Product Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Print Date: 19 Oct 2012

®(TM)*Trademark

Page 1 of 13 The Dow Chemical Company encourages and expects you to read and understand the entire (M)SDS, as there is important i nformation throughout the document. We expect you to follow the precautions identified in this document unless your use conditions would necessitate other appropriate methods or

actions.



## 1. Product and Company Identification

Product Name SPECFLEX* NE 447 Isocyanate DA

COMPANY IDENTIFICATI ON The Dow Chemical Company

2030 Willard H. Dow Center

Midland

, MI 48674

United States

Customer Information Number: 800

- 258

- 2436



### EMERGENCY TELEPHONE NUMBER

24

- Hour Emergency Contact: 989

- 636

- 4400 Local Emergency Contact: 989

- 636

- 4400



## 2. Hazards Identification

Emergency Overview

Color: Brown Physical State: Liquid.

Odor: Characteristic Hazards of product:

WARNING! Causes eye irritation. Causes skin irritation. Harmful if inhaled. May cause allergic skin reaction. May cause allergic respiratory reaction. Isolate area. Keep upwind of spill. Stay out of low areas. Elevated temperatures can cause hazardous polymerization. Material reacts slowly with water, releasing carbon dioxide which can cause pressu re buildup and rupture of closed containers. Elevated temperatures accelerate this reaction. Toxic fumes may be released in fire situations. Possible cancer hazard. May cause cancer based on animal data.



### OSHA Hazard Communication Standard This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29

CFR 1910.1200. 

# Material Safety Data Sheet

The Dow Chemical CompanyProduct Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 2 of 13 

### Potential Health Effects Eye Contact: May cause severe eye irritation. May cause moderate corneal injury. Vapor may cause eye irritation experienced as mild discomfort and redness.

Skin Contact: Prolonged contact may cause severe skin irritation with local redness and discomfort. May stain skin. Skin Absorption: Prolonged skin contact is unlikely to result in absorption of harmful amounts.

Skin Sensitization: A component in this mixture has been shown to be a skin sensitizer. Animal studies have shown that skin contact with isocyanates may play a role in respiratory sensitization.

Inhalation: Easily attainable vapor concentrations may cause serious adverse effects, even death. Excessive exposure to TDI may cause severe irritation of the upper respiratory tract and lungs, fluid in the lungs, permanent decrease of lung function, neurologic disorders, cholinesterase depression and gastrointestinal dis tress. Effects may be delayed. Decreased lung function has been associated with overexposure to isocyanates. Respiratory Sensitization: A component in this mixture may cause an allergic respiratory response. Reexposure to extr emely low isocyanate concentrations may cause allergic respiratory reactions in individuals already sensitized. Asthma

- like symptoms may include coughing, difficult breathing and a feeling of tightness in the chest. Occasionally, breathing difficulties ma y be life threatening. Ingestion: Low toxicity if swallowed. Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury; however, swallowing larger amounts may cause injury. Swallowing may res ult in gastrointestinal irritation or ulceration. Aspiration hazard: Based on physical properties, not likely to be an aspiration hazard. Effects of Repeated Exposure: Tissue injury in the upper respiratory tract and lungs has been observed in laboratory animals after repeated excessive exposures to MDI/polymeric MDI aerosols.

Cancer Information: An oral study in which high doses of TDI were reported to cause cancer in

animals has b een found to contain numerous deficiencies which compromise the validity of the study. TDI did not cause cancer in laboratory animals exposed by inhalation, the most likely route of

exposure. Lung tumors have been observed in laboratory animals ex posed to respirable aerosol droplets of MDI/Polymeric MDI (6 mg/m3) for their lifetime. Tumors occurred concurrently with respiratory irritation and lung injury. Current exposure guidelines are expected to protect against these effects reported for MDI. Birth Defects/Developmental Effects: Contains component(s) which did not cause birth defects in animals; other fetal effects occurred only at doses toxic to the mother.



### Component CAS # Amount

2,4

- Diisocyanato

- 1

- methylbenzene 584

- 84

- 9 > 60.0

- < 70.0 % Diphenylmethane Diisocyanate, isomers and homologues 9016

- 87

- 9 > 15.0

- < 25.0 %
2,6

- Diisocyanatotoluene 91

- 08

- 7 > 10.0

- < 20.0 % 4,4'

- Methylenediphenyl diisocyanate 101

- 68

- 8 > 5.0

- < 15.0 %



## 4. First

- aid measures

Description of first aid measures

General advice: First Aid responders should pay attention to self

- protection and use the recommended protective clothing (chemical resistant gloves, splash protection). If potential for exposure exists refer to Section 8 for specific personal protective equipment.

