United States Chemical Safety December 2011 

Environmental Protection and Pollution Prevention 

Agency (7510P) 

 

Methylene Bis(Thiocyanate) 

Summary Document: 

Registration Review: Initial Docket 

December 2011 

 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov 

Methylene Bis(Thiocyanate) 

Summary Document 

Registration Review: Initial Docket 

December 2011 

Case # 2415 

Date: 

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Docket Number: EPA-HQ-OPP-2011-0613 

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TABLE OF CONTENTS 

Methylene Bis(Thiocyanate) Registration Review Team .......................................................... 4

I. Preliminary Work Plan -- Methylene Bis(Thiocyanate) ........................................................ 5

II. Fact Sheet ................................................................................................................................ 13

III. Summary of Anticipated Data Requirements – Methylene Bis(Thiocyanate) ............... 19

IV. Appendix A: Use Patterns – Methylene Bis(Thiocyanate) .............................................. 21

________________________________________ 

Please Note 

This Preliminary Work Plan and Fact Sheet summarize the Environmental Protection Agency's 

current position based on the following documents: 

1. Product Chemistry, Environmental Fate, and Ecological Effects Scoping Document in 

Support of Registration Review of Methylene bis(thiocyanate). November 22, 2011 

2. Methylene Bis Thiocyanate (MBT): Human Health Risk Assessment Scoping Document 

in Support of Registration Review. October 17, 2011 

Additional supporting documents for the Methylene Bis(Thiocyanate) Case may be found in the 

registration review docket EPA-HQ-OPP-2011-0613 located on the internet at

www.regulations.gov. 
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Methylene Bis(Thiocyanate) Registration Review Team

Human Health & Environmental Effects

Nathan Mottl 

Steven Malish 

Jonathan Chen 

Srinivas Gowda 

Najm Shamim 

William Erickson 

Risk Management

Rebecca von dem Hagen 

Lance Wormell 

Office of General Counsel

Philip Ross 
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I. Preliminary Work Plan -- Methylene Bis(Thiocyanate) 

Introduction:

The Food Quality Protection Act (FQPA) of 1996 mandated a registration review program. All 

pesticides distributed or sold in the United States generally must be registered by the U.S. 

Environmental Protection Agency (USEPA, EPA, or the Agency) based on scientific data 

showing that they will not cause unreasonable risks to human health or the environment when 

used as directed on product labeling. The registration review program is intended to make sure 

that, as the ability to assess risk evolves and as policies and practices change, all registered 

pesticides continue to meet the statutory standard of no unreasonable adverse effects to human 

health or the environment. Changes in science, public policy, and pesticide use practices will 

occur over time. Through the registration review program, the Agency periodically reevaluates 

pesticides to make sure that as change occurs, products in the marketplace can be used safely. 

Information on this program is provided at http://www.epa.gov/oppsrrd1/registration_review/. 

The Agency is implementing the registration review program pursuant to Section 3(g) of the 

Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and will review each registered 

pesticide every 15 years to determine whether it continues to meet the FIFRA standard for 

registration. The Agency will consider benefits information and data as required by FIFRA. The 

public phase of registration review begins when the initial docket is opened for each case. The 

docket is the Agency’s opportunity to state what it knows about the pesticide and what additional 

risk analyses and data or information it believes are needed to make a registration review 

decision. After reviewing and responding to comments and data received in the docket during 

this initial comment period, the Agency will develop and commit to a final work plan and 

schedule for the Methylene Bis(Thiocyanate) Case. 

The Methylene Bis(Thiocyanate) Case (Case Number 2415) includes one active ingredient, PC 

Code 068102. The first product containing methylene bis(thiocyanate) (MBT) as an active 

ingredient was registered in the United States in 1949. Currently, there are 40 MBT products 

registered with EPA. Products containing MBT are registered for use as material preservatives 

for incorporation into products such as adhesives, coatings, fuels, metalworking cutting fluids, 

textiles, plastic products, resin emulsions, paints, paper products and various other products. 

Products containing MBT are also registered as microbiocides for use in pulp/paper mills, 

cooling water systems (recirculating), oil field operations, air washer systems, brewery 

pateurizers, hydrotesting, leather processing and industrial water supply systems. MBTcontaining products are also registered for use as wood preservatives. 

No tolerances or exemptions from tolerances have been established for MBT. MBT is cleared as 

an indirect additive in food contact substances for slimicides in paper and paperboards by FDA 

(29 CFR 176.300). Also, FDA has cleared the use of MBT in adhesives under a threshold of 

regulation; MBT can only be used in packaging materials for dry foods at a level not to exceed 

0.01% active ingredient (21 CFR 170.39). 

The Agency completed a Reregistration Eligibility Decision (RED) for methylene 

(bis)thiocyanate in 1997. At the time of the RED, the Agency was unable to make a 

reregistration decision on MBT’s use as a wood preservative, in leather processing liquid and 
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products and in paint due to the lack of data. The Agency has since received the 90-day 

inhalation study (MRID 45366301) and intends to incorporate it in the anticipated risk 

assessments for the registration review of MBT. 

Documents associated with the registration review of methylene bis(thiocyanate) can be viewed 

at www.regulations.gov in docket EPA-HQ-OPP-2011-0613. Below is a summary of the issues 

relevant to this registration review case. 

Anticipated Risk Assessment and Data Needs:

The Agency anticipates the need to conduct a comprehensive ecological risk assessment, 

including an endangered species risk assessment, for all uses of methylene (bis)thiocyanate. The 

Agency also anticipates the need to conduct a human health risk assessment. The Agency 

anticipates needing additional data for use in conducting the registration review for MBT. 

Ecological Risk: 

 A quantitative ecological risk assessment was not performed for MBT at the time of the 

RED because the Agency did not anticipate any exposure of concern to fish, wildlife, 

and/or endangered species based on the registered use patterns and that discharges to the 

environment complied with all Federal disposal laws and NPDES. For registration 

review, the Agency anticipates the need to conduct a comprehensive ecological risk 

assessment for MBT. 

 The Agency has not conducted a risk assessment that supports a complete endangered 

species determination for MBT. The ecological risk assessment planned during 

registration review will allow the Agency to determine whether MBT’s use has 'no effect' 

or 'may affect' federally listed threatened or endangered species (listed species) or their 

designated critical habitats. When an assessment concludes that a pesticide’s use 'may 

affect' a listed species or its designated critical habitat, the Agency will consult with the 

U.S. Fish and Wildlife Service and/or National Marine Fisheries Services (the Services), 

as appropriate. 

 The Agency anticipates the need to require the following additional ecological data for 

use in the registration review of methylene (bis)thiocyanate. 

850.1400 -- Fish early-life stage toxicity test (freshwater) 

850.4400 -- Aquatic plant toxicology test using Lemna spp., Tier I 

850.5400 -- Algal Toxicity Tier I and Tier II 

850.3020 -- Honey bee acute contact toxicity 

850.3030 -- Honey bee toxicity of residues on foliage 

850.1735 -- Whole sediment acute toxicity invertebrates (freshwater)1

850.1740 -- Whole sediment acute toxicity invertebrates (marine)1

Special Study -- Chronic sediment toxicity test (freshwater invertebrate) 1 

 

1

 If the environmental fate data anticipated as being required for this registration review demonstrate that the halflife of the MBT in the sediment is greater than 10 days and if any one of the following conditions are met (1) Kd 

<50, (2) Koc <1000, or (3) Kow <3, then the registrant may request that the Agency waive the sediment studies. 
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 The Agency anticipates the need to require the following additional environmental fate 

data for use in the registration review of methylene (bis)thiocyanate. 

835.2240 -- Photodegradation in water (at pH 5) 

835.1240 -- Adsorption/desorption 

835.4300 -- Aerobic aquatic metabolism 

835.4400 -- Anaerobic aquatic metabolism 

850.6800 -- Modified activated sludge, respiration inhibition test2

835.3110 -- Ready Biodegradability2

835.3220 -- Porous Pot Test2

835.3280 -- Simulation Tests to Assess the Biodegradability of Chemicals Discharged 

to Wastewater2

835.3240 -- Simulation Test – Aerobic Sewage Treatment: A. Activated Sludge Units2

Special Study -- Leachability of wood preservatives used in contact with water 

 For more information, please refer to Product Chemistry, Environmental Fate, and 

Ecological Effects Scoping Document in Support of Registration Review of Methylene 

bis(thiocyanate), located in the docket. 

Human Health Risk: 

 The most recent human health risk assessments for methylene (bis)thiocyanate were 

completed in 1997, in support of the RED. 

 The Agency anticipates the need to require the following additional human health data 

for use in conducting occupational, residential, dietary and aggregate risk assessments for 

the registration review of methylene (bis)thiocyanate. 

