U.S. SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                  FORM 10-QSB

                AMENDED QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF
                      THE SECURITIES EXCHANGE ACT OF 1934


               FOR THE QUARTERLY PERIOD ENDED September 30, 2005

                         COMMISSION FILE NO. 0-28413


                                HUMAN BIOSYSTEMS
       (Exact name of small business issuer as specified in its charter)


            CALIFORNIA                                   77-0481056
(State or other jurisdiction of            (I.R.S. Employer Identification No.)
 incorporation or organization)


                               1127 HARKER AVENUE
                          PALO ALTO, CALIFORNIA 94301
                    (Address of principal executive offices)

                                  650-323-0943
                          (Issuer's telephone number)

Check whether the issuer (1) filed all reports required to be filed by Section
13 or 15(d) of the Exchange Act during the past 12 months (or for such shorter
period that the registrant was required to file such reports), and (2) has been
subject to such filing requirements for the past 90 days. Yes [X]   No [ ]

Indicate by check mark whether the registrant is a shell company (as defined
in Rule 12b-2 of the Exchange Act)   Yes [ ]   No  [X]

At September 30, 2005, the registrant had outstanding 64,196,000 shares of
common stock, no par value

Transitional Small Business disclosure format:  Yes [ ]   No  [X]

==============================================================================



                                HUMAN BIOSYSTEMS
                               TABLE OF CONTENTS
                                                                           Page
PART I - FINANCIAL INFORMATION

ITEM 1.  FINANCIAL STATEMENTS

CONDENSED BALANCE SHEET (UNAUDITED) -- as of September 30, 2005              F-2

CONDENSED STATEMENTS OF OPERATIONS (UNAUDITED)
For the Three and Nine Month Periods Ended September 30, 2005 and 2004
and the Period from February 26, 1998 (Inception) through September 30, 2005 F-3

CONDENSED STATEMENT OF STOCKHOLDERS' DEFICIT (UNAUDITED)
For the Nine Months Ended September 30, 2005       	                     F-4

CONDENSED STATEMENTS OF CASH FLOWS (UNAUDITED)
For the Nine Months Ended September 30, 2005 and 2004,
and the Period from February 26, 1998 (Inception) through September 30, 2005 F-5

NOTES TO CONDENSED FINANCIAL STATEMENTS (UNAUDITED)                          F-6

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OR PLAN OF OPERATION           2

ITEM 3.  CONTROLS AND PROCEDURES                                             21

PART II - OTHER INFORMATION                          	                     21

ITEM 1.  LEGAL PROCEEDINGS                                                   21

ITEM 2.  UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS         21

ITEM 3.  DEFAULTS UPON SENIOR SECURITIES         			     22

ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS                 22

ITEM 5.  OTHER INFORMATION                                                   22

ITEM 6.  EXHIBITS                                                            22

SIGNATURES                                                                   22

===============================================================================

                        PART I - FINANCIAL INFORMATION

ITEM 1.  FINANCIAL STATEMENTS

                                       HUMAN BIOSYSTEMS
                                (A DEVELOPMENT STAGE COMPANY)
                                   CONDENSED BALANCE SHEET
                                      SEPTEMBER 30, 2005
                                         (UNAUDITED)

                                            ASSETS

<TABLE>
<CAPTION>
<S>                                                                       <C>

Current assets
        Cash                                                            $   60,100
        Prepaid expenses                                                     6,200
        Investment in marketable securities                                 67,800
                                                                        ----------
                Total current assets                                       134,100

Fixed assets, net                                                           10,000
                                                                        ----------

Total assets                                                            $  144,100
                                                                        ==========
LIABILITIES AND STOCKHOLDERS' DEFICIT

Current liabilities
        Accounts payable                                                $  142,700
        Accrued liabilities                                                 62,300
        Other liabilities                                                  175,000
        Public relations payable                                           442,300
        Due to stockholders                                                155,900
                                                                        ----------
                Total current liabilities                                  978,200
                                                                        ----------
Total liabilities                                                          978,200

Commitments and contingencies                                                   --

Stockholders' equity
    Preferred stock; no par or stated value; 5,000,000 shares
          authorized, no shares issued or outstanding                           --
    Common stock; no par or stated value; 145,000,000 shares
           authorized, 64,885,300 shares issued
           and 64,196,000 shares outstanding                            18,431,000
    Investment in marketable securities held in escrow                     (67,800)
    Accumulated other comprehensive loss                                   (11,800)
    Accumulated deficit during development stage                       (19,185,500)
                                                                       ------------
                Total stockholders' deficit                               (834,100)
                                                                       ------------

Total liabilities and stockholders' deficit                             $  144,100
                                                                       ============

                 See Accompanying Notes To Financial Statements

</TABLE>
<page>F-2

                                       HUMAN BIOSYSTEMS
                                (A DEVELOPMENT STAGE COMPANY)
                              CONDENSED STATEMENTS OF OPERATIONS
                                         (UNAUDITED)
<TABLE>
<CAPTION>                                                         <C>                       <C>                        <C>
<S>                                                        Three Months Ended          Nine Months Ended       February 26, 1998
                                                             September 30,                September 30,      (Inception) Through
                                                         2005            2004           2005         2004     September 30, 2005
                                                     --------------  -----------       -------      -------    -----------------

Revenue                                          $         --     $      --        $      --     $      --      $        --

Operating expenses
    General and administrative
       Stock based compensation                        167,900        54,500         450,300       329,700         4,124,100
       Public relations                              2,084,300            --       3,202,600            --         3,202,600
       Other general and administrative expenses       290,100       202,400         788,800       467,900         6,358,400
                                                     -----------   -----------     ----------     ---------       -----------
    Total general and administrative                 2,542,300       256,900       4,441,700       797,600        13,685,100
    Research and development                            42,300        42,300         138,300       154,600         2,067,100
    Sales and marketing                                     --        35,500          25,400        93,900           820,800
                                                     -----------   -----------    -----------    ----------       -----------
            Total operating expenses                 2,584,600       334,700       4,605,400     1,046,100        16,573,000
                                                     -----------   -----------    -----------    ----------       -----------
Loss from operations                                (2,584,600)     (334,700)     (4,605,400)   (1,046,100)      (16,573,000)

Other income (expense)
    Loan fees                                               --            --              --            --          (750,000)
    Bad debt related to other receivable                    --            --              --            --          (502,300)
    Loss on investment in marketable securities             --            --              --            --          (762,600)
    Forgiveness of debt                                 80,100            --          80,100            --            80,100
    Interest income                                         --            --              --            --             2,700
    Interest expense                                        --          (100)             --      (366,200)         (673,200)
                                                     -----------   -----------    -----------   -----------      ------------
Loss before provision for income taxes               (2,504,500)    (334,800)     (4,525,300)   (1,412,300)      (19,178,300)

Provision for income taxes                                  --             --          1,600            --             7,200
                                                     -----------   -----------    -----------   -----------      ------------

Net loss                                             (2,504,500)     (334,800)    (4,526,900)   (1,412,300)      (19,185,500)
                                                    ------------   -----------    -----------   -----------      ------------

Other comprehensive income(loss), net tax
   Unrealized gain(loss) on investment in
    marketable securities                               25,200             --         (2,000)           --           (11,800)
                                                    -----------   ------------   ------------  ------------     -------------

Total comprehensive loss                           $(2,479,300)   $  (334,800)   $(4,528,900)  $(1,412,300)     $(19,197,300)
                                                    ===========   ============   ============= ============     ==============

Basic and diluted loss per common share            $     (0.04)   $     (0.01)   $     (0.08)  $     (0.04)     $      (1.01)
                                                    ===========   ============   ============= ============     ==============
Basic and diluted weighted average
  common shares outstanding                         60,871,400    38,412,316       56,261,437    35,614,160        18,926,650
                                                    ===========   ============   =============  ============    ==============

        See Accompanying Notes To Financial Statements

</table>
<page>F-3
                                       HUMAN BIOSYSTEMS
                                (A DEVELOPMENT STAGE COMPANY)
                         CONDENSED STATEMENT OF STOCKHOLDERS' DEFICIT
                                         (UNAUDITED)

<table>
<caption>

                                                    <c>             <c>              <c>                <c>

                                                                       Investment
                                                                           in          Accumulated     Accumulated
                                                    Common              Marketable        Other       Deficit During    Total
                                            ----------------------      Securities     Comprehensive    Development  Stockholders'
                                              Shares      Amount     Investments PLC      Loss            Stage         Deficit
                                           ----------  ----------   ---------------  --------------  ------------- -------------
Balance December 31, 2004                  51,447,000  $14,423,600   $    (68,800)    $    (9,800)   $(14,658,600)  $  (313,600)


Issuance of common stock for cash (net of
   offering costs of $1,539,900),weighted
   average price of $0.09                   5,697,100      486,300             --              --              --       486,300

Issuance of common stock for cash related
  to Investment Agreement, weighted
  average price of $0.71                      315,600      225,600             --              --              --       225,600

Issuance of common stock for services,
  weighted average price of $0.57             762,200      431,200             --              --              --       431,200

Issuance of common stock for public
  relations, $0.33                            750,000      247,500             --              --              --       247,500

Issuance of common stock for bonus shares
  related to public relations agreement,
  weight average price $0.59                4,239,900    2,512,800             --              --              --     2,512,800

Issuance of common stock in satisfaction
  of account payable, $0.32                     5,300        1,700             --              --              --         1,700

Stock based compensation related to
  granting of options                              --       19,100             --              --              --        19,100

Stock options and warrants exercised,
  weighted average price of $0.09             908,400       83,200             --              --              --        83,200

Cashless exercise of stock options by
  consultant                                   70,500           --             --              --              --            --