Inhalation: Move person to fresh air. If not breathing, give artificial respiration; if by mouth to mouth use rescuer protection (pocket mask, etc) . If breathing is difficult, oxygen should be administered by qualified personnel. Call a physician or transport to a medical facility.

Skin Contact: Remove material from skin immediately by washing with soap and plenty of water.

Remove co ntaminated clothing and shoes while washing. Seek medical attention if irritation persists. Wash clothing before reuse. An MDI skin decontamination study demonstrated that cleaning very soon after exposure is important, and that a polyglycol

- based skin c leanser or corn oil may be more effective than soap and water. This may also apply to other isocyanates. Discard items which cannot 

## 3. Composition InformationProduct Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 3 of 13 be decontaminated, including leather articles such as shoes, belts and watchbands. Suitable emergency safety shower facil ity should be available in work area. Eye Contact: Immediately flush eyes with water; remove contact lenses, if present, after the first 5 minutes, then continue flushing eyes for at least 15 minutes. Obtain medical attention withou t delay, preferably from an ophthalmologist. Suitable emergency eye wash facility should be immediately

available. Ingestion: Do not induce vomiting. Give one cup (8 ounces or 240 ml) of water or milk if available and transport to a medical fac ility. Do not give anything by mouth unless the person is fully conscious.



### Most important symptoms and effects, both acute and delayed
Aside from the information found under Description of first aid measures (above) and Indication of

immediate medical attention and special treatment needed (below), no additional symptoms and effects are anticipated.



### Indication of immediate medical attention and special treatment needed
Maintain adequate ventilation and oxygenation of the patient. Ma y cause respiratory sensitization or

asthma

- like symptoms. Bronchodilators, expectorants and antitussives may be of help. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. Respiratory symptoms, including pulmonary ede ma, may be delayed. Persons receiving significant exposure

should be observed 24

- 48 hours for signs of respiratory distress. Due to irritant properties, swallowing may result in burns/ulceration of mouth, stomach and lower gastrointestinal tract with subs equent stricture. Aspiration of vomitus may cause lung injury. Suggest endotracheal/esophageal control if lavage is done. If you are sensitized to diisocyanates, consult your physician regarding working with other respiratory irritants or sensitizers. Ch olinesterase inhibition has been noted in human exposure but is not of benefit in determining exposure and is not correlated with signs of exposure. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the pati ent. Excessive exposure may aggravate preexisting asthma and other respiratory disorders (e.g. emphysema, bronchitis, reactive airways dysfunction syndrome).



## 5. Fire Fighting Measures

Suitable extinguishing media
Water fog or fine spray. Dry chemical fire extinguishers. Carbon dioxide fire extinguishers. Foam. Alcohol resistant foams (ATC type) are preferred. General purpose synthetic foams (including AFFF) or protein foams may function, but will be less effective. Extinguishing Media to Avoid: Do not use direct water stre am. May spread fire.



### Special hazards arising from the substance or mixture

Hazardous Combustion Products: During a fire, smoke may contain th e original material in addition to combustion products of varying composition which may be toxic and/or irritating. Combustion products may include and are not limited to: Nitrogen oxides. Isocyanates. Hydrogen cyanide.

Carbon monoxide. Carbon dioxide. Unusual Fire and Explosion Hazards: Product reacts with water. Reaction may produce heat and/or

gases. This reaction may be violent

. Container may rupture from gas generation in a fire situation. Violent steam generation or eruption may occur upon application of direct water stream to hot liquids. Dense smoke is produced when product burns.



### Advice for firefighters

Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. Stay upwind. Keep out of low areas where gases (fumes) can accumulate. Water is not recommende d, but may be applied in large quantities as a fine spray when other extinguishing agents are not available. Do not use direct water stream. May spread fire. Fight fire from protected location or safe distance.

