### 1 Appendix B. Table of Generic Data Requi rements and Studies Used to Make the Reregistration Decision for MGK 264

GUIDE TO APPENDIX B

Appendix B contains a listing of da ta requirements which support the reregistration for active ingredients within the case MGK 264 covered by this RED. In contains generic data requirements that a pply nitrapyrin in all products, including data requirements for which a “typical form ulation” is the test substance.

The data table is organized in the following formats:

1. Data requirement (Column 1). The data requireme nts are listed in the order in which they appear in 40 CFR 158. The reference numbers accompanying each test refer to the test protocols set in the Pesticide Assessment Guidance, which is available from the National Technical Information Service, 5285 Port Royal Road, Springfield, VA 22161. (703) 487-4650.

2. Use Pattern (Column 2). This column indica tes the use patterns for which the data requirements apply. The following le tter designations are used for the given use patterns.

A. Terrestrial food B. Terrestrial feed C. Terrestrial non-food D. Aquatic food E. Aquatic non-food outdoor F. Aquatic non-food industrial G. Aquatic non-food residential H. Greenhouse food I. Greenhouse non-food J. Forestry K. Residential L. Indoor food M. Indoor non-food N. Indoor medical O. Indoor residential

3. Bibliographic Citation (Column 3). If the Agency has acce ptable data in its files, this column lists the identifying number of each st udy. This normally is the Master Record Identification (MRID) number, but may be a “GS” number is no MRID number has been assigned. Refer to the Bibliography appendi x for a complete citation of the study.

### 2 Appendix B. Data Supporting Guideline Requirements for the Reregistration of MGK 264 New Guideline Number Old Guideline Number Description Use Patterns Citations

PRODUCT CHEMISTRY 830.1550 61-1 Product Identity and Composition All 40443701 830.1600 61-2A Description of materials used to produce the product All 40195801

830.1620 61-2B Description of production process Al 40195801 830.1670 61-2B Formation of Impurities All 40359701 830.1700 62-1 Preliminary Analysis All 40306301 830.1750 62-0 Certification of Limits All 40306301 830.1800 62-3 Analytical Method All 40306301 830.6302 63-2 Color All 40528901 830.6303 63-3 Physical State All 40528901 830.6304 63-4 Odor All 40528901 830.6313 63-13 Stability to normal and elevated temperatures, metals, and metal ions All 42082901

830.7000 63-12 pH All 42082901 830.7050 None UV/Visible Absorption All Data Gap 830.7220 63-6 Boiling Point All 42082901 830.7300 63-7 Density All 42082901 830.7550 63-11 Partition coefficient, shake flask method All 42082901; 42622501; 42622502 830.7840 63-8 Solubility All 42082901 830.7950 63-9 Vapor Pressure All 42082901 ENVIRONMENTAL TOXICITY 850.2100 71-1A Avian Acute Oral Toxicity – Quail 41687301 850.2100 71-1A Avian Acute Oral Toxicity – Duck 41526102 850.2200 71-2A Avian Dietary Toxicity – Quail 41687301 850.2200 71-2B Avian Dietary Toxicity – Duck 41687302 850.2300 71-4A Avian Reproduction – Quail Data Gap 850.2300 71-4B Avian Reproduction – Duck Data Gap 850.1075 72-1A Fish Toxicity Bluegill 41819701; 41819702 850.1075 72-1B Fish Toxicity Bluegill – TEP 41819701; 41819702 850.1075 72-1C Freshwater Fish Toxicity Rainbow Trout 41911501; 41819702 850.1075 72-1D Freshwater Fish Toxicity Rainbow Trout – TEP 41911501; 41819702 850.1010 72-2A Freshwater Invertebrate Toxicity 41526102 850.1075 72-3A Estuarine/Marine Toxicity – Fish Data Gap 850.1025 72-3B Estuarine/Marine Toxicity – Mollusk Data Gap 850.1035 72-3C Estuarine/Marine Toxicity – Shrimp Data Gap 850.1300 72-4 Freshwater Invertebrate Toxicity – Chronic 41526102

850.3020 141-1 Honey Bee Acute Contact Data Gap TOXICOLOGY 870.1100 81-1 Acute Oral Toxicity - Rat 41752305 , Data Gap 870.1200 81-2 Acute Dermal Toxicity – Rabbit/Rat 41860601 870.1300 81-3 Acute Inhalation Toxicity – Rat Data Gap

### 3 New Guideline Number Old Guideline Number Description Use Patterns Citations

870.2400 81-4 Primary Eye Irritation - Rabbit 41860602 870.2500 81-5 Primary Skin Irritation 92122005 870.2600 81-6 Dermal Sensitization Data Gap 870.3100 82-1A Subchronic Oral Toxicity: 90-Day Study Rodent 42970601

870.3150 82-1B Subchronic Oral Toxicity: 90-Day Study Non-rodent 42148101

870.3200 82-2 21-Day Dermal – Rabbit/Rat Data Gap 870.3465 Subchronic Inhalation-rats 43309001 870.3465 Subchronic Inhalation-rats 43309001 870.4100 83-1B Chronic Feeding Toxicity – Non-rodent 42148102 870.3700 83-3A Developmental Toxicity – Rat 41660302 870.3700 83-3B Developmental Toxicity – Rabbit 40352301; 45254201 870.3800 83-4 2-Generation Reproduction – Rat 42155701 870.4100 83-1A Chronic Feeding Toxicity Study – Rat 42148102870.4100 83-1B Chronic Feeding Toxicity Study - Nonrodent 42148102

870.4200 83-2B Carcinogenicity Mice 42148102; 42093802 870.4300 83-5 Combined Chronic Toxicity/Carcinogenicity: Rats 43005301

870.5100 84-2 Bacterial Reverse Gene Mutation 40399101 870.5375 84-2B Cytogenetics 40399102 870.5550 84-2 Unscheduled DNA Synthesis in Mammalian Cells in Culture 41703201

870.7485 85-1 General Metabolism 42729701; 42729702; 42720703; 42729704; 42729705; 42729706 870.7600 85-3 Dermal Penetration and Absorption 42976701; 42976702 ENVIRONMENTAL FATE 835.2120 161-1 Hydrolysis 42222601; 42355001 835.2240 161-2 Photolysis 42222602; 42355002

835.2410 161-3 Photodegradation - Water Photodegradation - Soil 42807501 835.4100 162-1 Aerobic Soil Metabolism 43194501 835.4200 162-2 Anaerobic Soil Metabolism 43194502 835.4300 162-4 Aerobic Aquatic Metabolism Data Gap 835.1240 163-1 Leaching/Adsorp tion/Desorption 42622501 850.1730 165-4 Bioaccumu lation in Fish Data Gap OCCUPATION/RESIDENTIAL EXPOSURE 875.1700 Use and Usage Data Data Gap 875.1400 234 Estimation of Inhalation Exposure, Indoor Sites Data Gap

875.2400 133-3 Dermal (Passive Dosimetry) Exposure Data Gap

### 4 New Guideline Number Old Guideline Number Description Use Patterns Citations

RESIDUE CHEMISTRY 860.1500 171-4K Crop Field Trials (commodities) A,B 42008601