Exhibit 10.47


Amendment to License Agreement


This will amend the license agreement between Micro
Therapeutics, Inc. (“MTI”) and Biocoat, Inc. (“Biocoat”) of December 9, 1999
(the “Agreement” and this “Amendment”).


The effective date of
this Amendment is January 1, 2005.


Schedule A of the
Agreement, listing the Products, is hereby replaced with the attached Schedule
A, dated November 4, 2004.


MTI hereby represents
that it intends to use the hydrophilic coatings technology licensed from
Biocoat for the Products listed in the attached Schedule A for the remaining
term of the Agreement.


In consideration of this
representation of MTI, Biocoat agrees to replace the Royalty Rate 

Schedule of the Agreement, Schedule D, with the attached Schedule D, dated
November 

4, 2004.


Both parties to the
Agreement hereby signify their approval of this Amendment.


	
  /s/Djoerd Hoekstra, President

  	
   

  	
  /s/William H. Dippel

  	
   

  	
   

  
	
  Djoerd Hoekstra, President

  	
   

  	
  William H. Dippel, V.P. Operations

  	
   

  	
   

  
	
  Biocoat, Inc.

  	
   

  	
  Micro Therapeutics, Inc.

  	
   

  	
   

  
	
  Date:

  	
  12/09/04

  	
   

  	
   

  	
  Date:

  	
  12/10/04

  	
   

  	
   

  	
   

  
									



 











SCHEDULE A


PRODUCTS


	
   

  	
   

  	
  Model #

  	
   

  	
  Description

  
	
   

  	
   

  	
   

  	
   

  	
   

  
	
  HYPERFORM

  	
   

  	
  104-4470

  	
   

  	
  HYPERFORM 4.0 X 7 MM SYS

  
	
  HYPERFORM

  	
   

  	
  104-4770

  	
   

  	
  HYPERFORM 7.0 X 7 MM SYS

  
	
  HYPERGLIDE

  	
   

  	
  104-41 08

  	
   

  	
  HYPERGLIDE 15 MM ST BALL

  
	
  HYPERGLIDE

  	
   

  	
  104-4112

  	
   

  	
  HYPERGLIDE 4.0 X 15 MM,

  
	
  HYPERGLIDE

  	
   

  	
  104-4113

  	
   

  	
  HYPERGLIDE 4.0X10 MM

  
	
  HYPERGLIDE

  	
   

  	
  104-4120

  	
   

  	
  HYPERGLIDE, 10 MM ST BAL

  
	
  HYPERGLIDE

  	
   

  	
  104-4127

  	
   

  	
  HYPERGLIDE 4.0 X 20 MM,

  
	
  HYPERGLJDE

  	
   

  	
  104-4130

  	
   

  	
  HYPERGLIDE 20MM ST BALL

  
	
  HYPERGLIDE

  	
   

  	
  104-4131

  	
   

  	
  HYPERGLIDE 30 MM ST BALL

  
	
  HYPERGLIDE

  	
   

  	
  104-4132

  	
   

  	
  HYPERGLIDE SYSTEM- 30MM

  
	
  ULTRAFLOW

  	
   

  	
  105-5065

  	
   

  	
  ULTRAFLOW HPC 1 .5F FLOW

  
	
  ULTRAFLOW

  	
   

  	
  105-5066

  	
   

  	
  ULTRAFLOW EXTENDED

  
	
  REBAR IR (FG)

  	
   

  	
  105-5081-110

  	
   

  	
  REBAR-18, 110CM, MICRO C

  
	
  REBAR IR (FG)

  	
   

  	
  105-5081-130

  	
   

  	
  REBAR-18, 130CM, MICRO C

  
	
  REBAR IR (FG)

  	
   

  	
  105-5081-153

  	
   

  	
  REBAR-18, 153CM, M1CRO C

  
	
  REBAR IR (FG)

  	
   

  	
  105-5082-110

  	
   

  	
  REBAR-027, 110CM MICRO

  
	
  REBAR IR (FG)

  	
   

  	
  105-5082-130

  	
   

  	
  REBAR-027, 130CM, MICRO

  
	
  REBAR IR (FG)

  	
   

  	
  105-5082-145

  	
   

