EPA Registration Number 

66330-324 

Vol. 2 
• 

Material to be added to a Mini-Jacket 

(in the case where an e-Jacket exists) 

Reg. No. 6b3J{) - 32i./-

Send to SIG: check box 0 

This matel'ial is: 

New stamped-accepted label 

n NewCSF 

U Notification 

c: Final Printed Label 

"''/- Other: ?'GAo" . . i=£~, i ,<Le4Zr2I, " , __ (] 7 

Instructions: Attach this notice on top ofthe 

material. It must be clipped all together and 

there should be NO STAPLES in the material. 

Then give the material with this coversheet to 

staff in the Information Services Center (Room 

230). 

Reviewer's Name: =r-(A~ 1J.,.)hd-J?. 

Phone: 7i2:J.3QS-QJ/Z.Division: --.J?J) __ _ 

Current <lS of Wednesday, March 01, 2006 1 
• • 

UNITED STATES ENVIRONMENTAL PROTEC'TION AGENCY 

WASllINGTON, D,C. 20460 

()H'IC~ Or 

rl\iNU,-, il),,_ f'lSI ICJi)'.5 

A>:n T\'lXIC $\ '1ISTASCE$ 

Bill Washburn 

Arysta Lifcscicncc North America Corporation 

15401 Weston Pkwy Ste. 150 

Cary, NC 27513 

Dear Mr. Washburn: 

Subject: Water Solubility Data 

Thidiazuron Technical 

EPA Registration Number 66330-324 

The water solubility data has been reviewed and is acceptable for the corresponding 

requirements of 40CFR§ 158.190. A copy of the Technical Review Branch (TRB) analysis is 

enclosed. If you have any questions, pic<lsC contact Tracy White by phone at (703) 308-0042 or 

via email at whitcJr\lcv(a epil.g()\', 

Enclosure 

Sincerely. 

oanne 1. Miller 

Product Manager (23) 

Herbicide Branch 

Registration Division (7505P) 

2 
• 

• 

Date: July 12, 2006 

SUBJECT: 

FROM: 

TO: 

Thidiazuron T ~chnical ~ 

Debra 

Product 

Rate 

Chemistry 

;[JiLwf; 

Team 

~ 

Technical Review Branch/RD (7505C) 

Joanne Miller I Tracy White RM 23 

Herbicide Branch I RD (7505C) 

DECISION NO: 219225 

DP BARCODE: 329432 

EPA REG. NO.: 51036-402 

PRODUCT', Thidiazuron Technical 

PCC: 120301 

REGISTRANT: Micro*Flow Company LLC 

USE: Herbicide 

INTRODUCTION: 

• 

The registrant has submitted a required study (MRID No. 468252*Oi) for review for the subject product, Thidiazuron 

Technical. Because the sUbject product is a manufacturing-use product. the registrant needed to submit a missing 

water solubility study (reference guideline 830.7840) for the subject product. The technical review branch (TRB) has 

been asked to review the submitted data for acceptability. 

SUMMARY OF FINDINGS, 

1. The registrant has submitted a GLP Compliance Statement (dated 2t/APR/2006 and OifMAYl2oo6) for the 

submitted study. 

2. The water solubility of the subject product, Thidiazuron Technical, averages 0.0082 9 / L at 20~C. 

CONCLUSIONS: 

TRB has reviewed the submitted study and has concluded: 

t. The submitted study corresponding to reference guideline 830.7840 (Water Solubility) satisfied the corresponding 

requirements of 40CFR§158.190, for the water solubility data requirements. 

3 
• 

SARCODE:329432 Reg. No.: 51036-102 PRODUCT: Thidiazuron Technical 

Common Name: Thidiazuron Technical 

Chemical name: IUPAC: 1-phenYJ-3-(1,2,3-thiadiazol-S-yl)urea 

CAS: N-phenyl-N' -1 ,2,3-thiadiazol-S-y1 urea 

CAS No.: 51707-55-2 

PC Code No.: 120301 

Empirical formula: C9 H8 N4 0 S 

Molecular Weight: 220.25 

Structural formula: 

• 

4 
,------;------------- ~~~~~~ 

.. 

• • 

BARCODE:329432 Reg. No.: 51036-492 PRODUCT: ThidjazurQn Technical 

ATTACHMENT II 

REVIEW OF PRODUCT CHEMISTRY, OPPTS 830 SERIES 

Chemical Name (IUPAC, CAS) 

Chemical Number (CAS; PC Code) 

Registration/Symbol No. 

Type of Product (T, MP, EP) 

DP Barcode 

Reviewer 

Branch Chief 

CAS No. 