Comprehensive loss, net of tax
  Net loss                                         --           --             --              --       (4,526,900)   (4,526,900)
  Unrealized loss on investment in
   marketable securities                           --           --          1,000          (2,000)              --        (1,000)
                                                                                                                     ------------
Total comprehensive loss                           --           --             --              --               --    (4,527,900)
                                           ----------   ----------   -------------      ------------  -------------  ------------
Balance September 30, 2005(Unaudited)      64,196,000 $ 18,431,000   $    (67,800)    $   (11,800)    $(19,185,500) $   (834,100)
                                           ==========  ===========   =============      ============  =============  ============

                     See Accompanying Notes To Financial Statements

</table>
<page>F-4


                                   HUMAN BIOSYSTEMS
                                (A DEVELOPMENT STAGE COMPANY)
                             CONDENSED STATEMENTS OF CASH FLOWS
                                         (UNAUDITED)

<table>
<caption>

                                                       <c>            <c>                     <c>

                                                         Nine months    Nine months   February 26, 1998
                                                             ended         ended          (Inception)
                                                         September 30,  September 30,      Through
                                                             2005          2004       September 30, 2005
                                                           -------        -------     ------------------
Cash flows from operating activities:
 Net loss                                                $(4,526,900)  $(1,412,300)   $  (19,185,500)
 Adjustments to reconcile net loss to net
 cash used by operating activities:
   Stock based compensation                                  450,300       329,700         4,124,100
   Public relations-paid or to be paid in common stock     3,202,600	        --         3,202,600
   Depreciation                                                1,200         1,100            10,800
   Forgiveness of debt                                        80,100	        --            80,100
   Deemed interest expense                                        --            --            92,800
   Interest expense paid in common stock                          --       365,300           487,800
   Amortization of discount and loan fees on notes payable        --            --           774,800
   Loss on investment in markertable securities                   --            --           762,600
   Bad debt related to other receivables                          --            --           502,300
 Changes in operating assets and liabilities:
   Change in prepaid expenses                                 (6,200)       14,100            (6,200)
   Change in accounts payable                               (160,300)       90,600           148,700
   Change in accrued liabilities                                 600            --           171,700
   Changes in other liabilities                              175,000	    40,200           175,000
                                                            ---------     ----------      -----------
          Net cash used by operating activities             (783,600)     (571,300)       (8,658,400)

Cash flows from investing activities:

  Purchase of fixed assets                                   (11,000)           --           (20,800)
                                                            ---------     ---------       -----------
    Net cash used by investing activities                    (11,000)           --           (20,800)

 Cash flows from financing activities:
   Change in due to stockholders                            (219,100)      312,100         1,017,800
   Proceeds from issuance of common stock                    795,100       252,100         7,587,300
   Proceeds from borrowing on notes payable                       --            --           323,100
   Principal payments on notes payable                            --            --           (97,400)
   Principal payments on stock subject to rescission              --            --           (41,500)
   Change in other receivables                                    --            --           (50,000)
                                                            ---------    ----------       -----------
     Net cash provided by financing activities               576,000       564,200         8,739,300
                                                            ---------    ----------       -----------
  Net increase (decrease) in cash                           (218,600)       (7,100)           60,100

  Cash, beginning of period                                  278,700         7,400               --
                                                            ---------    ----------       -----------
  Cash, end of period                                      $  60,100     $     300          $ 60,100
                                                            =========    ==========       ===========
  Supplemental disclosure of cash flow information:
  Cash paid for income taxes                               $   1,600     $      --          $  6,400
                                                           =========     ==========       ===========
  Cash paid for interest                                   $      --     $      --          $ 12,900
                                                           =========     ==========       ===========
Schedule of non-cash financing activities:
  Issuance of common stock in satisfaction of
   accounts payable (excluding interest of $26,600)        $      --     $  48,600          $ 48,600
                                                           ==========    ==========       ===========
  Issuance of common stock in satisfaction of
   accrued liabilities (excluding interest of $20,000)     $      --     $  36,700          $ 36,700
                                                           ==========    ==========       ===========
  Issurance of common stock to employees of Russian
   Branch for accrued liabilities (excluding services of
     ($28,500)                                             $      --     $  30,400          $ 30,400
                                                           ==========    ==========       ===========
  Issuance of common stock in satisfaction of due to
   stockholders (excluding interest of $318,700)           $      --     $ 594,400          $594,400
                                                           ==========    ==========       ===========
  Issuance of common stock in satisfaction of accounts
   payable                                                 $   1,700	 $      --          $  1,700
                                                           ==========	 ==========       ===========
      See Accompanying Notes To Financial Statements


</table>
<page>F-5
                                HUMAN BIOSYSTEMS
                         (A DEVELOPMENT STAGE COMPANY)
                      NOTES TO CONDENSED FINANCIAL STATEMENTS
                                  (UNAUDITED)

Human BioSystems (hereinafter referred to as the "Company") is a development
stage company incorporated on February 26, 1998 under the laws of the state of
California.  The business purpose of the Company is to develop the technology
for preservation of certain biologic material, including platelets (a blood
component), red blood cells, heart valves, tissue and organs.  The Company is in
the seventh year of its research and development activities.  The Company's goal
is to develop the technology to extend and maintain functionality of these
materials for much longer periods of time than is currently possible.

The accompanying unaudited condensed financial statements have been prepared in
accordance with Securities and Exchange Commission requirements for interim
financial statements.  Therefore, they do not include all of the information and
footnotes required by accounting principles generally accepted in the United
States for complete financial statements.  The financial statements should be
read in conjunction with the Form 10-KSB for the year ended December 31, 2004 of
Human BioSystems (the "Company").

The interim financial statements present the condensed balance sheet, statements
of operations, stockholders' deficit and cash flows of Human BioSystems.  The
financial statements have been prepared in accordance with accounting principles
generally accepted in the United States.

The interim financial information is unaudited.  In the opinion of management,
all adjustments necessary to present fairly the financial position of the
Company as of September 30, 2005 and the results of operations and cash flows
presented herein have been included in the financial statements.  Interim
results are not necessarily indicative of results of operations for the full
year.

The preparation of financial statements in conformity with accounting principles
generally accepted in the United States requires management to make estimates
and assumptions that affect the reported amounts of assets and liabilities and
disclosure of contingent assets and liabilities at the date of the financial
statements and the reported amounts of revenues and expenses during the
reporting period. Actual results could differ from those estimates.

<page>F-6

2.	STOCK-BASED EMPLOYEE COMPENSATION

The Company applies Accounting Principles Board ("APB") Opinion No. 25,
Accounting for Stock Issued to Employees, and Related Interpretations, in
accounting for stock options issued to employees. Under APB No. 25, employee
compensation cost is recognized when the estimated fair value of the underlying
stock on date of the grant exceeds the exercise price of the stock option. For
stock options and warrants issued to non-employees, the Company applies SFAS No.
123, Accounting for Stock-Based Compensation, which requires the recognition of
compensation cost based upon the fair value of stock options at the grant date
using the Black-Scholes option pricing model.

The following table represents the effect on net loss and loss per share if the
Company had applied the fair value based method and recognition provisions of
Statement of Financial Accounting Standards (SFAS) No. 123, "Accounting for
Stock-Based Compensation", to stock-based employee compensation:

		                               Nine months ended Sept 30,
		                                  2005		2004
                                            -------------   ---------------
Net loss, as reported	                    $(4,526,900)     $(1,412,300)
Add: Stock-based employee compensation
 expense included in reported loss,
 net of related tax effects		            --		  20,000
Deduct: Total stock-based employee
 compensation expense determined under
 fair value based methods for all awards,
 net of related tax effects		       (21,900)		 (84,700)
                                           --------------    ------------
Pro forma net loss	                   $(4,548,800)      $(1,477,000)
                                           ==============    ============
Net loss per common share
 Basic and diluted loss, as reported	   $	 (0.08)	     $	   (0.04)
                                           ==============    ============
 Basic and diluted loss, pro forma	   $     (0.08)      $     (0.04)
                                           =============     ============

<page>F-7

3.	OTHER LIABILITIES

Other liabilities consist of deposits from investors for which the Company owes
500,000 shares of common stock totaling $175,000 as of September 30, 2005.

4.	RELATED PARTY TRANSACTIONS

Due to stockholders consist of the following as of September 30, 2005:

Wages payable to stockholder employees		$ 142,000

Accrued vacation for stockholder employees	   13,900
                                               -----------
				               $  155,900
                                               ===========
5.	COMMON STOCK

During the first quarter 2005, the Company issued 1,746,100 shares of common
stock for cash totaling $262,200 (including offering costs of $609,900).

During the first quarter 2005, the Company issued 282,200 shares of common stock
for services totaling $31,600.

During the first quarter 2005, the Company issued 111,100 shares of common stock
in relation to the exercise of warrants for cash totaling $1,100.

During the second quarter 2005, the Company issued 3,951,000 shares of common
stock for cash totaling $229,800 (including offering costs of $924,300).

During the second quarter 2005, the Company issued 300,000 shares of common
stock pursuant to a termination agreement with a consultant totaling $249,000.

During the second quarter 2005, the Company issued 487,300 shares of common
stock in relation to the exercise of options and warrants for cash totaling
$42,800.

During the third quarter 2005, the Company issued 310,000 shares of common stock
in relation to the exercise of options and warrants for cash totaling $39,300.

During the third quarter 2005, the Company issued 70,500 shares of common stock
in relation to a cashless exercise of options.  In order to initiate the
exercise, the holder gave up options to purchase 29,500 shares of the Company's
common stock as consideration for the exercise in place of cash. The 29,500
shares was the equivalent of the cash the Company would have received under the
terms of the option agreement.

