### Dec ember 2010 ATSDR Minimal Risk Levels Page 1 of 14 

## A gency for T oxic S ubstances and D isease R egistry 

# MINIMAL RISK LEVELS (MRLs) **Dec e**  **mber 20 10** 

**Dura -**  **Uncertainty Cover CAS**  **Name Route tion MRL Factors Endpoint Status**  **Date Number** 

**______________________________________________________________________________________________________________ ACENAPHTHENE Oral Int. 0.6 mg/kg/day 300 Hepat**  **ic Final 08/95 83**  **- 32**  **- 9**  **ACETONE Inh. Acute 26 ppm 9 Neurol. Final 05/94 67**  **- 64**  **- 1**  **Int. 13 ppm 100 Neurol. Chr. 13 ppm 100 Neurol.**  **Oral Int. 2 mg/kg/day 100 Hemato. ACROLEIN Inh. Acute 0.003 ppm 100 Resp. Final 08/07**  **107 -**  **02 -**  **8 Int. 0.00004 ppm 300 Resp.**  **Oral Int. 0.004 mg/kg/day 100 Gastro. ACRYLAMIDE Oral Acute 0.02 mg/kg/day 100 Repro. Draft 09/09**  **79 -**  **06 -**  **1 Int. 0.002 mg/kg/day 100 Neurol.**  **ACRYLONITRILE Inh. Acute 0.1 ppm 10 Neurol. Final 12/90 107**  **- 13**  **- 1**  **Oral Acute 0.1 mg/kg/day 100 Develop.**  **Int. 0.01 mg/kg/day 1000 Repro. Chr. 0.04 mg/kg/day 100 Hemato.** 

**ALDRIN Oral Acute 0.002 mg/kg/day 1000 Develop. Final 09/02**  **309 -**  **00 -**  **2 Chr. 0.00003 mg/kg/day 1000 Hepatic**  **ALUMINUM Oral Int. 1.0 mg/kg/day 30 Neurol. Final 09/08 7429**  **- 90**  **- 5**  **Chr. 1.0 mg/kg/day 90 Neurol. AMERICIUM Rad. Acute 4 mSv 3 Develop. Final 10/04**  **7440 -**  **35 -**  **9 Chr. 1 mSv/yr**  **3 Other AMMONIA Inh. Acute 1.7 ppm 30 Resp. Final 10/04**  **7664 -**  **41 -**  **7 Chr. 0.1 ppm 30 Resp.** 

**ANTHRACENE Ora l Int. 10 mg/kg/day 100 Hepatic Final 08/95**  **120 -**  **12 -**  **7**

### Dec ember 2010 ATSDR Minimal Risk Levels Page 2 of 14 **ARSENIC Oral Acute 0.005 mg/kg/day 10 Gastro. Final 08/07 7440**  **- 38**  **- 2**  **Chr. 0.0003 mg/kg/day 3 Dermal**  **ATRAZINE Oral Acute 0.01 mg/kg/day 100 Body Wt. Final 09/03 1912**  **- 24**  **- 9**  **Int. 0.003 mg/kg/day 300 Repro. BARIUM, SOLUBLE SALTS Oral Int. 0.**  **2 mg/kg/day 100 Renal Final 08/07 7440**  **- 39**  **- 3**  **Chr. 0.2 mg/kg/day 100 Renal BENZENE Inh. Acute 0.009 ppm 300 Immuno. Final 08/07**  **71 -**  **43 -**  **2 Int. 0.006 ppm 300 Immuno.**  **Chr. 0.003 ppm 10 Immuno. Oral Chr. 0.0005 mg/kg/day 30 Immuno.**  **BERYLLIUM Oral Chr. 0.002 mg/kg/day 300 Gastro. Final 09/02 7440**  **- 41**  **- 7**  **BIS(2 -**  **CHLOROETHYL) ETHER Inh. Int. 0.02 ppm 1000 Body Wt. Final 12/89 111**  **- 44**  **- 4**  **BIS(CHLOROMETHYL) ETHER Inh. Int. 0.0003 ppm 100 Resp. Final 12/89**  **542 -**  **88 -**  **1**

**BORON Inh. Acute 0. 3**  **mg/m3 3 Resp.**  **Final 11/10 7440**  **- 42**  **- 8**  **Oral Acute 0.2 mg/kg/day 100 Develop.**  **Int. 0.2 mg/kg/day 66 Develop. BROMODICHLOROMETHANE Oral Acute 0.04 mg/kg/day 1000 Hepatic Final 12/89**  **75 -**  **27 -**  **4 Chr. 0.02 mg/kg/day 1000 Renal**  **BROMOFORM Oral Acute 0.7 mg/kg/day 100 Hepatic Final 09/05 75**  **- 25**  **- 2**  **Int. 0.2 mg/kg/day 300 Hepatic**  **Chr. 0.02 mg/kg/day 3000 Hepatic BROMOMETHANE Inh. Acute 0.05 ppm 100 Neurol. Final 09/92**  **74 -**  **83 -**  **9 Int. 0.05 ppm 100 Neurol.**  **Chr. 0.005 ppm 100 Neurol. Oral Int. 0.003 mg/kg/day 100 Gastro.**  **1,3 -**  **BUTADIENE Inh. Acute**  **0.1 ppm 90 Dev elop. Draft 09/09**  **106 -**  **99 -**  **0**

