Evidence Table 3:   Methodologic quality of literature on treatment of coexisting cataract and glaucoma.

				Quality Score

			%	%	%	%	%	%

Advanced Glaucoma Intervention Study, The (AGIS):, 1998

United States

	RCT	Less than maximal medical therapy for glaucoma;	88	50	58	55	100	70

Anand, Menage, Bailey, 1997

Europe

	Cohort	None stated	25	0	0	50	67	28

Anders, Pham, Holschbach et al., 1997

Europe

	RCT	IOP <21 mmHg	19	50	83	83	100	67

Arnold, 1996

United States

	Cohort	None stated	75	0	50	58	0	37

Bellucci, Perfetti, Babighian et al., 1997

Europe

	Cohort	None stated	13	0	33	25	33	21

Bellucci, Luraschi, 1998

Europe

	NRCT	None stated	19	33	17	17	33	24

Berestka, Brown, 1997

United States

	Cohort	Followup < 6 months	63	0	67	58	50	48

Blondeau, Phelps, 1981 

United States

	RCT	Previous cataract surgery; Inflammatory glaucoma; Neovascular glaucoma;

Ocular injury;

Other ocular surgery	88	67	58	63	100	75

Bobrow, 1998 

United States

	RCT	Previous cataract surgery; Asymmetric glaucoma	75	67	83	83	100	82

Borggrefe, Lieb, Grehn, 1999

Europe

	RCT	Other intraocular surgery except LTP	88	50	67	42	75	64

Budenz, Pyfer, Singh et al., 1999

United States

	Cohort	Previous cataract surgery	63	17	33	75	100	58

Caprioli, Park, Weitzman, 1996

United States

	Cohort	Inflammatory glaucoma; Neovascular glaucoma;

Angle closure glaucoma	88	50	100	75	100	83

Carlson, Alward, Barad et al., 1997

United States

	RCT	Previous cataract surgery; Coexisting ocular disease	88	50	100	58	100	79

Chia, Goldberg, 1998

Australia

	Cohort	None stated	83	0	58	33	75	50

Cohen, 1990 

United States

	Cohort	If IOP controlled by less than maximal therapy	63	33	92	17	100	61

Cohen, Greff, Novack et al., 1996

United States

	RCT	Previous glaucoma laser surgery;

Inflammatory glaucoma;

Neovascular glaucoma;

History of incisional surgery	88	83	92	33	80	69

Collaborative Normal-Tension Glaucoma Study Group, 1998a

United States

	RCT	Age < 20;

Inflammatory glaucoma;

Neovascular glaucoma;

Narrow angle	75	33	50	75	100	67

Collaborative Normal-Tension Glaucoma Study Group, 1998b

United States

	RCT	Age < 20;

Inflammatory glaucoma;

Neovascular glaucoma;

Narrow angle	75	33	50	75	100	67

Crestani, De Natale, Steindler, 1997

Europe

	Cohort	None stated	13	0	0	0	0	3

Dastur, 1994

India

	NRCT	Unilateral glaucoma or advanced visual field changes;

Low tension glaucoma;

Prior topical therapies for glaucoma; 

Diabetes	75	0	75	69	0	44

Demailly, Kretz, 1992

Europe

	RCT	None stated	50	33	42	0	50	35

Derick, Evans, Baker, 1998

United States

	Cohort	None stated	88	0	100	58	67	63

El-Sayyad, Helal, El-Maghraby et al., 1999

Saudi Arabia

	RCT	Corneal opacities;

Posterior segment disorder;

Cataracts too dense for phacoemulsification	88	67	33	67	50	61

Gandolfi, Vecchi, 1997

Europe

	RCT	Previous cataract surgery	25	50	100	67	67	62

Gayton, Van der Karr, Sanders, 1996

United States

	Cohort	None stated	38	0	50	33	33	31

Gayton, Van der Karr, Sanders, 1999

United States

	RCT	None stated	44	33	92	50	33	50

Gianoli, Schnyder, Bovey et al., 1999

Europe

	RCT	Previous glaucoma surgery;

Inflammatory glaucoma;

Neovascular glaucoma;

Secondary glaucoma	63	50	100	33	50	59

Gimbel, Meyer, DeBroff et al., 1995

Canada

	RCT	Neovascular glaucoma;