<page>F-8

During the third quarter 2005, the Company recognized offering costs totaling
$5,700 due to a foreign currency translation loss recognized in relation to cash
received during the second quarter for the sale of common stock.

During the third quarter 2005, the Company issued 5,300 shares of common stock
in satisfaction of accounts payable totaling $1,700.

During the third quarter 2005, the Company issued 180,000 shares of common stock
for services totaling $150,600.

Loan Agreement - During October 2004, the Company entered into a Loan Agreement
(the "Loan Agreement") with an unaffiliated individual (the "Lender").  The Loan
Agreement called for the Lender to loan an aggregate of Euros 2,300,000 to the
Company (the "Loan") with interest at the rate of three percent per annum,
payments of interest due monthly and all principal plus accrued but unpaid
interest due and payable on November 1, 2007.  Repayment of the Loan was to be
secured by 23,000,000 shares of the Company's common stock issuable under
Regulation S under the Securities Act of 1933, as amended (the "Shares").
Pursuant to the Loan Agreement and an Escrow Agreement between the Lender and
the Company, the 23,000,000 Shares were issued during October 2004 and were
delivered to the Lender to hold until funds for repayment of the Loan have been
delivered to the escrow agent.  The Loan Agreement was declared in default, with
the Shares to be immediately returned to the Company, as the Loan funds were not
delivered by the 15th calendar day following the date of the Loan Agreement
(November 13, 2004).  The shares were cancelled during February and March 2005.
Accordingly, the Company did not record the shares as outstanding prior to the
cancellation.

Public Relations Agreement - During March 2005, and subsequently amended during
April 2005, the Company entered into an agreement with a public relations and
promotions services company for consulting services.  The public relations and
promotions services company will promote the Company to the investment community
and the general public through press releases and other communications, all of
which must be approved in advance by the Company. The term of the agreement is 6
months, subject to prior termination. In consideration of the services being
performed, the Company will issue compensation shares equal to 30% of the
increase in buy volume of the Company's common stock directly attributable to
the public relations and promotions services company, as defined in the
agreement. The Company will also issue bonus shares of 10% of the increase in
buy volume of the Company's common stock in the event the sales price of the
Company's common stock equals or exceeds $0.25 per share. Additionally, the
Company has agreed to issue 6.0 million shares of common stock to be held by an
escrow agent.  Through September 30, 2005 the Company released 4,239,900 shares
of common stock totaling $2,512,800 in consideration of this agreement.
Additionally, the Company recorded public relations payable for approximately
899,500 additional shares to be released at a future date valued at $442,300.

<page>F-9

During June 2005, the Company entered into a second agreement with the public
relations and promotions services company for additional consulting services in
exchange for 750,000 shares of the Company's common stock valued at $247,500.
The Company issued the shares in June 2005.

Investment Agreement - During June 2004, the Company entered into an Investment
Agreement (the "Investment Agreement") with Dutchess Private Equities Fund II,
LP ("Dutchess") effective June 28, 2004.  Pursuant to the terms of the
Investment Agreement, the Company may offer, through a series of puts, and
Dutchess must purchase up to 38,000,000 shares of the Company's common stock
with an aggregate purchase price up to $5,000,000. Pursuant to the Investment
Agreement, Dutchess acquired 30,000 shares of the Company's common stock in
exchange for approximately $16,800 during April 2005, 229,600 shares for
approximately $158,900 during August 2005 and  56,000 shares for approximately
$49,900 during September 2005.

Shares held in escrow - As of September 30, 2005, approximately 690,000 shares
of the Company's common stock are issued and held in trust accounts.  The trust
accounts were set up to receive and hold cash from investors in exchange for
shares of common stock.  These shares will be recognized as outstanding upon
receipt of cash or other consideration.

6.	OTHER ITEMS

Executive Consulting Agreement - During August 2005, the Company entered into an
Executive Consulting Agreement with Dr. David Winter.  Pursuant to the
agreement, Dr. Winter will serve as President of the Company.  In that capacity,
he will oversee the Company's platelet and organ development programs and
supervise negotiations with the Company's alliance partners.  Dr. Winter
succeeds Harry Masuda who will continue as the Company's Chief Executive
Officer.

In consideration for these services, Dr. Winter will receive a monthly retainer
of $3,000.  The Company also granted options to purchase 96,000 shares of the
Company's common stock, at an exercise price of $0.73 per share.  The options
vest monthly for twelve months beginning with the date of grant, and expire in
five years.  The shares are valued at $44,600 using the Black Scholes model and
will be expensed through the vesting period.

<page>F-10

Board appointment - During September 2005, the Company appointed Dr. Larry
McCleary to fill a vacancy created by Dr. George Tsukuda's resignation in
September 2005.  The Company granted Dr. McCleary options to purchase 50,000
shares of the Company's common stock, at an exercise price of $0.73 per share.
The options vest annually for three years at 30%, 30% and 40% beginning with the
date of grant, and expire in five years.  The shares are valued at $30,100 using
the Black Scholes model and will be expensed through the vesting period.

Forgiveness of debt - During the third quarter 2005 the Company recorded
forgiveness of debt from a vendor totaling $80,100.  The vendor had previously
received shares of the Company's common stock in satisfaction of certain
invoices.  However, due to additional realization by that vendor upon the sale
of the common stock, the vendor forgave additional invoices totaling $80,100.

7.	GOING CONCERN

The accompanying financial statements have been prepared on a going concern
basis, which contemplates the realization of assets and the satisfaction of
liabilities in the normal course of business.  The Company is in the development
stage, has no operating revenue and incurred a net loss of $4,526,900 for the
nine months ended September 30, 2005.  The Company is in the eighth year of
research and development, with an accumulated loss during the development stage
of $19,185,500.  As of September 30, 2005, management is uncertain as to the
completion date or if any of the Company's products will be completed at all.

Management's plan, in this regard, is to raise financing of approximately
$2,500,000 through a combination of equity and debt financing.  Management
believes this amount will be sufficient to finance the continuing research for
the next twelve months.  However, there is no assurance that the Company will be
successful in raising such financing.

These conditions give rise to substantial doubt about the Company's ability to
continue as a going concern.  These financial statements do not include
adjustments relating to the recoverability and classification of reported asset
amounts or the amount and classification of liabilities that might be necessary
should the Company be unable to continue as a going concern.  The Company's
continuation as a going concern is dependent upon its ability to obtain
additional financing or sale of its common stock as may be required and
ultimately to attain profitability.

On July 19, 2005, Human BioSystems ("HBS") issued an Exchange Offer to its Reg S
stockholders in Germany to exchange one share of HBS common stock for each of
the shares of Reg S Stock outstanding before or upon the de-listing date when
the Reg S Stock is no longer tradable.  This Exchange Offer is only applicable
to HBS Reg S stockholders in Germany and expires in December 2005.

7.	SUBSEQUENT EVENTS

During October, 2005, the Company issued a put notice to Dutchess Private
Equities Fund, II, LP and received the amount of $65,000 for which the Company
issued 108,605 shares of unrestricted common shares pursuant to the agreement
signed between the Company and Dutchess during June, 2004.

In October, 2005, the Company increased the number of shares allocated under the
public relations agreement signed between the Company and a public relations
firm in March, 2005 to 7 million shares. The agreement was also extended an
additional six months from September 2005 to March, 2006.

In October, 2005, the Company initiated the transfer of 1 million shares of
Company common shares to the Company's escrow account for the purpose of
satisfying any stock payments due under the terms of the agreement signed
between the Company and the public relations firm. The transfer is pending as of
November 8, 2005.

During October, 2005, the Company entered into a non-exclusive consulting and
capital raising agreement with an investment banking firm to assist the Company
raise capital on a success fee basis. The agreement calls for a cash fee and
warrants based on the capital raised. The term of the agreement is 6 months.

<page>F-11

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OR PLAN OF OPERATION.

THIS QUARTERLY REPORT CONTAINS FORWARD-LOOKING STATEMENTS WITHIN THE MEANING OF
SECTION 21E OF THE SECURITIES EXCHANGE ACT OF 1934, INCLUDING, WITHOUT
LIMITATION, STATEMENTS REGARDING OUR EXPECTATIONS, BELIEFS, INTENTIONS OR FUTURE
STRATEGIES THAT ARE SIGNIFIED BY THE WORDS "EXPECTS", "ANTICIPATES", "INTENDS",
"BELIEVES", OR SIMILAR LANGUAGE.  THESE FORWARD-LOOKING STATEMENTS INVOLVE
RISKS, UNCERTAINTIES AND OTHER FACTORS.  ALL FORWARD-LOOKING STATEMENTS INCLUDED
IN THIS DOCUMENT ARE BASED ON INFORMATION AVAILABLE TO US ON THE DATE HEREOF AND
SPEAK ONLY AS OF THE DATE HEREOF.  THE FACTORS DISCUSSED BELOW UNDER "RISK
FACTORS" AND ELSEWHERE IN THIS QUARTERLY REPORT ON FORM 10-QSB ARE AMONG THOSE
FACTORS THAT IN SOME CASES HAVE AFFECTED OUR RESULTS AND COULD CAUSE THE ACTUAL
RESULTS TO DIFFER MATERIALLY FROM THOSE PROJECTED IN THE FORWARD-LOOKING
STATEMENTS.

The following discussion should be read in conjunction with the Condensed
Financial Statements and Notes thereto.

Overview/ Recent Developments

We are a developmental stage company, and have a very limited operating history
and no revenue to date.  Our prospects must be considered in light of the risks
and uncertainties encountered by companies in an early stage of development
involving new technologies and overcoming regulatory approval process
requirements before any revenue is possible.

We have experienced operating losses since our inception.  These losses have
resulted from the significant costs incurred in the development of our
technology and the establishment of our research and development facility.
Expenditures will increase in all areas in order to execute our business plan,
particularly in research and development and in gaining regulatory approval to
market our products in the U.S. and abroad.