**2 -**  **BUTOXYETHANOL Inh. Acute 6 ppm 9 Hemato. Final 10/98 111**  **- 76**  **- 2** 

**( ETHYLENE GLYCOL MONOBUTYL ETHER**  **) Int. 3 ppm 9**  **Hemato. Chr. 0.2 ppm 3 Hemato.**  **Oral Acute 0.4 mg/kg/day 90 Hemato. Int. 0.07 mg/kg/day 1000 Hepatic** 

### Dec ember 2010 ATSDR Minimal Risk Levels Page 3 of 14 **CADMIUM Inh. Acute 0.00003 mg/m3 300 Resp. Draft 09/08 7440**  **- 43**  **- 9**  **Chr. 0.00001 mg/m3 9 Renal Oral Int. 0.0005 mg/kg/**  **day 100 Musculo. Chr. 0.0001 mg/kg/day 3 Renal**  **CARBON DISULFIDE Inh. Chr. 0.3 ppm 30 Neurol. Final 08/96 75**  **- 15**  **- 0**  **Oral Acute 0.01 mg/kg/day 300 Hepatic**  **CARBON TETRACHLORIDE Inh. Int. 0.03 ppm 30 Hepatic Final 09/05 56**  **- 23**  **- 5**  **Chr. 0.03 ppm 30 Hepatic Oral Acute 0.02 mg/kg/day 300 Hepatic**  **Int. 0.007 mg/kg/day 100 Hepatic CESIUM Rad. Acute 4 mSv 3 Develop. Final 10/04**  **7440 -**  **46 -**  **2 Chr. 1 mSv/yr 3 Other**  **CHLORDANE Inh. Int. 0.0002 mg/m3 100 Hepatic Final 05/94 57**  **- 74**  **- 9**  **Chr. 0.00 002 mg/m3 1000 Hepatic**  **Oral Acute 0.001 mg/kg/day 1000 Develop. Int. 0.0006 mg/kg/day 100 Hepatic**  **Chr. 0.0006 mg/ kg/day 100 Hepatic**  **CHLORDECONE Oral Acute 0.01 mg/kg/day 100 Neurol. Final 08/95 143**  **- 50**  **- 0**  **Int. 0.0005 mg/kg/day 100 Renal Chr. 0.0005 mg/kg/day 100 Renal**  **CHLORFENVINPHOS Oral Acute 0.002 mg/kg/day 1000 Neurol. Final 09/97 470**  **- 90**  **- 6**  **Int. 0.002 mg/kg/da y 1000 Immuno.**  **Chr. 0.0007 mg/kg/day 1000 Neurol.**

**CHLORINE Inh. Acute 0.0 6**  **ppm 3 Resp. Final 11/10**  **7782 -**  **50 -**  **5 Int. 0.002 ppm 90 Resp.**  **Chr. 0.00005 ppm 30 Resp. CHLORINE DIOXIDE Inh. Int. 0.001 ppm 300 Resp. Final 10/04**  **10049 -**  **04 -**  **4**

**CHLORITE Oral Int. 0.1 mg/kg/day 30 Neurol. Final 10/04**  **7758 -**  **19 -**  **2 CHLOROBENZENE Oral Int. 0.4 mg/kg/day 100 Hepatic Final 12/90**  **108 -**  **90 -**  **7**

**CHLORODIBROMOMETHANE Oral Acute 0.1 mg/kg/day 300 Hepatic Final 09/05**  **124 -**  **48 -**  **1 Chr. 0.09 mg/kg/day 300 Hepatic**  **CHLOROETHANE Inh. Acute 15 ppm 100 Develop. Final 12/98 75**  **- 00**  **- 3** 

### Dec ember 2010 ATSDR Minimal Risk Levels Page 4 of 14 **CHLOROFORM Inh. Acute 0.1 ppm 30 Hepatic Final 09/97 67**  **- 66**  **- 3**  **Int. 0.05 ppm 300 Hepatic Chr. 0.02 ppm**  **100 Hepatic Oral Acute 0.3 mg/kg/day 100 Hepatic**  **Int. 0.1 mg/kg/day 100 Hepatic Chr.**  **0.01 mg/kg/day 1000 Hepatic CHLOROMETHANE Inh. Acute 0.5 ppm 100 Neurol. Final 12/98**  **74 -**  **87 -**  **3 Int. 0.2 ppm 300 Hepatic**  **Chr. 0.05 ppm 1000 Neurol.**

**4 -**  **CHLOROPHENOL Oral Acute 0.01 mg/kg/day 100 Hepatic Final 07/99 106**  **- 48**  **- 9**  **CHLORPYRIFOS Oral Acute 0.003 mg/kg/day 10 Neurol. Final 09/97**  **2921 -**  **88 -**  **2 Int. 0.003 mg/kg/day 10 Neurol.**  **Chr. 0.001 mg/kg/day 100 Neurol. CHROMIUM(III) SOLUBLE PARTICULATES Inh. Int. 0.0001 mg/m3**  **300 Resp. Draft 09/08 16065**  **- 83**  **- 1**  **CHROMIUM(III) INSOL .**  **PART ICULATE**  **S Inh. Int. 0.005 mg/m3 90 Resp. Draft 09/08**  **16065 -**  **83 -**  **1 CHROMIUM(VI) Oral Int. 0.005 mg/kg/day 100**  **H emato. Draft 09**  **/08 18540**  **- 29**  **- 9**  **Chr. 0.001 mg/kg/day 100 G**  **astro. CHROMIUM(VI), AEROSOL MISTS Inh. Int. 0.000005 mg/m3 100 Resp. Draft 09/08**  **18540 -**  **29 -**  **9 Chr. 0.000005 mg/m3 100 Resp.**  **CHROMIUM(VI), PARTICULATES Inh. Int. 0.0003 mg/m3 30 Resp. Draft 09/08 18540**  **- 29**  **- 9**  **COBALT Inh. Chr. 0.0001 mg/m3 10 Resp. Final 10/04 7440**  **- 48**  **- 4**  **Oral Int. 0.01 mg/kg/day 100 Hemato. Rad. Acute 4 mSv 3 Develop.**  **Chr. 1 mSv/yr 3 Othe r**  **COPPER Oral Acute 0.01 mg/kg/day 3 Gastro. Final 10/04 7440**  **- 50**  **- 8**  **Int. 0.01 mg/kg/day 3 Gastro. CRESOLS Oral Int. 0.1 mg/kg**  **/day 100 Resp. Final 09/08 1319**  **- 77**  **- 3**  **Chr. 0.1 mg/kg/day 1000 Resp. CYANIDE, SODIUM Oral Int. 0.05 mg/kg/day 100 Repro. Final 07/06**  **143 -**  **33 -**  **9**

