FINAL AGENDA

FIFRA SCIENTIFIC ADVISORY PANEL (SAP)

OPEN MEETING

May 24-26, 2011

FIFRA SAP WEB SITE http://www.epa.gov/scipoly/sap/

OPP Docket Telephone: (703) 305-5805

Docket Number: EPA-HQ- OPP-2011-0284

U.S. Environmental Protection Agency

Conference Center - Lobby Level

One Potomac Yard (South Bldg.)

2777 S. Crystal Drive, Arlington, VA 22202

Integrated Approaches to Testing and Assessment Strategy: Use of New 

Computational and Molecular Tools 

Please note that all times are approximate (see note at end of Agenda).

Tuesday, May 24, 2011

8:30 A.M. Opening of Meeting and Administrative Procedures

Dr. Fred Jenkins, Designated Federal Official, Office of Science Coordination and 

Policy, EPA

8:35 A.M. Introduction and Identification of Panel Members

Dr. Kenneth Portier, Chair, FIFRA Scientific Advisory Panel

8:40 A.M. Welcome and Opening Remarks

Dr. Steven Bradbury, Director, Office of Pesticide Programs (OPP), EPA

9:00 A.M. OPP’s Vision for an Integrated Approach to Testing and Assessment

Dr. John (Jack) R. Fowle III, Deputy Director, Health Effects Division, OPP, EPA

Partnership with ORD to Build a Scientific Foundation for the Vision

9:45 A.M. EPA’s Chemical Safety for Sustainability Research Program

Dr. Elaine Francis, National Program Director for Pesticides and Toxics 

Research, ORD, EPA

10:30 A.M. BREAK
10:40 A.M. Building Libraries of Adverse Outcome Pathways

Dr. Daniel Villeneuve, Aquatic Toxicologist, Toxic Effects Characterization 

Research Branch, MED, NHEERL, ORD, EPA

12:00 P.M. LUNCH

1:15 P.M. Building Knowledgebases and Decision Support Tools

Dr. Patricia Schmieder, Chief Molecular and Cellular Mechanisms Research 

Branch, MED, NHEERL, ORD, EPA

Partnership with Stakeholders

2:30 P.M. Partnerships with Stakeholders – PPDC Workgroup 

Kristie Sullivan, MPH, Scientific and Policy Advisor of

Physicians Committee for Responsible Medicine

3: 15 P.M. BREAK

Case Studies

3:30 P.M. Introduction to Integration of Toxicogenomic Technology to Inform Risk 

Assessment; A Case Study: Propiconazole

Ms. Nancy McCarroll, Geneticist, RAB VI, Health Effects Division, OPP, EPA

4:05 P.M. Integration of Toxicogenomic Technology to Inform Risk Assessment; A 

Case Study: Propiconazole

Dr. Stephen Nesnow, Senior Research Scientist, Integrated Systems Toxicology

Division, NHEERL, ORD, EPA

5:30 P.M. ADJOURN
Wednesday, May 25, 2011

8:30 A.M. Opening of Meeting and Administrative Procedures

Dr. Fred Jenkins, Designated Federal Official, Office of Science Coordination and 

Policy, EPA

8:35 A.M. Introduction and Identification of Panel Members

Dr. Kenneth Portier, Chair, FIFRA Scientific Advisory Panel

8:45 A.M. Introduction to Use of Adverse Outcome Pathway (AOP) to Inform Risk 

Assessment: Triclosan Case Study

Dr. Timothy F. McMahon, Senior Toxicologist, Antimicrobial Division, OPP, 

EPA

9:15 A.M. Research approach - Mapping the Thryroid AOP for Neurodevelopmental 

Effects: Triclosan Case Study

Dr. Kevin Crofton, Integrated Systems Toxicology Division, NHEERL, ORD, 

EPA

10:15 A.M. Research approach – Experimental Studies: Triclosan Case Study

Dr. Tammy Stoker, Research Biologist, Endocrine Toxicology Branch, Toxicity

Assessment Division, NHEERL, ORD, EPA 

11:15 P.M. BREAK

11:25 P.M. Public Comments

12:00 P.M. LUNCH

1:10 P.M. Public Comments

3:10 P.M. BREAK

3:20 P.M. Presentation of Charge Questions on OPP’s Strategic Vision

Dr. Jennifer McLain, Deputy Director, Antimicrobial Division, OPP, EPA

3:30 P.M. Discussion of Charge Questions

5:30 P.M. ADJOURN
Thursday, May 26, 2011

8:45 A.M. Opening of Meeting and Administrative Procedures

Dr. Fred Jenkins, Designated Federal Official, Office of Science Coordination and 

Policy, EPA

8:50 A.M. Introduction and Identification of Panel Members

Dr. Kenneth Portier, Chair, FIFRA Scientific Advisory Panel

9:00 A.M. Discussion of Charge Questions (Cont’d for OPP’s Strategic Vision)

10:00 A.M. BREAK

10:10 A.M. Presentation of Charge Questions for Case Study I

Dr. Jennifer McLain, Deputy Director, Antimicrobials Division, OPP

10:20 A.M. Discussion of Charge Questions

12:00 A.M. LUNCH

1:15 P.M. Discussion of Charge Questions (Cont’d for Case Study 1)

2:15 P.M. BREAK

2:25 P.M. Presentation of Charge Questions for Case Study II

Dr. Timothy F. McMahon, Senior Toxiciologist, Antimicrobial Division, OPP, 

EPA

2:35 P.M. Discussion of Charge Questions

5:30 P.M. ADOURN

Please be advised that agenda times are approximate; when the discussion for one topic is 

completed, discussions for the next topic will begin. For further information, please contact the 

Designated Federal Official for this meeting, Dr. Fred Jenkins, via telephone: (202) 564-3327; 

fax: (202) 564-8382; or email: jenkins.fred@epa.gov