EX-4.1





 Exhibit 4.1 
  





 
 C0000000230 | M 
Governed by the Business
Corporations Act (Québec) Régie par la Loi sur les sociétés par actions (Québec) 
Number Numéro 
00000000 
Shares Actions 
* * * * 0 * * * * * * * * * 
* * * * * 0 * * * * * * * * 
* * * * * * 0 * * * * * * * 
* * * * * * * 0 * * * * * * 
* * * * * * * * 0 * * * * * 
THIS CERTIFIES THAT
**SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN7602731
0200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare* LES PRÉSENTES ATTESTENT QUE
Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.
zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN7 6027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc SPECIMEN
..zero****SPECIMEN76027310200000000R epare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutic
s*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPE

CIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN760273102000
00000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Therapeutics*Inc.zero****SPECIMEN76027310200000000Repare*Thera 
IS THE REGISTERED HOLDER OF
**076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Ther
apeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****0760273102 EST LE PORTEUR INSCRIT DE
00000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc
..zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repa re*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc * * * 0 *
..zero****076027310200000000Repare*Therapeutics*Inc * * .zero****076 027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeut
ics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000
000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero
****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Th
erapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****076027310200000000Repare*Therapeutics*Inc.zero****07602731 
FULLY PAID AND NON-ASSESSABLE COMMON SHARES WITHOUT PAR ACTIONS ORDINAIRES SANS VALEUR NOMINALE ENTIÈREMENT VALUE IN THE CAPITAL OF LIBÉRÉES DU CAPITAL-ACTIONS DE 
Repare Therapeutics Inc. Thérapeutiques Repare Inc. 
transferable on the books of the
Corporation only upon surrender of this certificate properly transférables dans les registres de la Société seulement sur remise de ce certificat endossé en endorsed. bonne et due forme. 
This certificate is not valid unless countersigned by the Transfer Agent and Registrar of the Ce certificat n’est valide que s’il a été contresigné
par l’agent de transfert et agent comptable des Corporation. registres de la Société. 
IN WITNESS WHEREOF the Corporation has caused this
certificate to be signed on its behalf by EN FOI DE QUOI la Société a fait signer le présent certificat en son nom au moyen des fac-the facsimile signatures of its duly authorized officers. similés de signature de ses
dirigeants dûment autorisés. 
COUNTERSIGNED AND REGISTERED CONTRESIGNÉ ET IMMATRICULÉ 
COMPUTERSHARE TRUST COMPANY, N.A. 
(CANTON, MA, JERSEY CITY, NJ AND LOUISVILLE, KY) TRANSFER
AGENT AND REGISTRAR 
AGENT DE TRANSFERT ET AGENT COMPTABLE DES REGISTRES

Dated: Jun 12, 2020 Le : 12 juin 2020 
COUNTERSIGNED AND REGISTERED
CONTRESIGNÉ ET IMMATRICULÉ 
COMPUTERSHARE INVESTOR SERVICES INC.

OR 
SERVICES AUX INVESTISSEURS COMPUTERSHARE INC. (MONTREAL) (TORONTO)
TRANSFER AGENT AND REGISTRAR 
AGENT DE TRANSFERT ET AGENT COMPTABLE DES REGISTRES 
Chief Executive Officer Chef de la direction 
Chief Financial Officer Chef des finances

By / Par ______________________________ 
Authorized
Officer—Représentant Autorisé 
By / Par ______________________________ 
Authorized Officer—Représentant Autorisé 
The shares represented by this
certificate are transferable at the offices of Computer share Investor Services Inc. in Montreal, QC and Toronto, ON or at the offices of Computershare Trust Company, N.A. in Canton, MA, Jersey City, NJ and Louisville, KY. 
Les actions représentées par ce certificat peuvent être transférées aux bureaux de Services aux Investisseurs Computershare inc .à
Montréal, QC et Toronto, ON ou aux bureaux de Computershare Trust Company, N.A. à Canton, MA, Jersey City, NJ et à Louisville, KY.