In 2003, we experienced increased difficulty in raising outside capital.  This
difficulty continued through the third quarter of 2004.  Although research
continued in organ preservation, we were forced to suspend animal testing and
human infusion testing due to a lack of funds.  Our employees accepted a
temporary 50% salary reduction in January 2004 to conserve cash, and several of
these employees as well as certain of our outside consultants elected to convert
a portion of their deferred compensation to shares of our common stock.  On
September 1, 2004, we restored all employee salaries; however, employees
received 50% of their salaries in cash and 50% in shares or restricted common
stock as an accrual.  In March 2005, we made the decision to pay all of these
accrued salaries in cash. In February 2005, we changed our overall compensation
structure to reduce recurring payroll expenses in non-critical areas in order to
provide additional resources for the completion of our scientific objectives.

<page>2

During the year ended December 31, 2004, we pursued various alternatives for
raising capital, including but not limited to transactions with Dutchess Private
Equities Fund II ("Dutchess"), Langley Park Investments PLC ("Langley") and Pini
Ben David ("Ben David").  In 2004 and 2005, we also raised funds through the
sales of our capital stock through Regulation S under the Securities Act.  In
October 2005, we entered into an agreement with Ascendiant Capital to assist in
the capital-raising process (see "Liquidity and Capital Resources" below for
detailed descriptions of all of the above transactions). To date, we continue to
seek alternative sources for capital.

Our principal business objective is to develop and provide economical, non-toxic
methods of extending the shelf life and improving the quality of blood platelets
and other biological material.  We have been successful in preserving blood
platelets for ten days under refrigeration while maintaining cell structure and
some morphology, which has never been done before to our knowledge.  We had
originally contemplated submitting our findings to the FDA in the first half of
2003; however, additional pre-human infusion tests were necessary to address
certain aspects of our findings. We believe that we have now satisfactorily
resolved all issues raised by these findings, and resumed the process of our
human infusion tests in February 2005.  Some delays have been encountered at the
centers conducting the tests as it was necessary for the centers to repeat our
in-vitro (test tube) tests prior to proceeding to the actual human tests. In one
of the centers, internal approval for starting the pre-human infusion studies
had to be secured, which is now in place. We currently anticipate that these
tests will be completed within the next four to six months.

We began research on kidney preservation in 2002 and have developed what we
believe is a solution that will operate under refrigerated temperature storage
conditions for over 30 hours, allowing organ preservation beyond current
capabilities.  In our most recent preliminary tests, we successfully
transplanted a rat kidney that had been frozen at a temperature of negative 80
degrees Centigrade for three months in our patent pending HBS sub-zero solution.
In October 2005, we successfully completed the initial phase of our survival
study of animals with transplanted kidneys preserved using our HBS organ
preservation solution, and were able to preserve a rat's kidney at negative 196
degrees Centigrade for up to 5 days while maintaining some functionality when
transplanted back into the animal, exhibited by urine production.  We previously
preserved rats' kidneys at negative 20 and negative 80 degrees Centigrade. We
will continue to conduct further tests on a larger animal sample size, and
conduct histology and survival studies as well.  Our goal is to extend the
kidney shelf life for up to 72 to 96 hours at above freezing temperatures and
even longer at sub-zero temperatures.  We believe that the extended shelf life
should enable better matching of donor kidneys to recipients.

<page>3

In July 2002, we received our first patent on our technology and methodology for
preserving blood platelets.  We filed a provisional patent application in
September 2001 to cover our platelet preservation methods.  In August 2003, we
filed another patent application covering improved platelet preservation
methods.  We will seek strategic alliances with companies that have the
capability to provide technical and clinical expertise as well as financial and
marketing expertise to leverage our current expertise in these areas.

In addition to our attempts to raise outside capital, we have pursued
opportunities to acquire existing products and businesses that currently
produce, or have the potential to produce, revenue.  In September 2003 we signed
a binding letter of intent to acquire all rights to a cream product with
potential skin healing and antibacterial properties.  The purpose of the
acquisition is to develop a product to generate revenues while our blood
platelet preservation technology is awaiting human infusion tests.  During 2004,
using minimal funding, we were able to reformulate the cream for better
appearance and use.  We then tested the reformulated cream for safety at an
independent laboratory, and received positive results.  We are now seeking a
business partner to produce and market the cream.  There is no guarantee that we
will be able to develop a marketable product based on the cream.  If we are able
to develop a marketable product, it will require additional research and
development as well as additional capital.  At this time, we do not have an
estimate of the time or the amount of funds that would be required to produce
and market such a product.

Results of Operations

THREE MONTHS ENDED SEPTEMBER 30, 2005 COMPARED WITH THREE MONTHS ENDED SEPTEMBER
30, 2004

Revenues.  We did not generate any revenue in either of the three-month periods
ended September 30, 2005 or 2004, and we have not generated revenues since our
inception in February 1998, as our focus to date has been on the research and
development of products.  We are a development stage company in the eighth year
of research and development activities, and do not anticipate receiving revenue
until we complete product development and clinical testing.

General and Administrative Expenses. Total general and administrative expenses
in the three months ended September 30, 2005 were $2,542,300, an increase from
$256,900 for the three months ended September 30, 2004.  The increase was due
primarily to a significant increase in public relations expenses to $2,084,300
for the three months ended September 30, 2005.  We had no public relations
expenses for the comparable period in 2004. These expenses stem from a public
relations agreement with Abernathy Mendelson & Associates ("Abernathy"),
pursuant to which we provide shares of common stock as payment for advertising
and promotional services.  Our original agreement with Abernathy, entered into
in March 2005 and subsequently amended in April 2005, provided that Abernathy
would promote us to the investment community and the general public through
press releases and other communications, all of which we must approve in
advance.  The term of the Abernathy agreement was six months, subject to prior
termination.  In consideration for the public relations services, we were
required to issue compensation shares to Abernathy equal to 30% of the increase
in buy volume of our common stock that was directly attributable to Abernathy.
In addition, we were required to issue bonus shares to Abernathy equal to 10% of
the increase in buy volume in the event that the sales price of our common stock
as quoted on the OTC Bulletin Board equaled or exceeded $0,25 per share.  We
were required to place an aggregate of 3,000,000 free trading shares of common
stock in escrow in advance of the services under the Abernathy agreement.
Through September 30, 2005, we issued an aggregate of 1,580,245 of these shares
of common stock to
Abernathy.

<page>4

In June 2005, we entered into a second agreement with Abernathy for additional
public relations consulting services and issued an additional 750,000 shares of
free trading shares of common stock for these services, valued at $247,500. We
also became obligated to issue an additional 899,500 shares to Abernathy as a
bonus under this second agreement. These shares will be issued at a future
date.

The increase in general and administrative expenses was also partly due to an
increase in stock-based compensation in the three months ended September 30,
2005 to $167,900, from $54,500 for the three months ended September 30, 2005.
From time to time, our staff has worked for under market rate compensation or
has had to accrue pay for extended periods of time when financing was not
available.  We have granted stock options to certain employees in partial
consideration for salary reductions, and certain employees have elected to
receive stock in lieu of compensation.  Our employees accepted a temporary 50%
salary reduction in January 2004 to conserve cash, and several of these
employees as well as certain of our outside consultants elected to convert a
portion of their deferred compensation to shares of our common stock.  On
September 1, 2004, we restored all employee salaries; however, employees
received 50% of their salaries in cash and 50% in shares or restricted common
stock as an accrual.  We subsequently made the decision to pay all of these
accrued salaries in cash.  In February 2005, we changed our overall compensation
structure to reduce recurring payroll expenses in non-critical areas in order to
provide additional resources for the completion of our scientific objectives.

We also experienced an increase in other general and administrative expenses to
$290,100 for the three months ended September 30, 2005 from $202,400 for the
comparable period in 2004.  This increase was due to increases in legal and
professional fees and other expenses due to the obligations of being a public
company.

Research and Development.  Our research and development expenses were $42,300
for the three months ended September 30, 2005, equal to the amount for the
comparable period in 2004.    In 2003, we suspended human infusion studies and
animal testing pending receipt of funding, and this suspension remained in place
for all of 2004 and the first half of the first quarter of fiscal 2005.  In
February 2005, however, we resumed our infusion studies and organ preservation
research and in the near future plan to double the number of animal organ
preservation experiments as compared to the current schedule.   We believe that
recent payroll reductions should allow us to maintain and possibly accelerate
our scientific program.

Sales and Marketing Expenses.  We had no sales and marketing expenses for the
three months ended September 30, 2005, a decrease from $35,500 for the
comparable period in 2004.    We recently eliminated payroll in the sales and
marketing area in order to give priority to the completion of our scientific
objectives - to complete human infusion studies for platelets and move closer to
human testing utilizing our organ preservation technology.

<page>5

Forgiveness of Debt.  In the three months ended September 30, 2005, we recorded
forgiveness of debt from a vendor in the amount of $80,100, based upon the
vendor's realization of additional funds from the sale of common stock issued in
satisfaction of that debt.  No such forgiveness was recorded in the comparable
period in 2004.

Interest Income and Expense.  We did not receive interest income or incur
interest expense during the three months ended September 30, 2005.  During the
comparable period in 2004, we incurred interest expense of $100, due primarily
to interest on certain accrued wages, vacation and accounts payable converted to
common stock.

Net Loss.  As a result of the foregoing factors, our net loss increased to
$2,504,500 for the three months ended September 30, 2005 from a net loss of
$334,800 for the three months ended September 30, 2004.  Our net loss per share
increased to $0.04 for the three months ended September 30, 2005 from $0.01 for
the comparable period in 2004.

