Monsanto will conduct an analysis of sel ected sites. Monsanto will not plant experimental trials within 1,320 feet of repor ted locations of thre atened or endangered lepidopteran and coleopteran spec ies (excluding extirpated or historic locations). Species presence information (county-level) will be obtained from the FIFRA Endangered Species Task Force (FESTF) Information Mana gement System (IMS). Prior to planting, species locations will be analyzed on the County and/ or Sub-County level, using the following sources:

1. U.S. Fish and Wildlife Services (USFWS) Data assembled by FESTF IMS; and

2. FESTF Multi-Jurisdictional Database (a lso known as “NatureServe location data”)

## Monsanto Company CR240-13E3 Page 135 of 166 G.2. Acreage, Seed and Active Ingredient Quantities by State or Possession

Monsanto has projected the acreage need s for the field testing program for 2014-2015. The requested Experimental Use Permit contai ns a total of 33 un-re gistered PIP and 13 registered PIP single and/or combined-tra it products, non-PIP, and border materials.

Table 1 lists the EUP test materials per un-re gistered and registered PIP subgroups. Each

individual event listed is registered by the EPA except MON 87411.

Table 1. EUP Test Materials per PIP subgroup

Un

‐ Registered PIPs

MON 89034 x MIR162 TC1507 x MIR162

MON 89034 x MON 87411 TC 1507 x MON 88017

MON 89034 X DAS

‐ 59122

‐ 7 TC1507 x MON 87411

MON 89034 x TC1507 x MIR162 TC1507 x MIR162 X MON87411

MON 89034 x TC1507 x MON 87411 TC1507 X MIR162 X DAS

‐ 59122

‐ 7

MON 89034 x MIR162 x MON 88017 TC1507 X MON88017 x DAS

‐ 59122

‐ 7

MON 89034 x MIR162 x MON 87411 TC1507 x MON 87411 x DAS

‐ 59122

‐ 7

MON 89034 X MIR162 X DAS

‐ 59122

‐ 7 TC1507 X MIR162 X MON87411 X DAS

‐ 59122

‐ 7

MON 89034 x TC1507 x MIR162 x MON 87411 MIR162 X DAS

‐ 59122

‐ 7

MON 89034 X TC1507 X MIR162 X DAS

‐ 59122

‐ 7 MIR162 X MON87411 x DAS

‐ 59122

‐ 7

MON 89034 X MON 88017 X MON 87411 MIR162 x MON 87411

MON 89034 X MON 87411 X DAS

‐ 59122

‐ 7 MON 88017 x MON 87411

MON 89034 x TC1507 x MON 87411 x DAS

‐ 59122

‐ 7 MON 88017 X MON 87411 X DAS

‐ 59122

‐ 7

MON 89034 x MIR162 x MON 88017 x DAS

‐ 59122

‐ 7 MON 87411

MON 89034 X MIR162 X MON 87411 X DAS

‐ 59122

‐ 7 MON 87411 x DAS

‐ 59122

‐ 7

MON 89034 x TC1507 x MIR162 x MON 88017 x DAS

‐ 59122

‐ 7

MON 89034 x TC1507 x MIR162 x MON 87411 x DAS

‐ 59122

‐ 7

MON 89034 x TC1507 x MON 88017 x MON 87411 x DAS

‐ 59122

‐ 7

## Monsanto Company CR240-13E3 Page 136 of 166 Table 1 (continued). EUP Test Materials per PIP subgroup

Registered PIPs

MON 89034

MON 89034 x TC1507

MON 89034 x MON 88017

MON 89034 x TC1507 x MON 88017

MON 89034 x TC1507 x DAS

‐ 59122

‐ 7

MON 89034 x MON 88017 x DAS

‐ 59122

‐ 7

MON 89034 x TC1507 x MON 88017 x DAS

‐ 59122

‐ 7

TC1507

TC1507 x DAS

‐ 59122

‐ 7

MIR162

MON 88017

MON 88017 x DAS

‐ 59122

‐ 7

DAS

‐ 59122

‐ 7



## A total of 45,522 acres are requested for th is EUP, which includes 31,869 acres of PIP materials, 7,776 acres of non-PIP materials, and 6,877 acres of border materials. The quantity of acres being requested for 2014-2015 is required to conduct field trials, using an extensive number of singl e and combined-trait products, and generate data necessary to register a combined-trait product under FIFRA.

## Monsanto Company CR240-13E3 Page 137 of 166 Table 2 lists the acres per year and EUP test material type.

Table 2. Acreage Distribution Among PI P, Non-PIP and Border Acres Over the

Duration of the EUP

Material

Type 2014 2015 Total

Acres Acres % Acres %

PIP 13558 66% 18311 70% 31869

Non

‐ PIP 3797 19% 3979 15% 7776

Border 3161 15% 3716 14% 6877

Total 20516 100% 26006 100% 46522



## Table 3 lists the acres by experimental protocol and by EUP te st material type.

Table 3. Acreage Distribution Among PIP, Non-PIP and Border Acres By Protocol

Protocol 1 (Breeding and associated data) Protocol 2 (Characterization) Total Acres (P1 + P2)



### PIP 10615 21254 31869

Non

‐ PIP 2147 5630 7776

Border 2177 4700 6877

Total 14939 31584 46522

## Monsanto Company CR240-13E3 Page 138 of 166 Table 4 provides the acreage per state for 2014-2015.

Table 4. Proposed Total Trial Acreage by State for 2014-2015

State Acres

PIP Non

‐ PIP Border Total

AL 384 34 36 454

AR 383 50 38 471

CA 32 23 8 63

CO 682 39 46 767

FL 190 10 10 210

GA 215 28 22 265

HI 5707 1333 1222 8262

IA 4276 967 856 6099

ID 2 1 1 4

IL 4100 990 857 5947

IN 1154 103 164 1421

KS 1434 598 330 2362

KY 200 14 16 230

LA 196 14 16 226

MI 385 62 95 542

MN 1854 148 322 2324

MO 564 406 319 1289

MS 705 310 231 1246

NC 188 19 14 221

ND 184 26 52 262

NE 2180 733 565 3478

OH 479 67 120 666

OK 24 18 10 52

PA 19 20 8 47

PR 2700 943 735 4378

SC 180 10 10 200

SD 1292 335 302 1929

TN 634 300 218 1152

TX 161 41 28 230

WA 353 59 94 506

WI 1018 76 132 1226

Total 31869 7776 6877 46522

## Monsanto Company CR240-13E3 Page 139 of 166 Tables 5-6 provide the proposed acreage fo r 2014-2015 per PIP combination and state for Protocol 1 and Protocol 2, re spectively. The protocols ar e listed by number code as

follows:

Protocol 1: Inbred and Hybrid Breeding and Observation Nurseries

Protocol 2: Produc t Characterization

The acreage for PIP test materials includes acrea ge for each individual PIP test material. The acreage for non-PIP materials includes acreage for any non-PIP breeding materials and any non-intentional recipients of PIP test materials within the experimental trial. The acreage for border materials includes acreage inte ntionally planted as border adjacent to trial (if applicable).

The allocation of these acres between corn materials and protocol s represents best estimates as of this date. Weather events, pest infestation levels, and other factors may

necessitate a reallocation of acres between protocols and traits.

Table 7 provides the amount of seed (in pounds) expected to be planted in states over the

duration of the EUP.

Table 7 provides the amount of active ingredient per state to be used in the EUP program. Calculation of active ingredient for each prot ein is based on an expression level of the protein(s) in corn seed on a dry weight basi s and/or DvSnf7 dsRNA. The calculations to determine the amount of active ingredient (lbs ) in each PIP test material was performed using an estimated planting density of 75,000 kernels (~47 lbs.) per acre.

