#### § 558.205 Diclazuril.

(a) *Specifications.* Type A medicated article containing 0.2 percent diclazuril.

(b) *Sponsor.* See No. 058198 in [§ 510.600(c) of this chapter](/on/2024-09-23/title-21/section-510.600#p-510.600(c)).

(c) *Related tolerances.* See [§ 556.185 of this chapter](/on/2024-09-23/title-21/section-556.185).

(d) *Conditions of use* —

(1) *Chickens.* For chickens it is used as follows:

| Diclazuril grams/ton | Combination grams/ton | Indications for use | Limitations | Sponsor |
| --- | --- | --- | --- | --- |
| (i) 0.91 | | Broiler chickens: For the prevention of coccidiosis caused by *Eimeria tenella, E. necatrix, E. acervulina, E. brunetti, E. mitis (mivati),* and *E. maxima.* Because diclazuril is effective against *E. maxima* later in its life cycle, subclinical intestinal lesions may be present for a short time after infection. Diclazuril was shown in studies to reduce lesion scores and improve performance and health of birds challenged with *E. maxima* | Feed continuously as the sole ration. Do not feed to birds producing eggs for human consumption | 058198 |
| (ii) 0.91 | Bacitracin methylenedisalicylate, 4 to 50 | Broiler chickens: For the prevention of coccidiosis caused by *Eimeria tenella, E. necatrix, E. acervulina, E. brunetti, E. mitis (mivati),* and *E. maxima,* and for increased rate of weight gain and improved feed efficiency. Because diclazuril is effective against *E. maxima* later in its life cycle, subclinical intestinal lesions may be present for a short time after infection. Diclazuril was shown in studies to reduce lesion scores and improve performance and health of birds challenged with *E. maxima* | Feed continuously as the sole ration. Do not feed to birds producing eggs for human consumption. Bacitracin methylenedisalicylate provided by No. 054771 in [§ 510.600(c) of this chapter](/on/2024-09-23/title-21/section-510.600#p-510.600(c)) | 058198 |
| (iii) 0.91 | Bambermycins, 1 to 2 | Broiler chickens: For the prevention of coccidiosis caused by *Eimeria tenella, E. necatrix, E. acervulina, E. brunetti, E. mitis (mivati),* and *E. maxima,* and for increased rate of weight gain and improved feed efficiency. Because diclazuril is effective against *E. maxima* later in its life cycle, subclinical intestinal lesions may be present for a short time after infection. Diclazuril was shown in studies to reduce lesion scores and improve performance and health of birds challenged with *E. maxima* | Feed continuously as the sole ration. Do not feed to birds producing eggs for human consumption. Bambermycins provided by No. 016592 in [§ 510.600(c) of this chapter](/on/2024-09-23/title-21/section-510.600#p-510.600(c)) | 058198 |

(2) *Turkeys.* For turkeys it is used as follows:

| Diclazuril grams/ton | Combination grams/ton | Indications for use | Limitations | Sponsor |
| --- | --- | --- | --- | --- |
| (i) 0.91 | | Growing turkeys: For the prevention of coccidiosis caused by *Eimeria adenoeides, E. gallopavonis,* and *E. meleagrimitis* | Feed continuously as the sole ration. Do not feed to breeding turkeys. Do not feed to birds producing eggs for human consumption | 058198 |
| (ii) 0.91 | Bacitracin methylenedisalicylate, 4 to 50 | Growing turkeys: For the prevention of coccidiosis caused by *Eimeria adenoeides, E. gallopavonis,* and *E. meleagrimitis,* and for increased rate of weight gain and improved feed efficiency | Feed continuously as the sole ration. Do not feed to breeding turkeys. Do not feed to birds producing eggs for human consumption. Bacitracin methylenedisalicylate as provided by No. 054771 in [§ 510.600(c) of this chapter](/on/2024-09-23/title-21/section-510.600#p-510.600(c)) | 058198 |
| (iii) 0.91 | Bambermycins 1 to 2 | Growing turkeys: For the prevention of coccidiosis caused by *Eimeria adenoeides, E. gallopavonis,* and *E. meleagrimitis,* and for improved feed efficiency | Feed continuously as the sole ration. Do not feed to breeding turkeys. Do not feed to birds producing eggs for human consumption. Bambermycins as provided by No. 016592 in [§ 510.600(c) of this chapter](/on/2024-09-23/title-21/section-510.600#p-510.600(c)) | 058198 |
| (iv) 0.91 | Bambermycins 2 | Growing turkeys: For the prevention of coccidiosis caused by *Eimeria adenoeides, E. gallopavonis,* and *E. meleagrimitis,* and for increased rate of weight gain and improved feed efficiency | Feed continuously as the sole ration. Do not feed to breeding turkeys. Do not feed to birds producing eggs for human consumption. Bambermycins as provided by No. 016592 in [§ 510.600(c) of this chapter](/on/2024-09-23/title-21/section-510.600#p-510.600(c)) | 058198 |

(3) Diclazuril may also be used in combination with virginiamycin as in [§ 558.635](/on/2024-09-23/title-21/section-558.635).

[[64 FR 35923](https://www.federalregister.gov/citation/64-FR-35923), July 2, 1999, as amended at [65 FR 50134](https://www.federalregister.gov/citation/65-FR-50134), Aug. 17, 2000; [66 FR 47962](https://www.federalregister.gov/citation/66-FR-47962), [47963](https://www.federalregister.gov/citation/66-FR-47963), Sept. 17, 2001; [66 FR 62917](https://www.federalregister.gov/citation/66-FR-62917), Dec. 4, 2001; [67 FR 34830](https://www.federalregister.gov/citation/67-FR-34830), May 16, 2002; [67 FR 47257](https://www.federalregister.gov/citation/67-FR-47257), July 18, 2002; [67 FR 48549](https://www.federalregister.gov/citation/67-FR-48549), July 25, 2002; [69 FR 9947](https://www.federalregister.gov/citation/69-FR-9947), Mar. 3, 2004; [72 FR 60552](https://www.federalregister.gov/citation/72-FR-60552), Oct. 25, 2007; [79 FR 10982](https://www.federalregister.gov/citation/79-FR-10982), Feb. 27, 2014; [79 FR 13545](https://www.federalregister.gov/citation/79-FR-13545), Mar. 11, 2014; [81 FR 17609](https://www.federalregister.gov/citation/81-FR-17609), Mar. 30, 2016; [81 FR 95004](https://www.federalregister.gov/citation/81-FR-95004), Dec. 27, 2016. Redesignated and amended at [84 FR 12497](https://www.federalregister.gov/citation/84-FR-12497), [12498](https://www.federalregister.gov/citation/84-FR-12498), Apr. 2, 2019; [87 FR 10970](https://www.federalregister.gov/citation/87-FR-10970), Feb. 28, 2022]