### Dec ember 2010 ATSDR Minimal Risk Levels Page 5 of 14 **CYHALOTHR IN Oral Acute 0.01 mg/kg/day 100 Gastro. Final 09/03**  **68085 -**  **85 -**  **8 Int. 0.01 mg/kg/day 100 Gastro.**  **CYPERMETHRIN Oral Acute 0.02 mg/kg/day 100 Neurol. Final 09/03**  **52315 -**  **07 -**  **8**

**DDT, P,P' -**  **Oral Acute 0.0005 mg/kg/day 1000 Develop. Final 09/02 50**  **- 29**  **- 3**  **Int. 0.0005 mg/kg/day 100 Hepatic**

**DIAZINON Inh. Int. 0.01 mg/m3 30 Neurol. Final 09/08**  **333 -**  **41 -**  **5 Oral Acute 0.006 mg/kg/day 100 Neurol.**  **Int. 0.002 mg/kg/day 100 Neurol .**  **Chr. 0.0007 mg/kg/day 100 Neurol. 1,2**  **- DIBROMO**  **- 3**  **- CHLOROPROPANE Inh. Int. 0.0002 ppm 100 Repro. Final 09/92**  **96 -**  **12 -**  **8 Oral Int**  **. 0.002 mg/kg/day 1000 Repro.**

**DI -**  **N -**  **BUTYL PHTHALATE Oral Acute 0.5 mg/kg/day 100 Develop. Final 09/01 84**  **- 74**  **- 2**  **1,2 -**  **DICHLOROBENZENE Oral Acute 0.7 mg/kg/day 100 Hepatic Final 07/06**  **95 -**  **50 -**  **1 Int. 0.6 mg/kg/day 100 Hepatic**  **Chr. 0.3 mg/kg/day 100 Renal 1,3**  **- DICHLOROBENZENE**  **Oral Acute 0.4 mg/kg/day 100 Hepatic F inal 07/06**  **541 -**  **73 -**  **1 Int. 0.02 mg/kg/day 100 Endocr.**  **1,4 -**  **DICHLOROBENZENE Inh. Acute 2 ppm 10 Ocular Final 07/06**  **106 -**  **46 -**  **7 Int. 0.2 ppm 100 Hepatic**  **Chr. 0.01 ppm 30 Resp. Oral Int. 0.07 mg/kg/day 100 Hepatic**  **Chr. 0.07 mg/kg/day 100 Hepatic 1,2**  **- DICHLOROETHANE Inh. Chr. 0.6 ppm 90 Hepatic Final 09/01**  **107 -**  **06 -**  **2 Oral Int. 0.2 mg/kg/day 300 Renal**  **1,1 -**  **DICHLOROETHENE Inh. Int. 0.02 ppm 100 Hepatic Final 05/94**  **75 -**  **35 -**  **4 Oral Chr. 0.009 mg/kg/day 1000 Hepatic** 

**1,2 -**  **DICHLOROETHENE, CIS -**  **Oral Acute 1 mg/kg/day 100 Hemato . Final 08/96**  **156 -**  **59 -**  **2 Int. 0.3 mg/kg/day 100 Hemato.**  **1,2 -**  **DICHLOROETHENE, TRANS -**  **Inh. Acute 0.2 ppm 1000 Hepatic Final 08/96 156**  **- 60**  **- 5**  **Int. 0.2 ppm 1000 Hepatic Oral Int. 0.2 mg/kg/day 100 Hepatic** 

### Dec ember 2010 ATSDR Minimal Risk Levels Page 6 of 14 **2,4 -**  **DICHLOROPHENOL Oral Int. 0.003 mg/kg/day 100 Immuno. Final 07/99 120**  **- 83**  **- 2**  **1,2 -**  **DICH LOROPROPANE Inh. Acute 0.05 ppm 1000 Resp. Final 12/89**  **78 -**  **87 -**  **5 Int. 0.007 ppm 1000 Resp.**  **Oral Acute 0.1 mg/kg/day 100 0 Neurol.**  **Int. 0.07 mg/kg/day 1000 Hemato. Chr. 0.09 mg/kg/day 1000 Hepatic** 