NINE MONTHS ENDED SEPTEMBER 30, 2005 COMPARED WITH NINE MONTHS ENDED SEPTEMBER
30, 2004

Revenues.  We did not generate any revenue in either of the nine-month periods
ended September 30, 2005 or 2004, and we have not generated revenues since our
inception in February 1998, as our focus to date has been on the research and
development of products.  We are a development stage company in the sixth year
of research and development activities, and do not anticipate receiving revenue
until we complete product development and clinical testing.

General and Administrative Expenses. Total general and administrative expenses
in the nine months ended September 30, 2005 were $4,441,700, an increase from
$797,600 for the nine months ended September 30, 2004.  This increase was
primarily due to an increase in public relations expenses, which equaled
$3,202,600 for the nine months ended September 30, 2005.  We did not incur
public relations expenses for the comparable period in 2004. The public
relations expenses were derived primarily from the Abernathy agreement described
above.  We also experienced an increase in stock-based compensation to $450,300
for the nine months ended September 30, 2005 from $329,700 for the comparable
period in 2004, due to the change in our overall compensation structure
described above.  In addition, we had an increase in other general and
administrative expenses, from $467,900 for the nine months ended September 30,
2004 to $788,800 for the nine months ended September 30, 2005.  This increase
was due to increases in legal and professional fees and other expenses due to
the obligations of being a public company.

<page>6

Research and Development.  Our research and development expenses were $138,300
for the nine months ended September 30, 2005, a decrease from $154,600 for the
comparable period in 2004.  This decrease was primarily due to a slowdown in
research and development activity beginning in the fourth quarter of 2003,
reflecting our funding shortfall.

Sales and Marketing Expenses.  Our sales and marketing expenses for the nine
months ended September 30, 2005 equaled $25,400, a decrease from $93,900 for the
comparable period in 2004.  The decrease is due to reductions of payroll
expenses in order to give priority to our scientific objectives, as set forth
above.

Interest Income and Expense.  We did not incur any interest expense during the
nine months ended September 30, 2005, as compared to interest expense of
$366,200 for the same period in 2004. This increase was due primarily to
interest on certain accrued wages, vacation and accounts payable converted to
common stock during the first quarter of 2004.

Net Loss.  As a result of the foregoing factors, our net loss increased to
$4,526,900 for the nine months ended September 30, 2005 from a net loss of
$1,412,300 for the nine months ended September 30, 2004.  Our net loss per share
was $0.08 for the nine months ended September 30, 2005, and $0.04 for the
comparable period in 2004.

Liquidity and Capital Resources

In the nine months ended September 30, 2005, we continued to spend cash to fund
our operations.  Cash used by operating activities for the nine months ended
September 30, 2005 equaled $783,600, and consisted principally of our net loss
of $4,526,900, depreciation of $700, and an increase in accounts payable of
$160,300, offset by $450,300 provided by stock based compensation, a decrease in
accrued liabilities of $600 and an increase in pre-paid expenses of $6,200. For
the comparable period in 2004, cash used by operating activities equaled
$571,300 and consisted of our net loss of $1,412,300, offset by $365,300
provided by interest expense paid in shares of our common stock, $329,700
provided by stock based compensation, an increase in accounts payable of
$90,600, a decrease of $14,100 in prepaid expenses and other assets, $1,100 in
depreciation and an increase in other liabilities of $40,200.

There was $11,000 used in investing activities for the nine months ended
September 30, 2005, due to the purchase of a special freezer for conducting our
organ preservation experiments.  We did not utilize or receive cash from
investment activities during the comparable period of 2004.

<page>7

Cash flow from financing activities for the nine months ended September 30, 2005
produced a net increase in cash of $218,600, consisting principally of $795,100
from the issuance of common stock, offset by an increase of $219,100, in
shareholder payables. Cash flow from financing activities for the nine months
ended September 30, 2004 produced a net increase in cash of $564,200 which
resulted from $252,100 in proceeds from the issuance of common stock and a
$312,100 decrease in shareholder payables.

As of September 30, 2005, we had cash and cash equivalents amounting to $60,100,
a decrease of $218,600 from the balance at December 31, 2004. Our working
capital deficit increased to $844,100 at September 30, 2005 from $406,700 at
June 30, 2005 and $313,800 at December 31, 2004.  The increase in this deficit
is from the resources used in our operations, as explained above.  There are no
material commitments for capital expenditures at September 30, 2005.

Our operating plan for calendar year 2005 is focused on continued development of
our products. It is our estimate that a cash requirement of $2.5 million is
required to support this plan for the next twelve months.  Since our inception,
we have financed our operations through private and public equity placements
During the year ended December 31, 2004, we received an aggregate of $999,400
from the issuance of common stock, compared to an aggregate of approximately
$905,400 received in the year ended December 31, 2003 and approximately
$2,151,300 received in the year ended December 31, 2002.  During the first nine
months of 2005, we have received an aggregate of $552,700 from the issuance of
common stock, including approximately $16,800 from our agreement with Dutchess.
We are actively seeking additional funding.  Once we receive the required
additional financing, we anticipate continued growth in our operations and a
corresponding growth in our operating expenses and capital expenditures.  We do
not anticipate any revenue from operations for the next two or three years.
Therefore, our success will be dependent on funding from private placements of
equity securities.  Although we have entered into certain agreements with
Dutchess, there can be no assurance that we will be successful in raising any
capital pursuant to this agreement.  At the present time, we have no other
agreements or arrangements for any private placements.

In 2003, we experienced increased difficulty in raising outside capital.  This
difficulty continued through the third quarter of 2004.  Although research
continued in organ preservation, we were forced to suspend animal testing and
human infusion testing due to a lack of funds.  Our employees accepted a
temporary 50% salary reduction in January 2004 to conserve cash, and several of
these employees as well as certain of our outside consultants elected to convert
a portion of their deferred compensation to shares of our common stock.  On
September 1, 2004, we restored all employee salaries; however, employees
received 50% of their salaries in stock and 50% in shares or restricted common
stock.  In February 2005, we changed our overall compensation structure to
reduce recurring payroll expenses in non-critical areas in order to provide
additional resources for the completion of our scientific objectives.  In March
2005, we made the decision to pay all of the accrued salaries in cash instead of
in stock.

<page>8

We are in the eighth year of research and development, with an accumulated loss
during the development stage of $19,185,500.  As of September 30, 2005, we are
uncertain as to the completion date of our research and development, or if
products will ever be completed as a result of this research and development
activity.  We anticipate that the funds spent on research and development
activities will need to increase prior to completion of a product. Additionally,
we may not be able to secure funding in the future necessary to complete our
intended research and development activities.

These conditions give rise to substantial doubt about our ability to continue as
a going concern. Our financial statements do not include adjustments relating to
the recoverability and classification of reported asset amounts or the amount
and classification of liabilities that might be necessary should we be unable to
continue as a going concern.  Our continuation as a going concern is dependent
upon our ability to obtain additional financing from the sale of our common
stock, as may be required, and ultimately to attain profitability.

The report of our independent certified public accountants, included in our most
recent Annual Report on Form 10-KSB, contains a paragraph regarding our ability
to continue as a going concern.

During the year ended December 31, 2004, we pursued various alternatives for
raising capital.  We entered into the Investment Agreement with Dutchess
effective September 28, 2004.  Pursuant to the terms of the Investment
Agreement, we may offer, through a series of puts, and Dutchess must purchase
from time to time, up to a maximum of 38,000,000 shares of our common stock,
provided that Dutchess shall not be required to purchase shares of our stock
with an aggregate purchase price in excess of $5,000,000.  The purchase price of
shares purchased under the Investment Agreement shall be equal to 95% of the
lowest closing "best bid" price (the highest posted bid price) of the common
stock during the five consecutive trading days immediately following the date of
our notice to Dutchess of our election to put shares pursuant to the Investment
Agreement.  The dollar value that we will be permitted to put pursuant to the
Investment Agreement will be either: (A) 200% of the average daily volume in the
US market of the common stock for the ten trading days prior to the notice of
our put, multiplied by the average of the three daily closing bid prices
immediately preceding the date of the put, or (B) $10,000.  No single put can
exceed $1,000,000.  We filed a registration statement on Form SB-2 in July 2004
to register for resale an aggregate of 38,000,000 shares of common stock
issuable under the Investment Agreement; this registration statement was
declared effective on August 23, 2004.  In April 2005, we issued 30,000 shares
of common stock to Dutchess pursuant to our first put under the Investment
Agreement, and received approximately $16,800 in proceeds.  In October 2005, we
issued 108,605 shares of common stock to Dutchess pursuant to our sixth put
under the Investment Agreement, and received proceeds of $65,000.

<page>9

In July 2004, we entered into the Stock Purchase Agreement, whereby we would
sell shares of our restricted common stock for shares in Langley, a London-based
institutional investment trust.  Langley was formed in February 2004 to invest
in a diverse portfolio of U.S. small-cap companies (defined by Langley
management as those public companies having a market capitalization of less than
U.K. $100 million).  Although Langley's investments are not limited to specific
sectors, it has concentrated on mining, oil and gas, energy-related and
technology companies since it commenced operations in February 2004.  Langley's
stated investment objective is to achieve long-term capital growth.  The Langley
ordinary shares are registered as a unit investment trust on the London Stock
Exchange ("LSE").  The trading symbol for the ordinary shares is LSE:LPI.  The
Langley Investment Trust consists of a portfolio of the common stock of 23 U.S.
publicly traded small cap companies.

