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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460

OFFICE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION

MEMORANDUM

Date: 17-November-2015

Subject: Carfentrazone-ethyl. Section 3 Registration for Application to Globe Artichoke, 

Asparagus, Mint, Psyllium, Quinoa, and Teff and Updating the Crop Group (CG) or 

Subgroup (CSG) Designation for Bulb Vegetables (CG 3-07); Fruiting Vegetables 

(CG 8-10); Citrus (CG 10-10); Pome Fruit (CG 11-10); Stone Fruit (CG 12-12); 

Caneberry (CSG 13-07A); Bushberry (CSG 13-07B); Fruit, Small Vine Climbing, 

Except Fuzzy Kiwifruit (CSG 13-07F); Berry, Low Growing (CSG 13-07G); Tree 

Nuts (CG 14-12); and Oilseed (CG 20). Dietary Exposure Assessment.

PC Codes: 128712 DP Barcode: D428859

Decision No.: 498511 Registration Nos.: 279-3194; 279-3241; 279-3242

Petition No.: 4E8337 Regulatory Action: Section 3

Risk Assessment Type: dietary Case No.: 7422

TXR No.: not applicable CAS No.: 128639-02-1

MRID No.: none 40 CFR: 180.515 

From/To: Tom Bloem, Chemist

Risk Assessment Branch 1/Health Effects Division (RAB1/HED; 7509P)

Through: Sumitra Biswas, Chemist, RAB6/HED

Doug Dotson, Ph.D., Chemist, RAB2/HED

Dietary Exposure Science Advisory Committee (DESAC) Secondary Review

George F. Kramer, Ph.D., Senior Chemist

RAB1/HED (7509P)

Executive Summary

Dietary (food and drinking water) exposure and risk assessments were conducted using the Dietary 

Exposure Evaluation Model - Food Consumption Intake Database (DEEM-FCID, ver. 3.16) which 

incorporates food consumption data from the United States Department of Agriculture (USDA) 

National Health and Nutrition Examination Survey, What We Eat in America (NHANES/WWEIA; 

2003-2008). The analysis was conducted in support of the proposed Section 3 registration for 

application of carfentrazone-ethyl to globe artichoke, asparagus, mint, psyllium, quinoa, and teff and 

the proposed updates to the crop definitions for several CGs and CSGs. 

The chronic analysis assumed tolerance-level residues or, if necessary, tolerance-level residues 

adjusted to account for the residues of concern for risk assessment, 100% crop treated, and 

modeled drinking water estimates (based on toxicological considerations, acute and cancer 

analyses are unnecessary). Since adequate processing studies have been submitted which indicate 

that tolerances in/on apple juice, citrus juice, grape juice, grape raisin, dried potato, dried prune, 
Carfentrazone-ethyl (128712) Dietary Exposure Assessment D428859

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prune juice, tomato paste, and tomato puree are unnecessary, the DEEMTM (ver 7.81) default 

processing factors for these commodities were reduced to 1. The DEEMTM (ver 7.81) default 

processing factors were retained for the remaining relevant commodities. The resulting chronic 

exposure estimates are not of concern to HED (≤78% chronic population adjusted dose (cPAD); 

children 1-2 years old were the most highly exposed subgroup). 

I. Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For chronic 

assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose 

that HED has concluded will result in no unreasonable adverse health effects). This dose is 

referred to as the PAD. The PAD is equivalent to the point of departure (POD, NOAEL, LOAEL, 

e.g.) divided by the required uncertainty or safety factors. For non-cancer chronic exposures, HED 

is concerned when estimated dietary risk exceeds 100% of the PAD. References that discuss the 

chronic risk assessments in more detail are available on the EPA/pesticides web site: “Available 

Information on Assessing Exposure from Pesticides, A User’s Guide,” 21-JUN-2000, web link: 

http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPP-2007-0780-0001; or see SOP 

99.6 (20-Aug-1999). The most recent dietary risk assessment for carfentrazone-ethyl was 

conducted by T. Bloem (D389977, 29-Feb-2012).

II. Residue Information

Residues of Concern in Plants (primary and rotational), Livestock, and Water: Table 1 is a 

summary of the residues of concern for tolerance enforcement and risk assessment in plants, 

livestock, fish, and water. For further information concerning these decisions, see the following

human-health risk assessment - D425574, T. Bloem et al., ??-???-2015. 

Table 1: Summary of Residues to be Included in the Risk Assessment and Tolerance Expression.

Matrix Residues of Concern for 

Risk Assessment

Residues of Concern for 

Tolerance Assessment

plants

Primary Crops (cereal grain, cotton, grass, 

mint, asparagus, teff, quinoa, psyllium) carfentrazone-ethyl and CR-75

carfentrazone-ethyl and CR-75

Primary Crop (nongrass animal feed) carfentrazone-ethyl, CR-75, and CR-48

Primary Crops (remaining proposed/ 

registered crops)

carfentrazone-ethyl, CR-75, CR-48, 3-OH-F8426-

BAc, F8426-BAc, and Me-3-OH-F8426-BAc

Rotational Crops

carfentrazone-ethyl and CR-75; the MARC also 

expressed concern for the residues of the benzoic 

acid compounds if the levels found are similar to 

or greater than the parent and the metabolite

livestock (ruminant poultry) carfentrazone-ethyl and CR-75

fish/shellfish carfentrazone-ethyl and CR-75

water carfentrazone-ethyl, CR-75, and F8426-CAc not applicable

HED Recommended Tolerances: Table 2 is a summary of the HED-recommended tolerances 

for the combined residues of carfentrazone-ethyl and carfentrazone-chloropropionic acid (CR75; expressed in parent equivalents) resulting from the current action. HED notes that proposed 

changes to the banana and cereal grain tolerances are based on recommendations made as part of 

scoping assessment submitted in support of registration review (D382666, K. Lowe et al., 9-Feb2011). With the establishment of the tolerances listed in Table 2, the following tolerances will

be deleted: barley, bran; barley, flour; berry group 13; borage; caneberry subgroup 13A; canola; 

coconut; corn, field, forage; corn, sweet, forage; corn, sweet, kernel plus cob with husk removed; 

cotton, undelinted seed; cotton, hulls; cotton, meal; cotton, refined oil; crambe, seed; flax, seed; 
Carfentrazone-ethyl (128712) Dietary Exposure Assessment D428859

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fruit, citrus, group 10; fruit, pome, group 11; fruit, stone, group 12; grain, cereal, forage, fodder 

and straw group 16, except corn and sorghum, forage; grain, cereal, forage, fodder and straw, 

group 16, hay; grain, cereal, forage, fodder and straw, group 16, stover; grain, cereal, forage, 

fodder and straw, group 16, except rice, straw; grain, cereal, group 15; grain, cereal, stover; grain 

cereal, straw; grape; juneberry; lingonberry; millet, flour; mustard, seed; nut, tree, group 14; oat, 

flour; okra; pistachio; pummelo; rapeseed, seed; rice, hulls; rice, straw; rye, bran; rye, flour; 

safflower, seed; salal; sorghum, forage; sorghum, sweet; strawberry; sunflower, seed; vegetable, 

bulb, group 3; vegetable, fruiting, group 8; wheat, bran; wheat, flour; wheat, germ; wheat, 

middlings; and wheat, shorts.