**1,3 -**  **DICHLOROPROPENE Inh. Int. 0.008 ppm 30 Res p. Final 09/08**  **542 -**  **75 -**  **6 Chr. 0.007 ppm 30 Resp.**  **Oral Int. 0.04 mg/kg/day 100 Gastro. Chr. 0.03 mg/kg**  **/day 100 Gastro. 2,3**  **- DICHLOROPROPENE Inh. Acute 0.002 ppm 90 Resp. Final 09/08**  **78 -**  **88 -**  **6 DICHLORVOS Inh. Acute 0.002 ppm 100 Neurol. Final 09/97**  **62 -**  **73 -**  **7 Int. 0.0003 ppm 100 Neurol.**  **Chr. 0.00006 ppm 100 Neurol. Oral Acute 0.004 mg/kg/day 1000 Neurol.**  **Int. 0.003 mg/kg/day 10 Neurol. Chr. 0.0005 mg/kg/day 100 Neurol.**  **DIELDRIN Oral Int. 0.0001 mg/kg/day 100 Neurol. Final 09 /02**  **60 -**  **57 -**  **1 Chr. 0.00005 mg/kg/day 100 Hepatic** 

**DI(2 -**  **ETHYLHEXYL)PHTHALATE Oral Int. 0.1 mg/kg/day 100 Repro. Final 09/02 117**  **- 81**  **- 7**  **Ch r. 0.06 mg/kg/day 100 Repro.**  **DIETHYL PHTHALATE Oral Acute 7 mg/kg/day 300 Repro. Final 06/95 84**  **- 66**  **- 2**  **Int. 6 mg/kg/day 300 Hepatic**

**DIISOPROPYL METHYLPHOS PHONATE Oral Int. 0.8 mg/kg/day 100 Hemato. Final 10/98**  **1445 -**  **75 -**  **6**

**(DIMP) Chr. 0.6 mg/kg/day 100 Hemato. DIMETHYLARSINIC ACID (DMA) Oral Chr. 0.02 mg/kg/day 100 Renal**  **Final 08/07 75**  **- 60**  **- 5**  **1,1 -**  **DIMETHYLHYDRAZINE Inh. Int. 0.0002 ppm 300 Hepatic Final 09/97 57**  **- 14**  **- 7**  **1,2 -**  **DIMETHYLHYDRAZINE Oral Int. 0.0008 mg/kg/day 1000 Hepatic Final 09/97 540**  **- 73**  **- 8**  **1,3 -**  **DINITROBENZENE Oral Acute 0.008 mg/kg/day 100 Repro. Final 06/95 99**  **- 65**  **- 0**  **Int. 0.0005 mg/kg/day 1000 Hemato.**

### Dec ember 2010 ATSDR Minimal Risk Levels Page 7 of 14 **4,6 -**  **DINITRO -**  **O -**  **CRESOL Oral Acute 0.004 mg/kg/day 100 Neurol. Final 08/95**  **534 -**  **52 -**  **1 Int. 0.004 mg/kg/day 100 Neurol.**  **2,4 -**  **DINITROPHENOL Oral Acute 0.01 mg/kg/day 100 Body Wt. Final 08/95 51**  **- 28**  **- 5**  **2,4 -**  **DINITROTOLUENE Oral Acute 0.05 mg/kg/day 100 Neurol. Final 12/98 121**  **- 14**  **- 2**  **Chr. 0.002 mg/kg/day 100 Hemato. 2,6**  **- DINITROTOLUENE Oral Int. 0.004 mg/kg/day**  **1000 Hemato. Final 12/98 606**  **- 20**  **- 2** 

**DI -**  **N -**  **OCTYL PHTHALATE Oral Acute 3 mg/kg/day 300 Hepatic Final 09/97 117**  **- 84**  **- 0**  **Int. 0.4 mg/kg/day 100 Hepatic**

**1,4 -**  **DIOXANE Inh. Acute 2 ppm 30 Ocular Draft 09/07 123**  **- 91**  **- 1**  **Int. 1 ppm 30 Hepatic Chr. 1 ppm**  **30 Hepatic Oral Acute 4 mg/kg/day 100 Resp.**  **Int. 0.6 mg/kg/day 100 Hepatic Chr. 0.1 mg/kg/day 100**  **Hepatic DISULFOTON Inh. Acute 0.006 mg/m3 30 Neurol. Final 08/95**  **298 -**  **04 -**  **4 Int. 0.0002 mg/m3 30 Neurol.**  **Oral Acute 0.0 01 mg/kg/day 100 Neurol.**  **Int. 0.00009 mg/kg/day 100 Develop. Chr. 0.00006 mg/kg/day 1000 Neurol.**  **ENDOSULFAN Oral Int. 0.005 mg /kg/day 100 Immuno. Final 09/00**  **115 -**  **29 -**  **7 Chr. 0.002 mg/kg/day 100 Hepatic**  **ENDRIN Oral Int. 0.002 mg/kg/day 100 Neurol. Final 08/96 72**  **- 20**  **- 8**  **Chr. 0.0003 mg/kg/day 100 Neurol. ETHION Oral Acute 0.002 mg/kg/day 30 Neurol. Final 09/00**  **563 -**  **12 -**  **2 Int. 0.002 mg/kg/**  **day 30 Neurol. Chr. 0.0004 mg/kg/day 150 Neurol.** 

**ETHYLBENZENE Inh. Acute 5**  **ppm 30 Neurol.**  **Final 11/10 100**  **- 41**  **- 4**  **Int. 2**  **ppm 30 Neurol.**  **Chr. 0. 06**  **ppm 300 Renal Oral Int. 0.**  **4 mg/kg/day**  **3 0**  **Hepatic**

**ETHYLENE GLYCOL Inh. Acute 2 mg/m3 10 Resp.**  **Final 11/10 107**  **- 21**  **- 1**  **Oral Acute 0.8 mg/kg/day 100 Develop. Int. 0.8 mg/kg/day 100 Develop.** 