Langley purchased 7,000,000 shares of our restricted stock at a price of
$930,999, or approximately $0.13 per share.  The shares issued to Langley
constituted 17.9% of our outstanding common stock at July 31, 2004.  In lieu of
cash, Langley issued to us an aggregate of 512,665 Langley ordinary shares at a
price of U.K. $1.00 per share (one British Pound Sterling = US $1.8160 on July
30, 2004).  The Langley ordinary shares issued to us constituted less than one
percent of Langley's issued and outstanding ordinary shares at September 30,
2004.  The total sales price of $930,999 was determined by multiplying the
7,000,000 shares by the average of the closing bid price of our common stock
during the ten trading days preceding the date of the Agreement.  The 512,665
shares in Langley received as consideration was calculated by dividing the total
sales price by the conversion rate of the British Pound Sterling to the U.S.
dollar as of the close of business on July 26, 2004.  Upon the closing of this
transaction, Langley and we were required to issue our respective shares into an
escrow account, whereby we could immediately liquidate up to 50% of the Langley
shares.  We and the other portfolio companies have received one-half of the
free-trading Langley ordinary shares sold to us under the Stock Purchase
Agreement.  The remaining 50% of the free-trading Langley ordinary shares will
be held in escrow for two years as a downside price protection against our
shares issued to Langley.  In the event of a decline in the market price of our
common stock at the end of two years, we will be required to sell to Langley the
amount of our Langley shares equal to (i) the original number of Langley shares
issued as consideration under the Stock Purchase Agreement multiplied by (ii)
the percentage decrease in the market price of our common stock.  If at the end
of the two-year period the trading price of our common stock falls below $0.065,
we will have to sell back to Langley all the escrowed Langley shares.  If at the
end of the trading period the trading price of our common stock is more than
$0.065 but less than $0.13, we will need to sell back to Langley only a
proportionate amount of our Langley ordinary shares.  We have no obligation to
register for resale our shares that are held by Langley.

<page>10

On November 14, 2005, Langley had a net asset value for its underlying portfolio
of U.K. $0.57 per ordinary share, or an aggregate net asset value of U.K.
$42,508,790 (U.S. $73,756,479, based on U.K. $1.00 = U.S. $1.735 on November 14,
2005).  Assuming that the downside protection (or "claw-back rights") had been
exercised by Langley, this would represent a net asset value per ordinary share
of U.K. $0.37, or an aggregate net asset value of U.K. $27,593,425 (U.S.
$47,869,223).  We had anticipated that the trust would traditionally trade at a
discount to its net asset value; however, the discount has been more significant
than we expected.  To date, due to the low trading price of the Langley stock on
the London Stock Exchange (U.K. $0.135 per ordinary share on November 14, 2005),
we have not sold any of our Langley ordinary shares.

The rights of holders of Langley ordinary shares are set forth in Langley's
Memorandum of Association.  In general, each holder of Langley ordinary shares
has one vote for every ordinary share held.  Unless Langley's directors decide
otherwise, a holder of ordinary shares may not vote, either personally or by
proxy, unless all calls and other amounts payable with respect to the ordinary
shares have been paid.  Holders of ordinary shares may receive dividends in
Langley as and when declared by the directors.  In the event of a liquidation of
Langley, holders of ordinary shares may receive their pro rata share of any
remaining assets.  In the event that Langley has more than one class of shares,
the rights of the holders of any one class of shares may be varied only with the
written consent of holders of three-fourths of the nominal value of the issued
shares of that class, or with the sanction of an extraordinary resolution passed
at a separate general meeting of such holders.

We considered a variety of possible financing options prior to entering into the
transaction with Langley.  In the past year, it has become more difficult for us
to effect equity placements on terms and conditions satisfactory to us and our
shareholders.  We were approached by a number of private investors who sought to
purchase common stock at significant discounts to market and other potential
investors who wanted to receive common stock in advance of forwarding
consideration for the stock to us.  None of these alternatives were acceptable
to management.  We selected Langley after due diligence on Langley and its
management, including but not limited to a review of a prior fund with similar
structure and investment strategies, assembled by the founders of Langley.

Effective October 28, 2004, we entered into the Loan Agreement with Ben David.
Ben David is not, and has not been during the past two years, an affiliate of us
or any of our current or former affiliates.  The Loan Agreement called for Ben
David to loan us an aggregate of $2,300,000 euros (the "Loan").  The Loan was to
bear interest at the rate of three percent per annum, with payments of interest
due monthly and all principal plus accrued but unpaid interest due and payable
on November 1, 2007.  Repayment of the Loan was secured by 23,000,000 shares of
our common stock (the "Shares") issuable pursuant to Regulation S under the
Securities Act.  Pursuant to the Loan Agreement and an Escrow Agreement between
Ben David and us, a certificate representing the Shares (the "Certificate"),
containing a legend restricting transfer, was delivered to Ben David to hold
until funds for repayment of the Loan were delivered to Ben David to hold until
funds for repayment of the Loan were delivered to the escrow agent.  We believe
that the parties intended that when the loan funds were delivered by Ben David
to the escrow agent, Ben David would also deliver the stock certificate to the
escrow agent who would disburse the funds and the Certificate to the appropriate
parties.  The Loan Agreement also provided that it would terminate, and the
Shares immediately returned to us, in the event that the Loan funds were not
delivered to us by the 15th calendar day following the date of the Loan
Agreement (November 13, 2004).  Pursuant to Ben David's request, we extended the
date for receipt of Loan funds to December 23, 2004 and exchanged the
Certificate for three Certificates (one to Ben David and one to each of two
affiliates); however, no Loan funds were received by that date.  On January 11,
2005, we instructed our transfer agent to cancel the Certificates, and notified
Ben David that the Loan Agreement was cancelled and of no further force or
effect.  We did not incur any early termination penalties in connection with the
cancellation of the Loan Agreement.

<page>11

In the second quarter of 2005, it came to our attention that shares of our
common stock (the "Reg S Stock") may have been sold in Germany without our
authorization, possibly in connection with the canceled Ben David certificates.
In order to halt these unauthorized issuances, we commenced an exchange offer
(the "Offer") in July 2005 to exchange one share of our common stock (the "New
Stock") for each share of Reg S Stock outstanding before or upon the de-listing
date (the "Record Date") when the Reg S Stock is no longer tradable.   The Offer
covers 10,000,000 shares of our common stock, and is intended to reduce our
potential liability for the unauthorized issuances.  Each share of New Stock
will be registered no later than nine months from the initial date of the Offer
for trading on the OTC Bulletin Board market.  The Offer expires on December 29,
2005.  Any shares of Reg S Stock not tendered for exchange by December 29,
2005, will no longer be exchangeable for New Stock and will no longer be
tradable on any German stock exchange.  To date, holders of an aggregate of
3,773,082 shares have indicated an intent to participate in the Offer; of these,
holders of an aggregate of 2,701,247 shares have forwarded certificates and
required documents.

In March 2005, we entered into an agreement with Abernathy which was
subsequently amended in April 2005).  The Abernathy agreement provided that
Abernathy would promote us to the investment community and the general public
through press releases and other communications, all of which we must approve in
advance.  The term of the Abernathy agreement was six months, subject to prior
termination.  In consideration for the public relations services, we were
required to issue compensation shares to Abernathy equal to 30% of the increase
in buy volume of our common stock that was directly attributable to Abernathy.
In addition, we were required to issue bonus shares to Abernathy equal to 10% of
the increase in buy volume in the event that the sales price of our common stock
as quoted on the OTC Bulletin Board equaled or exceeded $0,25 per share.  We
were required to place an aggregate of 3,000,000 free trading shares of common
stock in escrow in advance of the services under the Abernathy agreement.
Through September 30, 2005, we issued an aggregate of 1,580,245 of these shares
of common stock to Abernathy.

In June 2005, we entered into a second agreement with Abernathy for
additional public relations consulting services and issued an additional 750,000
shares of free trading shares of common stock for these services. We also became
obligated to issue an additional 899,500 shares to Abernathy as a bonus under
this second agreement.  These shares will be issued at a future date.

In October 2005, we entered into an agreement with Ascendiant Securities, LLC
("Ascendiant") providing that Ascendiant would act on a best-efforts basis as
our financial advisor and non-exclusive placement agent in connection with the
structuring, issuance and sale of our debt and equity securities for financing
purposes.  The agreement, which has a term of six months, requires us to pay
Ascendiant a cash success fee and warrants for completed transactions that we
approve.  The  success fee is equal to ten percent of the gross proceeds from
the sale of our securities; in addition, for transactions generating gross
proceeds of $2,000,000 or more, we must issue Ascendiant 175,000 shares of our
restricted common stock.  To date, no transactions have been presented to us by
Ascendiant.

<page>12

Critical Accounting Policies

The preparation of financial statements and related disclosures in conformity
with accounting principles generally accepted in the United States requires us
to make judgments, assumptions and estimates that affect the amounts reported.
Note 1 of Notes to Financial Statements describes the significant accounting
policies used in the preparation of the financial statements. Certain of these
significant accounting policies are considered to be critical accounting
policies, as defined below.

A critical accounting policy is defined as one that is both material to the
presentation of our financial statements and requires management to make
difficult, subjective or complex judgments that could have a material effect on
our financial condition and results of operations. Specifically, critical
accounting estimates have the following attributes: 1) we are required to make
assumptions about matters that are highly uncertain at the time of the estimate;
and 2) different estimates we could reasonably have used, or changes in the
estimate that are reasonably likely to occur, would have a material effect on
our financial condition or results of operations.

Estimates and assumptions about future events and their effects cannot be
determined with certainty. We base our estimates on historical experience and on
various other assumptions believed to be applicable and reasonable under the
circumstances. These estimates may change as new events occur, as additional
information is obtained and as our operating environment changes.  These changes
have historically been minor and have been included in the consolidated
financial statements as soon as they became known. Based on a critical
assessment of our accounting policies and the underlying judgments and
uncertainties affecting the application of those policies, management believes
that our financial statements are fairly stated in accordance with accounting
principles generally accepted in the United States, and present a meaningful
presentation of our financial condition and results of operations.