  	
  REBAR-027, 145CM, MICRO

  
	
  REBAR INR (FG)

  	
   

  	
  105-5078-153

  	
   

  	
  REBAR-l0, 153 CM, MICRO

  
	
  REBAR INR (FG)

  	
   

  	
  105-5078-153C

  	
   

  	
  REBAR-l0, 153 CM, MICRO

  
	
  REBAR INR (FG)

  	
   

  	
  105-5078-1 70

  	
   

  	
  REBAR-l0, 170 CM, MICRO

  
	
  REBAR INR (FG)

  	
   

  	
  105-5078-170C

  	
   

  	
  REBAR-l0, 170 CM, MICRO

  
	
  REBAR INR (FG)

  	
   

  	
  105-5080-143

  	
   

  	
  REBAR-14, 143CM, MICRO C

  
	
  REBAR INR (FG)

  	
   

  	
  105-5080-143C

  	
   

  	
  REBAR-14, 143CM, MICRO C

  
	
  REBAR INR (FG)

  	
   

  	
  105-5080-153

  	
   

  	
  REBAR-14, 153CM, MICRO C

  
	
  REBAR INR (FG)

  	
   

  	
  105-5080-153C

  	
   

  	
  REBAR-14, 153CM, MICRO C

  
	
  REBAR INR (FG)

  	
   

  	
  105-5080-1 70

  	
   

  	
  REBAR-14, 170CM MICRO CA

  
	
  REBAR INR (FG)

  	
   

  	
  105-5080-170C

  	
   

  	
  REBAR-14, 170CM MICRO

  
	
  REBAR INR (FG)

  	
   

  	
  105-5083-153

  	
   

  	
  REBAR-18, 153 MICRO CATH

  
	
  REBAR INR (FG)

  	
   

  	
  105-5084-110

  	
   

  	
  REBAR-18, SOFT TIP, 110

  
	
  REBAR INR (FG)

  	
   

  	
  105-5084-130

  	
   

  	
  REBAR-18, SOFT TIP, 130

  
	
  REBAR INR (FG)

  	
   

  	
  105-5084-143

  	
   

  	
  REBAR-18, SOFT TIP, 143

  
	
  REBAR INR (FG)

  	
   

  	
  105-5084-153

  	
   

  	
  REBAR-18, SOFT TIP, 153

  
	
  REBAR INR (FG)

  	
   

  	
  105-5085-143

  	
   

  	
  REBAR-18, SOFT TIP, 143

  
	
  REBAR INR (FG)

  	
   

  	
  105-5085-153

  	
   

  	
  REBAR-18, SOFT TIP, 153

  
	
  ECHELON

  	
   

  	
  105-5091-1 50

  	
   

  	
  ECHELON 10 MICRO

  
	
  ECHELON

  	
   

  	
  105-5092-1 50

  	
   

  	
  ECHELON 14 MICRO

  
	
  ECHELON

  	
   

  	
  145-5091-1 50

  	
   

  	
  ECHELON 10, 45 DEGREE

  
	
  ECHELON

  	
   

  	
  190-5091-1 50

  	
   

  	
  ECHELON 10, 90 DEGREE

  
	
  ECHELON

  	
   

  	
  145-8092-1 50

  	
   

  	
  ECHELON 14, 45 DEGREE

  
	
  ECHELON

  	
   

  	
  190-5092-150

  	
   

  	
  ECHELON 14, 90 DEGREE

  
	
  NAUTICA (FG)

  	
   

  	
  105-5094-153

  	
   

  	
  NAUTICA MICROCATHETER

  
	
  MARATHON

  	
   

  	
  105-5055

  	
   

  	
  MARATHON MICROCATHETER

  



 











SCHEDULE D


ROYALTY RATE SCHEDULE


ROYALTY
RATE – Effective January 1, 2005


a.                                     For net sales up to $10 million U.S. dollars
in a given calendar year, the rate will be 1.5%


b.                                    For net sales in excess of$10 million U.S
dollars and up to $50 million U.S dollars in a calendar year, the rate will be
1%.


c.                                     For net sales in excess of $50 million U.S
dollars in a given calendar year, the rate will be .5%.