875.1200 -- Dermal indoor exposure 

875.1400 -- Inhalation indoor exposure 

875.1600 -- Application exposure data reporting and calculations 

875.2300 -- Indoor surface residue dissipation 

875.2500 -- Inhalation exposure 

875.2800 -- Description of human activity 

875.2900 -- Data reporting and calculations 

875.1700 -- Product use information (handler) 

875.2700 -- Product use information (postapplication) 

 

2

 The results of the Activated Sludge Respiration Inhibition Test (ASRI) that is expected to be required would 

determine which of these three biodegradation tests would be anticipated to be required. If the ASRI test EC50 is 

less than or equal to 20 mg/L, then either the Biodegradation in Activated Sludge Study or Simulation Test – 

Aerobic Sewage Treatment: A. Activated Sludge Units or the Porous Pot Test would be anticipated to be required. 

If the ASRI test EC50 is greater than 20 mg/L, then the applicant would choose to conduct either: (i) Ready 

Biodegradability or (ii) Biodegradation in Activated Sludge or Simulation Test – Aerobic Sewage Treatment: A. 

Activated Sludge Units or the Porous Pot Test. If the antimicrobial passes the ready biodegradability study, then no 

further testing would be expected to be required. If, however, the antimicrobial fails the ready biodegradability 

study, then the Biodegradation in Activated Sludge or Simulation Test – Aerobic Sewage Treatment: A. Activated 

Sludge Units, or the Porous Pot study would be expected to be required. 
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 The Agency anticipates the need to conduct an aggregate risk assessment based on the 

potential for residential, dietary and drinking water exposure. 

 For more information, please refer to Methylene Bis Thiocyanate (MBT): Human Health 

Risk Assessment Scoping Document in Support of Registration Review, located in the 

docket. 

Product Chemistry: 

 The Agency does not anticipate the need to require additional product chemistry data for 

this registration review case at this time. 

 For more information, please refer to Product Chemistry, Environmental Fate, and 

Ecological Effects Scoping Document in Support of Registration Review of Methylene 

bis(thiocyanate), located in the docket. 

Endocrine Disruptor Screening Program

As required by FIFRA and FFDCA, EPA reviews numerous studies to assess potential adverse 

outcomes from exposure to chemicals. Collectively, these studies include acute, subchronic and 

chronic toxicity, including assessments of carcinogenicity, neurotoxicity, developmental, 

reproductive, and general or systemic toxicity. These studies include endpoints which may be 

susceptible to endocrine influence, including effects on endocrine target organ histopathology, 

organ weights, estrus cyclicity, sexual maturation, fertility, pregnancy rates, reproductive loss, 

and sex ratios in offspring. For ecological hazard assessments, EPA evaluates acute tests and 

chronic studies that assess growth, developmental and reproductive effects in different 

taxonomic groups. As part of its 1997 Reregistration Eligibility Decision for MBT, EPA 

reviewed these data and selected the most sensitive endpoints for relevant risk assessment 

scenarios from the existing hazard database. However, as required by FFDCA section 408(p), 

methylene (bis)thiocyanate is subject to the endocrine screening part of the Endocrine Disruptor 

Screening Program (EDSP). 

EPA has developed the EDSP to determine whether certain substances (including pesticide 

active and other ingredients) may have an effect in humans or wildlife similar to an effect 

produced by a “naturally occurring estrogen, or other such endocrine effects as the Administrator 

may designate.” The EDSP employs a two-tiered approach to making the statutorily required 

determinations. Tier 1 consists of a battery of 11 screening assays to identify the potential of a 

chemical substance to interact with the estrogen, androgen, or thyroid (E, A, or T) hormonal 

systems. Chemicals that go through Tier 1 screening and are found to have the potential to 

interact with E, A, or T hormonal systems will proceed to the next stage of the EDSP where EPA 

will determine which, if any, of the Tier 2 tests are necessary based on the available data. Tier 2 

testing is designed to identify any adverse endocrine-related effects caused by the substance, and 

establish a dose-response relationship between the dose and the E, A, or T effect. 

Under FFDCA section 408(p), the Agency must screen all pesticide chemicals. Between October 

2009 and February 2010, EPA issued test orders/data call-ins for the first group of 67 chemicals, 

which contains 58 pesticide active ingredients and 9 inert ingredients. Methylene 
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(bis)thiocyanate is not among the group of 58 pesticide active ingredients on the initial list to be 

screened under the EDSP. Accordingly, as part of registration review, EPA will issue future 

EDSP orders/data call-ins, requiring the submission of EDSP screening assays for methylene 

(bis)thiocyanate. For further information on the status of the EDSP, the policies and procedures, 

the list of 67 chemicals, future lists, the test guidelines and the Tier 1 screening battery, please 

visit our website: http://www.epa.gov/endo/. 

Timeline

EPA has created the following estimated timeline for the completion of the Methylene 

bis(thiocyanate) registration review: 

Anticipated Schedule

Activities Estimated Month/Year

Phase 1: Opening the docket 

Open Public Comment Period for Docket December 2011

Close Public Comment Period for Docket February 2012 

Phase 2: Case Development 

Develop Final Work Plan (FWP) June 2012 

Issue DCI June 2013 

Data Submission June 2015 

Open Public Comment Period for Preliminary Risk Assessments December 2016 

Close Public Comment Period for Preliminary Risk Assessments January 2017 

Phase 3: Registration Review Decision 

Open Public Comment Period for Proposed Reg. Review Decision June 2017 

Close Public Comment Period for Proposed Reg. Review Decision August 2017 

Final Decision and Begin Post-Decision Follow-up 2017 

Total (years) 6 

Guidance for Commenters:

The public is invited to comment on EPA’s Preliminary Work Plan and rationale. The Agency 

will carefully consider all comments as well as any additional information or data provided in a 

timely manner prior to issuing a final work plan for the Methylene bis(thiocyanate) registration 

review case. 

Trade Irritants:

Through the registration review process, the Agency intends to solicit information on trade 

irritants and, to the extent feasible, take steps toward facilitating irritant resolution. Growers and 

other stakeholders are asked to comment on any trade irritant issues resulting from lack of 

Maximum Residue Limits (MRLs) or disparities between U.S. tolerances and MRLs in key 

export markets, providing as much specificity as possible regarding the nature of the concern. 
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Water Quality:

Methylene (bis)thiocyanate is not identified as a cause of impairment for any water bodies listed 

as impaired under section 303(d) of the Clean Water Act, based on information provided at 

http://iaspub.epa.gov/tmdl_waters10/attains_nation_cy.cause_detail_303d?p_cause_group_id=88

5. In addition, no Total Maximum Daily Loads (TMDL) have been developed for methylene 

(bis)thiocyanate, based on information provided at 

http://iaspub.epa.gov/tmdl_waters10/attains_nation.tmdl_pollutant_detail?p_pollutant_group_id

=885&p_pollutant_group_name=PESTICIDES. 

More information on impaired water bodies and TMDLs can be found at 

http://www.epa.gov/owow/tmdl/. The Agency invites submission of water quality data for this 

pesticide. To the extent possible, data should conform to the quality standards in Appendix A of 

the OPP Standard Operating Procedure: Inclusion of Impaired Water Body and Other Water 

Quality Data in OPP’s Registration Review Risk Assessment and Management Process (see: 

http://www.epa.gov/oppsrrd1/registration_review/water_quality_sop.htm), in order to ensure the 

data can be used quantitatively or qualitatively in pesticide risk assessments. 

Environmental Justice:

EPA seeks to achieve environmental justice, the fair treatment and meaningful involvement of all 

people, regardless of race, color, national origin, or income, in the development, implementation, 

and enforcement of environmental laws, regulations, and policies. To help address potential 

environmental justice issues, the Agency seeks information on any groups or segments of the 

population who, as a result of their location, cultural practices, or other factors, may have 

atypical, unusually high exposure to methylene (bis)thiocyanate compared to the general 

population. Please comment if you are aware of any sub-populations that may have atypical, 

unusually high exposure compared to the general population. 

Structure Activity Relationships: 

EPA must rely upon information of appropriate quality and reliability for each decision made by 

the Agency. In the Office of Pesticide Programs (OPP), the evaluation process for a pesticide 

chemical traditionally begins with the applicant’s submission of a set of studies conducted with 

the specific pesticide chemical of interest. The use of the results of such testing (measured data) 

is a logical, scientifically rigorous process that identifies the physical, chemical, and 

environmental fate properties of the pesticide, as well as the dose and endpoints at which an 

adverse effect can occur in various animal species. 

Today, there is significant interest in alternative techniques, i.e., techniques other than data 

generation that could significantly inform the Agency’s decision-making process. Recently, OPP 

has made increasing use of structure activity relationship (SAR) as part of its regulatory 

decision-making process. In the SAR process, a chemical's molecular structure is compared to 

that of other chemicals for which data are available. These structural similarities are then used to 

make predictive judgments about a chemical’s physical, chemical, and biological properties. 

Thus, the chemical’s physical, chemical, and biological properties are a function of (or directly 

related to) the chemical’s molecular structure. Quantitative SAR is referred to as QSAR. To 
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develop a QSAR, a selected set of measured data on a single physical, chemical, or biological 

property is used to derive a model (an equation) to predict the value of that property. 