Table 2: Tolerance Summary

Commodity HED-Recommended Tolerance (ppm)

artichoke, globe 0.10

asparagus 0.10

peppermint, tops 0.10

spearmint, tops 0.10

teff, grain 0.25

teff, forage 1.0

teff, hay 0.30

teff, straw 3.0

vegetable, bulb, group 3-07 0.10

vegetable, fruiting, group 8-10 0.10

fruit, citrus, group 10-10 0.10

fruit, pome, group 11-10 0.10

fruit, stone, group 12-12 0.10

caneberry subgroup 13-07A 0.10

bushberry subgroup 13-07B 0.10

fruit, small vine climbing, subgroup 13-07F, except Fuzzy kiwifruit 0.10

berry, low growing, subgroup 13-07G 0.10

nut, tree, group 14-12 0.10

rapeseed subgroup 20A 0.10

sunflower subgroup 20B 0.10

cottonseed subgroup 20C 0.20

quinoa, grain 0.10

psyllium, seed 0.10

banana 0.10

grain, cereal, group 16, forage 1.0

grain, cereal, group 16, hay 0.30

grain, cereal, group 16, stover 0.80

grain, cereal, group 16, straw 3.0

Plant Residues Incorporated into the Chronic Dietary Exposure Assessment: The chronic 

analysis assumed 100% crop treated. Since adequate processing studies have been submitted 

which indicate that tolerances in/on apple juice, citrus juice, grape juice, grape raisin, dried 

potato, dried prune, prune juice, tomato paste, and tomato puree are unnecessary, the DEEMTM

(ver 7.81) default processing factors for these commodities were reduced to 1. The DEEMTM

(ver 7.81) default processing factors were retained for the remaining relevant commodities. The 

following paragraphs and Table 2 are summaries of the residues incorporated into the chronic 

dietary exposure analysis.

Cereal grain, Cotton, Mint, Asparagus, Teff, Quinoa, and Psyllium: For cereal grain, cotton, 
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mint, asparagus, teff, quinoa, and psyllium, the residues of concern for tolerance enforcement 

and risk assessment are identical. Therefore, the chronic dietary exposure analysis assumed 

tolerance level residues for these crops. As indicated above, the small grain (barley, millet, oat, 

rye, and wheat) processed commodities are being deleted and therefore the raw agricultural 

commodity (RAC) tolerances were assumed for the processed commodities (D351363, T. 

Bloem, 14-May-2008). 

Nongrass animal feed: The only food commodity associated with the nongrass animal feed crop 

group is alfalfa seed. The alfalfa field trial data resulted in a maximum combined carfentrazoneethyl, CR-75, and CR-48 residue of 2.847 ppm in/on alfalfa seed (48397305.der.docx). Since 

this is lower than the recommended 15 ppm tolerance for combined carfentrazone-ethyl and CR75, the assessment assumed tolerance level residues. 

Remaining Registered Crops: For the remaining crops, the residues of concern for risk 

assessment are carfentrazone-ethyl, CR-75, CR-48, 3-OH-F8426-BAc, F8426-BAc, and Me-3-

OH-F8426-BAc. The petitioner has not monitored for residues of 3-OH-F8426-BAc, F8426-

BAc, and/or Me-3-OH-F8426-BAc in the majority of the field trial studies. Therefore, HED 

estimated residues for these compounds using the following maximum residue ratios from the 

confined rotational crop study: (1) 3-OH-F8426-BAc:carfentrazone-ethyl - 12.0; (2) F8426-

BAc:carfentrazone-ethyl - 3.8; and (3) Me-3-OH-F8426-BAc:carfentrazone-ethyl - 4.8. HED 

concludes that the residue estimates for 3-OH-F8426-BAc, F8426-BAc, and/or Me-3-OHF8426-BAc are conservative for the following reasons: (1) LOD residues for carfentrazone-ethyl 

were assumed (residues of carfentrazone-ethyl were <LOD); (2) maximum residue ratios from 

the confined study were assumed; (3) residues of 3-OH-F8426-BAc were monitored in the 

legume vegetable and sugarcane field trial studies with residues <LOD (LOD 0.03 ppm) in/on 

pea/bean/sugarcane and <0.05 ppm in/on legume vegetable foliage; these residues are much less 

than the residue estimate used in the dietary exposure analysis of 0.36 ppm.

Fish/Shellfish: For fish/shellfish, the residues of concern for tolerance enforcement and risk 

assessment are identical. Therefore, the chronic dietary exposure analysis assumed tolerance 

level fish/shellfish residues. HED notes that these tolerances are based on a magnitude of the 

residue study which employed a single application at 0.30 lb ai/surface acre (1.5x the registered 

aquatic and rice application rate; D294823, T. Bloem, 15-Jul-2004). 

Livestock: Since the livestock maximum reasonable dietary burdens (MRDBs) for risk 

assessment are only slightly higher than the MRDBs for tolerance enforcement and since these 

dietary burdens are based on tolerance level residues and 100% crop treated, HED concludes that 

the livestock tolerances may be used in the chronic dietary exposure analysis. 
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Table 3. Summary of Carfentrazone-ethyl Tolerances and Combined Residues of Concern 

Commodity Tolerance 

(ppm) application scenario

residue (ppm)

F84261 CR-751 CR-481 3-OHF8426-BAc2 F8426-BAc Me-3-OHF8426-BAc combined

cereal grain, grain (including processed commodities; 

except rice and sorghum grain) 0.10

foliar or, soil-directed 

and foliar

residues of concern for risk assessment the same as for tolerance 

expressions; tolerance level residues assumed

rice grain (including processed commodities) 1.3

grain sorghum grain (including processed commodities) 0.25

cottonseed oil 0.20

asparagus 0.10

mint 0.10

teff, grain 0.25

quinoa, grain 0.10

psyllium, grain 0.10

alfalfa seed 15

Residues of concern for risk assessment are carfentrazone-ethyl, CR-75, and CR-48; the 

alfalfa field trial data resulted in a maximum combined carfentrazone-ethyl, CR-75, and CR48 residue of 2.847 ppm in/on alfalfa seed (48397305.der.docx). Since this is lower than the 

recommended 15 ppm tolerance, the assessment assumed tolerance level residues. 

vegetable, root and tuber, group 01 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

vegetable, leaves of root and tuber, group 023 0.10 soil-directed 0.02 0.04 0.05 0.24 0.08 0.10 0.52

vegetable, bulb, group 03-07 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

vegetable, leafy, except brassica, group 04 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

vegetable, brassica leafy, group 05 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

vegetable, legume, group 062 0.10 soil-directed 0.03 0.03 0.03 0.03 0.11 0.14 0.38

vegetable, fruiting, group 08-10 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

vegetable, cucurbit, group 09 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

fruit, citrus, group 10-10 0.10 soil-directed 0.01 0.03 0.03 0.12 0.04 0.05 0.28

fruit, pome, group 11-10 0.10 soil-directed 0.01 0.03 0.03 0.12 0.04 0.05 0.28

fruit, stone, group 12-12 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

caneberry subgroup 13-07A 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

bushberry subgroup 13-07B 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

fruit, small vine climbing, subgroup 13-07F, except 

Fuzzy kiwifruit 

0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

berry, low growing, subgroup 13-07G 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

nut, tree, group 14-12 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

herbs and spices group 194 2.0 soil-directed 0.44 0.44 0.44 5.28 1.67 2.11 10.38

oilseed group 20 (except cotton) 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

acerola 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71
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Table 3. Summary of Carfentrazone-ethyl Tolerances and Combined Residues of Concern 

Commodity Tolerance 

(ppm) application scenario

residue (ppm)

F84261 CR-751 CR-481 3-OHF8426-BAc2 F8426-BAc Me-3-OHF8426-BAc combined

artichoke, globe 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

avocado 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

banana/plantain 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

cacao (cocoa bean) 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

cactus 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

canistel 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

cherimoya 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

coffee 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

date 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

feijoa 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

fig 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

guava 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

hop, dried cones5 0.10 soil-directed 0.05 0.05 0.05 0.60 0.19 0.24 1.18

jaboticaba 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

kiwifruit 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

longan 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

lychee 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

mango 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

mulberry 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

olive 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

palm heart 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

palm heart, leaves 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

papaya 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

passionfruit 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

pawpaw 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

peanut, nutmeat6 0.10 soil-directed/harvest-aid 0.03 0.03 0.04 0.36 0.11 0.14 0.72

persimmon 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

pomegranate 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

sapote, mamey 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

sorghum, sweet 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

soursop 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

spanish lime 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

starfruit 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71
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Table 3. Summary of Carfentrazone-ethyl Tolerances and Combined Residues of Concern 

Commodity Tolerance 

(ppm) application scenario

residue (ppm)

F84261 CR-751 CR-481 3-OHF8426-BAc2 F8426-BAc Me-3-OHF8426-BAc combined

sugar apple 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

sugarcane7 0.15 soil-directed/harvest-aid 0.03 0.07 0.07 0.03 0.11 0.14 0.45

tea 0.10 soil-directed 0.03 0.03 0.03 0.36 0.11 0.14 0.71

meat, byproducts (cattle, goat, hog, horse, and sheep) 0.10

not applicable residues of concern for risk assessment the same as for tolerance expressions; 

tolerance level residues assumed

meat (cattle, goat, hog, horse, and sheep) 0.10

fat (cattle, goat, hog, horse, and sheep) 0.10

meat, byproducts (poultry) 0.10

milk 0.05

fish/shellfish 0.30

1 Residues of carfentrazone-ethyl (F8426), CR-75, and CR-48 were <LOD for all crops where only soil-directed applications were proposed/registered (except hops and leaves of root 

and tuber vegetables; see below); LOD = 0.01 ppm for F8426 in citrus and pome fruit, and ≤0.03 ppm for remaining crops/anlaytes.

