EXHIBIT 34.1  LOGO Report of Independent Registered Public Accounting Firm To theManagement of American Express Travel Related Services Company, Inc., We have examined managements assertion, included in the accompanying Report on Assessment of Compliance with Servicing Criteria of American
Express Travel Related Services Company, Inc. and American Express National Bank, that American Express Travel Related Services Company, Inc. (the Company, the Asserting Party, and the Servicer) complied
with the servicing criteria set forth in Item 1122(d) of the Securities and Exchange Commissions Regulation AB for all asset-backed securities transactions backed by credit and charge card receivables issued by the American Express Credit
Account Master Trust and the American Express Issuance Trust II for which transactions the Asserting Party acted as Servicer (the Platform), as of December 31, 2021 and for the period from January 1, 2021 through
December 31, 2021, excluding criteria 1122(d)(1)(iii), 1122(d)(1)(iv), 1122(d)(2)(iii), 1122(d)(2)(vi), 1122(d)(3)(iii), 1122(d)(4)(i), 1122(d)(4)(x), 1122(d)(4)(xi), 1122(d)(4)(xii), 1122(d)(4)(xiii), and 1122(d)(4)(xv), which the Company has
determined are not applicable to the servicing activities performed by it with respect to the Platform. Appendix B to managements assertion identifies the individual asset-backed transactions and securities defined by management as
constituting the Platform. The Companys management is responsible for its assertion and for the Companys compliance with the applicable servicing criteria. Our responsibility is to express an opinion on managements assertion about
the Companys compliance with the applicable servicing criteria based on our examination. Our examination was conducted in accordance with the
standards of the Public Company Accounting Oversight Board (United States) and in accordance with attestation standards established by the American Institute of Certified Public Accountants. Those standards require that we plan and perform the
examination to obtain reasonable assurance about whether managements assertion about compliance with the applicable servicing criteria is fairly stated, in all material respects, and, accordingly, included examining, on a test basis, evidence
about the Companys compliance with the applicable servicing criteria and performing such other procedures as we considered necessary in the circumstances. Our examination included testing of selected asset-backed transactions and securities
that comprise the Platform, testing of selected servicing activities related to the Platform, and determining whether the Company processed those selected transactions and performed those selected activities in compliance with the applicable
servicing criteria. Our procedures were limited to the selected transactions and servicing activities performed by the Company during the period covered by this report. Our procedures were not designed to detect noncompliance arising from errors
that may have occurred prior to or subsequent to our tests that may have affected the balances or amounts calculated or reported by the Company during the period covered by this report. We believe that our examination provides, and that the evidence
we obtained is sufficient and appropriate to provide, a reasonable basis for our opinion. Our examination does not provide a legal determination on the Companys compliance with the servicing criteria. In our opinion, managements assertion that the Company complied with the aforementioned applicable servicing criteria as of and for the year ended
December 31, 2021 for the Platform is fairly stated, in all material respects. /s/ PricewaterhouseCoopers LLP New York, New York March 24, 2022