Since SAR assessments and QSAR modeling are another set of tools that are available to Agency 

scientists, OPP has begun a process shift that envisions shifting from the current study-by-study 

approach to an approach in which the use of predicted data, generated using validated models, is 

considered along with information from open literature and studies specifically generated under 

Part 161 requirements. All relevant information would be considered as part of a weight-of-theevidence evaluation. 

At this time, EPA believes that for certain endpoints, especially physical/chemical and fate 

properties, that SAR and QSAR might be effectively utilized to fulfill these data requirements 

for many antimicrobial pesticide chemicals. When considering biological properties, at this time, 

EPA believes that SAR and QSAR can be most effectively utilized in the evaluation of 

chemicals that exhibit lower toxicity for human health and/or ecotoxicity parameters. This is 

appropriate because the risk assessment for lower toxicity chemicals can be stream-lined, i.e., a 

screening-level assessment procedure rather than multiple tiers of assessments with progressively 

more data requirements. 

If stakeholders believe that submission of predicted data can fulfill one of the data needs for the 

Methylene Bis(Thiocyanate) case, then the Agency invites submission of this information. The 

submitter would be expected to supply a rationale describing the utility of the information and 

provide documentation on the scientific validity of the information. The determination that the 

predicted data fulfills the data requirement would be at the sole discretion of the Agency. Presubmission consultation with the Agency is encouraged. 

Additional Information:

Stakeholders are also specifically asked to provide available information and data that will assist 

the Agency in refining its risk assessments, including any species-specific ecological effects 

determinations. The Agency is interested in receiving the following information: 

1. Confirmation on the following label information: 

a. Sites of application 

b. Formulations 

c. Application methods and equipment 

d. Maximum application rates 

e. Frequency of application, application intervals and maximum number of 

applications 

f. Geographic limitations on use 

2. Use or potential use distribution 

3. Use history 

4. Usage/use information for non-agricultural uses (e.g., materials preservation) 

5. Typical application interval 

6. State or local use restrictions 

7. Ecological incidents (non-target plant damage and avian, fish, reptilian, amphibian 

and mammalian mortalities) not already reported to the Agency 
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8. Monitoring data 

Next Steps:

After the 60-day comment period closes in February 2012, the Agency will review and respond 

to any comments received in a timely manner, and then issue a Final Work Plan for the 

Methylene Bis(Thiocyanate) Case. 
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II. Fact Sheet 

Background Information:

 Active Ingredient: methylene bis(thiocyanate) (MBT) 

 Case number: 2415 

 PC Code: 068102 

 CAS number: 6317-18-6 

 Technical registrants: Buckman Laboratories Inc., ICL-IP America, Inc., Kemira 

Chemicals, Inc., Rhodia UK Limited, Lamirsa Laboratories Miret S.A., Verichem, Inc. 

 First approved for use in a registered product: 1949 

 No tolerances or exemptions from tolerances have been established for MBT. 

 Antimicrobials Division Chemical Review Manager (CRM): Rebecca von dem Hagen, 

vondem-hagen.rebecca@epa.gov

 Antimicrobials Division Product Manager (PM): Marshall Swindell, 

swindell.marshall@epa.gov

 Chemical Structure: 

 

Use & Usage Information:

 MBT-containing products are registered for use as material preservatives for 

incorporation into products such as adhesives, coatings, fuels, metalworking cutting 

fluids, textiles, plastic products, resin emulsions, paints, paper products and various other 

products. Products containing MBT ares also registered as microbiocides for use in 

pulp/paper mills, cooling water systems (recirculating), oil field operations, air washer 

systems, brewery pateurizers, hydrotesting, leather processing and industrial water supply 

systems. MBT-containing products are also registered for use as wood preservatives to 

control wood sapstain and mold on freshly cut hardwood and softwood lumber, logs, 

poles, posts and timbers. 

Recent/Pending Regulatory Actions:

 There are no recent or pending regulatory actions for MBT.

Ecological Risk Assessment Status:

Please refer to Product Chemistry, Environmental Fate, and Ecological Effects Scoping 

Document in Support of Registration Review of Methylene bis(thiocyanate), located in the 

docket, for a detailed discussion of the ecological risk assessments. 

 A qualitative hazard characterization for aquatic organisms exposed to methylene 

bis(thiocyanate) was completed in support of the 1997 RED. 

 MBT is highly toxic to birds on an acute-oral basis but practically nontoxic on a dietary 

basis. MBT is of high to very high acute toxicity to freshwater and estuarine/marine fish 

and of very high toxicity to aquatic invertebrates. 
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 MBT is hydrolytically stable at pH 5, but degrades easily at pHs 7, and 9. The Agency 

does not expect that MBT will bioaccumulate as its Log Kow is around 2. 

 The common degradates of MBT which can be formed through hydrolysis and photolysis 

are thiocyanate, formic acid, and carbon dioxide. Under environmental conditions 

formation of cyanide from the thiocyanate moiety is not known to occur. 

Human Health Risk Assessment Status:

The following are key findings of the recent human health risk assessments for Methylene 

bis(thiocyanate). Please refer to Methylene Bis Thiocyanate (MBT): Human Health Risk 

Assessment Scoping Document in Support of Registration Review, located in the docket, for a 

detailed discussion of the human health risk assessment. 

Hazard Characterization: 

 MBT is of severe acute toxicity via the inhalation route and moderate acute toxicity via 

the dermal and oral routes. It is a moderate to severe dermal irritant and a positive skin 

sensitizer. 

Dietary (Food and Water): 

 A dietary exposure and risk assessment has not been performed for MBT. 

Residential: 

 The most recent residential assessment was performed for the 1997 RED on dermal 

exposure. Inhalation exposure was not assessed for the RED due to lack of data. 

Aggregate: 

 An aggregate assessment has not been conducted on MBT. 

Occupational: 

 The most recent occupational assessment was performed for the 1997 RED on dermal 

exposure. Inhalation exposure was not assessed for the RED due to lack of data. 

 Through the RED the Agency required mitigation measures including limiting 

mixing/loading systems to closed metering systems for liquid product formulations 

applied to cooling water systems that were greater than 4000 gallons and specified the 

following label statement: "Do not apply by open pouring of liquid to cooling water 

systems; a metering pump delivery system is required for this use and application 

method." 

 
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Cumulative: 

 EPA does not have, at this time, available data to determine whether methylene 

(bis)thiocyanate has a common mechanism of toxicity with other substances or how to 

include this pesticide in a cumulative risk assessment. For the purposes of this 

registration review, EPA has assumed that methylene (bis)thiocyanate does not have a 

common mechanism of toxicity with other substances when used as an antimicrobial as 

registered. 

Incidents:

Ecological: 

 No methylene (bis)thiocyanate ecological incidents have been reported in the Agency’s 

Ecological Incident Information System (EIIS). 

Human Health: 

 There are nine MBT-specific incidents that have been reported in the Office of Pesticide 

Program Incident Data System (IDS). Most of the incidents were as a result of 

acute/short term inhalation exposure. Workers reported irritation and burning of the lung 

tissue as well as airway and vocal cord dysfunction. Long-term respiratory irritation has 

been reported in workers working with MBT containing products. There have also been 

skin irritation incidents reported. 

Tolerances and International Harmonization: 

 No tolerances or exemptions from tolerances have been established for MBT. 

Data Call-In Status:

 The first MBT DCI was issued in March l987. A second DCI was issued as part of the 

Phase 4 reregistration in June 1991. The Agency also issued DCIs in June 1993 for 

additional environmental fate data on aquatic exposure and March 1997 for additional 

inhalation toxicity data in support of the RED. A post-RED Product Specific DCI 

(PDCI) was issued in September 1997. There are currently no outstanding DCI data 

requirements for MBT. 

Labels: 

Registered products, including EPA registration numbers are provided in Table 1 below. For 

future reference, during registration review a list of product registration numbers will be included 

in the docket. Product registration labels may be obtained from the Pesticide Product Label 

System (PPLS) website at: http://oaspub.epa.gov/pestlabl/ppls.home. 

Table 1. Registered Products – Methylene (Bis)Thiocyanate 
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Registration 

No. 

Registration 

Name 

Company 

Name 

Formulation 

Type 

% of Active 

Ingredient 

1022-583 NEXGEN 

IBC 

Manufacturing 

Co. 

Emulsifiable 

Concentrate 14.7 

1448-34 MTC-10 Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 10 

1448-80 METHYLENE 

BIS(THIOCYANATE) 

Buckman 

Laboratories Inc. 

Technical 

Chemical 99 

1448-81 BUSAN 1009 Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 10 

1448-102 BUSAN 1071 Buckman 

Laboratories Inc. 

Soluble 

Concentrate 2.5 

1448-147 M-20-1 Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 10 

1448-148 M-20-2 Buckman 

Laboratories Inc. 