2 Residues of 3-OH-F8426-BAc were monitored in the legume vegetable (pea/bean and foliage) and sugarcane field trial studies; residues were <LOD (LOD  0.03 ppm) in 

pea/bean/sugarcane and <LOQ (LOQ = 0.05 ppm) in legume vegetable foliage.

3 Residues in leaves of root and tuber were >LOD but <LOQ; maximum residue used for calculation of combined residues.

4 Residues in leafy vegetables (except brassica) translated to the herb and spice crop group with adjustment for percent dry matter (6.1% for leafy vegetables and 90% for herb and spices).

5 Residues in hop were reported as <LOQ; therefore, residues at the LOQ were assumed.

6 Residues of carfentrazone-ethyl, CR-75, and CR-48 were <LOD in/on peanut nutmeat following soil directed and/or harvest-aid application (LOD = 0.01-0.03 ppm for carfentrazoneethyl, 0.02-0.03 ppm for CR-75, and 0.03-0.04 ppm for CR-48)

7 Residues of carfentrazone-ethyl and 3-OH-F8426-BAc were ≤LOD in/on sugarcane following soil directed and/or harvest-aid application (LOD = 0.02-0.03 ppm); residues of CR-75

and CR-48 were ≤0.07 ppm and ≤0.07 ppm, respectively, following soil directed and harvest-aid application.
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III. Drinking Water Data

Comsoderomg all registered/proposed uses, the rice and caneberry application scenarios yield the 

highest surface water and ground water estimated drinking water concentrations (EDWCs; 

D425572, R. Shamblen, 16-Sep-2015); the EDWCs for these uses are summarized in Table 4. 

The surface water EDWCs resulting from the rice use were generated using the Tier I Rice 

Model. The groundwater EDWC from the caneberry use was generated using Pesticide Root 

Zone Model for Ground Water (PRZM-GW). Additional information concerning these models 

are available at the EPA internet site: http://www.epa.gov/oppefed1/models/water/. The EDWCs 

from the rice use are the highest and were incorporated into the chronic dietary exposure analysis 

(“water, direct, all sources” and “water, indirect, all sources”). 

Table 4: EWDCs.

Drinking Water Source (Model) Application Rate Value for Chronic Assessment (μg/L)

surface water (Tier I Rice Model) rice, wild rice (0.20 lbs ai/acre) 86

ground water (PRZM-GW) caneberries (0.4 lbs ai/acre) 43.9

IV. DEEM-FCIDTM Program and Consumption Information

The carfentrazone-ethyl chronic dietary exposure assessment was conducted using the DEEMFCID (ver. 3.16) which incorporates 2003-2008 consumption data from USDA’s 

NHANES/WWEIA. The data are based on the reported consumption of more than 20,000 

individuals over two non-consecutive survey days. Foods “as consumed” (e.g., apple pie) are 

linked to EPA-defined food commodities (e.g., apples, peeled fruit - cooked; fresh or N/S; baked; 

or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files 

developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consumption data 

are averaged for the entire U.S. population and within population subgroups. Based on analysis 

of the 2003-2008 WWEIA consumption data, which took into account dietary patterns and survey 

respondents, HED concluded that it is most appropriate to report risk for the following population 

subgroups: the general U.S. population, all infants (<1 year old), children 1-2, children 3-5, 

children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50-99 years old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food or foodform (e.g., orange or orange juice) on the food commodity residue list is multiplied by the 

average daily consumption estimate for that food/food form to produce a residue intake estimate. 

The resulting residue intake estimate for each food/food form is summed with the residue intake 

estimates for all other food/food forms on the commodity residue list to arrive at the total 

average estimated exposure. Exposure is expressed in mg/kg body weight/day and as a percent 

of the cPAD. This procedure is performed for each population subgroup.
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V. Toxicological Information

Table 5 is a summary of the toxicological doses and endpoints for carfentrazone-ethyl dietary 

exposure assessment. Based on the toxicological database and residue assumptions, RAB1 

concluded that the Food Quality Protection Act (FQPA) safety factor (SF) may be reduced to 1x. 

For a complete discussion concerning these conclusions, see the human-health risk assessment 

D??? (T. Bloem et al., ??-Nov-2015).

Table 5: Summary of Toxicological Doses and Endpoints for Carfentrzone-Ethyl for Use in Dietary, NonOccupational, and Occupational Human Health Risk Assessments

Exposure/ 

Scenario Point of Departure Uncertainty/FQPA Safety Factors

RfD, PAD, Level of 

Concern for Risk 

Assessment

Study and Toxicological Effects

Acute Dietary (all 

populations)

No appropriate toxicological effects attributable to a single dose were observed. Therefore, a dose and endpoint were 

not identified for this risk assessment.

Chronic Dietary 

(All Populations)

NOEL= 

3.0 mg/kg/day

UFA= 10x 

UFH=10x 

FQPA SF= 1x

cRfD = 0.03 mg/kg/day

aPAD = 0.03mg/kg/day

Chronic toxicity - rats: 

LOEL = 12 mg/kg/day based on liver 

histopathology (increases in microscopic red 

fluorescence and pigmentation) and increased 

urinary porphyrin levels in both sexes

Cancer (oral, 

dermal, inhalation)Classification: “Not likely to be carcinogen,” cancer risk assessment is not required

Point of Departure (POD) = A data point or an estimated point that is derived from observed dose-response data and used to 

mark the beginning of extrapolation to determine risk associated with lower environmentally relevant human exposures. NOAEL 

= no observed adverse effect level. LOAEL = lowest observed adverse effect level. UF = uncertainty factor. UFA = 

extrapolation from animal to human (interspecies). UFH = potential variation in sensitivity among members of the human 

population (intraspecies). FQPA SF = FQPA Safety Factor. PAD = population adjusted dose (a = acute, c = chronic). RfD = 

reference dose. 

VI. Results/Discussion & Conclusions

The unrefined chronic analysis resulted in risk estimates that are not of concern to HED (see 

Table 6; ≤78% cPAD; children 1-2 years old were the most highly exposed subgroup). 

Table 6: Summary of the Chronic Dietary Exposures and Risks.

Population cPAD (mg/kg/day) Exposure (mg/kg/day) %cPAD

General U.S. Population

0.03

0.007972 27

All Infants (< 1 year old) 0.017437 58

Children 1-2 years old 0.023432 78

Children 3-5 years old 0.017502 58

Children 6-12 years old 0.010253 34

Youth 13-19 years old 0.006020 20

Adults 20-49 years old 0.006616 22

Adults 50-99 years old 0.006598 22

Females 13-49 years old 0.006453 22
Carfentrazone-ethyl (128712) Dietary Exposure and Risk Assessment D428859

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VII. Characterization of Inputs/Outputs

The chronic analysis is conservative and could be refined through the incorporation of maximum 

or average field trial residues, residue monitoring data, percent crop treated estimates, and/or 

empirical processing factors. 