Table 8 provides the pounds of seed used to calculate the active i ngredient in Table 7.Monsanto Company CR240-13E3 Page 140 of 166Table 5. Proposed Acreage for 2013-2014 per State/Territory for P1–Inbred and Hybrid Breeding and Obs. NurseriesMaterial AL AR CA CO GA HI IA ID IL IN KS KY LA MI MN

Registered PIPsDAS-59122-7 0 0 0 0 0 246 26 0 26 0 0 0 0 0 15MIR162 0 0 2 0 0 246 26 0 26 0 0 0 0 0 15MON 88017 0 0 0 0 0 106 16 0 16 0 0 0 0 0 5MON 88017 × DAS-59122-7 0 0 0 0 0 136 16 0 16 0 0 0 0 0 5MON 89034 0 0 0 0 0 266 26 0 26 0 0 0 0 0 15MON 89034 × MON 88017 0 0 4 0 0 86 16 0 16 0 0 0 0 0 5MON 89034 × MON 88017 × DAS-59122-7 0 0 0 0 0 26 13 0 13 0 0 0 0 0 1MON 89034 × TC1507 0 0 0 0 0 236 21 0 21 0 0 0 0 0 10MON 89034 × TC1507 × DAS-59122-7 0 0 0 0 0 56 13 0 13 0 0 0 0 0 1MON 89034 × TC1507 × MON 88017 0 0 0 0 0 56 16 0 16 0 0 0 0 0 5MON 89034 × TC1507 × MON 88017 × DAS59122-7 0 0 0 0 0 86 16 0 16 0 0 0 0 0 5TC1507 0 0 0 0 0 246 26 0 26 0 0 0 0 0 15TC1507 × DAS-59122-7 0 0 0 0 0 86 16 0 16 0 0 0 0 0 5Registered PIPs Total 0 0 6 00 1878 244 0 2440 0 0 0 0 102Monsanto Company CR240-13E3 Page 141 of 166Table 5 (continued). Proposed Acreage for 2013-2014 per State/Territory for P1–Inbred and Hybrid Breeding and Obs.NurseriesMaterial MO MS NC ND NE OH OK PA PR SC SD TN TX WA WITotalperPIP

Registered PIPsDAS-59122-7 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 390MIR162 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 392MON 88017 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 220MON 88017 × DAS-59122-7 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 250MON 89034 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 410MON 89034 × MON 88017 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 204MON 89034 × MON 88017 × DAS-59122-7 2 0 0 0 9 0 0 0 26 0 0 0 0 0 0 90MON 89034 × TC1507 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 365MON 89034 × TC1507 × DAS-59122-7 2 0 0 0 9 0 0 0 56 0 0 0 0 0 0 150MON 89034 × TC1507 × MON 88017 2 0 0 0 9 0 0 0 36 0 0 0 0 0 0 140MON 89034 × TC1507 ×MON 88017 × DAS-59122-7 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 200TC1507 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 390TC1507 × DAS-59122-7 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 200Registered PIPs Total 26 0 0 0117 0 0 0 778 0 0 0 0 0 0 3396Monsanto Company CR240-13E3 Page 142 of 166Table 5 (continued). Proposed Acreage for 2013-2014 per State/Territory for P1–Inbred and Hybrid Breeding and Obs.NurseriesMaterial AL AR CA CO GA HI IA ID IL IN KS KY LA MI MN

Un-Registered PIPsMIR162 × MON87411 × DAS-59122-7 0 0 0 0 0 50 9 0 9 0 0 0 0 0 5MON 87411 × DAS-59122-7 0 0 0 0 0 812 365 0 17 0 0 0 0 0 5TC1507 × MON88017 DAS-59122-7 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1MIR162 × DAS-59122-7 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1MIR162 × MON 87411 0 0 0 0 0 86 16 0 16 0 0 0 0 0 5TC1507 × MIR162 × MON87411 0 0 0 0 0 50 9 0 9 0 0 0 0 0 5TC1507 × MIR162 0 0 0 0 0 110 9 0 9 0 0 0 0 0 5MON 87411 0 0 2 0 0 249 29 0 29 0 0 0 0 0 15MON 88017 × MON 87411 DAS-59122-7 0 0 0 0 0 100 9 0 9 0 0 0 0 0 5MON 88017 × MON 87411 0 0 0 0 0 90 9 0 9 0 0 0 0 0 5TC1507 × MON 88017 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1MON 89034 × DAS-59122-7 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1MON 89034 × MON 87411 × DAS-59122-7 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1MON 89034 × MIR162 0 0 2 0 0 551 210 0 21 0 0 0 0 0 10MON 89034 × MIR162 × DAS-59122-7 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1MON 89034 × MIR162 × MON 87411 × DAS-59122-7 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1MON 89034 × MIR162 × MON 87411 0 0 0 0 0 87 17 0 17 0 0 0 0 0 5MON 89034 × MIR162 × MON 88017 0 0 0 0 0 46 19 0 19 0 0 0 0 0 2MON 89034 × MIR162 × MON 88017 × DAS-59122-7 0 0 0 0 0 26 13 0 13 0 0 0 0 0 1MON 89034 × MON 87411 0 0 2 0 0 26 13 0 553 0 0 0 0 0 1MON 89034 × MON 88017 × MON 87411 0 0 0 0 0 2 10 0 10 0 0 0 0 0 0MON 89034 × TC1507 × MON 87411 × DAS-59122-7 0 0 0 0 0 88 18 0 18 0 0 0 0 0 5Monsanto Company CR240-13E3 Page 143 of 166Table 5 (continued). Proposed Acreage for 2013-2014 per State/Territory for P1–Inbred and Hybrid Breeding and Obs.NurseriesMaterial MO MS NC ND NE OH OK PA PR SC SD TN TX WA WITotalperPIP

Un-Registered PIPsMIR162 × MON87411 × DAS-59122-7 2 0 0 0 9 0 0 0 30 0 0 0 0 0 0 114MON 87411 × DAS-59122-7 2 0 0 0 9 0 0 0 67 0 0 0 0 0 0 1277TC1507 × MON88017 DAS-59122-7 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64MIR162 × DAS-59122-7 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64MIR162 × MON 87411 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 200TC1507 × MIR162 × MON87411 2 0 0 0 9 0 0 0 30 0 0 0 0 0 0 114TC1507 × MIR162 2 0 0 0 9 0 0 0 30 0 0 0 0 0 0 174MON 87411 2 0 0 0 9 0 0 0 69 0 0 0 0 0 0 404MON 88017 × MON 87411 DAS-59122-7 2 0 0 0 9 0 0 0 60 0 0 0 0 0 0 194MON 88017 × MON 87411 2 0 0 0 9 0 0 0 60 0 0 0 0 0 0 184TC1507 × MON 88017 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64MON 89034 × DAS-59122-7 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64MON 89034 × MON 87411 × DAS-59122-7 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64MON 89034 × MIR162 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 871MON 89034 × MIR162 × DAS-59122-7 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64MON 89034 × MIR162 × MON 87411 × DAS-59122-7 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64MON 89034 × MIR162 × MON 87411 2 0 0 0 9 0 0 0 67 0 0 0 0 0 0 204MON 89034 × MIR162 × MON 88017 4 0 0 0 18 0 0 0 46 0 0 0 0 0 0 154MON 89034 × MIR162 × MON 88017 × DAS-59122-7 2 0 0 0 9 0 0 0 26 0 0 0 0 0 0 90MON 89034 × MON 87411 2 0 0 0 9 0 0 0 26 0 0 0 0 0 0 632MON 89034 × MON 88017 × MON 87411 4 0 0 0 4 0 0 0 4 0 0 0 0 0 0 34MON 89034 × TC1507 × MON 87411 × DAS-59122-7 2 0 0 0 9 0 0 0 68 0 0 0 0 0 0 208Monsanto Company CR240-13E3 Page 144 of 166Table 5 (continued). Proposed Acreage for 2013-2014 per State/Territory for P1–Inbred and Hybrid Breeding and Obs.NurseriesMaterial AL AR CA CO GA HI IA ID IL IN KS KY LA MI MN