Previous intraocular surgery;

Advanced glaucoma;

IOP > 27, or proliferative diabetic retinopathy	75	33	92	67	50	63

Hayashi, Hayashi, Nakao et al., 2000

Japan

	Cohort	Ocular Hypertension;

Secondary glaucoma	86	33	33	50	50	50

Hennis, Stewart, 1991 

United States

	RCT	None stated	75	33	75	50	17	50

Honjo, Tanihara, Negi et al., 1996

Japan

	Cohort	None stated	0	0	17	33	17	13

Hugkulstone, Sadiq, Rubasingham, 1997 

Europe

	RCT	None stated	31	67	17	67	100	56

Hurvitz, 1993

United States

	Cohort	Previous glaucoma surgery;

Chronic angle closure glaucoma;

Uveitic glaucoma	50	0	33	50	33	33

Kendrick, Kollarits, Khan, 1996

United States

	Cohort	None stated	19	0	17	33	33	20

Kim, Jung, Hwang, 1998 

Korea

	RCT	Previous cataract surgery;

Inflammatory glaucoma;

Neovascular glaucoma;

Congenital or secondary glaucoma;

Any past eye surgery 	63	17	67	50	33	46

Kitazawa, Suemori-Matsushita, Yamamoto et al., 1993

Japan

	RCT	Previous intraocular surgery;

Asymmetric ocular conditions	63	50	100	50	100	73

Kosmin, Wishart, Ridges, 1997

Europe

	Cohort	None stated	94	33	33	67	75	60

Kosmin, Wishart, Ridges, 1998

Europe

	Cohort	None stated	31	17	100	33	67	50

Krupin, Feitl, Bishop, 1989

United States

	RCT	Previous cataract surgery;

Inflammatory glaucoma;

Neovascular glaucoma;

Narrow angle	63	17	50	75	67	54

Lemon, Shin, Kim et al., 1998

United States

	RCT	Secondary glaucoma;

Previous ocular incisional surgery	63	50	92	75	50	66

Lewis, Phelps, 1984

United States

	RCT	Previous glaucoma laser surgery;

Previous cataract surgery;

Inflammatory glaucoma;

Neovascular glaucoma;

Ocular injury (not open angle);

Other ocular surgery.	88	67	58	69	100	76

Liu. Su, Chou et al., 2000

Taiwan

	Cohort	Previous intraocular surgery;

Incomplete followup;

Intraoperative vitreous loss	75	17	92	58	75	63

Lyle, Jin, 1991 

United States

	Cohort	Inadequate followup	81	33	83	21	100	64

Manoj, Chako, Khan, 2000

Europe

	Cohort	Previous trabeculectomy with antimetabolites or other non- trabeculectomy filtering surgery;

Secondary glaucoma or angle closure glaucoma;

Intraoperative complications; Followed < 6 months	63	0	14	57	33	33

McGuigan, Gottsch, Stark et al., 1986 

United States

	Cohort	Incomplete followup	38	0	92	43	25	40

McKinzie, Boggs, 1989

United States

	Cohort	Cataract extraction by phacoemulsification	6	0	83	60	0	30

Murchison, Shields, 1989

United States

	Cohort	None stated	69	0	100	50	0	44

Murchison, Shields, 1990

United States

	Cohort	None stated	50	33	100	50	100	67

Naveh, Kottass, Glovinsky et al., 1990 

Israel

	Cohort	Previous glaucoma surgery	88	0	33	50	67	48

Neumann, Zalish, Oliver, 1988 

Israel

	Cohort	Inflammatory glaucoma;

High myopia;

Advanced proliferative diabetic retinopathy; 

Uveitis	63	0	33	43	33	34

Nielsen, 1997 

Europe

	NRCT	None stated	33	0	17	43	50	29

O'Grady, Juzych, Shin et al., 1993 

United States

	RCT	None stated	31	50	83	29	33	45

Park, Weitzman, Caprioli, 1997

United States

	Cohort	Previous cataract surgery;

Inflammatory glaucoma;

Neovascular glaucoma;

Acute ACG	63	17	100	50	83	63

Robin, 1993 

United States

	RCT	Previous glaucoma laser surgery;

Inflammatory glaucoma;

Neovascular glaucoma	75	83	67	57	100	67

Robin, Ramakrishnan, Krishnadas et al., 1997 

India

	RCT	Neovascular glaucoma;