VIII. Conclusions

The chronic analysis assumed tolerance-level residues or, if necessary, tolerance-level residues 

adjusted to account for the residues of concern for risk assessment, 100% crop treated, and 

modeled drinking water estimates. Since adequate processing studies have been submitted 

which indicate that tolerances in/on apple juice, citrus juice, grape juice, grape raisin, dried 

potato, dried prune, prune juice, tomato paste, and tomato puree are unnecessary, the DEEMTM

(ver 7.81) default processing factors for these commodities were reduced to 1. The DEEMTM

(ver 7.81) default processing factors were retained for the remaining relevant commodities. The 

resulting chronic exposure estimates are not of concern to HED (≤78% cPAD; children 1-2 years 

old were the most highly exposed subgroup). 

Attachment 1: DEEM-FCIDTM chronic exposure estimates

Attachment 2: DEEM-FCIDTM chronic residue file
Carfentrazone-ethyl (128712) Dietary Exposure and Risk Assessment D428859

Page 11 of 20

Attachment 1: DEEM-FCIDTM chronic exposure estimates

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for CARFENTRAZONE-ETHYL NHANES 2003-2008 2-day

Residue file name: C:\Users\tbloem\Documents\work\carfentrazone-ethyl\artichoke, 

asparagus, mint, teff, and new crop group tolerances\128712C.R08

 Adjustment factor #2 NOT used.

Analysis Date 09-18-2015/12:21:49 Residue file dated: 09-18-2015/12:21:27

Reference dose (RfD, Chronic) = .03 mg/kg bw/day

COMMENT 1: FQPA SF = 1x

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- ----------------

Total US Population 0.007972 26.6%

Hispanic 0.008829 29.4%

Non-Hisp-White 0.007822 26.1%

Non-Hisp-Black 0.007118 23.7%

Non-Hisp-Other 0.009788 32.6%

Nursing Infants 0.009367 31.2%

Non-Nursing Infants 0.021041 70.1%

Female 13+ PREG 0.007304 24.3%

Children 1-6 0.019087 63.6%

Children 7-12 0.009528 31.8%

Male 13-19 0.006136 20.5%

Female 13-19/NP 0.005915 19.7%

Male 20+ 0.006549 21.8%

Female 20+/NP 0.006636 22.1%

Seniors 55+ 0.006560 21.9%

All Infants 0.017437 58.1%

Female 13-50 0.006456 21.5%

Children 1-2 0.023432 78.1%

Children 3-5 0.017502 58.3%

Children 6-12 0.010253 34.2%

Youth 13-19 0.006020 20.1%

Adults 20-49 0.006616 22.1%

Adults 50-99 0.006598 22.0%

Female 13-49 0.006453 21.5%

-------------------------------------------------------------------------------
Carfentrazone-ethyl (128712) Dietary Exposure and Risk Assessment D428859

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Attachment 2: DEEM-FCIDTM chronic residue file

Filename: C:\Users\tbloem\Documents\work\carfentrazone-ethyl\artichoke, asparagus, 

mint, teff, and new crop group tolerances\128712C.R08

Chemical: carfentrazone-ethyl

RfD(Chronic): .03 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): 0 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day

Date created/last modified: 09-18-2015/12:21:27 Program ver. 3.16, 03-08-d

Comment: FQPA SF = 1x

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

9500001000 O Acerola 0.710000 1.000 1.000 

9500016000 O Artichoke, globe 0.710000 1.000 1.000 

9500019000 O Asparagus 0.710000 1.000 1.000 

9500020000 O Avocado 0.710000 1.000 1.000 

9500023000 O Banana 0.710000 1.000 1.000 

9500024000 O Banana, dried 0.710000 3.900 1.000 

9500024001 O Banana, dried-babyfood 0.710000 3.900 1.000 

9500023001 O Banana-babyfood 0.710000 1.000 1.000 

9500073000 O Cactus 0.710000 1.000 1.000 

9500074000 O Canistel 0.710000 1.000 1.000 

9500089000 O Cherimoya 0.710000 1.000 1.000 

9500109000 O Cocoa bean, chocolate 0.710000 1.000 1.000 

9500110000 O Cocoa bean, powder 0.710000 1.000 1.000 

9500112000 O Coconut, dried 0.710000 2.100 1.000 

9500111000 O Coconut, meat 0.710000 1.000 1.000 

9500111001 O Coconut, meat-babyfood 0.710000 1.000 1.000 

9500113000 O Coconut, milk 0.710000 1.000 1.000 

9500114000 O Coconut, oil 0.710000 1.000 1.000 

9500116000 O Coffee, instant 0.710000 1.000 1.000 

9500115000 O Coffee, roasted bean 0.710000 1.000 1.000 

9500141000 O Date 0.710000 1.000 1.000 

9500151000 O Feijoa 0.710000 1.000 1.000 

9500153000 O Fig 0.710000 1.000 1.000 

9500154000 O Fig, dried 0.710000 1.000 1.000 

9500177000 O Grape, leaves 0.710000 1.000 1.000 

9500178000 O Grape, raisin 0.710000 1.000 1.000 

9500183000 O Guava 0.710000 1.000 1.000 

9500183001 O Guava-babyfood 0.710000 1.000 1.000 

9500188000 O Hop 1.180000 1.000 1.000 

9500209000 O Longan 0.710000 1.000 1.000 

9500211000 O Lychee 0.710000 1.000 1.000 

9500212000 O Lychee, dried 0.710000 1.850 1.000 

9500215000 O Mango 0.710000 1.000 1.000 

9500216000 O Mango, dried 0.710000 1.000 1.000 

9500217000 O Mango, juice 0.710000 1.000 1.000 

9500217001 O Mango, juice-babyfood 0.710000 1.000 1.000 

9500215001 O Mango-babyfood 0.710000 1.000 1.000 

9500235000 O Olive 0.710000 1.000 1.000 

9500236000 O Olive, oil 0.710000 1.000 1.000 

9500243000 O Palm heart, leaves 0.710000 1.000 1.000 

9500244000 O Palm, oil 0.710000 1.000 1.000 

9500244001 O Palm, oil-babyfood 0.710000 1.000 1.000 

9500245000 O Papaya 0.710000 1.000 1.000 

9500246000 O Papaya, dried 0.710000 1.800 1.000 

9500247000 O Papaya, juice 0.710000 1.500 1.000 

9500245001 O Papaya-babyfood 0.710000 1.000 1.000 

9500252000 O Passionfruit 0.710000 1.000 1.000 

9500253000 O Passionfruit, juice 0.710000 1.000 1.000 

9500253001 O Passionfruit, juice-babyfood 0.710000 1.000 1.000 
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9500252001 O Passionfruit-babyfood 0.710000 1.000 1.000 