Un-Registered PIPsMON 89034 × TC1507 × MIR162 0 0 0 0 0 432 206 0 17 0 0 0 0 0 5MON 89034 × TC1507 × MIR162 × DAS-59122-7 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1MON 89034 × TC1507 × MIR162 × MON 87411 ×DAS-59122-7 0 0 0 0 0 88 18 0 18 0 0 0 0 0 5MON 89034 × TC1507 × MIR162 × MON 87411 0 0 0 0 0 87 18 0 17 0 0 0 0 0 5MON 89034 × TC1507 × MIR162 × MON 88017 ×DAS-59122-7 0 0 0 0 0 28 15 0 15 0 0 0 0 0 1MON 89034 × TC1507 × MON 87411 0 0 0 0 0 27 14 0 14 0 0 0 0 0 1MON 89034 × TC1507 × MON 88017 × MON87411 × DAS-59122-7 0 0 0 0 0 86 16 0 16 0 0 0 0 0 5TC1507 × MON 87411 × DAS-59122-7 0 0 0 0 0 27 14 0 14 0 0 0 0 0 1TC1507 × MIR162 × DAS-59122-7 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1TC1507 × MIR162 × DAS-59122-7 × MON87411 0 0 0 0 0 20 6 0 6 0 0 0 0 0 1TC1507 × MON 87411 0 0 0 0 0 27 14 0 14 0 0 0 0 0 1Un-Registered PIPs Total 0 0 6 0 0 3375 1127 0 940 0 0 0 0 0 108Non-PIP 0 0 2 0 0 1047 118 0 118 0 0 0 0 0 5Border 0 0 0 0 0 1011 170 0 167 0 0 0 0 0 50Total Acres001400731116590146900000265Monsanto Company CR240-13E3 Page 145 of 166Table 5 (continued). Proposed Acreage for 2013-2014 per State/Territory for P1–Inbred and Hybrid Breeding and Obs.NurseriesMaterial MO MS NC ND NE OH OK PA PR SC SD TN TX WA WITotalperPIP

Un-Registered PIPsMON 89034 × TC1507 × MIR162 2 0 0 0 9 0 0 0 67 0 0 0 0 0 0 738MON 89034 × TC1507 × MIR162 × DAS-59122-7 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64MON 89034 × TC1507 × MIR162 × MON 87411 ×DAS-59122-7 2 0 0 0 9 0 0 0 68 0 0 0 0 0 0 208MON 89034 × TC1507 × MIR162 × MON 87411 2 0 0 0 9 0 0 0 68 0 0 0 0 0 0 206MON 89034 × TC1507 × MIR162 × MON 88017 ×DAS-59122-7 2 0 0 0 9 0 0 0 28 0 0 0 0 0 0 98MON 89034 × TC1507 × MON 87411 2 0 0 0 9 0 0 0 27 0 0 0 0 0 0 94MON 89034 × TC1507 × MON 88017 × MON87411 × DAS-59122-7 2 0 0 0 9 0 0 0 66 0 0 0 0 0 0 200TC1507 × MON 87411 × DAS-59122-7 2 0 0 0 9 0 0 0 27 0 0 0 0 0 0 94TC1507 × MIR162 × DAS-59122-7 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64TC1507 × MIR162 × DAS-59122-7 × MON87411 2 0 0 0 9 0 0 0 20 0 0 0 0 0 0 64TC1507 × MON 87411 2 0 0 0 9 0 0 0 27 0 0 0 0 0 0 94Un-Registered PIPs Total 70 0 0 0 301 0 0 0 1293 0 0 0 0 0 0 7219Non-PIP 100 0 0 0 110 0 0 0 647 0 0 0 0 0 0 2147Border 100 0 0 0 165 0 0 0 514 0 0 0 0 0 0 2177Total Acres296000693000323200000014939Monsanto Company CR240-13E3 Page 146 of 166Table 6. Proposed Acreage for 2013-2014 per State/Territory for P2–Product Characterization

Registered PIPsMaterial AL AR CA CO FL GA HI IA ID IL IN KS KY LA MI MNDAS-59122-710 11 2 25 6 6 12 54 0 54 35 44 6 6 10 34MIR16214 11 2 17 6 11 17 160 0 161 42 51 10 10 20 91MON 8801710 10 0 24 6 6 12 52 0 52 34 42 6 6 10 34MON 88017 × DAS-59122-710 10 0 24 6 6 12 89 0 89 39 43 6 6 10 54MON 8903414 11 2 17 6 11 17 177 0 178 57 62 10 10 20 106MON 89034 × MON 8801710 10 0 24 6 6 12 74 0 74 34 38 6 6 10 44MON 89034 × MON 88017×DAS-59122-710 10 0 24 6 6 6 58 0 58 28 36 6 6 4 32MON 89034 × TC150714 10 0 16 6 10 12 82 0 82 31 39 10 10 14 46MON 89034 × TC1507 ×DAS-59122-710 10 0 24 6 6 6 58 0 58 28 36 6 6 4 32MON 89034 × TC1507 ×MON 8801710 10 0 24 6 6 12 44 0 44 34 38 6 6 10 36MON 89034 × TC1507 ×MON 88017 × DAS-59122-710 10 0 24 6 6 12 132 0 132 49 57 6 6 10 79TC150710 11 2 13 6 7 12 41 0 42 23 32 6 6 11 22TC1507 × DAS-59122-710 10 0 24 6 6 12 74 0 74 34 38 6 6 10 44Total Registered PIP Acres142 134 6 280 78 92 154 1093 0 1097 468 556 90 90 142 654Monsanto Company CR240-13E3 Page 147 of 166Table 6 (continued). Proposed Acreage for 2013-2014 per State/Territory for P2–Product Characterization

Registered PIPsMaterial MO MS NC ND NE OH OK PA PR SC SD TN TX WA WITotal per PIPDAS-59122-713 20 7 4 46 11 1 1 18 6 36 18 4 11 35 540MIR16218 28 7 4 76 26 2 1 23 6 39 22 10 11 27 918MON 8801712 20 6 4 44 10 0 0 18 6 36 18 2 10 34 524MON 88017 × DAS-59122-712 20 6 4 55 15 0 0 18 6 41 18 2 10 34 645MON 8903418 28 7 4 82 41 2 1 23 6 54 22 10 11 27 1029MON 89034 × MON 8801712 20 6 4 50 10 0 0 18 6 36 18 4 10 40 588MON 89034 × MON 88017 ×DAS-59122-76 14 6 4 42 4 0 0 12 6 34 12 4 4 28 466MON 89034 × TC150712 22 6 4 44 15 0 0 18 6 29 22 8 10 26 604MON 89034 × TC1507 ×DAS-59122-76 14 6 4 42 4 0 0 12 6 34 12 4 4 28 466MON 89034 × TC1507 ×MON 8801712 18 6 4 40 10 0 0 18 6 36 18 4 10 34 502MON 89034 × TC1507 ×MON 88017 × DAS-59122-712 20 6 4 69 25 0 0 18 6 51 18 4 10 34 816TC150713 19 7 4 32 11 2 1 18 6 24 18 6 11 23 434TC1507 × DAS-59122-712 20 6 4 50 10 0 0 18 6 36 18 4 10 34 582Total Registered PIP Acres158 262 80 52 670 190 5 4 232 78 486 234 66 122 402 8112Monsanto Company CR240-13E3 Page 148 of 166Table 6 (continued). Proposed Acreage for 2013-2014 per State/Territory for P2–Product Characterization