Consider the use of unmanned h ose holders or monitor nozzles. Immediately withdraw all personnel from the area in case of rising sound from venting safety device or discoloration of the container. Move container from fire area if this is possible without hazard. Us e water spray to cool fire

- exposed

containers and fire

- affected zone until fire is out. Contain fire water run

- off if possible. Fire water run

-Product Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 4 of 13 off, if not contained, may cause environmental damage. Review the "Accidental Release Measures"

and the "Ecological Information" sections of this (M)SDS. Special Protective Equipment for Firefighters: Wear positive

- pressure self

- con tained breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, boots, and gloves). Avoid contact with this material during fire fighting operations. If contact is likely, change to full chemic al resistant fire fighting clothing with self

- contained breathing apparatus. If this is not available, wear full chemical resistant clothing with self

- contained breathing apparatus and fight fire

from a remote location. For protective equipment in post

- fire or non

- fire clean

- up situations, refer to

the relevant sections.



## 6. Accidental Release Measures

Personal precautions, protective equipment and emergency procedures: Isolate area. Keep unnecessary and unprotected personnel from entering the area. Keep personnel out of low areas. Keep upwind of spill. Ventilate area of leak or spill. See Section 10 for more specific information. Refer to Section 7, Handling, for additional precautionary measures. Use appropriate safety equipment. For additional information, refer to Section 8, Exposure Controls and Personal Protection.

Environmental precautions : Prevent from entering into soil, ditches, sewers, waterways and/or groundwater. See Section 12, Ecological Information.

Methods and materials for containment and cleaning up : Contain spilled material if possible. Collect in suitable and properly labeled containers. Absorb with materials such as: Cat litter. Sand.

Sawdust. See Section 13, Disposal Considerations, for additional information.



## 7. Handling and Storage

Handling
General Handling: Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated contact

with skin. Avoid breathing vapor. Wash thoroughly after handling. Keep container closed. Use with adequate ventilation. Spills of these organic materials on hot fibrous insulations may lead to lowering of the autoignition temperatu res possibly resulting in spontaneous combustion. See Section 8,

EXPOSURE CONTROLS AND PERSONAL PROTECTION.



### Storage Protect from atmospheric moisture. Store in a dry place. Do not store product contaminated with water to prevent potential hazardous reaction. Avoid moisture.

Shelf life: Use within Storage temperature:

6 Months > 15

- < 40 °C



## 8. Exposure Controls / Personal Protection

Exposure Limits
Component List Type Value

| 4,4'

- Methylenediphenyl diisocyanate ACGIH TWA 0.005 ppm

OSHA Table

Z

- 1 Ceiling 0.2 mg/m3 0.02 ppm

| 2,4

- Diisocyanato

- 1

- methylbenzene ACGIH TWA 0.005 ppm SEN

ACGIH STEL 0.02 ppm SEN

OSHA Table

Z

- 1 Ceiling 0.14 mg/m3 0.02 ppmProduct Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 5 of 13 Dow IHG TWA 0.005 ppm R

- SEN, D

- SEN

Dow IHG Ceiling 0.02 ppm R

- SEN, D

- SEN

| 2,6

- Diisocyanatotoluene ACGIH TWA 0.005 ppm SEN

ACGIH STEL 0.02 ppm SEN

Dow IHG TWA 0.005 ppm R

- SEN, D

- SEN

Dow IHG Ceiling 0.02 ppm R

- SEN, D

- SEN

A "SEN" notation following the exposure guideline refers to the potential to produce sensitization, as confirmed by human or animal data.

An R

- SEN notation following the exposure guideline refers to the potential to produce respiratory sensitization, as confirmed by human or animal data.

A D

- SEN notatio n following the exposure guideline refers to the potential to produce dermal sensitization, as confirmed by human or animal data.



### Personal Protection Eye/Face Protection: Use chemical goggles.

Skin Protection: Use protective clothing chemically resistant to this material. Selection of specific items such as face shield, boots, apron, or full body suit will depend on the task.

Hand protection: Use gloves chemically resistant to this material. Examples of preferred glove barrier materials include: Butyl rubber. Chlorinated polyethylene. Polyethylene. Ethyl vinyl alcohol laminate ("EVAL"). Examples of acceptable glove barrier ma terials include: Neoprene. Nitrile/butadiene rubber ("nitrile" or "NBR"). Polyvinyl chloride ("PVC" or "vinyl").