PC Code: 

% 

~eborah McCall 

Table 2: Ph sica] and Chemical Properties of {Product Name 1 

GLN Requirement MRID Slatus 

830.7840 WatersoJubility: 468252·01 Y 

Rcsultor Deficiency 

0.0082 giL at 20°C 

5 
UNr! STATES ENVIRONMENTAL PROTECTI AGENCY 

WASHINGTON, D.C. 20460 

MICRO-FLO COMPANY LLC 

530 OAK COURT DRIVE 

MEMPHIS, TN 38117-

May 16,2006 

Report of Analysis for Compliance with PR Notice 86¥5 

OFF!CEOF 

PREVENTION, rr:ST!C1DES AND 

TOXIC SUBSTANCES 

Thank you for your submittal of II-MAY -06. OUf statl'has completed a preliminary 

analysis of the material. The results are provided as follows: 

Your submittal was found to be in full compliance with the standards for submission of 

data contained in PR Notice 86-5. A copy of your bibliography is enclosed, annotated with 

Master Record ID's (MRIDs) assigned to each document submitted. Please use these numbers in 

all future references to these documents. Thank you for your cooperation. If you have any 

questions conceming this data submission, please raise them with the cognizant Product 

Manager, to whom the data have been released. 

6 
May 8. 2006 

USEPA Headquarters 

Joanne Miller- #23 

One Potomac Yard 

2777 S, Crystal Drive 

Arlington, VA 22202 

Subject: Thidiazuron Technical 

EPA Reg. No. 51036-402 

Submission of Water Solubility Data 

Ms. Miller: 

As requested in your letter stamped, March 23, 2006, we are submitting the data for the 

water solubility of the proposed manufacturing-use product. 

Please find encldsed three copies of the following study: 

Water Solubility of Thidiazuron Technical, OPPTS Guidelines 830.7840, 9 pages 

Laboratory Project ID: MI-0602 MRID No. ____ 4_6S_2_5_20_1 __ _ 

Should you have any questions in regards to this submission, please do not hesitate to 

contact me at 901-432-5118 or bye-mail atbilLwashburn@microflocompany.com. 

Respectfully, 

Q I Jl \~ 

Bill Washburn 

<-Y.J- G...)c--':) ~ 

Regulatory Affairs Manager 

:>0. BoY 772099 " 1\~er;IVlis_ Tf'-l 3£;117-2099 ., Office: 90 H132· 5000 " Fax: 90i -il32·51OG . 7 

468252-00 
• • Material to be added to a Mini-Jacket 

(in the case where an e-Jacket exists) 

Reg. No. 5'/03(;,-4-02-

Send to SIG: check box 0 

• This material is: 

• 

o New stamped-accepted label 

o NewCSF 

o Notification 

o Final Printed Label 

~ Other: bak /\.Q!y~ rInstructions: Attach this notice on top of the 

material. It must be clipped all together and there 

should be NO STAPLES in the material. Then give 

the material with this coversheet to staff in the 

Information Services Center (Room 230). 

Reviewer's Name: Iffi.~ k.)hit..e 

Phone: 70:> - .::s D 2> -ODliZDivision: --"KwJ2"'--__ 

Date: 3' ,;L3 - 06 

Current as of Wednesday, March 22, 2006 

8 
Bill Washburn 

Micro Flo Company LLC 

P.O. Box 772099 

• • 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C, 20460 

! 3 

OFFICE OF 

PREVENnON, PESTICIDES AND 

TOXIC SUBSTANCES 

• Memphis, TN 38117 

• 

Dear Mr. Washbum: 

Subject: Storage Stability and Corrosion Data 

Thidiazuron Technical 

EPA Registration Number:51036A02 

Application Submission dated January 6, 2003 

The above mentioned study for the Storage Stability and Corrosion Data for Thidiazuron 

Technical is acceptable. You must submit the data for the water solubility (830.7840) of the 

proposed manufacturing-use product. A copy of the Technical Review Branch (TRB) report is 

enclosed. If you have any questions, please contact Tracy White by phone at (703) 308-0042 or 

via email at white,tracv@epa.gov. 