Prior intraocular surgery;

Chronic uveitis; 

VA <10/200	75	67	100	50	100	78

Rossetti, Bucci, Miglior et al., 1997 

Europe

	RCT	None stated	19	17	0	0	17	11

Sanders, Cantor, Dobler et al., 1999

United States

	RCT	Age < 21;

Inflammatory glaucoma;

Neovascular glaucoma;

Pregnancy	88	83	100	71	100	88

Savage, Thomas, Belcher et al., 1985

United States

	Cohort	Age < 50;

Trauma;

Diabetes;

Known ocular pathology besides glaucoma	81	0	33	14	17	29

Shin, Kim, Sheth et al., 1998 

United States

	RCT	None stated	38	33	58	71	67	53

Shin, Ren, Juzych et al., 1998

United States

	RCT	Previous cataract surgery;

Glaucoma other than open angle	63	83	100	71	75	78

Shin, Kim, Ren et al., 1998

United States

	RCT	Previous glaucoma laser surgery;

Previous ocular incisional surgery	75	50	92	71	100	78

Shingleton, Jacobson, Kuperwaser, 1995

United States

	Cohort	Inflammatory glaucoma;

Neovascular glaucoma;

Mature or densely brunescent cataracts;

Low tension glaucoma;

Angle closure glaucoma	44	0	100	36	50	46

Shingleton, Chaudhry, O’Donoghue 

et al., 1999

United States

	NRCT	None stated	38	33	100	60	83	63

Shingleton, Gamell, O’Donoghue et al., 1999 

United States

	Cohort	None stated	69	0	92	57	75	59

Spaeth, 1980

United States

	RCT	None stated	19	17	42	30	0	22

Stewart, Crinkley, Carlson, 1994b

United States

	Cohort	Neovascular glaucoma;

Angle closure glaucoma;

Congenital glaucoma	19	17	42	50	50	36

Storr-Paulsen, Pedersen, Laugensen, 1998

Europe

	RCT	Previous cataract surgery;

Inflammation;

Corneal dystrophy;

Diabetes;

Systemic steroids or beta blockers	75	50	92	43	100	72

Tezel, Kolker, Kass et al., 1997a

United States

	Cohort	None stated	38	33	50	29	50	40

Tezel, Kolker, Kass et al., 1997b

United States

	Cohort	Eyes with intraoperative complications	38	50	42	29	83	48

Tuulonen, Niva, Alanko, 1987 

Europe

	NRCT	Previous cataract surgery;

Inflammatory glaucoma;

Neovascular glaucoma	50	33	33	65	100	56

Vu, Shields, 1988 

United States

	NRCT	Other intraocular surgery	38	0	83	57	0	36

Vyas, Bacon, Percival, 1998

Europe

	NRCT	None stated	50	0	58	29	33	34

Wand, 1996

United States

	Cohort	None stated	63	17	92	14	100	57

Wedrich, Menapace, Hirsch et al., 1996

Europe

	Cohort	None stated	25	33	50	57	50	43

West, Burke, Cunliffe et al., 1992

Europe

	RCT	Previous cataract surgery	44	83	83	60	75	69

Wilson, 1989

St. Lucia

	RCT	None stated	63	50	100	55	100	74

Wishart, Austin, 1993

Europe

	Cohort	Less than maximal medical treatment for glaucoma	63	33	92	33	50	54

Wong, Ruderman, Krupin et al., 1994 

United States

	RCT	Previous glaucoma laser surgery;

Previous intraocular surgery;

Intraocular inflammation or corneal disease	75	67	58	43	67	62

Wyse, Meyer, Ruderman et al., 1998 

United States

	RCT	Previous cataract surgery;

Inflammatory glaucoma;

Neovascular glaucoma	75	50	92	50	33	60

Yalvac, Airaksinen, Tuulonen, 1997

Europe

	Cohort	Previous cataract surgery;

Inflammatory glaucoma;

Neovascular glaucoma;

Patients using topical steroids	63	0	58	43	67	46

Yu, Chong, Caesar et al., 1996

Europe

	Cohort	Age < 60;

Previous ocular surgery;

Use of ocular hypertensives;

Normal tension glaucoma	88	17	83	36	100	65