Viton. NOTICE: The selection of a specific glove for a particular application and duration of use in a workplace should also take into acc ount all relevant workplace factors such as, but not limited to: Other chemicals which may be handled, physical requirements (cut/puncture protection, dexterity, thermal protection), potential body reactions to glove materials, as well as

the instructions/ specifications provided by the glove supplier. Respiratory Protection: Atmospheric levels should be maintained below the exposure guideline. When atmospheric levels may exceed the exposure guideline, use an approved air

- purify ing respirator equipped with an organic vapor sorbent and a particle filter. For situations where the atmospheric levels may exceed the level for which an air

- purifying respirator is effective, use a positive

- pressure
air

- supplying respirator (air l ine or self

- contained breathing apparatus). For emergency response or for situations where the atmospheric level is unknown, use an approved positive

- pressure self

contained breathing apparatus or positive

- pressure air line with auxiliary self

- conta ined air supply. The following should be effective types of air

- purifying respirators: Organic vapor cartridge with a particulate pre

- filter. Ingestion: Use good personal hygiene. Do not consume or store food in the work area. Wash hands before smoking or eating.



### Engineering Controls

Ventilation: Use only with adequate ventilation. Local exhaust ventilation may be necessary for some operations. Provide general and/or local exhaust ventilation to control airborne levels below the exposure guidelines. Exhaust systems should be designed to move the air away from the source of vapor/aerosol generat ion and people working at this point. The odor and irritancy of this material are inadequate to warn of excessive exposure.



## 9. Physical and Chemical Properties

Appearance Physical State Liquid.

Color Brown

Odor Characteristic

Odor Threshold No test data available pH No test data available Melting Point No test data available Freezing Point No test data available Boiling Point (760 mmHg) No test data available

. Flash Point

- Closed Cup > 100 °C ( > 212 °F ) ASTM D3278Product Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 6 of 13 Evaporation Rate (Butyl Acetate = 1) No test data available

Flammability (solid, gas) Not applicable to liquids

Flammable Limits In Air Lower : No test data available Upper : No test data available Vapor Pressure No test data available Vapor Density (air = 1) No test data available Specific Gravity (H2O = 1) 1.21 ASTM D1475 Solubility in water (by weight) (reacts with evolution of CO2)

Partition coefficient, n

octanol/water (log Pow) No data available for this p roduct. See Section 12 for individual component data. Autoignition Temperature No test data available Decomposition Temperature > 230 °C ( > 446 °F ) Literature

Kinematic Viscosity No test data available Explosive properties No test data available Oxidizing properties No test data available Volatile Organic Compounds No test data available



## 10. Stability and Reactivity

Reactivity
Diisocyanates react with many materials and the rate of reaction increases with temperature as well as increased contact; these reactions can become violent. Contact is increased by stirring or if the other material mixes with the diisocyanate., Diisocyan ates are not soluble in water and sink to the bottom, but react slowly at the interface. The reaction forms carbon dioxide gas and a layer of solid polyurea., Reaction with water will generate carbon dioxide and heat.



### Chemical stabili ty Stable under recommended storage conditions. See Storage, Section 7.



### Possibility of hazardous reactions

Can occur. Elevated temperatures can cause hazardous polymerization. Polymerization can be catalyzed by: Strong bases. Water.



### Conditions to Avoid: Exposure to elevated temperatures can cause product to decompose. Generation of gas during decomposit ion can cause pressure in closed systems. Pressure build

- up can be rapid. Avoid moisture. Material reacts slowly with water, releasing carbon dioxide which can cause pressure buildup and rupture of closed containers. Elevated temper atures accelerate this

reaction.



### Incompatible Materials: Avoid contact with: Acids. Alcohols. Amines. Water. Ammonia. Bases. Metal compounds. Moist air. Strong oxidizers. Diisocyanates react with many materials and the rate of reaction increases with temperature as well as increased contact; these reactions can become

violent. Contact is incr eased by stirring or if the other material mixes with the diisocyanate. Diisocyanates are not soluble in water and sink to the bottom, but react slowly at the interface. The reaction forms carbon dioxide gas and a layer of solid polyurea. Reaction with water will generate

carbon dioxide and heat. Avoid contact with metals such as: Aluminum. Zinc. Brass. Tin. Copper.

Galvanized metals. Avo id contact with absorbent materials such as: Moist organic absorbents. Avoid unintended contact with polyols. The reaction of polyols and isocyanates generate heat.



### Hazardous decomposition produc ts Decomposition products depend upon temperature, air supply and the presence of other materials. Gases are released during decomposition.Product Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 7 of 13 

## 11

. Toxicological Information

Acute Toxicity
Ingestion As product: Single dose oral LD50 has not been determined.

Dermal As product: The dermal LD50 has not been determined.

Inhalation As product: The LC50 has not been determined. 

### Eye damage/eye irritation
May cause severe eye irritation. May cause moderate corneal injury. Vapor may cause eye irritation experienced as mild discomfort and redness.