9500254000 O Pawpaw 0.710000 1.000 1.000 

9500263000 O Peanut 0.720000 1.000 1.000 

9500264000 O Peanut, butter 0.720000 1.890 1.000 

9500265000 O Peanut, oil 0.720000 1.000 1.000 

9500275000 O Peppermint 0.100000 1.000 1.000 

9500276000 O Peppermint, oil 0.100000 1.000 1.000 

9500277000 O Persimmon 0.710000 1.000 1.000 

9500283000 O Plantain 0.710000 1.000 1.000 

9500284000 O Plantain, dried 0.710000 3.900 1.000 

9500289000 O Pomegranate 0.710000 1.000 1.000 

9500306000 O Psyllium, seed 0.100000 1.000 1.000 

9500311000 O Quinoa, grain 0.100000 1.000 1.000 

9500333000 O Sapote, Mamey 0.710000 1.000 1.000 

9500346000 O Soursop 0.710000 1.000 1.000 

9500351000 O Spanish lime 0.710000 1.000 1.000 

9500352000 O Spearmint 0.100000 1.000 1.000 

9500353000 O Spearmint, oil 0.100000 1.000 1.000 

9500358000 O Starfruit 0.710000 1.000 1.000 

9500361000 O Sugar apple 0.710000 1.000 1.000 

9500363000 O Sugarcane, molasses 0.450000 1.000 1.000 

9500363001 O Sugarcane, molasses-babyfood 0.450000 1.000 1.000 

9500362000 O Sugarcane, sugar 0.450000 1.000 1.000 

9500362001 O Sugarcane, sugar-babyfood 0.450000 1.000 1.000 

9500372000 O Tea, dried 0.710000 1.000 1.000 

9500373000 O Tea, instant 0.710000 1.000 1.000 

9500373500 O Teff, flour 0.250000 1.000 1.000 

0103015000 1CD Arrowroot, flour 0.710000 1.000 1.000 

0103015001 1CD Arrowroot, flour-babyfood 0.710000 1.000 1.000 

0103017000 1CD Artichoke, Jerusalem 0.710000 1.000 1.000 

0101050000 1AB Beet, garden, roots 0.710000 1.000 1.000 

0101050001 1AB Beet, garden, roots-babyfood 0.710000 1.000 1.000 

0101052000 1A Beet, sugar 0.710000 1.000 1.000 

0101053000 1A Beet, sugar, molasses 0.710000 1.000 1.000 

0101053001 1A Beet, sugar, molasses-babyfood 0.710000 1.000 1.000 

0101052001 1A Beet, sugar-babyfood 0.710000 1.000 1.000 

0101067000 1AB Burdock 0.710000 1.000 1.000 

0101078000 1AB Carrot 0.710000 1.000 1.000 

0101079000 1AB Carrot, juice 0.710000 1.000 1.000 

0101078001 1AB Carrot-babyfood 0.710000 1.000 1.000 

0103082000 1CD Cassava 0.710000 1.000 1.000 

0103082001 1CD Cassava-babyfood 0.710000 1.000 1.000 

0101084000 1AB Celeriac 0.710000 1.000 1.000 

0101100000 1AB Chicory, roots 0.710000 1.000 1.000 

0103139000 1CD Dasheen, corm 0.710000 1.000 1.000 

0103166000 1CD Ginger 0.710000 1.000 1.000 

0103167000 1CD Ginger, dried 0.710000 1.000 1.000 

0103166001 1CD Ginger-babyfood 0.710000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.710000 1.000 1.000 

0101190000 1AB Horseradish 0.710000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.710000 1.000 1.000 

0101251000 1AB Parsnip 0.710000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.710000 1.000 1.000 

0103296000 1C Potato, chips 0.710000 1.000 1.000 

0103297000 1C Potato, dry (granules/ flakes) 0.710000 1.000 1.000 

0103297001 1C Potato, dry (granules/ flakes)-b 0.710000 1.000 1.000 

0103298000 1C Potato, flour 0.710000 1.000 1.000 

0103298001 1C Potato, flour-babyfood 0.710000 1.000 1.000 

0103300000 1C Potato, tuber, w/o peel 0.710000 1.000 1.000 

0103300001 1C Potato, tuber, w/o peel-babyfood 0.710000 1.000 1.000 

0103299000 1C Potato, tuber, w/peel 0.710000 1.000 1.000 

0103299001 1C Potato, tuber, w/peel-babyfood 0.710000 1.000 1.000 
Carfentrazone-ethyl (128712) Dietary Exposure and Risk Assessment D428859

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0101316000 1AB Radish, Oriental, roots 0.710000 1.000 1.000 

0101314000 1AB Radish, roots 0.710000 1.000 1.000 

0101327000 1AB Rutabaga 0.710000 1.000 1.000 

0101331000 1AB Salsify, roots 0.710000 1.000 1.000 

0103366000 1CD Sweet potato 0.710000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.710000 1.000 1.000 

0103371000 1CD Tanier, corm 0.710000 1.000 1.000 

0103387000 1CD Turmeric 0.710000 1.000 1.000 

0101388000 1AB Turnip, roots 0.710000 1.000 1.000 

0103407000 1CD Yam bean 0.710000 1.000 1.000 

0103406000 1CD Yam, true 0.710000 1.000 1.000 

0200051000 2 Beet, garden, tops 0.520000 1.000 1.000 

0200101000 2 Chicory, tops 0.520000 1.000 1.000 

0200140000 2 Dasheen, leaves 0.520000 1.000 1.000 

0200317000 2 Radish, Oriental, tops 0.520000 1.000 1.000 

0200315000 2 Radish, tops 0.520000 1.000 1.000 

0200332000 2 Salsify, tops 0.520000 1.000 1.000 

0302103000 3B Chive, fresh leaves 10.380000 1.000 1.000 

0301165000 3A Garlic, bulb 0.710000 1.000 1.000 

0301165001 3A Garlic, bulb-babyfood 0.710000 1.000 1.000 

0302198000 3B Leek 0.710000 1.000 1.000 

0301237000 3A Onion, bulb 0.710000 1.000 1.000 

0301238000 3A Onion, bulb, dried 0.710000 9.000 1.000 

0301238001 3A Onion, bulb, dried-babyfood 0.710000 9.000 1.000 

0301237001 3A Onion, bulb-babyfood 0.710000 1.000 1.000 

0302239000 3B Onion, green 0.710000 1.000 1.000 

0301338000 3A Shallot, bulb 0.710000 1.000 1.000 

0302338500 3B Shallot, fresh leaves 0.710000 1.000 1.000 

0401005000 4A Amaranth, leafy 0.710000 1.000 1.000 

0401018000 4A Arugula 0.710000 1.000 1.000 

0402076000 4B Cardoon 0.710000 1.000 1.000 

0402085000 4B Celery 0.710000 1.000 1.000 

0402086000 4B Celery, juice 0.710000 1.000 1.000 

0402085001 4B Celery-babyfood 0.710000 1.000 1.000 

0402087000 4B Celtuce 0.710000 1.000 1.000 

0401104000 4A Chrysanthemum, garland 0.710000 1.000 1.000 

0401133000 4A Cress, garden 0.710000 1.000 1.000 

0401134000 4A Cress, upland 0.710000 1.000 1.000 

0401138000 4A Dandelion, leaves 0.710000 1.000 1.000 

0401150000 4A Endive 0.710000 1.000 1.000 

0402152000 4B Fennel, Florence 0.710000 1.000 1.000 

0401204000 4A Lettuce, head 0.710000 1.000 1.000 

0401205000 4A Lettuce, leaf 0.710000 1.000 1.000 

0401248000 4A Parsley, leaves 0.710000 1.000 1.000 

0401313000 4A Radicchio 0.710000 1.000 1.000 

0402322000 4B Rhubarb 0.710000 1.000 1.000 

0401355000 4A Spinach 0.710000 1.000 1.000 

0401355001 4A Spinach-babyfood 0.710000 1.000 1.000 

0402367000 4B Swiss chard 0.710000 1.000 1.000 

0501061000 5A Broccoli 0.710000 1.000 1.000 

0502063000 5B Broccoli raab 0.710000 1.000 1.000 

0501062000 5A Broccoli, Chinese 0.710000 1.000 1.000 

0501061001 5A Broccoli-babyfood 0.710000 1.000 1.000 

0501064000 5A Brussels sprouts 0.710000 1.000 1.000 

0501069000 5A Cabbage 0.710000 1.000 1.000 

0502070000 5B Cabbage, Chinese, bok choy 0.710000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 0.710000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 0.710000 1.000 1.000 

0501083000 5A Cauliflower 0.710000 1.000 1.000 

0502117000 5B Collards 0.710000 1.000 1.000 

0502194000 5B Kale 0.710000 1.000 1.000 

0501196000 5A Kohlrabi 0.710000 1.000 1.000 
Carfentrazone-ethyl (128712) Dietary Exposure and Risk Assessment D428859

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0502229000 5B Mustard greens 0.710000 1.000 1.000 

0502318000 5B Rape greens 0.710000 1.000 1.000 

0502389000 5B Turnip, greens 0.710000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.380000 1.000 1.000 