Enclosure 

Sincerely, 

Joanne L Miller 

Product Manager (23) 

Herbicide Branch 

Registration Division (7505C) 

9 
• 

• 

• • 

DATE OUT: 071 JUNE/2004 

SUBJECT: 

FROM: 

TO: 

PRODUCT CHEMISTRY REVIEW OF MP [X J EP [J 

DP BARCODE Fife Symbol No.: 51036~02 

PRODUCT i i 

)" FOIRMUICATI()N [J 

pee: 

Debra Rate 

Product Chemistry Team 

Technical Review Branch/RD (7505C) 

Marcel Howard I Joanne Miller, RM 23 

tnsectidde Branch/RD{7505C) 

INTRODUCTION: 

NON- FEE 

The registrant has submitted product chemistry data for storage stability and corrosion characteristics in 

support of the registration application for the proposed manufacturing-use product. The product chemistry data 

has been submitted under MRfD No. 458328·01. The proposed manufacturing-use product has Thidiazuron 

(Reg. No. 51036-402,98.3%) as its active ingredient. TRB has been asked to evaluate the product chemistry 

data submitted for the proposed manufacturing-use product. 

SUMMARY OF FINDINGS 

1. The end-use product contains Thidiazuron (Reg, No. 51036-402, 98.3%) as its active ingredient with a 

label cfaim of 98.3%, 

2. The data submitted correspondingt0830 Series Subgroup A (product identity, composition, anatysis)were 

alf previously accepted. 

3. The data submitted corresponding to 830 Series Subgroup B (physical-chemical properties) were 

previousty accepted\ except for the solubifity in water (830.7840), storage stabifity (830,6317) and corrosion 

characteristics (830.6320). 

4. The data submitted for the storage stab'lIity (830.6317) requ"lrements were for time zero, three months, 6 

months and 12 months, [MRtD No. 458328-01] 

5. The data submitted in reference to guidetine 830.6320 (corrosion characteristics) were cotlected by visual 

inspection of the packaging in conjunction with the storage stabifity study. 

CONCLUStONS: 

The TR8 has reviewed the product chemistry data submitted for the proposed technical product and has 

concluded that: 

1. The product chemistry data submitted corresponding to 830 Series Subgroup A were previously accepted. 

2. The product chemistry data submitted corresponding 830 Series Subgroup 8 (physical/chemical 

properties) were previously accepted\ except for the water solubility (830.7840) and those pertaining to 

storage stabifity (830.6317) and corrosion characteristics (830.6320). 

10 
• 

• 

• • 

2 

BARCODE No.:298233 File Symbol No.: 51036-402 PRODUCT NAME: Thidiazuron Technica! 

3, The registrant must submit the data for the water solubility (830.7840) of the proposed manufacturing-use 

product. 

4. The data submitted pertaining to storage and stability (830.6317) and corrosion characteristics (830.6320) 

are acceplro!e. [MR!D No. 458328-011 

11 
• • 

3 

BARCODE No.:298233 File Symbol No.: 51036402 PRODUCT NAME: Thidiazuron Technical 

Storage Time Day Zero 3 Months 6 Months 12 Months 

Thidiazuron Purity Average of 5 tests Test 1: 97.0% Test 1: 97.8% Test 1: 98.0% 

98.3% Test 2: 98.7% Test 2: 98.9% Tesl2: 98.4% 

Corrosion Not observed Not observed Not observed Not observed 

Inspection 

• 

• 

12 
• • • , 

.., F ~A. -OM" No • , .,28," 

Uniled SrllltllS § Registration OFF Identifier Number oEPA Environmental Protection Agency Amendment 

Washington, ac 20460 V Other 

Application for Pesticide - Section I 

1, Compllny/Product Number 2. EPA Produet Mltn8gor 3. Propos~ Clas8ification 

51036-UNE J. Miller o None D Rutricted 

4. CompanvlProduet (Neme) IPMI Thldiazuron Technical 23 

5. Name end Address of Applicant ffncludll ZIP Cod.) 6. Expedited Reveiw. In accordance with FfFRA Section 31cH31 

Micro Flo Company LLC (bHi!, my product is similar or identical in composition and labeling 

p,O, Box 772099 to: 

Memphis, TN 38117 EPA Reg. No. 

o Cheek if this is III nsw sddfllSS Product Name 

Section - II 

• Amol'ldment - Explain below. U Finlll printttd leblll. in fepsons" 10 

Agern::y lener deted 

0 Re$ubmi"ion in response to Agoncy letter deted D ~Me Too· App~c.tion. 

0 Notification - Explein balow. 0 Othar· Explain balow. 

Explanation: usa edditional paoa(s) if n"conery. (For section I end Section ILl 

Submission of 12 month slO1<.1g0 stabllitylcorroslon dala. 