### Dec ember 2010 ATSDR Minimal Risk Levels Page 8 of 14 **ETHYLENE OXIDE Inh. Int. 0.09 ppm 100 Renal Final 12/90 75**  **- 21**  **- 8**  **FLUORANTHENE Oral Int. 0.4 mg/kg/day 300 Hepatic Final 08/95 206**  **- 44**  **- 0** 

**FLUORENE Oral Int. 0.4 mg/kg/day 300 Hepatic Final 08/95**  **86 -**  **73 -**  **7 FLUORIDE, SODIUM Oral Chr. 0.05 mg/kg/day 3 Musculo. Final 09/03**  **7681 -**  **49 -**  **4 FLUORINE Inh. Acute 0.01 ppm**  **10 Resp. Final 09/03 7782**  **- 41**  **- 4**  **FORMALDEHYDE Inh. Acute 0.04 ppm 9 Resp. Final 07/99 50**  **- 00**  **- 0**  **Int. 0.03 ppm 30 Resp. Chr. 0.008 ppm 30 Resp.**  **Oral Int. 0.3 mg/kg/day 100 Gastro. Chr. 0.2 mg/kg/day 100 Gastro.**  **FUEL OIL NO.2 Inh. Acute 0.02 mg/m3 1000 Neurol. Final 06/95 68476**  **- 30**  **- 2**  **GUTHION (AZINPHOS -**  **METHYL) Inh. Acute 0.02 mg/m3 30 Neurol. Final 09/08**  **86 -**  **50 -**  **0 Int. 0.01 mg/m3 30 Neurol.**  **Chr. 0.01 mg/m3 30 Neurol. Oral Acute 0.01 mg/kg/day 100 Neurol.**  **Int. 0.003 mg/kg/day 100 Neurol. Chr. 0.003 mg/kg/day 100 Neurol.**  **HEPTACHLOR Oral Acute 0.0006 mg/kg/day 3000 Repro. Final 08/07 76**  **- 44**  **- 8**  **Int. 0.0001 mg/kg/day 300 Immuno. HEXACHLOROBENZENE Oral Acute 0.008 mg/kg/day 300 Develop. Final 09/02**  **118 -**  **74 -**  **1 Int. 0.0001 mg/kg**  **/day 90 Repro. Chr. 0.00005 mg/kg/day 300 Develop.**  **HEXACHLOROBUTADIENE Oral Int. 0.0002 mg/kg/day 1000 Renal Final 05/94 87**  **- 68**  **- 3** 

**ALPHA -**  **HEXACHLOROCYCLOHEXANE Or**  **al Chr. 0.008 mg/kg/day 100 Hepatic Final 09/05 319**  **- 84**  **- 6** 

**BETA -**  **HEXACHLOROCYCLOHEXANE Oral Acute 0.05 mg/kg/day 100 Neurol. Final 09/05**  **319 -**  **85 -**  **7 Int. 0.0006 mg/kg/day 3**  **00 Hepatic**

**GAMMA -**  **HEXACHLOROCYCLOHEXANE Oral Acute 0.003 mg/kg/day 300 Develop. Final 09/05**  **58 -**  **89 -**  **9 Int. 0.00001 mg/kg/day 1000 Immuno.** 

### Dec ember 2010 ATSDR Minimal Risk Levels Page 9 of 14 **HEXACHLOROCYCLOPENTADIENE Inh. Int. 0.01 ppm 30 Resp. Final 07/99**  **77 -**  **47 -**  **4 Chr. 0.0002 ppm 90 Resp.**  **Oral Int. 0.1 mg/kg/day 100 Renal**

**HEXACHLOROETHANE Inh. Acute 6 ppm 30 Neurol. Final 09/97**  **67 -**  **72 -**  **1 Int. 6 ppm 30 Neurol.**  **Oral Acute 1 mg/kg/day 100 Hepatic Int. 0.01 mg/kg/day 100 Hepatic**  **HEXAMETHYLENE DIISOCYANATE Inh. Int. 0.00003 ppm 30 Resp. Final 10/98 822**  **- 06**  **- 0**  **Chr. 0.00001 ppm 90 Resp.** 

**N -**  **HEXANE Inh. Chr. 0.6 ppm 100 Neurol. Final 07/99**  **110 -**  **54 -**  **3 HMX (**  **CYCLOTETRAMETHYLENE Oral Acute 0.1 mg/kg/day 1000 Neurol. Final 09/97**  **2691 -**  **41 -**  **0 TETRANITRAMINE) Int. 0.05 mg/kg/day 1000 Hepatic**  **HYDRAZINE Inh. Int. 0.004 ppm 300 Hepatic Final 09/97 302**  **- 01**  **- 2**  **HYDROGEN FLUORIDE Inh. Acute 0.02 ppm 30 Resp. Final 09/03**  **7664 -**  **39 -**  **3 HYDROGEN SULFIDE Inh. Acute 0.07 ppm 27 Resp. Final 07/06**  **7783 -**  **06 -**  **4 Int. 0.02 ppm 30 Resp.** 

**IODIDE Oral Acute 0.01 mg/kg/day 1 Endocr. Final 10/04**  **7553 -**  **56 -**  **2 Chr. 0.01 mg/kg/day 1 Endocr.**  **IONIZING RADIATION, N.O.S. Rad. Acute 4 mSv 3 Neurol. Final 09/99 HZ1800**  **- 45**  **- T**  **Chr. 1 mSv/yr 3 Other ISOPHORONE Oral Int. 3 mg/kg/day 100 Other Final 12/89**  **78 -**  **59 -**  **1 Chr. 0.2 mg/kg/day 1000 Hepatic** 