0603030000 6C Bean, black, seed 0.380000 1.000 1.000 

0603032000 6C Bean, broad, seed 0.380000 1.000 1.000 

0602031000 6B Bean, broad, succulent 0.380000 1.000 1.000 

0603034000 6C Bean, cowpea, seed 0.380000 1.000 1.000 

0602033000 6B Bean, cowpea, succulent 0.380000 1.000 1.000 

0603036000 6C Bean, kidney, seed 0.380000 1.000 1.000 

0603038000 6C Bean, lima, seed 0.380000 1.000 1.000 

0602037000 6B Bean, lima, succulent 0.380000 1.000 1.000 

0603039000 6C Bean, mung, seed 0.380000 1.000 1.000 

0603040000 6C Bean, navy, seed 0.380000 1.000 1.000 

0603041000 6C Bean, pink, seed 0.380000 1.000 1.000 

0603042000 6C Bean, pinto, seed 0.380000 1.000 1.000 

0601043000 6A Bean, snap, succulent 0.380000 1.000 1.000 

0601043001 6A Bean, snap, succulent-babyfood 0.380000 1.000 1.000 

0603099000 6C Chickpea, flour 0.380000 1.000 1.000 

0603098000 6C Chickpea, seed 0.380000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.380000 1.000 1.000 

0603182000 6C Guar, seed 0.380000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.380000 1.000 1.000 

0603203000 6C Lentil, seed 0.380000 1.000 1.000 

0603256000 6C Pea, dry 0.380000 1.000 1.000 

0603256001 6C Pea, dry-babyfood 0.380000 1.000 1.000 

0601257000 6A Pea, edible podded, succulent 0.380000 1.000 1.000 

0603258000 6C Pea, pigeon, seed 0.380000 1.000 1.000 

0602259000 6B Pea, pigeon, succulent 0.380000 1.000 1.000 

0602255000 6B Pea, succulent 0.380000 1.000 1.000 

0602255001 6B Pea, succulent-babyfood 0.380000 1.000 1.000 

0603348000 6C Soybean, flour 0.380000 1.000 1.000 

0603348001 6C Soybean, flour-babyfood 0.380000 1.000 1.000 

0600350000 6 Soybean, oil 0.380000 1.000 1.000 

0600350001 6 Soybean, oil-babyfood 0.380000 1.000 1.000 

0600347000 6 Soybean, seed 0.380000 1.000 1.000 

0600349000 6 Soybean, soy milk 0.380000 1.000 1.000 

0600349001 6 Soybean, soy milk-babyfood or in 0.380000 1.000 1.000 

0802148000 8BC Eggplant 0.710000 1.000 1.000 

0802234000 8BC Okra 0.710000 1.000 1.000 

0802270000 8B Pepper, bell 0.710000 1.000 1.000 

0802271000 8B Pepper, bell, dried 0.710000 1.000 1.000 

0802271001 8B Pepper, bell, dried-babyfood 0.710000 1.000 1.000 

0802270001 8B Pepper, bell-babyfood 0.710000 1.000 1.000 

0802272000 8BC Pepper, nonbell 0.710000 1.000 1.000 

0802273000 8BC Pepper, nonbell, dried 0.710000 1.000 1.000 

0802272001 8BC Pepper, nonbell-babyfood 0.710000 1.000 1.000 

0801374000 8A Tomatillo 0.710000 1.000 1.000 

0801375000 8A Tomato 0.710000 1.000 1.000 

0801380000 8A Tomato, Tree 0.710000 1.000 1.000 

0801378000 8A Tomato, dried 0.710000 14.300 1.000 

0801378001 8A Tomato, dried-babyfood 0.710000 14.300 1.000 

0801379000 8A Tomato, juice 0.710000 1.500 1.000 

0801376000 8A Tomato, paste 0.710000 1.000 1.000 

0801376001 8A Tomato, paste-babyfood 0.710000 1.000 1.000 

0801377000 8A Tomato, puree 0.710000 1.000 1.000 

0801377001 8A Tomato, puree-babyfood 0.710000 1.000 1.000 

0801375001 8A Tomato-babyfood 0.710000 1.000 1.000 

0902021000 9B Balsam pear 0.710000 1.000 1.000 

0901075000 9A Cantaloupe 0.710000 1.000 1.000 

0902088000 9B Chayote, fruit 0.710000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.710000 1.000 1.000 
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0902135000 9B Cucumber 0.710000 1.000 1.000 

0901187000 9A Honeydew melon 0.710000 1.000 1.000 

0902308000 9B Pumpkin 0.710000 1.000 1.000 

0902309000 9B Pumpkin, seed 0.710000 1.000 1.000 

0902356000 9B Squash, summer 0.710000 1.000 1.000 

0902356001 9B Squash, summer-babyfood 0.710000 1.000 1.000 

0902357000 9B Squash, winter 0.710000 1.000 1.000 

0902357001 9B Squash, winter-babyfood 0.710000 1.000 1.000 

0901399000 9A Watermelon 0.710000 1.000 1.000 

0901400000 9A Watermelon, juice 0.710000 1.000 1.000 

1001106000 10A Citron 0.280000 1.000 1.000 

1001107000 10A Citrus hybrids 0.280000 1.000 1.000 

1001108000 10A Citrus, oil 0.280000 1.000 1.000 

1003180000 10C Grapefruit 0.280000 1.000 1.000 

1003181000 10C Grapefruit, juice 0.280000 1.000 1.000 

1002197000 10B Kumquat 0.280000 1.000 1.000 

1002199000 10B Lemon 0.280000 1.000 1.000 

1002200000 10B Lemon, juice 0.280000 1.000 1.000 

1002200001 10B Lemon, juice-babyfood 0.280000 1.000 1.000 

1002201000 10B Lemon, peel 0.280000 1.000 1.000 

1002206000 10B Lime 0.280000 1.000 1.000 

1002207000 10B Lime, juice 0.280000 1.000 1.000 

1002207001 10B Lime, juice-babyfood 0.280000 1.000 1.000 

1001240000 10A Orange 0.280000 1.000 1.000 

1001241000 10A Orange, juice 0.280000 1.000 1.000 

1001241001 10A Orange, juice-babyfood 0.280000 1.000 1.000 

1001242000 10A Orange, peel 0.280000 1.000 1.000 

1003307000 10C Pummelo 0.280000 1.000 1.000 

1001369000 10A Tangerine 0.280000 1.000 1.000 

1001370000 10A Tangerine, juice 0.280000 1.000 1.000 

1100009000 11 Apple, dried 0.280000 8.000 1.000 

1100009001 11 Apple, dried-babyfood 0.280000 8.000 1.000 

1100007000 11 Apple, fruit with peel 0.280000 1.000 1.000 

1100010000 11 Apple, juice 0.280000 1.000 1.000 

1100010001 11 Apple, juice-babyfood 0.280000 1.000 1.000 

1100008000 11 Apple, peeled fruit 0.280000 1.000 1.000 

1100008001 11 Apple, peeled fruit-babyfood 0.280000 1.000 1.000 

1100011000 11 Apple, sauce 0.280000 1.000 1.000 

1100011001 11 Apple, sauce-babyfood 0.280000 1.000 1.000 

1100129000 11 Crabapple 0.280000 1.000 1.000 

1100173500 11 Goji berry 0.710000 1.000 1.000 

1100210000 11 Loquat 0.280000 1.000 1.000 

1100266000 11 Pear 0.280000 1.000 1.000 

1100267000 11 Pear, dried 0.280000 6.250 1.000 

1100268000 11 Pear, juice 0.280000 1.000 1.000 

1100268001 11 Pear, juice-babyfood 0.280000 1.000 1.000 

1100266001 11 Pear-babyfood 0.280000 1.000 1.000 

1100310000 11 Quince 0.280000 1.000 1.000 

1202012000 12B Apricot 0.710000 1.000 1.000 

1202013000 12B Apricot, dried 0.710000 6.000 1.000 

1202014000 12B Apricot, juice 0.710000 1.000 1.000 

1202014001 12B Apricot, juice-babyfood 0.710000 1.000 1.000 

1202012001 12B Apricot-babyfood 0.710000 1.000 1.000 

1201090000 12A Cherry 0.710000 1.000 1.000 

1201091000 12A Cherry, juice 0.710000 1.500 1.000 

1201091001 12A Cherry, juice-babyfood 0.710000 1.500 1.000 

1201090001 12A Cherry-babyfood 0.710000 1.000 1.000 

1202230000 12B Nectarine 0.710000 1.000 1.000 

1202260000 12B Peach 0.710000 1.000 1.000 

1202261000 12B Peach, dried 0.710000 7.000 1.000 

1202261001 12B Peach, dried-babyfood 0.710000 7.000 1.000 

1202262000 12B Peach, juice 0.710000 1.000 1.000 
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1202262001 12B Peach, juice-babyfood 0.710000 1.000 1.000 