Section - III 

1. Met.rlal nn. Product: WillS. Peekeglld In: 

Child·RlI$istant Peckaging Unit Peckaaing WOlter Soluble Packaging 2. Typa of Containor 

.~~:' ~y" ta y" 

V No No t;jM". Plelllic 

Glellu 

II CortificaUon must 

If ~YOlll~ No. Pllr If ·Yes· No. par Paper 

UnitPackllg'mg wgt. fiber drum oontainsr Packogo wgt conteinar V Other fSpec'lfyf btl $ubmitmd 

I 

3. Lecation of N81 COnlent. Information 4. Size(e) Retoil Container S. Locetlon of Lab'" Olreatlone 

Lv' U Container 50 Kg - ~ On label """ 6. Mllnner in Which Label I' Affixlld to Product ~ Uthograph 0 OtMr 

Peper ;.IUed Stene Od 

Section - IV •••• 

• • 

1. Conlact Poinl (Compl.t# ir.m$ dir.cr/y bs/Dw (or id.ntificlJlion of indivklutlll ro bo conrlJcrtnf, if nocllS$IJI)', to praclJSfl thi$ IJPItliclltien.) 

N~. ntlll T.fophona N~. (lncludll Aree Code) 

Morris Gaskins Manager of Registrations 901-432·5000 • •••••• • • • •••• • • 

Certification 6. ()dt6 "'pplicatibll:· .: 

I cllnify that the statemants I have made on thl, fotm and all attachmont, thereto are true, eccurete end complote. -""" •• • • 

I ecknowfedge Ihat any knowlinglly falsa er misleading SUltMnent may be punishabla by fina or impri.01\tMf\t or (Stamp.ar:·· • 

both under applicable lew. • ••••• 

• ••• 

2. Signature /0 r--6 M 3, ntle • • 

•••• 

~_7 

Managor of Registrations • • 

• • • •• •• 

4. Typed Name / 5. Date 

Morris Gaskins 1/06/03 

EPA Form 8570.' fR.v. 3·94) Pra";ous editiens ere obsolete. 'It11Ite • EPA Fie C09Y loriginat) Yo1low, 

b ... --~---------------------' 

-
• 

• 

• • JAN 1 a 2003 

MICRO FLO CO. 

U.S. ENVIRONMENTAL PROTECTION AGENCY 

Office of Pesticide Programs 

P.O. BOX 772099 

MEMPHIS, TN 381172099 

Report of Analysis for Compliance with PR Notice 86-5 

Thank you for your transmittal of 01/07/03. Our staff 

has completed a preliminary analysis of the material. The results are 

provided as follows: 

Your submittal was found to be in full compliance with 

the standards for submission of data contained in PR 

Notice 86-5. A copy of your bibliography is enclosed, 

annotated with Master Record ID's (MRIDs) assigned to 

each document submitted. Please use these numbers in 

all future references to these documents. Thank you for 

your cooperation. If you have any questions concerning 

this data submission, please raise them with the 

cognizant Product Manager, to whom the data have been 

released . 

14 
• 

.... ---.--------~---

FEDERAL EXPRESS 

• 

January 6, 2003 

Document Processing Desk {APPLl 

Ms. Joanne Miller (PM 23) 

Office of Pesticide Programs (7S04C) 

Crystal Mall 2, Room 258 

1921 Jefferson Davis Highway 

Arlington, VA 22202 

RE, THIDIAZURON TECHNICAL 

EPA File Symbol S1036-UNE 

Dear Ms. Miller, 

The enclosed submission 

Corrosion Characteristics 

referenced product. 

is 12 

product 

Month Storage 

chemistry data 

Please call if you have any questions. 

Regards, 

• 

Morris 

/j-----6 Gaskins ~ Manager of Registrations 

901-432-5119 

morris.gaskins@microflocompany.com 

-158318-00 

Stability and 

for the above 

,,".CO " oj,>::;' 100 .. Merf'cn',$, iN 301',7 .. :Ynce:901-432-5000 .. ~~~:< ~C; -L52-SiOO 

15 
• 

• • 

TRANSMITTAL DOCUMENT 

Name and address of submitter: 

MICRO FLO COMPANY LLC 

P.O. BOX 772099 

MEMPHIS, TN 38117 

Company Official: Morris Gaskins 

Telephone: (901) 432-5000 

4It Regulatory action for which this package is submitted: 

Submission of product chemistry data for THIDIAZURON TECHNICAL 

(EPA File Symbol 51036-UNE) 

Transmittal Date: January 6, 2003 

List of items submitted: 

• 

• 

• 

Transmittal page 

Cover letter 

Application form (8570-1) 

Group B Product Chemistry: 12 Month 

Corrosion Characteristics (3 copies) 

Storage Stability & 

16