Un-Registered PIPsMaterial AL AR CA CO FL GA HI IA ID IL IN KS KY LA MI MNMIR162 × MON87411 × DAS-59122-7 4 4 0 0 0 0 12 18 0 18 10 14 0 0 10 10MON 87411 × DAS-59122-7 10 10 0 24 6 6 12 112 0 112 39 47 6 6 10 64TC1507 × MON88017 DAS-59122-7 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8MIR162 × DAS-59122-7 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8MIR162 × MON 87411 10 10 0 24 6 6 12 44 0 44 34 38 6 6 10 34TC1507 × MIR162 × MON87411 4 4 0 0 0 0 12 18 0 18 10 14 0 0 10 10TC1507 × MIR162 4 4 0 0 0 0 12 28 0 28 10 14 0 0 10 15MON 87411 10 11 2 25 6 7 12 155 0 156 50 59 6 6 11 89MON 88017 × MON 87411 DAS-59122-7 4 4 0 0 0 0 12 73 0 73 15 19 0 0 10 40MON 88017 × MON 87411 4 4 0 0 0 0 12 36 0 36 10 18 0 0 10 10TC1507 × MON 88017 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8MON 89034 × DAS-59122-7 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8MON 89034 × MON 87411 × DAS-59122-7 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8MON 89034 × MIR162 14 14 4 19 6 12 17 154 0 156 45 56 10 10 21 87MON 89034 × MIR162 × DAS-59122-7 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8MON 89034 × MIR162 ×MON 87411 × DAS-59122-7 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8MON 89034 × MIR162 × MON 87411 10 12 0 24 6 8 12 47 0 48 36 40 6 6 12 35MON 89034 × MIR162 × MON 88017 14 14 0 24 6 6 12 74 0 74 32 40 6 6 8 40MON 89034 × MIR162 × MON 88017 ×DAS-59122-7 10 10 0 24 6 6 6 50 0 50 28 32 6 6 4 32MON 89034 × MON 87411 10 10 0 24 6 6 6 58 0 58 28 36 6 6 4 32Monsanto Company CR240-13E3 Page 149 of 166Table 6 (continued). Proposed Acreage for 2013-2014 per State/Territory for P2–Product Characterization

Un-Registered PIPsMaterial MO MS NC ND NE OH OK PA PR SC SD TN TX WA WITotal per PIPMIR162 × MON87411 × DAS-59122-7 12 12 0 4 14 10 0 0 12 0 12 12 0 10 10 208MON 87411 × DAS-59122-7 12 20 6 4 64 15 0 0 18 6 41 18 4 10 29 711TC1507 × MON88017 DAS-59122-7 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148MIR162 × DAS-59122-7 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148MIR162 × MON 87411 12 20 6 4 40 10 0 0 18 6 36 18 4 10 34 502TC1507 × MIR162 × MON87411 12 12 0 4 14 10 0 0 12 0 12 12 0 10 10 208TC1507 × MIR162 12 12 0 4 14 10 0 0 12 0 12 12 0 10 10 233MON 87411 13 21 7 4 81 26 2 1 18 6 51 18 4 11 35 898MON 88017 × MON 87411 DAS-59122-7 12 12 0 4 34 15 0 0 12 0 17 12 0 10 10 388MON 88017 × MON 87411 12 12 0 4 18 10 0 0 12 0 12 12 0 10 10 252TC1507 × MON 88017 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148MON 89034 × DAS-59122-7 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148MON 89034 × MON 87411 × DAS-59122-7 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148MON 89034 × MIR162 21 29 8 4 74 27 5 4 23 6 39 22 14 13 28 942MON 89034 × MIR162 × DAS-59122-7 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148MON 89034 × MIR162 × MON 87411 ×DAS-59122-7 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148MON 89034 × MIR162 × MON 87411 14 22 6 4 40 10 3 2 18 6 36 18 6 10 34 531MON 89034 × MIR162 × MON 88017 12 20 6 8 50 8 0 0 18 6 44 18 4 8 32 590MON 89034 × MIR162 × MON 88017 ×DAS-59122-7 6 14 6 4 38 4 0 0 12 6 34 12 4 4 28 442MON 89034 × MON 87411 6 14 6 4 42 4 0 0 12 6 34 12 4 4 28 466Monsanto Company CR240-13E3 Page 150 of 166Table 6 (continued). Proposed Acreage for 2013-2014 per State/Territory for P2–Product Characterization

Un-Registered PIPsMaterial AL AR CA CO FL GA HI IA ID IL IN KS KY LA MI MNMON 89034 × MON 88017 × MON87411 0 0 0 0 0 0 2 8 0 8 0 4 0 0 0 0MON 89034 × TC1507 × MON 87411 ×DAS-59122-7 10 12 4 27 12 11 17 108 2 109 38 47 6 6 10 64MON 89034 × TC1507 × MIR162 14 14 4 19 10 12 12 104 0 106 35 46 10 6 16 57MON 89034 × TC1507 × MIR162 ×DAS-59122-7 4 4 0 0 0 0 6 32 0 32 4 12 0 0 4 8MON 89034 × TC1507 × MIR162 ×MON 87411 × DAS-59122-7 10 10 0 24 6 6 12 99 0 99 39 43 6 6 10 64MON 89034 × TC1507 × MIR162 ×MON 87411 10 12 0 24 6 8 12 55 0 56 36 44 6 6 12 35MON 89034 × TC1507 × MIR162 ×MON 88017 × DAS-59122-7 10 10 0 24 6 6 6 58 0 58 28 36 6 6 4 32MON 89034 × TC1507 × MON 87411 10 10 0 24 6 6 6 58 0 58 28 36 6 6 4 32MON 89034 × TC1507 × MON 88017 ×MON 87411 × DAS-59122-7 10 10 0 24 6 6 12 99 0 99 39 43 6 6 10 64TC1507 × MON 87411 × DAS-59122-7 10 10 0 24 6 6 6 50 0 50 28 32 6 6 4 32TC1507 × MIR162 × DAS-59122-7 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8TC1507 × MIR162 × DAS-59122-7 ×MON87411 4 4 0 0 0 0 6 24 0 24 4 8 0 0 4 8TC1507 × MON 87411 10 10 0 24 6 6 6 58 0 58 28 36 6 6 4 32Total Un-Registered PIP Acres 242 249 14402 112 124 300 1812 2 1820 686 878110 106 244 990Border 36 38 8 46 10 22 211 686 1 690 164 330 16 16 95 272Non-PIP 34 50 21 39 10 28 286 849 1 872 103 598 14 14 62 143Total45447149767210265951444044478142123622302265422059Monsanto Company CR240-13E3 Page 151 of 166Table 6 (continued). Proposed Acreage for 2013-2014 per State/Territory for P2–Product Characterization

Un-Registered PIPsMaterial MO MS NC ND NE OH OK PA PR SC SD TN TX WA WITotal per PIPMON 89034 × MON 88017 × MON87411 2 2 0 0 4 0 0 0 2 0 2 2 0 0 0 36MON 89034 × TC1507 × MON 87411× DAS-59122-7 14 20 7 4 64 17 1 2 18 6 41 18 7 12 36 750MON 89034 × TC1507 × MIR162 16 24 8 4 54 17 5 4 18 6 29 22 14 13 28 727MON 89034 × TC1507 × MIR162 ×DAS-59122-7 6 6 0 4 16 4 0 0 6 0 10 6 0 4 4 172MON 89034 × TC1507 × MIR162 ×MON 87411 × DAS-59122-7 12 20 6 4 55 15 0 0 18 6 41 18 4 10 34 677MON 89034 × TC1507 × MIR162 ×MON 87411 14 22 6 4 44 10 3 2 18 6 36 18 6 10 34 555MON 89034 × TC1507 × MIR162 ×MON 88017 × DAS-59122-7 6 14 6 4 42 4 0 0 12 6 34 12 4 4 28 466MON 89034 × TC1507 × MON 87411 6 14 6 4 42 4 0 0 12 6 34 12 4 4 28 466MON 89034 × TC1507 × MON 88017× MON 87411 × DAS-59122-7 12 20 6 4 60 15 0 0 18 6 41 18 4 10 34 682TC1507 × MON 87411 × DAS59122-7 6 14 6 4 38 4 0 0 12 6 34 12 4 4 28 442TC1507 × MIR162 × DAS-59122-7 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148TC1507 × MIR162 × DAS-59122-7 ×MON87411 6 6 0 4 12 4 0 0 6 0 10 6 0 4 4 148TC1507 × MON 87411 6 14 6 4 42 4 0 0 12 6 34 12 4 4 28 466Total Un-Registered PIP Acres 310 444 108 132 1092 289 19 15 397 102806 400 95 231 616 13142Border 219 231 14 52 400 120 10 8 221 10 302 218 28 94 132 4700Non-PIP 306 310 19 26 623 67 18 20 296 10 335 300 41 59 76 5630Total993124622126227856665247114620019291152230506122631584Monsanto Company CR240-13E3 Page 152 of 166Table 7. Amount of Seed (pounds) Expected to bePlanted in States Over the Duration of the EUP