1202260001 12B Peach-babyfood 0.710000 1.000 1.000 

1203285000 12C Plum 0.710000 1.000 1.000 

1203287000 12C Plum, prune, dried 0.710000 1.000 1.000 

1203287001 12C Plum, prune, dried-babyfood 0.710000 1.000 1.000 

1203286000 12C Plum, prune, fresh 0.710000 1.000 1.000 

1203286001 12C Plum, prune, fresh-babyfood 0.710000 1.000 1.000 

1203288000 12C Plum, prune, juice 0.710000 1.000 1.000 

1203288001 12C Plum, prune, juice-babyfood 0.710000 1.000 1.000 

1203285001 12C Plum-babyfood 0.710000 1.000 1.000 

1301055000 13A Blackberry 0.710000 1.000 1.000 

1301056000 13A Blackberry, juice 0.710000 1.000 1.000 

1301056001 13A Blackberry, juice-babyfood 0.710000 1.000 1.000 

1302057000 13B Blueberry 0.710000 1.000 1.000 

1302057001 13B Blueberry-babyfood 0.710000 1.000 1.000 

1301058000 13A Boysenberry 0.710000 1.000 1.000 

1307130000 13G Cranberry 0.710000 1.000 1.000 

1307131000 13G Cranberry, dried 0.710000 1.000 1.000 

1307132000 13G Cranberry, juice 0.710000 1.100 1.000 

1307132001 13G Cranberry, juice-babyfood 0.710000 1.100 1.000 

1307130001 13G Cranberry-babyfood 0.710000 1.000 1.000 

1302136000 13B Currant 0.710000 1.000 1.000 

1302137000 13B Currant, dried 0.710000 1.000 1.000 

1302149000 13B Elderberry 0.710000 1.000 1.000 

1302174000 13B Gooseberry 0.710000 1.000 1.000 

1304175000 13D Grape 0.710000 1.000 1.000 

1304176000 13D Grape, juice 0.710000 1.000 1.000 

1304176001 13D Grape, juice-babyfood 0.710000 1.000 1.000 

1304179000 13D Grape, wine and sherry 0.710000 1.000 1.000 

1302191000 13B Huckleberry 0.710000 1.000 1.000 

1304195000 13D Kiwifruit, fuzzy 0.710000 1.000 1.000 

1301208000 13A Loganberry 0.710000 1.000 1.000 

1303227000 13C Mulberry 0.710000 1.000 1.000 

1301320000 13A Raspberry 0.710000 1.000 1.000 

1301321000 13A Raspberry, juice 0.710000 1.000 1.000 

1301321001 13A Raspberry, juice-babyfood 0.710000 1.000 1.000 

1301320001 13A Raspberry-babyfood 0.710000 1.000 1.000 

1307359000 13G Strawberry 0.710000 1.000 1.000 

1307360000 13G Strawberry, juice 0.710000 1.000 1.000 

1307360001 13G Strawberry, juice-babyfood 0.710000 1.000 1.000 

1307359001 13G Strawberry-babyfood 0.710000 1.000 1.000 

1400003000 14 Almond 0.710000 1.000 1.000 

1400004000 14 Almond, oil 0.710000 1.000 1.000 

1400004001 14 Almond, oil-babyfood 0.710000 1.000 1.000 

1400003001 14 Almond-babyfood 0.710000 1.000 1.000 

1400059000 14 Brazil nut 0.710000 1.000 1.000 

1400068000 14 Butternut 0.710000 1.000 1.000 

1400081000 14 Cashew 0.710000 1.000 1.000 

1400092000 14 Chestnut 0.710000 1.000 1.000 

1400155000 14 Hazelnut 0.710000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.710000 1.000 1.000 

1400185000 14 Hickory nut 0.710000 1.000 1.000 

1400213000 14 Macadamia nut 0.710000 1.000 1.000 

1400269000 14 Pecan 0.710000 1.000 1.000 

1400278000 14 Pine nut 0.710000 1.000 1.000 

1400282000 14 Pistachio 0.710000 1.000 1.000 

1400391000 14 Walnut 0.710000 1.000 1.000 

1500027000 15 Barley, bran 0.100000 1.000 1.000 

1500026000 15 Barley, flour 0.100000 1.000 1.000 

1500026001 15 Barley, flour-babyfood 0.100000 1.000 1.000 

1500025000 15 Barley, pearled barley 0.100000 1.000 1.000 

1500025001 15 Barley, pearled barley-babyfood 0.100000 1.000 1.000 
Carfentrazone-ethyl (128712) Dietary Exposure and Risk Assessment D428859

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1500065000 15 Buckwheat 0.100000 1.000 1.000 