In preparing our financial statements to conform to accounting principles
generally accepted in the United States, we make estimates and assumptions that
affect the amounts reported in our financial statements and accompanying notes.
These estimates include useful lives for fixed assets for depreciation
calculations and assumptions for valuing options and warrants. Actual results
could differ from these estimates.

We consider that the following are critical accounting policies:

Research and Development Expenses

All research and development costs are expensed as incurred. The value of
acquired in-process research and development is charged to expense on the date
of acquisition. Research and development expenses include, but are not limited
to, payroll and personnel expense, lab supplies, preclinical studies, raw
materials to manufacture our solution, manufacturing costs, consulting, legal
fees and research-related overhead. Accrued liabilities for raw materials to
manufacture our solution, manufacturing costs, and patent legal fees are
included in accrued liabilities and included in research and development
expenses.

<page>13

Employee Stock Plans

As permitted by SFAS No. 123, "Accounting for Stock-Based Compensation," we
elected to continue to apply the provisions of APB Opinion No. 25, "Accounting
for Stock Issued to Employees," and related interpretations in accounting for
our employee stock option and stock purchase plans. We are generally not
required under APB Opinion No. 25 and related interpretations to recognize
compensation expense in connection with our employee stock option and stock
purchase plans. We are required by SFAS No. 123 to present, in the Notes to
Financial Statements, the pro forma effects on reported net income and earnings
per share as if compensation expense had been recognized based on the fair value
method of accounting prescribed by SFAS No. 123.

Risk Factors

Our business, financial condition or results of operations could be materially
and adversely affected by any of the following risks:

WE HAVE A HISTORY OF LOSSES, AND OUR INDEPENDENT CERTIFIED PUBLIC ACCOUNTANTS
HAVE RAISED DOUBTS ABOUT OUR ABILITY TO CONTINUE AS A GOING CONCERN.

Since our inception in 1998, we have incurred substantial losses from
operations, resulting primarily from costs related to research and development
and building our infrastructure.  Because of our status as a development stage
company and the need to conduct additional research and development prior to
introducing products and services to the market, we expect to incur net losses
for the foreseeable future.  If our growth is slower than we anticipate or our
operating expenses exceed our expectations, our losses will be significantly
greater.  We may never achieve profitability.  Primarily as a result of these
recurring losses, our independent certified public accountants modified their
report on our December 31, 2004 financial statements to include an uncertainty
paragraph wherein they expressed substantial doubt about our ability to continue
as a going concern.

We are in the eighth year of research and development, with an accumulated loss
during the development stage of $19,185,500.  We currently do not know when our
research and development will be completed, or if a product will ever result
from this research and development activity.  We anticipate that the funds spent
on research and development activities will need to increase significantly prior
to completion of research and development and commercialization of a product.
Additionally, we may not be able to secure funding in the future necessary to
complete our intended research and development activities.  In 2003, we scaled
back our research and development activities significantly, due to our lack of
capital.  In February 2005, we resumed certain research and development projects
on a limited basis, but cannot predict when we will be able to maintain a
complete research and development program.

<page>14

These conditions give rise to substantial doubt about our ability to continue as
a going concern. Our financial statements do not include adjustments relating to
the recoverability and classification of reported asset amounts or the amount
and classification of liabilities that might be necessary should we be unable to
continue as a going concern.  Our continuation as a going concern is dependent
upon our ability to obtain additional financing from the sale of our securities,
as may be required, and ultimately to attain profitability.

WE REQUIRE IMMEDIATE ADDITIONAL CAPITAL.

Our operating plan for calendar year 2005 is focused on development of our
products. It is our estimate that a cash requirement of $2.5 million is required
to support this plan for the next twelve months.  During the year ended December
31, 2004, we received an aggregate of $999,400 from the issuance of common
stock, compared to an aggregate of approximately $905,400 received in the year
ended December 31, 2003 and approximately $2,151,300 received in the year ended
December 31, 2002.  During the nine months ended September 30, 2005, we received
an aggregate of $795,100 from the issuance of common stock, including $225,600
from our agreement with Dutchess.  We are actively seeking additional funding.
There can be no assurance that the required additional financing will be
available on terms favorable to us or at all.  Although we have entered into
certain agreements with Dutchess, there can be no assurance that we will be
successful in raising any capital pursuant to this agreement.

Obtaining capital will be challenging in a difficult environment, due to the
downturn in the United States economy and current world instability.  We
currently have no commitments for any funding, and there can be no assurance
that we will be able to obtain additional funding in the future from either debt
or equity financings, bank loans, collaborative arrangements or other sources on
terms acceptable to us, or at all.  If our human infusion studies are
successful, we believe that we will be able to obtain additional funding through
a license agreement with one or more of the potential strategic partners with
whom we have had discussions to date, thereby satisfying our financial needs for
at least 2006; there can be no assurance that we will achieve successful results
in our human infusion studies or that we can enter into a license agreement or
agreements providing adequate financing for 2005 and beyond.

<page>15

If adequate funds are not available or are not available on acceptable terms
when required, we may be required to significantly curtail our operations or may
not be able to fund expansion, take advantage of unanticipated acquisition
opportunities, develop or enhance services or products or respond to competitive
pressures. Such inability could have a material adverse effect on our business,
results of operations and financial condition.  If additional funds are raised
through the issuance of equity or convertible debt securities, the percentage
ownership of our shareholders will be reduced, shareholders may experience
additional dilution, and such securities may have rights, preferences and
privileges senior to those of our common stock.

OUR CHIEF EXECUTIVE OFFICER IS THE SUBJECT OF SEC AND JUSTICE DEPARTMENT
PROCEEDINGS FOR SECURITIES FRAUD.

On August 7, 2002, the United States Attorney for the Eastern District of New
York and the Securities and Exchange Commission announced that they were
bringing securities fraud charges against Harry Masuda, our Chief Executive
Officer, for allegedly paying an unregistered broker an undisclosed commission
in a 1999 and 2000 private placement.  The allegations generally charge Mr.
Masuda with the failure to adequately disclose to investors in this private
placement a commission agreement with Larry Bryant, an unlicensed broker-dealer.
Remedies sought in these proceedings include criminal penalties and a bar from
service as an officer or director of a publicly-traded company.  The SEC also
brought securities fraud charges against us for the same transactions.  Although
we believe that the charges are unwarranted, and that the issues involved in
this matter were resolved over two years ago to the full satisfaction of all
investors, there can be no assurance that Mr. Masuda will be able to continue to
serve as our Chief Executive Officer in the event that the Securities and
Exchange Commission receives the remedies that it seeks.  In January 2005, the
United States Government and Mr. Masuda entered into a deferred prosecution
agreement which should lead to a dismissal of all charges against Mr. Masuda at
the end of the 18-month deferred prosecution term.   The civil case against us
has been stayed at the request of the U.S. Attorney pending completion of the
deferred prosecution term.

WE ARE A DEVELOPMENT STAGE COMPANY, AND HAVE A LIMITED OPERATING HISTORY ON
WHICH TO EVALUATE OUR POTENTIAL FOR FUTURE SUCCESS.

We are a development stage company, and have yet to produce or sell any products
or services.  We have only a limited operating history upon which you can
evaluate our business and prospects, and have yet to develop sufficient
experience regarding actual revenues to be received from our products and
services.  You must consider the risks and uncertainties frequently encountered
by early stage companies in new and rapidly evolving markets.  If we are
unsuccessful in addressing these risks and uncertainties, our business, results
of operations and financial condition will be materially and adversely affected.

<page>16

OUR FUTURE REVENUES ARE UNPREDICTABLE AND OUR QUARTERLY OPERATING RESULTS MAY
FLUCTUATE SIGNIFICANTLY.

We have a very limited operating history, and have no revenue to date. We cannot
forecast with any degree of certainty whether any of our products or services
will ever generate revenue or the amount of revenue to be generated by any of
our products or services. In addition, we cannot predict the consistency of our
quarterly operating results. Factors which may cause our operating results to
fluctuate significantly from quarter to quarter include:

-  our ability to attract new and repeat customers;

-  our ability to keep current  with  the evolving requirements of our target
   market;

-  our ability to protect our proprietary technology;

-  the ability of our  competitors to offer new or enhanced products or
   services; and

-  unanticipated  delays or cost  increases  with  respect to research and
   development.

Because of these and other factors, we believe that quarter-to-quarter
comparisons of our results of operations are not good indicators of our future
performance.  If our operating results fall below the expectations of securities
analysts and investors in some future periods, then our stock price may decline.

ESTABLISHING OUR REVENUES AND ACHIEVING PROFITABILITY WILL DEPEND ON OUR ABILITY
TO DEVELOP AND COMMERCIALIZE OUR PRODUCTS.

Much of our ability to establish revenues and to achieve profitability and
positive cash flows from operations will depend on the successful introduction
of our products in development.  Products based on our technologies will
represent new methods of treatment and preservation. Our prospective customers,
including blood banks, hospitals and clinics, will not use our products unless
they determine that the benefits provided by these products are greater than
those available from competing products.  Even if the advantage from our planned
products is clinically established, prospective customers may not elect to use
such products for a variety of reasons.

We may be required to undertake time-consuming and costly development activities
and seek regulatory clearance or approval for new products. The completion of
the development and commercialization of any of our products under development
remains subject to all of the risks associated with the commercialization of new
products based on innovative technologies, including unanticipated technical or
other problems, manufacturing difficulties and the possible insufficiency of the
funds allocated for the completion of such development.