Soluble 

Concentrate 10 

1448-171 M-5-1 Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 2.5 

1448-172 M-5-2 Buckman 

Laboratories Inc. 

Soluble 

Concentrate 2.5 

1448-357 MTC-10-SR Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 10 

1448-358 MTC-10-CT Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 10 

1448-359 MTC-10WB-CT Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 10 

1448-360 MTC-10WB-SR Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 10 

1448-375 MECT-F Buckman 

Laboratories Inc. 

Formulation 

Intermediate 10 

1448-376 BUSAN 1071WB Buckman 

Laboratories Inc. 

Wettable 

Powder 2.5 

1448-377 BUSAN 1009 WB Buckman 

Laboratories Inc. 

Ready-to-Use 

Solution 10 

1448-408 BUSAN 1350 Buckman 

Laboratories Inc. 

Wettable 

Powder 8 
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Registration 

No. 

Registration 

Name 

Company 

Name 

Formulation 

Type 

% of Active 

Ingredient 

1448-435 BUSAN 1265WB Buckman 

Laboratories Inc. 

Soluble 

Concentrate/ 

Solid 

10 

1448-438 BUSAN 1223 Buckman 

Laboratories Inc. 

Emulsifiable 

Concentrate 10 

1448-439 BUSAN 1234 Buckman 

Laboratories Inc. 

Soluble 

Concentrate 10 

1706-112 NALCON 7619 Nalco Company Ready-to-Use 

Solution 10 

1706-200 NALCON 10WB Nalco Company Ready-to-Use 

Solution 10 

3876-121 GE BETZ SLIMICIDE C31 GE Betz, Inc. Ready-to-Use 

Solution 5 

8622-42 METHYLENE BIS 

(THIOCYANATE) 

ICL-IP America, 

Inc. 

Technical 

Chemical 99 

9386-4 AMA-10 Kemira 

Chemicals, Inc. 

Ready-to-Use 

Solution 10 

9386-12 THIONATE Kemira 

Chemicals, Inc. 

Technical 

Chemical 99 

9386-26 AMA-10S Kemira 

Chemicals, Inc. 

Ready-to-Use 

Solution 10 

9386-31 AMA-10W Kemira 

Chemicals, Inc. 

Ready-to-Use 

Solution 10 

33677-1 TOLCIDE(R) MBT Rhodia UK 

Limited 

Technical 

Chemical 99 

47091-12 SM-10P INDUSTRIAL 

MICROBIOCIDE 

Aurora Specialty 

Chemistries 

Ready-to-Use 

Solution 10 

56156-1 X-100 NATURAL SEAL 

WOOD PRESERVATIVE 

American 

Building 

Restoration 

Products Inc 

Ready-to-Use 

Solution .5 

62190-30 ANTIBLU MC-30 Arch Wood 

Protection, Inc. 

Emulsifiable 

Concentrate 14.7 

64715-1 VEDEXIL-DM/K 

Lamirsa 

Laboratories 

Miret S.A. 

Technical 

Chemical 98.95 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

18 of 50 

Registration 

No. 

Registration 

Name 

Company 

Name 

Formulation 

Type 

% of Active 

Ingredient 

67869-17 N-948 TECHNICAL Verichem, Inc. Technical 

Chemical 99 

67869-31 N-948 WB Verichem, Inc. 

Soluble 

Concentrate/ 

Solid 

10 

73612-1 SENTRY 

Chemcolour 

Industries (NZ) 

Ltd. 

Soluble 

Concentrate 6.42 

74655-4 SPECTRUM RX-32 Hercules 

Incorporated 

Ready-to-Use 

Solution 7 

74655-6 SPECTRUM RX-38 Hercules 

Incorporated 

Ready-to-Use 

Solution 5 

74655-7 SPECTRUM RX-31 Hercules 

Incorporated 

Ready-to-Use 

Solution 5 

84377-1 BELLICIDE Bell Performance 

Inc 

Flowable 

Concentrate 2.5 

 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

19 of 50 

III. Summary of Anticipated Data Requirements – Methylene Bis(Thiocyanate) 

The table below summarizes anticipated data needs for the Methylene Bis(Thiocyanate) Case in 

Section I of this document (Preliminary Work Plan), Product Chemistry, Environmental Fate, 

and Ecological Effects Scoping Document in Support of Registration Review of Methylene 

bis(thiocyanate), and Methylene Bis Thiocyanate (MBT): Human Health Risk Assessment 

Scoping Document in Support of Registration Review. 

Table 2. Summary of Anticipated Data Requirements – Methylene (Bis)Thiocyanate 

Guideline 

Number Anticipated Data Requirement Test Material 

Estimated 

Timeframe 

(Measured 

in months 

from DCI 

Receipt) 

875.1700 Product use information (handler) TGAI 12 

875.2700 Product use information (postapplication) TGAI 12 

875.2800 Description of human activity TGAI 12 

875.1200 Dermal indoor exposure TGAI 24 

875.1400 Inhalation indoor exposure TGAI 24 

875.1600 Application exposure data reporting and calculations TGAI 24 

875.2900 Data reporting and calculations TGAI 24 

875.2500 Inhalation Exposure TGAI 24 

875.2300 Indoor Surface Residue Dissipation3 TGAI 24 

835.2240 Photodegradation in water (at pH 5) TGAI 12 

835.1240 Adsorption/Desorption Study TGAI 12 

835.4300 Aerobic Aquatic Metabolism Study TGAI 12 

835.4300 Anaerobic Aquatic Metabolism Study TGAI 12 

850.6800 Modified activated sludge, respiration inhibition test 4 TGAI 12 

 

3

 The anticipated DCI will provide that a protocol must be submitted for review and approval by the Agency prior to 

initiating this study. 

4

The results of the Activated Sludge Respiration Inhibition Test (ASRI) that is expected to be required would 

determine which of these three biodegradation tests would be anticipated to be required. If the ASRI test EC50 is 

less than or equal to 20 mg/L, then either the Biodegradation in Activated Sludge Study or Simulation Test – 

Aerobic Sewage Treatment: A. Activated Sludge Units or the Porous Pot Test would be anticipated to be required. 

If the ASRI test EC50 is greater than 20 mg/L, then the applicant would choose to conduct either: (i) Ready 

Biodegradability or (ii) Biodegradation in Activated Sludge or Simulation Test – Aerobic Sewage Treatment: A. 

Activated Sludge Units or the Porous Pot Test. If the antimicrobial passes the ready biodegradability study, then no 

further testing would be expected to be required. If, however, the antimicrobial fails the ready biodegradability 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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835.3110 Ready Biodegradability4 TGAI 12 

835.3220 Porous Pot Test4 TGAI 12 

835.3240 

Simulation Test – Aerobic Sewage Treatment: A. Activated 

Sludge Units4 TGAI 12 

835.3280 

Simulation Tests to Assess the Biodegradability of 

Chemicals Discharged to Wastewater4 TGAI 12 

850.1400 Fish early-life stage toxicity test (freshwater) TGAI 12 

850.4400 Aquatic plant toxicology test using Lemna spp., Tier I TGAI 12 

850.5400 Algal Toxicity Tier I and Tier II TGAI 12 

850.3020 Honey bee acute contact toxicity TGAI 12 

850.3030 Honey bee toxicity of residues on foliage TGAI 12 

850.1735 Whole sediment acute toxicity invertebrates (freshwater)5 TGAI 12 

850.1740 Whole sediment acute toxicity invertebrates (marine)5 TGAI 12 

Special Study Chronic sediment toxicity test (freshwater invertebrate) 5 TGAI 12 

 study, then the Biodegradation in Activated Sludge or Simulation Test – Aerobic Sewage Treatment: A. Activated 

Sludge Units, or the Porous Pot study would be expected to be required. 