**JP -**  **4 Inh. Int. 9 mg/m3 300 Hepatic Final 06/95 50815**  **- 00**  **- 4** 

**JP -**  **5/JP -**  **8 Inh. Int. 3 mg/m3 300 Hepatic Final 10/98 HZ0600**  **- 26**  **- T** 

**JP -**  **7 Inh. Chr. 0.3 mg/m3 300 Hepatic Final 06/95 HZ0600 -**  **22 -**  **T KEROSENE Inh. Int. 0.01 mg/m3 1000 Hepatic Final**  **06/95 8008**  **- 20**  **- 6** 

### Dec ember 2010 ATSDR Minimal Risk Levels Page 10 of 14 **MALATHION Inh. Acute 0.2 mg/m3 100 Neurol. Final 09/03 121**  **- 75**  **- 5**  **Int. 0.02 mg/m3 1000 Resp. Oral In**  **t. 0.02 mg/kg/day 10 Neurol. Chr. 0.02 mg/kg/day 100 Neurol.**  **MANGANESE, RESPIRABLE Inh. Chr. 0.0 4**  **u g/m3**  **5 00 Neurol.**  **Addendum 09/**  **10 7439**  **- 96**  **- 5** 

**MERCURIC CHLORIDE Oral Acute 0.007 mg/kg/day 100 Renal Final 03/99**  **7487 -**  **94 -**  **7 Int. 0.002 mg/kg/day 100 Renal**  **MERCURY Inh. Chr. 0.0002 mg/m3 30 Neurol. Final 03/99**  **7439 -**  **97 -**  **6 METHOXYCHLOR Oral Int. 0.005 mg/kg/day 1000 Repro.**  **F inal**  **09/0 2**  **72 -**  **43 -**  **5 4,4'**  **- METHYLENEBIS(2**  **- CHLOROANILINE) Oral Chr. 0.003 mg/kg/day 3000 Hepatic Final 05/94**  **101 -**  **14 -**  **4 METHYLENE CHLORIDE Inh. Acute 0.6 ppm 100 Neurol. Final 09/00**  **75 -**  **09 -**  **2 Int. 0.3 ppm 90 Hepatic**  **Chr. 0.3 ppm 30 Hepatic**  **Oral Acute 0.2 mg/kg/day 100 Neurol. Chr. 0.06 mg/kg/day 100 Hepatic** 

**4,4' -**  **METHYLENEDIANILINE Oral Acute 0.2 mg/kg/day 300 Hepatic Final 10/98**  **101 -**  **77 -**  **9 Int. 0.08 mg/kg/day 100 Hepatic**  **METHYLMERCURY Oral Chr. 0.0003 mg/kg/day 4.5 Develop. Final 03/99 22967**  **- 92**  **- 6** 

**1 -**  **METHYLNAPHTHALE NE Oral Chr. 0.07 mg/kg/day 1000 Resp. Final 09/05**  **90 -**  **12 -**  **0**

**2 -**  **METHYLNAPHTHALENE Oral Chr. 0.04 mg/kg/day 100 Resp. Final 09/05 91**  **- 57**  **- 6** 

**METHYL PARATHION Oral Int. 0.0007 mg/kg/day 300 Neurol. Final 09/01**  **298 -**  **00 -**  **0 Chr. 0.0003 mg/kg/day 100 Hemato.** 

**METHYL -**  **T -**  **BUTYL ETHER Inh. Acute 2 ppm 100 Neurol. Final 08/96 1634**  **- 04**  **- 4**  **Int. 0.7 ppm 100 Neurol. Chr. 0.7 ppm 100 Renal**  **Oral Acute 0.4 mg/kg/day 100 Neurol. Int. 0.3 mg/kg/day 300 Hepatic**  **MIREX Oral Chr. 0.0008 mg/kg/day 100 Hepatic Final 08/95 2385**  **- 85**  **- 5** 

**MONOMETHYLARSONIC ACID Oral Int . 0.1 mg/kg/day 100 Gastro. Final 08/07**  **124 -**  **58 -**  **3**

**(MMA) Chr. 0.01 mg/kg/day 100 Renal**

### Dec ember 2010 ATSDR Minimal Risk Levels Page 11 of 14 **NAPHTHALENE Inh. Chr. 0.0007 ppm 300 Resp. Final 09/05 91**  **- 20**  **- 3**  **Oral Acute 0.6 mg/kg/day 90 Neurol. Int. 0.6 mg/kg/day 90 Neurol.** 

**N -**  **NITROSODI -**  **N -**  **PROPYLAMINE Oral Acute 0.095 mg/kg/day 100 Hepatic F inal 12/89**  **621 -**  **64 -**  **7 NICKEL Inh. Int. 0.0002 mg/m3 30 Resp.**  **Final 09/05 7440**  **- 02**  **- 0**  **Chr. 0.00009 mg/m3 30 Resp. 2,3,4,7,8**  **- PENTACHLORODIBENZOFURAN O**  **ral Acute 0.001 ug/kg/day 3000 Immuno. Final 05/94 57117**  **- 31**  **- 4**  **Int. 0.00003 ug/kg/day 3000 Hepatic PENTACHLOROPHENOL Oral Acute 0.005 mg/kg/day 1000 Develop. Final 09/01**  **87 -**  **86 -**  **5 Int. 0.001 mg/kg/day 1000 Repro.**  **Chr. 0.001 mg/kg/day 1000 Endocr. PERCHLORATES Oral Chr. 0.0007 mg/kg/day 10 E**  **ndocr. Final 08/08 7778**  **- 74**  **- 7**  **PERMETHRIN Oral Acute 0.3 mg/kg/day 100 Neurol. Final 09/03 52645**  **- 53**  **- 1**  **Int. 0.2 mg/kg/day 100 Neurol.**