### Skin corrosion/irritation
Prolonged contact may cause severe skin irritation with local redness and discomfort. May stain skin.


### Sensitization

Skin A component in this mixture has been shown to be a skin sensitizer. Animal studies have shown that

skin contact wit h isocyanates may play a role in respiratory sensitization. Respiratory A component in this mixture may cause an allergic respiratory response. Reexposure to extremely low isocyanate concentrations may cause allergic respiratory reactions in individuals already sensitized.

Asthma

- like symptoms may include coughing, difficult breathing and a feeling of tightness in the chest. Occasionally, breathi ng difficulties may be life threatening. 

### Repeated Dose Toxicity Tissue injury in the upper respiratory tract and lungs has been observed in laboratory animals after repeated excessive exposures to MDI/polymeric MDI aerosols. 

### Chronic Toxicity and Carcinogenicity
An oral study in which high doses of TDI were reported to cause cancer in animals has been found to

contain numerous de ficiencies which compromise the validity of the study. TDI did not cause cancer in laboratory animals exposed by inhalation, the most likely route of exposure. Lung tumors have been observed in laboratory animals exposed to respirable aerosol droplets of MDI/Polymeric MDI (6 mg/m3) for their lifetime. Tumors occurred concurrently with respiratory irritation and lung injury. Current exposure guidelines are expected to protect against these effects reported for MDI. Carcinogenicity Classifications:

Component List Classification

2,4

- Diisocyanato

- 1

- methylbenzene NTP Anticipated carcinogen.

IARC Possibly carcinogenic to humans. ; 2B 2,6

- Diisocyanatotoluene NTP Anticipated carcinogen.

IARC Possibly carcinogenic to humans. ; 2B 

### Developmental Toxicity Contains component(s) which did not cause birth defects in animals; other fetal effects occurred only

at doses toxic to the mother. 

### Reproductive Toxicity
In animal studies, TDI has been shown not to interfere with reproduction. 

### Genetic Toxicology
Animal genetic toxicity studies on TDI were negative. In vitro studies were inconclusive; in vitro studies were negative in some cases and positive in others. Results of a Drosophila study were reported to be weakly positive; however, these positive findings are believed to be due to degradation of TDI in the solvent delivery vehicle. Genetic toxicity data on MDI are inconclusive. MDI was weakly positive in
some in vitro studies; othe r in vitro studies were negative. Animal mutagenicity studies were predominantly negative.



## 12

. Ecological Information

ToxicityProduct Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 8 of 13 Data for Component: 2,4

- Diisocyanato

- 1

- methylbenzene

M aterial is slightly toxic to aquatic organisms on an acute basis (LC50/EC50 between 10 and 100 mg/L in the most sensitive species tested).

Fish Acute & Prolonged Toxicity

LC50

, Oncorhynchus mykiss (rainbo w trout)

, static test

, 96 h : 133 mg/l Aquatic Invertebrate Acute Toxicity

EC50

, Daphnia magna (Water flea)

, static test

, 48 h : 12.5 mg/l

EC50

, saltwater mysid Mysidopsis bahia

, static test

, 48 h : 18.3 mg/l Aquatic Plant Toxic ity

EC50

, Skeletonema costatum

, static test

, 96 h : 3,230 mg/l

EC50

, Chlorella vulgaris (Fresh water algae)

, static test

, 96 h : 4,300 mg/l Aquatic Invertebrates Chronic Toxicity Value Daphnia magna (Water flea)

, static test

, 21 d

, num ber of offspring

, NOEC: 1.1 mg/l

, LOEC: 2.2 mg/l Data for Component: Diphenylmethane Diisocyanate, isomers and homologues The measured ecotoxicity is that of the hydrolyzed product, generally under conditions maximizing production of soluble species. Material is practically non

- toxic to aquatic organisms on an acute basis (LC50/EC50/EL50/LL50 >100 mg/L in the most sens itive species tested).

Fish Acute & Prolonged Toxicity

Based on information for a similar material: LC50

, Danio rerio (zebra fish)

, static test

, 96 h : > 1,000 mg/l Aquatic Invertebrate Acute Toxicity

Based on information for a similar material: EC50

, Daphnia magna (Water flea)

, static test

, 24

h : > 1,000 mg/l Aquatic Plant Toxicity

Based on information for a similar material: NOEC

, Desmodesmus subspicatus (green algae)

, sta tic test

, Growth rate inhibition

, 72 h : 1,640 mg/l Toxicity to Micro

- organisms

Based on information for a similar material: EC50 ; activated sludge

, static test

, 3 h : > 100 mg/l Toxicity to Soil Dwelling Organisms

EC50

, Eisenia fetida (earthworms)

, 14 d : > 1,000 mg/kg Data for Component: 2,6

- Diisocyanatotoluene Material is slightly toxic to aquatic organisms on an acute basis (LC50/EC50 between 10 and 100 mg/L in t he most sensitive species tested).