CSAE_WIP_RPKQ_C01.mtl.pulls/000001/000001/i 
CUSIP 760273102 
ISIN US7602731025 












 



 
 The shares represented by this certificate have rights and restrictions attached thereto and the Corporation will, on request, provide
the text of those rights and restrictions to a shareholder without charge. 
Les actions représentées par ce certificat sont assorties de droits et
restrictions et la Société fournira sans frais à un actionnaire le texte de ces droits et restrictions sur demande. 
The fallowing
abbreviations shall be construed as though the words set forth bclm•1 opposite each abbreviation ¥•Jere 
11.~itten out in full ~ohe1e such
abbreviation appears: 
TEN COM - as tcnanls in common 
TEN ENT - as tenants by
the entireties 
JT TEN - as joint tenants ._·.tth rights of survivorship and not as tenants in common 
(Name) CUST (Name) UMIF - (Mame) as Custodian fo1 (Mame) under the 
GIFT MIN ACT (State)
(Slate) Uniform Gifts to Minors Act 
Additional abbreviations may also be used though not in lhc above list. 
For value received the undersigned hereby sells, assigns and transfers unto 
Les abrCviations
suivantcs doivcnt Ctrc intcrprCtCcs commc si lcs expressions carrcspondanlcs Ctaicnt Ccritcs en 
toutes Iett1es : 
TEN COM - 3 titre de propriCtaircs en commun 
TEN ENT - 3 titre de tenants unaaircs 
JTTEN - ati1re de cop1op1ietai1es avec gain de su1vie et non atitre de p1op1ietai1es 
en commun

(Nom) CUST (Norn) UNIF - (Norn) atitre dc.dcpositairc pour (Norn) envertu de la UnWorm Gifts to 
GIFT MIN ACT (Bat) Mino1s Act de (Etat) 
Des abrCviations aulrcs quc ccllcs qui sont donnCcs
ci-dcssus pcuvcnt aussi ctrc utilisCcs. 
Pour valeur rei;;ue, le soussigne vend, cede et transfere par les presentes a 
lnse1t name and add1ess of transferee 
lnse1e1 le nom et l’ad1esse du cessionnaire

shares represented by this certificate and does hereby irrevocably constitute and appoint 
actions representees par le present certificat et nom me irrevocablement 
the attorney of the
undersigned to transfer the said shares on the books of the Corporation with full power of substitution in the premises. 
le fonde de pouvoir du soussigne charge
d’inscrire le transfer! desdites actions aux registres de la Societe avec plei n pouvoir de substitution a eel egard. 
LE: 
DATE: 
Signature of Shareholder I Signature de l’actionnaire 
Signature of Guarantor I Signature du garant 
Signature Guarantee: The signature on this
assignment must correspond with the name as written upon the face of the certificate(s). in every particular. >.•.qthout alreration or enlarge1rent, or any change whatsoever and must be guaranteed by a major Canadian Schedule I chartered
bank or a member of an a:x:eptable Medallion Signature Guarantee Program (STAMP. SEMP. MSP} The Guarantor must affix a stamp bearing the actual words “Signa1ure Guaran1eed”. 
In the USA, signature guarantees must be done by members of a ‘fo,Jledallion Signa1ure Guaran1ee Program” only. 
Signature guarantees are not accepted from Treasury Branches, Credit Unions or Caisses populaires unless they are members of the Stamp Medallion Program. 
SECURITY INSTRUCTIONS - INSTRUCTIONS DE SECURITE 
11 llS IS WA1 CRMAl1KCD PAP LA, DO N01 ACCCPl
wm IOUT NOTINO 
WA I CRMARK HOl 1’.> TO l lGHT TO VERIFY Wf\TFRM/IRK.

PAPILH r tl IGHAN I~ . NE PllS ACCFPTFn SANS VFRIFIF.A I A PRFSFNCE 
DU
FILIGRANE. POU i~ CE FAIRE. PLACER A LA LUMIERE. 
Garantie de signature : La signature apposee aux fins de cette cession cbit correspondre ex~tement au nom qui est
inscrit au recto du certificat. sans aucun changement. et doit etre garantie par une banque a charte canadienne de l’Annexe 1 ou un membre d’un programme de garantie de signature Medallion ~ceptable (STAMP, SEMP, MSP} Le garant doit
app::iser un timbre portant la mention • Signature garantie > ou « Signature Guaranteed >. 
Aux Etals-Unis, seuls les membres d’un «
fo,Jledallion Signature Guarantee Program > peuvent garantir une signature. 
Les garanties de signature ne peuvent pas etre faires par des caisses d’epargne
(«Treasury Branches•), des caisses de credit (« Credit Unions >) ou des Caisses populaires, a moins qu’elles ne soient membres du programme de garantie de signature Medallion STAMP.