**PHENOL Oral Acute 1 mg/kg/day 100 Body Wt. Final 09/08**  **108 -**  **95 -**  **2 PHOSPHORUS, WHITE Inh. Acute 0.02 mg/m3 30 Resp. Final 09/97**  **7723 -**  **14 -**  **0 Oral Int**  **. 0.0002 mg/kg/day 100 Repro. POLYBROMINATED BIPHENYLS (PBBs) Oral Acute 0.01 mg/kg/day 100 Endocr. Final 10/04**  **36355 -**  **01 -**  **8 POLYBROMINATED DIPHENYL ETHERS Inh Int. 0.006 mg/m3 90 Endocr. Final 10/04**  **32534 -**  **81 -**  **9 (PBDEs), LOWER BROMINATED Oral Acute 0.03 mg/kg/day 30 Endocr.**  **32536 -**  **52 -**  **0 Int. 0.007 mg/kg/day 300 Hepatic**  **PBDEs, DECABROMINATED Oral Int. 10 mg/k g/day 100 Develop. Final 10/04**  **1163 -**  **19 -**  **5 POLYCHLORINATED BIPHENYLS (PCBs) Oral Int. 0.03 ug/kg/day 300 Neurol. Final 11/00**  **11097 -**  **69 -**  **1**

**(Aroclor 1254) Chr. 0.02 ug/kg/day 300 Immuno.**

**PROPY LENE GLYCOL Inh. Int. 0.009 ppm 1000 Resp. Final 09/97**  **57 -**  **55 -**  **6 PROPYLENE GLYCOL DINITRATE Inh. Acute 0.003 ppm 10 Neurol. Final 06/95**  **6423 -**  **43 -**  **4 Int. 0.00004 ppm 1000 Hemato.**  **Chr. 0.00004 ppm 1000 Hemato.**

### Dec ember 2010 ATSDR Minimal Risk Levels Page 12 of 14 **RDX ( CYCLOTRIMETHYLENETRINITRAMINE**  **) Oral Acute 0.0**  **9 mg/kg/day 100 Neurol.**  **Draf t 07/10**  **121 -**  **82 -**  **4 Int. 0.0**  **5 mg/kg/day**  **1 00**  **Neu ro**  **l .**  **REFRACTORY CERAMIC FIBERS Inh. Chr. 0.03 fibers/cc 30 Resp. Final 10/04 HZ0900 -**  **26 -**  **T**

**SELENIUM Oral Chr. 0.005 mg/kg/day 3 Dermal Final 09/03**  **7782 -**  **49 -**  **2 STRONTIUM Oral Int. 2 mg/kg/day 30 Musculo. Final 10/04**  **7440 -**  **24 -**  **6**

**STYRENE Inh. Acute 5**  **ppm 10 Neurol.**  **Final 11/10 100**  **- 42**  **- 5**  **Chr. 0.2 ppm 3**  **0 Neurol. Oral Acute 0.1 mg/kg/day 1000 Neurol.** 

**SULFUR DIOXIDE Inh. Acute 0.01 ppm 9 Resp. Final 12/98**  **7446 -**  **09 -**  **5 SULFUR MUSTARD Inh. Acute 0.0007 mg/m3 30 Ocular Final 09/03**  **505 -**  **60 -**  **2 Int. 0.00002 mg/m3**  **30 Ocular Oral Acute 0.5 ug/kg/day 1000 Develop.**  **Int. 0.07 ug/kg/day 300 Gastro. 2,3,7,8**  **- TETRACHLORODIBENZO**  **- P**  **- DIOXIN Oral Acute 0.0002 ug/kg/day**  **21 Immuno. Final 12/98 1746**  **- 01**  **- 6**  **Int. 0.00002 ug/kg/day 30 Lymphor. Chr. 0.000001 ug/kg/day 90 Develop.**  **1,1,2,2 -**  **TETRACHLOROETHANE Oral Int. 0.5 mg/kg/day 100 Hepatic Final 09/08 79**  **- 34**  **- 5**  **TETRACHLOROETHYLENE Inh. Acute 0.2 ppm 10 Neurol. Final 09/97 127**  **- 18**  **- 4**  **Chr. 0.04 ppm 100 Neurol. Oral Acute 0.05 mg/kg/day 100 Develop.**  **TIN, INORGANIC Oral Int. 0.3 mg/kg/day 100 Hemato. Final 09/05 7440**  **- 31**  **- 5** 

**TIN, DIBUTYL -**  **, D ICHLORIDE Oral Int. 0.005 mg/kg/day**  **1000 Immuno.**  **Final 09/05 683**  **- 18**  **- 1** 

**TIN, TRIBUTYL -**  **, OXIDE Oral Int. 0.0003 mg/kg/day 100 Immuno.**  **Final 09/05 56**  **- 35**  **- 9**  **Chr. 0.0003 mg/kg/day 100**  **Immuno. TITANIUM TETRACHLORIDE Inh. Int. 0.01 mg/m3 90 Resp. Final**  **09/97 7550**  **- 45**  **- 0**  **Chr. 0.0001 mg/m3 90 Resp.**

**TOLUENE Inh. Acute 1 ppm 10 Neurol. Final 09/00**  **108 -**  **88 -**  **3 Chr. 0.08 ppm 100 Neurol.**  **Oral Acute 0.8 mg/kg/day 300 Neurol. Int. 0.02 mg/kg/day 300 Neurol.** 