AL AR CA CO FL GA HI IA ID IL IN KS KY LA MI MNBorder 1,692 1,786 376 2,162 470 1,034 57,43440,241 47 40,288 7,708 15,510 752 752 4,465 15,115DAS-59122-7 470 494 71 1,175 282 282 12,126 3,7270 3,751 1,622 2,045 282 282 470 2,303MIR162 × MON87411 × DAS-59122-7 188 188 0 0 0 0 2,914 1,269 0 1,269 470 658 0 0 470 705MON 87411 × DAS-59122-7 470 470 0 1,128 282 282 38,72822,410 0 6,054 1,833 2,209 282 282 470 3,243TC1507 × MON88017 × DAS-59122-7 188 188 0 0 0 0 1,222 1,410 0 1,410 188 376 0 0 188 423MIR162 658 517 165 799 282 494 12,361 8,709 0 8,756 1,974 2,397 470 470 917 4,982MIR162 × DAS-59122-7 188 188 0 0 0 0 1,222 1,410 0 1,410 188 376 0 0 188 423MIR162 × MON 87411 470 470 0 1,128 282 282 4,6062,811 0 2,811 1,598 1,786 282 282 470 1,833TC1507 × MIR162 × MON87411 188 188 0 0 0 0 2,914 1,269 0 1,269 470 658 0 0 470 705TC1507 × MIR162 188 188 0 0 0 0 5,734 1,739 0 1,739 470 658 0 0 470 940MON 87411 470 517 165 1,175 282 306 12,267 8,6150 8,662 2,350 2,773 282 282 494 4,888MON 88017 470 470 0 1,128 282 282 5,546 3,1870 3,187 1,598 1,974 282 282 470 1,833MON 88017 × DAS-59122-7 470 470 0 1,128 282 282 6,9564,926 0 4,926 1,833 2,021 282 282 470 2,773MON 88017 × MON 87411 × DAS-59122-7 188 188 0 0 0 0 5,264 3,854 0 3,854 705 893 0 0 470 2,115MON 88017 × MON 87411 188 188 0 0 0 0 4,794 2,115 0 2,115 470 846 0 0 470 705TC 1507 × MON 88017 188 188 0 0 0 0 1,222 1,410 0 1,410 188 376 0 0 188 423MON 89034 658 517 71 799 282 494 13,301 9,508 0 9,555 2,679 2,914 470 470 917 5,687MON 89034 × DAS-59122-7 188 188 0 0 0 0 1,222 1,410 0 1,410 188 376 0 0 188 423MON 89034 × MON 87411 × DAS-59122-7 188 188 0 0 0 0 1,222 1,410 0 1,410 188 376 0 0 188 423MON 89034 × MIR162 658 658 282 893 282 564 26,696 17,099 0 8,310 2,115 2,632 470 470 987 4,559MON 89034 × MIR162 × DAS-59122-7 188 188 0 0 0 0 1,222 1,410 0 1,410 188 376 0 0 188 423MON 89034 × MIR162 ×MON 87411 × DAS-59122-7 188 188 0 0 0 0 1,222 1,410 0 1,410 188 376 0 0 188 423MON 89034 × MIR162 × MON 87411 470 564 0 1,128 282 376 4,653 2,999 0 3,046 1,692 1,880 282 282 564 1,880MON 89034 × MIR162 × MON 88017 658 658 0 1,128 282 282 2,726 4,362 0 4,362 1,504 1,880 282 282 376 1,974MON 89034 × MIR162 ×MON 88017 × DAS-59122-7 470 470 0 1,128 282 282 1,5042,952 0 2,952 1,316 1,504 282 282 188 1,551MON 89034 × MON 87411 470 470 94 1,128 282 282 1,504 3,328 0 28,708 1,316 1,692 282 282 188 1,551MON 89034 × MON 88017 470 470 188 1,128 282 282 4,606 4,221 0 4,221 1,598 1,786 282 282 470 2,303Monsanto Company CR240-13E3 Page 153 of 166Table 7 (continued). Amount of Seed (pounds) Expected tobe Planted in States Over the Duration of the EUP

MO MS NC ND NE OH OK PA PR SC SD TN TX WA WITotal per PIPBorder 14,993 10,857 658 2,444 26,555 5,640 470 37634,545 470 14,194 10,246 1,316 4,418 6,204 323,219DAS-59122-7 682 940 306 188 2,562 494 24 24 3,948 282 1,692 846 165 517 1,622 43,668MIR162 × MON87411 × DAS-59122-7 658 564 0 188 1,081 470 0 0 1,974 0 564 564 0 470 470 15,134MON 87411 × DAS-59122-7 658 940 282 188 3,431 705 0 0 3,995 282 1,927 846 188 470 1,363 93,417TC1507 × MON88017 × DAS-59122-7 376 282 0 188 987 188 0 0 1,222 0 470 282 0 188 188 9,964MIR162 940 1,293 306 188 3,972 1,199 71 47 4,183 282 1,833 1,034 470 517 1,246 61,528MIR162 × DAS-59122-7 376 282 0 188 987 188 0 0 1,222 0 470 282 0 188 188 9,964MIR162 × MON 87411 658 940 282 188 2,303 470 0 0 3,948 282 1,692 846 188 470 1,598 32,975TC1507 × MIR162 × MON87411 658 564 0 188 1,081 470 0 0 1,974 0 564 564 0 470 470 15,134TC1507 × MIR162 658 564 0 188 1,081 470 0 0 1,974 0 564 564 0 470 470 19,129MON 87411 705 964 306 188 4,207 1,199 71 47 4,089 282 2,397 846 188 517 1,622 61,152MON 88017 658 940 282 188 2,491 470 0 0 3,948 282 1,692 846 94 470 1,598 34,949MON 88017 × DAS-59122-7 658 940 282 188 3,008 705 0 0 3,948 282 1,927 846 94 470 1,598 42,046MON 88017 × MON 87411 × DAS-59122-7 658 564 0 188 2,021 705 0 0 3,384 0 799 564 0 470 470 27,354MON 88017 × MON 87411 658 564 0 188 1,269 470 0 0 3,384 0 564 564 0 470 470 20,492TC 1507 × MON 88017 376 282 0 188 987 188 0 0 1,222 0 470 282 0 188 188 9,964MON 89034 940 1,293 306 188 4,254 1,904 71 47 4,183 282 2,538 1,034 470 517 1,246 67,591MON 89034 × DAS-59122-7 376 282 0 188 987 188 0 0 1,222 0 470 282 0 188 188 9,964MON 89034 × MON 87411 × DAS-59122-7 376 282 0 188 987 188 0 0 1,222 0 470 282 0 188 188 9,964MON 89034 × MIR162 1,081 1,363 376 188 3,901 1,269235 188 4,183 282 1,833 1,034 658 611 1,316 85,192MON 89034 × MIR162 × DAS-59122-7 376 282 0 188 987 188 0 0 1,222 0 470 282 0 188 188 9,964MON 89034 × MIR162 ×MON 87411 × DAS-59122-7 376 282 0 188 987 188 0 0 1,222 0 470 282 0 188 188 9,964MON 89034 × MIR162 × MON 87411 752 1,034 282 188 2,303 470 141 94 3,995 282 1,692 846 282 470 1,598 34,526MON 89034 × MIR162 × MON 88017 752 940 282 376 3,196 376 0 0 3,008 282 2,068 846 188 376 1,504 34,949MON 89034 × MIR162 ×MON 88017 × DAS-59122-7 376 658 282 188 2,209 188 0 0 1,786 282 1,598 564 188 188 1,316 24,985MON 89034 × MON 87411 376 658 282 188 2,397 188 0 0 1,786 282 1,598 564 188 188 1,316 51,587MON 89034 × MON 88017 658 940 282 188 2,773 470 0 0 3,948 282 1,692 846 188 470 1,880 37,205Monsanto Company CR240-13E3 Page 154 of 166Table 7 (continued). Amount of Seed (pounds) Expected tobe Planted in States Over the Duration of the EUP