Fish Acute & Prolonged Toxicity

LC50

, Oncorhynchus mykiss (rainbow trout)

, static test

, 96 h : 133 mg/l Aquatic Invertebrate Acute Toxicity

EC50

, Daphnia magna (Water flea)

, static test

, 48 h : 12.5 mg/l

EC50

, saltwater mysid Mysidopsis bahia

, static test

, 48 h : 18.3 mg/l Aquatic Plant Toxicity

EC50

, Skeletonema costatum

, static test

, 96 h : 3,230 mg/l

EC50

, Chlorella vulgaris (Fresh water algae)

, static test

, 96 h : 4,300 mg/l Aquatic Invertebrates Chronic Toxicity Value Daphnia magna (Water flea)

, static test

, 21 d

, number of offspring

, NOEC: 1.1 mg/l

, LOEC: 2.2 mg/l Data for Component: 4,4'

- Methylenediphenyl diisocyanate The measured ecotoxicity is that of the hydrolyzed product, generally under conditions maximizing production of soluble species. Material is practically non

- toxic to aquatic organisms on an acute basis (LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).

Fish Acute & Prolonged Toxicity

Based on information for a similar ma terial: LC50

, Danio rerio (zebra fish)

, static test

, 96 h : > 1,000 mg/l Aquatic Invertebrate Acute ToxicityProduct Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 9 of 13 Based on information for a sim ilar material: EC50

, Daphnia magna (Water flea)

, static test

, 24

h : > 1,000 mg/l Aquatic Plant Toxicity

Based on informa tion for a similar material: NOEC

, Desmodesmus subspicatus (green algae)

, static test

, Growth rate inhibition

, 72 h : 1,640 mg/l Toxicity to Micro

- organisms

Based on information for a similar material: EC50 ; activated sludge

, static test

, 3 h : > 100 mg/l Toxicity to Soil Dwelling Organisms

EC50

, Eisenia fetida (earthworms)

, 14 d : > 1,000 mg/kg



### Persistence and Degradability

Data for Component: 2,4

- Diisocyanato

- 1

- methylbenzene In the aquatic and terrestrial environment, material reacts with water forming predominantly insoluble polyureas which appear to be stable. In the atmospheric environment, material is expected to have a short tropospheric half

- life, based on calcul ations and by analogy with related diisocyanates.

Data for Component: Diphenylmethane Diisocyanate, isomers and homologues In the aquatic and terrestrial environment, material reacts with wa ter forming predominantly insoluble polyureas which appear to be stable. In the atmospheric environment, material is expected to have a short tropospheric half

- life, based on calculations and by analogy with related diisocyanates. OECD Biodegradation Tests: Based on information for a similar material: Biodegradation Exposure Time Method 10 Day Window

0 % 28 d OECD 302C Test Not applicable

Data for Component: 2,6

- Diisocyanatotoluene In the aquatic and terrestrial environment, material reacts with water forming predominantly insoluble polyureas which appear to be stable. In the atmospheric environment, material is expected to have a short tropospheric half

- life, based on calculations and by analogy with related diisocyanates.

Data for Component: 4,4'

- Methylenediphenyl diisocyanate In the aquatic and terrestrial environment, material reacts with water forming predominantly insoluble polyureas which appear to be stable. In the atmospheric environment, material is expected to have a short tropospheric h alf

- life, based on calculations and by analogy with related diisocyanates. OECD Biodegradation Tests: Based on information for a similar material: Biodegradation Exposure Tim e Method 10 Day Window

0 % 28 d OECD 302C Test Not applicable



### Bioaccumulative potential

Data for Component: 2,4

- Diisocyanato

- 1

- methylbenzene

Bioaccumulation: In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominantly insoluble polyureas. Data for Component: Diphenylmethane Diisocyanate, isomers and homologues

Bioaccumulation: In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominantly insoluble polyureas. Data for Component: 2,6

- Diisocyanatotoluene

Bioaccumulation: In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominantly insoluble polyureas. Data for Component: 4,4'

- Methylenediphenyl diisocyanate

Bioaccumulation: In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predomina ntly insoluble polyureas.