5

 If the environmental fate data anticipated as being required for this registration review demonstrate that the halflife of the MBT in the sediment is greater than 10 days and if any one of the following conditions are met (1) Kd 

<50, (2) Koc <1000, or (3) Kow <3, then the registrant may request that the Agency waive the sediment studies. 
IV. Appendix A: Use Patterns – Methylene bis(thiocyanate) 

EPA Reg # 

Formulation 

% A. I. Use Site Treatment Site/Surfaces 

Application Method 

Min App Rate 

Max App Rate 

1022-583 

Emulsifiable Concentrate 14.7 

1448-34 

Ready-toUse Solution 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 0.1 lbs/ton 

0.5-1.5 lbs/ton 

1448-34 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Alum solutions, animal glue solutions, pigment slurries, coating formulations, and starch slurries and solutions Metered 50 ppm 400 ppm 

1448-34 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.7-5.5 lbs/1000 gal water (5-40 ppm) 

3.4-6.8 lbs/1000 gal water (25-50 ppm) 

1448-34 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Retort systems and pasteurizers Metered 

2.0 fl oz/1000 gal water 

4.8-8.0 fl oz/1000 gal water 

1448-34 

Ready-toUse Solution 10.0 

Industrial processes and water systems Drilling Muds and fluids Metered 0.05% 0.28% 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

22 of 50 

1448-34 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

0.2-0.6 fl oz/1000 gal water 

1.3-4.0 fl oz/1000 gal 

1448-34 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

0.6 fl oz/1000 gal 

6.6 fl oz/1000 gal 

1448-34 

Ready-toUse Solution 10.0 Materials Preservative Pigment slurries, adhesives coatings and ink Metered 0.20% 0.5-2.0% 

1448-34 

Ready-toUse Solution 10.0 Materials Preservative 

Solutions, emulsions, adhesives and other aqueous liquid products Incorporation 75 ppm 200 ppm 

1448-34 

Ready-toUse Solution 10.0 

Industrial processes and water systems Air washer Systems Metered 

0.01 gal/1000 gal of fluid 10 ppm 

0.04 gal/1000 gal of fluid 40 ppm 

1448-34 

Ready-toUse Solution 10.0 Materials Preservative Leather, brine cured hides and skins Metered 0.003% (30 ppm) 0.02% (200 ppm) 

1448-34 

Ready-toUse Solution 10.0 Materials Preservative Metalworking Fluids Incorporation 

0.10 gal/1000 gal of fluid 100 ppm 

0.40 gal/1000 gal of fluid 400 ppm 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

23 of 50 

1448-80 

Technical Chemical 99.0 For formulating use only. 

1448-81 

Ready-toUse Solution 10.0 Wood Preservative 

Sapstain and mold on freshly cut hardwood and softwood lumber, logs, poles, posts and timbers Immersion 

5 lbs/100 gal water 

18 lbs/100 gal water 

1448-81 

Ready-toUse Solution 10.0 

Industrial processes and water systems Paper mill systems Metered 

0.1 lbs/ton dry basis 

0.5-1.5 lbs/ton dry basis 

1448-81 

Ready-toUse Solution 10.0 

Industrial processes and water systems Pulp Mills Spray 

0.5 lbs/ton dry basis 

2.0-4.0 lbs/ton dry basis 

1448-81 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Alum solutions, animal glue solutions, pigment slurries, coating formulations, and starch slurries and solutions Metered 50 ppm 400 ppm 

1448-81 

Ready-toUse Solution 10.0 Materials Preservative Particle Board Metered 0.10% 0.30% 

1448-81 

Ready-toUse Solution 10.0 Materials Preservative Bacteriostatic Paper Metered 0.50% 9.00% 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

24 of 50 

1448-81 

Ready-toUse Solution 10.0 Materials Preservative Cooling Tower wood 

Open pour/metering pump 

0.5% 0.6 lbs/1000 ft^2 

0.7% 0.8 lbs/1000ft^2 

1448-81 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.2-0.6 lbs/1000 gal water 

1.2-3.7 lbs/1000 gal water 

1448-81 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.05% 0.25% 

1448-81 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

3.9 fl oz/1000 gal water 

13.0 fl oz/1000 gal water 

1448-81 

Ready-toUse Solution 10.0 Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

0.6 fl oz/1000 gal water 

6.0 fl oz/1000 gal water 

1448-81 

Ready-toUse Solution 10.0 Materials Preservative Leather, brine cured hides and skins Metered 0.003% 30 ppm 0.02% 200 ppm 

1448-81 

Ready-toUse Solution 10.0 Materials Preservative 

Leather, pickled, vegetable, chrome, alternative metal or metal free tanned hides and skins Metered 

0.02% 200 ppm 

0.05-0.25% (500-2500 ppm) 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

25 of 50 

1448-81 

Ready-toUse Solution 10.0 Materials Preservative 

pigment slurries, coatings, caulks, sealants and adhesives Metered 0.5-0.75% 2.5-9.0% 

1448-102 

Soluble Concentrate 02.5 

Wood Preservative 

Sapstain and mold on freshly cut hardwood and softwood lumber, logs, poles, posts and timbers Immersion 

12 lbs/100 gal water 

96 lbs/100 gal water 

1448-102 

Soluble Concentrate 02.5 

Industrial processes and water systems Paper mill systems Metered 

0.4 lbs/ton dry basis 

2.0 lbs/ton dry basis 

1448-102 

Soluble Concentrate 02.5 

Materials Preservative Cooling Tower wood 

Open pour/metering pump 

2.0% 2.4 lbs/1000 ft^2 

2.8% 3.2 lbs/1000ft^2 

1448-102 

Soluble Concentrate 02.5 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.8-2.4 lbs/1000 gal water 

4.8-14.8 lbs/1000 gal water 

1448-102 

Soluble Concentrate 02.5 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.20% 1.00% 

1448-102 

Soluble Concentrate 02.5 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

15.6 fl oz/1000 gal water 

52.0 fl oz/1000 gal water 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

26 of 50 

1448-102 

Soluble Concentrate 02.5 

Materials Preservative Fuel Oil Metered 

1.25 fl oz/100 gal 

2.5 fl oz/100 gal 

1448-102 

Soluble Concentrate 02.5 

Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

2.4 fl oz/1000 gal water 

24.0 fl oz/1000 gal water 

1448-102 

Soluble Concentrate 02.5 

Materials Preservative Leather, Hides and Skins Metered 

1.2 lbs/1000lbs 

8.0 lbs/1000lbs 

1448-102 

Soluble Concentrate 02.5 

Materials Preservative 

Leather, pickled, vegetable, chrome, alternative metal or metal free tanned hides and skins Metered 

2.0 lbs/1000lbs 

10.0 lbs/1000lbs 

1448-102 

Soluble Concentrate 02.5 

Materials Preservative Coatings Metered 2.00% 36.00% 

1448-147 

Ready-toUse Solution 10.0 Materials Preservative Cooling Tower wood 

Open pour/metering pump 

0.5% 0.6 lbs/1000 ft^2 

0.7% 0.8 lbs/1000ft^2 

1448-147 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.2-0.6 lbs/1000 gal water 

1.2-3.7 lbs/1000 gal water 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

27 of 50 

1448-147 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.05% 0.25% 

1448-147 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

3.9 fl oz/1000 gal water 

13.0 fl oz/1000 gal water 

1448-147 

Ready-toUse Solution 10.0 Materials Preservative Fuel Oil Metered 3.0 fl oz/1000 gal 6.0 fl oz/1000 gal 

1448-147 

Ready-toUse Solution 10.0 Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

0.6 fl oz/1000 gal water 

6.0 fl oz/1000 gal water 

1448-148 

Soluble Concentrate 10.0 

Materials Preservative Cooling Tower wood 

Open pour/metering pump 

0.5% 0.6 lbs/1000 ft^2 

0.7% 0.8 lbs/1000ft^2 

1448-148 

Soluble Concentrate 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.2-0.6 lbs/1000 gal water 

1.2-3.7 lbs/1000 gal water 

1448-148 

Soluble Concentrate 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.05% 0.25% 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

28 of 50 

1448-148 

Soluble Concentrate 10.0 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

3.9 fl oz/1000 gal water 

13.0 fl oz/1000 gal water 

1448-148 

Soluble Concentrate 10.0 

Materials Preservative Fuel Oil Metered 

3.0 fl oz/1000 gal 

6.0 fl oz/1000 gal 

1448-148 

Soluble Concentrate 10.0 

Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

0.6 fl oz/1000 gal water 

6.0 fl oz/1000 gal water 

1448-171 

Ready-toUse Solution 02.5 Materials Preservative Cooling Tower wood 

Open pour/metering pump 

2.0% 2.4 lbs/1000 ft^2 

2.8% 3.2 lbs/1000ft^2 

1448-171 

Ready-toUse Solution 02.5 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.8-2.4 lbs/1000 gal water 

4.8-14.8 lbs/1000 gal water 

1448-171 

Ready-toUse Solution 02.5 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.20% 1.00% 

1448-171 

Ready-toUse Solution 02.5 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

15.6 fl oz/1000 gal water 

52.0 fl oz/1000 gal water 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

29 of 50 

1448-171 

Ready-toUse Solution 02.5 Materials Preservative Fuel Oil Metered 1.25 fl oz/1000 gal 2.5 fl oz/1000 gal 

1448-171 

Ready-toUse Solution 02.5 Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

2.4 fl oz/1000 gal water 

24.0 fl oz/1000 gal water 

1448-172 

Soluble Concentrate 02.5 

Materials Preservative Cooling Tower wood 

Open pour/metering pump 

2.0% 2.4 lbs/1000 ft^2 

2.8% 3.2 lbs/1000ft^2 

1448-172 

Soluble Concentrate 02.5 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.8-2.4 lbs/1000 gal water 

4.8-14.8 lbs/1000 gal water 

1448-172 

Soluble Concentrate 02.5 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.20% 1.00% 