AL AR CA CO FL GA HI IA ID IL INMON 89034 × MON 88017 × DAS-59122-7470 470 0 1,128 282 282 1,504 3,328 0 3,328 1,316MON 89034 × MON 88017 × MON 874110 0 0 0 0 0 188 846 0 846 0MON 89034 × TC1507658 470 0 752 282 470 11,656 4,832 0 4,832 1,457MON 89034 × TC1507 × DAS-59122-7470 470 0 1,128 282 282 2,914 3,328 0 3,328 1,316MON 89034 × TC1507 × MON 87411 × DAS-59122-7470 564 188 1,269 564 517 4,935 5,913 94 5,960 1,786MON 89034 × TC1507 × MIR162658 658 188 893 470 564 20,868 14,561 0 5,772 1,645MON 89034 × TC1507 × MIR162 × DAS-59122-7188 188 0 0 0 0 1,222 1,786 0 1,786 188MON 89034 × TC1507 × MIR162 ×MON 87411 × DAS-59122-7470 470 0 1,128 282 282 4,700 5,490 0 5,490 1,833MON 89034 × TC1507 × MIR162 × MON 87411470 564 0 1,128 282 376 4,653 3,422 0 3,422 1,692MON 89034 × TC1507 × MIR162 ×MON 88017 × DAS-59122-7470 470 0 1,128 282 282 1,598 3,422 0 3,422 1,316MON 89034 × TC1507 × MON 87411470 470 0 1,128 282 282 1,551 3,375 0 3,375 1,316MON 89034 × TC1507 × MON 88017470 470 0 1,128 282 282 3,196 2,811 0 2,811 1,598MON 89034 × TC1507 × MON 88017 × DAS-59122-7470 470 0 1,128 282 282 4,606 6,947 0 6,947 2,303MON 89034 × TC1507 × MON 88017 ×MON 87411 × DAS-59122-7470 470 0 1,128 282 282 4,606 5,396 0 5,396 1,833Non-PIP1,598 2,350 1,081 1,833 470 1,316 62,651 45,440 47 46,521 4,841TC1507470 517 71 611 282 306 12,126 3,116 0 3,163 1,081TC1507 × DAS-59122-7470 470 0 1,128 282 282 4,606 4,221 0 4,221 1,598TC1507 × MON 87411 × DAS-59122-7470 470 0 1,128 282 282 1,551 2,999 0 2,999 1,316TC1507 × MIR162 × DAS-59122-7188 188 0 0 0 0 1,222 1,410 0 1,410 188TC1507 × MIR162 × MON87411 × DAS-59122-7188 188 0 0 0 0 1,222 1,410 0 1,410 188TC1507 × MON 87411470 470 0 1,128 282 282 1,551 3,375 0 3,375 1,316Total21,338 22,114 2,938 36,049 9,870 12,455 388,314 286,630 188 279,509 66,764Monsanto Company CR240-13E3 Page 155 of 166Table 7 (continued). Amount of Seed (pounds) Expected tobe Planted in States Over the Duration of the EUP

KS KY LA MI MN MO MS NC ND NE OHMON 89034 × MON 88017 × DAS-59122-71,692 282 282 188 1,551 376 658 282 188 2,397 188MON 89034 × MON 88017 × MON 87411188 0 0 0 0 282 94 0 0 376 0MON 89034 × TC15071,833 470 470 658 2,632 658 1,034 282 188 2,491 705MON 89034 × TC1507 × DAS-59122-71,692 282 282 188 1,551 376 658 282 188 2,397 188MON 89034 × TC1507 × MON 87411 × DAS-59122-72,209 282 282 470 3,243 752 940 329 188 3,431 799MON 89034 × TC1507 × MIR1622,162 470 282 752 2,914 846 1,128 376 188 2,961 799MON 89034 × TC1507 × MIR162 × DAS-59122-7564 0 0 188 423 376 282 0 188 1,175 188MON 89034 × TC1507 × MIR162 ×MON 87411 × DAS-59122-72,021 282 282 470 3,243 658 940 282 188 3,008 705MON 89034 × TC1507 × MIR162 × MON 874112,068 282 282 564 1,880 752 1,034 282 188 2,491 470MON 89034 × TC1507 × MIR162 ×MON 88017 × DAS-59122-71,692 282 282 188 1,551 376 658 282 188 2,397 188MON 89034 × TC1507 × MON 874111,692 282 282 188 1,551 376 658 282 188 2,397 188MON 89034 × TC1507 × MON 880171,786 282 282 470 1,927 658 846 282 188 2,303 470MON 89034 × TC1507 × MON 88017 × DAS-59122-72,679 282 282 470 3,948 658 940 282 188 3,666 1,175MON 89034 × TC1507 × MON 88017 ×MON 87411 × DAS-59122-72,021 282 282 470 3,243 658 940 282 188 3,243 705Non-PIP28,106 658 658 2,891 6,956 19,082 14,570 893 1,222 34,451 3,149TC15071,504 282 282 494 1,739 705 870 306 188 1,904 494TC1507 × DAS-59122-71,786 282 282 470 2,303 658 940 282 188 2,773 470TC1507 × MON 87411 × DAS-59122-71,504 282 282 188 1,551 376 658 282 188 2,209 188TC1507 × MIR162 × DAS-59122-7376 0 0 188 423 376 282 0 188 987 188TC1507 × MIR162 × MON87411 × DAS-59122-7376 0 0 188 423 376 282 0 188 987 188TC1507 × MON 874111,692 282 282 188 1,551 376 658 282 188 2,397 188Total110,991 10,810 10,622 25,451 109,209 60,560 58,562 10,364 12,314 163,443 31,279Monsanto Company CR240-13E3 Page 156 of 166Table 7 (continued). Amount of Seed (pounds) Expected tobe Planted in States Over the Duration of the EUP