### Mobility in soilProduct Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 10 of 13 Data for Component: 2,4

- Diisocyanato

- 1

- methylbenzene Mobility in soil: In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominant ly insoluble polyureas. Data for Component: Diphenylmethane Diisocyanate, isomers and homologues Mobility in soil: In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominantly insoluble polyureas. Data for Component: 2,6

- Diisocyanatotoluene Mobility in soil: In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominantly insoluble polyureas. Data for Component: 4,4'

- Me thylenediphenyl diisocyanate Mobility in soil: In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominantly i nsoluble polyureas.



## 13. Disposal Considerations

DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY OF WATER. All disposal practices must be in compliance with all Federal, State/Provincial and local laws and regulations. Regulations may vary in different locations. Waste characterizations and compliance with applicable laws a re the responsibility solely of the waste generator. AS YOUR SUPPLIER, WE HAVE

NO CONTROL OVER THE MANAGEMENT PRACTICES OR MANUFACTURING PROCESSES OF

PARTIES HANDLING OR USING THIS MATERIAL. THE INFORMATION PRESENTED H ERE

PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS INTENDED CONDITION AS DESCRIBED IN MSDS SECTION: Composition Information. FOR UNUSED & UNCONTAMINATED PRODUCT, the preferred options include sending to a licensed, permitted: Incinerator or other

thermal destruction device. Treatment and disposal methods of used packaging: Empty containers should be recycled or otherwise disposed of by an approved waste management facility. Waste characterizations and compliance with applicable laws are the responsibility solely of the waste generator. Do not re

- use containers for any purpose.



## 14. Transport Information

DOT Non

- Bulk Proper Shipping Name: TOLUENE DIISOCYANATE

Hazard Class: 6.1 ID Number: UN2078 Packing Group: PG II



### DOT Bulk Proper Shipping Name: TOLUENE DIISOCYANATE

Hazard Class: 6.1 ID Number: UN2078 Packing Group: PG II



### IMDG Proper Shipping Name: TOLUENE DIISOCYANATE

Hazard Class: 6.1 ID Number: UN2078 Packing Group: PG II

EMS Number: F

- A,S

- A Marine pollutant.: No



### ICAO/IATA Proper Shipping Name: TOLUENE DIISOCYANATE

Hazard Class: 6.1 ID Number: UN2078 Packing Group: PG II Cargo Packing Instruction: 662 Passenger Packing Instruction: 654

Additi onal Information

Reportable quantity: 110 lb

– TOLUENE DIISOCYANATE

, 33,333 lb

– MDIProduct Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 11 of 13 This information is not intended to convey all specific regulatory or operational requirements/information relating to this product. Additional transportation system information can be

obtained thr

ough an authorized sales or customer service representative. It is the responsibility of the transporting organization to follow all applicable laws, regulations and rules relating to the transportation of the material.



## 15. Regulatory Information

OSHA Hazard Communication Standard This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29

CFR 1910.1200. 

### Superfund Amendments and Re authorization Act of 1986 Title III (Emergency Planning and Community Right

- to

- Know Act of 1986) Sections 311 and 312 Immediate (Acute) Health Hazard Yes Delayed (Chronic) Health Hazard Yes

Fire Hazard No

Reactive Hazard Yes

Sudden Release of Pressure Hazard No

Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency Planning and Community Right

- to

- Know Act of 1986) Section 313 This product contains the following substances which are subject to the reporting requirements of Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 and which are

listed in 40 CFR 372. Component CAS # Amount

2,4

- Diisocyanato

- 1

- methylbenzene 584

- 84

- 9 > 60.0

- < 70.0 % Diphenylmethane Diisocyanate, isomers and homologues 9016

- 87

- 9 > 15.0

- < 25.0 %

2,6

- Diisocyanatotoluene 91

- 08

- 7 > 10.0

- < 20.0 % 4,4'

- Methylenediphenyl diisocyanate 101

- 68

- 8 > 5.0

- < 15.0 %

Pennsylvania (Worker and Community Right

- To

- Know Act): Pennsylvania Hazardous Substances List and/or Pennsy lvania Environmental Hazardous Substance List: The following product components are cited in the Pennsylvania Hazardous Substance List and/or the Pennsylvania Environmental Substance List, and are present at levels which require reporting. Component CAS # Amount