1448-172 

Soluble Concentrate 02.5 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

15.6 fl oz/1000 gal water 

52.0 fl oz/1000 gal water 

1448-172 

Soluble Concentrate 02.5 

Materials Preservative Fuel Oil Metered 

1.25 fl oz/1000 gal 

2.5 fl oz/1000 gal 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

30 of 50 

1448-172 

Soluble Concentrate 02.5 

Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

2.4 fl oz/1000 gal water 

24.0 fl oz/1000 gal water 

1448-357 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.05% 0.28% 

1448-357 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

0.2-0.6 fl oz/1000 gal water 

1.3-4.0 fl oz/1000 gal water 

1448-357 

Ready-toUse Solution 10.0 Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

0.6 fl oz/1000 gal water 

6.6 fl oz/1000 gal water 

1448-358 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.7-3.4 lbs/1000 gal water (5-25 ppm) 

5.5-6.8 lbs/1000 gal water (40-50 ppm) 

1448-358 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Retort systems and pasteurizers Metered 

2.0 fl oz/1000 gal water 

4.8-8.0 fl oz/1000 gal water 

1448-359 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.7-3.4 lbs/1000 gal water (5-25 ppm) 

5.5-6.8 lbs/1000 gal water (40-50 ppm) 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

31 of 50 

1448-359 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Retort systems and pasteurizers Metered 

2.0 fl oz/1000 gal water 

4.8-8.0 fl oz/1000 gal water 

1448-360 

Ready-toUse Solution 10.0 Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

0.6 fl oz/1000 gal water 

6.6 fl oz/1000 gal water 

1448-359 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.7-3.4 lbs/1000 gal water (5-25 ppm) 

5.5-6.8 lbs/1000 gal water (40-50 ppm) 

1448-359 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Retort systems and pasteurizers Metered 

2.0 fl oz/1000 gal water 

4.8-8.0 fl oz/1000 gal water 

1448-375 

Formulation Intermediate 10.0 For formulating use only. 

1448-376 

Wettable Powder 02.5 

1448-376 

Wettable Powder 02.5 

Wood Preservative 

Sapstain and mold on freshly cut hardwood and softwood lumber, logs, poles, posts and timbers Immersion 

12 lbs/100 gal water 

96 lbs/100 gal water 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

32 of 50 

1448-376 

Wettable Powder 02.5 

Industrial processes and water systems Paper mill systems Metered 

0.4 lbs/ton dry basis 

2.0 lbs/ton dry basis 

1448-376 

Wettable Powder 02.5 

Materials Preservative Cooling Tower wood 

Open pour/metering pump 

2.0% 2.4 lbs/1000 ft^2 

2.8% 3.2 lbs/1000ft^2 

1448-376 

Wettable Powder 02.5 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.8-2.4 lbs/1000 gal water 

4.8-14.8 lbs/1000 gal water 

1448-376 

Wettable Powder 02.5 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.20% 1.00% 

1448-376 

Wettable Powder 02.5 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

15.6 fl oz/1000 gal water 

52.0 fl oz/1000 gal water 

1448-376 

Wettable Powder 02.5 

Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

2.4 fl oz/1000 gal water 

24.0 fl oz/1000 gal water 

1448-376 

Wettable Powder 02.5 

Materials Preservative Leather, Hides and Skins Metered 

1.2 lbs/1000lbs 

8.0 lbs/1000lbs 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

33 of 50 

1448-376 

Wettable Powder 02.5 

Materials Preservative 

Leather, pickled, vegetable, chrome, alternative metal or metal free tanned hides and skins Metered 

2.0 lbs/1000lbs 

10.0 lbs/1000lbs 

1448-376 

Wettable Powder 02.5 

Materials Preservative Coatings Metered 2.00% 36.00% 

1448-377 

Ready-toUse Solution 10.0 Wood Preservative 

Sapstain and mold on freshly cut hardwood and softwood lumber, logs, poles, posts and timbers Immersion 

5 lbs/100 gal water 

18 lbs/100 gal water 

1448-377 

Ready-toUse Solution 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

0.1 lbs/ton dry basis 50 ppm 

0.5 lbs/ton dry basis 400 ppm 

1448-377 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Alum solutions, animal glue solutions, pigment slurries, coating formulations, and starch slurries and solutions Metered 

6.9 lbs/1000 gal water (82 ppm) 

37 lbs/1000 gal water (444 ppm) 

1448-377 

Ready-toUse Solution 10.0 Materials Preservative Particle Board Metered 0.10% 0.30% 

1448-377 

Ready-toUse Solution 10.0 Materials Preservative Bacteriostatic Paper Metered 0.50% 9.00% 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

34 of 50 

1448-377 

Ready-toUse Solution 10.0 Materials Preservative Cooling Tower wood 

Open pour/metering pump 

0.5% 0.6 lbs/1000 ft^2 

0.7% 0.8 lbs/1000ft^2 

1448-377 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.2-0.6 lbs/1000 gal water 

1.2-3.7 lbs/1000 gal water 

1448-377 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.05% 0.25% 

1448-377 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

3.9 fl oz/1000 gal water 

13.0 fl oz/1000 gal water 

1448-377 

Ready-toUse Solution 10.0 Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

0.6 fl oz/1000 gal water 

6.0 fl oz/1000 gal water 

1448-377 

Ready-toUse Solution 10.0 Materials Preservative Leather, brine cured hides and skins Metered 0.003% 30 ppm 0.02% 200 ppm 

1448-377 

Ready-toUse Solution 10.0 Materials Preservative 

Leather, pickled, vegetable, chrome, alternative metal or metal free tanned hides and skins Metered 

0.02-0.05% 200 ppm 

0.05-0.25% 2500 ppm 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

35 of 50 

1448-408 

Wettable Powder 08.0 

Materials Preservative 

pigment slurries, coatings, caulks, sealants and adhesives Metered 0.5-0.75% 2.5-9.0% 

1448-408 

Wettable Powder 08.0 

Materials Preservative 

Leather, brine cured hides and skins 

Pre-packaged water soluble bags 

8-16 oz/1000 lbs 

40-48 oz/1000 lbs 

1448-408 

Wettable Powder 08.0 

Materials Preservative 

Leather, pickled, vegetable, chrome, alternative metal or metal free tanned hides and skins 

Pre-packaged water soluble bags 

8-16 oz/1000 lbs 

32-48 oz/1000 lbs 

1448-408 

Wettable Powder 08.0 

Industrial processes and water systems 

Automated cooling water systems. 

Pre-packaged water soluble bags 30-60 ppm 120-240 ppm 

1448-408 

Wettable Powder 08.0 

Industrial processes and water systems Cooling water systems. 

Pre-packaged water soluble bags 

One lb bag: 16 oz/2000-4000 gal water 4 oz bag: 4 oz/500-1000 gal of water 

One lb bag: 32-64 oz/2000-4000 gal water 4 oz bag: 8-16 oz/500-1000 gal of water 

1448-408 

Wettable Powder 08.0 

Industrial processes and water systems 

Petroleum secondary oil recovery 

Pre-packaged water soluble bags 

4-16 oz/1000 gal 

16-64 oz/1000 gal 

1448-408 

Wettable Powder 08.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids 

Pre-packaged water soluble bags 

64 oz/1000 gal 

384 oz/1000 gal 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

36 of 50 

1448-408 

Wettable Powder 08.0 

Wood Preservative 

Sapstain and mold on freshly cut hardwood and softwood lumber, logs, poles, posts and timbers 

Pre-packaged water soluble bags, spray, dip 

96 oz/100 gal 

384 oz/100 gal 

1448-435 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Air washer Systems Metered 

0.12 lbs/1000 gal water (1.4 ppm) 

0.90 lbs/1000 gal of water (10.8 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. Metered 

0.30-0.40 lbs/1000 gal water (3.6-4.6 ppm) 

0.90-1.86 lbs/1000 gal water (11-22 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

0.14 lbs/ton dry basis 7 ppm 

0.36 lbs/ton dry basis 18 ppm 

1448-435 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Paper additives Metered 

6.9 lbs/1000 gal water (82 ppm) 

37 lbs/1000 gal water (444 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Brewery Pasteurizers Metered 

0.092-0.19 lbs/1000 gal water (1.1-2.3 ppm) 

0.37-0.84 lbs/1000 gal water (4.4-10 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 

0.2 gal/100 barrels (4.1 ppm) 

4.0 gal/100 barrels (83 ppm) 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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1448-435 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Hydrotesting Metered 

0.1 gal/1000 gal of water (11 ppm) 

40 gal/1000 gal of water (4400 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Adheisves and emulsions Metered 

6.9 lbs/1000 gal water(82 ppm) 

37 lbs/1000 gal water(444 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Construction Products Metered 

6.9 lbs/1000 gal water (82 ppm) 

37 lbs/1000 gal water (444 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Materials Preservative 

Crude oil, diesel fuel, residual fuel oils, coal slurries, liquified petroleum gases and pertochemical feedstocks Metered 

32 fl oz/10000 gal fluid (2.5 ppm) 

64-128 fl oz/10000 gal fluid (5.0-10.0 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Materials Preservative 

