Exhibit 31.1

CERTIFICATION

I, Michael L. Krall, certify that:

1.    
          I have reviewed this annual report on Form 10-KSB of PURE Bioscience.

2.    
          Based on my knowledge, this annual report does not contain any untrue statement
          of a material fact or omit to state a material fact necessary to make the
          statements made, in light of the circumstances under which such statements were
          made, not misleading with respect to the period covered by this report;

3.    
          Based on my knowledge, the financial statements, and other financial information
          included in this annual report, fairly present in all material respects the
          financial condition, results of operations and cash flows of the small business
          issuer as of, and for, the periods presented in this report;

4.    
          The small business issuers other certifying officer(s) and I are
          responsible for establishing and maintaining disclosure controls and procedures
          (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e) for the small business
          issuer and have:

|a) | Designed such disclosure controls and procedures, or caused such disclosure
                    controls and procedures to be designed under our supervision, to ensure that
                    material information relating to the small business issuer, including its
                    consolidated subsidiaries, is made known to us by others within those entities,
                    particularly during the period in which this report is being prepared;
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|b) | Designed such internal control over financial reporting, or caused such
                    internal control over financial reporting to be designed under our supervision,
                    to provide reasonable assurance regarding the reliability of financial reporting
                    and the preparation of financial statements for external purposes in accordance
                    with generally accepted accounting principles;
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|c) | Evaluated the effectiveness of the small business issuers disclosure
                    controls and procedures; and presented in this report our conclusions about the
                    effectiveness of the disclosure controls and procedures as of the end of the
                    period covered by this report based on such evaluation; and
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|d) | Disclosed in this report any change in the small business issuers
                    internal control over financial reporting that occurred during the small
                    business issuers most recent fiscal quarter (the small business
                    issuers fourth fiscal quarter in the case of an annual report) that has
                    materially affected or is reasonably likely to materially affect, the small
                    business issuers internal control over financial reporting; and
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5.    
          The small business issuers other certifying officer(s) and I have
          disclosed, based on our most recent evaluation of internal control over
          financial reporting, to the small business issuers auditors and the audit
          committee of small business issuers board of directors (or persons
          performing the equivalent functions):

|a) | All significant deficiencies and material weaknesses in the design or operation
                    of internal control over financial reporting which are reasonably likely to
                    adversely affect the small business issuers ability to record, process,
                    summarize and report financial information; and
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|b) | Any fraud, whether or not material, that involves management or other employees
                    who have a significant role in the small business issuers internal control
                    over financial reporting.
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Date: October 26, 2006

/s/ Michael L. KrallMichael L. Krall President and Chief
Executive Officer