<page>17

WE MAY NOT BE ABLE TO COMPETE SUCCESSFULLY.

As a development stage company, we are entering a biological material
preservation market that is presently addressed by large companies with
extensive financial resources.  Those companies include DuPont and Baxter, among
others.  Additionally, smaller companies with which we may compete include
LifeCell Corporation for platelet preservation, Cerus for viral inactivation of
platelets and other blood products and Cryo Life for preserving heart valves by
cryo-preservation. These companies are active in research and development of
biological material preservation.  We have limited funds with which to develop
products and services.  These companies are active in research and development
of biological material preservation, and we do not know the current status of
their development efforts.  Most of the above competitors have significantly
greater financial resources, technical expertise and managerial capabilities
than we currently possess.

WE MAY FAIL TO OBTAIN GOVERNMENT APPROVAL OF OUR PROCESSES

The FDA regulates the commercial distribution and marketability of medical
solutions and equipment.  In the event that we determine that these regulations
apply to our proposed products, we will need to obtain FDA approval for such
distribution.  The process of obtaining FDA approval may be expensive, lengthy
and unpredictable.  We have not developed our products to the level where these
approval processes can be started.  We do not know if such approval could be
obtained in a timely fashion, if at all.  In the event that we do not receive
any required FDA approval for certain products, we would not be able to sell
such products in the United States.

The regulation of our processes and products outside the United States will vary
by country.  Noncompliance with foreign country requirements may include some or
all of the risks associated with noncompliance with FDA regulation as well as
other risks.

ACTS OF TERRORISM, RESPONSES TO ACTS OF TERRORISM AND ACTS OF WAR MAY IMPACT OUR
BUSINESS AND OUR ABILITY TO RAISE CAPITAL.

Future acts of war or terrorism, national or international responses to such
acts, and measures taken to prevent such acts may harm our ability to raise
capital or our ability to operate, especially to the extent we depend upon
activities conducted in foreign countries, such as Russia where we currently
perform research and development.  In addition, the threat of future terrorist
acts or acts of war may have effects on the general economy or on our business
that are difficult to predict.  We are not insured against damage or
interruption of our business caused by terrorist acts or acts of war.

<page>18

WE MAY FAIL TO ESTABLISH AND MAINTAIN STRATEGIC RELATIONSHIPS.

We believe that the establishment of strategic partnerships will greatly benefit
the growth of our business, and we intend to seek out and enter into strategic
alliances.  We may not be able to enter into these strategic partnerships on
commercially reasonable terms or at all.  Even if we enter into strategic
alliances, our partners may not attract significant numbers of customers or
otherwise prove advantageous to our business.   Our inability to enter into new
distribution relationships or strategic alliances could have a material and
adverse effect on our business.

SHARES ELIGIBLE FOR FUTURE SALE BY OUR CURRENT STOCKHOLDERS MAY ADVERSELY AFFECT
OUR STOCK PRICE.

To date, we have had a very limited trading volume in our common stock.  As long
as this condition continues, the sale of a significant number of shares of
common stock at any particular time could be difficult to achieve at the market
prices prevailing immediately before such shares are offered.  In addition,
sales of substantial amounts of common stock, including shares issued upon the
exercise of outstanding options and warrants, under Securities and Exchange
Commission Rule 144 or otherwise could adversely affect the prevailing market
price of our common stock and could impair our ability to raise capital at that
time through the sale of our securities.  A number of our employees and
consultants have elected to convert a portion of their compensation to shares of
our common stock, and these shares have been registered for resale to the
public.

OUR COMMON STOCK PRICE IS LIKELY TO BE HIGHLY VOLATILE; OUR COMMON STOCK IS
"PENNY STOCK".

The market price of our common stock is likely to be highly volatile as the
stock market in general, and the market for technology companies in particular,
has been highly volatile.  The trading prices of many technology companies'
stocks have recently been highly volatile and have recorded lows well below
historical highs.

Factors that could cause such volatility in our common stock may include, among
other things:

 -  actual  or  anticipated fluctuations in our quarterly operating results;

 -  announcements of  technological  innovations;

 -  changes  in  financial  estimates  by  securities  analysts;

 -  conditions  or  trends  in our industry;  and

 -  changes  in  the  market  valuations  of  other comparable companies.

<page>19

In addition, our stock is currently traded on the NASD O-T-C Bulletin Board and
it is uncertain that we will be able to successfully apply for listing on the
AMEX, the NASDAQ National Market, or the Nasdaq SmallCap Market in the
foreseeable future due to the trading price of our common stock, our working
capital and revenue history.  Failure to list our shares on the AMEX, the Nasdaq
National Market, or the Nasdaq SmallCap Market will impair the liquidity of our
common stock.

The Securities and Exchange Commission has adopted regulations which generally
define a "penny stock" to be any security that 1) is priced under five dollars,
2) is not traded on a national stock exchange or on NASDAQ, 3) may be listed in
the "pink sheets" or the NASD OTC Bulletin Board, 4) is issued by a company that
has less than $5 million in net tangible assets and has been in business less
than three years, or by a company that has under $2 million in net tangible
assets and has been in business for at least three years, or by a company that
has revenues of less than $6 million for three years.

Penny stocks can be very risky: penny stocks are low-priced shares of small
companies not traded on an exchange or quoted on NASDAQ.  Prices often are not
available.  Investors in penny stocks are often unable to sell stock back to the
dealer that sold them the stock.  Thus an investor may lose his/her investment.
Our common stock is a "penny stock" and thus is subject to rules that impose
additional sales practice requirements on broker/dealers who sell such
securities to persons other than established customers and accredited investors,
unless the common stock is listed on The Nasdaq SmallCap Market. Consequently,
the "penny stock" rules may restrict the ability of broker/dealers to sell our
securities, and may adversely affect the ability of holders of our common stock
to resell their shares in the secondary market.

SOME OF THE INFORMATION IN THIS QUARTERLY REPORT CONTAINS FORWARD-LOOKING
STATEMENTS.

Some of the information in this Quarterly Report contains forward-looking
statements that involve substantial risks and uncertainties. You can identify
these statements by forward-looking words such as "may", "will", "expect",
"intend", "anticipate", "believe", "estimate" and "continue" or similar words.
You should read statements that contain these words carefully because they:

 -  discuss  our  expectations  about  our  future performance;

 -  contain  projections of our future operating results or of our future
    financial condition; or

 -  state  other  "forward-looking"  information.

<page>20

We believe it is important to communicate our expectations to our shareholders.
There may be events in the future, however, that we are not able to predict
accurately or over which we have no control.  The risk factors listed in this
section, as well as any cautionary language in this Prospectus, provide examples
of risks, uncertainties and events that may cause our actual results to differ
materially from the expectations we describe in our forward- looking statements.
Before you invest in our common stock, you should be aware that the occurrence
of any of the events described in these risk factors and elsewhere in this
prospectus could have a material and adverse effect on our business, results of
operations and financial condition and that upon the occurrence of any of these
events, the trading price of our common stock could decline and you could lose
all or part of your investment.

ITEM 3.  CONTROLS AND PROCEDURES

Based on an evaluation conducted within 90 days prior to the filing date of this
Quarterly Report on Form 10-QSB, our Chief Executive Officer and acting Chief
Financial Officer concluded that we maintain effective disclosure controls and
procedures that ensure information required to be disclosed in our reports under
the Securities Exchange Act of 1934 is recorded, processed, summarized and
reported within the time periods specified in the SEC's rules and forms.
Specifically, the disclosure controls and procedures assure that information is
accumulated and communicated to our management, including our Chief Executive
Officer and acting Chief Financial Officer, as appropriate, to allow timely
decisions regarding required disclosure.  There have been no significant changes
in our internal controls or in other factors that could significantly affect
these controls subsequent to the date of management's evaluation.

PART II -- OTHER INFORMATION

ITEM 1.  LEGAL PROCEEDINGS.

Not applicable.

ITEM 2.  UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS.

Set forth in chronological order is information regarding shares of common stock
issued and options and warrants and other convertible securities granted by us
during the three months ended September 30, 2005.  Also included is the
consideration, if any, received by us for such shares, options and warrants, and
information relating to the section of the Securities Act of 1933, as amended
(the "Securities Act"), or the rule of the Securities and Exchange Commission,
under which an exemption from registration was claimed.

In the third quarter of 2005, we issued an aggregate of 5,300 shares of our
common stock to an investor in satisfaction of accounts payable totaling $1,700.
This issuance was made in reliance on Section 4(2) of the Securities Act, and
was made without general solicitation or advertising. The recipient was a
sophisticated investor with access to all relevant information necessary to
evaluate the investments, and who represented to us that the shares were being
acquired for investment purposes.

<page>21

In the third quarter of 2005, we issued an aggregate of 180,000 shares of our
common stock to investors for services with an aggregate value of $150,600.
These issuances were made in reliance on Section 4(2) of the Securities Act, and
were made without general solicitation or advertising. The recipients were
sophisticated investors with access to all relevant information necessary to
evaluate the investments, and who represented to us that the shares were being
acquired for investment purposes.

ITEM 3.  DEFAULTS UPON SENIOR SECURITIES.

Not applicable.

ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

Not applicable.

ITEM 5.  OTHER INFORMATION.

Not applicable.

ITEM 6.  EXHIBITS.

Exhibit No.	 Title of Exhibit
----------       ----------------
31.01	Rule 13a-14(a)/15d-14(a) Certification
32.01	Section 1350 Certification


SIGNATURES

In accordance with the requirements of the Exchange Act, the registrant caused
this report to be signed on its behalf by the undersigned thereunto duly
authorized.


HUMAN BIOSYSTEMS



Date: November 14, 2005

/s/ Harry Masuda
------------------
Harry Masuda
Chief Executive Officer


<page>22