Federal Express

 December 2, 2013

OPPT Document Control Office (DCO)

EPA East Building Room E6428 (202-564-8930)

U.S. Environmental Protection Agency

1201 Constitution Avenue, NW 

Washington, DC 20004

ATTN: 40 CFR 799.5089; Docket ID Number EPA–HQ–OPPT–2009–0112

RE: : CASRN 68610-90-2 

Dear Sir/Madame: 

As requested by US EPA, encloses a summary of the data requested by 

EPA under the above TSCA Test Rule, available data on CASRN 68610-90-2 and structurally 

related analogues, as well as the data being submitted to the EPA with this letter are listed in Table 

1 (attached). The information is being submitted in both paper (one copy) and electronic (disk) 

formats.

With the exception of physical-chemical properties, information submitted on environmental fate as 

well as ecological and mammalian toxicity is for , a close structural 

analogue of the test rule chemical, 2-butenedioic acid (2E)-, di-C8-18-alkyl esters (68610-90-2). 

Because several studies are in German, robust summaries of these studies in English are also 

provided. If this information is inadequate, translations of the original studies can be provided upon 

request from EPA. 

Two studies requested by EPA are not included in this submission. The first, an OECD 422 

(combined repeated dose toxicity study with reproduction/developmental toxicity screening) on 

 is being finalized. BASF expects it can provide this study to EPA in the next several 

weeks. The second, is a chronic toxicity study in Daphnia. Although this study has not been 

performed, 68610-90-2 is unlikely to pose a significant exposure potential or environmental hazard 

given (a) its poor water solubility (< 0.15 mg/L), (b) biodegradation characteristics (> 60% @ 28 

days), and (c) low acute toxicity as demonstrated by tests on chemical surrogates in three different 

aquatic receptors. 

Test Rule Identification: 40 CFR § 799.5089 Testing of Certain High Production Volume 

Chemicals; Third Group of Chemicals.

Chemical Subject to Testing: 2-butenedioic acid (2E)-,di-C8-18-alkyl esters (CASRN 68610-90-2)

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Firm Providing Data: 

Contact Person: 

 

Based on the information provided, believes EPA has sufficient screening level information to 

assess the risks posed by 68610-90-2 to human health and environmental safety. However, 

is willing to consider providing EPA with copies of studies on surrogate chemistries summarized in 

Table1, but not provided at this time, if the Agency believes this additional information will aid its 

assessment of 68610-90-2. looks forward to EPA’s thoughts on the information provided. 

Should you have any questions or concerns, please contact the person noted above.

Sincerely,

Senior Toxicologist

Environment, Health & Safety

Enclosures:

 

 

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CAS 68610-90-2, Boiling Point

CAS 68610-90-2, Melting Point

CAS 68610-90-2, KOW, C8 Component

CAS 68610-90-2, KOW, C18 Component

CAS 68610-90-2, Vapor Pressure, C8 Component

CAS 68610-90-2, Vapor Pressure C18 Component

CAS 68610-90-2, Determination of Water Solubility

Cc: Dr. Paul Lewis, US EPA (Email to Lewis.paul@Epa.gov ) 

Mr. John Schaeffer, US EPA (Email to Schaeffer.john@Epa.gov ) 

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Table 1: Summary of Data Requested by USEPA, Data Available and Data Submitted to EPA on CASRN 68610-90-2

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