OK PA PR SC SD TN TX WA WITotal per PIPMON 89034 × MON 88017 × DAS-59122-70 0 1,786 282 1,598 564 188 188 1,316 26,113MON 89034 × MON 88017 × MON 874110 0 282 0 94 94 0 0 0 3,290MON 89034 × TC15070 0 3,948 282 1,363 1,034 376 470 1,222 45,524MON 89034 × TC1507 × DAS-59122-70 0 3,196 282 1,598 564 188 188 1,316 28,933MON 89034 × TC1507 × MON 87411 × DAS-59122-747 94 4,042 282 1,927 846 329 564 1,692 45,007MON 89034 × TC1507 × MIR162235 188 3,995 282 1,363 1,034 658 611 1,316 68,836MON 89034 × TC1507 × MIR162 × DAS-59122-70 0 1,222 0 470 282 0 188 188 11,092MON 89034 × TC1507 × MIR162 ×MON 87411 × DAS-59122-70 0 4,042 282 1,927 846 188 470 1,598 41,576MON 89034 × TC1507 × MIR162 × MON 87411141 94 4,042 282 1,692 846 282 470 1,598 35,748MON 89034 × TC1507 × MIR162 ×MON 88017 × DAS-59122-70 0 1,880 282 1,598 564 188 188 1,316 26,489MON 89034 × TC1507 × MON 874110 0 1,833 282 1,598 564 188 188 1,316 26,301MON 89034 × TC1507 × MON 880170 0 2,538 282 1,692 846 188 470 1,598 30,155MON 89034 × TC1507 × MON 88017 × DAS-59122-70 0 3,948 282 2,397 846 188 470 1,598 47,733MON 89034 × TC1507 × MON 88017 ×MON 87411 × DAS-59122-70 0 3,948 282 1,927 846 188 470 1,598 41,435Non-PIP846 940 44,321 470 15,745 14,100 1,927 2,773 3,572 365,477TC150771 47 3,948 282 1,128 846 282 517 1,058 38,686TC1507 × DAS-59122-70 0 3,948 282 1,692 846 188 470 1,598 36,735TC1507 × MON 87411 × DAS-59122-70 0 1,833 282 1,598 564 188 188 1,316 25,173TC1507 × MIR162 × DAS-59122-70 0 1,222 0 470 282 0 188 188 9,964TC1507 × MIR162 × MON87411 × DAS-59122-70 0 1,222 0 470 282 0 188 188 9,964TC1507 × MON 874110 0 1,833 282 1,598 564 188 188 1,316 26,301Total2,421 2,186 205,766 9,400 90,663 54,144 10,787 23,782 57,599 2,186,515Monsanto Company CR240-13E3 Page 157 of 166Table 8. Proposed Amount of PIP Active Ingredient(grams) Over the Duration of the EUP for Each StateCry1F Cry1A.105Cry2Ab2 Vip3Aa20Dv49 dsRNA Cry3Bb1Cry34Ab1 Cry35Ab1AL29.37 32.4915.33 130.715.37E-05 78.01349.00 8.54AR29.53 32.5214.83 131.575.62E-05 78.83354.02 8.66CA1.50 3.250.95 11.613.45E-06 2.6511.03 0.27CO53.53 61.1429.48 191.761.06E-04 157.28633.82 15.51FL15.79 17.518.30 55.032.83E-05 39.91168.48 4.12GA16.97 20.249.63 69.222.96E-05 40.32166.48 4.07HI335.54 388.08173.08 1889.258.11E-04 772.164673.45 114.35IA280.99 351.12153.71 1444.246.46E-04 754.313979.25 97.36ID0.32 0.300.09 0.007.25E-07 0.234.01 0.10IL251.77 376.37161.29 1124.357.17E-04 967.323284.25 80.36IN84.95 97.5147.27 351.711.74E-04 247.521027.96 25.15KS106.58 120.2057.65 447.162.15E-04 304.141288.71 31.53KY15.47 18.239.03 61.912.61E-05 39.20156.45 3.83LA14.84 17.638.85 58.472.61E-05 39.20156.45 3.83MI27.24 29.2513.59 146.625.53E-05 70.28312.90 7.66MN129.64 152.5572.93 571.852.71E-04 367.951650.75 40.39Monsanto Company CR240-13E3 Page 158 of 166Table 8 (continued). Proposed Amount ofPIP Active Ingredient (grams) Over the Duration of the EUP for Each StateCry1F Cry1A.105Cry2Ab2 Vip3Aa20Dv49 dsRNA Cry3Bb1Cry34Ab1 Cry35Ab1MO40.58 43.1719.28 208.968.60E-05 112.91510.47 12.49MS51.87 56.7226.39 244.651.05E-04 142.02617.78 15.12NC14.76 16.848.09 55.462.67E-05 39.38159.46 3.90ND13.90 14.266.31 68.792.76E-05 38.81192.55 4.71NE159.09 180.0583.30 696.973.29E-04 462.342087.01 51.07OH32.29 37.0417.99 158.666.91E-05 90.53408.17 9.99OK1.66 2.760.83 15.053.08E-06 1.003.01 0.07PA1.42 2.240.67 11.182.54E-06 0.825.01 0.12PR198.32 206.8794.89 884.004.17E-04 550.322503.20 61.25SC14.21 16.027.85 51.602.61E-05 39.20156.45 3.83SD96.00 108.5351.59 399.001.97E-04 285.811237.56 30.28TN47.69 49.9323.85 216.709.43E-05 129.53565.63 13.84TX12.79 16.027.35 60.192.00E-05 24.91105.30 2.58WA26.21 25.6211.99 126.415.48E-05 70.11318.92 7.80WI78.40 85.8541.15 310.001.57E-04 227.51933.69 22.85Total AI (grams)2184.80 2580.30 1177.52 10193.08 4.84E-03 6175.68 28021.24 685.63

## Monsanto Company CR240-13E3 Page 159 of 166 G.3 EUP Program Details

G.3.a. Crop: Corn ( Zea mays L.)

G.3.b. Target Pests: Lepidopteran and Coleopteran insect pests

G.3.c. Major Geographic Areas: EUP trials may occur in 30 states and Puerto Rico, representing diverse agronomic zones. Shipment (to/from) may occur in the United States and

Puerto Rico.

G.3.d. Sites: Research stations, seed production fields, privately owned farms, and university farms.

G.3.e. Period of Use: Plantings from February 15, 2014 through February 28, 2016.

G.3.f. Protocols for EUP Trials: Research trials planned under the EUP Program will be conducted unde r the following two protocols:

1. Protocol 1 - Inbred and Hybrid Breeding and Observation Nurseries

 Seed development and increase for future testing

 Nursery observations of traits in various genetic backgrounds

2. Protocol 2 - Product Characterization

 Phenotypic and Agronomic Observations

 Efficacy and Yield Benefits

 Product Characterization, Perf ormance, and Regulatory

## Monsanto Company CR240-13E3 Page 160 of 166 G.3.f.1 Protocol 1 - Inbred and Hybr id Breeding and Observation Nurseries

 Seed development and increase for future testing

 Nursery observations of traits in various genetic backgrounds

Objective

 Introgress biotech corn events into elite inbred corn lines.

 Produce research hybrid seed for evaluation in field, greenhouse, and/ or laboratory trials.

 Collect phenotypic data on converted inbred lines.

 Collect plant tissue on converted inbr ed lines for laboratory analysis.

 Seed is generally retained for future breeding or testing purposes.

Description EUP Trials will generally be plan ted in a randomized block design or single large blocks. Plants may be hand- or open-pollinated with conven tional or other biotechnology-derived corn. The corn may be self-pollinated, backcrossed, or othe rwise crossed to other PIP or non-PIP plants. Seeds and/or plants may be treated with herbic ides, plant growth regulators, fungicides and/or insecticides. Samples may be collected for an alyses to determine phenotype, genotype, and/or other research purposes.

Genotypes and Vectors The PIP test material will consist of insect-p rotected corn in differe nt genetic backgrounds.

Containment EUP Trials will be managed consistent with the containment procedures outlined in Section G.3.h., titled EUP Design Protocol.

## Monsanto Company CR240-13E3 Page 161 of 166 G.3.f.2 Protocol 2 - Product Characterization

 Phenotypic and Agronomic Observations

 Efficacy and Yield Benefits

 Product Characterization, Perf ormance, and Regulatory

Objective

 Assess agronomic effects of the genetic insertion and combina tions of biotech corn event in various genetic backgrounds under variou s environmental and insect pressure

conditions.

 Assess the yield and agronomic properties of EUP test inbreds and hybrids compared to other single and stacked event inbreds and hyb rids (both registered and non-registered PIP single events and breeding stacks), co mmercial check hybrids (registered PIPs), conventional hybrids, and/or insecticide treatments.

 Assess the herbicide tolerance of EUP test ma terials (including EUP test materials that

have been crossed with non-PIP he rbicide tolerant lines of corn).

 Assess efficacy in various genetic backgr ounds against lepidopter an, coleopteran, and other potential pests of corn. Develop data to assess the benefits of PIP test materials in

various combinations.

 Develop data to assess the benefits of MON 87411 and MIR162 alone and/or in

combination with other test materials.

 Produce grain and plant material for product ch aracterization and perf ormance studies.