### Dec ember 2010 ATSDR Minimal Risk Levels Page 13 of 14 **TOXAPHENE Oral Acute 0.05 mg/kg/day 100**  **Neurol. Draft**  **9 /**  **10 8001**  **- 35**  **- 2**  **Int. 0.00 2**  **mg/kg/day 1**  **00 Immuno.**  **TRIBUTYL PHOSPHATE Oral Acute 1.1 mg/kg/day 100 Body Wt. Draft 09/09 126**  **- 73**  **- 8**  **(TnBP) Int. 0.02 mg/kg/day 100 Renal Chr. 0.02 mg/kg/day 100 Renal**  **1,2,4 -**  **TRICHLOROBENZENE Oral Int. 0.1 mg/kg/day 100 Hepatic Draft 9/10 120**  **- 8**  **2 -**  **1 Chr. 0.1 mg/kg/day 100 Hepatic**  **1,1,1 -**  **TRICHLOROETHANE Inh. Acute 2 ppm 100 Neurol. Final 07/06 71**  **- 55**  **- 6**  **Int. 0.7 ppm 100 Neurol. Oral Int. 20 mg/kg/day**  **100 Body Wt. 1,1,2**  **- TRICHLOROETHANE Oral Acute 0.3 mg/kg/day 100 Neurol. Final 12/89**  **79 -**  **00 -**  **5 Int. 0.04 mg/kg/day 100 Hepatic** 

**TRICHLOROETHYLENE Inh. Acute 2 ppm 30 Neurol. Final 09/97**  **79 -**  **01 -**  **6 Int. 0.1 ppm 300 Neurol.**  **Oral Acute 0.2 mg/kg/day 300 Develop. 1,2,3**  **- TRICHLOROPROP**  **ANE Inh. Acute 0.0003 ppm 100 Resp. Final 09/92 96**  **- 18**  **- 4**  **Oral Int. 0.08 mg/kg/day 100 Hepatic**

**2,4,6 -**  **TRINITROTOLUENE Oral Int. 0.0005 mg/kg/day 1000 Hepatic Final 06/95**  **118 -**  **96 -**  **7 TRIS(2**  **- BUTOXYETHYL) PHOSPHATE**  **Oral Acute 4.8 mg/kg/day 100 Body Wt. Draft 09/09 78**  **- 51**  **- 3**  **(TBEP) Int. 0.2 mg/kg/day 100 Hepatic**

**TRIS(2 -**  **CHLOROETHYL) PHOS PHATE Oral Int. 0.6 mg/kg/day 100 Neurol. Draft 09/09**  **115 -**  **96 -**  **8 (TCEP) Chr. 0.3 mg/kg/day 100 Renal**  **TRIS(1,3 -**  **DICHLORO -**  **2 -**  **PROPYL) Oral Int. 0.05 mg/kg/day 100 Renal Dr aft 09/09**  **13674 -**  **87 -**  **8 PHOSPHATE (TDCP) Chr. 0.02 mg/kg/day 100 Renal**  **URANIUM, HIGHLY SOLUBLE SALTS Inh. Int. 0.0004 mg/m3 90 Renal Final 09/99 HZ1800 -**  **90 -**  **T Chr. 0.0003 mg/m3 30 Renal**  **Oral Int. 0.002 mg/kg/day 30 Renal URANIUM, INSOLUBLE COMPOUNDS Inh. Int. 0.008 mg/m3 30 Renal Final 0**  **9/99 HZ1800 -**  **92 -**  **T**

### Dec ember 2010 ATSDR Minimal Risk Levels Page 14 of 14 **VANADIUM Inh. Acute 0.0008 mg/m3 90 Resp. Draft 09/09**  **7440 -**  **62 -**  **2 Chr. 0.0001 mg/m3 30 Resp.**  **Oral Int . 0.01**  **mg/kg/day 10 Hemato.**  **VINYL ACETATE Inh. Int. 0.01 ppm 100 Resp. Final 07/92 108**  **- 05**  **- 4**  **VINYL CHLORIDE Inh. Acute 0.5 ppm 30 Develop. Final 07/06 75**  **- 01**  **- 4**  **Int. 0.03 ppm 30 Hepatic Oral Chr. 0.003 mg/kg/day 30 Hepatic**  **XYLENES, MIXED Inh. Acute 2 ppm 30 Neurol. Final 08/07**  **1330 -**  **20 -**  **7 Int. 0.6 ppm 90 Neurol.**  **Chr. 0.05 ppm 300 Neurol. Ora**  **l Acute 1 mg/kg/day**  **100 Neurol. Int. 0.4 mg/kg/day 1000 Neurol.**  **Chr. 0.2 mg/kg/day 1000 Neurol. ZINC Oral Int. 0.3 mg/kg/day**  **3 Hemato. Final 09/05 7440**  **- 66**  **- 6**  **Chr. 0.3 mg/kg/day 3 Hemato.**

**______________________________________________________________________________________________________________ Total number of MRLs:**  **3 94**  **For Duration, Acute = 1 to 14 days, Intermediate = 15 to 364 days, and Chronic = 1 year or longer. For general information on ATSDR Minimal Risk Levels, see www.atsdr.cdc.gov/mrls.**  **For more information on a specific MRL, please refer to our Toxicological Profiles,**  **particularly Appendix A of Profiles written after 1995. The Profiles can be found online at**  **www.astdr.cdc.gov or ordered via**  **cdcinfo@cdc.gov or 1**  **- 800**  **- CDC**  **- INFO.**