Leather, pickled, vegetable, chrome, alternative metal or metal free tanned hides and skins Metered 0.025% 0.25% 

1448-435 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Metalworking Fluids Metered 

6.9 lbs/1000 gal water (82 ppm) 

37 lbs/1000 gal water (444 ppm) 

1448-435 

Soluble Concentrate/ Solid 10.0 

Materials Preservative 

Paints, coatings and stains. Pigments, dyes and filler suspensions. Polymer dispersions and emulsions. Metered 

6.9 lbs/1000 gal water (82 ppm) 

69 lbs/1000 gal water (827 ppm) 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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1448-435 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Textiles Metered 

6.9 lbs/1000 gal water (82 ppm) 

69 lbs/1000 gal water (827 ppm) 

1448-438 

Emulsifiable Concentrate 10.0 

Wood Preservative 

Sapstain and mold on freshly cut hardwood and softwood lumber, logs, poles, posts and timbers Immersion 

0.50 gal/1000 gal of fluid 

2.0 gal/1000 gal of fluid 

1448-439 

Soluble Concentrate 10.0 

Wood Preservative 

Sapstain and mold on freshly cut hardwood and softwood lumber, logs, poles, posts and timbers Immersion 

0.50 gal/1000 gal of fluid 

2.0 gal/1000 gal of fluid 

1448-439 

Soluble Concentrate 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 0.1 lbs/ton 

0.5-1.5 lbs/ton 

1448-439 

Soluble Concentrate 10.0 

Materials Preservative 

Alum solutions, animal glue solutions, pigment slurries, coating formulations, and starch slurries and solutions Metered 50 ppm 400 ppm 

1448-439 

Soluble Concentrate 10.0 

Materials Preservative Pulp Mills 

Metered spray 

0.5 lbs/ton dry pulp 

1.5-4.0 lbs/ton dry pulp 

1448-439 

Soluble Concentrate 10.0 

Materials Preservative Particle Board Metered 0.10% 0.30% 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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1448-439 

Soluble Concentrate 10.0 

Materials Preservative Bacteriostatic Paper Metered 0.50% 0.90% 

1448-439 

Soluble Concentrate 10.0 

Industrial processes and water systems Cooling Tower wood 

Open pour/metering pump 

0.5%0.6 lbs/1000 ft^2 

0.7%0.8 lbs/1000ft^2 

1448-439 

Soluble Concentrate 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.2-0.6 lbs/1000 gal water 

1.2-3.7 lbs/1000 gal water 

1448-439 

Soluble Concentrate 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 0.05% 0.25% 

1448-439 

Soluble Concentrate 10.0 

Industrial processes and water systems 

Petroleum secondary oil recovery Metered 

3.9 fl oz/1000 gal water 

13.0 fl oz/1000 gal water 

1448-439 

Soluble Concentrate 10.0 

Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. Metered 

0.6 fl oz/1000 gal water 

6.0 fl oz/1000 gal water 

1448-439 

Soluble Concentrate 10.0 

Materials Preservative 

Pigment slurries, coatings, wood stains, caulks, sealants and adhesives Metered 0.50% 0.75%-9.0% 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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1448-439 

Soluble Concentrate 10.0 

Materials Preservative 

Leather, brine cured hides and skins Metered 

0.003% (30 ppm) 

0.02% (200 ppm) 

1448-439 

Soluble Concentrate 10.0 

Materials Preservative 

Leather, pickled, vegetable, chrome, alternative metal or metal free tanned hides and skins Metered 

0.02-0.05% (200-500 ppm) 

0.075-0.25% (750-2500 ppm) 

1706-112 

Ready-toUse Solution 10.0 Materials Preservative Fuel Oil Storage Tanks Metered 25 ppm 50-100 ppm 

1706-112 

Ready-toUse Solution 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 0.05 lbs/ton 

0.05-1.0 lbs/ton 

1706-112 

Ready-toUse Solution 10.0 Materials Preservative Aqueous solutions and other liquid products Incorporation 75 ppm 750 ppm 

1706-200 

Ready-toUse Solution 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

1.09 fl oz/1000 gal water 

10.9 fl oz/1000 gal water 

1706-200 

Ready-toUse Solution 10.0 Materials Preservative Adheisves and emulsions Incorporation 0.2 lbs/1000 lbs 2.0 lbs /1000 lbs 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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1706-200 

Ready-toUse Solution 10.0 Materials Preservative 

Mineral slurries such as kaolin, calcium carbonate, titanium dioxide and other aqueous dispersions Incorporation 0.002% 0.02% 

1706-200 

Ready-toUse Solution 10.0 Materials Preservative Aqueous solutions and other liquid products Incorporation 75 ppm 750 ppm 

3876-121 

Ready-toUse Solution 05.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. Metered 

12-24 ppm 0.1-0.2 lbs/1000 gal water 

90-120 ppm 0.75-1.0 lbs/1000 gal water 

3876-121 

Ready-toUse Solution 05.0 

Industrial processes and water systems Air washer Systems Metered 

12-24 ppm 0.1-0.2 lbs/1000 gal water 

90-120 ppm 0.75-1.0 lbs/1000 gal water 

8622-42 

Technical Chemical 99.0 

FOR USE BY MANUFACTURERS ONLY IN FORMULATING MICROBIOCIDES FOR USE IN INDUSTRIAL COOLING WATER SYSTEMS AND PAPER MILLS. 

9386-4 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. Metered 

1.6-5.8 fl oz/1000 gal (1.25-4.5 ppm) 

7.9-12.5 fl oz/1000 gal (6.2-9.8 ppm) 

9386-4 

Ready-toUse Solution 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

2.-3.5 fl oz/ton (dry basis) 

4.0-5.0 fl oz/ton (dry basis) 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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9386-4 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids 

Metered/open pour 

1.75 lbs/barrel 5000 PPM 

9386-4 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Oil-field water, and other oil-field Water systems 

Metered/open pour 

0.50 gal/1000 gal of fluid 500 ppm 

0.75 gal/1000 gal of fluid 750 ppm 

9386-4 

Ready-toUse Solution 10.0 Materials Preservative Leather, Hides and Skins Metered 0.25 lbs/1000lbs 2.5 lbs/1000lbs 

9386-12 

Technical Chemical 99.0 

For formulating and compounding products for use in papermill systems, cooling water systems, secondary oil recovery and as a preservative of solutions, emulsions and other non-food liquid products. 

9386-26 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. Metered 

1.6-5.8 fl oz/1000 gal (1.25-4.5 ppm) 

7.9-12.5 fl oz/1000 gal (6.2-9.8 ppm) 

9386-26 

Ready-toUse Solution 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

2.-3.5 fl oz/ton (dry basis) 

4.0-5.0 fl oz/ton (dry basis) 

9386-26 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 

1.75 lbs/barrel 5000 PPM 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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9386-26 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Oil-field water, and other oil-field Water systems Metered 

0.50 gal/1000 gal of fluid 500 ppm 

0.75 gal/1000 gal of fluid 750 ppm 

9386-26 

Ready-toUse Solution 10.0 Materials Preservative 

Solutions, emulsions, adhesives and other aqueous liquid products Incorporation 75 ppm 750 ppm 

9386-26 

Ready-toUse Solution 10.0 Materials Preservative Metalworking Fluids Incorporation 

0.10 gal/1000 gal of fluid 100 ppm 

0.40 gal/1000 gal of fluid 400 ppm 

9386-26 

Ready-toUse Solution 10.0 Materials Preservative 

Crude oil, diesel fuel, residual fuel oils, coal slurries, liquified petroleum gases and pertochemical feedstocks Metered 25 ppm 50-100 ppm 

9386-31 

Ready-toUse Solution 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. Metered 

1.6-5.8 fl oz/1000 gal (1.25-4.5 ppm) 

7.9-12.5 fl oz/1000 gal (6.2-9.8 ppm) 

9386-31 

Ready-toUse Solution 10.0 

Industrial processes and water systems Air washer Systems Metered 

0.01 gal/1000 gal of fluid 10 ppm 

0.04 gal/1000 gal of fluid 40 ppm 

9386-31 

Ready-toUse Solution 10.0 

Industrial processes and water systems Brewery Pasteurizers Metered 

0.01-0.02 gal/1000 gal of fluid 10-20 ppm 

0.03-0.04 gal/1000 gal of fluid 30-40 ppm 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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9386-31 

Ready-toUse Solution 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

2.-3.5 fl oz/ton (dry basis) 

4.0-5.0 fl oz/ton (dry basis) 

9386-31 

Ready-toUse Solution 10.0 Materials Preservative 

Solutions, emulsions, adhesives and other aqueous liquid products Incorporation 75 ppm 750 ppm 

9386-31 

Ready-toUse Solution 10.0 Materials Preservative Metalworking Fluids Incorporation 

0.10 gal/1000 gal of fluid 100 ppm 

0.40 gal/1000 gal of fluid 400 ppm 

9386-31 

Ready-toUse Solution 10.0 Materials Preservative 

Crude oil, diesel fuel, residual fuel oils, coal slurries, liquified petroleum gases and pertochemical feedstocks Incorporation 25 ppm 50-100 ppm 

33677-1 

Technical Chemical 99.0 

For formulation of industrial microbicides and preservatives. 