1500066000 15 Buckwheat, flour 0.100000 1.000 1.000 

1500122000 15 Corn, field, bran 0.100000 1.000 1.000 

1500120000 15 Corn, field, flour 0.100000 1.000 1.000 

1500120001 15 Corn, field, flour-babyfood 0.100000 1.000 1.000 

1500121000 15 Corn, field, meal 0.100000 1.000 1.000 

1500121001 15 Corn, field, meal-babyfood 0.100000 1.000 1.000 

1500125000 15 Corn, field, oil 0.100000 1.000 1.000 

1500125001 15 Corn, field, oil-babyfood 0.100000 1.000 1.000 

1500123000 15 Corn, field, starch 0.100000 1.000 1.000 

1500123001 15 Corn, field, starch-babyfood 0.100000 1.000 1.000 

1500124000 15 Corn, field, syrup 0.100000 1.500 1.000 

1500124001 15 Corn, field, syrup-babyfood 0.100000 1.500 1.000 

1500126000 15 Corn, pop 0.100000 1.000 1.000 

1500127000 15 Corn, sweet 0.100000 1.000 1.000 

1500127001 15 Corn, sweet-babyfood 0.100000 1.000 1.000 

1500226000 15 Millet, grain 0.100000 1.000 1.000 

1500231000 15 Oat, bran 0.100000 1.000 1.000 

1500232000 15 Oat, flour 0.100000 1.000 1.000 

1500232001 15 Oat, flour-babyfood 0.100000 1.000 1.000 

1500233000 15 Oat, groats/rolled oats 0.100000 1.000 1.000 

1500233001 15 Oat, groats/rolled oats-babyfood 0.100000 1.000 1.000 

1500326000 15 Rice, bran 1.300000 1.000 1.000 

1500326001 15 Rice, bran-babyfood 1.300000 1.000 1.000 

1500324000 15 Rice, brown 1.300000 1.000 1.000 

1500324001 15 Rice, brown-babyfood 1.300000 1.000 1.000 

1500325000 15 Rice, flour 1.300000 1.000 1.000 

1500325001 15 Rice, flour-babyfood 1.300000 1.000 1.000 

1500323000 15 Rice, white 1.300000 1.000 1.000 

1500323001 15 Rice, white-babyfood 1.300000 1.000 1.000 

1500329000 15 Rye, flour 0.100000 1.000 1.000 

1500328000 15 Rye, grain 0.100000 1.000 1.000 

1500344000 15 Sorghum, grain 0.250000 1.000 1.000 

1500345000 15 Sorghum, syrup 0.710000 1.000 1.000 

1500381000 15 Triticale, flour 0.100000 1.000 1.000 

1500381001 15 Triticale, flour-babyfood 0.100000 1.000 1.000 

1500404000 15 Wheat, bran 0.100000 1.000 1.000 

1500402000 15 Wheat, flour 0.100000 1.000 1.000 

1500402001 15 Wheat, flour-babyfood 0.100000 1.000 1.000 

1500403000 15 Wheat, germ 0.100000 1.000 1.000 

1500401000 15 Wheat, grain 0.100000 1.000 1.000 

1500401001 15 Wheat, grain-babyfood 0.100000 1.000 1.000 

1500405000 15 Wild rice 0.100000 1.000 1.000 

1800002000 18 Alfalfa, seed 15.000000 1.000 1.000 

1901029000 19A Basil, dried leaves 10.380000 1.000 1.000 

1901029001 19A Basil, dried leaves-babyfood 10.380000 1.000 1.000 

1901028000 19A Basil, fresh leaves 10.380000 1.000 1.000 

1901028001 19A Basil, fresh leaves-babyfood 10.380000 1.000 1.000 

1901102500 19A Chive, dried leaves 10.380000 1.000 1.000 

1901118000 19A Cilantro, leaves 10.380000 1.000 1.000 

1901118001 19A Cilantro, leaves-babyfood 10.380000 1.000 1.000 

1902105000 19B Cinnamon 10.380000 1.000 1.000 

1902105001 19B Cinnamon-babyfood 10.380000 1.000 1.000 

1902119000 19B Coriander, seed 10.380000 1.000 1.000 

1902119001 19B Coriander, seed-babyfood 10.380000 1.000 1.000 

1902143000 19B Dill, seed 10.380000 1.000 1.000 

1901144000 19A Dillweed 10.380000 1.000 1.000 

1901184000 19A Herbs, other 10.380000 1.000 1.000 

1901184001 19A Herbs, other-babyfood 10.380000 1.000 1.000 

1901202000 19A Lemongrass 10.380000 1.000 1.000 

1901220000 19A Marjoram 10.380000 1.000 1.000 

1901220001 19A Marjoram-babyfood 10.380000 1.000 1.000 
Carfentrazone-ethyl (128712) Dietary Exposure and Risk Assessment D428859

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1901249000 19A Parsley, dried leaves 10.380000 1.000 1.000 

1901249001 19A Parsley, dried leaves-babyfood 10.380000 1.000 1.000 

1902274000 19B Pepper, black and white 10.380000 1.000 1.000 

1902274001 19B Pepper, black and white-babyfood 10.380000 1.000 1.000 

1901334000 19A Savory 10.380000 1.000 1.000 

1902354000 19B Spices, other 10.380000 1.000 1.000 

1902354001 19B Spices, other-babyfood 10.380000 1.000 1.000 

2003114001 20C Coconut, oil-babyfood 0.710000 1.000 1.000 

2003128000 20C Cottonseed, oil 1.000000 1.000 1.000 

2003128001 20C Cottonseed, oil-babyfood 1.000000 1.000 1.000 

2001163000 20A Flax seed, oil 0.710000 1.000 1.000 

2001319000 20A Rapeseed, oil 0.710000 1.000 1.000 

2001319001 20A Rapeseed, oil-babyfood 0.710000 1.000 1.000 

2002330000 20B Safflower, oil 0.710000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.710000 1.000 1.000 

2001337000 20A Sesame, oil 0.710000 1.000 1.000 

2001337001 20A Sesame, oil-babyfood 0.710000 1.000 1.000 

2001336000 20A Sesame, seed 0.710000 1.000 1.000 

2001336001 20A Sesame, seed-babyfood 0.710000 1.000 1.000 

2002365000 20B Sunflower, oil 0.710000 1.000 1.000 

2002365001 20B Sunflower, oil-babyfood 0.710000 1.000 1.000 

2002364000 20B Sunflower, seed 0.710000 1.000 1.000 

3100047000 31 Beef, fat 0.100000 1.000 1.000 

3100047001 31 Beef, fat-babyfood 0.100000 1.000 1.000 

3100048000 31 Beef, kidney 0.100000 1.000 1.000 

3100049000 31 Beef, liver 0.100000 1.000 1.000 

3100049001 31 Beef, liver-babyfood 0.100000 1.000 1.000 

3100044000 31 Beef, meat 0.100000 1.000 1.000 

3100046000 31 Beef, meat byproducts 0.100000 1.000 1.000 

3100046001 31 Beef, meat byproducts-babyfood 0.100000 1.000 1.000 

3100045000 31 Beef, meat, dried 0.100000 1.920 1.000 

3100044001 31 Beef, meat-babyfood 0.100000 1.000 1.000 

3200171000 32 Goat, fat 0.100000 1.000 1.000 

3200172000 32 Goat, kidney 0.100000 1.000 1.000 

3200173000 32 Goat, liver 0.100000 1.000 1.000 

3200169000 32 Goat, meat 0.100000 1.000 1.000 

3200170000 32 Goat, meat byproducts 0.100000 1.000 1.000 

3300189000 33 Horse, meat 0.100000 1.000 1.000 

3400293000 34 Pork, fat 0.100000 1.000 1.000 

3400293001 34 Pork, fat-babyfood 0.100000 1.000 1.000 

3400294000 34 Pork, kidney 0.100000 1.000 1.000 

3400295000 34 Pork, liver 0.100000 1.000 1.000 

3400290000 34 Pork, meat 0.100000 1.000 1.000 

3400292000 34 Pork, meat byproducts 0.100000 1.000 1.000 

3400292001 34 Pork, meat byproducts-babyfood 0.100000 1.000 1.000 

3400290001 34 Pork, meat-babyfood 0.100000 1.000 1.000 

3400291000 34 Pork, skin 0.100000 1.000 1.000 

3500341000 35 Sheep, fat 0.100000 1.000 1.000 

3500341001 35 Sheep, fat-babyfood 0.100000 1.000 1.000 

3500342000 35 Sheep, kidney 0.100000 1.000 1.000 

3500343000 35 Sheep, liver 0.100000 1.000 1.000 

3500339000 35 Sheep, meat 0.100000 1.000 1.000 

3500340000 35 Sheep, meat byproducts 0.100000 1.000 1.000 

3500339001 35 Sheep, meat-babyfood 0.100000 1.000 1.000 

3600222000 36 Milk, fat 0.050000 1.000 1.000 

3600222001 36 Milk, fat-baby food/infant formu 0.050000 1.000 1.000 

3600223000 36 Milk, nonfat solids 0.050000 1.000 1.000 

3600223001 36 Milk, nonfat solids-baby food/in 0.050000 1.000 1.000 

3600225001 36 Milk, sugar (lactose)-baby food/ 0.050000 1.000 1.000 

3600224000 36 Milk, water 0.050000 1.000 1.000 

3600224001 36 Milk, water-babyfood/infant form 0.050000 1.000 1.000 

3800221000 38 Meat, game 0.100000 1.000 1.000 
Carfentrazone-ethyl (128712) Dietary Exposure and Risk Assessment D428859

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3900312000 39 Rabbit, meat 0.100000 1.000 1.000 

4000094000 40 Chicken, liver 0.100000 1.000 1.000 

4000095000 40 Chicken, meat byproducts 0.100000 1.000 1.000 

4000095001 40 Chicken, meat byproducts-babyfoo 0.100000 1.000 1.000 

5000383000 50 Turkey, liver 0.100000 1.000 1.000 

5000383001 50 Turkey, liver-babyfood 0.100000 1.000 1.000 

5000384000 50 Turkey, meat byproducts 0.100000 1.000 1.000 

5000384001 50 Turkey, meat byproducts-babyfood 0.100000 1.000 1.000 

6000302000 60 Poultry, other, liver 0.100000 1.000 1.000 

6000303000 60 Poultry, other, meat byproducts 0.100000 1.000 1.000 

8000157000 80 Fish-freshwater finfish 0.300000 1.000 1.000 

8000158000 80 Fish-freshwater finfish, farm ra 0.300000 1.000 1.000 

8000160000 80 Fish-saltwater finfish, other 0.300000 1.000 1.000 

8000159000 80 Fish-saltwater finfish, tuna 0.300000 1.000 1.000 

8000161000 80 Fish-shellfish, crustacean 0.300000 1.000 1.000 

8000162000 80 Fish-shellfish, mollusc 0.300000 1.000 1.000 

8601000000 86A Water, direct, all sources 0.086000 1.000 1.000 

8602000000 86B Water, indirect, all sources 0.086000 1.000 1.000