| Name of Subsidiary                                 | Jurisdiction of Incorporation or Organization |
|----------------------------------------------------|-----------------------------------------------|
|  Domestic                                |                                          |
| 400 Professional LLC                               | Delaware                                      |
| Cangene bioPharma, Inc.                            | Maryland                                      |
| Cangene Plasma Resources, Inc.                     | Florida                                       |
| Cangene U.S., Inc.                                 | Delaware                                      |
| Emergent Commercial Operations Frederick Inc.      | Maryland                                      |
| Emergent Biodefense Operations Lansing LLC         | Delaware                                      |
| Emergent Europe Inc.                               | Delaware                                      |
| Emergent International Inc.                        | Delaware                                      |
| Emergent Manufacturing Operations Baltimore LLC    | Delaware                                      |
| Emergent Product Development Gaithersburg Inc.     | Delaware                                      |
| Emergent Product Development Seattle, LLC          | Delaware                                      |
| Emergent Protective Products USA Inc.              | Delaware                                      |
|                                               |                                          |
| International                                      |                                          |
| 3579299 Manitoba Ltd.                              | Manitoba                                      |
| Cangene Corporation Inc.                           | Ontario                                       |
| Cangene Europe Limited                             | England                                       |
| CNJ Holdings Inc.                                  | Manitoba                                      |
| Emergent BioSolutions Malaysia SDN. BHD.           | Malaysia                                      |
| Emergent Global Health Foundation Limited          | England                                       |
| Emergent Product Development Germany GmbH          | Germany                                       |
| Emergent Product Development UK Limited            | England                                       |
| Emergent Protective Products Canada ULC            | Canada                                        |
| Emergent Sales and Marketing Australia Pty Limited | Australia                                     |
| Emergent Sales and Marketing Germany GmbH          | Germany                                       |
| Emergent Sales and Marketing Singapore Pte. Ltd.   | Singapore                                     |
| EPIC Bio Pte. Limited                              | Singapore                                     |
| Oxford-Emergent Tuberculosis Consortium Limited    | England                                       |
|                                               |                                          |
|                                               |                                          |