2,4

- Diisocyanato

- 1

- methylbenzene 584

- 84

- 9 > 60.0

- < 70.0 % Diphenylmethane Diisocyanate, isomers and homologues 9016

- 87

- 9 > 15.0

- < 25.0 %

2,6

- Diisocyanatotoluene 91

- 08

- 7 > 10.0

- < 20.0 % 4,4'

- Methylenediphenyl diisocyanate 101

- 68

- 8 > 5.0

- < 15.0 %

Pennsylvania (Worker and Community Right

- To

- Know Act): Pennsylvania Special Hazardous

Substances List: The following product components are cited in the Pennsylvania Special Hazardous Substance List, and are present at levels which require rep orting. Component CAS # Amount

2,4

- Diisocyanato

- 1

- methylbenzene 584

- 84

- 9 > 60.0

- < 70.0 %

California Proposition 65 (Safe Drinking Water and Toxic Enforcement Act of 1986) WARNING: This product contains a chemical(s) known to the State of California to cause cancer.

US. Toxic Substances Control Act All components of this product are either on the TSCA Inventory, are exempt from TSCA Inventory Requirements under 40 CFR 720.30, or comply with the PMN Polymer Exemption 40 CFR 723.250.Product Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 12 of 13 US. New Jersey Worker and Community Right

- to

- Know Act (New Jersey Statute Annotated

Section 34:5A

- 5) The following product components are cited in the New Jersey Environmental Hazardous and Workplace Hazardous Substance Lists: Component CAS # Amount

2,4

- Diisocyanato

- 1

- methylbenzene 584

- 84

- 9 > 60.0

- < 70.0 % Diphenylmethane Diisocyanate, isomers and homologues 9016

- 87

- 9 > 15.0

- < 25.0 %

2,6

- Diisocyanatotoluene 91

- 08

- 7 > 10.0

- < 20.0 % 4,4'

- Methylenediphenyl diisocyanate 101

- 68

- 8 > 5.0

- < 15.0 %

US. New Jersey Worker and Community Right

- to

- Know Act (New Jersey Statute Annotate d

Section 34:5A

- 5) The following product components are cited in the New Jersey Special Hazardous Substance List: Component CAS # Amount

2,4

- Diisocyanato

- 1

- methylbenzene 584

- 84

- 9 > 60.0

- < 70.0 %
2,6

- Diisocyanatotoluene 91

- 08

- 7 > 10.0

- < 20.0 %



## 16. Other Information

Hazard Rating System

NFPA Health Fire Reactivity

2 1 2


### Recommended Uses and Restrictions

Identified uses An isocyanate

-- For use in automotive applications.



### Revision

Identification Number: 1038775 / 0000 / Issue Date 10/18/2012 / Version: 2

. 0 Most recent revision(s) are noted by the bold, double bars in left

- hand margin throughout this

document.



### Legend

N/A Not available

W/W Weight/Weight

OEL Occupational Exposure Limit

STEL Short Term Exposure Limit

TWA Time Weighted Average

ACGIH American Conference of Governmental Industrial Hygienists, Inc.

DOW IHG Dow Industrial Hygiene Guideline

WEEL Workplace Environmental Exposure Level
HAZ_DES Hazard Designation

Action Level A value set by OSHA that is lower than the PEL which will trigger the need for

activities such as exposure monitoring and medical surveillance if exceeded.

Th e Dow Chemical Company urges each customer or recipient of this (M)SDS to study it carefully and consult appropriate expertise, as necessary or appropriate, to become aware of and understand the data contained in this (M)SDS and any hazards associated with the product. The info rmation herein is provided in good faith and believed to be accurate as of the effective date shown above. However, no warranty, express or implied, is given. Regulatory requirements are subject to change and may differ

between various loca tions. It is the buyer's/user's responsibility to ensure that his activities comply with all federal, state, provincial or local laws. The information presented here pertains only to the product as shipped. Since conditions for use of the product are not under the control of the manufacturer, it is the buyer's/user's duty to determine the conditions necessary for the safe use of this product. Due to the proliferation of sources for information such as manufacturer

- specific (M)SDSs, we are n ot andProduct Name: SPECFLEX* NE 447 Isocyanate DA Issue Date: 10/18/2012

Page 13 of 13 cannot be responsible for (M)SDSs obtained from any source other than ourselves. If you have obtained an (M)SDS from another source or if you are not sure that the (M)SDS you have is current, please contact us for the most current version.