 Assess the level of control that PIP test pl ants provide of key le pidopteran, coleopteran, and other potential pests of cor n. Develop data to assess the be nefits of PIP test materials

in various combinations.

 Conduct field trials as needed to s upport global regulatory submissions.

 Generate plant tissue samples from EUP test plants for use in regulatory and/or other

research characterization studies.

 Collect phenotypic data for use in global regulatory submissions.

 To develop data to fulfill the requiremen ts for Section 3 product registration under

FIFRA.

 Trials are generally terminal, whereas the s eed may be disposed using approved methods outlined in Final Disposition.

Description EUP Trials will generally be planted in a randomized block design or single large blocks. Seeds and/or plants may be treated with herbicides , plant growth regulators, fungicides and/or

insecticides.

Phenotypic and Agronomic Observations EUP Trials will be evaluated for several phenot ypic and agronomic characteristics, such as seedling germination, seedling emergence, early vigor, plant color, pl ant height, days to flowering, days to maturity, yiel d and test weight. EUP trials may be assessed for herbicide tolerance and/or disease resistance resulting from genetic insertion and combinations of biotech corn events in various genetic backgrounds.

## Monsanto Company CR240-13E3 Page 162 of 166 Efficacy and Yield Benefits EUP Trials may be evaluated for efficacy agains t lepidopteran, coleopteran and other corn pests and/or for yield. Artificial or na tural infestations of lepidopteran and coleopteran may be used in these trials. Ears from EUP plants may be assessed for insect damage and mold incidence. Trials may include and/or be compared to non-transgenic or transgenic corn. Commercial checks may be planted as comparators.

Product Characterization, Performance, and Regulatory EUP trials may be evaluated for phenotypic/ag ronomic characteristics and plant tissue samples may be collected at various developmental growth stages for generating the basic

characterization data includi ng (but not limited to) compos ition, protein expression, and agronomic/phenotypic assessments.

Data will be collected for the development of insect resistance management (IRM) strategies and to determine the level of control of lepidopteran , coleopteran, and other corn pests provided by the PIP test plants. Testing may include rating le vels of damage and mortality for the relevant species in naturally an d artificially infested trials. Tr ials may include non-transgenic or transgenic corn.

Genotypes and Vectors The PIP test material will consist of insect-p rotected corn in differe nt genetic backgrounds.

Containment EUP Trials will be managed consistent with the containment procedures outlined in Section G.3.h., titled EUP Design Protocol.

## Monsanto Company CR240-13E3 Page 163 of 166 G.3.g. EUP Design Protocol

Seed generated under this EUP will not be offered fo r commercial sale or o ffered for use as food

or feed.

The following containment procedures will be used for all EUP Trials.

Schedule

 Hawaii and Puerto Rico plantings are c ontinuous, but include a minimum 30-day irrigated fallow period after ea ch harvest. In Puerto Rico, rainfall may substitute for irrigation.

 The U.S. (excluding Hawaii) may have up to four plantings per site. Trials are generally planted February through July and harvested August through November.

Storage of EUP Material

 EUP test seed will be stored in a secure location and handled in a manner to prevent

unintended release into the environment.

 To prevent accidental mixing of EUP-re gulated and non-EUP material, a uniform identification scheme should be implemented. Examples of identification include (but are not limited to) color coding, marking, tagg ing, or otherwise dis tinguishing seed to allow easy recognition.

Shipment (Movement) of Regu lated Plant Material

 Packing Regulated Material – EUP test seed will be tr ansported in secured, closed

containers of such construction to avoid loss of seed outside the container during transport. The EPA stamped master label and a Monsanto EUP shipment summary label (see example) will be included with shipments of viable plant material (corn seed, whole plants, seedlings, immature embryos, pollen and cobs). Non-viable plant material (leaf tissue and roots) may be shipped without a label.

 Labeling the Shipping Container – When shipping, the shipping container must be labeled with the crop, the EUP number, address, and number of containers.

## Monsanto Company CR240-13E3 Page 164 of 166 Example: Monsanto EUP Shipment Summary Label



# Monsanto EUP Shipment Summary Label

524-EUP-104

Event Net contents (lbs)

MON 87411 1.0

MIR162 5.0

MON 89034 x MIR162 6.5

Non-PIP 2.5

Border 10

Planting

 Trials will be planted at locations speci fied in USDA notifications or permits (if applicable), in states approved by the EP A Experimental Use Permit (EUP), and in locations approved according to EUP Secti on G.1.c. (See “Counties Where Experimental Trials will be Conducted”).

 EUP trials will generally be planted in a random ized block design or single large blocks.

 After planting is completed and before the planter leaves the field, the planter will be thoroughly cleaned out to prevent mixing with other corn seed. Seed will be disposed according to approved disposition methods (see “Final Disposition”).

Isolation (Pollen Containment)

 PIP test materials will be isolated to preven t persistence in the environment. Isolation methods will be implemented consistent with USDA Performance Standards at 7 CFR § 340.3(c).

Sampling

 Plant tissue, seed, and/or whole plant sa mples may be collected during the growing season and shipped to Monsanto facilities and/ or third party facili ties for analysis.

Harvest Procedures

 Plots may be harvested by hand or mechanically.

 EUP test material may be harveste d for further res earch purposes.

 Harvested ears, seed, or grain will be placed in labeled containers of such construction to prevent loss of plant material.

 Equipment will be thoroughly clea ned after harvesting operations.

## Monsanto Company CR240-13E3 Page 165 of 166 Final Disposition

 Containers

o May be inspected and cleared of remnant seed for reuse; or

o Destroyed by burning, incinera tion, dry or steam heat, co mposting or buried in the test field, and/or shippe d to approved outside pro cessor for destruction

 Leftover planting seed and harvested s eed, grain, or plant material may be:

o Used for other research purposes; or

o Used as future planting seed; or

o Returned to a secure on-site storage location; or

o Returned to Monsanto faciliti es or third party facilities; or

o Destroyed by dry or steam heat, burning or incineration, physical grinding, chemical application, composting or buryi ng in the test field, or shipping to approved outside processor for destruction

 Non-harvested plots (including border) and volunteer monitoring

o Plant material and/or seed from non-ha rvested plots (includi ng border) will be

devitalized. Devitalization methods include (but are not limited to) hand weeding, grinding, burning or incineration, chemical application, or mechanical

cultivation.

o Volunteer plants will be routinely monitored and de stroyed by hand weeding, grinding, burning or incineration, chemical application, or mechanical cultivation.

Crop Rotation

 Options for replanting the trial s ite the following growing season:

o Leave the site fallow and control any volunteer plants.

o Plant to another appropriate rotationa l crop that would allow the clear

identification and control of volunteer corn plants. Replanting to corn not regulated by EPA or USDA is NOT allowed.

o Plant the same or another regulated corn material and follow the requirements for that regulated corn material.

o In Hawaii and Puerto Rico, continuous cropping of corn may occur, but must include at least a 30-day irrigated fallow period after each harvest, during which time the plots will be monitored for germ inating corn plants. In Puerto Rico, rainfall may substitu te for irrigation.

Volunteer Monitoring

 If the EUP trial is destroye d prior to flowering, no volunt eer monitoring is required.

 EUP plots that are allowed to flower will be monitored for volunteer plants to prevent persistence of EUP test plants in the e nvironment. Any volunt eer plants will be destroyed prior to flowering using appr oved Final Disposition methods (see “Nonharvested plots (including bor der) and volunteer monitoring”).

## Monsanto Company CR240-13E3 Page 166 of 166 Termination of Experimental Use Program In the event that the EUP test plants receive EPA registration prior to the expiration date of the EUP, trials shall be managed as outlined below:

 All terms and conditions of this EUP program shall be discontinued for trials that do not contain any unregistered PIPs, and registered PIPs shall be managed in accordance with the applicable registration.

 Trials that contain unregistered PIPs shall be managed in accordance with the terms and conditions of the Experimental Use Permit.