47091-12 

Ready-toUse Solution 10.0 Materials Preservative Metalworking Fluids Metered 

0.1 gal/1000 gal of fluid 100 ppm 

0.4 gal/1000 gal of fluid 400 ppm 

47091-12 

Ready-toUse Solution 10.0 

Industrial processes and water systems Brewery Pasteurizers Metered 

2-4 oz/1000 gal of water 

6 oz/1000 gal of water 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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47091-12 

Ready-toUse Solution 10.0 

Industrial processes and water systems Air washer Systems Metered 

0.01 gal/1000 gal of fluid 10 ppm 

0.04 gal/1000 gal of fluid 40 ppm 

56156-1 

Ready-toUse Solution 00.5 Wood Preservative 

Seasoned and Unseasoned Wood, sapstain and remedial Brush/spray 

75-100 ft^2/gal24 hrs dry time between coats 

150-200 ft^2/galApply as much as the wood will absorb 

62190-30 

Emulsifiable Concentrate 14.7 

Wood Preservative 

Unseasoned wood sapstain control Dip/Spray 

1/2 gal/100 gal water (dip) 1/4 gal/100 gal water (spray) 

2 gal/100 gal water (dip) 1 gal/20 gal water (spray) 

64715-1 

Technical Chemical 99.0 

For use by manufacturers only in formulating industrial microbiocides and preservatives. 

67869-17 

Technical Chemical 99.0 

Only for formulation into an end use product for use in industrial process and water systems and materials preservatives 

67869-31 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Air washer Systems Metered 

0.12 lbs/1000 gal water (1.4 ppm) 

0.90 lbs/1000 gal of water (10.8 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. Metered 

0.30-0.40 lbs/1000 gal water (3.6-4.6 ppm) 

0.90-1.86 lbs/1000 gal water (11-22 ppm) 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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67869-31 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

0.14 lbs/ton dry basis 7 ppm 

0.36 lbs/ton dry basis 18 ppm 

67869-31 

Soluble Concentrate/ Solid 10.0 

Materials Preservative 

Pulp, pigment slurries, alum, emulsions, adhesives, deloarners, polymers and paper products. Metered 

6.9 lbs/1000 gal water (82 ppm) 

69 lbs/1000 gal water (827 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Brewery Pasteurizers Metered 

0.30-0.40 lbs/1000 gal water (3.6-4.6 ppm) 

0.90-1.86 lbs/1000 gal water (11-22 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems 

Drilling Muds and workover or completeion fluids Metered 

0.2 gal/100 barrels (4.1 ppm) 

4.0 gal/100 barrels (83 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Industrial processes and water systems Hydrotesting Metered 

0.1 gal/1000 gal of water (11 ppm) 

40 gal/1000 gal of water (4400 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Adheisves and emulsions Metered 

6.9 lbs/1000 gal water (82 ppm) 

69 lbs/1000 gal water (827 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Construction Products Metered 

6.9 lbs/1000 gal water (82 ppm) 

69 lbs/1000 gal water (827 ppm) 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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67869-31 

Soluble Concentrate/ Solid 10.0 

Materials Preservative 

Crude oil, diesel fuel, residual fuel oils, coal slurries, liquified petroleum gases and pertochemical feedstocks Metered 

32 fl oz/10000 gal fluid (2.5 ppm) 

64-128 fl oz/10000 gal fluid (5.0-10.0 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Leather, Hides and Skins Metered 0.025% 0.25% 

67869-31 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Metalworking Fluids Metered 

6.9 lbs/1000 gal water (82 ppm) 

37 lbs/1000 gal water (444 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Materials Preservative 

Paints, coatings and stains. Pigments, dyes and filler suspensions. Polymer dispersions and emulsions. Metered 

6.9 lbs/1000 gal water (82 ppm) 

69 lbs/1000 gal water (827 ppm) 

67869-31 

Soluble Concentrate/ Solid 10.0 

Materials Preservative Textiles Metered 

6.9 lbs/1000 gal water (82 ppm) 

69 lbs/1000 gal water (827 ppm) 

73612-1 

Soluble Concentrate 06.4 

Wood Preservative 

Unseasoned wood sapstain control Spray 

40 L/1000 L water 

180 L/1000 L water 

74655-4 

Ready-toUse Solution 07.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

12 ppm 0.1 lbs/1000 gal water 

90-120 ppm 0.75-1.0 lbs/1000 gal water 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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74655-4 

Ready-toUse Solution 07.0 Materials Preservative 

Pulp, pigment slurries, alum, emulsions, adhesives, deloarners, polymers and paper products. Metered 

200-250 ppm 

800-1000 ppm 

74655-6 

Ready-toUse Solution 05.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

12-24 ppm 0.1-0.2 lbs/1000 gal water 

36-120 ppm 0.3-1.0 lbs/1000 gal water 

74655-6 

Ready-toUse Solution 05.0 Materials Preservative 

Pulp, pigment slurries, alum, emulsions, adhesives, deloarners, polymers and paper products. Metered 

200-250 ppm 

800-1000 ppm 

74655-7 

Ready-toUse Solution 05.0 

Industrial processes and water systems Pulp and paper mill systems Metered 

12-60 ppm 0.1-0.5 lbs/1000 gal water 

180-480 ppm1.5-4.0 lbs/1000 gal water 

74655-7 

Ready-toUse Solution 05.0 Materials Preservative Paper and Paperboard Metered 5.0 lb/ton 200 ppm 20.0 lbs /ton 1000 ppm 

74655-7 

Ready-toUse Solution 05.0 Materials Preservative 

Pulp, pigment slurries, alum, emulsions, adhesives, deloarners, polymers and paper products. Metered 

200-250 ppm 

800-1000 ppm 

81910-4 

Emulsifiable Concentrate 10.0 

Industrial processes and water systems 

Industrial recirculating cooling water systems. Metered 

0.2-0.6 fl oz/1000 gal water 

1.2-3.7 fl oz/1000 gal water 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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81910-4 

Emulsifiable Concentrate 10.0 

Industrial processes and water systems Drilling Muds and fluids Metered 

10.0 fl oz/ton 70.0 fl oz/ton 

81910-4 

Emulsifiable Concentrate 10.0 

Industrial processes and water systems 

Oil-field water, and other oil-field Water systems Metered 

4.0fl oz/1000 gal water 

13.0 fl oz/1000 gal water 

81910-4 

Emulsifiable Concentrate 10.0 

Materials Preservative Leather, Hides and Skins Metered 5.0 fl oz/ton 

200.0 fl oz/ton 

81910-4 

Emulsifiable Concentrate 10.0 

Materials Preservative 

Leather, Hides and Skins, Brine cured ONLY Metered 30 ppm 200 ppm 

81910-4 

Emulsifiable Concentrate 10.0 

Industrial processes and water systems Pulp and paper mills Metered 0.05 lb/ton 2.0 lbs /ton 

81910-4 

Emulsifiable Concentrate 10.0 

Materials Preservative Particle Board Incorporation 0.10% 1.00% 

81910-4 

Emulsifiable Concentrate 10.0 

Materials Preservative 

Pigment slurries, coatings, wood stains, caulks, sealants and adhesives Metered 3/4 gal/ton 10 gal/ton 
Docket Number: EPA-HQ-OPP-2011-0613 

www.regulations.gov

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84377-1 

Flowable Concentrate 02.5 

Industrial processes and water systems Cooling Tower wood 

Open pour/metering pump 

2.4 lbs/1000 ft^2 

3.2lbs/1000ft^2 

84377-1 

Flowable Concentrate 02.5 

Industrial processes and water systems 

Industrial recirculating cooling water systems. 

Open pour/metering pump 

0.8-2.4 fl oz/1000 gal water 

4.8-14.8 fl oz/1000 gal water 

84377-1 

Flowable Concentrate 02.5 

Industrial processes and water systems Drilling Muds 

Open pour/metering pump 0.20% 1.00% 

84377-1 

Flowable Concentrate 02.5 

Industrial processes and water systems 

Oil-field water, polymer, or micellar floods, waterdisposal systems, and other oil-field Water systems Metered 

15.6 fl oz/1000 gal water 

52.0 fl oz/1000 gal 

84377-1 

Flowable Concentrate 02.5 

Materials Preservative 

Crude and refined oils such as olefinic, aromatic, paraffinic and naphthenic oils. 

Open pour/metering pump 

2.4 fl oz/1000 gal 

24.0 fl oz/1000 gal 

84377-1 

Flowable Concentrate 02.5 

Materials Preservative Fuel Oil Metered 

0.25-0.5 fl oz/100 gal 

1.25-2.5 fl oz/100 gal